{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,29]],"date-time":"2026-10-29T04:39:10Z","timestamp":1793248750612,"version":"4.5.0"},"reference-count":50,"publisher":"Elsevier BV","issue":"9","license":[{"start":{"date-parts":[[2025,1,1]],"date-time":"2025-01-01T00:00:00Z","timestamp":1735689600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2025,1,1]],"date-time":"2025-01-01T00:00:00Z","timestamp":1735689600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2025,4,16]],"date-time":"2025-04-16T00:00:00Z","timestamp":1744761600000},"content-version":"vor","delay-in-days":105,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"funder":[{"DOI":"10.13039\/100009108","name":"Shandong University","doi-asserted-by":"publisher","award":["2020QNQT003"],"award-info":[{"award-number":["2020QNQT003"]}],"id":[{"id":"10.13039\/100009108","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100002858","name":"China Postdoctoral Science Foundation","doi-asserted-by":"publisher","award":["BX20230211"],"award-info":[{"award-number":["BX20230211"]}],"id":[{"id":"10.13039\/501100002858","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100002858","name":"China Postdoctoral Science Foundation","doi-asserted-by":"publisher","award":["2023M742123"],"award-info":[{"award-number":["2023M742123"]}],"id":[{"id":"10.13039\/501100002858","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100007129","name":"Shandong Province Natural Science Foundation","doi-asserted-by":"publisher","award":["ZR2024QH202"],"award-info":[{"award-number":["ZR2024QH202"]}],"id":[{"id":"10.13039\/501100007129","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100007129","name":"Shandong Province Natural Science Foundation","doi-asserted-by":"publisher","award":["ZR2021QB012"],"award-info":[{"award-number":["ZR2021QB012"]}],"id":[{"id":"10.13039\/501100007129","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100007129","name":"Shandong Province Natural Science Foundation","doi-asserted-by":"publisher","award":["ZR2022MH150"],"award-info":[{"award-number":["ZR2022MH150"]}],"id":[{"id":"10.13039\/501100007129","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100012226","name":"Fundamental Research Funds for the Central Universities","doi-asserted-by":"publisher","award":["2022JC008"],"award-info":[{"award-number":["2022JC008"]}],"id":[{"id":"10.13039\/501100012226","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100018546","name":"Postdoctoral Innovation Project of Shandong Province","doi-asserted-by":"publisher","award":["SDCX-ZG-202400065"],"award-info":[{"award-number":["SDCX-ZG-202400065"]}],"id":[{"id":"10.13039\/501100018546","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100014718","name":"Innovative Research Group Project of the National Natural Science Foundation of China","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100014718","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100010029","name":"Taishan Scholar Foundation of Shandong Province","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100010029","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["82270621"],"award-info":[{"award-number":["82270621"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["324B2029"],"award-info":[{"award-number":["324B2029"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["82400713"],"award-info":[{"award-number":["82400713"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["32270820"],"award-info":[{"award-number":["32270820"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","cmghjournal.org","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Cellular and Molecular Gastroenterology and Hepatology"],"published-print":{"date-parts":[[2025]]},"DOI":"10.1016\/j.jcmgh.2025.101523","type":"journal-article","created":{"date-parts":[[2025,4,24]],"date-time":"2025-04-24T04:04:45Z","timestamp":1745467485000},"page":"101523","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":4,"title":["The Role of the Hexosamine-Sialic Acid Metabolic Pathway Mediated by GFPT1\/NANS in c-Myc-Driven Hepatocellular Carcinoma"],"prefix":"10.1016","volume":"19","author":[{"given":"Shiguan","family":"Wang","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pan","family":"Han","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ping","family":"Mi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chunxue","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Miao","family":"Lu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xinying","family":"Li","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bowen","family":"Xu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Haoran","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yingchen","family":"Gao","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yanlei","family":"Hou","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xueying","family":"Tan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jinyuan","family":"Liang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xue","family":"Ding","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yan","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tingguo","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Detian","family":"Yuan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lei","family":"Gao","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Cuijuan","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.jcmgh.2025.101523_bib1","first-page":"394","article-title":"Global cancer statistics 2018: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries","volume":"68","author":"Bray","year":"2018","journal-title":"CA Cancer J Clin"},{"key":"10.1016\/j.jcmgh.2025.101523_bib2","doi-asserted-by":"crossref","first-page":"589","DOI":"10.1038\/s41575-019-0186-y","article-title":"A global view of hepatocellular carcinoma: trends, risk, prevention and management","volume":"16","author":"Yang","year":"2019","journal-title":"Nat Rev Gastroenterol Hepatol"},{"key":"10.1016\/j.jcmgh.2025.101523_bib3","doi-asserted-by":"crossref","first-page":"1264","DOI":"10.1053\/j.gastro.2011.12.061","article-title":"Epidemiology of viral hepatitis and hepatocellular carcinoma","volume":"142","author":"El-Serag","year":"2012","journal-title":"Gastroenterolgy"},{"key":"10.1016\/j.jcmgh.2025.101523_bib4","doi-asserted-by":"crossref","first-page":"541","DOI":"10.1016\/j.jcmgh.2023.06.006","article-title":"ZEB1 transcriptionally activates PHGDH to facilitate carcinogenesis and progression of HCC","volume":"16","author":"Wang","year":"2023","journal-title":"Cell Mol Gastroenterol Hepatol"},{"key":"10.1016\/j.jcmgh.2025.101523_bib5","doi-asserted-by":"crossref","first-page":"22","DOI":"10.1016\/j.cell.2012.03.003","article-title":"MYC on the path to cancer","volume":"149","author":"Dang","year":"2012","journal-title":"Cell"},{"key":"10.1016\/j.jcmgh.2025.101523_bib6","doi-asserted-by":"crossref","first-page":"593","DOI":"10.1038\/nrc3984","article-title":"MYC: connecting selective transcriptional control to global RNA production","volume":"15","author":"Kress","year":"2015","journal-title":"Nat Rev Cancer"},{"key":"10.1016\/j.jcmgh.2025.101523_bib7","doi-asserted-by":"crossref","first-page":"151","DOI":"10.3390\/genes8060151","article-title":"MYC deregulation in primary human cancers","volume":"8","author":"Kalkat","year":"2017","journal-title":"Genes (Basel)"},{"key":"10.1016\/j.jcmgh.2025.101523_bib8","doi-asserted-by":"crossref","first-page":"117","DOI":"10.1038\/s41392-021-00500-y","article-title":"Alternative approaches to target Myc for cancer treatment","volume":"6","author":"Wang","year":"2021","journal-title":"Signal Transduct Target Ther"},{"key":"10.1016\/j.jcmgh.2025.101523_bib9","doi-asserted-by":"crossref","first-page":"12556","DOI":"10.1073\/pnas.1319488111","article-title":"Inhibitor of MYC identified in a Kr\u00f6hnke pyridine library","volume":"111","author":"Hart","year":"2014","journal-title":"Proc Natl Acad Sci U S A"},{"key":"10.1016\/j.jcmgh.2025.101523_bib10","doi-asserted-by":"crossref","first-page":"369","DOI":"10.1101\/sqb.2011.76.011296","article-title":"Therapeutic targeting of Myc-reprogrammed cancer cell metabolism","volume":"76","author":"Dang","year":"2011","journal-title":"Cold Spring Harb Symp Quant Biol"},{"key":"10.1016\/j.jcmgh.2025.101523_bib11","doi-asserted-by":"crossref","first-page":"8322","DOI":"10.7150\/thno.62378","article-title":"Metabolic reprogramming of cancer-associated fibroblasts and its effect on cancer cell reprogramming","volume":"11","author":"Li","year":"2021","journal-title":"Theranostics"},{"key":"10.1016\/j.jcmgh.2025.101523_bib12","doi-asserted-by":"crossref","first-page":"669","DOI":"10.1038\/s41568-021-00378-6","article-title":"Cancer metabolism: looking forward","volume":"21","author":"Mart\u00ednez-Reyes","year":"2021","journal-title":"Nat Rev Cancer"},{"key":"10.1016\/j.jcmgh.2025.101523_bib13","doi-asserted-by":"crossref","first-page":"325","DOI":"10.1038\/nrc3038","article-title":"Otto Warburg's contributions to current concepts of cancer metabolism","volume":"11","author":"Koppenol","year":"2011","journal-title":"Nat Rev Cancer"},{"key":"10.1016\/j.jcmgh.2025.101523_bib14","first-page":"160","article-title":"Warburg effect in colorectal cancer: the emerging roles in tumor microenvironment and therapeutic implications","volume":"15","author":"Zhong","year":"2022","journal-title":"Oncology"},{"key":"10.1016\/j.jcmgh.2025.101523_bib15","doi-asserted-by":"crossref","first-page":"1635","DOI":"10.1136\/gutjnl-2013-305302","article-title":"PTEN antagonises Tcl1\/hnRNPK-mediated G6PD pre-mRNA splicing which contributes to hepatocarcinogenesis","volume":"63","author":"Hong","year":"2014","journal-title":"Gut"},{"key":"10.1016\/j.jcmgh.2025.101523_bib16","doi-asserted-by":"crossref","first-page":"72","DOI":"10.1038\/bjc.2012.559","article-title":"Activating oxidative phosphorylation by a pyruvate dehydrogenase kinase inhibitor overcomes sorafenib resistance of hepatocellular carcinoma","volume":"108","author":"Shen","year":"2013","journal-title":"Br J Cancer"},{"key":"10.1016\/j.jcmgh.2025.101523_bib17","doi-asserted-by":"crossref","first-page":"447","DOI":"10.3390\/cancers10110447","article-title":"Lipid metabolic reprogramming in hepatocellular carcinoma","volume":"10","author":"Nakagawa","year":"2018","journal-title":"Cancers"},{"key":"10.1016\/j.jcmgh.2025.101523_bib18","doi-asserted-by":"crossref","DOI":"10.7554\/eLife.56749","article-title":"A powerful drug combination strategy targeting glutamine addiction for the treatment of human liver cancer","volume":"9","author":"Jin","year":"2020","journal-title":"Elife"},{"key":"10.1016\/j.jcmgh.2025.101523_bib19","doi-asserted-by":"crossref","first-page":"1159","DOI":"10.1038\/bjc.2014.425","article-title":"Glutamine depletion by crisantaspase hinders the growth of human hepatocellular carcinoma xenografts","volume":"111","author":"Chiu","year":"2014","journal-title":"Br J Cancer"},{"key":"10.1016\/j.jcmgh.2025.101523_bib20","doi-asserted-by":"crossref","first-page":"11","DOI":"10.1016\/j.canlet.2021.01.010","article-title":"The hexosamine biosynthetic pathway and cancer: current knowledge and future therapeutic strategies","volume":"503","author":"Lam","year":"2021","journal-title":"Cancer Lett"},{"key":"10.1016\/j.jcmgh.2025.101523_bib21","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1186\/s12915-019-0671-3","article-title":"Fueling the fire: emerging role of the hexosamine biosynthetic pathway in cancer","volume":"17","author":"Akella","year":"2019","journal-title":"BMC Biol"},{"key":"10.1016\/j.jcmgh.2025.101523_bib22","doi-asserted-by":"crossref","first-page":"1179","DOI":"10.1016\/j.cell.2014.01.014","article-title":"Spliced X-box binding protein 1 couples the unfolded protein response to hexosamine biosynthetic pathway","volume":"156","author":"Wang","year":"2014","journal-title":"Cell"},{"key":"10.1016\/j.jcmgh.2025.101523_bib23","doi-asserted-by":"crossref","first-page":"1510","DOI":"10.1016\/j.jcmgh.2022.01.014","article-title":"Regulation of liver regeneration by hepatocyte O-GlcNAcylation in mice","volume":"13","author":"Robarts","year":"2022","journal-title":"Cell Mol Gastroenterol Hepatol"},{"key":"10.1016\/j.jcmgh.2025.101523_bib24","doi-asserted-by":"crossref","first-page":"845","DOI":"10.1038\/nrc1739","article-title":"Biomarkers in cancer staging, prognosis and treatment selection","volume":"5","author":"Ludwig","year":"2005","journal-title":"Nat Rev Cancer"},{"key":"10.1016\/j.jcmgh.2025.101523_bib25","doi-asserted-by":"crossref","first-page":"227","DOI":"10.1586\/14789450.2014.897611","article-title":"Lectin approaches for glycoproteomics in FDA-approved cancer biomarkers","volume":"11","author":"Badr","year":"2014","journal-title":"Expert Rev Proteomics"},{"key":"10.1016\/j.jcmgh.2025.101523_bib26","doi-asserted-by":"crossref","first-page":"57","DOI":"10.1038\/nature11247","article-title":"An integrated encyclopedia of DNA elements in the human genome","volume":"489","year":"2012","journal-title":"Nature"},{"key":"10.1016\/j.jcmgh.2025.101523_bib27","doi-asserted-by":"crossref","first-page":"7159","DOI":"10.1038\/s41467-022-34856-8","article-title":"PCGF1-PRC1 links chromatin repression with DNA replication during hematopoietic cell lineage commitment","volume":"13","author":"Takano","year":"2022","journal-title":"Nat Commun"},{"key":"10.1016\/j.jcmgh.2025.101523_bib28","doi-asserted-by":"crossref","first-page":"195","DOI":"10.1007\/978-1-4939-7380-4_17","article-title":"Analysis of ChIP-seq data in R\/Bioconductor","volume":"1689","author":"de Santiago","year":"2018","journal-title":"Methods Mol Biol"},{"key":"10.1016\/j.jcmgh.2025.101523_bib29","doi-asserted-by":"crossref","first-page":"4980","DOI":"10.1038\/s41467-020-18735-8","article-title":"c-Myc inactivation of p53 through the pan-cancer lncRNA MILIP drives cancer pathogenesis","volume":"11","author":"Feng","year":"2020","journal-title":"Nat Commun"},{"key":"10.1016\/j.jcmgh.2025.101523_bib30","doi-asserted-by":"crossref","first-page":"485","DOI":"10.1038\/s41419-018-0522-0","article-title":"O-GlcNAc elevation through activation of the hexosamine biosynthetic pathway enhances cancer cell chemoresistance","volume":"9","author":"Liu","year":"2018","journal-title":"Cell Death Dis"},{"key":"10.1016\/j.jcmgh.2025.101523_bib31","doi-asserted-by":"crossref","first-page":"55","DOI":"10.1038\/s41536-021-00163-x","article-title":"The Warburg effect is necessary to promote glycosylation in the blastema during zebrafish tail regeneration","volume":"6","author":"Sinclair","year":"2021","journal-title":"NPJ Regen Med"},{"key":"10.1016\/j.jcmgh.2025.101523_bib32","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pgen.1010128","article-title":"Cytosolic O-GlcNAcylation and PNG1 maintain Drosophila gut homeostasis by regulating proliferation and apoptosis","volume":"18","author":"Na","year":"2022","journal-title":"PLoS Genet"},{"key":"10.1016\/j.jcmgh.2025.101523_bib33","doi-asserted-by":"crossref","first-page":"3445","DOI":"10.1158\/0008-5472.CAN-17-2928","article-title":"GFPT2-expressing cancer-associated fibroblasts mediate metabolic reprogramming in human lung adenocarcinoma","volume":"78","author":"Zhang","year":"2018","journal-title":"Can Res"},{"key":"10.1016\/j.jcmgh.2025.101523_bib34","first-page":"2510","article-title":"GFPT2 promotes metastasis and forms a positive feedback loop with p65 in colorectal cancer","volume":"10","author":"Liu","year":"2020","journal-title":"Am J Cancer Res"},{"key":"10.1016\/j.jcmgh.2025.101523_bib35","doi-asserted-by":"crossref","first-page":"1401","DOI":"10.1038\/s42255-020-00316-0","article-title":"The hexosamine biosynthesis pathway is a targetable liability in KRAS\/LKB1 mutant lung cancer","volume":"2","author":"Kim","year":"2020","journal-title":"Nat Metab"},{"key":"10.1016\/j.jcmgh.2025.101523_bib36","doi-asserted-by":"crossref","DOI":"10.1038\/srep39044","article-title":"High expression of GFAT1 predicts poor prognosis in patients with pancreatic cancer","volume":"6","author":"Yang","year":"2016","journal-title":"Sci Rep"},{"key":"10.1016\/j.jcmgh.2025.101523_bib37","doi-asserted-by":"crossref","DOI":"10.3389\/fgene.2024.1482929","article-title":"Bioinformatics insights into the role of GFPT1 in breast invasive carcinoma: implications for tumor prognosis, immune modulation, and therapeutic implications","volume":"15","author":"Liang","year":"2024","journal-title":"Front Genet"},{"key":"10.1016\/j.jcmgh.2025.101523_bib38","doi-asserted-by":"crossref","first-page":"625","DOI":"10.1007\/s13105-021-00829-6","article-title":"FOXA2 inhibits doxorubicin-induced apoptosis via transcriptionally activating HBP rate-limiting enzyme GFPT1 in HCC cells","volume":"77","author":"Huang","year":"2021","journal-title":"J Physiol Biochem"},{"key":"10.1016\/j.jcmgh.2025.101523_bib39","doi-asserted-by":"crossref","first-page":"933","DOI":"10.3390\/genes14040933","article-title":"The hexosamine biosynthesis pathway: regulation and function","volume":"14","author":"Paneque","year":"2023","journal-title":"Genes (Basel)"},{"key":"10.1016\/j.jcmgh.2025.101523_bib40","doi-asserted-by":"crossref","first-page":"51","DOI":"10.1038\/s41413-022-00218-9","article-title":"Dynamic changes in O-GlcNAcylation regulate osteoclast differentiation and bone loss via nucleoporin 153","volume":"10","author":"Li","year":"2022","journal-title":"Bone Res"},{"key":"10.1016\/j.jcmgh.2025.101523_bib41","doi-asserted-by":"crossref","first-page":"E417","DOI":"10.1152\/ajpendo.00390.2011","article-title":"The hexosamine biosynthetic pathway and O-GlcNAcylation drive the expression of \u03b2-catenin and cell proliferation","volume":"302","author":"Olivier-Van Stichelen","year":"2012","journal-title":"Am J Physiol Endocrinol Metab"},{"key":"10.1016\/j.jcmgh.2025.101523_bib42","doi-asserted-by":"crossref","first-page":"547","DOI":"10.1016\/j.tibs.2010.04.005","article-title":"O-GlcNAc signaling: a metabolic link between diabetes and cancer?","volume":"35","author":"Slawson","year":"2010","journal-title":"Trends Biochem Sci"},{"key":"10.1016\/j.jcmgh.2025.101523_bib43","doi-asserted-by":"crossref","DOI":"10.1016\/j.bbcan.2022.188806","article-title":"The O-GlcNAcylation and its promotion to hepatocellular carcinoma","volume":"1877","author":"Zhang","year":"2022","journal-title":"Biochim Biophys Acta Rev Cancer"},{"key":"10.1016\/j.jcmgh.2025.101523_bib44","doi-asserted-by":"crossref","first-page":"805","DOI":"10.3390\/cells13100805","article-title":"Biological functions and potential therapeutic significance of O-GlcNAcylation in hepatic cellular stress and liver diseases","volume":"13","author":"Mao","year":"2024","journal-title":"Cells"},{"key":"10.1016\/j.jcmgh.2025.101523_bib45","doi-asserted-by":"crossref","first-page":"985","DOI":"10.1007\/s12032-011-9912-1","article-title":"O-GlcNAcylation plays a role in tumor recurrence of hepatocellular carcinoma following liver transplantation","volume":"29","author":"Zhu","year":"2012","journal-title":"Med Oncol"},{"key":"10.1016\/j.jcmgh.2025.101523_bib46","doi-asserted-by":"crossref","first-page":"1961","DOI":"10.1016\/j.cmet.2023.09.009","article-title":"High dietary fructose promotes hepatocellular carcinoma progression by enhancing O-GlcNAcylation via microbiota-derived acetate","volume":"35","author":"Zhou","year":"2023","journal-title":"Cell Metab"},{"key":"10.1016\/j.jcmgh.2025.101523_bib47","doi-asserted-by":"crossref","first-page":"207","DOI":"10.1038\/nmeth.1305","article-title":"High-efficiency labeling of sialylated glycoproteins on living cells","volume":"6","author":"Zeng","year":"2009","journal-title":"Nat Methods"},{"key":"10.1016\/j.jcmgh.2025.101523_bib48","doi-asserted-by":"crossref","first-page":"443","DOI":"10.1007\/s12253-015-0033-6","article-title":"Sialylation: an avenue to target cancer cells","volume":"22","author":"Vajaria","year":"2016","journal-title":"Pathol Oncol Res"},{"key":"10.1016\/j.jcmgh.2025.101523_bib49","doi-asserted-by":"crossref","first-page":"1471","DOI":"10.1016\/j.bbagen.2019.05.011","article-title":"Activity of N-acylneuraminate-9-phosphatase (NANP) is not essential for de novo sialic acid biosynthesis","volume":"1863","author":"Willems","year":"2019","journal-title":"Biochim Biophys Acta Gen Subj"},{"key":"10.1016\/j.jcmgh.2025.101523_bib50","doi-asserted-by":"crossref","first-page":"1640","DOI":"10.1016\/j.bbagen.2015.12.017","article-title":"Genetic defects in the hexosamine and sialic acid biosynthesis pathway","volume":"1860","author":"Willems","year":"2016","journal-title":"Biochim Biophys Acta"}],"container-title":["Cellular and Molecular Gastroenterology and Hepatology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2352345X25000645?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2352345X25000645?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,11,8]],"date-time":"2025-11-08T16:14:29Z","timestamp":1762618469000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S2352345X25000645"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025]]},"references-count":50,"journal-issue":{"issue":"9","published-print":{"date-parts":[[2025]]}},"alternative-id":["S2352345X25000645"],"URL":"https:\/\/doi.org\/10.1016\/j.jcmgh.2025.101523","relation":{},"ISSN":["2352-345X"],"issn-type":[{"value":"2352-345X","type":"print"}],"subject":[],"published":{"date-parts":[[2025]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"The Role of the Hexosamine-Sialic Acid Metabolic Pathway Mediated by GFPT1\/NANS in c-Myc-Driven Hepatocellular Carcinoma","name":"articletitle","label":"Article Title"},{"value":"Cellular and Molecular Gastroenterology and Hepatology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.jcmgh.2025.101523","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2025 The Authors. Published by Elsevier Inc. on behalf of the AGA Institute.","name":"copyright","label":"Copyright"}],"article-number":"101523"}}