{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,17]],"date-time":"2026-02-17T10:05:54Z","timestamp":1771322754352,"version":"3.50.1"},"reference-count":4,"publisher":"Elsevier BV","issue":"3","license":[{"start":{"date-parts":[[2026,1,1]],"date-time":"2026-01-01T00:00:00Z","timestamp":1767225600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2026,1,1]],"date-time":"2026-01-01T00:00:00Z","timestamp":1767225600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2025,11,8]],"date-time":"2025-11-08T00:00:00Z","timestamp":1762560000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","cmghjournal.org","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Cellular and Molecular Gastroenterology and Hepatology"],"published-print":{"date-parts":[[2026]]},"DOI":"10.1016\/j.jcmgh.2025.101677","type":"journal-article","created":{"date-parts":[[2025,11,17]],"date-time":"2025-11-17T02:42:55Z","timestamp":1763347375000},"page":"101677","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":0,"title":["Distinct chronic Pancreatitis Genetic Variants CPA1 N256K and PNLIP T221M Share Common Pathological Grounds"],"prefix":"10.1016","volume":"20","author":[{"given":"Michelle M.","family":"Cooley","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Guy E.","family":"Groblewski","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.jcmgh.2025.101677_bib1","doi-asserted-by":"crossref","first-page":"1692","DOI":"10.1007\/s10620-017-4601-3","article-title":"Genetic risk in chronic pancreatitis: the trypsin-dependent pathway","volume":"62","author":"Hegyi","year":"2017","journal-title":"Dig Dis Sci"},{"key":"10.1016\/j.jcmgh.2025.101677_bib2","doi-asserted-by":"crossref","first-page":"390","DOI":"10.1097\/MOG.0000000000000380","article-title":"Genetic risk in chronic pancreatitis: the misfolding-dependent pathway","volume":"33","author":"Sahin-Toth","year":"2017","journal-title":"Curr Opin Gastroenterol"},{"key":"10.1016\/j.jcmgh.2025.101677_bib3","doi-asserted-by":"crossref","first-page":"301","DOI":"10.1136\/gutjnl-2018-315994","article-title":"Human CPA1 mutation causes digestive enzyme misfolding and chronic pancreatitis in mice","volume":"68","author":"Hegyi","year":"2019","journal-title":"Gut"},{"key":"10.1016\/j.jcmgh.2025.101677_bib4","doi-asserted-by":"crossref","DOI":"10.1016\/j.jcmgh.2025.101638","article-title":"Diverse misfolding mutant digestive enzymes cause chronic pancreatitis through common pathways","volume":"20","author":"Wilhelm","year":"2026","journal-title":"Cell Mol Gastroenterol Hepatol"}],"container-title":["Cellular and Molecular Gastroenterology and Hepatology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2352345X25002188?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2352345X25002188?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,2,17]],"date-time":"2026-02-17T09:08:17Z","timestamp":1771319297000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S2352345X25002188"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026]]},"references-count":4,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2026]]}},"alternative-id":["S2352345X25002188"],"URL":"https:\/\/doi.org\/10.1016\/j.jcmgh.2025.101677","relation":{},"ISSN":["2352-345X"],"issn-type":[{"value":"2352-345X","type":"print"}],"subject":[],"published":{"date-parts":[[2026]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Distinct chronic Pancreatitis Genetic Variants CPA1 N256K and PNLIP T221M Share Common Pathological Grounds","name":"articletitle","label":"Article Title"},{"value":"Cellular and Molecular Gastroenterology and Hepatology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.jcmgh.2025.101677","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"https:\/\/doi.org\/10.1016\/j.jcmgh.2025.101638","name":"associatedlink","label":"CrossRef DOI link to the associated document"},{"value":"simple-article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2025 The Authors. Published by Elsevier Inc. on behalf of the AGA Institute.","name":"copyright","label":"Copyright"}],"article-number":"101677"}}