{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,8]],"date-time":"2026-02-08T08:18:51Z","timestamp":1770538731789,"version":"3.49.0"},"reference-count":89,"publisher":"Elsevier BV","issue":"2","license":[{"start":{"date-parts":[[2008,3,1]],"date-time":"2008-03-01T00:00:00Z","timestamp":1204329600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2008,3,1]],"date-time":"2008-03-01T00:00:00Z","timestamp":1204329600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Journal of Cranio-Maxillofacial Surgery"],"published-print":{"date-parts":[[2008,3]]},"DOI":"10.1016\/j.jcms.2007.06.008","type":"journal-article","created":{"date-parts":[[2008,2,1]],"date-time":"2008-02-01T08:46:43Z","timestamp":1201855603000},"page":"95-103","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":178,"title":["\u201cBis-phossy jaws\u201d \u2013 High and low risk factors for bisphosphonate-induced osteonecrosis of the jaw"],"prefix":"10.1016","volume":"36","author":[{"given":"Mario H.","family":"ABU-ID","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Patrick H.","family":"WARNKE","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Joachim","family":"GOTTSCHALK","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ingo","family":"SPRINGER","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"J\u00f6rg","family":"WILTFANG","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yahya","family":"ACIL","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Paul A.J.","family":"RUSSO","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Thomas","family":"KREUSCH","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.jcms.2007.06.008_bib1","article-title":"Bisphosphonate-associated osteonecrosis of the jaw","author":"Abu-Id","year":"2006","journal-title":"Mund Kiefer Gesichtschir"},{"key":"10.1016\/j.jcms.2007.06.008_bib2","doi-asserted-by":"crossref","first-page":"158","DOI":"10.2165\/00002018-199614030-00003","article-title":"Adverse effects of bisphosphonates. A comparative review","volume":"14","author":"Adami","year":"1996","journal-title":"Drug Saf"},{"key":"10.1016\/j.jcms.2007.06.008_bib3","first-page":"210","article-title":"Osteonecrosis of the jaw associated with the long time use of \u2018new\u2019 amino-bisphosphonates by patients with multiple myeloma","volume":"28","author":"Alkemper","year":"2005","journal-title":"Onkologie"},{"key":"10.1016\/j.jcms.2007.06.008_bib4","doi-asserted-by":"crossref","first-page":"1336","DOI":"10.1093\/annonc\/mdl045","article-title":"Could the long-term persistence of low serum calcium levels and high serum parathyroid hormone levels during bisphosphonate treatment predispose metastatic breast cancer patients to undergo osteonecrosis of the jaw?","volume":"17","author":"Ardine","year":"2006","journal-title":"Ann Oncol"},{"key":"10.1016\/j.jcms.2007.06.008_bib5","doi-asserted-by":"crossref","first-page":"945","DOI":"10.1200\/JCO.2005.04.2465","article-title":"Osteonecrosis of the jaw in multiple myeloma patients: clinical features and risk factors","volume":"24","author":"Badros","year":"2006","journal-title":"J Clin Oncol"},{"key":"10.1016\/j.jcms.2007.06.008_bib6","doi-asserted-by":"crossref","first-page":"120","DOI":"10.1111\/j.1600-0714.2004.00269.x","article-title":"Avascular jaw osteonecrosis in association with cancer chemotherapy: series of 10 cases","volume":"34","author":"Bagan","year":"2005","journal-title":"J Oral Pathol Med"},{"key":"10.1016\/j.jcms.2007.06.008_bib7","doi-asserted-by":"crossref","first-page":"8580","DOI":"10.1200\/JCO.2005.02.8670","article-title":"Osteonecrosis of the jaw in cancer after treatment with bisphosphonates: incidence and risk factors","volume":"23","author":"Bamias","year":"2005","journal-title":"J Clin Oncol"},{"key":"10.1016\/j.jcms.2007.06.008_bib8","doi-asserted-by":"crossref","first-page":"821","DOI":"10.1016\/S0140-6736(84)92272-4","article-title":"Focal osteomalacia due to low-dose diphosphonate therapy in Paget's disease","volume":"1","author":"Boyce","year":"1984","journal-title":"Lancet"},{"key":"10.1016\/j.jcms.2007.06.008_bib9","doi-asserted-by":"crossref","first-page":"439","DOI":"10.1532\/IJH97.E0536","article-title":"Jaw osteonecrosis associated with use of bisphosphonates and chemotherapy: paradoxical complication of treatment of bone lesions in multiple myeloma patients","volume":"83","author":"Capalbo","year":"2006","journal-title":"Int J Hematol"},{"key":"10.1016\/j.jcms.2007.06.008_bib10","first-page":"1096","article-title":"Bisphosphonate-associated mandibular osteonecrosis","volume":"27","author":"Carneiro","year":"2006","journal-title":"AJNR Am J Neuroradiol"},{"key":"10.1016\/j.jcms.2007.06.008_bib11","doi-asserted-by":"crossref","first-page":"413","DOI":"10.5694\/j.1326-5377.2005.tb06761.x","article-title":"Bisphosphonates and avascular necrosis of the jaw: a possible association","volume":"182","author":"Carter","year":"2005","journal-title":"Med J Aust"},{"key":"10.1016\/j.jcms.2007.06.008_bib12","doi-asserted-by":"crossref","first-page":"504","DOI":"10.4414\/smw.2006.11431","article-title":"Clinical experiences with bisphosphonate induced osteochemonecrosis of the jaws","volume":"136","author":"Dannemann","year":"2006","journal-title":"Swiss Med Wkly"},{"key":"10.1016\/j.jcms.2007.06.008_bib13","doi-asserted-by":"crossref","DOI":"10.1016\/j.ijom.2006.02.022","article-title":"Bisphosphonate-induced avascular osteonecrosis of the jaws: a clinical report of 11 cases","author":"Dimitrakopoulos","year":"2006","journal-title":"Int J Oral Maxillofac Surg"},{"key":"10.1016\/j.jcms.2007.06.008_bib14","first-page":"968","article-title":"Osteonecrosis of the jaw in patients with multiple myeloma treated with bisphosphonates: evidence of increased risk after treatment with zoledronic acid","volume":"91","author":"Dimopoulos","year":"2006","journal-title":"Haematologica"},{"key":"10.1016\/j.jcms.2007.06.008_bib15","doi-asserted-by":"crossref","first-page":"99","DOI":"10.1056\/NEJM200507073530120","article-title":"Osteonecrosis of the jaw and bisphosphonates","volume":"353","author":"Durie","year":"2005","journal-title":"N Engl J Med"},{"key":"10.1016\/j.jcms.2007.06.008_bib16","doi-asserted-by":"crossref","first-page":"747","DOI":"10.1200\/jco.2004.22.90140.8088","article-title":"Osteonecrosis of the maxilla and mandible in patients treated with bisphosphonates: a retrospective study","volume":"22","author":"Estilo","year":"2004","journal-title":"J Clin Oncol"},{"key":"10.1016\/j.jcms.2007.06.008_bib17","doi-asserted-by":"crossref","first-page":"115","DOI":"10.1097\/01.mlg.0000187398.51857.3c","article-title":"Osteonecrosis of the mandible or maxilla associated with the use of new generation bisphosphonates","volume":"116","author":"Farrugia","year":"2006","journal-title":"Laryngoscope"},{"key":"10.1016\/j.jcms.2007.06.008_bib18","doi-asserted-by":"crossref","first-page":"35","DOI":"10.1016\/S0378-5122(98)00050-4","article-title":"Placebo-controlled multicenter study of oral alendronate in postmenopausal osteoporotic women. FOSIT-Study-Group","volume":"31","author":"Felsenberg","year":"1998","journal-title":"Maturitas"},{"key":"10.1016\/j.jcms.2007.06.008_bib19","doi-asserted-by":"crossref","first-page":"1123","DOI":"10.1111\/j.1600-051X.2005.00842.x","article-title":"Osteonecrosis of the jaws in periodontal patients with a history of bisphosphonates treatment","volume":"32","author":"Ficarra","year":"2005","journal-title":"J Clin Periodontol"},{"key":"10.1016\/j.jcms.2007.06.008_bib20","first-page":"6538","article-title":"Bisphosphonates inhibit angiogenesis in vitro and testosterone-stimulated vascular regrowth in the ventral prostate in castrated rats","volume":"62","author":"Fournier","year":"2002","journal-title":"Cancer Res"},{"key":"10.1016\/j.jcms.2007.06.008_bib21","doi-asserted-by":"crossref","first-page":"514","DOI":"10.1034\/j.1600-0714.2000.291006.x","article-title":"Alendronate-related oral mucosa ulcerations","volume":"29","author":"Gonzalez-Moles","year":"2000","journal-title":"J Oral Pathol Med"},{"key":"10.1016\/j.jcms.2007.06.008_bib22","first-page":"44","article-title":"Bisphosphonate-associated osteonecrosis of the jaws and endodontic treatment: two case reports","volume":"55","author":"Goodell","year":"2006","journal-title":"J Mass Dent Soc"},{"key":"10.1016\/j.jcms.2007.06.008_bib23","doi-asserted-by":"crossref","first-page":"1571","DOI":"10.1016\/j.joms.2006.05.041","article-title":"Persisting alveolar sockets-a radiologic symptom of BP-ONJ?","volume":"64","author":"Groetz","year":"2006","journal-title":"J Oral Maxillofac Surg"},{"key":"10.1016\/j.jcms.2007.06.008_bib24","first-page":"4","article-title":"Association of osteonecrosis of the jaws and bisphosphonate pharmacotherapy: dental implications","volume":"102","author":"Hay","year":"2006","journal-title":"N Z Dent J"},{"key":"10.1016\/j.jcms.2007.06.008_bib25","doi-asserted-by":"crossref","first-page":"682","DOI":"10.1016\/j.joms.2005.01.010","article-title":"Bisphosphonate osteochemonecrosis (bis-phossy jaw): is this phossy jaw of the 21st century?","volume":"63","author":"Hellstein","year":"2005","journal-title":"J Oral Maxillofac Surg"},{"key":"10.1016\/j.jcms.2007.06.008_bib26","doi-asserted-by":"crossref","first-page":"483","DOI":"10.1001\/archpedi.1926.04130100003001","article-title":"The value of elementary phosphorus in rickets","volume":"32","author":"Hess","year":"1926","journal-title":"Am J Dis Child"},{"key":"10.1016\/j.jcms.2007.06.008_bib27","doi-asserted-by":"crossref","first-page":"233","DOI":"10.1007\/s10006-005-0624-6","article-title":"Osteonecrosis of the jaws as a possible adverse effect of the use of bisphosphonates","volume":"9","author":"Hoefert","year":"2005","journal-title":"Mund Kiefer Gesichtschir"},{"key":"10.1016\/j.jcms.2007.06.008_bib28","doi-asserted-by":"crossref","first-page":"8528","DOI":"10.1200\/jco.2006.24.18_suppl.8528","article-title":"Osteonecrosis of the jaw in patients receiving intravenous bisphosphonate therapy","volume":"24","author":"Hoff","year":"2006","journal-title":"J Clin Oncol"},{"key":"10.1016\/j.jcms.2007.06.008_bib29","first-page":"83","article-title":"Phosphorus necrosis of the jaw: a present-day study","volume":"19","author":"Hughes","year":"1962","journal-title":"Br J Ind Med"},{"key":"10.1016\/j.jcms.2007.06.008_bib30","doi-asserted-by":"crossref","first-page":"1100","DOI":"10.4065\/81.8.1100","article-title":"Primary surgical therapy for osteonecrosis of the jaw secondary to bisphosphonate therapy","volume":"81","author":"Kademani","year":"2006","journal-title":"Mayo Clin Proc"},{"key":"10.1016\/j.jcms.2007.06.008_bib31","first-page":"36","article-title":"Die Behandlung der Rachitis mit Phosphor","volume":"7","author":"Kassowitz","year":"1884","journal-title":"Ztschrft f klin Med"},{"key":"10.1016\/j.jcms.2007.06.008_bib32","doi-asserted-by":"crossref","first-page":"831","DOI":"10.1097\/01.don.0000186481.96169.cd","article-title":"Endodontic implications of bisphosphonate-associated osteonecrosis of the jaws: a report of three cases","volume":"31","author":"Katz","year":"2005","journal-title":"J Endod"},{"key":"10.1016\/j.jcms.2007.06.008_bib33","doi-asserted-by":"crossref","first-page":"1172","DOI":"10.1210\/jc.2006-2036","article-title":"Possible association between diabetes and bisphosphonate-related jaw osteonecrosis","volume":"92","author":"Khamaisi","year":"2007","journal-title":"J Clin Endocrinol Metab"},{"key":"10.1016\/j.jcms.2007.06.008_bib34","doi-asserted-by":"crossref","first-page":"999","DOI":"10.1359\/JBMR.040126","article-title":"Suppressed bone turnover by long-term bisphosphonate treatment accumulates microdamage but maintains intrinsic material properties in cortical bone of dog rib","volume":"19","author":"Komatsubara","year":"2004","journal-title":"J Bone Miner Res"},{"key":"10.1016\/j.jcms.2007.06.008_bib35","first-page":"A93","article-title":"Klinischer Verlauf und Strategien in der Behandlung der Bisphosphonat-induzierten Osteonekrose der Kiefer","volume":"60","author":"Krimmel","year":"2005","journal-title":"Dtsch Zahn\u00e4rztl Z"},{"key":"10.1016\/j.jcms.2007.06.008_bib36","doi-asserted-by":"crossref","first-page":"1113","DOI":"10.1902\/jop.2005.76.7.1113","article-title":"Bisphosphonate therapy improves the outcome of conventional periodontal treatment: results of a 12-month, randomized, placebo-controlled study","volume":"76","author":"Lane","year":"2005","journal-title":"J Periodontol"},{"key":"10.1016\/j.jcms.2007.06.008_bib37","doi-asserted-by":"crossref","first-page":"14","DOI":"10.1016\/j.tripleo.2005.10.045","article-title":"Bisphosphonate-associated osteonecrosis of the jaws. Report of a case and literature review","volume":"102","author":"Leite","year":"2006","journal-title":"Oral Surg Oral Med Oral Pathol Oral Radiol Endod"},{"key":"10.1016\/j.jcms.2007.06.008_bib38","doi-asserted-by":"crossref","first-page":"395","DOI":"10.1016\/j.jcms.2005.07.007","article-title":"Does avascular necrosis of the jaws in cancer patients only occur following treatment with bisphosphonates?","volume":"33","author":"Lenz","year":"2005","journal-title":"J\u00a0Craniomaxillofac Surg"},{"key":"10.1016\/j.jcms.2007.06.008_bib39","doi-asserted-by":"crossref","first-page":"440","DOI":"10.1016\/j.amjmed.2004.04.015","article-title":"Severe osteomyelitis of the jaw in long-term survivors of multiple myeloma: a new clinical entity","volume":"117","author":"Lugassy","year":"2004","journal-title":"Am J Med"},{"key":"10.1016\/j.jcms.2007.06.008_bib40","doi-asserted-by":"crossref","first-page":"8271","DOI":"10.1200\/jco.2005.23.16_suppl.8271","article-title":"Ten cases of osteonecrosis of the jaws following a treatment by bisphosphonates within the framework of metastasis of breast cancer and multiple myeloma: experience in summer 2004 of a single center","volume":"23","author":"Maerevoet","year":"2004","journal-title":"J Clin Oncol"},{"key":"10.1016\/j.jcms.2007.06.008_bib41","doi-asserted-by":"crossref","first-page":"1669","DOI":"10.14219\/jada.archive.2005.0109","article-title":"Bisphosphonate-associated osteonecrosis of the jaws: a review of current knowledge","volume":"136","author":"Markiewicz","year":"2005","journal-title":"J Am Dent Assoc"},{"key":"10.1016\/j.jcms.2007.06.008_bib42","first-page":"26","article-title":"Recent reports link bisphosphonates use to osteonecrosis","volume":"18","author":"Marunick","year":"2006","journal-title":"Todays FDA"},{"key":"10.1016\/j.jcms.2007.06.008_bib43","doi-asserted-by":"crossref","first-page":"1115","DOI":"10.1016\/S0278-2391(03)00720-1","article-title":"Pamidronate (Aredia) and zoledronate (Zometa) induced avascular necrosis of the jaws: a growing epidemic","volume":"61","author":"Marx","year":"2003","journal-title":"J Oral Maxillofac Surg"},{"key":"10.1016\/j.jcms.2007.06.008_bib44","doi-asserted-by":"crossref","first-page":"1567","DOI":"10.1016\/j.joms.2005.07.010","article-title":"Bisphosphonate-induced exposed bone (osteonecrosis\/osteopetrosis) of the jaws: risk factors, recognition, prevention, and treatment","volume":"63","author":"Marx","year":"2005","journal-title":"J Oral Maxillofac Surg"},{"key":"10.1016\/j.jcms.2007.06.008_bib45","doi-asserted-by":"crossref","first-page":"415","DOI":"10.1016\/j.joms.2006.10.061","article-title":"Nature and frequency of bisphosphonate-associated osteonecrosis of the jaws in Australia","volume":"65","author":"Mavrokokki","year":"2007","journal-title":"J\u00a0Oral Maxillofac Surg"},{"key":"10.1016\/j.jcms.2007.06.008_bib46","doi-asserted-by":"crossref","first-page":"1675","DOI":"10.14219\/jada.archive.2005.0110","article-title":"Osteonecrosis of the jaws in patients with a history of receiving bisphosphonate therapy: strategies for prevention and early recognition","volume":"136","author":"Melo","year":"2005","journal-title":"J Am Dent Assoc"},{"key":"10.1016\/j.jcms.2007.06.008_bib47","first-page":"111","article-title":"Osteonecrosis of the maxilla in a patient with a history of bisphosphonate therapy","volume":"71","author":"Melo","year":"2005","journal-title":"J Can Dent Assoc"},{"key":"10.1016\/j.jcms.2007.06.008_bib48","doi-asserted-by":"crossref","first-page":"613","DOI":"10.1111\/j.1600-0714.2005.00351.x","article-title":"Jaw bone necrosis without previous dental extractions associated with the use of bisphosphonates (pamidronate and zoledronate): a four-case report","volume":"34","author":"Merigo","year":"2005","journal-title":"J Oral Pathol Med"},{"key":"10.1016\/j.jcms.2007.06.008_bib49","doi-asserted-by":"crossref","first-page":"1658","DOI":"10.14219\/jada.archive.2005.0108","article-title":"Managing the care of patients with bisphosphonate-associated osteonecrosis: an American Academy of Oral Medicine position paper","volume":"136","author":"Migliorati","year":"2005","journal-title":"J Am Dent Assoc"},{"key":"10.1016\/j.jcms.2007.06.008_bib50","doi-asserted-by":"crossref","first-page":"83","DOI":"10.1002\/cncr.21130","article-title":"Bisphosphonate-associated osteonecrosis of mandibular and maxillary bone: an emerging oral complication of supportive cancer therapy","volume":"104","author":"Migliorati","year":"2005","journal-title":"Cancer"},{"key":"10.1016\/j.jcms.2007.06.008_bib51","doi-asserted-by":"crossref","first-page":"508","DOI":"10.1016\/S1470-2045(06)70726-4","article-title":"Bisphosphonate-associated osteonecrosis: a long-term complication of bisphosphonate treatment","volume":"7","author":"Migliorati","year":"2006","journal-title":"Lancet Oncol"},{"key":"10.1016\/j.jcms.2007.06.008_bib52","doi-asserted-by":"crossref","first-page":"1475","DOI":"10.1200\/JCO.2005.01.7756","article-title":"Case 2. Osteonecrosis of the jaws associated with bisphosphonate therapy","volume":"24","author":"Mignogna","year":"2006","journal-title":"J Clin Oncol"},{"issue":"Suppl. 3","key":"10.1016\/j.jcms.2007.06.008_bib53","article-title":"Bisphosphonates and jaw osteonecrosis: experience with ibandronate","volume":"372","author":"Morris","year":"2005","journal-title":"Eur J Cancer"},{"key":"10.1016\/j.jcms.2007.06.008_bib54","doi-asserted-by":"crossref","first-page":"1115","DOI":"10.14219\/jada.archive.2006.0350","article-title":"Osteonecrosis of the jaw and oral bisphosphonate treatment","volume":"137","author":"Nase","year":"2006","journal-title":"J Am Dent Assoc"},{"key":"10.1016\/j.jcms.2007.06.008_bib55","doi-asserted-by":"crossref","first-page":"658","DOI":"10.1016\/j.urology.2005.03.028","article-title":"Osteonecrosis of jaw in patient with hormone-refractory prostate cancer treated with zoledronic acid","volume":"66","author":"Olson","year":"2005","journal-title":"Urology"},{"key":"10.1016\/j.jcms.2007.06.008_bib56","doi-asserted-by":"crossref","first-page":"216","DOI":"10.1080\/02841860500341173","article-title":"Jaw complications in breast and prostate cancer patients treated with zoledronic acid","volume":"45","author":"Ortega","year":"2006","journal-title":"Acta Oncol"},{"key":"10.1016\/j.jcms.2007.06.008_bib57","first-page":"E76","article-title":"Osteonecrosis of the jaws and bisphosphonates. Report of three cases","volume":"11","author":"Pastor-Zuazaga","year":"2006","journal-title":"Med Oral Patol Oral Cir Bucal"},{"key":"10.1016\/j.jcms.2007.06.008_bib58","doi-asserted-by":"crossref","first-page":"739","DOI":"10.1016\/0030-4220(93)90433-5","article-title":"Lingual mandibular sequestration and ulceration","volume":"75","author":"Peters","year":"1993","journal-title":"Oral Surg Oral Med Oral Pathol"},{"key":"10.1016\/j.jcms.2007.06.008_bib59","article-title":"Osteonecrosis of the jaws by long term therapy with bisphosphonates","author":"Piesold","year":"2006","journal-title":"Mund Kiefer Gesichtschir"},{"key":"10.1016\/j.jcms.2007.06.008_bib60","doi-asserted-by":"crossref","first-page":"365","DOI":"10.1111\/j.1601-0825.2005.01130.x","article-title":"Oral avascular bone necrosis associated with chemotherapy and biphosphonate therapy","volume":"11","author":"Pires","year":"2005","journal-title":"Oral Dis"},{"key":"10.1016\/j.jcms.2007.06.008_bib61","doi-asserted-by":"crossref","first-page":"114","DOI":"10.1111\/j.1365-2141.2005.05833.x","article-title":"Bisphosphonate-associated osteonecrosis of the auditory canal","volume":"132","author":"Polizzotto","year":"2006","journal-title":"Br J Haematol"},{"key":"10.1016\/j.jcms.2007.06.008_bib62","doi-asserted-by":"crossref","first-page":"56","DOI":"10.1080\/10428190600977690","article-title":"Bisphosphonate-associated osteonecrosis of the jaw: a review of 35 cases and an evaluation of its frequency in multiple myeloma patients","volume":"48","author":"Pozzi","year":"2007","journal-title":"Leuk Lymphoma"},{"key":"10.1016\/j.jcms.2007.06.008_bib63","doi-asserted-by":"crossref","first-page":"417","DOI":"10.5694\/j.1326-5377.2005.tb06762.x","article-title":"Bisphosphonates and osteonecrosis of the jaw","volume":"182","author":"Purcell","year":"2005","journal-title":"Med J Aust"},{"key":"10.1016\/j.jcms.2007.06.008_bib64","doi-asserted-by":"crossref","first-page":"2613","DOI":"10.1002\/cncr.20308","article-title":"Long-term efficacy and safety of zoledronic acid in the treatment of skeletal metastases in patients with nonsmall cell lung carcinoma and other solid tumors: a randomized, phase III, double-blind, placebo-controlled trial","volume":"100","author":"Rosen","year":"2004","journal-title":"Cancer"},{"key":"10.1016\/j.jcms.2007.06.008_bib65","doi-asserted-by":"crossref","first-page":"433","DOI":"10.1016\/j.tripleo.2006.06.004","article-title":"Bisphosphonate-related osteonecrosis of the jaw: background and guidelines for diagnosis, staging and management","volume":"102","author":"Ruggiero","year":"2006","journal-title":"Oral Surg Oral Med Oral Pathol Oral Radiol Endod"},{"key":"10.1016\/j.jcms.2007.06.008_bib66","doi-asserted-by":"crossref","first-page":"527","DOI":"10.1016\/j.joms.2004.02.004","article-title":"Osteonecrosis of the jaws associated with the use of bisphosphonates: a review of 63 cases","volume":"62","author":"Ruggiero","year":"2004","journal-title":"J Oral Maxillofac Surg"},{"key":"10.1016\/j.jcms.2007.06.008_bib67","first-page":"679","article-title":"Kieferosteomyelitis nach Therapie systemischer osteolytischer Prozesse mit Bisphosphonaten","volume":"56","author":"R\u00fchlmann","year":"2005","journal-title":"Quintessenz"},{"key":"10.1016\/j.jcms.2007.06.008_bib68","doi-asserted-by":"crossref","first-page":"1207","DOI":"10.1093\/annonc\/mdi206","article-title":"Jaw avascular bone necrosis associated with long-term use of biphosphonates","volume":"16","author":"Sanna","year":"2005","journal-title":"Ann Oncol"},{"key":"10.1016\/j.jcms.2007.06.008_bib69","doi-asserted-by":"crossref","first-page":"759","DOI":"10.1097\/01.don.0000182737.09980.2c","article-title":"Bisphosphonate-associated osteonecrosis of the jaws and endodontic treatment: two case reports","volume":"31","author":"Sarathy","year":"2005","journal-title":"J Endod"},{"key":"10.1016\/j.jcms.2007.06.008_bib70","doi-asserted-by":"crossref","first-page":"239","DOI":"10.1007\/s10006-005-0616-6","article-title":"Bisphosphonates and osteonecrosis of the jaw","volume":"9","author":"Schirmer","year":"2005","journal-title":"Mund Kiefer Gesichtschir"},{"key":"10.1016\/j.jcms.2007.06.008_bib71","series-title":"Arzneiverordnungsreport 2005","first-page":"755","article-title":"Mineralstoffpr\u00e4parate und Osteoporosemittel","author":"Schwabe","year":"2005"},{"key":"10.1016\/j.jcms.2007.06.008_bib72","doi-asserted-by":"crossref","first-page":"251","DOI":"10.1002\/hed.2890040313","article-title":"Osteonecrosis of the jaws: a complication of cancer chemotherapy","volume":"4","author":"Schwartz","year":"1982","journal-title":"Head Neck Surg"},{"key":"10.1016\/j.jcms.2007.06.008_bib73","first-page":"536","article-title":"Avascular necrosis of the jaw bone after bisphosphonate therapy","volume":"144","author":"Shlomi","year":"2005","journal-title":"Harefuah"},{"key":"10.1016\/j.jcms.2007.06.008_bib74","doi-asserted-by":"crossref","first-page":"738","DOI":"10.1902\/jop.2006.050187","article-title":"Oral post-surgical complications following the administration of bisphosphonates given for osteopenia related to malignancy","volume":"77","author":"Soileau","year":"2006","journal-title":"J Periodontol"},{"key":"10.1016\/j.jcms.2007.06.008_bib75","doi-asserted-by":"crossref","first-page":"468","DOI":"10.14219\/jada.archive.1978.0304","article-title":"Oral complications in patients receiving treatment for malignancies other than of the head and neck","volume":"97","author":"Sonis","year":"1978","journal-title":"J Am Dent Assoc"},{"key":"10.1016\/j.jcms.2007.06.008_bib76","doi-asserted-by":"crossref","first-page":"1238","DOI":"10.1016\/j.joms.2003.09.001","article-title":"Avascular necrosis of the jaws: risk factors in metastatic cancer patients","volume":"61","author":"Tarassoff","year":"2003","journal-title":"J Oral Maxillofac Surg"},{"key":"10.1016\/j.jcms.2007.06.008_bib77","doi-asserted-by":"crossref","first-page":"51","DOI":"10.1385\/MO:23:1:51","article-title":"Jaw complications associated with bisphosphonate use in patients with plasma cell dyscrasias","volume":"23","author":"Thakkar","year":"2006","journal-title":"Med Oncol"},{"key":"10.1016\/j.jcms.2007.06.008_bib78","first-page":"215","article-title":"Bisphosphonate-induced osteonecrosis of the jaws: a case report and literature review","volume":"54","author":"Tsai","year":"2006","journal-title":"Gen Dent"},{"key":"10.1016\/j.jcms.2007.06.008_bib79","doi-asserted-by":"crossref","first-page":"738","DOI":"10.1111\/j.1365-2141.2005.05382.x","article-title":"Osteonecrosis of the jaw associated with zoledronate therapy in a patient with multiple myeloma","volume":"128","author":"Vannucchi","year":"2005","journal-title":"Br J Haematol"},{"key":"10.1016\/j.jcms.2007.06.008_bib80","doi-asserted-by":"crossref","first-page":"355","DOI":"10.1188\/05.CJON.355-357","article-title":"Exposed bone in oral cavities","volume":"9","author":"Viale","year":"2005","journal-title":"Clin J Oncol Nurs"},{"key":"10.1016\/j.jcms.2007.06.008_bib81","article-title":"Prevalence of bisphosphonate associated osteonecrosis of the jaw within the field of osteonecrosis","author":"Walter","year":"2006","journal-title":"Support Care Cancer"},{"key":"10.1016\/j.jcms.2007.06.008_bib82","doi-asserted-by":"crossref","first-page":"1104","DOI":"10.1016\/S0278-2391(03)00328-8","article-title":"Osteonecrosis of the jaws associated with cancer chemotherapy","volume":"61","author":"Wang","year":"2003","journal-title":"J Oral Maxillofac Surg"},{"key":"10.1016\/j.jcms.2007.06.008_bib83","doi-asserted-by":"crossref","first-page":"11","DOI":"10.1007\/BF01937197","article-title":"Der Einfluss des Phosphors auf den Organismus","volume":"55","author":"Wegner","year":"1872","journal-title":"Arch Path Anat (Virchows Arch)"},{"key":"10.1016\/j.jcms.2007.06.008_bib84","doi-asserted-by":"crossref","first-page":"15","DOI":"10.1002\/ar.1091770103","article-title":"Pathogenesis of abnormal remodeling of bones: effects of yellow phosphorus in the growing rat","volume":"177","author":"Whalen","year":"1973","journal-title":"Anat Rec"},{"key":"10.1016\/j.jcms.2007.06.008_bib85","doi-asserted-by":"crossref","first-page":"457","DOI":"10.1056\/NEJMoa023110","article-title":"Bisphosphonate-induced osteopetrosis","volume":"349","author":"Whyte","year":"2003","journal-title":"N Engl J Med"},{"key":"10.1016\/j.jcms.2007.06.008_bib86","doi-asserted-by":"crossref","first-page":"473","DOI":"10.1007\/s00508-006-0644-8","article-title":"Osteonecrosis of the jaws and bisphosphonate treatment in cancer patients","volume":"118","author":"Wutzl","year":"2006","journal-title":"Wien Klin Wochenschr"},{"key":"10.1016\/j.jcms.2007.06.008_bib87","doi-asserted-by":"crossref","first-page":"221","DOI":"10.1615\/CritRevEukaryotGeneExpr.v13.i24.140","article-title":"Role of apoptosis in glucocorticoid-induced osteoporosis and osteonecrosis","volume":"13","author":"Zalavras","year":"2003","journal-title":"Crit Rev Eukaryot Gene Expr"},{"key":"10.1016\/j.jcms.2007.06.008_bib88","doi-asserted-by":"crossref","first-page":"73","DOI":"10.1002\/ajh.20481","article-title":"Osteonecrosis of the jaw associated with pamidronate therapy","volume":"81","author":"Zarychanski","year":"2006","journal-title":"Am J Hematol"},{"key":"10.1016\/j.jcms.2007.06.008_bib89","doi-asserted-by":"crossref","first-page":"620","DOI":"10.1111\/j.1365-2141.2006.06230.x","article-title":"Incidence, risk factors and management of osteonecrosis of the jaw in patients with multiple myeloma: a single-centre experience in 303 patients","volume":"134","author":"Zervas","year":"2006","journal-title":"Br J Haematol"}],"container-title":["Journal of Cranio-Maxillofacial Surgery"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1010518207001308?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1010518207001308?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,19]],"date-time":"2025-10-19T14:23:19Z","timestamp":1760883799000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1010518207001308"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2008,3]]},"references-count":89,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2008,3]]}},"alternative-id":["S1010518207001308"],"URL":"https:\/\/doi.org\/10.1016\/j.jcms.2007.06.008","relation":{},"ISSN":["1010-5182"],"issn-type":[{"value":"1010-5182","type":"print"}],"subject":[],"published":{"date-parts":[[2008,3]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"\u201cBis-phossy jaws\u201d \u2013 High and low risk factors for bisphosphonate-induced osteonecrosis of the jaw","name":"articletitle","label":"Article Title"},{"value":"Journal of Cranio-Maxillofacial Surgery","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.jcms.2007.06.008","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2007 European Association for Cranio-Maxillofacial Surgery. Published by Elsevier Ltd. All rights reserved.","name":"copyright","label":"Copyright"}]}}