{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,26]],"date-time":"2026-10-26T18:59:11Z","timestamp":1793041151270,"version":"4.5.0"},"reference-count":35,"publisher":"Elsevier BV","issue":"4","license":[{"start":{"date-parts":[[2017,4,1]],"date-time":"2017-04-01T00:00:00Z","timestamp":1491004800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2017,4,1]],"date-time":"2017-04-01T00:00:00Z","timestamp":1491004800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Journal of Cranio-Maxillofacial Surgery"],"published-print":{"date-parts":[[2017,4]]},"DOI":"10.1016\/j.jcms.2017.01.008","type":"journal-article","created":{"date-parts":[[2017,1,25]],"date-time":"2017-01-25T12:48:11Z","timestamp":1485348491000},"page":"579-584","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":12,"title":["Elective neck dissection in unilateral carcinomas of the tongue: Unilateral versus bilateral approach"],"prefix":"10.1016","volume":"45","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-0572-0870","authenticated-orcid":false,"given":"Christopher-Philipp","family":"Nobis","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sven","family":"Otto","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tamara","family":"Grigorieva","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mohamed","family":"Alnaqbi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Matthias","family":"Troeltzsch","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jakob","family":"Sch\u00f6pe","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4558-4041","authenticated-orcid":false,"given":"Stefan","family":"Wagenpfeil","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michael","family":"Ehrenfeld","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Klaus-Dietrich","family":"Wolff","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marco Rainer","family":"Kesting","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.jcms.2017.01.008_bib1","doi-asserted-by":"crossref","first-page":"35","DOI":"10.1016\/j.cca.2014.04.027","article-title":"Expression of vascular endothelial growth factor (VEGF) in patients with oral squamous cell carcinoma and its clinical significance","volume":"436","author":"Aggarwal","year":"2014","journal-title":"Clin Chim Acta"},{"key":"10.1016\/j.jcms.2017.01.008_bib2","doi-asserted-by":"crossref","first-page":"1131","DOI":"10.1007\/s00405-006-0128-5","article-title":"Prevalence and localization of nodal metastases in squamous cell carcinoma of the oral cavity: role and extension of neck dissection","volume":"263","author":"De Zinis","year":"2006","journal-title":"Eur Arch Oto-Rhino-Laryngol"},{"key":"10.1016\/j.jcms.2017.01.008_bib3","doi-asserted-by":"crossref","first-page":"268","DOI":"10.1017\/S0022215114000267","article-title":"Patterns of cervical lymph node metastases in oral tongue squamous cell carcinoma: implications for elective and therapeutic neck dissection","volume":"128","author":"Dogan","year":"2014","journal-title":"J\u00a0Laryngol Otol"},{"key":"10.1016\/j.jcms.2017.01.008_bib4","doi-asserted-by":"crossref","first-page":"320","DOI":"10.1016\/j.oraloncology.2011.03.009","article-title":"A\u00a0meta-analysis of the randomized controlled trials on elective neck dissection versus therapeutic neck dissection in oral cavity cancers with clinically node-negative neck","volume":"47","author":"Fasunla","year":"2011","journal-title":"Oral Oncol"},{"key":"10.1016\/j.jcms.2017.01.008_bib5","doi-asserted-by":"crossref","first-page":"360","DOI":"10.1016\/S0002-9610(05)80333-2","article-title":"Improved survival in the treatment of squamous carcinoma of the oral tongue","volume":"166","author":"Franceschi","year":"1993","journal-title":"Am J Surg"},{"key":"10.1016\/j.jcms.2017.01.008_bib6","doi-asserted-by":"crossref","first-page":"67","DOI":"10.1002\/hed.2890080202","article-title":"Prognostic significance of lymphatic spread in head and neck carcinomas: therapeutic implications","volume":"8","author":"Grandi","year":"1985","journal-title":"Head Neck Surg"},{"key":"10.1016\/j.jcms.2017.01.008_bib7","doi-asserted-by":"crossref","first-page":"517","DOI":"10.1002\/(SICI)1097-0347(199909)21:6<517::AID-HED4>3.0.CO;2-C","article-title":"Improved survival for patients with clinically T1\/T2, N0 tongue tumors undergoing a prophylactic neck dissection","volume":"21","author":"Haddadin","year":"1999","journal-title":"Head Neck"},{"key":"10.1016\/j.jcms.2017.01.008_bib8","doi-asserted-by":"crossref","first-page":"1066","DOI":"10.1002\/cncr.23278","article-title":"Neck treatment of patients with early stage oral tongue cancer: comparison between observation, supraomohyoid dissection, and extended dissection","volume":"112","author":"Huang","year":"2008","journal-title":"Cancer"},{"key":"10.1016\/j.jcms.2017.01.008_bib9","doi-asserted-by":"crossref","first-page":"96","DOI":"10.1016\/j.oraloncology.2005.06.018","article-title":"Elective neck treatment versus observation in patients with T1\/T2 N0 squamous cell carcinoma of oral tongue","volume":"42","author":"Keski-Santti","year":"2006","journal-title":"Oral Oncol"},{"key":"10.1016\/j.jcms.2017.01.008_bib10","doi-asserted-by":"crossref","first-page":"1088","DOI":"10.1097\/00005537-200106000-00029","article-title":"Is dissection of level IV necessary in patients with T1-T3 N0 tongue cancer?","volume":"111","author":"Khafif","year":"2001","journal-title":"Laryngoscope"},{"key":"10.1016\/j.jcms.2017.01.008_bib11","doi-asserted-by":"crossref","first-page":"896","DOI":"10.1002\/hed.20423","article-title":"Management of contralateral N0 neck in oral cavity squamous cell carcinoma","volume":"28","author":"Koo","year":"2006","journal-title":"Head Neck"},{"key":"10.1016\/j.jcms.2017.01.008_bib12","doi-asserted-by":"crossref","first-page":"104","DOI":"10.1002\/(SICI)1097-0347(199903)21:2<104::AID-HED2>3.0.CO;2-L","article-title":"Factors influencing contralateral lymph node metastasis from oral carcinoma","volume":"21","author":"Kowalski","year":"1999","journal-title":"Head Neck"},{"key":"10.1016\/j.jcms.2017.01.008_bib13","doi-asserted-by":"crossref","first-page":"485","DOI":"10.1038\/modpathol.3800295","article-title":"Potential autocrine function of vascular endothelial growth factor in head and neck cancer via vascular endothelial growth factor receptor-2","volume":"18","author":"Kyzas","year":"2005","journal-title":"Mod Pathol"},{"key":"10.1016\/j.jcms.2017.01.008_bib14","doi-asserted-by":"crossref","first-page":"610","DOI":"10.1016\/j.ijom.2007.01.009","article-title":"Unilateral, clinically T2N0, squamous cell carcinoma of the tongue: surgical outcome analysis","volume":"36","author":"Lim","year":"2007","journal-title":"Int J Oral Maxillofac Surg"},{"key":"10.1016\/j.jcms.2017.01.008_bib15","doi-asserted-by":"crossref","first-page":"461","DOI":"10.1097\/01.mlg.0000195366.91395.9b","article-title":"Treatment of contralateral N0 neck in early squamous cell carcinoma of the oral tongue: elective neck dissection versus observation","volume":"116","author":"Lim","year":"2006","journal-title":"Laryngoscope"},{"key":"10.1016\/j.jcms.2017.01.008_bib16","doi-asserted-by":"crossref","first-page":"75","DOI":"10.1111\/j.1601-0825.2000.tb00105.x","article-title":"The epidemiology of tongue cancer: a review of global incidence","volume":"6","author":"Moore","year":"2000","journal-title":"Oral Dis"},{"key":"10.1016\/j.jcms.2017.01.008_bib17","doi-asserted-by":"crossref","first-page":"1260","DOI":"10.1002\/hed.21622","article-title":"Comparison of morbidity between sentinel node biopsy and elective neck dissection for treatment of the n0 neck in patients with oral squamous cell carcinoma","volume":"33","author":"Murer","year":"2011","journal-title":"Head Neck"},{"key":"10.1016\/j.jcms.2017.01.008_bib18","doi-asserted-by":"crossref","first-page":"3528","DOI":"10.1245\/s10434-011-2207-0","article-title":"Sentinel lymph node biopsy for T1\/T2 oral cavity squamous cell carcinoma\u2500a prospective case series","volume":"19","author":"Pezier","year":"2012","journal-title":"Ann Surg Oncol"},{"key":"10.1016\/j.jcms.2017.01.008_bib19","doi-asserted-by":"crossref","first-page":"897","DOI":"10.1016\/j.joms.2014.12.030","article-title":"Vascular endothelial growth factor receptor isoforms: are they present in oral squamous cell carcinoma?","volume":"73","author":"Pianka","year":"2015","journal-title":"J\u00a0Oral Maxillofac Surg"},{"key":"10.1016\/j.jcms.2017.01.008_bib20","doi-asserted-by":"crossref","first-page":"164","DOI":"10.1054\/bjom.1999.0031","article-title":"Squamous carcinoma of the tongue: review","volume":"37","author":"Prince","year":"1999","journal-title":"Br J Oral Maxillofac Surg"},{"key":"10.1016\/j.jcms.2017.01.008_bib21","series-title":"R: A language and environment for statistical computing","author":"R-Core-Team","year":"2015"},{"key":"10.1016\/j.jcms.2017.01.008_bib22","doi-asserted-by":"crossref","first-page":"751","DOI":"10.1001\/archotol.128.7.751","article-title":"Neck dissection classification update: revisions proposed by the American Head and Neck Society and the American Academy of Otolaryngology-Head and Neck Surgery","volume":"128","author":"Robbins","year":"2002","journal-title":"Arch Otolaryngol Head Neck Surg"},{"key":"10.1016\/j.jcms.2017.01.008_bib23","series-title":"Krebs in Deutschland 2011\/2012. Robert Koch-Institut und die Gesellschaft der epidemiologischen Krebsregister in Deutschland e.V. Berlin 10","first-page":"26","author":"Robert Koch Institut","year":"2015"},{"key":"10.1016\/j.jcms.2017.01.008_bib24","doi-asserted-by":"crossref","first-page":"1221","DOI":"10.1007\/s00784-013-1070-8","article-title":"Cervical metastases of squamous cell carcinoma of the maxilla: a retrospective study of 25 years","volume":"18","author":"Sagheb","year":"2014","journal-title":"Clin Oral Invest"},{"key":"10.1016\/j.jcms.2017.01.008_bib25","doi-asserted-by":"crossref","first-page":"645","DOI":"10.1007\/s10555-007-9082-y","article-title":"Metastasis of squamous cell carcinoma of the oral tongue","volume":"26","author":"Sano","year":"2007","journal-title":"Cancer Metastasis Rev"},{"key":"10.1016\/j.jcms.2017.01.008_bib26","doi-asserted-by":"crossref","first-page":"503","DOI":"10.1002\/hed.21001","article-title":"Function, postoperative morbidity, and quality of life after cervical sentinel node biopsy and after selective neck dissection","volume":"31","author":"Schiefke","year":"2009","journal-title":"Head Neck"},{"key":"10.1016\/j.jcms.2017.01.008_bib27","doi-asserted-by":"crossref","first-page":"557","DOI":"10.1288\/00005537-198004000-00001","article-title":"The prognostic significance of metastatic cervical lymph nodes","volume":"90","author":"Schuller","year":"1980","journal-title":"Laryngoscope"},{"key":"10.1016\/j.jcms.2017.01.008_bib28","doi-asserted-by":"crossref","first-page":"109","DOI":"10.1002\/1097-0142(19900701)66:1<109::AID-CNCR2820660120>3.0.CO;2-A","article-title":"The patterns of cervical lymph node metastases from squamous carcinoma of the oral cavity","volume":"66","author":"Shah","year":"1990","journal-title":"Cancer"},{"key":"10.1016\/j.jcms.2017.01.008_bib29","doi-asserted-by":"crossref","first-page":"14","DOI":"10.1002\/ssu.2980070105","article-title":"Elective treatment of the neck in cancer of the oral tongue","volume":"7","author":"Silver","year":"1991","journal-title":"Semin Surg Oncol"},{"key":"10.1016\/j.jcms.2017.01.008_bib30","first-page":"957","article-title":"Combined effect of tobacco and alcohol on laryngeal cancer risk: a case-control study","volume":"13","author":"Talamini","year":"2002","journal-title":"Cancer Causes Control"},{"key":"10.1016\/j.jcms.2017.01.008_bib31","series-title":"A\u00a0package for survival analysis in S","author":"Therneau","year":"2015"},{"key":"10.1016\/j.jcms.2017.01.008_bib32","doi-asserted-by":"crossref","first-page":"1291","DOI":"10.1016\/j.joms.2014.01.009","article-title":"Clinicopathologic features of oral squamous cell carcinoma: do they vary in different age groups?","volume":"72","author":"Troeltzsch","year":"2014","journal-title":"J\u00a0Oral Maxillofac Surg"},{"key":"10.1016\/j.jcms.2017.01.008_bib33","doi-asserted-by":"crossref","first-page":"79","DOI":"10.1016\/j.joms.2015.07.011","article-title":"Are there clinical or pathological parameters of maxillary oral squamous cell carcinoma with an influence on the occurrence of neck node metastasis? An appraisal of 92 patients","volume":"74","author":"Troeltzsch","year":"2016","journal-title":"J\u00a0Oral Maxillofac"},{"key":"10.1016\/j.jcms.2017.01.008_bib34","first-page":"829","article-title":"The diagnosis and treatment of oral cavity cancer","volume":"109","author":"Wolff","year":"2012","journal-title":"Deutsches Arzteblatt Int"},{"key":"10.1016\/j.jcms.2017.01.008_bib35","doi-asserted-by":"crossref","first-page":"583","DOI":"10.1002\/(SICI)1097-0347(199710)19:7<583::AID-HED4>3.0.CO;2-3","article-title":"Elective neck dissection versus observation in the treatment of early oral tongue carcinoma","volume":"19","author":"Yuen","year":"1997","journal-title":"Head Neck"}],"container-title":["Journal of Cranio-Maxillofacial Surgery"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1010518217300197?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1010518217300197?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,19]],"date-time":"2025-10-19T14:35:50Z","timestamp":1760884550000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1010518217300197"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2017,4]]},"references-count":35,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2017,4]]}},"alternative-id":["S1010518217300197"],"URL":"https:\/\/doi.org\/10.1016\/j.jcms.2017.01.008","relation":{},"ISSN":["1010-5182"],"issn-type":[{"value":"1010-5182","type":"print"}],"subject":[],"published":{"date-parts":[[2017,4]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Elective neck dissection in unilateral carcinomas of the tongue: Unilateral versus bilateral approach","name":"articletitle","label":"Article Title"},{"value":"Journal of Cranio-Maxillofacial Surgery","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.jcms.2017.01.008","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2017 European Association for Cranio-Maxillo-Facial Surgery. Published by Elsevier Ltd. All rights reserved.","name":"copyright","label":"Copyright"}]}}