{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,30]],"date-time":"2026-09-30T08:36:41Z","timestamp":1790757401544,"version":"4.1.0"},"reference-count":30,"publisher":"Elsevier BV","issue":"9","license":[{"start":{"date-parts":[[2021,9,1]],"date-time":"2021-09-01T00:00:00Z","timestamp":1630454400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2021,9,1]],"date-time":"2021-09-01T00:00:00Z","timestamp":1630454400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2021,4,18]],"date-time":"2021-04-18T00:00:00Z","timestamp":1618704000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Journal of Cranio-Maxillofacial Surgery"],"published-print":{"date-parts":[[2021,9]]},"DOI":"10.1016\/j.jcms.2021.03.002","type":"journal-article","created":{"date-parts":[[2021,4,30]],"date-time":"2021-04-30T00:35:54Z","timestamp":1619742954000},"page":"845-854","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":49,"title":["Long-term outcomes of implant-based dental rehabilitation in head and neck cancer patients after reconstruction with the free vascularized fibula flap"],"prefix":"10.1016","volume":"49","author":[{"given":"Johannes N.","family":"Lodders","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Frank K.J.","family":"Leusink","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Angela","family":"Ridwan-Pramana","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Henri A.H.","family":"Winters","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"K. Hakki","family":"Karagozoglu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hannah","family":"Dekker","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tymour","family":"Forouzanfar","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Engelbert A.J.M.","family":"Schulten","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.jcms.2021.03.002_bib1","first-page":"11","article-title":"The long-term efficacy of currently used dental implants: a review and proposed criteria of success","volume":"1","author":"Albrektsson","year":"1986","journal-title":"Int. J. Maxillofac. Implant"},{"key":"10.1016\/j.jcms.2021.03.002_bib2","doi-asserted-by":"crossref","first-page":"1205","DOI":"10.1016\/j.jcms.2018.05.008","article-title":"Survival of dental implants placed in vascularised fibula free flaps after jaw reconstruction","volume":"46","author":"Attia","year":"2018","journal-title":"J.\u00a0Cranio-Maxillofacial Surg."},{"key":"10.1016\/j.jcms.2021.03.002_bib3","doi-asserted-by":"crossref","first-page":"786","DOI":"10.1016\/j.jcms.2018.12.017","article-title":"Functional and aesthetic treatment outcomes after immediate jaw reconstruction using a fibula flap and dental implants","volume":"47","author":"Attia","year":"2019","journal-title":"J.\u00a0Cranio-Maxillofacial Surg."},{"key":"10.1016\/j.jcms.2021.03.002_bib4","doi-asserted-by":"crossref","first-page":"629","DOI":"10.1016\/j.jcms.2019.01.037","article-title":"The use of vascularized fibula flap in mandibular reconstruction; a comprehensive systematic review and meta-analysis of the observational studies","volume":"47","author":"Awad","year":"2019","journal-title":"J.\u00a0Cranio-Maxillofacial Surg."},{"issue":"4","key":"10.1016\/j.jcms.2021.03.002_bib5","article-title":"Hyperbaric oxygen therapy for late radiation tissue injury","volume":"2016","author":"Bennett","year":"2016","journal-title":"Cochrane Database Syst. Rev."},{"key":"10.1016\/j.jcms.2021.03.002_bib6","doi-asserted-by":"crossref","first-page":"1001","DOI":"10.1016\/S1470-2045(10)70113-3","article-title":"Reconstruction of the maxilla and midface: introducing a new classification","volume":"11","author":"Brown","year":"2010","journal-title":"Lancet Oncol."},{"key":"10.1016\/j.jcms.2021.03.002_bib7","doi-asserted-by":"crossref","first-page":"e23","DOI":"10.1016\/S1470-2045(15)00310-1","article-title":"A\u00a0new classification for mandibular defects after oncological resection","volume":"17","author":"Brown","year":"2016","journal-title":"Lancet Oncol."},{"key":"10.1016\/j.jcms.2021.03.002_bib8","first-page":"E321","article-title":"Osseointegrated implant-based dental rehabilitation in head and neck reconstruction patients","volume":"38","author":"Ch\u2019ng","year":"2015","journal-title":"Head Neck"},{"key":"10.1016\/j.jcms.2021.03.002_bib9","doi-asserted-by":"crossref","first-page":"220","DOI":"10.1111\/j.1600-0501.2005.01212.x","article-title":"Clinical outcome of dental implants placed in fibula-free flaps used for the reconstruction of maxillo-mandibular defects following ablation for tumors or osteoradionecrosis","volume":"17","author":"Chiapasco","year":"2006","journal-title":"Clin. Oral Implants Res."},{"issue":"22\u201330","key":"10.1016\/j.jcms.2021.03.002_bib10","article-title":"Osteoradionecrosis of the jaws: definition, epidemiology, staging and clinical and radiological findings. A concise review","volume":"68","author":"Chronopoulos","year":"2018","journal-title":"Int. Dent. J."},{"key":"10.1016\/j.jcms.2021.03.002_bib11","doi-asserted-by":"crossref","first-page":"140","DOI":"10.1111\/joor.12734","article-title":"The association between a mixing ability test and patient reported chewing ability in patients treated for oral malignancies","volume":"46","author":"de Groot","year":"2019","journal-title":"J.\u00a0Oral Rehabil."},{"key":"10.1016\/j.jcms.2021.03.002_bib12","series-title":"Cochrane Database Syst Rev","article-title":"Interventions for replacing missing teeth: hyperbaric oxygen therapy for irradiated patients who require dental implants","author":"Esposito","year":"2008"},{"key":"10.1016\/j.jcms.2021.03.002_bib13","doi-asserted-by":"crossref","first-page":"169","DOI":"10.11607\/jomi.3606","article-title":"Long-term results of mandibular reconstruction of continuity defects with fibula free flap and implant-borne dental rehabilitation","volume":"30","author":"Fang","year":"2015","journal-title":"Int. J. Oral Maxillofac. Implants"},{"key":"10.1016\/j.jcms.2021.03.002_bib14","article-title":"Efficacy of conventional and implant-supported mandibular resection prostheses: study overview and treatment outcomes","volume":"96","author":"Garrett","year":"2006","journal-title":"J.\u00a0Prosthet. Dent"},{"key":"10.1016\/j.jcms.2021.03.002_bib15","doi-asserted-by":"crossref","first-page":"525","DOI":"10.1007\/s00784-014-1247-9","article-title":"Masticatory rehabilitation following upper and lower jaw reconstruction using vascularised free fibula flap and enossal implants \u2014 19 years of experience with a comprehensive concept","volume":"19","author":"Hakim","year":"2015","journal-title":"Clin. Oral Invest."},{"key":"10.1016\/j.jcms.2021.03.002_bib16","doi-asserted-by":"crossref","first-page":"69","DOI":"10.1111\/j.1600-0501.2004.01076.x","article-title":"Oral rehabilitation after mandibular reconstruction using an osteocutaneous fibula free flap with endosseous implants: factors affecting the functional outcome in patients with oral cancer","volume":"16","author":"Iizuka","year":"2005","journal-title":"Clin. Oral Implants Res."},{"key":"10.1016\/j.jcms.2021.03.002_bib17","doi-asserted-by":"crossref","first-page":"419","DOI":"10.1111\/cid.12004","article-title":"Is mandibular reconstruction using vascularized fibula flaps and dental implants a reasonable treatment?","volume":"16","author":"Jacobsen","year":"2014","journal-title":"Clin. Implant Dent. Relat. Res."},{"key":"10.1016\/j.jcms.2021.03.002_bib18","doi-asserted-by":"crossref","first-page":"800","DOI":"10.1016\/j.jcms.2016.04.013","article-title":"(a) Implant supported dental rehabilitation following segmental mandibular reconstruction \u2014 quality of life outcomes of a prospective randomized trial","volume":"44","author":"Kumar","year":"2016","journal-title":"J.\u00a0Cranio-Maxillofacial Surg."},{"key":"10.1016\/j.jcms.2021.03.002_bib19","doi-asserted-by":"crossref","first-page":"855","DOI":"10.1111\/clr.13304","article-title":"Masticatory efficiency of implant-supported removable partial dental prostheses in patients with free fibula flap reconstructed mandibles: a split-mouth, observational study","volume":"29","author":"Kumar","year":"2018","journal-title":"Clin. Oral Implants Res."},{"key":"10.1016\/j.jcms.2021.03.002_bib20","doi-asserted-by":"crossref","first-page":"1849","DOI":"10.1016\/j.jcms.2016.08.023","article-title":"(b) Implants in free fibula flap supporting dental rehabilitation \u2014 implant and peri-implant related outcomes of a randomized clinical trial","volume":"44","author":"Kumar","year":"2016","journal-title":"J.\u00a0Cranio-Maxillofacial Surg."},{"key":"10.1016\/j.jcms.2021.03.002_bib21","doi-asserted-by":"crossref","first-page":"49","DOI":"10.14219\/jada.archive.1985.0074","article-title":"Prevention of osteoradionecrosis: a randomized prospective clinical trial of hyperbaric oxygen versus penicillin","volume":"111","author":"Marx","year":"1985","journal-title":"J.\u00a0Am. Dent. Assoc."},{"key":"10.1016\/j.jcms.2021.03.002_bib22","doi-asserted-by":"crossref","first-page":"852","DOI":"10.1111\/cid.12658","article-title":"Long-term results of osseointegrated implant-based dental rehabilitation in oncology patients reconstructed with a fibula free flap","volume":"20","author":"Pellegrino","year":"2018","journal-title":"Clin. Implant Dent. Relat. Res."},{"key":"10.1016\/j.jcms.2021.03.002_bib23","doi-asserted-by":"crossref","first-page":"524","DOI":"10.1016\/j.joms.2009.09.104","article-title":"Clinical evaluation of implants in radiated fibula flaps","volume":"68","author":"Salinas","year":"2010","journal-title":"J.\u00a0Oral Maxillofac. Surg."},{"key":"10.1016\/j.jcms.2021.03.002_bib24","doi-asserted-by":"crossref","first-page":"459","DOI":"10.1002\/hed.20176","article-title":"Oral rehabilitation after treatment for head and neck malignancy","volume":"27","author":"Shaw","year":"2005","journal-title":"Head Neck"},{"key":"10.1016\/j.jcms.2021.03.002_bib25","first-page":"e194","article-title":"The effect of radiotherapy on survival of dental implants in head and neck cancer patients","volume":"8","author":"Shugaa-Addin","year":"2016","journal-title":"J.\u00a0Clin. Exp. Dent."},{"key":"10.1016\/j.jcms.2021.03.002_bib26","doi-asserted-by":"crossref","first-page":"571","DOI":"10.1016\/j.oraloncology.2007.07.005","article-title":"Fibula free flap reconstruction of the mandible in cancer patients: evaluation of a combined surgical and prosthodontic treatment concept","volume":"44","author":"Smolka","year":"2008","journal-title":"Oral Oncol."},{"key":"10.1016\/j.jcms.2021.03.002_bib27","doi-asserted-by":"crossref","first-page":"580","DOI":"10.1111\/j.1600-0722.2009.00675.x","article-title":"Mixing ability test compared with a comminution test in persons with normal and compromised masticatory performance","volume":"117","author":"Speksnijder","year":"2009","journal-title":"Eur. J. Oral Sci."},{"key":"10.1016\/j.jcms.2021.03.002_bib28","first-page":"738","article-title":"Implant prosthodontic rehabilitation of fibula free-flap reconstructed mandibles: a Memorial Sloan-Kettering Cancer Center review of prognostic factors and implant outcomes","volume":"20","author":"Teoh","year":"2005","journal-title":"Int. J. Oral Maxillofac. Implants"},{"key":"10.1016\/j.jcms.2021.03.002_bib29","doi-asserted-by":"crossref","first-page":"935","DOI":"10.1288\/00005537-199109000-00004","article-title":"Functional evaluation following microvascular oromandibular reconstruction of the oral cancer patient: a comparative study of reconstructed and nonreconstructed patients","volume":"101","author":"Urken","year":"1991","journal-title":"Laryngoscope"},{"key":"10.1016\/j.jcms.2021.03.002_bib30","doi-asserted-by":"crossref","first-page":"1639","DOI":"10.1002\/hed.25134","article-title":"Comprehensive approach to functional palatomaxillary reconstruction using regional and free tissue transfer: report of reconstructive and prosthodontic outcomes of 140 patients","volume":"40","author":"Urken","year":"2018","journal-title":"Head Neck"}],"container-title":["Journal of Cranio-Maxillofacial Surgery"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1010518221001013?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1010518221001013?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,19]],"date-time":"2025-10-19T14:44:55Z","timestamp":1760885095000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1010518221001013"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,9]]},"references-count":30,"journal-issue":{"issue":"9","published-print":{"date-parts":[[2021,9]]}},"alternative-id":["S1010518221001013"],"URL":"https:\/\/doi.org\/10.1016\/j.jcms.2021.03.002","relation":{},"ISSN":["1010-5182"],"issn-type":[{"value":"1010-5182","type":"print"}],"subject":[],"published":{"date-parts":[[2021,9]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Long-term outcomes of implant-based dental rehabilitation in head and neck cancer patients after reconstruction with the free vascularized fibula flap","name":"articletitle","label":"Article Title"},{"value":"Journal of Cranio-Maxillofacial Surgery","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.jcms.2021.03.002","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2021 The Author(s). Published by Elsevier Ltd on behalf of European Association for Cranio-Maxillo-Facial Surgery.","name":"copyright","label":"Copyright"}]}}