{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,30]],"date-time":"2026-09-30T01:11:51Z","timestamp":1790730711255,"version":"4.1.0"},"reference-count":94,"publisher":"Elsevier BV","issue":"1","license":[{"start":{"date-parts":[[2011,11,1]],"date-time":"2011-11-01T00:00:00Z","timestamp":1320105600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Journal of Controlled Release"],"published-print":{"date-parts":[[2011,11]]},"DOI":"10.1016\/j.jconrel.2011.07.001","type":"journal-article","created":{"date-parts":[[2011,7,8]],"date-time":"2011-07-08T13:47:10Z","timestamp":1310132830000},"page":"2-10","source":"Crossref","is-referenced-by-count":66,"title":["Recent advances in artificial nerve conduit design: Strategies for the delivery of luminal fillers"],"prefix":"10.1016","volume":"156","author":[{"given":"Amit","family":"Pabari","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shi Yu","family":"Yang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Afshin","family":"Mosahebi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alexander M.","family":"Seifalian","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"issue":"4","key":"10.1016\/j.jconrel.2011.07.001_bb0005","doi-asserted-by":"crossref","first-page":"511","DOI":"10.1111\/j.1469-7580.2006.00623.x","article-title":"Bioengineered nerve regeneration and muscle reinnervation","volume":"209","author":"Kingham","year":"2006","journal-title":"J. Anat."},{"issue":"2","key":"10.1016\/j.jconrel.2011.07.001_bb0010","doi-asserted-by":"crossref","first-page":"408","DOI":"10.1016\/0014-4886(85)90100-1","article-title":"Cell body responses to axonal injury: traumatic axotomy versus toxic neuropathy","volume":"89","author":"Sterman","year":"1985","journal-title":"Exp. Neurol."},{"issue":"3","key":"10.1016\/j.jconrel.2011.07.001_bb0015","doi-asserted-by":"crossref","first-page":"270","DOI":"10.3171\/jns.1969.30.3part1.0270","article-title":"The metabolic background for peripheral nerve surgery","volume":"30","author":"Ducker","year":"1969","journal-title":"J. Neurosurg."},{"issue":"3","key":"10.1016\/j.jconrel.2011.07.001_bb0020","doi-asserted-by":"crossref","first-page":"475","DOI":"10.1097\/01.scs.0000249362.41170.f3","article-title":"Peripheral nerve regeneration using a three dimensionally cultured Schwann cell conduit","volume":"18","author":"Kim","year":"2007","journal-title":"J. Craniofac. Surg."},{"issue":"4","key":"10.1016\/j.jconrel.2011.07.001_bb0025","doi-asserted-by":"crossref","first-page":"1218","DOI":"10.1084\/jem.165.4.1218","article-title":"The macrophage response to central and peripheral nerve injury: A possible role for macrophages in regeneration","volume":"165","author":"Perry","year":"1987","journal-title":"J. Exp. Med."},{"issue":"Pt 1","key":"10.1016\/j.jconrel.2011.07.001_bb0030","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1046\/j.1469-7580.1999.19410001.x","article-title":"Peripheral nerve regeneration and neurotrophic factors","volume":"194","author":"Terenghi","year":"1999","journal-title":"J. Anat."},{"issue":"3","key":"10.1016\/j.jconrel.2011.07.001_bb0035","doi-asserted-by":"crossref","first-page":"481","DOI":"10.1016\/S0749-0712(21)01100-8","article-title":"Physiology of nerve repair: a research update","volume":"7","author":"Mitchell","year":"1991","journal-title":"Hand Clin."},{"issue":"1","key":"10.1016\/j.jconrel.2011.07.001_bb0040","doi-asserted-by":"crossref","first-page":"353","DOI":"10.1083\/jcb.107.1.353","article-title":"Identification of the major proteins that promote neuronal process outgrowth on Schwann cells in vitro","volume":"107","author":"Bixby","year":"1988","journal-title":"J. Cell Biol."},{"issue":"8","key":"10.1016\/j.jconrel.2011.07.001_bb0045","doi-asserted-by":"crossref","first-page":"617","DOI":"10.1038\/nrn1956","article-title":"Glial inhibition of CNS axon regeneration","volume":"7","author":"Yiu","year":"2006","journal-title":"Nat. Rev. Neurosci."},{"issue":"6","key":"10.1016\/j.jconrel.2011.07.001_bb0050","doi-asserted-by":"crossref","first-page":"395","DOI":"10.1007\/s12264-008-0218-z","article-title":"Regulation of axonal regeneration following the central nervous system injury in adult mammalian","volume":"24","author":"Liu","year":"2008","journal-title":"Neurosci. Bull."},{"issue":"4","key":"10.1016\/j.jconrel.2011.07.001_bb0055","doi-asserted-by":"crossref","first-page":"244","DOI":"10.1002\/micr.1920140406","article-title":"Percentage of nerve injuries in which primary repair can be achieved by end-to-end approximation: review of 2,181 nerve lesions","volume":"14","author":"de Medinaceli","year":"1993","journal-title":"Microsurgery"},{"issue":"4","key":"10.1016\/j.jconrel.2011.07.001_bb0060","doi-asserted-by":"crossref","first-page":"687","DOI":"10.1097\/00005373-200110000-00011","article-title":"Median, ulnar, and combined median-ulnar nerve injuries: functional outcome and return to productivity","volume":"51","author":"Jaquet","year":"2001","journal-title":"J. Trauma"},{"key":"10.1016\/j.jconrel.2011.07.001_bb0065","doi-asserted-by":"crossref","first-page":"293","DOI":"10.1146\/annurev.bioeng.5.011303.120731","article-title":"Neural tissue engineering: strategies for repair and regeneration","volume":"5","author":"Schmidt","year":"2003","journal-title":"Annu. Rev. Biomed. Eng."},{"key":"10.1016\/j.jconrel.2011.07.001_bb0070","first-page":"303","article-title":"Will it be possible to produce peripheral nerves?","volume":"11","author":"Wiberg","year":"2003","journal-title":"Surg. Technol. Int."},{"issue":"12","key":"10.1016\/j.jconrel.2011.07.001_bb0075","doi-asserted-by":"crossref","first-page":"1941","DOI":"10.1016\/j.bjps.2009.12.010","article-title":"Modern surgical management of peripheral nerve gap","volume":"63","author":"Pabari","year":"2010","journal-title":"J. Plast. Reconstr. Aesthet. Surg."},{"issue":"2","key":"10.1016\/j.jconrel.2011.07.001_bb0080","doi-asserted-by":"crossref","first-page":"232","DOI":"10.1021\/bm015533u","article-title":"Electrospinning of collagen nanofibers","volume":"3","author":"Matthews","year":"2002","journal-title":"Biomacromolecules"},{"issue":"4","key":"10.1016\/j.jconrel.2011.07.001_bb0085","doi-asserted-by":"crossref","first-page":"919","DOI":"10.1002\/jbm.a.31522","article-title":"Enhanced nerve regeneration through a bilayered chitosan tube: the effect of introduction of glycine spacer into the CYIGSR sequence","volume":"85","author":"Wang","year":"2008","journal-title":"J. Biomed. Mater. Res. A"},{"issue":"2","key":"10.1016\/j.jconrel.2011.07.001_bb0090","first-page":"557","article-title":"Influences of mechanical properties and permeability on chitosan nano\/microfiber mesh tubes as a scaffold for nerve regeneration","volume":"84","author":"Wang","year":"2008","journal-title":"J. Biomed. Mater. Res. A"},{"issue":"3","key":"10.1016\/j.jconrel.2011.07.001_bb0095","doi-asserted-by":"crossref","first-page":"841","DOI":"10.1016\/S0142-9612(01)00190-9","article-title":"Bioactive poly(l-lactic acid) conduits seeded with Schwann cells for peripheral nerve regeneration","volume":"23","author":"Evans","year":"2002","journal-title":"Biomaterials"},{"issue":"12","key":"10.1016\/j.jconrel.2011.07.001_bb0100","doi-asserted-by":"crossref","first-page":"1055","DOI":"10.1016\/j.addr.2009.07.009","article-title":"The application of nanofibrous scaffolds in neural tissue engineering","volume":"61","author":"Cao","year":"2009","journal-title":"Adv. Drug Deliv. Rev."},{"issue":"1","key":"10.1016\/j.jconrel.2011.07.001_bb0105","doi-asserted-by":"crossref","first-page":"86","DOI":"10.1016\/j.expneurol.2009.09.009","article-title":"Current applications and future perspectives of artificial nerve conduits","volume":"223","author":"Jiang","year":"2010","journal-title":"Exp Neurol."},{"issue":"5 Pt 2","key":"10.1016\/j.jconrel.2011.07.001_bb0110","doi-asserted-by":"crossref","first-page":"4109","DOI":"10.1523\/JNEUROSCI.15-05-04109.1995","article-title":"Monkey median nerve repaired by nerve graft or collagen nerve guide tube","volume":"15","author":"Archibald","year":"1995","journal-title":"J. Neurosci."},{"issue":"4","key":"10.1016\/j.jconrel.2011.07.001_bb0115","doi-asserted-by":"crossref","first-page":"258","DOI":"10.1002\/micr.20127","article-title":"Nerve repair by means of tubulization: literature review and personal clinical experience comparing biological and synthetic conduits for sensory nerve repair","volume":"25","author":"Battiston","year":"2005","journal-title":"Microsurgery"},{"issue":"3","key":"10.1016\/j.jconrel.2011.07.001_bb0120","doi-asserted-by":"crossref","first-page":"555","DOI":"10.3171\/jns.2003.99.3.0555","article-title":"Growth factor enhancement of peripheral nerve regeneration through a novel synthetic hydrogel tube","volume":"99","author":"Midha","year":"2003","journal-title":"J. Neurosurg."},{"issue":"3","key":"10.1016\/j.jconrel.2011.07.001_bb0125","doi-asserted-by":"crossref","first-page":"294","DOI":"10.1001\/archotol.127.3.294","article-title":"Brain-derived neurotrophic factor-enriched collagen tubule as a substitute for autologous nerve grafts","volume":"127","author":"Terris","year":"2001","journal-title":"Arch. Otolaryngol. Head Neck Surg."},{"issue":"4","key":"10.1016\/j.jconrel.2011.07.001_bb0130","doi-asserted-by":"crossref","first-page":"323","DOI":"10.1055\/s-2004-824891","article-title":"Ciliary neurotrophic factor for acceleration of peripheral nerve regeneration: an experimental study","volume":"20","author":"Zhang","year":"2004","journal-title":"J. Reconstr. Microsurg."},{"issue":"4","key":"10.1016\/j.jconrel.2011.07.001_bb0135","doi-asserted-by":"crossref","first-page":"661","DOI":"10.1002\/jbm.a.30194","article-title":"Novel heparin\/alginate gel combined with basic fibroblast growth factor promotes nerve regeneration in rat sciatic nerve","volume":"71","author":"Ohta","year":"2004","journal-title":"J. Biomed. Mater. Res. A"},{"issue":"4","key":"10.1016\/j.jconrel.2011.07.001_bb0140","doi-asserted-by":"crossref","first-page":"959","DOI":"10.1016\/j.actbio.2008.11.008","article-title":"Affinity-based release of glial-derived neurotrophic factor from fibrin matrices enhances sciatic nerve regeneration","volume":"5","author":"Wood","year":"2009","journal-title":"Acta Biomater."},{"issue":"6","key":"10.1016\/j.jconrel.2011.07.001_bb0145","doi-asserted-by":"crossref","first-page":"970","DOI":"10.1002\/bit.22766","article-title":"Fibrin matrices with affinity-based delivery systems and neurotrophic factors promote functional nerve regeneration","volume":"106","author":"Wood","year":"2010","journal-title":"Biotechnol. Bioeng."},{"issue":"12","key":"10.1016\/j.jconrel.2011.07.001_bb0150","doi-asserted-by":"crossref","first-page":"2008","DOI":"10.1016\/j.jhsa.2010.08.016","article-title":"Controlled delivery of glial cell line-derived neurotrophic factor enhances motor nerve regeneration","volume":"35","author":"Moore","year":"2010","journal-title":"J. Hand. Surg. Am."},{"issue":"3","key":"10.1016\/j.jconrel.2011.07.001_bb0155","doi-asserted-by":"crossref","first-page":"129","DOI":"10.1080\/02844310510006295","article-title":"Composite PHB-GGF conduit for long nerve gap repair: a long-term evaluation","volume":"39","author":"Mohanna","year":"2005","journal-title":"Scand. J. Plast. Reconstr. Surg. Hand Surg."},{"issue":"6","key":"10.1016\/j.jconrel.2011.07.001_bb0160","doi-asserted-by":"crossref","first-page":"553","DOI":"10.1046\/j.1469-7580.2003.00243.x","article-title":"A composite poly-hydroxybutyrate-glial growth factor conduit for long nerve gap repairs","volume":"203","author":"Mohanna","year":"2003","journal-title":"J. Anat."},{"issue":"5","key":"10.1016\/j.jconrel.2011.07.001_bb0165","doi-asserted-by":"crossref","first-page":"444","DOI":"10.1016\/S0007-1226(03)00134-6","article-title":"Exogenous leukaemia inhibitory factor enhances nerve regeneration after late secondary repair using a bioartificial nerve conduit","volume":"56","author":"McKay Hart","year":"2003","journal-title":"Br. J. Plast. Surg."},{"issue":"1","key":"10.1016\/j.jconrel.2011.07.001_bb0170","doi-asserted-by":"crossref","first-page":"295","DOI":"10.1016\/S0014-4886(03)00258-9","article-title":"Controlled release of nerve growth factor enhances sciatic nerve regeneration","volume":"184","author":"Lee","year":"2003","journal-title":"Exp. Neurol."},{"issue":"2","key":"10.1016\/j.jconrel.2011.07.001_bb0175","doi-asserted-by":"crossref","first-page":"395","DOI":"10.1006\/exnr.1997.6543","article-title":"Gel matrix vehicles for growth factor application in nerve gap injuries repaired with tubes: a comparison of biomatrix, collagen, and methylcellulose","volume":"146","author":"Wells","year":"1997","journal-title":"Exp. Neurol."},{"issue":"Pt 4","key":"10.1016\/j.jconrel.2011.07.001_bb0180","doi-asserted-by":"crossref","first-page":"591","DOI":"10.1046\/j.1469-7580.2000.19740591.x","article-title":"VEGF enhances intraneural angiogenesis and improves nerve regeneration after axotomy","volume":"197","author":"Hobson","year":"2000","journal-title":"J. Anat."},{"issue":"1","key":"10.1016\/j.jconrel.2011.07.001_bb0185","first-page":"47","article-title":"Increased vascularisation enhances axonal regeneration within an acellular nerve conduit","volume":"84","author":"Hobson","year":"2002","journal-title":"Ann. R. Coll. Surg. Engl."},{"issue":"1","key":"10.1016\/j.jconrel.2011.07.001_bb0190","doi-asserted-by":"crossref","first-page":"243","DOI":"10.1006\/exnr.1997.6650","article-title":"Influence of collagen and laminin gels concentration on nerve regeneration after resection and tube repair","volume":"149","author":"Labrador","year":"1998","journal-title":"Exp. Neurol."},{"issue":"4","key":"10.1016\/j.jconrel.2011.07.001_bb0195","doi-asserted-by":"crossref","first-page":"585","DOI":"10.1007\/s10529-009-0186-z","article-title":"A novel basic fibroblast growth factor delivery system fabricated with heparin-incorporated fibrin\u2013fibronectin matrices for repairing rat sciatic nerve disruptions","volume":"32","author":"Han","year":"2010","journal-title":"Biotechnol. Lett."},{"issue":"1","key":"10.1016\/j.jconrel.2011.07.001_bb0200","doi-asserted-by":"crossref","first-page":"131","DOI":"10.1002\/jcp.1041310119","article-title":"Heparin modulation of the neurotropic effects of acidic and basic fibroblast growth factors and nerve growth factor on PC12 cells","volume":"131","author":"Neufeld","year":"1987","journal-title":"J. Cell. Physiol."},{"issue":"2","key":"10.1016\/j.jconrel.2011.07.001_bb0205","doi-asserted-by":"crossref","first-page":"337","DOI":"10.1042\/bst0310337","article-title":"Interaction between glial-cell-line-derived neurotrophic factor (GDNF) and 2-O-sulphated heparin-related glycosaminoglycans","volume":"31","author":"Rider","year":"2003","journal-title":"Biochem. Soc. Trans."},{"issue":"Pt 23","key":"10.1016\/j.jconrel.2011.07.001_bb0210","doi-asserted-by":"crossref","first-page":"4495","DOI":"10.1242\/jcs.00114","article-title":"Signalling by glial cell line-derived neurotrophic factor (GDNF) requires heparan sulphate glycosaminoglycan","volume":"115","author":"Barnett","year":"2002","journal-title":"J. Cell Sci."},{"issue":"15","key":"10.1016\/j.jconrel.2011.07.001_bb0215","doi-asserted-by":"crossref","first-page":"1913","DOI":"10.1097\/00001756-200210280-00016","article-title":"Heparin facilitates glial cell line-derived neurotrophic factor signal transduction","volume":"13","author":"Tanaka","year":"2002","journal-title":"Neuroreport"},{"issue":"1","key":"10.1016\/j.jconrel.2011.07.001_bb0220","doi-asserted-by":"crossref","first-page":"149","DOI":"10.1016\/S0168-3659(00)00296-0","article-title":"Controlled release of nerve growth factor from a heparin-containing fibrin-based cell ingrowth matrix","volume":"69","author":"Sakiyama-Elbert","year":"2000","journal-title":"J. Control. Release"},{"issue":"6","key":"10.1016\/j.jconrel.2011.07.001_bb0225","doi-asserted-by":"crossref","first-page":"771","DOI":"10.1163\/156856209X445285","article-title":"Heparin-binding-affinity-based delivery systems releasing nerve growth factor enhance sciatic nerve regeneration","volume":"21","author":"Wood","year":"2010","journal-title":"J. Biomater. Sci. Polym. Ed."},{"issue":"4","key":"10.1016\/j.jconrel.2011.07.001_bb0230","doi-asserted-by":"crossref","first-page":"589","DOI":"10.1046\/j.1460-9568.2002.01892.x","article-title":"GDNF and NGF released by synthetic guidance channels support sciatic nerve regeneration across a long gap","volume":"15","author":"Fine","year":"2002","journal-title":"Eur. J. Neurosci."},{"issue":"17","key":"10.1016\/j.jconrel.2011.07.001_bb0235","first-page":"2032","article-title":"A novel biosynthetic hybrid scaffold seeded with olfactory ensheathing cells for treatment of spinal cord injuries","volume":"122","author":"Qian","year":"2009","journal-title":"Chin. Med. J. (Engl.)"},{"issue":"9","key":"10.1016\/j.jconrel.2011.07.001_bb0240","first-page":"1104","article-title":"Effects of neurotrophic factor 3 gene modified SC on sciatic nerve regeneration in rats","volume":"23","author":"Dong","year":"2009","journal-title":"Zhongguo Xiu Fu Chong Jian Wai Ke Za Zhi"},{"issue":"1","key":"10.1016\/j.jconrel.2011.07.001_bb0245","doi-asserted-by":"crossref","first-page":"33","DOI":"10.1016\/j.biomaterials.2007.08.045","article-title":"Differences between the effect of anisotropic and isotropic laminin and nerve growth factor presenting scaffolds on nerve regeneration across long peripheral nerve gaps","volume":"29","author":"Dodla","year":"2008","journal-title":"Biomaterials"},{"issue":"2","key":"10.1016\/j.jconrel.2011.07.001_bb0250","doi-asserted-by":"crossref","first-page":"209","DOI":"10.1089\/107632703764664684","article-title":"Addition of fibronectin to alginate matrix improves peripheral nerve regeneration in tissue-engineered conduits","volume":"9","author":"Mosahebi","year":"2003","journal-title":"Tissue Eng."},{"issue":"2","key":"10.1016\/j.jconrel.2011.07.001_bb0255","doi-asserted-by":"crossref","first-page":"163","DOI":"10.1177\/0885328204045580","article-title":"In vitro and in vivo effects of Ginkgo biloba extract EGb 761 on seeded Schwann cells within poly(dl-lactic acid-co-glycolic acid) conduits for peripheral nerve regeneration","volume":"19","author":"Hsu","year":"2004","journal-title":"J. Biomater. Appl."},{"issue":"2","key":"10.1016\/j.jconrel.2011.07.001_bb0260","doi-asserted-by":"crossref","first-page":"120","DOI":"10.1002\/glia.20025","article-title":"FK506 enhances regeneration of axons across long peripheral nerve gaps repaired with collagen guides seeded with allogeneic Schwann cells","volume":"47","author":"Udina","year":"2004","journal-title":"Glia"},{"issue":"1","key":"10.1016\/j.jconrel.2011.07.001_bb0265","doi-asserted-by":"crossref","first-page":"118","DOI":"10.1016\/j.biomaterials.2007.08.023","article-title":"The use of keratin biomaterials derived from human hair for the promotion of rapid regeneration of peripheral nerves","volume":"29","author":"Sierpinski","year":"2008","journal-title":"Biomaterials"},{"issue":"9","key":"10.1016\/j.jconrel.2011.07.001_bb0270","doi-asserted-by":"crossref","first-page":"1541","DOI":"10.1016\/j.jhsa.2008.05.034","article-title":"Peripheral nerve regeneration using a keratin-based scaffold: long-term functional and histological outcomes in a mouse model","volume":"33","author":"Apel","year":"2008","journal-title":"J. Hand. Surg. Am."},{"issue":"5","key":"10.1016\/j.jconrel.2011.07.001_bb0275","doi-asserted-by":"crossref","first-page":"1703","DOI":"10.1089\/ten.tea.2009.0381","article-title":"Cell-laden hydrogel constructs of hyaluronic acid, collagen, and laminin for neural tissue engineering","volume":"16","author":"Suri","year":"2010","journal-title":"Tissue Eng. Part A."},{"issue":"5","key":"10.1016\/j.jconrel.2011.07.001_bb0280","doi-asserted-by":"crossref","first-page":"525","DOI":"10.1089\/107632701753213156","article-title":"A novel use of alginate hydrogel as Schwann cell matrix","volume":"7","author":"Mosahebi","year":"2001","journal-title":"Tissue Eng."},{"issue":"1","key":"10.1016\/j.jconrel.2011.07.001_bb0285","doi-asserted-by":"crossref","first-page":"156","DOI":"10.1002\/jbm.b.30128","article-title":"Electrospinning of gelatin fibers and gelatin\/PCL composite fibrous scaffolds","volume":"72","author":"Zhang","year":"2005","journal-title":"J. Biomed. Mater. Res. B Appl. Biomater."},{"issue":"9\u201310","key":"10.1016\/j.jconrel.2011.07.001_bb0290","doi-asserted-by":"crossref","first-page":"1611","DOI":"10.1089\/ten.2005.11.1611","article-title":"Neural tissue engineering: a self-organizing collagen guidance conduit","volume":"11","author":"Phillips","year":"2005","journal-title":"Tissue Eng."},{"issue":"1","key":"10.1016\/j.jconrel.2011.07.001_bb0295","doi-asserted-by":"crossref","first-page":"32","DOI":"10.1016\/j.ijom.2006.06.005","article-title":"Improvement of peripheral nerve regeneration by a tissue-engineered nerve filled with ectomesenchymal stem cells","volume":"36","author":"Nie","year":"2007","journal-title":"Int. J. Oral Maxillofac. Surg."},{"issue":"5","key":"10.1016\/j.jconrel.2011.07.001_bb0300","doi-asserted-by":"crossref","first-page":"806","DOI":"10.3171\/jns.2004.101.5.0806","article-title":"Peripheral nerve regeneration by transplantation of bone marrow stromal cell-derived Schwann cells in adult rats","volume":"101","author":"Mimura","year":"2004","journal-title":"J. Neurosurg."},{"issue":"2","key":"10.1016\/j.jconrel.2011.07.001_bb0305","doi-asserted-by":"crossref","first-page":"214","DOI":"10.1002\/ar.20844","article-title":"Assessment of axonal growth into collagen nerve guides containing VEGF-transfected stem cells in matrigel","volume":"292","author":"Kempton","year":"2009","journal-title":"Anat. Rec. (Hoboken)"},{"issue":"3","key":"10.1016\/j.jconrel.2011.07.001_bb0310","doi-asserted-by":"crossref","first-page":"547","DOI":"10.1089\/ten.tea.2007.0342","article-title":"The effect of pulse-released nerve growth factor from genipin-crosslinked gelatin in Schwann cell-seeded polycaprolactone conduits on large-gap peripheral nerve regeneration","volume":"15","author":"Chang","year":"2009","journal-title":"Tissue Eng. Part A"},{"issue":"2","key":"10.1016\/j.jconrel.2011.07.001_bb0315","doi-asserted-by":"crossref","first-page":"586","DOI":"10.1002\/jbm.a.32252","article-title":"Effects of nerve growth factor from genipin-crosslinked gelatin in polycaprolactone conduit on peripheral nerve regeneration\u2014in vitro and in vivo","volume":"91","author":"Chang","year":"2009","journal-title":"J. Biomed. Mater. Res. A"},{"issue":"2","key":"10.1016\/j.jconrel.2011.07.001_bb0320","doi-asserted-by":"crossref","first-page":"563","DOI":"10.1016\/j.ejpb.2008.01.014","article-title":"Controlled nerve growth factor release from multi-ply alginate\/chitosan-based nerve conduits","volume":"69","author":"Pfister","year":"2008","journal-title":"Eur. J. Pharm. Biopharm."},{"issue":"9","key":"10.1016\/j.jconrel.2011.07.001_bb0325","doi-asserted-by":"crossref","first-page":"2018","DOI":"10.1016\/j.biomaterials.2005.09.042","article-title":"Nerve guidance channels as drug delivery vehicles","volume":"27","author":"Piotrowicz","year":"2006","journal-title":"Biomaterials"},{"issue":"1","key":"10.1016\/j.jconrel.2011.07.001_bb0330","doi-asserted-by":"crossref","first-page":"135","DOI":"10.1002\/jbm.a.31047","article-title":"Nerve growth factor-immobilized polypyrrole: bioactive electrically conducting polymer for enhanced neurite extension","volume":"81","author":"Gomez","year":"2007","journal-title":"J. Biomed. Mater. Res. A"},{"issue":"3","key":"10.1016\/j.jconrel.2011.07.001_bb0335","doi-asserted-by":"crossref","first-page":"522","DOI":"10.1002\/jbm.a.10008","article-title":"Acceleration effect of basic fibroblast growth factor on the regeneration of peripheral nerve through a 15-mm gap","volume":"66","author":"Wang","year":"2003","journal-title":"J. Biomed. Mater. Res. A"},{"issue":"5","key":"10.1016\/j.jconrel.2011.07.001_bb0340","doi-asserted-by":"crossref","first-page":"1109","DOI":"10.1111\/j.1460-9568.2007.05748.x","article-title":"Variations in glial cell line-derived neurotrophic factor release from biodegradable nerve conduits modify the rate of functional motor recovery after rat primary nerve repairs","volume":"26","author":"Piquilloud","year":"2007","journal-title":"Eur. J. Neurosci."},{"issue":"2","key":"10.1016\/j.jconrel.2011.07.001_bb0345","doi-asserted-by":"crossref","first-page":"168","DOI":"10.1016\/j.jconrel.2009.12.017","article-title":"Collagen nerve conduits releasing the neurotrophic factors GDNF and NGF","volume":"143","author":"Madduri","year":"2010","journal-title":"J. Control Release."},{"issue":"5","key":"10.1016\/j.jconrel.2011.07.001_bb0350","doi-asserted-by":"crossref","first-page":"587","DOI":"10.1177\/1753193408090755","article-title":"Schwann cell strip for peripheral nerve repair","volume":"33","author":"Kalbermatten","year":"2008","journal-title":"J. Hand Surg. Eur. Vol."},{"issue":"3","key":"10.1016\/j.jconrel.2011.07.001_bb0355","doi-asserted-by":"crossref","first-page":"96","DOI":"10.1002\/micr.1016","article-title":"A new artificial nerve graft containing rolled Schwann cell monolayers","volume":"21","author":"Hadlock","year":"2001","journal-title":"Microsurgery"},{"issue":"2","key":"10.1016\/j.jconrel.2011.07.001_bb0360","doi-asserted-by":"crossref","first-page":"119","DOI":"10.1089\/107632700320748","article-title":"A polymer foam conduit seeded with Schwann cells promotes guided peripheral nerve regeneration","volume":"6","author":"Hadlock","year":"2000","journal-title":"Tissue Eng."},{"issue":"16","key":"10.1016\/j.jconrel.2011.07.001_bb0365","doi-asserted-by":"crossref","first-page":"2603","DOI":"10.1016\/j.biomaterials.2007.01.042","article-title":"Patterned PLG substrates for localized DNA delivery and directed neurite extension","volume":"28","author":"Houchin-Ray","year":"2007","journal-title":"Biomaterials"},{"issue":"3","key":"10.1016\/j.jconrel.2011.07.001_bb0370","doi-asserted-by":"crossref","first-page":"151","DOI":"10.1088\/1741-2560\/1\/3\/004","article-title":"Synergistic effects of micropatterned biodegradable conduits and Schwann cells on sciatic nerve regeneration","volume":"1","author":"Rutkowski","year":"2004","journal-title":"J. Neural Eng."},{"issue":"3","key":"10.1016\/j.jconrel.2011.07.001_bb0375","doi-asserted-by":"crossref","first-page":"35003","DOI":"10.1088\/1748-6041\/5\/3\/035003","article-title":"Evaluation of the chitosan\/glycerol-beta-phosphate disodium salt hydrogel application in peripheral nerve regeneration","volume":"5","author":"Zheng","year":"2010","journal-title":"Biomed. Mater."},{"issue":"9","key":"10.1016\/j.jconrel.2011.07.001_bb0380","doi-asserted-by":"crossref","first-page":"1544","DOI":"10.1016\/j.bjps.2009.09.012","article-title":"Adipose-derived stem cells enhance peripheral nerve regeneration","volume":"63","author":"di Summa","year":"2010","journal-title":"J. Plast. Reconstr. Aesthet. Surg."},{"issue":"17","key":"10.1016\/j.jconrel.2011.07.001_bb0385","doi-asserted-by":"crossref","first-page":"3765","DOI":"10.1016\/S0142-9612(02)00116-3","article-title":"Polyphosphoester microspheres for sustained release of biologically active nerve growth factor","volume":"23","author":"Xu","year":"2002","journal-title":"Biomaterials"},{"issue":"11","key":"10.1016\/j.jconrel.2011.07.001_bb0390","doi-asserted-by":"crossref","first-page":"1383","DOI":"10.1114\/1.1626118","article-title":"Rational design of contact guiding, neurotrophic matrices for peripheral nerve regeneration","volume":"31","author":"Rosner","year":"2003","journal-title":"Ann. Biomed. Eng."},{"issue":"13","key":"10.1016\/j.jconrel.2011.07.001_bb0395","doi-asserted-by":"crossref","first-page":"2405","DOI":"10.1016\/S0142-9612(03)00109-1","article-title":"Peripheral nerve regeneration with sustained release of poly(phosphoester) microencapsulated nerve growth factor within nerve guide conduits","volume":"24","author":"Xu","year":"2003","journal-title":"Biomaterials"},{"issue":"4","key":"10.1016\/j.jconrel.2011.07.001_bb0400","doi-asserted-by":"crossref","first-page":"293","DOI":"10.1002\/micr.20869","article-title":"Rat sciatic nerve repair with a poly-lactic-co-glycolic acid scaffold and nerve growth factor releasing microspheres","volume":"31","author":"de","year":"2011","journal-title":"Microsurgery"},{"issue":"2","key":"10.1016\/j.jconrel.2011.07.001_bb0405","doi-asserted-by":"crossref","first-page":"400","DOI":"10.1016\/j.jconrel.2005.10.019","article-title":"Incorporation of protein-eluting microspheres into biodegradable nerve guidance channels for controlled release","volume":"110","author":"Goraltchouk","year":"2006","journal-title":"J. Control. Release"},{"issue":"3","key":"10.1016\/j.jconrel.2011.07.001_bb0410","doi-asserted-by":"crossref","first-page":"433","DOI":"10.1016\/j.jconrel.2005.02.022","article-title":"Neurotrophin releasing single and multiple lumen nerve conduits","volume":"104","author":"Yang","year":"2005","journal-title":"J. Control. Release"},{"issue":"11","key":"10.1016\/j.jconrel.2011.07.001_bb0415","doi-asserted-by":"crossref","first-page":"1266","DOI":"10.1080\/00016480801935517","article-title":"Experimental study on repair of the facial nerve with Schwann cells transfected with GDNF genes and PLGA conduits","volume":"128","author":"Zhou","year":"2008","journal-title":"Acta Otolaryngol."},{"key":"10.1016\/j.jconrel.2011.07.001_bb0420","first-page":"1","article-title":"Transplantation of neural stem cells overexpressing glia-derived neurotrophic factor promotes facial nerve regeneration","author":"Shi","year":"2008","journal-title":"Acta Otolaryngol."},{"issue":"2","key":"10.1016\/j.jconrel.2011.07.001_bb0425","doi-asserted-by":"crossref","first-page":"202","DOI":"10.1016\/j.jneumeth.2009.11.023","article-title":"Genetically modified canine Schwann cells\u2013In vitro and in vivo evaluation of their suitability for peripheral nerve tissue engineering","volume":"186","author":"Schmitte","year":"2010","journal-title":"J Neurosci Methods."},{"issue":"7","key":"10.1016\/j.jconrel.2011.07.001_bb0430","doi-asserted-by":"crossref","first-page":"6141","DOI":"10.1128\/JVI.73.7.6141-6146.1999","article-title":"Frequency and stability of chromosomal integration of adenovirus vectors","volume":"73","author":"Harui","year":"1999","journal-title":"J. Virol."},{"issue":"2","key":"10.1016\/j.jconrel.2011.07.001_bb0435","doi-asserted-by":"crossref","first-page":"135","DOI":"10.2174\/1566523024605591","article-title":"Adenovirus as an integrating vector","volume":"2","author":"Mitani","year":"2002","journal-title":"Curr. Gene Ther."},{"issue":"1","key":"10.1016\/j.jconrel.2011.07.001_bb0440","doi-asserted-by":"crossref","first-page":"179","DOI":"10.1016\/j.expneurol.2006.05.027","article-title":"GDNF gene delivery via the p75(NTR) receptor rescues injured motor neurons","volume":"202","author":"Barati","year":"2006","journal-title":"Exp. Neurol."},{"issue":"11","key":"10.1016\/j.jconrel.2011.07.001_bb0445","doi-asserted-by":"crossref","first-page":"2477","DOI":"10.1016\/j.biomaterials.2005.11.016","article-title":"Nerve growth factor expression by PLG-mediated lipofection","volume":"27","author":"Whittlesey","year":"2006","journal-title":"Biomaterials"},{"issue":"4","key":"10.1016\/j.jconrel.2011.07.001_bb0450","doi-asserted-by":"crossref","first-page":"343","DOI":"10.1007\/BF02584524","article-title":"Principles of the design and operation of generic osmotic pumps for the delivery of semisolid or liquid drug formulations","volume":"4","author":"Theeuwes","year":"1976","journal-title":"Ann. Biomed. Eng."},{"issue":"15","key":"10.1016\/j.jconrel.2011.07.001_bb0455","doi-asserted-by":"crossref","first-page":"4447","DOI":"10.1016\/j.biomaterials.2010.02.018","article-title":"The use of injectable forms of fibrin and fibronectin to support axonal ingrowth after spinal cord injury","volume":"31","author":"King","year":"2010","journal-title":"Biomaterials."},{"issue":"1","key":"10.1016\/j.jconrel.2011.07.001_bb0460","doi-asserted-by":"crossref","first-page":"119","DOI":"10.1016\/S0165-0270(98)00130-7","article-title":"Evaluation of peripheral nerve regeneration by nerve growth factor locally administered with a novel system","volume":"85","author":"Santos","year":"1998","journal-title":"J. Neurosci. Methods"},{"issue":"4","key":"10.1016\/j.jconrel.2011.07.001_bb0465","doi-asserted-by":"crossref","first-page":"367","DOI":"10.1177\/1545968307313507","article-title":"Effects of electrical stimulation at different frequencies on regeneration of transected peripheral nerve","volume":"22","author":"Lu","year":"2008","journal-title":"Neurorehabil. Neural Repair"},{"issue":"2","key":"10.1016\/j.jconrel.2011.07.001_bb0470","doi-asserted-by":"crossref","first-page":"610","DOI":"10.1016\/S0014-4886(03)00183-3","article-title":"Glial cell line-derived neurotrophic factor and brain-derived neurotrophic factor sustain the axonal regeneration of chronically axotomized motoneurons in vivo","volume":"183","author":"Boyd","year":"2003","journal-title":"Exp. Neurol."}],"container-title":["Journal of Controlled Release"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0168365911004780?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0168365911004780?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2021,11,27]],"date-time":"2021-11-27T19:39:07Z","timestamp":1638041947000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0168365911004780"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2011,11]]},"references-count":94,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2011,11]]}},"alternative-id":["S0168365911004780"],"URL":"https:\/\/doi.org\/10.1016\/j.jconrel.2011.07.001","relation":{},"ISSN":["0168-3659"],"issn-type":[{"value":"0168-3659","type":"print"}],"subject":[],"published":{"date-parts":[[2011,11]]}}}