{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,22]],"date-time":"2026-09-22T21:34:35Z","timestamp":1790112875250,"version":"4.0.1"},"reference-count":21,"publisher":"Elsevier BV","issue":"2","license":[{"start":{"date-parts":[[2012,6,1]],"date-time":"2012-06-01T00:00:00Z","timestamp":1338508800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Journal of Controlled Release"],"published-print":{"date-parts":[[2012,6]]},"DOI":"10.1016\/j.jconrel.2012.01.040","type":"journal-article","created":{"date-parts":[[2012,2,3]],"date-time":"2012-02-03T00:19:18Z","timestamp":1328228358000},"page":"330-338","source":"Crossref","is-referenced-by-count":13,"title":["Antiviral effect of HPMPC (Cidofovir\u00ae), entrapped in cationic liposomes: In vitro study on MDBK cell and BHV-1 virus"],"prefix":"10.1016","volume":"160","author":[{"given":"Zina","family":"Korvasov\u00e1","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Luk\u00e1\u0161","family":"Dra\u0161ar","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Josef","family":"Ma\u0161ek","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pavl\u00edna Tur\u00e1nek","family":"Knotigov\u00e1","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pavel","family":"Kulich","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"J\u00e1n","family":"Matia\u0161ovic","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kamil","family":"Kova\u0159\u010d\u00edk","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Eli\u0161ka","family":"Bartheldyov\u00e1","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"\u0160t\u011bp\u00e1n","family":"Koudelka","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michaela","family":"\u0160krabalov\u00e1","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Andrew D.","family":"Miller","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anton\u00edn","family":"Hol\u00fd","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Miroslav","family":"Ledvina","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jaroslav","family":"Tur\u00e1nek","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.jconrel.2012.01.040_bb0005","doi-asserted-by":"crossref","first-page":"85","DOI":"10.1002\/rmv.1980030205","article-title":"Therapeutic potential of HPMPC as an antiviral drug","volume":"3","author":"De Clercq","year":"1993","journal-title":"Rev. Med. Virol."},{"key":"10.1016\/j.jconrel.2012.01.040_bb0010","doi-asserted-by":"crossref","first-page":"11391","DOI":"10.1016\/j.tet.2007.08.081","article-title":"Synthesis of phosphonomethoxyethyl or 1,3-bis(phosphonomethoxy)propan-2-yl lipophilic esters of acyclic nucleoside phosphonates","volume":"63","author":"Vrbkova","year":"2007","journal-title":"Tetrahedron"},{"key":"10.1016\/j.jconrel.2012.01.040_bb0015","first-page":"351","article-title":"Delivery of Antiviral Agents in Liposomes","volume":"Vol. 391","author":"Duzgunes","year":"2005"},{"key":"10.1016\/j.jconrel.2012.01.040_bb0020","doi-asserted-by":"crossref","first-page":"261","DOI":"10.1007\/BF03402063","article-title":"BHV-1: New molecular approaches to control a common and widespread infection","volume":"5","author":"Turin","year":"1999","journal-title":"Mol. Med."},{"key":"10.1016\/j.jconrel.2012.01.040_bb0025","doi-asserted-by":"crossref","first-page":"2470","DOI":"10.1135\/cccc19892470","article-title":"Acyclic nucleotide analogs \u2013 Synthesis of (3-hydroxy-2-phosphonylmethoxypropyl) derivatives of heterocyclic bases","volume":"54","author":"Holy","year":"1989","journal-title":"Collect Czechoslov Chem Commun."},{"key":"10.1016\/j.jconrel.2012.01.040_bb0110","doi-asserted-by":"crossref","first-page":"15.4.1","DOI":"10.1002\/0471142700.nc1504s43","article-title":"Synthesis of Peptidomimetic Conjugates of Cyclic Nucleoside Phosphonates","volume":"43","author":"Serpi","year":"2010","journal-title":"Curr. Protoc. Nucleic Acid Chem."},{"key":"10.1016\/j.jconrel.2012.01.040_bb0035","series-title":"Virology: a Laboratory Manual","author":"Burleson","year":"1992"},{"key":"10.1016\/j.jconrel.2012.01.040_bb0040","doi-asserted-by":"crossref","first-page":"970","DOI":"10.1039\/b307062j","article-title":"Synthetic, self-assembly ABCD nanoparticles; a structural paradigm for viable synthetic non-viral vectors","volume":"34","author":"Kostarelos","year":"2005","journal-title":"Chem. Soc. Rev."},{"key":"10.1016\/j.jconrel.2012.01.040_bb0045","doi-asserted-by":"crossref","first-page":"234","DOI":"10.1177\/030089160809400216","article-title":"Towards safe nanoparticle technologies for nucleic acid therapeutics","volume":"94","author":"Miller","year":"2008","journal-title":"Tumori"},{"key":"10.1016\/j.jconrel.2012.01.040_bb0050","doi-asserted-by":"crossref","first-page":"1023","DOI":"10.1016\/S0026-895X(25)09229-6","article-title":"Cationic lipids enhance cellular uptake and activity of phosphorothioate antisense oligonucleotides","volume":"41","author":"Bennett","year":"1992","journal-title":"Mol. Pharmacol."},{"key":"10.1016\/j.jconrel.2012.01.040_bb0055","doi-asserted-by":"crossref","first-page":"163","DOI":"10.1016\/S0168-3659(97)01632-5","article-title":"Inhibition of cytomegalovirus late antigen expression and cytomegalovirus replication in human fibroblasts and differentiated monocytic cells by liposome-encapsulated foscarnet","volume":"47","author":"Bergersa","year":"1997","journal-title":"J. Control. Release"},{"key":"10.1016\/j.jconrel.2012.01.040_bb0060","doi-asserted-by":"crossref","first-page":"100","DOI":"10.1016\/j.jconrel.2006.04.014","article-title":"Toxicity of cationic lipids and cationic polymers in gene delivery","volume":"114","author":"Lv","year":"2006","journal-title":"J. Control. Release"},{"key":"10.1016\/j.jconrel.2012.01.040_bb0065","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.jconrel.2003.09.013","article-title":"An overview of current delivery systems in cancer gene therapy","volume":"94","author":"El-Aneed","year":"2004","journal-title":"J. Control. Release"},{"key":"10.1016\/j.jconrel.2012.01.040_bb0070","doi-asserted-by":"crossref","first-page":"9025","DOI":"10.1021\/bi00152a045","article-title":"Inhibition of protein kinase C by cationic amphiphiles","volume":"31","author":"Bottega","year":"1992","journal-title":"Biochemistry"},{"key":"10.1016\/j.jconrel.2012.01.040_bb0075","doi-asserted-by":"crossref","first-page":"1071","DOI":"10.1128\/JVI.79.2.1071-1083.2005","article-title":"Impairment of Nuclear Pores in Bovine Herpesvirus 1-Infected MDBK Cells","volume":"79","author":"Wild","year":"2005","journal-title":"J. Virol."},{"key":"10.1016\/j.jconrel.2012.01.040_bb0080","doi-asserted-by":"crossref","first-page":"135","DOI":"10.1006\/smvy.1993.1009","article-title":"Structure and assembly of herpesviruses","volume":"4","author":"Rixon","year":"1993","journal-title":"Semin Virol."},{"key":"10.1016\/j.jconrel.2012.01.040_bb0115","doi-asserted-by":"crossref","first-page":"3191","DOI":"10.1128\/JVI.77.5.3191-3203.2003","article-title":"Envelopment of human cytomegalovirus occurs by budding into Golgiderived vacuole compartments positive for gB, Rab 3, trans-Golgi network 46, and mannosidase II","volume":"77","author":"Homman-Loudiyi","year":"2003","journal-title":"J. Virol."},{"key":"10.1016\/j.jconrel.2012.01.040_bb0090","doi-asserted-by":"crossref","first-page":"1103","DOI":"10.1007\/s10350-004-7287-5","article-title":"Topical Cidofovir (HPMPC) Is an Effective Adjuvant to Surgical Treatment of Anogenital Condylomata Acuminata","volume":"46","author":"Coremans","year":"2003","journal-title":"Dis. Colon Rectum"},{"key":"10.1016\/j.jconrel.2012.01.040_bb0095","doi-asserted-by":"crossref","first-page":"18","DOI":"10.1093\/infdis\/173.1.18","article-title":"Liposome-encapsulated (S)-1-(3-hydroxy-2-phosphonylmethoxypropyl) cytosine for long-acting therapy of viral retinitis","volume":"173","author":"Kuppermann","year":"1996","journal-title":"J. Infect. Dis."},{"key":"10.1016\/j.jconrel.2012.01.040_bb0100","doi-asserted-by":"crossref","first-page":"254","DOI":"10.1016\/j.ejps.2010.06.012","article-title":"Cidofovir-loaded liposomes: an intro-study using BCBL-1 cell line as a model for primary effusion lymphoma","volume":"41","author":"Ruozi","year":"2010","journal-title":"Eur. J. Pharm. Sci."},{"key":"10.1016\/j.jconrel.2012.01.040_bb0105","doi-asserted-by":"crossref","first-page":"706","DOI":"10.1021\/mp800157x","article-title":"Controlling HBV replication in vivo by intravenous administration of triggered PEGylated siRNA-nanoparticles","volume":"6","author":"Carmona","year":"2009","journal-title":"Mol. Pharm."}],"container-title":["Journal of Controlled Release"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0168365912000703?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0168365912000703?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,3,19]],"date-time":"2025-03-19T19:43:11Z","timestamp":1742413391000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0168365912000703"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2012,6]]},"references-count":21,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2012,6]]}},"alternative-id":["S0168365912000703"],"URL":"https:\/\/doi.org\/10.1016\/j.jconrel.2012.01.040","relation":{},"ISSN":["0168-3659"],"issn-type":[{"value":"0168-3659","type":"print"}],"subject":[],"published":{"date-parts":[[2012,6]]}}}