{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,5]],"date-time":"2026-10-05T05:32:02Z","timestamp":1791178322119,"version":"4.1.0"},"reference-count":55,"publisher":"Elsevier BV","issue":"3","license":[{"start":{"date-parts":[[2012,8,1]],"date-time":"2012-08-01T00:00:00Z","timestamp":1343779200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2012,8,1]],"date-time":"2012-08-01T00:00:00Z","timestamp":1343779200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2012,8,1]],"date-time":"2012-08-01T00:00:00Z","timestamp":1343779200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2012,8,1]],"date-time":"2012-08-01T00:00:00Z","timestamp":1343779200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2012,8,1]],"date-time":"2012-08-01T00:00:00Z","timestamp":1343779200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2012,8,1]],"date-time":"2012-08-01T00:00:00Z","timestamp":1343779200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2012,8,1]],"date-time":"2012-08-01T00:00:00Z","timestamp":1343779200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Journal of Controlled Release"],"published-print":{"date-parts":[[2012,8]]},"DOI":"10.1016\/j.jconrel.2012.05.011","type":"journal-article","created":{"date-parts":[[2012,5,14]],"date-time":"2012-05-14T19:12:23Z","timestamp":1337022743000},"page":"735-745","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":105,"title":["Enhanced skin permeation using polyarginine modified nanostructured lipid carriers"],"prefix":"10.1016","volume":"161","author":[{"given":"Punit","family":"P. Shah","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pinaki","family":"R. Desai","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Debra","family":"Channer","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mandip","family":"Singh","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.jconrel.2012.05.011_bb0005","doi-asserted-by":"crossref","first-page":"68","DOI":"10.1016\/j.ejpb.2011.05.012","article-title":"In vitro penetration properties of solid lipid nanoparticles in intact and barrier-impaired skin","volume":"79","author":"Jensen","year":"2011","journal-title":"Eur. J. Pharm. Biopharm."},{"key":"10.1016\/j.jconrel.2012.05.011_bb0010","doi-asserted-by":"crossref","first-page":"470","DOI":"10.1007\/BF01837912","article-title":"Involvement of substance P as a mediator in capsaicin-induced mouse ear oedema","volume":"44","author":"Inoue","year":"1995","journal-title":"Inflamm. Res."},{"key":"10.1016\/j.jconrel.2012.05.011_bb0015","doi-asserted-by":"crossref","first-page":"108","DOI":"10.1023\/B:PHAM.0000012157.80716.73","article-title":"Percutaneous absorption and anti-inflammatory effect of a substance P receptor antagonist: spantide II","volume":"21","author":"Babu","year":"2004","journal-title":"Pharm. Res."},{"key":"10.1016\/j.jconrel.2012.05.011_bb0020","doi-asserted-by":"crossref","first-page":"E565","DOI":"10.1208\/pt060471","article-title":"In vitro and in vivo evaluation of topical formulations of spantide II","volume":"6","author":"Kikwai","year":"2005","journal-title":"AAPS PharmSciTech"},{"key":"10.1016\/j.jconrel.2012.05.011_bb0025","doi-asserted-by":"crossref","first-page":"415","DOI":"10.1016\/j.ejpb.2011.03.005","article-title":"Microdialysis assessment of percutaneous penetration of ketoprofen after transdermal administration to hairless rats and domestic pigs","volume":"78","author":"Shinkai","year":"2011","journal-title":"Eur. J. Pharm. Biopharm."},{"key":"10.1016\/j.jconrel.2012.05.011_bb0030","doi-asserted-by":"crossref","first-page":"306","DOI":"10.1111\/j.1365-2133.2008.08683.x","article-title":"Skin application of the nonsteroidal anti-inflammatory drug ketoprofen downmodulates the antigen-presenting ability of Langerhans cells in mice","volume":"159","author":"Atarashi","year":"2008","journal-title":"Br. J. Dermatol."},{"key":"10.1016\/j.jconrel.2012.05.011_bb0035","doi-asserted-by":"crossref","first-page":"19","DOI":"10.1111\/j.2042-7158.2004.tb02573.x","article-title":"Preformulation stability of Spantide II, a promising topical anti-inflammatory agent for the treatment of psoriasis and contact dermatitis","volume":"56","author":"Kikwai","year":"2004","journal-title":"J. Pharm. Pharmacol."},{"key":"10.1016\/j.jconrel.2012.05.011_bb0040","doi-asserted-by":"crossref","first-page":"36","DOI":"10.1016\/j.ejpb.2011.04.009","article-title":"Lipid nanocapsules for dermal application: a comparative study of lipid-based versus polymer-based nanocarriers","volume":"79","author":"Abdel-Mottaleb","year":"2011","journal-title":"Eur. J. Pharm. Biopharm."},{"key":"10.1016\/j.jconrel.2012.05.011_bb0045","doi-asserted-by":"crossref","first-page":"85","DOI":"10.1016\/j.jconrel.2006.07.001","article-title":"Insights into synergistic interactions in binary mixtures of chemical permeation enhancers for transdermal drug delivery","volume":"115","author":"Karande","year":"2006","journal-title":"J. Control. Release"},{"key":"10.1016\/j.jconrel.2012.05.011_bb0050","doi-asserted-by":"crossref","first-page":"85","DOI":"10.1016\/0168-3659(87)90066-6","article-title":"Mode of action of penetration enhancers in human skin","volume":"6","author":"Barry","year":"1987","journal-title":"J. Control. Release"},{"key":"10.1016\/j.jconrel.2012.05.011_bb0055","doi-asserted-by":"crossref","first-page":"330","DOI":"10.1016\/j.jconrel.2011.01.006","article-title":"Ultrasound-mediated transdermal drug delivery: mechanisms, scope, and emerging trends","volume":"152","author":"Polat","year":"2011","journal-title":"J. Control. Release"},{"key":"10.1016\/j.jconrel.2012.05.011_bb0060","doi-asserted-by":"crossref","first-page":"311","DOI":"10.1016\/S0168-3659(03)00123-8","article-title":"Radiofrequency-driven skin microchanneling as a new way for electrically assisted transdermal delivery of hydrophilic drugs","volume":"89","author":"Sintov","year":"2003","journal-title":"J. Control. Release"},{"key":"10.1016\/j.jconrel.2012.05.011_bb0065","doi-asserted-by":"crossref","first-page":"123","DOI":"10.1016\/j.jconrel.2009.03.018","article-title":"A fast screening strategy for characterizing peptide delivery by transdermal iontophoresis","volume":"137","author":"Henchoz","year":"2009","journal-title":"J. Control. Release"},{"key":"10.1016\/j.jconrel.2012.05.011_bb0070","doi-asserted-by":"crossref","first-page":"63","DOI":"10.1016\/j.jconrel.2009.05.031","article-title":"Iontophoresis-driven penetration of nanovesicles through microneedle-induced skin microchannels for enhancing transdermal delivery of insulin","volume":"139","author":"Chen","year":"2009","journal-title":"J. Control. Release"},{"key":"10.1016\/j.jconrel.2012.05.011_bb0075","doi-asserted-by":"crossref","first-page":"197","DOI":"10.1016\/j.jconrel.2010.08.015","article-title":"Magnetophoresis for enhancing transdermal drug delivery: mechanistic studies and patch design","volume":"148","author":"Murthy","year":"2010","journal-title":"J. Control. Release"},{"key":"10.1016\/j.jconrel.2012.05.011_bb0080","doi-asserted-by":"crossref","first-page":"225","DOI":"10.1016\/S0168-3659(97)00147-8","article-title":"Transdermal delivery of fentanyl: rapid onset of analgesia using skin electroporation","volume":"50","author":"Vanbever","year":"1998","journal-title":"J. Control. Release"},{"key":"10.1016\/j.jconrel.2012.05.011_bb0085","doi-asserted-by":"crossref","first-page":"218","DOI":"10.1016\/j.jconrel.2010.07.104","article-title":"Influence of microneedle shape on the transport of a fluorescent dye into human skin in vivo","volume":"147","author":"Bal","year":"2010","journal-title":"J. Control. Release"},{"key":"10.1016\/j.jconrel.2012.05.011_bb0090","doi-asserted-by":"crossref","first-page":"277","DOI":"10.1016\/j.jconrel.2009.10.016","article-title":"Nanotechnology and the transdermal route: a state of the art review and critical appraisal","volume":"141","author":"Cevc","year":"2010","journal-title":"J. Control. Release"},{"key":"10.1016\/j.jconrel.2012.05.011_bb0095","doi-asserted-by":"crossref","first-page":"247","DOI":"10.3109\/09687688.2010.522203","article-title":"Interaction of nanoparticles and cell-penetrating peptides with skin for transdermal drug delivery","volume":"27","author":"Desai","year":"2010","journal-title":"Mol. Membr. Biol."},{"key":"10.1016\/j.jconrel.2012.05.011_bb0100","doi-asserted-by":"crossref","first-page":"267","DOI":"10.1016\/j.ijpharm.2011.05.008","article-title":"Lipid nanocarriers for dermal delivery of lutein: preparation, characterization, stability and performance","volume":"414","author":"Mitri","year":"2011","journal-title":"Int. J. Pharm."},{"key":"10.1016\/j.jconrel.2012.05.011_bb0105","doi-asserted-by":"crossref","first-page":"427","DOI":"10.1016\/j.addr.2007.04.006","article-title":"Lipid nanoparticles for improved topical application of drugs for skin diseases","volume":"59","author":"Schafer-Korting","year":"2007","journal-title":"Adv. Drug Deliv. Rev."},{"key":"10.1016\/j.jconrel.2012.05.011_bb0110","doi-asserted-by":"crossref","first-page":"165","DOI":"10.1016\/j.ijpharm.2010.07.008","article-title":"Targeting tacrolimus to deeper layers of skin with improved safety for treatment of atopic dermatitis","volume":"398","author":"Pople","year":"2010","journal-title":"Int. J. Pharm."},{"key":"10.1016\/j.jconrel.2012.05.011_bb0115","doi-asserted-by":"crossref","first-page":"134","DOI":"10.1016\/j.jconrel.2008.02.011","article-title":"Influence of oil content on physicochemical properties and skin distribution of nile red-loaded NLC","volume":"128","author":"Teeranachaideekul","year":"2008","journal-title":"J. Control. Release"},{"key":"10.1016\/j.jconrel.2012.05.011_bb0120","doi-asserted-by":"crossref","first-page":"5598","DOI":"10.1016\/j.biomaterials.2010.03.010","article-title":"Translocation of cell penetrating peptide engrafted nanoparticles across skin layers","volume":"31","author":"Patlolla","year":"2010","journal-title":"Biomaterials"},{"key":"10.1016\/j.jconrel.2012.05.011_bb0125","doi-asserted-by":"crossref","first-page":"953","DOI":"10.1016\/j.addr.2009.06.001","article-title":"Recent advances in the use of cell-penetrating peptides for medical and biological applications","volume":"61","author":"Fonseca","year":"2009","journal-title":"Adv. Drug Deliv. Rev."},{"key":"10.1016\/j.jconrel.2012.05.011_bb0130","doi-asserted-by":"crossref","first-page":"256","DOI":"10.1016\/j.jconrel.2011.01.018","article-title":"Noninvasive and efficient transdermal delivery of CpG-oligodeoxynucleotide for cancer immunotherapy","volume":"150","author":"Kigasawa","year":"2011","journal-title":"J. Control. Release"},{"key":"10.1016\/j.jconrel.2012.05.011_bb0135","doi-asserted-by":"crossref","first-page":"131","DOI":"10.1016\/j.colsurfb.2010.01.013","article-title":"H(II) mesophase and peptide cell-penetrating enhancers for improved transdermal delivery of sodium diclofenac","volume":"77","author":"Cohen-Avrahami","year":"2010","journal-title":"Colloids Surf. B Biointerfaces"},{"key":"10.1016\/j.jconrel.2012.05.011_bb0140","doi-asserted-by":"crossref","first-page":"10189","DOI":"10.1021\/jp112067v","article-title":"Sodium diclofenac and cell-penetrating peptides embedded in H(II) mesophases: physical characterization and delivery","volume":"115","author":"Cohen-Avrahami","year":"2011","journal-title":"J. Phys. Chem. B"},{"key":"10.1016\/j.jconrel.2012.05.011_bb0145","doi-asserted-by":"crossref","first-page":"547","DOI":"10.1016\/j.addr.2004.10.009","article-title":"Membrane-permeable arginine-rich peptides and the translocation mechanisms","volume":"57","author":"Futaki","year":"2005","journal-title":"Adv. Drug Deliv. Rev."},{"key":"10.1016\/j.jconrel.2012.05.011_bb0150","doi-asserted-by":"crossref","first-page":"582","DOI":"10.1016\/j.jconrel.2012.04.003","article-title":"Cell entry of cell penetrating peptides: tales of tails wagging dogs","volume":"161","author":"Jones","year":"2012","journal-title":"J. Control. Release"},{"key":"10.1016\/j.jconrel.2012.05.011_bb0155","doi-asserted-by":"crossref","first-page":"67","DOI":"10.1016\/j.ejpb.2011.08.002","article-title":"Quality by design approach for developing chitosan-Ca-alginate microspheres for colon delivery of celecoxib-hydroxypropyl-\u03b2-cyclodextrin\u2013PVP complex","volume":"80","author":"Mennini","year":"2012","journal-title":"Eur. J. Pharm. Biopharm."},{"key":"10.1016\/j.jconrel.2012.05.011_bb0160","doi-asserted-by":"crossref","first-page":"690","DOI":"10.1002\/jps.21456","article-title":"Influence of chitosan crosslinking on bitterness of mefloquine hydrochloride microparticles using central composite design","volume":"98","author":"Shah","year":"2009","journal-title":"J. Pharm. Sci."},{"key":"10.1016\/j.jconrel.2012.05.011_bb0165","doi-asserted-by":"crossref","first-page":"379","DOI":"10.2478\/v10007-008-0027-y","article-title":"Design and optimization of artemether microparticles for bitter taste masking","volume":"58","author":"Shah","year":"2008","journal-title":"Acta Pharm."},{"key":"10.1016\/j.jconrel.2012.05.011_bb0170","doi-asserted-by":"crossref","first-page":"49","DOI":"10.1016\/S0168-3659(02)00368-1","article-title":"The influence of various methods of cold storage of skin on the permeation of melatonin and nimesulide","volume":"86","author":"Babu","year":"2003","journal-title":"J. Control. Release"},{"key":"10.1016\/j.jconrel.2012.05.011_bb0175","doi-asserted-by":"crossref","first-page":"1764","DOI":"10.1007\/s11095-009-9888-0","article-title":"Nanoparticle coated submicron emulsions: sustained in-vitro release and improved dermal delivery of all-trans-retinol","volume":"26","author":"Ghouchi Eskandar","year":"2009","journal-title":"Pharm. Res."},{"key":"10.1016\/j.jconrel.2012.05.011_bb0180","doi-asserted-by":"crossref","first-page":"1607","DOI":"10.1016\/j.biomaterials.2011.11.011","article-title":"Skin permeating nanogel for the cutaneous co-delivery of two anti-inflammatory drugs","volume":"33","author":"Shah","year":"2012","journal-title":"Biomaterials"},{"key":"10.1016\/j.jconrel.2012.05.011_bb0185","doi-asserted-by":"crossref","first-page":"336","DOI":"10.1016\/j.jconrel.2011.11.016","article-title":"Effect of oleic acid modified polymeric bilayered nanoparticles on percutaneous delivery of spantide II and ketoprofen","volume":"158","author":"Shah","year":"2011","journal-title":"J. Control. Release"},{"key":"10.1016\/j.jconrel.2012.05.011_bb0190","doi-asserted-by":"crossref","first-page":"271","DOI":"10.1016\/j.lungcan.2010.06.002","article-title":"Anticancer activity of noscapine, an opioid alkaloid in combination with cisplatin in human non-small cell lung cancer","volume":"71","author":"Chougule","year":"2012","journal-title":"Lung Cancer"},{"key":"10.1016\/j.jconrel.2012.05.011_bb0195","doi-asserted-by":"crossref","first-page":"459","DOI":"10.1208\/s12249-009-9231-4","article-title":"Development and evaluation of sustained release gastroretentive minimatrices for effective treatment of H. pylori infection","volume":"10","author":"Badhan","year":"2009","journal-title":"AAPS PharmSciTech"},{"key":"10.1016\/j.jconrel.2012.05.011_bb0200","doi-asserted-by":"crossref","first-page":"157","DOI":"10.1111\/j.1468-2494.2008.00433.x","article-title":"Cosmetic features and applications of lipid nanoparticles (SLN, NLC)","volume":"30","author":"Souto","year":"2008","journal-title":"Int. J. Cosmet. Sci."},{"key":"10.1016\/j.jconrel.2012.05.011_bb0205","doi-asserted-by":"crossref","first-page":"23","DOI":"10.1016\/j.ejpb.2011.03.021","article-title":"Drug delivery into the skin by degradable particles","volume":"79","author":"Mak","year":"2011","journal-title":"Eur. J. Pharm. Biopharm."},{"key":"10.1016\/j.jconrel.2012.05.011_bb0210","doi-asserted-by":"crossref","first-page":"196","DOI":"10.1248\/cpb.59.196","article-title":"Development of an efficient transdermal delivery system of small interfering RNA using functional peptides, Tat and AT-1002","volume":"59","author":"Uchida","year":"2011","journal-title":"Chem. Pharm. Bull.(Tokyo)"},{"key":"10.1016\/j.jconrel.2012.05.011_bb0215","doi-asserted-by":"crossref","first-page":"419","DOI":"10.1016\/j.jconrel.2012.01.025","article-title":"Penetratin-induced transdermal delivery from H(II) mesophases of sodium diclofenac","volume":"159","author":"Cohen-Avrahami","year":"2012","journal-title":"J. Control. Release"},{"key":"10.1016\/j.jconrel.2012.05.011_bb0220","doi-asserted-by":"crossref","first-page":"15816","DOI":"10.1073\/pnas.1016152108","article-title":"Delivery of siRNA and other macromolecules into skin and cells using a peptide enhancer","volume":"108","author":"Hsu","year":"2011","journal-title":"Proc. Natl. Acad. Sci. U.S.A."},{"key":"10.1016\/j.jconrel.2012.05.011_bb0225","doi-asserted-by":"crossref","first-page":"173","DOI":"10.1016\/j.ejpb.2008.11.001","article-title":"Follicular transport route\u2014research progress and future perspectives","volume":"71","author":"Knorr","year":"2009","journal-title":"Eur. J. Pharm. Biopharm."},{"key":"10.1016\/j.jconrel.2012.05.011_bb0230","doi-asserted-by":"crossref","first-page":"318","DOI":"10.1034\/j.1399-3011.2000.00723.x","article-title":"Polyarginine enters cells more efficiently than other polycationic homopolymers","volume":"56","author":"Mitchell","year":"2000","journal-title":"J. Pept. Res."},{"key":"10.1016\/j.jconrel.2012.05.011_bb0235","doi-asserted-by":"crossref","first-page":"E573","DOI":"10.1208\/pt060472","article-title":"Box-Behnken experimental design in the development of a nasal drug delivery system of model drug hydroxyurea: characterization of viscosity, in vitro drug release, droplet size, and dynamic surface tension","volume":"6","author":"Dayal","year":"2005","journal-title":"AAPS PharmSciTech"},{"key":"10.1016\/j.jconrel.2012.05.011_bb0240","doi-asserted-by":"crossref","first-page":"421","DOI":"10.1211\/jpp.60.4.0003","article-title":"Effect of chitosan crosslinking on bitterness of artemether using response surface methodology","volume":"60","author":"Shah","year":"2008","journal-title":"J. Pharm. Pharmacol."},{"key":"10.1016\/j.jconrel.2012.05.011_bb0245","doi-asserted-by":"crossref","first-page":"1008","DOI":"10.1080\/03639040601179749","article-title":"Investigations on factors affecting chitosan for dissolution enhancement of oxcarbazepine by spray dried microcrystal formulation with an experimental design approach","volume":"33","author":"Rane","year":"2007","journal-title":"Drug Dev. Ind. Pharm."},{"key":"10.1016\/j.jconrel.2012.05.011_bb0250","doi-asserted-by":"crossref","first-page":"377","DOI":"10.1208\/s12249-008-9052-x","article-title":"Design and optimization of mefloquine hydrochloride microparticles for bitter taste masking","volume":"9","author":"Shah","year":"2008","journal-title":"AAPS PharmSciTech"},{"key":"10.1016\/j.jconrel.2012.05.011_bb0255","doi-asserted-by":"crossref","first-page":"158","DOI":"10.1016\/j.ejps.2005.09.005","article-title":"Stability and degradation profiles of spantide II in aqueous solutions","volume":"27","author":"Kikwai","year":"2006","journal-title":"Eur. J. Pharm. Sci."},{"key":"10.1016\/j.jconrel.2012.05.011_bb0260","doi-asserted-by":"crossref","first-page":"47","DOI":"10.1016\/S0378-5173(03)00229-1","article-title":"Physical and thermal characterisation of precirol and compritol as lipophilic glycerides used for the preparation of controlled-release matrix pellets","volume":"260","author":"Hamdani","year":"2003","journal-title":"Int. J. Pharm."},{"key":"10.1016\/j.jconrel.2012.05.011_bb0265","doi-asserted-by":"crossref","first-page":"171","DOI":"10.1016\/j.ejphar.2010.07.031","article-title":"Comparison of the efficacy of tacrolimus and cyclosporine A in a murine model of dinitrofluorobenzene-induced atopic dermatitis","volume":"645","author":"Yamashita","year":"2010","journal-title":"Eur. J. Pharmacol."},{"key":"10.1016\/j.jconrel.2012.05.011_bb0270","doi-asserted-by":"crossref","first-page":"477","DOI":"10.1067\/S0190-9622(03)01826-7","article-title":"Tacrolimus ointment 0.1% in the treatment of nickel-induced allergic contact dermatitis","volume":"49","author":"Saripalli","year":"2003","journal-title":"J. Am. Acad. Dermatol."},{"key":"10.1016\/j.jconrel.2012.05.011_bb0275","doi-asserted-by":"crossref","first-page":"40","DOI":"10.1016\/j.jaad.2006.03.025","article-title":"A prospective randomized clinical trial of 0.1% tacrolimus ointment in a model of chronic allergic contact dermatitis","volume":"55","author":"Belsito","year":"2006","journal-title":"J. Am. Acad. Dermatol."}],"container-title":["Journal of Controlled Release"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0168365912003392?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0168365912003392?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,9,29]],"date-time":"2025-09-29T15:26:26Z","timestamp":1759159586000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0168365912003392"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2012,8]]},"references-count":55,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2012,8]]}},"alternative-id":["S0168365912003392"],"URL":"https:\/\/doi.org\/10.1016\/j.jconrel.2012.05.011","relation":{},"ISSN":["0168-3659"],"issn-type":[{"value":"0168-3659","type":"print"}],"subject":[],"published":{"date-parts":[[2012,8]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Enhanced skin permeation using polyarginine modified nanostructured lipid carriers","name":"articletitle","label":"Article Title"},{"value":"Journal of Controlled Release","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.jconrel.2012.05.011","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2012 Elsevier B.V. All rights reserved.","name":"copyright","label":"Copyright"}]}}