{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,5]],"date-time":"2026-07-05T16:47:21Z","timestamp":1783270041554,"version":"3.54.6"},"reference-count":18,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2016,7,1]],"date-time":"2016-07-01T00:00:00Z","timestamp":1467331200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Journal of Controlled Release"],"published-print":{"date-parts":[[2016,7]]},"DOI":"10.1016\/j.jconrel.2016.05.019","type":"journal-article","created":{"date-parts":[[2016,5,10]],"date-time":"2016-05-10T13:18:40Z","timestamp":1462886320000},"page":"98-103","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":37,"special_numbering":"C","title":["Penetration and delivery characteristics of repetitive microjet injection into the skin"],"prefix":"10.1016","volume":"234","author":[{"given":"Anne M.","family":"R\u00f6mgens","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Debbie","family":"Rem-Bronneberg","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Roel","family":"Kassies","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Markus","family":"Hijlkema","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dan L.","family":"Bader","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Cees W.J.","family":"Oomens","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michel P.B.","family":"van Bruggen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.jconrel.2016.05.019_bb0005","doi-asserted-by":"crossref","first-page":"4255","DOI":"10.1073\/pnas.0700182104","article-title":"Needle-free delivery of macromolecules across the skin by nanoliter-volume pulsed microjets","volume":"104","author":"Arora","year":"2007","journal-title":"Proc. Natl. Acad. Sci."},{"key":"10.1016\/j.jconrel.2016.05.019_bb0010","doi-asserted-by":"crossref","first-page":"361","DOI":"10.1016\/j.jconrel.2005.05.023","article-title":"Jet-induced skin puncture and its impact on needle-free jet injections: experimental studies and a predictive model","volume":"106","author":"Baxter","year":"2005","journal-title":"J. Control. Release"},{"key":"10.1016\/j.jconrel.2016.05.019_bb0015","doi-asserted-by":"crossref","first-page":"1176","DOI":"10.1016\/j.jbiomech.2012.01.049","article-title":"Prestress as an optimal biomechanical parameter for needle penetration","volume":"45","author":"Butz","year":"2012","journal-title":"J. Biomech."},{"key":"10.1016\/j.jconrel.2016.05.019_bb0020","series-title":"Skin layer mechanics","author":"Geerligs","year":"2010"},{"key":"10.1016\/j.jconrel.2016.05.019_bb0025","doi-asserted-by":"crossref","first-page":"118002","DOI":"10.1117\/1.JBO.19.11.118002","article-title":"Laser-induced microjet injection into preablated skin for more effective transdermal drug delivery","volume":"19","author":"Jang","year":"2014","journal-title":"J. Biomed. Opt."},{"key":"10.1016\/j.jconrel.2016.05.019_bb0030","doi-asserted-by":"crossref","first-page":"249","DOI":"10.1016\/j.jconrel.2011.03.024","article-title":"Delivery of polymeric particles into skin using needle-free liquid jet injectors","volume":"153","author":"Michinaka","year":"2011","journal-title":"J. Control. Release"},{"key":"10.1016\/j.jconrel.2016.05.019_bb0035","doi-asserted-by":"crossref","first-page":"543","DOI":"10.1038\/nrd2076","article-title":"Current status and future prospects of needle-free liquid jet injectors","volume":"5","author":"Mitragotri","year":"2006","journal-title":"Nat. Rev. Drug Discov."},{"key":"10.1016\/j.jconrel.2016.05.019_bb0040","doi-asserted-by":"crossref","first-page":"2515","DOI":"10.2147\/DDDT.S79885","article-title":"Impact of streptozotocin on altering normal glucose homeostasis during insulin testing in diabetic rats compared to normoglycemic rats","volume":"9","author":"Qinna","year":"2015","journal-title":"Drug Des Devel Ther."},{"key":"10.1016\/j.jconrel.2016.05.019_bb0045","doi-asserted-by":"crossref","first-page":"307","DOI":"10.1016\/j.vaccine.2014.11.025","article-title":"Immune responses after fractional doses of inactivated poliovirus vaccine using newly developed intradermal jet injectors: a randomized controlled trial in Cuba","volume":"33","author":"Resik","year":"2015","journal-title":"Vaccine"},{"key":"10.1016\/j.jconrel.2016.05.019_bb0050","doi-asserted-by":"crossref","first-page":"397","DOI":"10.1016\/j.jmbbm.2014.09.015","article-title":"Monitoring the penetration process of single microneedles with varying tip diameters","volume":"40","author":"R\u00f6mgens","year":"2014","journal-title":"J. Mech. Behav. Biomed. Mater."},{"key":"10.1016\/j.jconrel.2016.05.019_bb0055","doi-asserted-by":"crossref","first-page":"1181","DOI":"10.1016\/j.jbiomech.2003.12.006","article-title":"Jet injection into polyacrylamide gels: investigation of jet injection mechanics","volume":"37","author":"Schramm-Baxter","year":"2004","journal-title":"J. Biomech."},{"key":"10.1016\/j.jconrel.2016.05.019_bb0060","doi-asserted-by":"crossref","first-page":"527","DOI":"10.1016\/j.jconrel.2004.04.006","article-title":"Needle-free jet injections: dependence of jet penetration and dispersion in the skin on jet power","volume":"97","author":"Schramm-Baxter","year":"2004","journal-title":"J. Control. Release"},{"key":"10.1016\/j.jconrel.2016.05.019_bb0065","doi-asserted-by":"crossref","first-page":"2593","DOI":"10.1016\/j.jbiomech.2005.08.028","article-title":"The penetration of a soft solid by a liquid jet, with application to the administration of a needle-free injection","volume":"39","author":"Shergold","year":"2006","journal-title":"J. Biomech."},{"key":"10.1016\/j.jconrel.2016.05.019_bb0070","doi-asserted-by":"crossref","first-page":"104","DOI":"10.1016\/j.jconrel.2009.01.003","article-title":"Dynamic control of needle-free jet injection","volume":"135","author":"Stachowiak","year":"2009","journal-title":"J. Control. Release"},{"key":"10.1016\/j.jconrel.2016.05.019_bb0075","doi-asserted-by":"crossref","first-page":"88","DOI":"10.1016\/j.jconrel.2007.08.017","article-title":"Piezoelectric control of needle-free transdermal drug delivery","volume":"124","author":"Stachowiak","year":"2007","journal-title":"J. Control. Release"},{"key":"10.1016\/j.jconrel.2016.05.019_bb0080","doi-asserted-by":"crossref","first-page":"287","DOI":"10.1111\/1523-1747.ep12277593","article-title":"Dispase, a neutral protease from bacillus polymyxa, is a powerful fibronectinase and type IV collagenase","volume":"93","author":"Stenn","year":"1989","journal-title":"J. Investig. Dermatol."},{"key":"10.1016\/j.jconrel.2016.05.019_bb0085","doi-asserted-by":"crossref","first-page":"1228","DOI":"10.1016\/j.medengphy.2011.12.010","article-title":"Needle-free jet injection using real-time controlled linear Lorentz-force actuators","volume":"34","author":"Taberner","year":"2012","journal-title":"Med. Eng. Phys."},{"key":"10.1016\/j.jconrel.2016.05.019_bb0090","doi-asserted-by":"crossref","first-page":"1357","DOI":"10.1039\/c2lc41204g","article-title":"Needle-free injection into skin and soft matter with highly focused microjets","volume":"13","author":"Tagawa","year":"2013","journal-title":"Lab Chip"}],"container-title":["Journal of Controlled Release"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S016836591630284X?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S016836591630284X?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2019,10,30]],"date-time":"2019-10-30T08:51:54Z","timestamp":1572425514000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S016836591630284X"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2016,7]]},"references-count":18,"alternative-id":["S016836591630284X"],"URL":"https:\/\/doi.org\/10.1016\/j.jconrel.2016.05.019","relation":{},"ISSN":["0168-3659"],"issn-type":[{"value":"0168-3659","type":"print"}],"subject":[],"published":{"date-parts":[[2016,7]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Penetration and delivery characteristics of repetitive microjet injection into the skin","name":"articletitle","label":"Article Title"},{"value":"Journal of Controlled Release","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.jconrel.2016.05.019","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2016 Elsevier B.V. All rights reserved.","name":"copyright","label":"Copyright"}]}}