{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,12]],"date-time":"2026-05-12T07:43:52Z","timestamp":1778571832064,"version":"3.51.4"},"reference-count":56,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2017,11,1]],"date-time":"2017-11-01T00:00:00Z","timestamp":1509494400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"funder":[{"DOI":"10.13039\/100007859","name":"University of Kansas","doi-asserted-by":"crossref","award":["T32-GM008359"],"award-info":[{"award-number":["T32-GM008359"]}],"id":[{"id":"10.13039\/100007859","id-type":"DOI","asserted-by":"crossref"}]},{"DOI":"10.13039\/100000002","name":"NIH","doi-asserted-by":"publisher","award":["T32 GM008545"],"award-info":[{"award-number":["T32 GM008545"]}],"id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Journal of Controlled Release"],"published-print":{"date-parts":[[2017,11]]},"DOI":"10.1016\/j.jconrel.2017.09.034","type":"journal-article","created":{"date-parts":[[2017,9,28]],"date-time":"2017-09-28T03:18:24Z","timestamp":1506568704000},"page":"156-165","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":14,"special_numbering":"C","title":["Co-delivery of autoantigen and dexamethasone in incomplete Freund's adjuvant ameliorates experimental autoimmune encephalomyelitis"],"prefix":"10.1016","volume":"266","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-1216-1998","authenticated-orcid":false,"given":"Laura","family":"Northrup","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"J. Daniel","family":"Griffin","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Matthew A.","family":"Christopher","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lorena R.","family":"Antunez","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Brittany L.","family":"Hartwell","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Chad J.","family":"Pickens","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Cory","family":"Berkland","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.jconrel.2017.09.034_bb0005","doi-asserted-by":"crossref","first-page":"181","DOI":"10.1146\/annurev-bioeng-110315-020137","article-title":"Immune tolerance for autoimmune disease and cell transplantation","volume":"18","author":"Luo","year":"2016","journal-title":"Annu. Rev. Biomed. Eng."},{"key":"10.1016\/j.jconrel.2017.09.034_bb0010","doi-asserted-by":"crossref","first-page":"239","DOI":"10.1002\/ana.21640","article-title":"The challenge of multiple sclerosis: how do we cure a chronic heterogeneous disease?","volume":"65","author":"Weiner","year":"2009","journal-title":"Ann. Neurol."},{"key":"10.1016\/j.jconrel.2017.09.034_bb0015","doi-asserted-by":"crossref","first-page":"1167","DOI":"10.1038\/80516","article-title":"Encephalitogenic potential of the myelin basic protein peptide (amino acids 83\u201399) in multiple sclerosis: results of a phase II clinical trial with an altered peptide ligand","volume":"6","author":"Bielekova","year":"2000","journal-title":"Nat. Med."},{"key":"10.1016\/j.jconrel.2017.09.034_bb0020","doi-asserted-by":"crossref","first-page":"1176","DOI":"10.1038\/80525","article-title":"Induction of a non-encephalitogenic type 2 T helper-cell autoimmune response in multiple sclerosis after administration of an altered peptide ligand in a placebo-controlled, randomized phase II trial. The Altered Peptide Ligand in Relapsing MS Study Group","volume":"6","author":"Kappos","year":"2000","journal-title":"Nat. Med."},{"key":"10.1016\/j.jconrel.2017.09.034_bb0025","doi-asserted-by":"crossref","first-page":"1551","DOI":"10.1212\/WNL.0b013e318233b240","article-title":"A phase III study evaluating the efficacy and safety of MBP8298 in secondary progressive MS","volume":"77","author":"Freedman","year":"2011","journal-title":"Neurology"},{"key":"10.1016\/j.jconrel.2017.09.034_bb0030","article-title":"Combining antigen and immunomodulators: Emerging trends in antigen-specific immunotherapy for autoimmunity","author":"Northrup","year":"2015","journal-title":"Adv. Drug Deliv. Rev."},{"key":"10.1016\/j.jconrel.2017.09.034_bb0035","doi-asserted-by":"crossref","first-page":"2940","DOI":"10.1016\/j.celrep.2016.08.033","article-title":"Reprogramming the local lymph node microenvironment promotes tolerance that is systemic and antigen specific","volume":"16","author":"Tostanoski","year":"2016","journal-title":"Cell Rep."},{"key":"10.1016\/j.jconrel.2017.09.034_bb0040","doi-asserted-by":"crossref","first-page":"E156","DOI":"10.1073\/pnas.1408686111","article-title":"Polymeric synthetic nanoparticles for the induction of antigen-specific immunological tolerance","volume":"112","author":"Maldonado","year":"2015","journal-title":"Proc. Natl. Acad. Sci. U. S. A."},{"key":"10.1016\/j.jconrel.2017.09.034_bb0045","doi-asserted-by":"crossref","first-page":"828","DOI":"10.1021\/mp4005172","article-title":"Treatment of experimental autoimmune encephalomyelitis by codelivery of disease associated Peptide and dexamethasone in acetalated dextran microparticles","volume":"11","author":"Peine","year":"2014","journal-title":"Mol. Pharm."},{"key":"10.1016\/j.jconrel.2017.09.034_bb0050","doi-asserted-by":"crossref","first-page":"11270","DOI":"10.1073\/pnas.1120611109","article-title":"Nanoparticle-mediated codelivery of myelin antigen and a tolerogenic small molecule suppresses experimental autoimmune encephalomyelitis","volume":"109","author":"Yeste","year":"2012","journal-title":"Proc. Natl. Acad. Sci. U. S. A."},{"key":"10.1016\/j.jconrel.2017.09.034_bb0055","doi-asserted-by":"crossref","first-page":"3556","DOI":"10.4049\/jimmunol.0802972","article-title":"Antigen-specific suppression of inflammatory arthritis using liposomes","volume":"182","author":"Capini","year":"2009","journal-title":"J. Immunol."},{"key":"10.1016\/j.jconrel.2017.09.034_bb0060","doi-asserted-by":"crossref","first-page":"879","DOI":"10.1124\/jpet.107.123257","article-title":"Antigen-specific suppression of experimental autoimmune encephalomyelitis by a novel bifunctional peptide inhibitor","volume":"322","author":"Kobayashi","year":"2007","journal-title":"J. Pharmacol. Exp. Ther."},{"key":"10.1016\/j.jconrel.2017.09.034_bb0065","doi-asserted-by":"crossref","DOI":"10.1038\/mtm.2014.8","article-title":"Codelivery of antigen and an immune cell adhesion inhibitor is necessary for efficacy of soluble antigen arrays in experimental autoimmune encephalomyelitis","volume":"1","author":"Sestak","year":"2014","journal-title":"Mol. Therapy Methods Clin. Dev."},{"key":"10.1016\/j.jconrel.2017.09.034_bb0070","doi-asserted-by":"crossref","first-page":"1204","DOI":"10.1208\/s12248-014-9671-y","article-title":"Co-delivery of autoantigen and b7 pathway modulators suppresses experimental autoimmune encephalomyelitis","volume":"16","author":"Northrup","year":"2014","journal-title":"AAPS J."},{"key":"10.1016\/j.jconrel.2017.09.034_bb0075","doi-asserted-by":"crossref","first-page":"978","DOI":"10.1038\/nmat3775","article-title":"Engineering synthetic vaccines using cues from natural immunity","volume":"12","author":"Irvine","year":"2013","journal-title":"Nat. Mater."},{"key":"10.1016\/j.jconrel.2017.09.034_bb0080","series-title":"Kuby Immunology","author":"Kindt","year":"2007"},{"key":"10.1016\/j.jconrel.2017.09.034_bb0085","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1111\/j.1365-2249.2010.04143.x","article-title":"T cells in multiple sclerosis and experimental autoimmune encephalomyelitis","volume":"162","author":"Fletcher","year":"2010","journal-title":"Clin. Exp. Immunol."},{"key":"10.1016\/j.jconrel.2017.09.034_bb0090","doi-asserted-by":"crossref","first-page":"528","DOI":"10.1007\/s11481-015-9614-0","article-title":"Multiple sclerosis and T lymphocytes: an entangled story","volume":"10","author":"Legroux","year":"2015","journal-title":"J. NeuroImmune Pharmacol."},{"key":"10.1016\/j.jconrel.2017.09.034_bb0095","doi-asserted-by":"crossref","first-page":"5771","DOI":"10.4049\/jimmunol.164.11.5771","article-title":"Revisiting tolerance induced by autoantigen in incomplete Freund's adjuvant","volume":"164","author":"Heeger","year":"2000","journal-title":"J. Immunol."},{"key":"10.1016\/j.jconrel.2017.09.034_bb0100","doi-asserted-by":"crossref","first-page":"213","DOI":"10.1007\/s12026-011-8215-0","article-title":"A multivalent vaccine for type 1 diabetes skews T cell subsets to Th2 phenotype in NOD mice","volume":"50","author":"Lin","year":"2011","journal-title":"Immunol. Res."},{"key":"10.1016\/j.jconrel.2017.09.034_bb0105","doi-asserted-by":"crossref","first-page":"42","DOI":"10.1186\/1479-5876-4-42","article-title":"Immunological consequences of using three different clinical\/laboratory techniques of emulsifying peptide-based vaccines in incomplete Freund's adjuvant","volume":"4","author":"Koh","year":"2006","journal-title":"J. Transl. Med."},{"key":"10.1016\/j.jconrel.2017.09.034_bb0110","series-title":"Vaccine Design: The Subunit and Adjuvant Approach","author":"Powell","year":"1995"},{"key":"10.1016\/j.jconrel.2017.09.034_bb0115","first-page":"1025","article-title":"The immune response of C57bl-6 mice to protein antigens incorporated into Freund's incomplete adjuvant","volume":"27","author":"Dietrich","year":"1964","journal-title":"Pathol. Microbiol. (Basel)"},{"key":"10.1016\/j.jconrel.2017.09.034_bb0120","doi-asserted-by":"crossref","first-page":"38","DOI":"10.1016\/j.imlet.2013.11.001","article-title":"T cell-depleted splenocytes from mice pre-immunized with neuroantigen in incomplete Freund's adjuvant involved in protection from experimental autoimmune encephalomyelitis","volume":"157","author":"Zheng","year":"2014","journal-title":"Immunol. Lett."},{"key":"10.1016\/j.jconrel.2017.09.034_bb0125","doi-asserted-by":"crossref","first-page":"201","DOI":"10.1055\/s-2007-978622","article-title":"Incomplete Freund's adjuvant reduces diabetes in the non-obese diabetic mouse","volume":"32","author":"Liddi","year":"2000","journal-title":"Horm. Metab. Res."},{"key":"10.1016\/j.jconrel.2017.09.034_bb0130","doi-asserted-by":"crossref","first-page":"126","DOI":"10.1002\/art.1780360120","article-title":"Suppression of adjuvant-induced arthritis in DA rats by incomplete Freund's adjuvant","volume":"36","author":"Cannon","year":"1993","journal-title":"Arthritis Rheum."},{"key":"10.1016\/j.jconrel.2017.09.034_bb0135","doi-asserted-by":"crossref","first-page":"21","DOI":"10.1080\/08916930290005873","article-title":"Inhibitory effects of incomplete Freund's adjuvant on experimental autoimmune encephalomyelitis","volume":"35","author":"Zamora","year":"2002","journal-title":"Autoimmunity"},{"key":"10.1016\/j.jconrel.2017.09.034_bb0140","doi-asserted-by":"crossref","first-page":"5044","DOI":"10.4049\/jimmunol.1401392","article-title":"Antigen-specific immunotherapeutic vaccine for experimental autoimmune myasthenia gravis","volume":"193","author":"Luo","year":"2014","journal-title":"J. Immunol."},{"key":"10.1016\/j.jconrel.2017.09.034_bb0145","doi-asserted-by":"crossref","first-page":"1958","DOI":"10.1007\/s00125-010-1777-x","article-title":"Subcutaneous insulin B:9-23\/IFA immunisation induces Tregs that control late-stage prediabetes in NOD mice through IL-10 and IFNgamma","volume":"53","author":"Fousteri","year":"2010","journal-title":"Diabetologia"},{"key":"10.1016\/j.jconrel.2017.09.034_bb0150","doi-asserted-by":"crossref","first-page":"408","DOI":"10.1016\/j.jaut.2009.10.005","article-title":"Autoantigen-specific regulatory T cells induced in patients with type 1 diabetes mellitus by insulin B-chain immunotherapy","volume":"34","author":"Orban","year":"2010","journal-title":"J. Autoimmun."},{"key":"10.1016\/j.jconrel.2017.09.034_bb0155","doi-asserted-by":"crossref","first-page":"66","DOI":"10.1021\/acs.molpharmaceut.6b00725","article-title":"Screening immunomodulators to skew the antigen-specific autoimmune response","volume":"14","author":"Northrup","year":"2017","journal-title":"Mol. Pharm."},{"key":"10.1016\/j.jconrel.2017.09.034_bb0160","doi-asserted-by":"crossref","first-page":"1768","DOI":"10.4049\/jimmunol.164.4.1768","article-title":"Inhibition of Th1 immune response by glucocorticoids: dexamethasone selectively inhibits IL-12-induced Stat4 phosphorylation in T lymphocytes","volume":"164","author":"Franchimont","year":"2000","journal-title":"J. Immunol."},{"key":"10.1016\/j.jconrel.2017.09.034_bb0165","doi-asserted-by":"crossref","first-page":"219","DOI":"10.1002\/eji.201242468","article-title":"Dexamethasone promotes tolerance in vivo by enriching CD11clo CD40lo tolerogenic macrophages","volume":"43","author":"Zheng","year":"2013","journal-title":"Eur. J. Immunol."},{"key":"10.1016\/j.jconrel.2017.09.034_bb0170","doi-asserted-by":"crossref","first-page":"2139","DOI":"10.1002\/eji.200635873","article-title":"Glucocorticoid amplifies IL-2-dependent expansion of functional FoxP3(+)CD4(+)CD25(+) T regulatory cells in vivo and enhances their capacity to suppress EAE","volume":"36","author":"Chen","year":"2006","journal-title":"Eur. J. Immunol."},{"key":"10.1016\/j.jconrel.2017.09.034_bb0175","doi-asserted-by":"crossref","first-page":"138","DOI":"10.1196\/annals.1321.010","article-title":"Glucocorticoids and the Th1\/Th2 balance","volume":"1024","author":"Elenkov","year":"2004","journal-title":"Ann. N. Y. Acad. Sci."},{"key":"10.1016\/j.jconrel.2017.09.034_bb0180","doi-asserted-by":"crossref","first-page":"8434","DOI":"10.4049\/jimmunol.180.12.8434","article-title":"Peripheral T cells are the therapeutic targets of glucocorticoids in experimental autoimmune encephalomyelitis","volume":"180","author":"Wust","year":"2008","journal-title":"J. Immunol."},{"key":"10.1016\/j.jconrel.2017.09.034_bb0185","doi-asserted-by":"crossref","first-page":"5172","DOI":"10.4049\/jimmunol.180.8.5172","article-title":"Cutting edge: Immunosuppressant as adjuvant for tolerogenic immunization","volume":"180","author":"Kang","year":"2008","journal-title":"J. Immunol."},{"key":"10.1016\/j.jconrel.2017.09.034_bb0190","doi-asserted-by":"crossref","first-page":"71","DOI":"10.4049\/jimmunol.1500055","article-title":"CD11c-expressing B cells are located at the T cell\/B cell border in spleen and are potent APCs","volume":"195","author":"Rubtsov","year":"2015","journal-title":"J. Immunol."},{"key":"10.1016\/j.jconrel.2017.09.034_bb0195","doi-asserted-by":"crossref","first-page":"1305","DOI":"10.1182\/blood-2011-01-331462","article-title":"Toll-like receptor 7 (TLR7)-driven accumulation of a novel CD11c(+) B-cell population is important for the development of autoimmunity","volume":"118","author":"Rubtsov","year":"2011","journal-title":"Blood"},{"key":"10.1016\/j.jconrel.2017.09.034_bb0200","doi-asserted-by":"crossref","first-page":"5681","DOI":"10.1016\/j.vaccine.2014.08.016","article-title":"Subcutaneous inverse vaccination with PLGA particles loaded with a MOG peptide and IL-10 decreases the severity of experimental autoimmune encephalomyelitis","volume":"32","author":"Cappellano","year":"2014","journal-title":"Vaccine"},{"key":"10.1016\/j.jconrel.2017.09.034_bb0205","doi-asserted-by":"crossref","DOI":"10.1016\/j.clim.2015.03.023","article-title":"A combination dual-sized microparticle system modulates dendritic cells and prevents type 1 diabetes in prediabetic NOD mice","author":"Lewis","year":"2015","journal-title":"Clin. Immunol."},{"key":"10.1016\/j.jconrel.2017.09.034_bb0210","doi-asserted-by":"crossref","first-page":"222","DOI":"10.1096\/fj.12-213975","article-title":"Liposome-encapsulated peptides protect against experimental allergic encephalitis","volume":"27","author":"Belogurov","year":"2013","journal-title":"FASEB J."},{"key":"10.1016\/j.jconrel.2017.09.034_bb0215","doi-asserted-by":"crossref","first-page":"465","DOI":"10.1038\/nm.3105","article-title":"Persistent antigen at vaccination sites induces tumor-specific CD8(+) T cell sequestration, dysfunction and deletion","volume":"19","author":"Hailemichael","year":"2013","journal-title":"Nat. Med."},{"key":"10.1016\/j.jconrel.2017.09.034_bb0220","doi-asserted-by":"crossref","first-page":"751","DOI":"10.1084\/jem.20021690","article-title":"Preferential accumulation of antigen-specific effector CD4 T cells at an antigen injection site involves CD62E-dependent migration but not local proliferation","volume":"197","author":"Reinhardt","year":"2003","journal-title":"J. Exp. Med."},{"key":"10.1016\/j.jconrel.2017.09.034_bb0225","doi-asserted-by":"crossref","first-page":"609","DOI":"10.1016\/j.coi.2010.08.006","article-title":"Antigen-specific immunotherapy of autoimmune and allergic diseases","volume":"22","author":"Sabatos-Peyton","year":"2010","journal-title":"Curr. Opin. Immunol."},{"key":"10.1016\/j.jconrel.2017.09.034_bb0230","doi-asserted-by":"crossref","first-page":"594","DOI":"10.4049\/jimmunol.1102389","article-title":"cells enhance mast cell production of IL-6 via surface-bound TGF-beta","volume":"188","author":"Ganeshan","year":"2012","journal-title":"J. Immunol."},{"key":"10.1016\/j.jconrel.2017.09.034_bb0235","doi-asserted-by":"crossref","first-page":"950","DOI":"10.1038\/ni1497","article-title":"Development, cytokine profile and function of human interleukin 17-producing helper T cells","volume":"8","author":"Wilson","year":"2007","journal-title":"Nat. Immunol."},{"key":"10.1016\/j.jconrel.2017.09.034_bb0240","doi-asserted-by":"crossref","first-page":"799","DOI":"10.1093\/intimm\/9.5.799","article-title":"Experimental autoimmune encephalomyelitis in IL-4-deficient mice","volume":"9","author":"Liblau","year":"1997","journal-title":"Int. Immunol."},{"key":"10.1016\/j.jconrel.2017.09.034_bb0245","doi-asserted-by":"crossref","first-page":"218","DOI":"10.3389\/fimmu.2012.00218","article-title":"Tolerogenic dendritic cells and negative vaccination in transplantation: from rodents to clinical trials","volume":"3","author":"Moreau","year":"2012","journal-title":"Front. Immunol."},{"key":"10.1016\/j.jconrel.2017.09.034_bb0250","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.jaut.2015.07.011","article-title":"Regulatory dendritic cells in autoimmunity: a comprehensive review","volume":"63","author":"Liu","year":"2015","journal-title":"J. Autoimmun."},{"key":"10.1016\/j.jconrel.2017.09.034_bb0255","doi-asserted-by":"crossref","first-page":"477","DOI":"10.1046\/j.1440-1711.2002.01115.x","article-title":"Immature, but not inactive: the tolerogenic function of immature dendritic cells","volume":"80","author":"Mahnke","year":"2002","journal-title":"Immunol. Cell Biol."},{"key":"10.1016\/j.jconrel.2017.09.034_bb0260","doi-asserted-by":"crossref","first-page":"128","DOI":"10.1186\/1479-5876-11-128","article-title":"A short protocol using dexamethasone and monophosphoryl lipid A generates tolerogenic dendritic cells that display a potent migratory capacity to lymphoid chemokines","volume":"11","author":"Garcia-Gonzalez","year":"2013","journal-title":"J. Transl. Med."},{"key":"10.1016\/j.jconrel.2017.09.034_bb0265","doi-asserted-by":"crossref","first-page":"85","DOI":"10.1002\/eji.201242879","article-title":"Tolerogenic dendritic cells impede priming of naive CD8(+) T cells and deplete memory CD8(+) T cells","volume":"43","author":"Kleijwegt","year":"2013","journal-title":"Eur. J. Immunol."},{"key":"10.1016\/j.jconrel.2017.09.034_bb0270","doi-asserted-by":"crossref","first-page":"1451","DOI":"10.1097\/01.tp.0000208801.51222.bd","article-title":"Dendritic cells activated by lipopolysaccharide after dexamethasone treatment induce donor-specific allograft hyporesponsiveness","volume":"81","author":"Emmer","year":"2006","journal-title":"Transplantation"},{"key":"10.1016\/j.jconrel.2017.09.034_bb0275","doi-asserted-by":"crossref","first-page":"6","DOI":"10.1016\/j.imlet.2009.09.006","article-title":"B cell activation versus anergy; the antigen receptor as a molecular switch","volume":"128","author":"Cambier","year":"2010","journal-title":"Immunol. Lett."},{"key":"10.1016\/j.jconrel.2017.09.034_bb0280","doi-asserted-by":"crossref","first-page":"1160","DOI":"10.1038\/ni1256","article-title":"Maintenance of B cell anergy requires constant antigen receptor occupancy and signaling","volume":"6","author":"Gauld","year":"2005","journal-title":"Nat. Immunol."}],"container-title":["Journal of Controlled Release"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0168365917308684?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0168365917308684?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2018,8,27]],"date-time":"2018-08-27T03:31:22Z","timestamp":1535340682000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0168365917308684"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2017,11]]},"references-count":56,"alternative-id":["S0168365917308684"],"URL":"https:\/\/doi.org\/10.1016\/j.jconrel.2017.09.034","relation":{},"ISSN":["0168-3659"],"issn-type":[{"value":"0168-3659","type":"print"}],"subject":[],"published":{"date-parts":[[2017,11]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Co-delivery of autoantigen and dexamethasone in incomplete Freund's adjuvant ameliorates experimental autoimmune encephalomyelitis","name":"articletitle","label":"Article Title"},{"value":"Journal of Controlled Release","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.jconrel.2017.09.034","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2017 Elsevier B.V. All rights reserved.","name":"copyright","label":"Copyright"}]}}