{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,22]],"date-time":"2026-10-22T10:37:30Z","timestamp":1792665450391,"version":"4.5.0"},"reference-count":60,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2018,5,1]],"date-time":"2018-05-01T00:00:00Z","timestamp":1525132800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Journal of Controlled Release"],"published-print":{"date-parts":[[2018,5]]},"DOI":"10.1016\/j.jconrel.2018.03.035","type":"journal-article","created":{"date-parts":[[2018,4,6]],"date-time":"2018-04-06T22:41:42Z","timestamp":1523054502000},"page":"110-121","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":120,"special_numbering":"C","title":["Preclinical evaluation of mRNA trimannosylated lipopolyplexes as therapeutic cancer vaccines targeting dendritic cells"],"prefix":"10.1016","volume":"278","author":[{"given":"A.","family":"Le Moignic","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"V.","family":"Malard","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"T.","family":"Benvegnu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"L.","family":"Lemi\u00e8gre","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"M.","family":"Berchel","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"P.-A.","family":"Jaffr\u00e8s","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"C.","family":"Baillou","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"M.","family":"Delost","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"R.","family":"Macedo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"J.","family":"Rochefort","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"G.","family":"Lescaille","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"C.","family":"Pichon","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"F.M.","family":"Lemoine","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"P.","family":"Midoux","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"V.","family":"Mateo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.jconrel.2018.03.035_bb0005","doi-asserted-by":"crossref","first-page":"37","DOI":"10.3390\/vaccines4040037","article-title":"Is there still room for cancer vaccines at the era of checkpoint inhibitors","volume":"4","author":"Karaki","year":"2016","journal-title":"Vaccine"},{"key":"10.1016\/j.jconrel.2018.03.035_bb0010","doi-asserted-by":"crossref","first-page":"74","DOI":"10.1038\/cr.2016.157","article-title":"Dendritic cell-based immunotherapy","volume":"27","author":"Sabado","year":"2017","journal-title":"Cell Res."},{"key":"10.1016\/j.jconrel.2018.03.035_bb0015","doi-asserted-by":"crossref","first-page":"363","DOI":"10.1016\/S0065-230X(07)99006-5","article-title":"Dendritic cells in cancer immunotherapy","volume":"99","author":"Vulink","year":"2008","journal-title":"Adv. Cancer Res."},{"key":"10.1016\/j.jconrel.2018.03.035_bb0020","doi-asserted-by":"crossref","first-page":"74","DOI":"10.1038\/cr.2016.157","article-title":"Dendritic cell-based immunotherapy","volume":"27","author":"Sabado","year":"2017","journal-title":"Cell Res."},{"key":"10.1016\/j.jconrel.2018.03.035_bb0025","doi-asserted-by":"crossref","first-page":"396","DOI":"10.1016\/j.coi.2013.05.001","article-title":"Human dendritic cell subsets in vaccination","volume":"25","author":"Palucka","year":"2013","journal-title":"Curr. Opin. Immunol."},{"key":"10.1016\/j.jconrel.2018.03.035_bb0030","doi-asserted-by":"crossref","first-page":"464","DOI":"10.1016\/j.immuni.2010.10.007","article-title":"Designing vaccines based on biology of human dendritic cell subsets","volume":"33","author":"Palucka","year":"2010","journal-title":"Immunity"},{"key":"10.1016\/j.jconrel.2018.03.035_bb0035","doi-asserted-by":"crossref","first-page":"61","DOI":"10.3858\/emm.2009.41.2.008","article-title":"Improving vaccines by targeting antigens to dendritic cells","volume":"41","author":"Shortman","year":"2009","journal-title":"Exp. Mol. Med."},{"key":"10.1016\/j.jconrel.2018.03.035_bb0040","doi-asserted-by":"crossref","first-page":"1519","DOI":"10.1172\/JCI0215962","article-title":"Exploiting dendritic cells to improve vaccine efficacy","volume":"109","author":"Steinman","year":"2002","journal-title":"J. Clin. Invest."},{"key":"10.1016\/j.jconrel.2018.03.035_bb0045","doi-asserted-by":"crossref","first-page":"990","DOI":"10.1038\/mt.2010.289","article-title":"Intradermal vaccinations with RNA coding for TAA generate CD8+ and CD4+ immune responses and induce clinical benefit in vaccinated patients","volume":"19","author":"Rittig","year":"2011","journal-title":"Mol. Ther. J. Am. Soc. Gene Ther."},{"issue":"32","key":"10.1016\/j.jconrel.2018.03.035_bb0050","doi-asserted-by":"crossref","first-page":"498","DOI":"10.1097\/CJI.0b013e3181a00068","article-title":"Direct injection of protamine-protected mRNA: results of a phase 1\/2 vaccination trial in metastatic melanoma patients","volume":"1997","author":"Weide","year":"2009","journal-title":"J. Immunother. Hagerstown Md"},{"key":"10.1016\/j.jconrel.2018.03.035_bb0055","doi-asserted-by":"crossref","first-page":"221","DOI":"10.1586\/14760584.2015.986104","article-title":"Lipid-based mRNA vaccine delivery systems","volume":"14","author":"Midoux","year":"2015","journal-title":"Expert Rev. Vaccines."},{"key":"10.1016\/j.jconrel.2018.03.035_bb0060","doi-asserted-by":"crossref","first-page":"251","DOI":"10.1038\/mt.2012.202","article-title":"Type I IFN counteracts the induction of antigen-specific immune responses by lipid-based delivery of mRNA vaccines","volume":"21","author":"Pollard","year":"2013","journal-title":"Mol. Ther. J. Am. Soc. Gene Ther."},{"key":"10.1016\/j.jconrel.2018.03.035_bb0065","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1002\/1521-4141(200001)30:1<1::AID-IMMU1>3.0.CO;2-#","article-title":"In vivo application of RNA leads to induction of specific cytotoxic T lymphocytes and antibodies","volume":"30","author":"Hoerr","year":"2000","journal-title":"Eur. J. Immunol."},{"key":"10.1016\/j.jconrel.2018.03.035_bb0070","doi-asserted-by":"crossref","first-page":"2118","DOI":"10.1038\/mt.2014.133","article-title":"A cationic nanoemulsion for the delivery of next-generation RNA vaccines","volume":"22","author":"Brito","year":"2014","journal-title":"Mol. Ther. J. Am. Soc. Gene Ther."},{"key":"10.1016\/j.jconrel.2018.03.035_bb0075","doi-asserted-by":"crossref","first-page":"396","DOI":"10.1038\/nature18300","article-title":"Systemic RNA delivery to dendritic cells exploits antiviral defence for cancer immunotherapy","volume":"534","author":"Kranz","year":"2016","journal-title":"Nature"},{"key":"10.1016\/j.jconrel.2018.03.035_bb0080","doi-asserted-by":"crossref","first-page":"802","DOI":"10.1038\/sj.cgt.7701072","article-title":"mRNA-based cancer vaccine: prevention of B16 melanoma progression and metastasis by systemic injection of MART1 mRNA histidylated lipopolyplexes","volume":"14","author":"Mockey","year":"2007","journal-title":"Cancer Gene Ther."},{"key":"10.1016\/j.jconrel.2018.03.035_bb0085","doi-asserted-by":"crossref","first-page":"445","DOI":"10.1016\/j.nano.2010.12.010","article-title":"Enhancement of dendritic cells transfection in vivo and of vaccination against B16F10 melanoma with mannosylated histidylated lipopolyplexes loaded with tumor antigen messenger RNA","volume":"7","author":"Perche","year":"2011","journal-title":"Nanomed. Nanotechnol. Biol. Med."},{"key":"10.1016\/j.jconrel.2018.03.035_bb0090","doi-asserted-by":"crossref","first-page":"142","DOI":"10.1016\/j.carres.2016.10.003","article-title":"Synthesis of a trimannosylated-equipped archaeal diether lipid for the development of novel glycoliposomes","volume":"435","author":"Barbeau","year":"2016","journal-title":"Carbohydr. Res."},{"key":"10.1016\/j.jconrel.2018.03.035_bb0095","doi-asserted-by":"crossref","first-page":"533","DOI":"10.1089\/hum.2012.037","article-title":"Efficacy of DNA vaccines forming E7 recombinant retroviral virus-like particles for the treatment of human papillomavirus-induced cancers","volume":"24","author":"Lescaille","year":"2013","journal-title":"Hum. Gene Ther."},{"key":"10.1016\/j.jconrel.2018.03.035_bb0100","doi-asserted-by":"crossref","first-page":"1062","DOI":"10.1016\/j.bbrc.2005.12.105","article-title":"mRNA transfection of dendritic cells: synergistic effect of ARCA mRNA capping with poly(a) chains in cis and in trans for a high protein expression level","volume":"340","author":"Mockey","year":"2006","journal-title":"Biochem. Biophys. Res. Commun."},{"issue":"158","key":"10.1016\/j.jconrel.2018.03.035_bb0105","doi-asserted-by":"crossref","first-page":"2723","DOI":"10.4049\/jimmunol.158.6.2723","article-title":"Cloned dendritic cells can present exogenous antigens on both MHC class I and class II molecules","volume":"1950","author":"Shen","year":"1997","journal-title":"J. Immunol."},{"key":"10.1016\/j.jconrel.2018.03.035_bb0110","doi-asserted-by":"crossref","first-page":"1158","DOI":"10.1002\/jgm.769","article-title":"Lentiviral transduction of human hematopoietic cells by HIV-1- and SIV-based vectors containing a bicistronic cassette driven by various internal promoters","volume":"7","author":"Dupuy","year":"2005","journal-title":"J. Gene Med."},{"key":"10.1016\/j.jconrel.2018.03.035_bb0115","doi-asserted-by":"crossref","first-page":"3124","DOI":"10.1039\/b805226c","article-title":"Novel neutral imidazole-lipophosphoramides for transfection assays","author":"M\u00e9vel","year":"2008","journal-title":"Chem. Commun. Camb. Engl."},{"key":"10.1016\/j.jconrel.2018.03.035_bb0120","doi-asserted-by":"crossref","first-page":"1462","DOI":"10.1002\/cbic.200700727","article-title":"Synthesis and transfection activity of new cationic phosphoramidate lipids: high efficiency of an imidazolium derivative","volume":"9","author":"M\u00e9vel","year":"2008","journal-title":"Chembiochem Eur. J. Chem. Biol."},{"key":"10.1016\/j.jconrel.2018.03.035_bb0125","doi-asserted-by":"crossref","first-page":"142","DOI":"10.1016\/j.carres.2016.10.003","article-title":"Synthesis of a trimannosylated-equipped archaeal diether lipid for the development of novel glycoliposomes","volume":"435","author":"Barbeau","year":"2016","journal-title":"Carbohydr. Res."},{"key":"10.1016\/j.jconrel.2018.03.035_bb0130","doi-asserted-by":"crossref","first-page":"271","DOI":"10.1016\/j.bcmd.2003.11.004","article-title":"Efficient gene transfer into human epithelial cell lines using glycosylated cationic carriers and neutral glycosylated co-lipids","volume":"32","author":"Montier","year":"2004","journal-title":"Blood Cells Mol. Dis."},{"key":"10.1016\/j.jconrel.2018.03.035_bb0135","doi-asserted-by":"crossref","first-page":"6294","DOI":"10.1002\/ejoc.201100900","article-title":"Modular construction of fluorescent lipophosphoramidates by click chemistry","volume":"2011","author":"Berchel","year":"2011","journal-title":"Eur. J. Org. Chem."},{"key":"10.1016\/j.jconrel.2018.03.035_bb0140","doi-asserted-by":"crossref","first-page":"525","DOI":"10.1016\/0003-2697(88)90578-7","article-title":"Colorimetric determination of neutral sugars by a resorcinol sulfuric acid micromethod","volume":"175","author":"Monsigny","year":"1988","journal-title":"Anal. Biochem."},{"key":"10.1016\/j.jconrel.2018.03.035_bb0145","doi-asserted-by":"crossref","first-page":"247","DOI":"10.1007\/978-1-62703-260-5_16","article-title":"Mannosylated and histidylated LPR technology for vaccination with tumor antigen mRNA","volume":"969","author":"Pichon","year":"2013","journal-title":"Methods Mol. Biol."},{"key":"10.1016\/j.jconrel.2018.03.035_bb0150","doi-asserted-by":"crossref","DOI":"10.1080\/2162402X.2016.1164363","article-title":"Intra-cheek immunization as a novel vaccination route for therapeutic vaccines of head and neck squamous cell carcinomas using plasmo virus-like particles","volume":"5","author":"Macedo","year":"2016","journal-title":"OncoImmunology."},{"key":"10.1016\/j.jconrel.2018.03.035_bb0155","doi-asserted-by":"crossref","first-page":"71","DOI":"10.1016\/S1074-7613(00)80160-0","article-title":"Langerin, a novel C-type lectin specific to Langerhans cells, is an endocytic receptor that induces the formation of Birbeck granules","volume":"12","author":"Valladeau","year":"2000","journal-title":"Immunity"},{"key":"10.1016\/j.jconrel.2018.03.035_bb0160","doi-asserted-by":"crossref","first-page":"1249","DOI":"10.2353\/ajpath.2007.070225","article-title":"CXCL12-CXCR4 engagement is required for migration of cutaneous dendritic cells","volume":"171","author":"Kabashima","year":"2007","journal-title":"Am. J. Pathol."},{"key":"10.1016\/j.jconrel.2018.03.035_bb0165","doi-asserted-by":"crossref","first-page":"23","DOI":"10.1016\/S0092-8674(00)80059-8","article-title":"CCR7 coordinates the primary immune response by establishing functional microenvironments in secondary lymphoid organs","volume":"99","author":"F\u00f6rster","year":"1999","journal-title":"Cell"},{"key":"10.1016\/j.jconrel.2018.03.035_bb0170","doi-asserted-by":"crossref","first-page":"617","DOI":"10.1038\/nri1418","article-title":"Matrix metalloproteinases as modulators of inflammation and innate immunity","volume":"4","author":"Parks","year":"2004","journal-title":"Nat. Rev. Immunol."},{"key":"10.1016\/j.jconrel.2018.03.035_bb0175","doi-asserted-by":"crossref","first-page":"57","DOI":"10.1016\/j.brainresrev.2008.12.020","article-title":"Role of interleukin-1beta during pain and inflammation","volume":"60","author":"Ren","year":"2009","journal-title":"Brain Res. Rev."},{"key":"10.1016\/j.jconrel.2018.03.035_bb0180","doi-asserted-by":"crossref","first-page":"986","DOI":"10.1161\/ATVBAHA.110.207449","article-title":"Prostaglandins and inflammation","volume":"31","author":"Ricciotti","year":"2011","journal-title":"Arterioscler. Thromb. Vasc. Biol."},{"key":"10.1016\/j.jconrel.2018.03.035_bb0185","doi-asserted-by":"crossref","first-page":"519","DOI":"10.1016\/j.immuni.2007.01.017","article-title":"Monocyte-derived dendritic cells formed at the infection site control the induction of protective T helper 1 responses against Leishmania","volume":"26","author":"Le\u00f3n","year":"2007","journal-title":"Immunity"},{"key":"10.1016\/j.jconrel.2018.03.035_bb0190","doi-asserted-by":"crossref","first-page":"647","DOI":"10.1084\/jem.176.3.647","article-title":"Sialoadhesin on macrophages: its identification as a lymphocyte adhesion molecule","volume":"176","author":"van den Berg","year":"1992","journal-title":"J. Exp. Med."},{"key":"10.1016\/j.jconrel.2018.03.035_bb0195","doi-asserted-by":"crossref","first-page":"394","DOI":"10.1002\/eji.1830260219","article-title":"Expression of a mannose\/fucose membrane lectin on human dendritic cells","volume":"26","author":"Avram\u00e9as","year":"1996","journal-title":"Eur. J. Immunol."},{"key":"10.1016\/j.jconrel.2018.03.035_bb0200","doi-asserted-by":"crossref","first-page":"109","DOI":"10.1590\/S1984-82502013000700009","article-title":"Glycodendritic structures: tools to interact with DC-SIGN","volume":"49","author":"Reina","year":"2013","journal-title":"Braz. J. Pharm. Sci."},{"key":"10.1016\/j.jconrel.2018.03.035_bb0205","doi-asserted-by":"crossref","first-page":"45","DOI":"10.1016\/j.jconrel.2015.06.028","article-title":"Multicomponent mannose-containing liposomes efficiently deliver RNA in murine immature dendritic cells and provide productive anti-tumour response in murine melanoma model","volume":"213","author":"Markov","year":"2015","journal-title":"J. Control. Release Off. J. Control. Release Soc."},{"key":"10.1016\/j.jconrel.2018.03.035_bb0210","doi-asserted-by":"crossref","first-page":"315","DOI":"10.3109\/1061186X.2010.504262","article-title":"Selective gene delivery in dendritic cells with mannosylated and histidylated lipopolyplexes","volume":"19","author":"Perche","year":"2011","journal-title":"J. Drug Target."},{"key":"10.1016\/j.jconrel.2018.03.035_bb0215","doi-asserted-by":"crossref","first-page":"341","DOI":"10.1039\/9781849739986-00341","article-title":"Glycolipid-based nanosystems for the delivery of drugs, genes and vaccine adjuvant applications","volume":"40","author":"Benvegnu","year":"2014","journal-title":"Carbohydr. Chem."},{"key":"10.1016\/j.jconrel.2018.03.035_bb0220","doi-asserted-by":"crossref","first-page":"2385","DOI":"10.1021\/bc8002524","article-title":"Influence of ligand valency on the targeting of immature human dendritic cells by mannosylated liposomes","volume":"19","author":"Espuelas","year":"2008","journal-title":"Bioconjug. Chem."},{"key":"10.1016\/j.jconrel.2018.03.035_bb0225","doi-asserted-by":"crossref","first-page":"171","DOI":"10.1111\/j.1432-1033.1982.tb07036.x","article-title":"The preferred conformation of oligosaccharides derived from the complex-type carbohydrate portions of glycoproteins","volume":"129","author":"Bock","year":"1982","journal-title":"Eur. J. Biochem."},{"key":"10.1016\/j.jconrel.2018.03.035_bb0230","doi-asserted-by":"crossref","first-page":"3733","DOI":"10.1039\/c2cc30773a","article-title":"Design and synthesis of a \u201cclick\u201d high-mannose oligosaccharide mimic emulating Man8 binding affinity towards Con A","volume":"48","author":"Cendret","year":"2012","journal-title":"Chem. Commun."},{"key":"10.1016\/j.jconrel.2018.03.035_bb0235","doi-asserted-by":"crossref","first-page":"1978","DOI":"10.1002\/chem.201405481","article-title":"Synthesis of high-mannose oligosaccharide analogues through click chemistry: true functional mimics of their natural counterparts against lectins?","volume":"21","author":"Fran\u00e7ois-Heude","year":"2015","journal-title":"Chemistry"},{"key":"10.1016\/j.jconrel.2018.03.035_bb0240","doi-asserted-by":"crossref","DOI":"10.1016\/j.jid.2017.04.016","article-title":"Critical role for skin-derived migratory DCs and Langerhans cells in TFH and GC responses after intradermal immunization","author":"Levin","year":"2017","journal-title":"J. Invest. Dermatol."},{"key":"10.1016\/j.jconrel.2018.03.035_bb0245","doi-asserted-by":"crossref","first-page":"615","DOI":"10.1038\/jid.2011.346","article-title":"Intradermal immunization triggers epidermal Langerhans cell mobilization required for CD8 T-cell immune responses","volume":"132","author":"Liard","year":"2012","journal-title":"J. Invest. Dermatol."},{"key":"10.1016\/j.jconrel.2018.03.035_bb0250","doi-asserted-by":"crossref","first-page":"6176","DOI":"10.1016\/j.vaccine.2010.07.025","article-title":"A liposome-based platform, VacciMax, and its modified water-free platform DepoVax enhance efficacy of in vivo nucleic acid delivery","volume":"28","author":"Karkada","year":"2010","journal-title":"Vaccine"},{"key":"10.1016\/j.jconrel.2018.03.035_bb0255","doi-asserted-by":"crossref","first-page":"14604","DOI":"10.1073\/pnas.1209367109","article-title":"Nonviral delivery of self-amplifying RNA vaccines","volume":"109","author":"Geall","year":"2012","journal-title":"Proc. Natl. Acad. Sci. U. S. A."},{"key":"10.1016\/j.jconrel.2018.03.035_bb0260","doi-asserted-by":"crossref","first-page":"176","DOI":"10.1016\/j.cell.2017.03.016","article-title":"Modified mRNA vaccines protect against Zika virus infection","volume":"169","author":"Richner","year":"2017","journal-title":"Cell"},{"key":"10.1016\/j.jconrel.2018.03.035_bb0265","doi-asserted-by":"crossref","first-page":"248","DOI":"10.1038\/nature21428","article-title":"Zika virus protection by a single low-dose nucleoside-modified mRNA vaccination","volume":"543","author":"Pardi","year":"2017","journal-title":"Nature"},{"key":"10.1016\/j.jconrel.2018.03.035_bb0270","doi-asserted-by":"crossref","DOI":"10.1186\/s40425-015-0068-y","article-title":"Self-adjuvanted mRNA vaccination in advanced prostate cancer patients: a first-in-man phase I\/IIa study","volume":"3","author":"K\u00fcbler","year":"2015","journal-title":"J. Immunother. Cancer."},{"key":"10.1016\/j.jconrel.2018.03.035_bb0275","doi-asserted-by":"crossref","first-page":"1124","DOI":"10.1002\/eji.200535443","article-title":"The Shiga toxin B-subunit targets antigen in vivo to dendritic cells and elicits anti-tumor immunity","volume":"36","author":"Vingert","year":"2006","journal-title":"Eur. J. Immunol."},{"key":"10.1016\/j.jconrel.2018.03.035_bb0280","doi-asserted-by":"crossref","DOI":"10.3389\/fimmu.2012.00013","article-title":"Targeting dendritic cells in vivo for Cancer therapy","volume":"3","author":"Caminschi","year":"2012","journal-title":"Front. Immunol."},{"key":"10.1016\/j.jconrel.2018.03.035_bb0285","doi-asserted-by":"crossref","first-page":"719","DOI":"10.1038\/cmi.2014.100","article-title":"Toll-like receptor agonists shape the immune responses to a mannose receptor-targeted cancer vaccine","volume":"12","author":"He","year":"2015","journal-title":"Cell. Mol. Immunol."},{"key":"10.1016\/j.jconrel.2018.03.035_bb0290","doi-asserted-by":"crossref","first-page":"4574","DOI":"10.1016\/j.biomaterials.2011.03.015","article-title":"Antitumor activity of liposomal ErbB2\/HER2 epitope peptide-based vaccine constructs incorporating TLR agonists and mannose receptor targeting","volume":"32","author":"Thomann","year":"2011","journal-title":"Biomaterials"},{"key":"10.1016\/j.jconrel.2018.03.035_bb0295","first-page":"159","article-title":"Gene delivery by lipoplexes and polyplexes","volume":"40","author":"Tros de Ilarduya","year":"2010","journal-title":"Eur. J. Pharm. Sci. Off. J. Eur. Fed. Pharm. Sci."},{"key":"10.1016\/j.jconrel.2018.03.035_bb0300","doi-asserted-by":"crossref","first-page":"465","DOI":"10.1038\/nm.3105","article-title":"Persistent antigen at vaccination sites induces tumor-specific CD8+ T cell sequestration, dysfunction and deletion","volume":"19","author":"Hailemichael","year":"2013","journal-title":"Nat. Med."}],"container-title":["Journal of Controlled Release"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0168365918301743?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0168365918301743?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2023,9,1]],"date-time":"2023-09-01T23:49:28Z","timestamp":1693612168000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0168365918301743"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2018,5]]},"references-count":60,"alternative-id":["S0168365918301743"],"URL":"https:\/\/doi.org\/10.1016\/j.jconrel.2018.03.035","relation":{},"ISSN":["0168-3659"],"issn-type":[{"value":"0168-3659","type":"print"}],"subject":[],"published":{"date-parts":[[2018,5]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Preclinical evaluation of mRNA trimannosylated lipopolyplexes as therapeutic cancer vaccines targeting dendritic cells","name":"articletitle","label":"Article Title"},{"value":"Journal of Controlled Release","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.jconrel.2018.03.035","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2018 Elsevier B.V. All rights reserved.","name":"copyright","label":"Copyright"}]}}