{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,24]],"date-time":"2026-09-24T15:10:00Z","timestamp":1790262600424,"version":"4.1.0"},"reference-count":46,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2021,4,1]],"date-time":"2021-04-01T00:00:00Z","timestamp":1617235200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2021,4,1]],"date-time":"2021-04-01T00:00:00Z","timestamp":1617235200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2021,4,1]],"date-time":"2021-04-01T00:00:00Z","timestamp":1617235200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2021,4,1]],"date-time":"2021-04-01T00:00:00Z","timestamp":1617235200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2021,4,1]],"date-time":"2021-04-01T00:00:00Z","timestamp":1617235200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2021,4,1]],"date-time":"2021-04-01T00:00:00Z","timestamp":1617235200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2021,4,1]],"date-time":"2021-04-01T00:00:00Z","timestamp":1617235200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"funder":[{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["81620108017"],"award-info":[{"award-number":["81620108017"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["81771879"],"award-info":[{"award-number":["81771879"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["81871462"],"award-info":[{"award-number":["81871462"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100003785","name":"Guangdong Medical Research Foundation","doi-asserted-by":"publisher","award":["20161027E030069"],"award-info":[{"award-number":["20161027E030069"]}],"id":[{"id":"10.13039\/501100003785","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100003785","name":"Guangdong Medical Research Foundation","doi-asserted-by":"publisher","award":["A2018254"],"award-info":[{"award-number":["A2018254"]}],"id":[{"id":"10.13039\/501100003785","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100012166","name":"National Key Research and Development Program of China","doi-asserted-by":"publisher","award":["2018YFC0910600"],"award-info":[{"award-number":["2018YFC0910600"]}],"id":[{"id":"10.13039\/501100012166","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Journal of Controlled Release"],"published-print":{"date-parts":[[2021,4]]},"DOI":"10.1016\/j.jconrel.2021.02.019","type":"journal-article","created":{"date-parts":[[2021,2,23]],"date-time":"2021-02-23T23:04:30Z","timestamp":1614121470000},"page":"171-183","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":26,"special_numbering":"C","title":["Near-infrared fluorescence-guided resection of micrometastases derived from esophageal squamous cell carcinoma using a c-Met-targeted probe in a preclinical xenograft model"],"prefix":"10.1016","volume":"332","author":[{"given":"Mingzhu","family":"Liang","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Meilin","family":"Yang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fen","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xiaojin","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bailiang","family":"He","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chaoming","family":"Mei","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jianzhong","family":"He","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yujing","family":"Lin","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Qingdong","family":"Cao","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dan","family":"Li","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hong","family":"Shan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.jconrel.2021.02.019_bb0005","first-page":"394","article-title":"Global cancer statistics 2018: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries","volume":"68","author":"Bray","year":"2018","journal-title":"CA Cancer J. Clin."},{"key":"10.1016\/j.jconrel.2021.02.019_bb0010","doi-asserted-by":"crossref","first-page":"381","DOI":"10.1136\/gutjnl-2014-308124","article-title":"Global incidence of oesophageal cancer by histological subtype in 2012","volume":"64","author":"Arnold","year":"2015","journal-title":"Gut."},{"key":"10.1016\/j.jconrel.2021.02.019_bb0015","unstructured":"NCCN guideline for Esophageal and Esophagogastric Junction Cancers, https:\/\/www.nccn.org\/professionals\/physician_gls\/default.aspx#esophageal. (accessed on 28.10.20)."},{"key":"10.1016\/j.jconrel.2021.02.019_bb0020","doi-asserted-by":"crossref","first-page":"360","DOI":"10.1097\/00000658-200109000-00010","article-title":"Histologic tumor type is an independent prognostic parameter in esophageal cancer: lessons from more than 1,000 consecutive resections at a single center in the Western world","volume":"234","author":"Siewert","year":"2001","journal-title":"Ann. Surg."},{"key":"10.1016\/j.jconrel.2021.02.019_bb0025","doi-asserted-by":"crossref","first-page":"1074","DOI":"10.1016\/j.athoracsur.2016.03.117","article-title":"Risk factors for local recurrence and optimal length of esophagectomy in esophageal squamous cell carcinoma","volume":"102","author":"Kang","year":"2016","journal-title":"Ann. Thorac. Surg."},{"key":"10.1016\/j.jconrel.2021.02.019_bb0030","doi-asserted-by":"crossref","first-page":"S731","DOI":"10.21037\/jtd.2017.03.171","article-title":"Three-field LN dissection in esophageal cancer surgery","volume":"9","author":"Matsuda","year":"2017","journal-title":"J. Thorac. Dis."},{"key":"10.1016\/j.jconrel.2021.02.019_bb0035","doi-asserted-by":"crossref","first-page":"2087","DOI":"10.1245\/s10434-015-5086-y","article-title":"Solitary lymph node recurrence of esophageal squamous cell carcinoma: surgical failure or systemic disease?","volume":"23","author":"Makino","year":"2016","journal-title":"Ann. Surg. Oncol."},{"key":"10.1016\/j.jconrel.2021.02.019_bb0040","doi-asserted-by":"crossref","first-page":"205","DOI":"10.1016\/j.jamcollsurg.2003.10.005","article-title":"Recurrence pattern of squamous cell carcinoma of the thoracic esophagus after extended radical esophagectomy with three-field lymphadenectomy","volume":"198","author":"Nakagawa","year":"2004","journal-title":"J. Am. Coll. Surg."},{"key":"10.1016\/j.jconrel.2021.02.019_bb0045","doi-asserted-by":"crossref","first-page":"764","DOI":"10.1148\/radiol.2281020423","article-title":"Metastasis to regional LNs in patients with esophageal squamous cell carcinoma: CT versus FDG PET for presurgical detection prospective study","volume":"227","author":"Yoon","year":"2003","journal-title":"Radiology"},{"key":"10.1016\/j.jconrel.2021.02.019_bb0050","doi-asserted-by":"crossref","first-page":"1380","DOI":"10.1007\/s00464-009-0783-x","article-title":"Comparison of endoscopic ultrasonography (EUS), positron emission tomography (PET), and computed tomography (CT) in the preoperative locoregional staging of resectable esophageal cancer","volume":"24","author":"Choi","year":"2010","journal-title":"Surg. Endosc."},{"key":"10.1016\/j.jconrel.2021.02.019_bb0055","doi-asserted-by":"crossref","first-page":"2146","DOI":"10.21037\/jtd.2016.07.71","article-title":"Accuracy of ultrasound for the diagnosis of cervical lymph node metastasis in esophageal cancer: a systematic review and meta-analysis","volume":"8","author":"Leng","year":"2016","journal-title":"J. Thorac. Dis."},{"key":"10.1016\/j.jconrel.2021.02.019_bb0060","doi-asserted-by":"crossref","first-page":"1168","DOI":"10.1126\/science.1125949","article-title":"Molecular imaging in cancer","volume":"312","author":"Weissleder","year":"2006","journal-title":"Science"},{"key":"10.1016\/j.jconrel.2021.02.019_bb0065","doi-asserted-by":"crossref","first-page":"22431","DOI":"10.1002\/anie.202010089","article-title":"Engineering the protein Corona structure on gold NanoclustersEnables red-shifted emissions in the second near-infrared Windowfor gastrointestinal imaging","volume":"59","author":"Wang","year":"2020","journal-title":"Angew. Chem. Int. Ed. Engl."},{"key":"10.1016\/j.jconrel.2021.02.019_bb0070","doi-asserted-by":"crossref","first-page":"2730","DOI":"10.1158\/1078-0432.CCR-16-0437","article-title":"Tumor-specific uptake of fluorescent bevacizumab-IRDye800CW microdosing in patients with primary breast cancer: a phase I feasibility study","volume":"23","author":"Lamberts","year":"2017","journal-title":"Clin. Cancer Res."},{"key":"10.1016\/j.jconrel.2021.02.019_bb0075","doi-asserted-by":"crossref","first-page":"3658","DOI":"10.1158\/1078-0432.CCR-14-3284","article-title":"Safety and tumor specificity of Cetuximab-IRDye800 for surgical navigation in head and neck Cancer","volume":"21","author":"Rosenthal","year":"2015","journal-title":"Clin. Cancer Res."},{"key":"10.1016\/j.jconrel.2021.02.019_bb0080","doi-asserted-by":"crossref","first-page":"4744","DOI":"10.1158\/1078-0432.CCR-16-2968","article-title":"Sensitivity and specificity of cetuximab-IRDye800CW to identify regional metastatic disease in head and neck Cancer","volume":"23","author":"Rosenthal","year":"2017","journal-title":"Clin. Cancer Res."},{"key":"10.1016\/j.jconrel.2021.02.019_bb0085","doi-asserted-by":"crossref","first-page":"7","DOI":"10.1136\/gutjnl-2017-314953","article-title":"Near-infrared fluorescence molecular endoscopy detects dysplastic oesophageal lesions using topical and systemic tracer of vascular endothelial growth factor A","volume":"68","author":"Nagengast","year":"2019","journal-title":"Gut."},{"key":"10.1016\/j.jconrel.2021.02.019_bb0090","doi-asserted-by":"crossref","first-page":"546","DOI":"10.1016\/j.jtcvs.2016.04.025","article-title":"Safety and feasibility of near-infrared image-guided lymphaticmapping of regional lymph nodes in esophageal cancer","volume":"152","author":"Hachey","year":"2016","journal-title":"J. Thorac. Cardiovasc. Surg."},{"key":"10.1016\/j.jconrel.2021.02.019_bb0095","doi-asserted-by":"crossref","first-page":"1613","DOI":"10.1016\/j.athoracsur.2018.01.083","article-title":"Near-infrared lymphatic mapping of the recurrent laryngeal nerve nodes in T1 esophageal cancer","volume":"105","author":"Park","year":"2018","journal-title":"Ann. Thorac. Surg."},{"key":"10.1016\/j.jconrel.2021.02.019_bb0100","doi-asserted-by":"crossref","first-page":"169","DOI":"10.1038\/nature20805","article-title":"Analysis Working Group. Integrated genomic characterization of oesophageal carcinoma","volume":"541","author":"Cancer Genome Atlas Research Network, Analysis Working Group: Asan University","year":"2017","journal-title":"Nature"},{"key":"10.1016\/j.jconrel.2021.02.019_bb0105","doi-asserted-by":"crossref","first-page":"294","DOI":"10.1053\/j.gastro.2012.10.030","article-title":"Optical imaging of periostin enables early endoscopic detection and characterization of esophageal cancer in mice","volume":"144","author":"Wong","year":"2013","journal-title":"Gastroenterology"},{"key":"10.1016\/j.jconrel.2021.02.019_bb0110","doi-asserted-by":"crossref","first-page":"915","DOI":"10.1038\/nrm1261","article-title":"Met, metastasis, motility and more","volume":"4","author":"Birchmeier","year":"2003","journal-title":"Nat. Rev. Mol. Cell Biol."},{"key":"10.1016\/j.jconrel.2021.02.019_bb0115","doi-asserted-by":"crossref","first-page":"955","DOI":"10.1038\/nm.3641","article-title":"Detection of colorectal polyps in humans using an intravenously administered fluorescent peptide targeted against c-Met","volume":"21","author":"Burggraaf","year":"2015","journal-title":"Nat. Med."},{"key":"10.1016\/j.jconrel.2021.02.019_bb0120","doi-asserted-by":"crossref","first-page":"562","DOI":"10.1038\/nrclinonc.2017.40","article-title":"Van Schaeybroeck S; MErCuRIC consortium, targeting c-MET in gastrointestinal tumours: rationale, opportunities and challenges","volume":"14","author":"Bradley","year":"2017","journal-title":"Nat. Rev. Clin. Oncol."},{"key":"10.1016\/j.jconrel.2021.02.019_bb0125","doi-asserted-by":"crossref","first-page":"6","DOI":"10.1186\/s12885-014-1001-3","article-title":"Expression and clinical significance of c-Met in advanced esophageal squamous cell carcinoma","volume":"15","author":"Xu","year":"2015","journal-title":"BMC Cancer"},{"key":"10.1016\/j.jconrel.2021.02.019_bb0130","doi-asserted-by":"crossref","first-page":"587","DOI":"10.7150\/jca.13687","article-title":"C-met as a molecular marker for esophageal squamous cell carcinoma and its association with clinical outcome","volume":"7","author":"Xu","year":"2016","journal-title":"J. Cancer"},{"key":"10.1016\/j.jconrel.2021.02.019_bb0135","doi-asserted-by":"crossref","first-page":"899","DOI":"10.1245\/s10434-018-07126-5","article-title":"Effect of c-met and CD44v6 expression in resistance to chemotherapy in esophageal squamous cell carcinoma","volume":"26","author":"Hara","year":"2019","journal-title":"Ann. Surg. Oncol."},{"key":"10.1016\/j.jconrel.2021.02.019_bb0140","doi-asserted-by":"crossref","first-page":"971","DOI":"10.1038\/s41401-018-0198-0","article-title":"SHR-A1403, a novel c-Met antibody-drug conjugate, exerts encouraging anti-tumor activity in c-Met-overexpressing models","volume":"40","author":"Yang","year":"2019","journal-title":"Acta Pharmacol. Sin."},{"key":"10.1016\/j.jconrel.2021.02.019_bb0145","doi-asserted-by":"crossref","first-page":"1097","DOI":"10.1080\/00498254.2018.1534030","article-title":"Preclinical pharmacokinetics of a novel anti-c-Met antibody-drug conjugate, SHR-A1403, in rodents and non-human primates","volume":"49","author":"Yang","year":"2019","journal-title":"Xenobiotica"},{"key":"10.1016\/j.jconrel.2021.02.019_bb0150","doi-asserted-by":"crossref","first-page":"329","DOI":"10.1021\/mp300461b","article-title":"Targeting the EphB4 receptor for cancer diagnosis and therapy monitoring","volume":"10","author":"Li","year":"2013","journal-title":"Mol. Pharm."},{"key":"10.1016\/j.jconrel.2021.02.019_bb0155","doi-asserted-by":"crossref","first-page":"910715","DOI":"10.1155\/2015\/910715","article-title":"A versatile orthotopic nude mouse model for study of esophageal squamous cell carcinoma","volume":"2015","author":"Ip","year":"2015","journal-title":"Biomed. Res. Int."},{"key":"10.1016\/j.jconrel.2021.02.019_bb0160","doi-asserted-by":"crossref","first-page":"1592","DOI":"10.2967\/jnumed.111.102293","article-title":"Immuno-PET of the hepatocyte growth factor receptor Met using the 1-armed antibody onartuzumab","volume":"53","author":"Jagoda","year":"2012","journal-title":"J. Nucl. Med."},{"key":"10.1016\/j.jconrel.2021.02.019_bb0165","doi-asserted-by":"crossref","first-page":"41","DOI":"10.1186\/s13550-017-0286-z","article-title":"Analysis of progress and challenges for various patterns of c-MET-targeted molecular imaging: a systematic review","volume":"7","author":"Han","year":"2017","journal-title":"EJNMMI Res."},{"key":"10.1016\/j.jconrel.2021.02.019_bb0170","doi-asserted-by":"crossref","first-page":"271","DOI":"10.1016\/S0168-3659(99)00248-5","article-title":"Tumor vascular permeability and the EPR effect in macromolecular therapeutics: a review","volume":"65","author":"Maeda","year":"2000","journal-title":"J. Control. Release"},{"key":"10.1016\/j.jconrel.2021.02.019_bb0175","doi-asserted-by":"crossref","first-page":"1116","DOI":"10.2967\/jnumed.109.061820","article-title":"PET of EGFR antibody distribution in head and neck squamous cell carcinoma models","volume":"50","author":"Niu","year":"2009","journal-title":"J. Nucl. Med."},{"key":"10.1016\/j.jconrel.2021.02.019_bb0180","doi-asserted-by":"crossref","first-page":"2095","DOI":"10.1158\/1078-0432.CCR-09-2495","article-title":"Cetuximab-based immunotherapy and radioimmunotherapy of head and neck squamous cell carcinoma","volume":"16","author":"Niu","year":"2010","journal-title":"Clin. Cancer Res."},{"key":"10.1016\/j.jconrel.2021.02.019_bb0185","first-page":"814s","article-title":"Physiological barriers to delivery of monoclonal antibodies and other macromolecules in tumors","volume":"50","author":"Jain","year":"1990","journal-title":"Cancer Res."},{"key":"10.1016\/j.jconrel.2021.02.019_bb0190","doi-asserted-by":"crossref","first-page":"722","DOI":"10.1007\/s11307-013-0652-9","article-title":"Preclinical comparison of near-infrared-labeled cetuximab and panitumumab for optical imaging of head and neck squamous cell carcinoma","volume":"15","author":"Day","year":"2013","journal-title":"Mol. Imaging Biol."},{"key":"10.1016\/j.jconrel.2021.02.019_bb0195","doi-asserted-by":"crossref","first-page":"2","DOI":"10.1002\/jso.23946","article-title":"A ratiometric threshold for determining presence of cancer during fluorescence-guided surgery","volume":"112","author":"Warram","year":"2015","journal-title":"J. Surg. Oncol."},{"key":"10.1016\/j.jconrel.2021.02.019_bb0200","doi-asserted-by":"crossref","first-page":"153","DOI":"10.1016\/j.suronc.2017.03.002","article-title":"SGM-101: an innovative near-infrared dye-antibody conjugate that targets CEA for fluorescence-guided surgery","volume":"26","author":"Gutowski","year":"2017","journal-title":"Surg. Oncol."},{"key":"10.1016\/j.jconrel.2021.02.019_bb0205","doi-asserted-by":"crossref","first-page":"61","DOI":"10.1177\/153303460800700108","article-title":"Assessment of bevacizumab conjugated to Cy5.5 for detection of head and neck cancer xenografts","volume":"7","author":"Withrow","year":"2008","journal-title":"Technol. Cancer Res. Treat."},{"key":"10.1016\/j.jconrel.2021.02.019_bb0210","doi-asserted-by":"crossref","first-page":"119","DOI":"10.1016\/j.jss.2013.11.1089","article-title":"Use of monoclonal antibody-IRDye800CW bioconjugates in the resection of breast cancer","volume":"188","author":"Korb","year":"2014","journal-title":"J. Surg. Res."},{"key":"10.1016\/j.jconrel.2021.02.019_bb0215","doi-asserted-by":"crossref","first-page":"4465","DOI":"10.1073\/pnas.1718917115","article-title":"Shortwave infrared fluorescence imaging with the clinically approved near-infrared dye indocyanine green","volume":"115","author":"Carr","year":"2018","journal-title":"Proc. Natl. Acad. Sci. U. S. A."},{"key":"10.1016\/j.jconrel.2021.02.019_bb0220","doi-asserted-by":"crossref","first-page":"0057","DOI":"10.1038\/s41551-017-0057","article-title":"Successively activatable ultrasensitive probe for imaging tumour acidity and hypoxia","volume":"1","author":"Zheng","year":"2017","journal-title":"Nat. Biomed. Eng."},{"key":"10.1016\/j.jconrel.2021.02.019_bb0225","doi-asserted-by":"crossref","first-page":"3429","DOI":"10.1021\/acsabm.9b00381","article-title":"Electrostatically assembled multilayered films of biopolymer","volume":"2","author":"Xu","year":"2019","journal-title":"ACS Appl. Bio Mater."},{"key":"10.1016\/j.jconrel.2021.02.019_bb0230","doi-asserted-by":"crossref","first-page":"741","DOI":"10.1021\/acsapm.9b01051","article-title":"Temperature-responsive multilayer films of micelle-based composites for controlled release of a third-generation EGFR inhibitor","volume":"2","author":"Xu","year":"2020","journal-title":"ACS Appl. Polym. Mater."}],"container-title":["Journal of Controlled Release"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0168365921000845?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0168365921000845?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,9,29]],"date-time":"2025-09-29T15:55:49Z","timestamp":1759161349000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0168365921000845"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,4]]},"references-count":46,"alternative-id":["S0168365921000845"],"URL":"https:\/\/doi.org\/10.1016\/j.jconrel.2021.02.019","relation":{},"ISSN":["0168-3659"],"issn-type":[{"value":"0168-3659","type":"print"}],"subject":[],"published":{"date-parts":[[2021,4]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Near-infrared fluorescence-guided resection of micrometastases derived from esophageal squamous cell carcinoma using a c-Met-targeted probe in a preclinical xenograft model","name":"articletitle","label":"Article Title"},{"value":"Journal of Controlled Release","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.jconrel.2021.02.019","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2021 Elsevier B.V. All rights reserved.","name":"copyright","label":"Copyright"}]}}