{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,27]],"date-time":"2026-10-27T19:50:30Z","timestamp":1793130630875,"version":"4.5.0"},"reference-count":220,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2021,10,1]],"date-time":"2021-10-01T00:00:00Z","timestamp":1633046400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2021,10,1]],"date-time":"2021-10-01T00:00:00Z","timestamp":1633046400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2021,10,1]],"date-time":"2021-10-01T00:00:00Z","timestamp":1633046400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2021,10,1]],"date-time":"2021-10-01T00:00:00Z","timestamp":1633046400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2021,10,1]],"date-time":"2021-10-01T00:00:00Z","timestamp":1633046400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2021,10,1]],"date-time":"2021-10-01T00:00:00Z","timestamp":1633046400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2021,10,1]],"date-time":"2021-10-01T00:00:00Z","timestamp":1633046400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Journal of Controlled Release"],"published-print":{"date-parts":[[2021,10]]},"DOI":"10.1016\/j.jconrel.2021.08.033","type":"journal-article","created":{"date-parts":[[2021,8,20]],"date-time":"2021-08-20T23:21:05Z","timestamp":1629501665000},"page":"164-189","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":143,"special_numbering":"C","title":["Nanoceria, the versatile nanoparticles: Promising biomedical applications"],"prefix":"10.1016","volume":"338","author":[{"given":"Mohd Aslam","family":"Saifi","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sudipta","family":"Seal","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chandraiah","family":"Godugu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.jconrel.2021.08.033_bb0005","doi-asserted-by":"crossref","first-page":"213","DOI":"10.3109\/10408444.2010.529105","article-title":"Exposure, health and ecological effects review of engineered nanoscale cerium and cerium oxide associated with its use as a fuel additive","volume":"41","author":"Cassee","year":"2011","journal-title":"Crit Rev Toxicol."},{"key":"10.1016\/j.jconrel.2021.08.033_bb0010","doi-asserted-by":"crossref","first-page":"165","DOI":"10.1016\/0167-2738(92)90102-U","article-title":"Electrical properties of ceria-based oxides and their application to solid oxide fuel cells","volume":"52","author":"Eguchi","year":"1992","journal-title":"Solid State Ionics"},{"key":"10.1016\/j.jconrel.2021.08.033_bb0015","doi-asserted-by":"crossref","first-page":"33","DOI":"10.1016\/j.bios.2017.04.037","article-title":"Bio-sensing applications of cerium oxide nanoparticles: Advantages and disadvantages","volume":"96","author":"Charbgoo","year":"2017","journal-title":"Biosens Bioelectron."},{"key":"10.1016\/j.jconrel.2021.08.033_bb0020","doi-asserted-by":"crossref","first-page":"439","DOI":"10.4028\/www.scientific.net\/MSF.315-317.439","article-title":"Ultraviolet absorption spectra of CeO2 nano-particles","author":"Tsunekawa","year":"1999","journal-title":"Mater Sci Forum. Trans Tech Publ"},{"key":"10.1016\/j.jconrel.2021.08.033_bb0025","doi-asserted-by":"crossref","first-page":"390","DOI":"10.1039\/C4EN00079J","article-title":"Exploring the properties and applications of nanoceria: is there still plenty of room at the bottom?","volume":"1","author":"Reed","year":"2014","journal-title":"Environ Sci Nano"},{"key":"10.1016\/j.jconrel.2021.08.033_bb0030","doi-asserted-by":"crossref","first-page":"84","DOI":"10.1186\/s12951-019-0516-9","article-title":"Synthesis and biomedical applications of nanoceria, a redox active nanoparticle","volume":"17","author":"Thakur","year":"2019","journal-title":"J Nanobiotechnology"},{"key":"10.1016\/j.jconrel.2021.08.033_bb0035","doi-asserted-by":"crossref","first-page":"97","DOI":"10.3390\/antiox7080097","article-title":"Cerium oxide nanoparticles: a brief review of their synthesis methods and biomedical applications","volume":"7","author":"Dhall","year":"2018","journal-title":"Antioxidants"},{"key":"10.1016\/j.jconrel.2021.08.033_bb0040","doi-asserted-by":"crossref","first-page":"1918","DOI":"10.1016\/j.biomaterials.2006.11.036","article-title":"Auto-catalytic ceria nanoparticles offer neuroprotection to adult rat spinal cord neurons","volume":"28","author":"Das","year":"2007","journal-title":"Biomaterials."},{"key":"10.1016\/j.jconrel.2021.08.033_bb0045","doi-asserted-by":"crossref","first-page":"752","DOI":"10.1126\/science.1111568","article-title":"Electron localization determines defect formation on ceria substrates","volume":"309","author":"Esch","year":"2005","journal-title":"Science"},{"key":"10.1016\/j.jconrel.2021.08.033_bb0050","doi-asserted-by":"crossref","first-page":"133113","DOI":"10.1063\/1.2061873","article-title":"Size dependency variation in lattice parameter and valency states in nanocrystalline cerium oxide","volume":"87","author":"Deshpande","year":"2005","journal-title":"Appl. Phys. Lett."},{"key":"10.1016\/j.jconrel.2021.08.033_bb0055","doi-asserted-by":"crossref","first-page":"5144","DOI":"10.1021\/cm061580n","article-title":"Concentration of Ce3+ and oxygen vacancies in cerium oxide nanoparticles","volume":"18","author":"Dutta","year":"2006","journal-title":"Chem. Mater."},{"key":"10.1016\/j.jconrel.2021.08.033_bb0060","doi-asserted-by":"crossref","first-page":"10726","DOI":"10.1021\/nn403542p","article-title":"Absence of Ce3+ sites in chemically active colloidal ceria nanoparticles","volume":"7","author":"Cafun","year":"2013","journal-title":"ACS Nano"},{"key":"10.1016\/j.jconrel.2021.08.033_bb0065","doi-asserted-by":"crossref","first-page":"4537","DOI":"10.1021\/nn200126a","article-title":"Ce3+ ions determine redox-dependent anti-apoptotic effect of cerium oxide nanoparticles","volume":"5","author":"Celardo","year":"2011","journal-title":"ACS Nano."},{"key":"10.1016\/j.jconrel.2021.08.033_bb0070","doi-asserted-by":"crossref","first-page":"13289","DOI":"10.1039\/C9NR03473K","article-title":"Simultaneous enzyme mimicking and chemical reduction mechanisms for nanoceria as a bio-antioxidant: a catalytic model bridging computations and experiments for nanozymes","volume":"11","author":"Wang","year":"2019","journal-title":"Nanoscale. R"},{"key":"10.1016\/j.jconrel.2021.08.033_bb0075","doi-asserted-by":"crossref","first-page":"7915","DOI":"10.1016\/j.biomaterials.2012.07.024","article-title":"Cellular uptake and reactive oxygen species modulation of cerium oxide nanoparticles in human monocyte cell line U937","volume":"33","author":"Lord","year":"2012","journal-title":"Biomaterials"},{"key":"10.1016\/j.jconrel.2021.08.033_bb0080","doi-asserted-by":"crossref","first-page":"127","DOI":"10.1016\/j.actbio.2016.12.010","article-title":"Endocytosis of cerium oxide nanoparticles and modulation of reactive oxygen species in human ovarian and colon cancer cells","volume":"50","author":"Vassie","year":"2017","journal-title":"Acta Biomater."},{"key":"10.1016\/j.jconrel.2021.08.033_bb0085","doi-asserted-by":"crossref","first-page":"9693","DOI":"10.1021\/nn4026806","article-title":"Antioxidant properties of cerium oxide nanocrystals as a function of nanocrystal diameter and surface coating","volume":"7","author":"Lee","year":"2013","journal-title":"ACS Nano"},{"key":"10.1016\/j.jconrel.2021.08.033_bb0090","doi-asserted-by":"crossref","first-page":"4600","DOI":"10.1016\/j.biomaterials.2007.07.029","article-title":"Protein adsorption and cellular uptake of cerium oxide nanoparticles as a function of zeta potential","volume":"28","author":"Patil","year":"2007","journal-title":"Biomaterials."},{"key":"10.1016\/j.jconrel.2021.08.033_bb0095","doi-asserted-by":"crossref","first-page":"5321","DOI":"10.1021\/nn100816s","article-title":"Surface-charge-dependent cell localization and cytotoxicity of cerium oxide nanoparticles","volume":"4","author":"Asati","year":"2010","journal-title":"ACS Nano"},{"key":"10.1016\/j.jconrel.2021.08.033_bb0100","doi-asserted-by":"crossref","first-page":"35344","DOI":"10.1038\/srep35344","article-title":"Redox enzyme-mimicking activities of CeO 2 nanostructures: Intrinsic influence of exposed facets","volume":"6","author":"Yang","year":"2016","journal-title":"Sci. Rep."},{"key":"10.1016\/j.jconrel.2021.08.033_bb0105","doi-asserted-by":"crossref","first-page":"1700176","DOI":"10.1002\/adhm.201700176","article-title":"Europium-doped cerium oxide nanoparticles limit reactive oxygen species formation and ameliorate intestinal ischemia\u2013reperfusion injury","volume":"6","author":"Gubernatorova","year":"2017","journal-title":"Adv Healthc Mater"},{"key":"10.1016\/j.jconrel.2021.08.033_bb0110","doi-asserted-by":"crossref","first-page":"33","DOI":"10.1007\/s11837-008-0029-8","article-title":"Nanoceria as antioxidant: synthesis and biomedical applications","volume":"60","author":"Karakoti","year":"2008","journal-title":"Jom."},{"key":"10.1016\/j.jconrel.2021.08.033_bb0115","doi-asserted-by":"crossref","first-page":"4896","DOI":"10.1039\/c2cc30485f","article-title":"Cerium oxide nanoparticles scavenge nitric oxide radical ( NO)","volume":"48","author":"Dowding","year":"2012","journal-title":"Chem. Commun."},{"key":"10.1016\/j.jconrel.2021.08.033_bb0120","doi-asserted-by":"crossref","first-page":"4433","DOI":"10.1021\/jp109819u","article-title":"Direct evidence for hydroxyl radical scavenging activity of cerium oxide nanoparticles","volume":"115","author":"Xue","year":"2011","journal-title":"J. Phys. Chem. C"},{"key":"10.1016\/j.jconrel.2021.08.033_bb0125","doi-asserted-by":"crossref","first-page":"62911","DOI":"10.1039\/C6RA11131A","article-title":"Hypochlorite scavenging activity of cerium oxide nanoparticles","volume":"6","author":"Pulido-Reyes","year":"2016","journal-title":"RSC Adv."},{"key":"10.1016\/j.jconrel.2021.08.033_bb0130","doi-asserted-by":"crossref","first-page":"2848","DOI":"10.1002\/smll.200901048","article-title":"Anti-inflammatory properties of cerium oxide nanoparticles","volume":"5","author":"Hirst","year":"2009","journal-title":"Small."},{"key":"10.1016\/j.jconrel.2021.08.033_bb0135","doi-asserted-by":"crossref","first-page":"14144","DOI":"10.1021\/ja9051087","article-title":"PEGylated nanoceria as radical scavenger with tunable redox chemistry","volume":"131","author":"Karakoti","year":"2009","journal-title":"J. Am. Chem. Soc."},{"key":"10.1016\/j.jconrel.2021.08.033_bb0140","doi-asserted-by":"crossref","first-page":"6833","DOI":"10.1039\/c3ra22251a","article-title":"Synthesis of water-soluble chitosan-coated nanoceria with excellent antioxidant properties","volume":"3","author":"Zhai","year":"2013","journal-title":"RSC Adv."},{"key":"10.1016\/j.jconrel.2021.08.033_bb0145","doi-asserted-by":"crossref","first-page":"357","DOI":"10.1007\/s13346-017-0396-1","article-title":"Synthesis, physico-chemical characterization, and antioxidant effect of PEGylated cerium oxide nanoparticles","volume":"8","author":"Xue","year":"2018","journal-title":"Drug Deliv Transl Res"},{"key":"10.1016\/j.jconrel.2021.08.033_bb0150","doi-asserted-by":"crossref","first-page":"552","DOI":"10.1002\/smll.200700824","article-title":"Synthesis of biocompatible dextran-coated nanoceria with pH-dependent antioxidant properties","volume":"4","author":"Perez","year":"2008","journal-title":"Small"},{"key":"10.1016\/j.jconrel.2021.08.033_bb0155","doi-asserted-by":"crossref","first-page":"375","DOI":"10.1016\/j.colsurfb.2016.06.035","article-title":"Biomimetic nanomaterials: Development of protein coated nanoceria as a potential antioxidative nano-agent for the effective scavenging of reactive oxygen species in vitro and in zebrafish model","volume":"146","author":"Bhushan","year":"2016","journal-title":"Colloids Surf. B: Biointerfaces"},{"key":"10.1016\/j.jconrel.2021.08.033_bb0160","doi-asserted-by":"crossref","first-page":"18","DOI":"10.3390\/bioengineering4010018","article-title":"Antioxidant activity of SOD and catalase conjugated with nanocrystalline ceria","volume":"4","author":"Gil","year":"2017","journal-title":"Bioengineering"},{"key":"10.1016\/j.jconrel.2021.08.033_bb0165","doi-asserted-by":"crossref","first-page":"23580","DOI":"10.1021\/acsami.6b08219","article-title":"Insight into several factors that affect the conversion between antioxidant and oxidant activities of nanoceria","volume":"8","author":"Lu","year":"2016","journal-title":"ACS Appl. Mater. Interfaces"},{"key":"10.1016\/j.jconrel.2021.08.033_bb0170","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.redox.2014.11.007","article-title":"Redox-active cerium oxide nanoparticles protect human dermal fibroblasts from PQ-induced damage","volume":"4","author":"von Montfort","year":"2015","journal-title":"Redox Biol."},{"issue":"4","key":"10.1016\/j.jconrel.2021.08.033_bb0175","first-page":"399","article-title":"Radical nanomedicine","volume":"1","author":"Rzigalinski","year":"2006","journal-title":"Future Medicine"},{"key":"10.1016\/j.jconrel.2021.08.033_bb0180","doi-asserted-by":"crossref","first-page":"2736","DOI":"10.1039\/b922024k","article-title":"Nanoceria exhibit redox state-dependent catalase mimetic activity","volume":"46","author":"Pirmohamed","year":"2010","journal-title":"Chem. Commun."},{"key":"10.1016\/j.jconrel.2021.08.033_bb0185","doi-asserted-by":"crossref","first-page":"1056","DOI":"10.1039\/b615134e","article-title":"Superoxide dismutase mimetic properties exhibited by vacancy engineered ceria nanoparticles","author":"Korsvik","year":"2007","journal-title":"Chem. Commun."},{"key":"10.1016\/j.jconrel.2021.08.033_bb0190","doi-asserted-by":"crossref","first-page":"2705","DOI":"10.1016\/j.biomaterials.2008.03.014","article-title":"The role of cerium redox state in the SOD mimetic activity of nanoceria","volume":"29","author":"Heckert","year":"2008","journal-title":"Biomaterials."},{"key":"10.1016\/j.jconrel.2021.08.033_bb0195","doi-asserted-by":"crossref","first-page":"23342","DOI":"10.1021\/acsami.7b04761","article-title":"Quantitatively intrinsic biomimetic catalytic activity of nanocerias as radical scavengers and their ability against H2O2 and doxorubicin-induced oxidative stress","volume":"9","author":"Tian","year":"2017","journal-title":"ACS Appl. Mater. Interfaces"},{"key":"10.1016\/j.jconrel.2021.08.033_bb0200","doi-asserted-by":"crossref","first-page":"2308","DOI":"10.1002\/anie.200805279","article-title":"Oxidase-like activity of polymer-coated cerium oxide nanoparticles","volume":"48","author":"Asati","year":"2009","journal-title":"Angew. Chem. Int. Ed."},{"key":"10.1016\/j.jconrel.2021.08.033_bb0205","doi-asserted-by":"crossref","first-page":"1624","DOI":"10.1002\/adfm.201301649","article-title":"Nucleoside triphosphates as promoters to enhance nanoceria enzyme-like activity and for single-nucleotide polymorphism typing","volume":"24","author":"Xu","year":"2014","journal-title":"Adv. Funct. Mater."},{"key":"10.1016\/j.jconrel.2021.08.033_bb0210","doi-asserted-by":"crossref","first-page":"13562","DOI":"10.1039\/C6NR02730J","article-title":"Boosting the oxidase mimicking activity of nanoceria by fluoride capping: rivaling protein enzymes and ultrasensitive F\u2212 detection","volume":"8","author":"Liu","year":"2016","journal-title":"Nanoscale."},{"key":"10.1016\/j.jconrel.2021.08.033_bb0215","doi-asserted-by":"crossref","first-page":"17841","DOI":"10.1039\/C9NR05346H","article-title":"Fluoride-capped nanoceria as a highly efficient oxidase-mimicking nanozyme: inhibiting product adsorption and increasing oxygen vacancies","volume":"11","author":"Zhao","year":"2019","journal-title":"Nanoscale"},{"issue":"15","key":"10.1016\/j.jconrel.2021.08.033_bb0220","doi-asserted-by":"crossref","first-page":"2178","DOI":"10.1002\/cbic.202000049","article-title":"Promotion and Inhibition of the Oxidase-mimicking Activity of Nanoceria by Phosphate, Polyphosphate and DNA","volume":"21","author":"Zhao","year":"2020","journal-title":"ChemBioChem"},{"key":"10.1016\/j.jconrel.2021.08.033_bb0225","doi-asserted-by":"crossref","first-page":"8641","DOI":"10.1039\/C8CC04279A","article-title":"Remote activation of nanoparticulate biomimetic activity by light triggered pH-jump","volume":"54","author":"Yang\u00e1Liu","year":"2018","journal-title":"Chem. Commun."},{"key":"10.1016\/j.jconrel.2021.08.033_bb0230","doi-asserted-by":"crossref","first-page":"116","DOI":"10.1016\/j.biomaterials.2015.04.039","article-title":"Highly sensitive and robust peroxidase-like activity of porous nanorods of ceria and their application for breast cancer detection","volume":"59","author":"Tian","year":"2015","journal-title":"Biomaterials."},{"key":"10.1016\/j.jconrel.2021.08.033_bb0235","doi-asserted-by":"crossref","first-page":"409","DOI":"10.1002\/chem.201703833","article-title":"Peroxidase-mimicking nanozyme with enhanced activity and high stability based on metal\u2013support interactions","volume":"24","author":"Li","year":"2018","journal-title":"Chem. Eur. J."},{"key":"10.1016\/j.jconrel.2021.08.033_bb0240","doi-asserted-by":"crossref","first-page":"831","DOI":"10.1016\/j.jcis.2017.11.064","article-title":"Gold core\/ceria shell-based redox active nanozyme mimicking the biological multienzyme complex phenomenon","volume":"513","author":"Bhagat","year":"2018","journal-title":"J. Colloid Interface Sci."},{"key":"10.1016\/j.jconrel.2021.08.033_bb0245","doi-asserted-by":"crossref","first-page":"738","DOI":"10.1016\/j.nano.2010.05.004","article-title":"Phosphate ester hydrolysis of biologically relevant molecules by cerium oxide nanoparticles","volume":"6","author":"Kuchma","year":"2010","journal-title":"Nanomedicine"},{"key":"10.1016\/j.jconrel.2021.08.033_bb0250","doi-asserted-by":"crossref","first-page":"1742","DOI":"10.1039\/C7EN00394C","article-title":"Characterizing the phosphatase mimetic activity of cerium oxide nanoparticles and distinguishing its active site from that for catalase mimetic activity using anionic inhibitors","volume":"4","author":"Dhall","year":"2017","journal-title":"Environ Sci Nano."},{"key":"10.1016\/j.jconrel.2021.08.033_bb0255","doi-asserted-by":"crossref","first-page":"195","DOI":"10.1021\/acsami.8b17086","article-title":"Phosphatase-like activity of porous nanorods of CeO2 for the highly stabilized dephosphorylation under interferences","volume":"11","author":"Yao","year":"2018","journal-title":"ACS Appl. Mater. Interfaces"},{"key":"10.1016\/j.jconrel.2021.08.033_bb0260","doi-asserted-by":"crossref","first-page":"13215","DOI":"10.1039\/C9CC06782E","article-title":"Nanoceria as a DNase I mimicking nanozyme","volume":"55","author":"Xu","year":"2019","journal-title":"Chem. Commun."},{"key":"10.1016\/j.jconrel.2021.08.033_bb0265","doi-asserted-by":"crossref","first-page":"13074","DOI":"10.1039\/C8NR03556C","article-title":"CeO 2\u2212 x nanorods with intrinsic urease-like activity","volume":"10","author":"Korschelt","year":"2018","journal-title":"Nanoscale."},{"key":"10.1016\/j.jconrel.2021.08.033_bb0270","doi-asserted-by":"crossref","first-page":"6745","DOI":"10.1016\/j.biomaterials.2011.05.073","article-title":"A phosphate-dependent shift in redox state of cerium oxide nanoparticles and its effects on catalytic properties","volume":"32","author":"Singh","year":"2011","journal-title":"Biomaterials."},{"key":"10.1016\/j.jconrel.2021.08.033_bb0275","doi-asserted-by":"crossref","first-page":"1603","DOI":"10.1016\/j.freeradbiomed.2010.09.006","article-title":"Oxidative stress, inflammation, and cancer: how are they linked?","volume":"49","author":"Reuter","year":"2010","journal-title":"Free Radic. Biol. Med."},{"key":"10.1016\/j.jconrel.2021.08.033_bb0280","first-page":"1058","article-title":"Oxidative stress and diabetic complications","volume":"107","author":"Giacco","year":"2010","journal-title":"Circ Res. Am Heart Assoc"},{"key":"10.1016\/j.jconrel.2021.08.033_bb0285","doi-asserted-by":"crossref","first-page":"655","DOI":"10.1097\/00004872-200018060-00002","article-title":"Role of oxidative stress in cardiovascular diseases","volume":"18","author":"Dhalla","year":"2000","journal-title":"J. Hypertens."},{"key":"10.1016\/j.jconrel.2021.08.033_bb0290","series-title":"Antioxid Redox Signal","first-page":"765","article-title":"Downregulation of tumor growth and invasion by redox-active nanoparticles","volume":"19","author":"Alili","year":"2013"},{"key":"10.1016\/j.jconrel.2021.08.033_bb0295","doi-asserted-by":"crossref","first-page":"85","DOI":"10.1016\/j.cbi.2015.03.013","article-title":"Anti-cancer effects of cerium oxide nanoparticles and its intracellular redox activity","volume":"232","author":"Pe\u0161i\u0107","year":"2015","journal-title":"Chem Biol Interact."},{"key":"10.1016\/j.jconrel.2021.08.033_bb0300","doi-asserted-by":"crossref","first-page":"220","DOI":"10.1186\/s12885-016-2206-4","article-title":"Folic acid tagged nanoceria as a novel therapeutic agent in ovarian cancer","volume":"16","author":"Hijaz","year":"2016","journal-title":"BMC Cancer."},{"key":"10.1016\/j.jconrel.2021.08.033_bb0305","doi-asserted-by":"crossref","first-page":"875","DOI":"10.1021\/acs.molpharmaceut.6b01076","article-title":"Combination therapy of NSCLC using Hsp90 inhibitor and doxorubicin carrying functional nanoceria","volume":"14","author":"Sulthana","year":"2017","journal-title":"Mol Pharm."},{"key":"10.1016\/j.jconrel.2021.08.033_bb0310","doi-asserted-by":"crossref","first-page":"994","DOI":"10.1021\/acs.molpharmaceut.7b00920","article-title":"Targeted delivery and redox activity of folic acid-functionalized nanoceria in tumor cells","volume":"15","author":"Vassie","year":"2018","journal-title":"Mol Pharm."},{"key":"10.1016\/j.jconrel.2021.08.033_bb0315","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1038\/s41598-017-09876-w","article-title":"Nanoceria-mediated delivery of doxorubicin enhances the anti-tumour efficiency in ovarian cancer cells via apoptosis","volume":"7","author":"Das","year":"2017","journal-title":"Sci. Rep."},{"key":"10.1016\/j.jconrel.2021.08.033_bb0320","doi-asserted-by":"crossref","first-page":"1740","DOI":"10.1158\/1535-7163.MCT-13-0950","article-title":"Combination of conventional chemotherapeutics with redox-active cerium oxide nanoparticles\u2014A novel aspect in cancer therapy","volume":"13","author":"Sack","year":"2014","journal-title":"Mol. Cancer Ther."},{"key":"10.1016\/j.jconrel.2021.08.033_bb0325","doi-asserted-by":"crossref","first-page":"10375","DOI":"10.1039\/C7NR02770B","article-title":"Nanoparticle delivery of curcumin induces cellular hypoxia and ROS-mediated apoptosis via modulation of Bcl-2\/Bax in human neuroblastoma","volume":"9","author":"Kalashnikova","year":"2017","journal-title":"Nanoscale."},{"key":"10.1016\/j.jconrel.2021.08.033_bb0330","doi-asserted-by":"crossref","first-page":"4987","DOI":"10.1002\/jcp.27303","article-title":"Evaluation of anticancer effects of cerium oxide nanoparticles on mouse fibrosarcoma cell line","volume":"234","author":"Nourmohammadi","year":"2019","journal-title":"J. Cell. Physiol."},{"issue":"4","key":"10.1016\/j.jconrel.2021.08.033_bb0335","doi-asserted-by":"crossref","first-page":"1267","DOI":"10.1002\/hep.31139","article-title":"Bespoken nanoceria: A new effective treatment in experimental hepatocellular carcinoma","volume":"72","author":"Fern\u00e1ndez-Varo","year":"2020","journal-title":"Hepatology"},{"key":"10.1016\/j.jconrel.2021.08.033_bb0340","doi-asserted-by":"crossref","first-page":"2918","DOI":"10.1016\/j.biomaterials.2010.12.056","article-title":"Combined cytotoxic and anti-invasive properties of redox-active nanoparticles in tumor\u2013stroma interactions","volume":"32","author":"Alili","year":"2011","journal-title":"Biomaterials."},{"key":"10.1016\/j.jconrel.2021.08.033_bb0345","doi-asserted-by":"crossref","first-page":"3023","DOI":"10.2147\/IJN.S103648","article-title":"Cerium oxide nanoparticles inhibit the migration and proliferation of gastric cancer by increasing DHX15 expression","volume":"11","author":"Xiao","year":"2016","journal-title":"Int. J. Nanomedicine"},{"key":"10.1016\/j.jconrel.2021.08.033_bb0350","doi-asserted-by":"crossref","first-page":"1735","DOI":"10.1166\/jbn.2017.2452","article-title":"Efficacy of different compositions of cerium oxide nanoparticles in tumor-stroma interaction","volume":"13","author":"Sack-Zschauer","year":"2017","journal-title":"J. Biomed. Nanotechnol."},{"key":"10.1016\/j.jconrel.2021.08.033_bb0355","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0054578","article-title":"Nanoceria: a rare-earth nanoparticle as a novel anti-angiogenic therapeutic agent in ovarian cancer","volume":"8","author":"Giri","year":"2013","journal-title":"PLoS One"},{"key":"10.1016\/j.jconrel.2021.08.033_bb0360","doi-asserted-by":"crossref","first-page":"8808","DOI":"10.1016\/j.biomaterials.2013.07.083","article-title":"Anti-angiogenic activity of heparin functionalised cerium oxide nanoparticles","volume":"34","author":"Lord","year":"2013","journal-title":"Biomaterials."},{"key":"10.1016\/j.jconrel.2021.08.033_bb0365","doi-asserted-by":"crossref","first-page":"7746","DOI":"10.1016\/j.biomaterials.2012.07.019","article-title":"The induction of angiogenesis by cerium oxide nanoparticles through the modulation of oxygen in intracellular environments","volume":"33","author":"Das","year":"2012","journal-title":"Biomaterials."},{"key":"10.1016\/j.jconrel.2021.08.033_bb0370","article-title":"Revascularization and limb salvage following critical limb ischemia by nanoceria-induced Ref-1\/APE1-dependent angiogenesis","volume":"119919","author":"Park","year":"2020","journal-title":"Biomaterials."},{"key":"10.1016\/j.jconrel.2021.08.033_bb0375","doi-asserted-by":"crossref","first-page":"12646","DOI":"10.1002\/chem.201500868","article-title":"The Change in Antioxidant Properties of Dextran-Coated Redox Active Nanoparticles Due to Synergetic Photoreduction\u2013Oxidation","volume":"21","author":"Barkam","year":"2015","journal-title":"Chem Eur J."},{"key":"10.1016\/j.jconrel.2021.08.033_bb0380","doi-asserted-by":"crossref","first-page":"31510","DOI":"10.1021\/acsami.6b07338","article-title":"Nanoceria-mediated drug delivery for targeted photodynamic therapy on drug-resistant breast cancer","volume":"8","author":"Li","year":"2016","journal-title":"ACS Appl Mater Interfaces."},{"key":"10.1016\/j.jconrel.2021.08.033_bb0385","doi-asserted-by":"crossref","first-page":"8998","DOI":"10.1021\/acsnano.7b03507","article-title":"Regulating near-infrared photodynamic properties of semiconducting polymer nanotheranostics for optimized cancer therapy","volume":"11","author":"Zhu","year":"2017","journal-title":"ACS Nano."},{"key":"10.1016\/j.jconrel.2021.08.033_bb0390","doi-asserted-by":"crossref","first-page":"12629","DOI":"10.1021\/acsnano.8b07387","article-title":"Oxygen vacancies enhanced CeO2: Gd nanoparticles for sensing a tumor vascular microenvironment by magnetic resonance imaging","volume":"12","author":"Shao","year":"2018","journal-title":"ACS Nano."},{"key":"10.1016\/j.jconrel.2021.08.033_bb0395","doi-asserted-by":"crossref","first-page":"8017","DOI":"10.1039\/C9CC03763B","article-title":"Nanoceria decorated flower-like molybdenum sulphide nanoflakes: an efficient nanozyme for tumour selective ROS generation and photo thermal therapy","volume":"55","author":"Murugan","year":"2019","journal-title":"Chem Commun."},{"key":"10.1016\/j.jconrel.2021.08.033_bb0400","doi-asserted-by":"crossref","first-page":"2573","DOI":"10.1021\/nl052024f","article-title":"Vacancy engineered ceria nanostructures for protection from radiation-induced cellular damage","volume":"5","author":"Tarnuzzer","year":"2005","journal-title":"Nano Lett."},{"key":"10.1016\/j.jconrel.2021.08.033_bb0405","doi-asserted-by":"crossref","first-page":"15643","DOI":"10.1039\/C5NR03767K","article-title":"Cerium oxide nanoparticles, combining antioxidant and UV shielding properties, prevent UV-induced cell damage and mutagenesis","volume":"7","author":"Caputo","year":"2015","journal-title":"Nanoscale. R"},{"key":"10.1016\/j.jconrel.2021.08.033_bb0410","doi-asserted-by":"crossref","first-page":"225","DOI":"10.1016\/j.nano.2008.10.003","article-title":"Protection from radiation-induced pneumonitis using cerium oxide nanoparticles","volume":"5","author":"Colon","year":"2009","journal-title":"Nanomedicine"},{"key":"10.1016\/j.jconrel.2021.08.033_bb0415","doi-asserted-by":"crossref","first-page":"1510","DOI":"10.1159\/000443092","article-title":"Protective effects of cerium oxide nanoparticles on MC3T3-E1 osteoblastic cells exposed to X-ray irradiation","volume":"38","author":"Wang","year":"2016","journal-title":"Cell Physiol Biochem."},{"key":"10.1016\/j.jconrel.2021.08.033_bb0420","doi-asserted-by":"crossref","first-page":"631","DOI":"10.1016\/j.ejmp.2016.03.014","article-title":"Potential of using cerium oxide nanoparticles for protecting healthy tissue during accelerated partial breast irradiation (APBI)","volume":"32","author":"Ouyang","year":"2016","journal-title":"Phys Medica."},{"key":"10.1016\/j.jconrel.2021.08.033_bb0425","doi-asserted-by":"crossref","first-page":"516","DOI":"10.1667\/RR14261.1","article-title":"Cerium oxide nanoparticles: a potential medical countermeasure to mitigate radiation-induced lung injury in CBA\/J mice","volume":"185","author":"Xu","year":"2016","journal-title":"Radiat. Res."},{"key":"10.1016\/j.jconrel.2021.08.033_bb0430","doi-asserted-by":"crossref","first-page":"21069","DOI":"10.1039\/C8NR04640A","article-title":"Engineered nanoceria cytoprotection in vivo: mitigation of reactive oxygen species and double-stranded DNA breakage due to radiation exposure","volume":"10","author":"Das","year":"2018","journal-title":"Nanoscale"},{"key":"10.1016\/j.jconrel.2021.08.033_bb0435","doi-asserted-by":"crossref","first-page":"204","DOI":"10.4239\/wjd.v2.i11.204","article-title":"Biochemical and cellular evidence of the benefit of a combination of cerium oxide nanoparticles and selenium to diabetic rats","volume":"2","author":"Pourkhalili","year":"2011","journal-title":"World J. Diabetes"},{"key":"10.1016\/j.jconrel.2021.08.033_bb0440","first-page":"97","article-title":"Nanoceria attenuated high glucose-induced oxidative damage in HepG2 cells","volume":"18","author":"Shokrzadeh","year":"2016","journal-title":"Cell J."},{"key":"10.1016\/j.jconrel.2021.08.033_bb0445","doi-asserted-by":"crossref","first-page":"1905","DOI":"10.2217\/nnm-2018-0085","article-title":"Nanoceria suppresses multiple low doses of streptozotocin-induced Type 1 diabetes by inhibition of Nrf2\/NF-\u03baB pathway and reduction of apoptosis","volume":"13","author":"Khurana","year":"2018","journal-title":"Nanomedicine"},{"key":"10.1016\/j.jconrel.2021.08.033_bb0450","doi-asserted-by":"crossref","first-page":"9","DOI":"10.1113\/jphysiol.2007.135871","article-title":"Diabetes associated cell stress and dysfunction: role of mitochondrial and non-mitochondrial ROS production and activity","volume":"583","author":"Newsholme","year":"2007","journal-title":"J. Physiol."},{"key":"10.1016\/j.jconrel.2021.08.033_bb0455","doi-asserted-by":"crossref","first-page":"544","DOI":"10.1177\/0960327112468175","article-title":"Antiapoptotic effects of cerium oxide and yttrium oxide nanoparticles in isolated rat pancreatic islets","volume":"32","author":"Hosseini","year":"2013","journal-title":"Hum. Exp. Toxicol."},{"key":"10.1016\/j.jconrel.2021.08.033_bb0460","doi-asserted-by":"crossref","first-page":"136","DOI":"10.1016\/j.actbio.2015.01.017","article-title":"Antioxidant cerium oxide nanoparticle hydrogels for cellular encapsulation","volume":"16","author":"Weaver","year":"2015","journal-title":"Acta Biomater."},{"key":"10.1016\/j.jconrel.2021.08.033_bb0465","doi-asserted-by":"crossref","first-page":"7923","DOI":"10.1039\/C6NR00826G","article-title":"Hydrophilic CeO 2 nanocubes protect pancreatic \u03b2-cell line INS-1 from H 2 O 2-induced oxidative stress","volume":"8","author":"Lyu","year":"2016","journal-title":"Nanoscale."},{"key":"10.1016\/j.jconrel.2021.08.033_bb0470","doi-asserted-by":"crossref","first-page":"79","DOI":"10.1016\/j.jtemb.2017.02.013","article-title":"Protective effects of cerium oxide and yttrium oxide nanoparticles on reduction of oxidative stress induced by sub-acute exposure to diazinon in the rat pancreas","volume":"41","author":"Khaksar","year":"2017","journal-title":"J Trace Elem Med Biol. Elsevier"},{"key":"10.1016\/j.jconrel.2021.08.033_bb0475","doi-asserted-by":"crossref","first-page":"1805","DOI":"10.2217\/nnm-2018-0318","article-title":"Superoxide dismutase mimetic nanoceria restrains cerulein induced acute pancreatitis","volume":"14","author":"Khurana","year":"2019","journal-title":"Nanomedicine"},{"key":"10.1016\/j.jconrel.2021.08.033_bb0480","doi-asserted-by":"crossref","first-page":"1155","DOI":"10.1016\/j.freeradbiomed.2011.06.006","article-title":"Neuroprotective mechanisms of cerium oxide nanoparticles in a mouse hippocampal brain slice model of ischemia","volume":"51","author":"Estevez","year":"2011","journal-title":"Free Radic. Biol. Med."},{"key":"10.1016\/j.jconrel.2021.08.033_bb0485","doi-asserted-by":"crossref","first-page":"2743","DOI":"10.1007\/s12274-017-1478-6","article-title":"Biocompatible custom ceria nanoparticles against reactive oxygen species resolve acute inflammatory reaction after intracerebral hemorrhage","volume":"10","author":"Kang","year":"2017","journal-title":"Nano Res."},{"key":"10.1016\/j.jconrel.2021.08.033_bb0490","doi-asserted-by":"crossref","first-page":"2056","DOI":"10.1016\/j.actbio.2012.01.035","article-title":"Antibody-conjugated PEGylated cerium oxide nanoparticles for specific targeting of A\u03b2 aggregates modulate neuronal survival pathways","volume":"8","author":"Cimini","year":"2012","journal-title":"Acta Biomater."},{"key":"10.1016\/j.jconrel.2021.08.033_bb0495","doi-asserted-by":"crossref","first-page":"2860","DOI":"10.1021\/acsnano.5b08045","article-title":"Mitochondria-targeting ceria nanoparticles as antioxidants for Alzheimer\u2019s disease","volume":"10","author":"Kwon","year":"2016","journal-title":"ACS Nano"},{"key":"10.1016\/j.jconrel.2021.08.033_bb0500","doi-asserted-by":"crossref","first-page":"11039","DOI":"10.1002\/anie.201203780","article-title":"Ceria nanoparticles that can protect against ischemic stroke","volume":"51","author":"Kim","year":"2012","journal-title":"Angew. Chem. Int. Ed."},{"key":"10.1016\/j.jconrel.2021.08.033_bb0505","doi-asserted-by":"crossref","first-page":"10582","DOI":"10.1021\/nn403743b","article-title":"Custom cerium oxide nanoparticles protect against a free radical mediated autoimmune degenerative disease in the brain","volume":"7","author":"Heckman","year":"2013","journal-title":"ACS Nano"},{"key":"10.1016\/j.jconrel.2021.08.033_bb0510","doi-asserted-by":"crossref","first-page":"2311","DOI":"10.1016\/j.nano.2016.06.009","article-title":"Cerium oxide nanoparticles with antioxidant properties ameliorate strength and prolong life in mouse model of amyotrophic lateral sclerosis","volume":"12","author":"DeCoteau","year":"2016","journal-title":"Nanomedicine"},{"key":"10.1016\/j.jconrel.2021.08.033_bb0515","doi-asserted-by":"crossref","first-page":"151","DOI":"10.1016\/j.msec.2016.04.041","article-title":"Ceria-containing uncoated and coated hydroxyapatite-based galantamine nanocomposites for formidable treatment of Alzheimer\u2019s disease in ovariectomized albino-rat model","volume":"65","author":"Wahba","year":"2016","journal-title":"Mater. Sci. Eng. C"},{"key":"10.1016\/j.jconrel.2021.08.033_bb0520","first-page":"1159","article-title":"Cerium oxide nanoparticles promote neurogenesis and abrogate hypoxia-induced memory impairment through AMPK\u2013PKC\u2013CBP signaling cascade","volume":"11","author":"Arya","year":"2016","journal-title":"Int. J. Nanomedicine"},{"key":"10.1016\/j.jconrel.2021.08.033_bb0525","doi-asserted-by":"crossref","first-page":"1138","DOI":"10.1016\/j.ijbiomac.2017.05.180","article-title":"Cerium oxide nanoparticles promote HSA fibrillation in vitro","volume":"103","author":"Sekar","year":"2017","journal-title":"Int. J. Biol. Macromol."},{"key":"10.1016\/j.jconrel.2021.08.033_bb0530","doi-asserted-by":"crossref","first-page":"386","DOI":"10.1016\/j.bbagen.2016.11.022","article-title":"Gelatin\/nanoceria nanocomposite fibers as antioxidant scaffolds for neuronal regeneration","volume":"1861","author":"Marino","year":"2017","journal-title":"Biochim Biophys Acta (BBA)-General Subj"},{"key":"10.1016\/j.jconrel.2021.08.033_bb0535","doi-asserted-by":"crossref","first-page":"361","DOI":"10.1016\/j.neuint.2017.05.011","article-title":"Cerium oxide nanoparticles could ameliorate behavioral and neurochemical impairments in 6-hydroxydopamine induced Parkinson\u2019s disease in rats","volume":"108","author":"Hegazy","year":"2017","journal-title":"Neurochem. Int."},{"key":"10.1016\/j.jconrel.2021.08.033_bb0540","doi-asserted-by":"crossref","first-page":"6989","DOI":"10.2147\/IJN.S220380","article-title":"Cerium oxide NPs mitigate the amyloid formation of \u03b1-synuclein and associated cytotoxicity","volume":"14","author":"Zand","year":"2019","journal-title":"Int. J. Nanomedicine"},{"key":"10.1016\/j.jconrel.2021.08.033_bb0545","doi-asserted-by":"crossref","first-page":"9408","DOI":"10.1002\/anie.201805052","article-title":"Ceria nanoparticle systems for selective scavenging of mitochondrial, intracellular, and extracellular reactive oxygen species in Parkinson\u2019s disease","volume":"57","author":"Kwon","year":"2018","journal-title":"Angew. Chem. Int. Ed."},{"key":"10.1016\/j.jconrel.2021.08.033_bb0550","doi-asserted-by":"crossref","first-page":"6794","DOI":"10.1021\/acsnano.8b01994","article-title":"Simultaneous blood\u2013brain barrier crossing and protection for stroke treatment based on edaravone-loaded ceria nanoparticles","volume":"12","author":"Bao","year":"2018","journal-title":"ACS Nano"},{"key":"10.1016\/j.jconrel.2021.08.033_bb0555","doi-asserted-by":"crossref","first-page":"420","DOI":"10.1007\/s12031-018-1191-2","article-title":"Role of cerium oxide nanoparticles in a paraquat-induced model of oxidative stress: emergence of neuroprotective results in the brain","volume":"66","author":"Ranjbar","year":"2018","journal-title":"J. Mol. Neurosci."},{"key":"10.1016\/j.jconrel.2021.08.033_bb0560","doi-asserted-by":"crossref","first-page":"562","DOI":"10.3390\/biom9100562","article-title":"Antioxidant Enzyme-Mimetic Activity and Neuroprotective Effects of Cerium Oxide Nanoparticles Stabilized with Various Ratios of Citric Acid and EDTA","volume":"9","author":"Estevez","year":"2019","journal-title":"Biomolecules"},{"key":"10.1016\/j.jconrel.2021.08.033_bb0565","doi-asserted-by":"crossref","DOI":"10.1177\/1756286419859725","article-title":"Therapeutic effect on experimental acute cerebral infarction is enhanced after nanoceria labeling of human umbilical cord mesenchymal stem cells","volume":"12","author":"Zuo","year":"2019","journal-title":"Ther. Adv. Neurol. Disord."},{"key":"10.1016\/j.jconrel.2021.08.033_bb0570","doi-asserted-by":"crossref","first-page":"354","DOI":"10.1016\/j.nurt.2010.05.014","article-title":"Microglial activation and chronic neurodegeneration","volume":"7","author":"Lull","year":"2010","journal-title":"Neurotherapeutics"},{"key":"10.1016\/j.jconrel.2021.08.033_bb0575","doi-asserted-by":"crossref","first-page":"19437","DOI":"10.1039\/C9NR02648G","article-title":"Highly selective microglial uptake of ceria\u2013zirconia nanoparticles for enhanced analgesic treatment of neuropathic pain","volume":"11","author":"Choi","year":"2019","journal-title":"Nanoscale"},{"key":"10.1016\/j.jconrel.2021.08.033_bb0580","doi-asserted-by":"crossref","first-page":"235","DOI":"10.3390\/nano10020235","article-title":"Cerium oxide nanoparticles rescue \u03b1-synuclein-induced toxicity in a yeast model of parkinson\u2019s disease","volume":"10","author":"Ruotolo","year":"2020","journal-title":"Nanomaterials."},{"key":"10.1016\/j.jconrel.2021.08.033_bb0585","doi-asserted-by":"crossref","first-page":"3","DOI":"10.3390\/antiox8010003","article-title":"Suppression of light-induced oxidative stress in the retina by mitochondria-targeted antioxidant","volume":"8","author":"Baksheeva","year":"2019","journal-title":"Antioxidants"},{"key":"10.1016\/j.jconrel.2021.08.033_bb0590","doi-asserted-by":"crossref","first-page":"142","DOI":"10.1038\/nnano.2006.91","article-title":"Rare earth nanoparticles prevent retinal degeneration induced by intracellular peroxides","volume":"1","author":"Chen","year":"2006","journal-title":"Nat. Nanotechnol."},{"key":"10.1016\/j.jconrel.2021.08.033_bb0595","doi-asserted-by":"crossref","first-page":"8771","DOI":"10.1016\/j.biomaterials.2012.08.030","article-title":"Sustained protection against photoreceptor degeneration in tubby mice by intravitreal injection of nanoceria","volume":"33","author":"Cai","year":"2012","journal-title":"Biomaterials"},{"key":"10.1016\/j.jconrel.2021.08.033_bb0600","article-title":"Defining the catalytic activity of nanoceria in the P23H-1 rat, a photoreceptor degeneration model","volume":"10","author":"Wong","year":"2015","journal-title":"PLoS One"},{"key":"10.1016\/j.jconrel.2021.08.033_bb0605","first-page":"1176","article-title":"Non-toxic retention of nanoceria in murine eyes","volume":"22","author":"Cai","year":"2016","journal-title":"Mol. Vis."},{"key":"10.1016\/j.jconrel.2021.08.033_bb0610","doi-asserted-by":"crossref","first-page":"30","DOI":"10.1016\/j.exer.2019.03.003","article-title":"Retinal long term neuroprotection by Cerium Oxide nanoparticles after an acute damage induced by high intensity light exposure","volume":"182","author":"Tisi","year":"2019","journal-title":"Exp. Eye Res."},{"key":"10.1016\/j.jconrel.2021.08.033_bb0615","article-title":"Dually functional hollow ceria nanoparticle platform for intraocular drug delivery: A push beyond the limits of static and dynamic ocular barriers toward glaucoma therapy","volume":"119961","author":"Luo","year":"2020","journal-title":"Biomaterials."},{"key":"10.1016\/j.jconrel.2021.08.033_bb0620","doi-asserted-by":"crossref","first-page":"4669","DOI":"10.1021\/acsnano.7b00429","article-title":"Glycol chitosan engineered autoregenerative antioxidant significantly attenuates pathological damages in models of age-related macular degeneration","volume":"11","author":"Mitra","year":"2017","journal-title":"ACS Nano"},{"key":"10.1016\/j.jconrel.2021.08.033_bb0625","doi-asserted-by":"crossref","first-page":"13126","DOI":"10.1039\/C9NR02350J","article-title":"Autoregenerative redox nanoparticles as an antioxidant and glycation inhibitor for palliation of diabetic cataracts","volume":"11","author":"Zhou","year":"2019","journal-title":"Nanoscale."},{"key":"10.1016\/j.jconrel.2021.08.033_bb0630","doi-asserted-by":"crossref","first-page":"441","DOI":"10.3390\/molecules25030441","article-title":"Treatment of human lens epithelium with high levels of nanoceria leads to reactive oxygen species mediated apoptosis","volume":"25","author":"Hanafy","year":"2020","journal-title":"Molecules"},{"key":"10.1016\/j.jconrel.2021.08.033_bb0635","doi-asserted-by":"crossref","first-page":"549","DOI":"10.1016\/j.cardiores.2006.11.031","article-title":"Cardioprotective effects of cerium oxide nanoparticles in a transgenic murine model of cardiomyopathy","volume":"73","author":"Niu","year":"2007","journal-title":"Cardiovasc. Res."},{"key":"10.1016\/j.jconrel.2021.08.033_bb0640","doi-asserted-by":"crossref","first-page":"3767","DOI":"10.1021\/nn2048069","article-title":"Cerium oxide nanoparticles protect cardiac progenitor cells from oxidative stress","volume":"6","author":"Pagliari","year":"2012","journal-title":"ACS Nano"},{"key":"10.1016\/j.jconrel.2021.08.033_bb0645","doi-asserted-by":"crossref","first-page":"9951","DOI":"10.1016\/j.biomaterials.2014.08.037","article-title":"Cerium oxide nanoparticles attenuate monocrotaline induced right ventricular hypertrophy following pulmonary arterial hypertension","volume":"35","author":"Kolli","year":"2014","journal-title":"Biomaterials."},{"key":"10.1016\/j.jconrel.2021.08.033_bb0650","doi-asserted-by":"crossref","first-page":"89","DOI":"10.1016\/j.lfs.2018.03.045","article-title":"Cardioprotective effect of cerium oxide nanoparticles in monocrotaline rat model of pulmonary hypertension: A possible implication of endothelin-1","volume":"201","author":"Nassar","year":"2018","journal-title":"Life Sci."},{"key":"10.1016\/j.jconrel.2021.08.033_bb0655","doi-asserted-by":"crossref","first-page":"198","DOI":"10.1016\/j.jtemb.2018.07.011","article-title":"Cardioprotective effects of nanoceria in a murine model of cardiac remodeling","volume":"50","author":"Kumari","year":"2018","journal-title":"J. Trace Elem. Med. Biol."},{"key":"10.1016\/j.jconrel.2021.08.033_bb0660","doi-asserted-by":"crossref","first-page":"53","DOI":"10.1016\/j.jtemb.2018.01.016","article-title":"Nanoceria ameliorates doxorubicin induced cardiotoxicity: Possible mitigation via reduction of oxidative stress and inflammation","volume":"47","author":"Sangomla","year":"2018","journal-title":"J. Trace Elem. Med. Biol."},{"key":"10.1016\/j.jconrel.2021.08.033_bb0665","doi-asserted-by":"crossref","first-page":"691","DOI":"10.1016\/j.jhep.2015.10.020","article-title":"Cerium oxide nanoparticles reduce steatosis, portal hypertension and display anti-inflammatory properties in rats with liver fibrosis","volume":"64","author":"Or\u00f3","year":"2016","journal-title":"J. Hepatol."},{"key":"10.1016\/j.jconrel.2021.08.033_bb0670","doi-asserted-by":"crossref","first-page":"608","DOI":"10.1016\/j.biopha.2017.03.099","article-title":"Cerium dioxide nanoparticles possess anti-inflammatory properties in the conditions of the obesity-associated NAFLD in rats","volume":"90","author":"Kobyliak","year":"2017","journal-title":"Biomed. Pharmacother."},{"key":"10.1016\/j.jconrel.2021.08.033_bb0675","doi-asserted-by":"crossref","first-page":"1837","DOI":"10.1159\/000479540","article-title":"Prophylactic treatment with cerium oxide nanoparticles attenuate hepatic ischemia reperfusion injury in sprague dawley rats","volume":"42","author":"Manne","year":"2017","journal-title":"Cell. Physiol. Biochem."},{"key":"10.1016\/j.jconrel.2021.08.033_bb0680","doi-asserted-by":"crossref","DOI":"10.1002\/adma.201902956","article-title":"Ceria nanoparticles meet hepatic ischemia-reperfusion injury: the perfect imperfection","volume":"31","author":"Ni","year":"2019","journal-title":"Adv. Mater."},{"key":"10.1016\/j.jconrel.2021.08.033_bb0685","doi-asserted-by":"crossref","first-page":"75","DOI":"10.1186\/s12951-015-0135-z","article-title":"Cerium oxide nanoparticles attenuate acute kidney injury induced by intra-abdominal infection in Sprague\u2013Dawley rats","volume":"13","author":"Manne","year":"2015","journal-title":"J Nanobiotechnology."},{"key":"10.1016\/j.jconrel.2021.08.033_bb0690","doi-asserted-by":"crossref","first-page":"145","DOI":"10.1007\/s12011-018-1457-0","article-title":"Protective effect of nanoceria on cisplatin-induced nephrotoxicity by amelioration of oxidative stress and pro-inflammatory mechanisms","volume":"189","author":"Saifi","year":"2019","journal-title":"Biol. Trace Elem. Res."},{"issue":"6","key":"10.1016\/j.jconrel.2021.08.033_bb0695","doi-asserted-by":"crossref","first-page":"3563","DOI":"10.1021\/acsbiomaterials.9b01944","article-title":"Leveraging the Pathophysiological Alterations of Obstructive Nephropathy to Treat Renal Fibrosis by Cerium Oxide Nanoparticles","volume":"6","author":"Saifi","year":"2020","journal-title":"ACS Biomater Sci Eng"},{"key":"10.1016\/j.jconrel.2021.08.033_bb0700","first-page":"5515","article-title":"Cytotoxicity and antibacterial activity of gold-supported cerium oxide nanoparticles","volume":"9","author":"Babu","year":"2014","journal-title":"Int. J. Nanomedicine"},{"key":"10.1016\/j.jconrel.2021.08.033_bb0705","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1038\/srep38064","article-title":"Photodegradation of organic pollutants RhB dye using UV simulated sunlight on ceria based TiO 2 nanomaterials for antibacterial applications","volume":"6","author":"Kasinathan","year":"2016","journal-title":"Sci. Rep."},{"key":"10.1016\/j.jconrel.2021.08.033_bb0710","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1038\/srep45859","article-title":"pH-controlled cerium oxide nanoparticle inhibition of both gram-positive and gram-negative bacteria growth","volume":"7","author":"Alpaslan","year":"2017","journal-title":"Sci. Rep."},{"key":"10.1016\/j.jconrel.2021.08.033_bb0715","doi-asserted-by":"crossref","first-page":"467","DOI":"10.2217\/nnm-2019-0368","article-title":"Promising antiviral, antimicrobial and therapeutic properties of green nanoceria","volume":"15","author":"Mohamed","year":"2020","journal-title":"Nanomedicine."},{"key":"10.1016\/j.jconrel.2021.08.033_bb0720","first-page":"1427","article-title":"Cytoprotective effects of cerium and selenium nanoparticles on heat-shocked human dermal fibroblasts: an in vitro evaluation","volume":"11","author":"Yuan","year":"2016","journal-title":"Int. J. Nanomedicine"},{"key":"10.1016\/j.jconrel.2021.08.033_bb0725","doi-asserted-by":"crossref","first-page":"12202","DOI":"10.1021\/acs.langmuir.6b03022","article-title":"Redox-sensitive cerium oxide nanoparticles protect human keratinocytes from oxidative stress induced by glutathione depletion","volume":"32","author":"Singh","year":"2016","journal-title":"Langmuir."},{"key":"10.1016\/j.jconrel.2021.08.033_bb0730","doi-asserted-by":"crossref","first-page":"2194","DOI":"10.1016\/j.biomaterials.2012.11.061","article-title":"Effects of cerium oxide nanoparticles on the growth of keratinocytes, fibroblasts and vascular endothelial cells in cutaneous wound healing","volume":"34","author":"Chigurupati","year":"2013","journal-title":"Biomaterials"},{"key":"10.1016\/j.jconrel.2021.08.033_bb0735","doi-asserted-by":"crossref","first-page":"406","DOI":"10.1016\/j.msec.2016.05.103","article-title":"Cerium oxide nanoparticles stimulate proliferation of primary mouse embryonic fibroblasts in vitro","volume":"68","author":"Popov","year":"2016","journal-title":"Mater. Sci. Eng. C"},{"key":"10.1016\/j.jconrel.2021.08.033_bb0740","doi-asserted-by":"crossref","first-page":"1736","DOI":"10.1002\/jbm.a.35704","article-title":"Hyaluronan coated cerium oxide nanoparticles modulate CD44 and reactive oxygen species expression in human fibroblasts","volume":"104","author":"Lord","year":"2016","journal-title":"J Biomed Mater Res Part A"},{"key":"10.1016\/j.jconrel.2021.08.033_bb0745","doi-asserted-by":"crossref","first-page":"403","DOI":"10.2217\/nnm-2016-0342","article-title":"Cerium oxide nanoparticles: the regenerative redox machine in bioenergetic imbalance","volume":"12","author":"Pezzini","year":"2017","journal-title":"Nanomedicine."},{"key":"10.1016\/j.jconrel.2021.08.033_bb0750","doi-asserted-by":"crossref","first-page":"366","DOI":"10.1016\/j.msec.2017.08.013","article-title":"Cerium oxide nanoparticle-containing poly (\u03b5-caprolactone)\/gelatin electrospun film as a potential wound dressing material: In vitro and in vivo evaluation","volume":"81","author":"Naseri-Nosar","year":"2017","journal-title":"Mater. Sci. Eng. C"},{"key":"10.1016\/j.jconrel.2021.08.033_bb0755","doi-asserted-by":"crossref","first-page":"107","DOI":"10.1016\/j.jamcollsurg.2018.09.017","article-title":"Use of cerium oxide nanoparticles conjugated with microRNA-146a to correct the diabetic wound healing impairment","volume":"228","author":"Zgheib","year":"2019","journal-title":"J. Am. Coll. Surg."},{"key":"10.1016\/j.jconrel.2021.08.033_bb0760","doi-asserted-by":"crossref","first-page":"1725","DOI":"10.1016\/j.nano.2015.05.001","article-title":"Pilot in vivo investigation of cerium oxide nanoparticles as a novel anti-obesity pharmaceutical formulation","volume":"11","author":"Rocca","year":"2015","journal-title":"Nanomedicine"},{"key":"10.1016\/j.jconrel.2021.08.033_bb0765","doi-asserted-by":"crossref","first-page":"43","DOI":"10.1007\/s13167-017-0085-7","article-title":"Efficacy of nanoceria for periodontal tissues alteration in glutamate-induced obese rats\u2014multidisciplinary considerations for personalized dentistry and prevention","volume":"8","author":"Beregova","year":"2017","journal-title":"EPMA J."},{"key":"10.1016\/j.jconrel.2021.08.033_bb0770","doi-asserted-by":"crossref","first-page":"6820","DOI":"10.1021\/am4018863","article-title":"Attaching DNA to nanoceria: regulating oxidase activity and fluorescence quenching","volume":"5","author":"Pautler","year":"2013","journal-title":"ACS Appl. Mater. Interfaces"},{"key":"10.1016\/j.jconrel.2021.08.033_bb0775","doi-asserted-by":"crossref","first-page":"6215","DOI":"10.2147\/IJN.S89783","article-title":"Cerium oxide nanoparticle treatment ameliorates peritonitis-induced diaphragm dysfunction","volume":"10","author":"Asano","year":"2015","journal-title":"Int. J. Nanomedicine"},{"key":"10.1016\/j.jconrel.2021.08.033_bb0780","doi-asserted-by":"crossref","first-page":"1383","DOI":"10.1016\/j.biopha.2016.10.060","article-title":"Nanocrystalline cerium dioxide efficacy for prophylaxis of erosive and ulcerative lesions in the gastric mucosa of rats induced by stress","volume":"84","author":"Golyshkin","year":"2016","journal-title":"Biomed. Pharmacother."},{"key":"10.1016\/j.jconrel.2021.08.033_bb0785","doi-asserted-by":"crossref","first-page":"160","DOI":"10.1016\/j.biomaterials.2015.04.025","article-title":"Inhibition of MAP kinase\/NF-kB mediated signaling and attenuation of lipopolysaccharide induced severe sepsis by cerium oxide nanoparticles","volume":"59","author":"Selvaraj","year":"2015","journal-title":"Biomaterials."},{"key":"10.1016\/j.jconrel.2021.08.033_bb0790","doi-asserted-by":"crossref","first-page":"148","DOI":"10.1016\/j.msec.2017.11.014","article-title":"Biosynthesis of cerium oxide nanoparticles and their effect on lipopolysaccharide (LPS) induced sepsis mortality and associated hepatic dysfunction in male Sprague Dawley rats","volume":"83","author":"Chen","year":"2018","journal-title":"Mater. Sci. Eng. C"},{"key":"10.1016\/j.jconrel.2021.08.033_bb0795","doi-asserted-by":"crossref","first-page":"259","DOI":"10.1016\/j.freeradbiomed.2016.08.021","article-title":"Nanoceria restrains PM2. 5-induced metabolic disorder and hypothalamus inflammation by inhibition of astrocytes activation related NF-\u03baB pathway in Nrf2 deficient mice","volume":"99","author":"Xu","year":"2016","journal-title":"Free Radic. Biol. Med."},{"key":"10.1016\/j.jconrel.2021.08.033_bb0800","doi-asserted-by":"crossref","first-page":"13276","DOI":"10.1021\/acs.langmuir.6b03342","article-title":"Adsorption of nanoceria by phosphocholine liposomes","volume":"32","author":"Liu","year":"2016","journal-title":"Langmuir."},{"key":"10.1016\/j.jconrel.2021.08.033_bb0805","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.antiviral.2015.12.013","article-title":"Cerium dioxide nanoparticles increase immunogenicity of the influenza vaccine","volume":"127","author":"Zholobak","year":"2016","journal-title":"Antivir. Res."},{"key":"10.1016\/j.jconrel.2021.08.033_bb0810","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1038\/srep29197","article-title":"Cationic lipid-nanoceria hybrids, a novel nonviral vector-mediated gene delivery into mammalian cells: investigation of the cellular uptake mechanism","volume":"6","author":"Das","year":"2016","journal-title":"Sci. Rep."},{"key":"10.1016\/j.jconrel.2021.08.033_bb0815","first-page":"1","article-title":"Solid frustrated-Lewis-pair catalysts constructed by regulations on surface defects of porous nanorods of CeO 2","volume":"8","author":"Zhang","year":"2017","journal-title":"Nat. Commun."},{"key":"10.1016\/j.jconrel.2021.08.033_bb0820","doi-asserted-by":"crossref","first-page":"11283","DOI":"10.1021\/acsnano.7b05723","article-title":"Anionic cerium oxide nanoparticles protect plant photosynthesis from abiotic stress by scavenging reactive oxygen species","volume":"11","author":"Wu","year":"2017","journal-title":"ACS Nano"},{"key":"10.1016\/j.jconrel.2021.08.033_bb0825","doi-asserted-by":"crossref","first-page":"2454","DOI":"10.1021\/acs.langmuir.6b04421","article-title":"Protection of photosynthetic algae against ultraviolet radiation by one-step CeO2 shellization","volume":"33","author":"Duan","year":"2017","journal-title":"Langmuir."},{"key":"10.1016\/j.jconrel.2021.08.033_bb0830","doi-asserted-by":"crossref","first-page":"1062","DOI":"10.1177\/0885328216682362","article-title":"Incorporation of cerium oxide into hydroxyapatite coating regulates osteogenic activity of mesenchymal stem cell and macrophage polarization","volume":"31","author":"Li","year":"2017","journal-title":"J. Biomater. Appl."},{"key":"10.1016\/j.jconrel.2021.08.033_bb0835","doi-asserted-by":"crossref","first-page":"5","DOI":"10.2217\/nnm-2018-0515","article-title":"Protective effects of nanoceria in imiquimod induced psoriasis by inhibiting the inflammatory responses","volume":"15","author":"Domala","year":"2020","journal-title":"Nanomedicine"},{"key":"10.1016\/j.jconrel.2021.08.033_bb0840","first-page":"544","article-title":"Downregulation of tumor growth and invasion by redox-active nanoparticles","volume":"32","author":"Alili","year":"2016","journal-title":"Neurotherapeutics"},{"key":"10.1016\/j.jconrel.2021.08.033_bb0845","first-page":"285103","article-title":"Biocompatible custom ceria nanoparticles against reactive oxygen species resolve acute inflammatory reaction after intracerebral hemorrhage","volume":"1","author":"Perez","year":"2016","journal-title":"Biomaterials"},{"key":"10.1016\/j.jconrel.2021.08.033_bb0850","doi-asserted-by":"crossref","first-page":"6915","DOI":"10.1039\/c0cc01832e","article-title":"Multicolored redox active upconverter cerium oxide nanoparticle for bio-imaging and therapeutics","volume":"46","author":"Babu","year":"2010","journal-title":"Chem. Commun."},{"key":"10.1016\/j.jconrel.2021.08.033_bb0855","doi-asserted-by":"crossref","first-page":"770","DOI":"10.1039\/C5NR05924K","article-title":"Synthesis of porous NiO\/CeO 2 hybrid nanoflake arrays as a platform for electrochemical biosensing","volume":"8","author":"Cui","year":"2016","journal-title":"Nanoscale"},{"key":"10.1016\/j.jconrel.2021.08.033_bb0860","doi-asserted-by":"crossref","first-page":"121","DOI":"10.1016\/j.aca.2015.12.044","article-title":"Novel CeO2\u2013CuO-decorated enzymatic lactate biosensors operating in low oxygen environments","volume":"909","author":"Uzunoglu","year":"2016","journal-title":"Anal. Chim. Acta"},{"key":"10.1016\/j.jconrel.2021.08.033_bb0865","doi-asserted-by":"crossref","first-page":"11","DOI":"10.1016\/j.talanta.2016.04.050","article-title":"Ultrasensitive electrochemical immunosensor for quantitative detection of tumor specific growth factor by using Ag@ CeO2 nanocomposite as labels","volume":"156","author":"Yu","year":"2016","journal-title":"Talanta."},{"key":"10.1016\/j.jconrel.2021.08.033_bb0870","doi-asserted-by":"crossref","first-page":"457","DOI":"10.1016\/j.bios.2016.05.040","article-title":"Polyacrylic acid-coated cerium oxide nanoparticles: an oxidase mimic applied for colorimetric assay to organophosphorus pesticides","volume":"85","author":"Zhang","year":"2016","journal-title":"Biosens. Bioelectron."},{"key":"10.1016\/j.jconrel.2021.08.033_bb0875","doi-asserted-by":"crossref","first-page":"57","DOI":"10.1016\/j.cbi.2016.04.035","article-title":"In vitro skin decontamination of the organophosphorus pesticide Paraoxon with nanometric cerium oxide CeO2","volume":"267","author":"Salerno","year":"2017","journal-title":"Chem. Biol. Interact."},{"key":"10.1016\/j.jconrel.2021.08.033_bb0880","doi-asserted-by":"crossref","first-page":"66","DOI":"10.1007\/s00604-018-3175-x","article-title":"Fluorometric determination of pesticides and organophosphates using nanoceria as a phosphatase mimic and an inner filter effect on carbon nanodots","volume":"186","author":"Wei","year":"2019","journal-title":"Microchim. Acta"},{"key":"10.1016\/j.jconrel.2021.08.033_bb0885","doi-asserted-by":"crossref","first-page":"1412","DOI":"10.1002\/anie.201510355","article-title":"Vacancy-engineered nanoceria: enzyme mimetic hotspots for the degradation of nerve agents","volume":"55","author":"Vernekar","year":"2016","journal-title":"Angew. Chem. Int. Ed."},{"key":"10.1016\/j.jconrel.2021.08.033_bb0890","doi-asserted-by":"crossref","first-page":"5455","DOI":"10.1039\/C9CP00179D","article-title":"Shape-selective synthesis of nanoceria for degradation of paraoxon as a chemical warfare simulant","volume":"21","author":"Trenque","year":"2019","journal-title":"Phys. Chem. Chem. Phys."},{"key":"10.1016\/j.jconrel.2021.08.033_bb0895","doi-asserted-by":"crossref","first-page":"15871","DOI":"10.1021\/acs.langmuir.8b03335","article-title":"DNA-Functionalized Nanoceria for Probing Oxidation of Phosphorus Compounds","volume":"34","author":"Wang","year":"2018","journal-title":"Langmuir."},{"key":"10.1016\/j.jconrel.2021.08.033_bb0900","doi-asserted-by":"crossref","first-page":"1290","DOI":"10.1021\/ja511444e","article-title":"Hydrogen peroxide displacing DNA from nanoceria: mechanism and detection of glucose in serum","volume":"137","author":"Liu","year":"2015","journal-title":"J. Am. Chem. Soc."},{"key":"10.1016\/j.jconrel.2021.08.033_bb0905","doi-asserted-by":"crossref","first-page":"112","DOI":"10.1016\/j.talanta.2016.04.067","article-title":"A single use electrochemical sensor based on biomimetic nanoceria for the detection of wine antioxidants","volume":"156","author":"Andrei","year":"2016","journal-title":"Talanta."},{"key":"10.1016\/j.jconrel.2021.08.033_bb0910","doi-asserted-by":"crossref","first-page":"822","DOI":"10.1002\/adhm.201500705","article-title":"ssDNA-functionalized nanoceria: a redox-active aptaswitch for biomolecular recognition","volume":"5","author":"B\u00fclb\u00fcl","year":"2016","journal-title":"Adv Healthc Mater"},{"key":"10.1016\/j.jconrel.2021.08.033_bb0915","doi-asserted-by":"crossref","first-page":"13349","DOI":"10.1021\/acs.analchem.7b03502","article-title":"Cu\/Mn double-doped CeO2 nanocomposites as signal tags and signal amplifiers for sensitive electrochemical detection of procalcitonin","volume":"89","author":"Yang","year":"2017","journal-title":"Anal. Chem."},{"key":"10.1016\/j.jconrel.2021.08.033_bb0920","doi-asserted-by":"crossref","first-page":"12210","DOI":"10.1021\/acsnano.7b05518","article-title":"Enzyme-mimetic antioxidant luminescent nanoparticles for highly sensitive hydrogen peroxide biosensing","volume":"11","author":"Pratsinis","year":"2017","journal-title":"ACS Nano"},{"key":"10.1016\/j.jconrel.2021.08.033_bb0925","doi-asserted-by":"crossref","first-page":"402","DOI":"10.1016\/j.bios.2016.10.087","article-title":"A new sight for detecting the ADRB1 gene mutation to guide a therapeutic regimen for hypertension based on a CeO2-doped nanoprobe","volume":"92","author":"Zhao","year":"2017","journal-title":"Biosens. Bioelectron."},{"key":"10.1016\/j.jconrel.2021.08.033_bb0930","doi-asserted-by":"crossref","first-page":"94","DOI":"10.1016\/j.bios.2017.11.014","article-title":"Cerium dioxide-doped carboxyl fullerene as novel nanoprobe and catalyst in electrochemical biosensor for amperometric detection of the CYP2C19* 2 allele in human serum","volume":"102","author":"Zhang","year":"2018","journal-title":"Biosens. Bioelectron."},{"key":"10.1016\/j.jconrel.2021.08.033_bb0935","doi-asserted-by":"crossref","first-page":"100","DOI":"10.1016\/j.talanta.2018.06.034","article-title":"Mimicking peroxidase activity of Co2 (OH) 2CO3-CeO2 nanocomposite for smartphone based detection of tumor marker using paper-based microfluidic immunodevice","volume":"189","author":"Alizadeh","year":"2018","journal-title":"Talanta."},{"key":"10.1016\/j.jconrel.2021.08.033_bb0940","doi-asserted-by":"crossref","first-page":"265","DOI":"10.1016\/j.aca.2017.08.018","article-title":"Fluorescence resonance energy transfer aptasensor between nanoceria and graphene quantum dots for the determination of ochratoxin A","volume":"1000","author":"Tian","year":"2018","journal-title":"Anal Chim Acta."},{"key":"10.1016\/j.jconrel.2021.08.033_bb0945","doi-asserted-by":"crossref","first-page":"285","DOI":"10.1016\/j.talanta.2017.09.091","article-title":"A fluorescent \u201con-off-on\u201d probe for sensitive detection of ATP based on ATP displacing DNA from nanoceria","volume":"179","author":"Li","year":"2018","journal-title":"Talanta"},{"key":"10.1016\/j.jconrel.2021.08.033_bb0950","doi-asserted-by":"crossref","first-page":"2684","DOI":"10.1021\/acssensors.8b01193","article-title":"High sensitivity plasmonic sensing of hydrogen over a broad dynamic range using catalytic Au-CeO2 Thin Film nanocomposites","volume":"3","author":"Houlihan","year":"2018","journal-title":"ACS sensors."},{"key":"10.1016\/j.jconrel.2021.08.033_bb0955","doi-asserted-by":"crossref","first-page":"449","DOI":"10.1021\/acs.nanolett.8b04253","article-title":"Enzyme-free plasmonic biosensor for direct detection of neurotransmitter dopamine from whole blood","volume":"19","author":"V\u00e1zquez-Guardado","year":"2018","journal-title":"Nano Lett."},{"key":"10.1016\/j.jconrel.2021.08.033_bb0960","doi-asserted-by":"crossref","first-page":"274","DOI":"10.1007\/s00604-019-3382-0","article-title":"A colorimetric heparin assay based on the inhibition of the oxidase mimicking activity of cerium oxide nanoparticles","volume":"186","author":"Liao","year":"2019","journal-title":"Microchim. Acta"},{"issue":"2","key":"10.1016\/j.jconrel.2021.08.033_bb0965","doi-asserted-by":"crossref","first-page":"2339","DOI":"10.1021\/acs.analchem.9b05593","article-title":"Nanoceria-templated metal organic frameworks with oxidase-mimicking activity boosted by hexavalent chromium","volume":"92","author":"Wang","year":"2019","journal-title":"Anal. Chem."},{"key":"10.1016\/j.jconrel.2021.08.033_bb0970","doi-asserted-by":"crossref","first-page":"107","DOI":"10.1002\/tox.20704","article-title":"Bio-distribution and in vivo antioxidant effects of cerium oxide nanoparticles in mice","volume":"28","author":"Hirst","year":"2013","journal-title":"Environ Toxicol."},{"key":"10.1016\/j.jconrel.2021.08.033_bb0975","doi-asserted-by":"crossref","first-page":"561","DOI":"10.1039\/C4EN00034J","article-title":"Bioavailability, distribution and clearance of tracheally instilled, gavaged or injected cerium dioxide nanoparticles and ionic cerium","volume":"1","author":"Molina","year":"2014","journal-title":"Environ Sci Nano"},{"key":"10.1016\/j.jconrel.2021.08.033_bb0980","doi-asserted-by":"crossref","first-page":"398","DOI":"10.1016\/j.nano.2012.08.002","article-title":"Biodistribution and biopersistence of ceria engineered nanomaterials: size dependence","volume":"9","author":"Yokel","year":"2013","journal-title":"Nanomedicine"},{"key":"10.1016\/j.jconrel.2021.08.033_bb0985","doi-asserted-by":"crossref","first-page":"549","DOI":"10.1039\/C4EN00035H","article-title":"Nanoceria biodistribution and retention in the rat after its intravenous administration are not greatly influenced by dosing schedule, dose, or particle shape","volume":"1","author":"Yokel","year":"2014","journal-title":"Environ Sci Nano"},{"key":"10.1016\/j.jconrel.2021.08.033_bb0990","doi-asserted-by":"crossref","first-page":"406","DOI":"10.1039\/C4EN00039K","article-title":"The yin: an adverse health perspective of nanoceria: uptake, distribution, accumulation, and mechanisms of its toxicity","volume":"1","author":"Yokel","year":"2014","journal-title":"Environ Sci Nano."},{"key":"10.1016\/j.jconrel.2021.08.033_bb0995","doi-asserted-by":"crossref","first-page":"5820","DOI":"10.1021\/nn302235u","article-title":"Cerium dioxide nanoparticles induce apoptosis and autophagy in human peripheral blood monocytes","volume":"6","author":"Hussain","year":"2012","journal-title":"ACS Nano"},{"key":"10.1016\/j.jconrel.2021.08.033_bb1000","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1038\/s41598-017-09430-8","article-title":"Cerium oxide nanoparticles inhibit differentiation of neural stem cells","volume":"7","author":"Gliga","year":"2017","journal-title":"Sci. Rep."},{"key":"10.1016\/j.jconrel.2021.08.033_bb1005","doi-asserted-by":"crossref","first-page":"466","DOI":"10.1039\/C4EN00096J","article-title":"Metabolomic effects in HepG2 cells exposed to four TiO 2 and two CeO 2 nanomaterials","volume":"1","author":"Kitchin","year":"2014","journal-title":"Environ Sci Nano"},{"key":"10.1016\/j.jconrel.2021.08.033_bb1010","doi-asserted-by":"crossref","first-page":"285103","DOI":"10.1088\/0957-4484\/21\/28\/285103","article-title":"Lung deposition and extrapulmonary translocation of nano-ceria after intratracheal instillation","volume":"21","author":"He","year":"2010","journal-title":"Nanotechnology"},{"key":"10.1016\/j.jconrel.2021.08.033_bb1015","doi-asserted-by":"crossref","first-page":"2327","DOI":"10.2147\/IJN.S25119","article-title":"Intratracheal instillation of cerium oxide nanoparticles induces hepatic toxicity in male Sprague-Dawley rats","volume":"6","author":"Nalabotu","year":"2011","journal-title":"Int. J. Nanomedicine"},{"key":"10.1016\/j.jconrel.2021.08.033_bb1020","doi-asserted-by":"crossref","first-page":"173","DOI":"10.1016\/j.taap.2012.02.008","article-title":"Alteration of hepatic structure and oxidative stress induced by intravenous nanoceria","volume":"260","author":"Tseng","year":"2012","journal-title":"Toxicol. Appl. Pharmacol."},{"key":"10.1016\/j.jconrel.2021.08.033_bb1025","doi-asserted-by":"crossref","first-page":"255","DOI":"10.1016\/j.taap.2012.05.005","article-title":"Induction of pulmonary fibrosis by cerium oxide nanoparticles","volume":"262","author":"Ma","year":"2012","journal-title":"Toxicol. Appl. Pharmacol."},{"key":"10.1016\/j.jconrel.2021.08.033_bb1030","doi-asserted-by":"crossref","first-page":"3725","DOI":"10.1021\/es103309n","article-title":"Nano-CeO2 exhibits adverse effects at environmental relevant concentrations","volume":"45","author":"Zhang","year":"2011","journal-title":"Environ. Sci. Technol."},{"key":"10.1016\/j.jconrel.2021.08.033_bb1035","doi-asserted-by":"crossref","first-page":"459","DOI":"10.1039\/C4EN00025K","article-title":"Effect of cerium oxide nanoparticles on asparagus lettuce cultured in an agar medium","volume":"1","author":"Cui","year":"2014","journal-title":"Environ Sci Nano"},{"key":"10.1016\/j.jconrel.2021.08.033_bb1040","doi-asserted-by":"crossref","first-page":"437","DOI":"10.1016\/B978-0-12-812792-6.00017-0","article-title":"Nanotoxicology: toxicity and risk assessment of nanomaterials","author":"Saifi","year":"2018","journal-title":"Nanomater Chromatogr"},{"key":"10.1016\/j.jconrel.2021.08.033_bb1045","doi-asserted-by":"crossref","first-page":"4855","DOI":"10.1021\/nn305872d","article-title":"Cellular interaction and toxicity depend on physicochemical properties and surface modification of redox-active nanomaterials","volume":"7","author":"Dowding","year":"2013","journal-title":"ACS Nano"},{"key":"10.1016\/j.jconrel.2021.08.033_bb1050","doi-asserted-by":"crossref","first-page":"136","DOI":"10.1016\/j.tiv.2016.09.022","article-title":"Impact of cerium oxide nanoparticles shape on their in vitro cellular toxicity","volume":"38","author":"Forest","year":"2017","journal-title":"Toxicol. in Vitro"},{"key":"10.1016\/j.jconrel.2021.08.033_bb1055","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1038\/srep15613","article-title":"Untangling the biological effects of cerium oxide nanoparticles: the role of surface valence states","volume":"5","author":"Pulido-Reyes","year":"2015","journal-title":"Sci. Rep."},{"key":"10.1016\/j.jconrel.2021.08.033_bb1060","doi-asserted-by":"crossref","first-page":"992","DOI":"10.3109\/17435390.2016.1157220","article-title":"Evaluation of the effect of valence state on cerium oxide nanoparticle toxicity following intratracheal instillation in rats","volume":"10","author":"Dunnick","year":"2016","journal-title":"Nanotoxicology"},{"key":"10.1016\/j.jconrel.2021.08.033_bb1065","doi-asserted-by":"crossref","first-page":"40","DOI":"10.1086\/689590","article-title":"Protein corona modulates uptake and toxicity of nanoceria via clathrin-mediated endocytosis","volume":"231","author":"Mazzolini","year":"2016","journal-title":"Biol. Bull."},{"key":"10.1016\/j.jconrel.2021.08.033_bb1070","doi-asserted-by":"crossref","first-page":"2623","DOI":"10.2217\/nnm-2017-0205","article-title":"Synergistic role of nanoceria on the ability of tobacco smoke to induce carcinogenic hallmarks in lung epithelial cells","volume":"12","author":"Rubio","year":"2017","journal-title":"Nanomedicine."},{"key":"10.1016\/j.jconrel.2021.08.033_bb1075","doi-asserted-by":"crossref","first-page":"2121","DOI":"10.1021\/nn800511k","article-title":"Comparison of the mechanism of toxicity of zinc oxide and cerium oxide nanoparticles based on dissolution and oxidative stress properties","volume":"2","author":"Xia","year":"2008","journal-title":"ACS Nano"},{"key":"10.1016\/j.jconrel.2021.08.033_bb1080","doi-asserted-by":"crossref","first-page":"2139","DOI":"10.1166\/jbn.2016.2320","article-title":"Decreased uptake and enhanced mitochondrial protection underlie reduced toxicity of nanoceria in human monocyte-derived macrophages","volume":"12","author":"Hussain","year":"2016","journal-title":"J. Biomed. Nanotechnol."},{"key":"10.1016\/j.jconrel.2021.08.033_bb1085","doi-asserted-by":"crossref","first-page":"3836","DOI":"10.1021\/acsnano.8b01086","article-title":"Toxicological profiling of metal oxide nanoparticles in liver context reveals pyroptosis in Kupffer cells and macrophages versus apoptosis in hepatocytes","volume":"12","author":"Mirshafiee","year":"2018","journal-title":"ACS Nano"},{"key":"10.1016\/j.jconrel.2021.08.033_bb1090","doi-asserted-by":"crossref","first-page":"69","DOI":"10.1016\/j.biopha.2017.05.064","article-title":"Anti-inflammatory and antioxidant effect of cerium dioxide nanoparticles immobilized on the surface of silica nanoparticles in rat experimental pneumonia","volume":"92","author":"Serebrovska","year":"2017","journal-title":"Biomed. Pharmacother."},{"key":"10.1016\/j.jconrel.2021.08.033_bb1095","doi-asserted-by":"crossref","first-page":"63","DOI":"10.1016\/j.taap.2015.07.012","article-title":"Effects of amorphous silica coating on cerium oxide nanoparticles induced pulmonary responses","volume":"288","author":"Ma","year":"2015","journal-title":"Toxicol. Appl. Pharmacol."},{"key":"10.1016\/j.jconrel.2021.08.033_bb1100","doi-asserted-by":"crossref","first-page":"100982","DOI":"10.1016\/j.nantod.2020.100982","article-title":"Nanoceria as a possible agent for the management of COVID-19","volume":"35","author":"Allawadhi","year":"2020","journal-title":"Nano Today"}],"container-title":["Journal of Controlled Release"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0168365921004399?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0168365921004399?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,9,29]],"date-time":"2025-09-29T16:02:41Z","timestamp":1759161761000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0168365921004399"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,10]]},"references-count":220,"alternative-id":["S0168365921004399"],"URL":"https:\/\/doi.org\/10.1016\/j.jconrel.2021.08.033","relation":{},"ISSN":["0168-3659"],"issn-type":[{"value":"0168-3659","type":"print"}],"subject":[],"published":{"date-parts":[[2021,10]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Nanoceria, the versatile nanoparticles: Promising biomedical applications","name":"articletitle","label":"Article Title"},{"value":"Journal of Controlled Release","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.jconrel.2021.08.033","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2021 Elsevier B.V. All rights reserved.","name":"copyright","label":"Copyright"}]}}