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Chem."},{"key":"10.1016\/j.jconrel.2022.09.065_bb0340","doi-asserted-by":"crossref","first-page":"1152","DOI":"10.1172\/JCI81129","article-title":"Extracellular vesicle isolation and characterization: toward clinical application","volume":"126","author":"Xu","year":"2016","journal-title":"J. Clin. 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Sci."},{"key":"10.1016\/j.jconrel.2022.09.065_bb0685","doi-asserted-by":"crossref","first-page":"1922","DOI":"10.1080\/10717544.2018.1502839","article-title":"Primary M1 macrophages as multifunctional carrier combined with PLGA nanoparticle delivering anticancer drug for efficient glioma therapy","volume":"25","author":"Pang","year":"2018","journal-title":"Drug Deliv."},{"key":"10.1016\/j.jconrel.2022.09.065_bb0690","doi-asserted-by":"crossref","first-page":"79","DOI":"10.1016\/j.biomaterials.2017.06.017","article-title":"Macrophages with cellular backpacks for targeted drug delivery to the brain","volume":"140","author":"Klyachko","year":"2017","journal-title":"Biomaterials"},{"key":"10.1016\/j.jconrel.2022.09.065_bb0695","doi-asserted-by":"crossref","first-page":"2100701","DOI":"10.1002\/adma.202100701","article-title":"A noninvasive gut-to-brain oral drug delivery system for treating brain tumors","volume":"33","author":"Miao","year":"2021","journal-title":"Adv. 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Mater."},{"key":"10.1016\/j.jconrel.2022.09.065_bb0710","doi-asserted-by":"crossref","first-page":"1900259","DOI":"10.1002\/adfm.201900259","article-title":"Nanoparticles surmounting blood\u2013brain tumor barrier through both transcellular and paracellular pathways to target brain metastases","volume":"29","author":"Miao","year":"2019","journal-title":"Adv. Funct. Mater."},{"key":"10.1016\/j.jconrel.2022.09.065_bb0715","doi-asserted-by":"crossref","first-page":"2102274","DOI":"10.1002\/adfm.202102274","article-title":"Biodegradable polymeric nanoparticles containing an immune checkpoint inhibitor (aPDL1) to locally induce immune responses in the central nervous system","volume":"31","author":"Zhang","year":"2021","journal-title":"Adv. Funct. Mater."},{"key":"10.1016\/j.jconrel.2022.09.065_bb0720","doi-asserted-by":"crossref","first-page":"199","DOI":"10.3390\/ph13080199","article-title":"A systematic review of molecular imaging agents targeting bradykinin B1 and B2 receptors","volume":"13","author":"Lau","year":"2020","journal-title":"Pharmaceuticals"},{"key":"10.1016\/j.jconrel.2022.09.065_bb0725","first-page":"408","article-title":"Lymphocyte adhesion and transendothelial migration in the central nervous system: the role of LFA-1, ICAM-1, VLA-4 and VCAM-1. off","volume":"86","author":"Greenwood","year":"1995","journal-title":"Immunology"},{"key":"10.1016\/j.jconrel.2022.09.065_bb0730","doi-asserted-by":"crossref","first-page":"48","DOI":"10.1016\/j.biomaterials.2019.04.026","article-title":"Scaffolds biomimicking macrophages for a glioblastoma NIR-Ib imaging guided photothermal therapeutic strategy by crossing Blood-Brain Barrier","volume":"211","author":"Lai","year":"2019","journal-title":"Biomaterials"},{"key":"10.1016\/j.jconrel.2022.09.065_bb0735","doi-asserted-by":"crossref","first-page":"11452","DOI":"10.1021\/acsnano.0c03824","article-title":"Natural-killer-cell-inspired nanorobots with aggregation-induced emission characteristics for near-infrared-II fluorescence-guided glioma theranostics","volume":"14","author":"Deng","year":"2020","journal-title":"ACS Nano"},{"key":"10.1016\/j.jconrel.2022.09.065_bb0740","doi-asserted-by":"crossref","first-page":"269","DOI":"10.1007\/s00280-015-2926-1","article-title":"Brain tumor-targeted delivery and therapy by focused ultrasound introduced doxorubicin-loaded cationic liposomes","volume":"77","author":"Lin","year":"2016","journal-title":"Cancer Chemother. 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Sci."},{"key":"10.1016\/j.jconrel.2022.09.065_bb0760","doi-asserted-by":"crossref","first-page":"11144","DOI":"10.1021\/acsami.8b22468","article-title":"Enhancing boron uptake in brain glioma by a boron-polymer\/microbubble complex with focused ultrasound","volume":"11","author":"Fan","year":"2019","journal-title":"ACS Appl. Mater. Interfaces"},{"key":"10.1016\/j.jconrel.2022.09.065_bb0765","doi-asserted-by":"crossref","first-page":"72","DOI":"10.1016\/j.jconrel.2016.05.052","article-title":"Non-invasive, neuron-specific gene therapy by focused ultrasound-induced blood-brain barrier opening in Parkinson's disease mouse model","volume":"235","author":"Lin","year":"2016","journal-title":"J. Control. 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Lett."},{"key":"10.1016\/j.jconrel.2022.09.065_bb0820","doi-asserted-by":"crossref","first-page":"13","DOI":"10.1007\/s10014-010-0007-z","article-title":"Angiogenesis and invasion in glioma","volume":"28","author":"Onishi","year":"2011","journal-title":"Brain Tumor Pathol."},{"key":"10.1016\/j.jconrel.2022.09.065_bb0825","doi-asserted-by":"crossref","first-page":"1046","DOI":"10.1016\/j.biocel.2004.01.013","article-title":"Microregional extracellular matrix heterogeneity in brain modulates glioma cell invasion","volume":"36","author":"Bellail","year":"2004","journal-title":"Int. J. Biochem. Cell Biol."},{"key":"10.1016\/j.jconrel.2022.09.065_bb0830","doi-asserted-by":"crossref","first-page":"2157","DOI":"10.3390\/ijms18102157","article-title":"TGF-beta-induced endothelial-mesenchymal transition in fibrotic diseases","volume":"18","author":"Pardali","year":"2017","journal-title":"Int. J. Mol. Sci."},{"key":"10.1016\/j.jconrel.2022.09.065_bb0835","doi-asserted-by":"crossref","first-page":"254","DOI":"10.1093\/neuonc\/nou218","article-title":"Differential regulation of TGF-beta-induced, ALK-5-mediated VEGF release by SMAD2\/3 versus SMAD1\/5\/8 signaling in glioblastoma","volume":"17","author":"Seystahl","year":"2015","journal-title":"Neuro-Oncol."},{"key":"10.1016\/j.jconrel.2022.09.065_bb0840","doi-asserted-by":"crossref","DOI":"10.1101\/cshperspect.a002915","article-title":"Interplay of cadherin-mediated cell adhesion and canonical wnt signaling","volume":"2","author":"Heuberger","year":"2010","journal-title":"Cold Spring Harb. Perspect. Biol."},{"key":"10.1016\/j.jconrel.2022.09.065_bb0845","doi-asserted-by":"crossref","first-page":"776","DOI":"10.1038\/nature05571","article-title":"Dll4 signalling through Notch1 regulates formation of tip cells during angiogenesis","volume":"445","author":"Hellstroem","year":"2007","journal-title":"Nature"},{"key":"10.1016\/j.jconrel.2022.09.065_bb0850","doi-asserted-by":"crossref","first-page":"1134","DOI":"10.1161\/ATVBAHA.114.304741","article-title":"Endothelial Jagged1 antagonizes Dll4 regulation of endothelial branching and promotes vascular maturation downstream of Dll4\/Notch1","volume":"35","author":"Pedrosa","year":"2015","journal-title":"Arterioscler. Thromb. Vasc. 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Med."},{"key":"10.1016\/j.jconrel.2022.09.065_bb0885","doi-asserted-by":"crossref","first-page":"24","DOI":"10.1016\/j.addr.2010.05.006","article-title":"Superparamagnetic iron oxide nanoparticles (SPIONs): Development, surface modification and applications in chemotherapy","volume":"63","author":"Mahmoudi","year":"2011","journal-title":"Adv. Drug Deliv. Rev."},{"key":"10.1016\/j.jconrel.2022.09.065_bb0890","doi-asserted-by":"crossref","first-page":"422","DOI":"10.1016\/j.actbio.2019.01.064","article-title":"Brain and bone cancer targeting by a ferrofluid composed of superparamagnetic iron-oxide\/silica\/carbon nanoparticles (earthicles)","volume":"88","author":"Wu","year":"2019","journal-title":"Acta Biomater."},{"key":"10.1016\/j.jconrel.2022.09.065_bb0895","doi-asserted-by":"crossref","first-page":"2613","DOI":"10.3390\/ijms19092613","article-title":"Evaluation of toxicity and neural uptake in vitro and in vivo of superparamagnetic iron oxide nanoparticles","volume":"19","author":"Khalid","year":"2018","journal-title":"Int. J. Mol. Sci."},{"key":"10.1016\/j.jconrel.2022.09.065_bb0900","doi-asserted-by":"crossref","first-page":"15","DOI":"10.1177\/0885328220975570","article-title":"Citric acid coated ultrasmall superparamagnetic iron oxide nanoparticles conjugated with lactoferrin for targeted negative MR imaging of glioma","volume":"36","author":"Xiao","year":"2021","journal-title":"J. Biomater. Appl."},{"key":"10.1016\/j.jconrel.2022.09.065_bb0905","doi-asserted-by":"crossref","first-page":"101","DOI":"10.2147\/IJN.S173954","article-title":"Doxorubicin and indocyanine green loaded superparamagnetic iron oxide nanoparticles with PEGylated phospholipid coating for magnetic resonance with fluorescence imaging and chemotherapy of glioma","volume":"14","author":"Shen","year":"2019","journal-title":"Int. J. 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Fibre Toxicol."},{"key":"10.1016\/j.jconrel.2022.09.065_bb0945","doi-asserted-by":"crossref","first-page":"16","DOI":"10.1016\/j.ymeth.2021.04.018","article-title":"Magnetite nanoparticles: Synthesis methods-A comparative review","volume":"199","author":"Niculescu","year":"2022","journal-title":"Methods"},{"key":"10.1016\/j.jconrel.2022.09.065_bb0950","doi-asserted-by":"crossref","first-page":"1841","DOI":"10.1038\/nm.2995","article-title":"Multifunctional in vivo vascular imaging using near-infrared II fluorescence","volume":"18","author":"Hong","year":"2012","journal-title":"Nat. Med."},{"key":"10.1016\/j.jconrel.2022.09.065_bb0955","doi-asserted-by":"crossref","first-page":"1703451","DOI":"10.1002\/adfm.201703451","article-title":"Ultrastable and biocompatible NIR-II quantum dots for functional bioimaging","volume":"28","author":"Zebibula","year":"2018","journal-title":"Adv. Funct. Mater."},{"key":"10.1016\/j.jconrel.2022.09.065_bb0960","doi-asserted-by":"crossref","first-page":"12830","DOI":"10.1021\/acsnano.9b05038","article-title":"Molecular targeting nanoprobes with non-overlap emission in the second near-infrared window for in vivo two-color colocalization of immune cells","volume":"13","author":"Yu","year":"2019","journal-title":"ACS Nano"},{"key":"10.1016\/j.jconrel.2022.09.065_bb0965","doi-asserted-by":"crossref","first-page":"2001003","DOI":"10.1002\/smll.202001003","article-title":"Controlled synthesis of Ag2Te@Ag2S core\u2013shell quantum dots with enhanced and tunable fluorescence in the second near-infrared window","volume":"16","author":"Zhang","year":"2020","journal-title":"Small"},{"key":"10.1016\/j.jconrel.2022.09.065_bb0970","doi-asserted-by":"crossref","first-page":"5678","DOI":"10.1039\/C9NR10918H","article-title":"Facile synthesis of noncytotoxic PEGylated dendrimer encapsulated silver sulfide quantum dots for NIR-II biological imaging","volume":"12","author":"Awasthi","year":"2020","journal-title":"Nanoscale"},{"key":"10.1016\/j.jconrel.2022.09.065_bb0975","doi-asserted-by":"crossref","first-page":"1907365","DOI":"10.1002\/adma.201907365","article-title":"Multiplexed NIR-II probes for lymph node-invaded cancer detection and imaging-guided surgery","volume":"32","author":"Tian","year":"2020","journal-title":"Adv. Mater."},{"key":"10.1016\/j.jconrel.2022.09.065_bb0980","doi-asserted-by":"crossref","first-page":"2199","DOI":"10.1038\/ncomms3199","article-title":"Rare-earth-doped biological composites as in vivo shortwave infrared reporters","volume":"4","author":"Naczynski","year":"2013","journal-title":"Nat. Commun."},{"key":"10.1016\/j.jconrel.2022.09.065_bb0985","doi-asserted-by":"crossref","first-page":"4241","DOI":"10.1021\/acsapm.0c00679","article-title":"Recent advances in conjugated polymer nanoparticles for NIR-II imaging and therapy","volume":"2","author":"Gao","year":"2020","journal-title":"ACS Appl. Polym. Mater."},{"key":"10.1016\/j.jconrel.2022.09.065_bb0990","doi-asserted-by":"crossref","first-page":"6590","DOI":"10.1073\/pnas.1806153115","article-title":"Bright quantum dots emitting at \u223c1,600 nm in the NIR-IIb window for deep tissue fluorescence imaging","volume":"115","author":"Zhang","year":"2018","journal-title":"Proc. Natl. Acad. Sci. U. S. A."},{"key":"10.1016\/j.jconrel.2022.09.065_bb0995","doi-asserted-by":"crossref","first-page":"2361","DOI":"10.1126\/science.1078727","article-title":"Structure-assigned optical spectra of single-walled carbon nanotubes","volume":"298","author":"Bachilo Sergei","year":"2002","journal-title":"Science"},{"key":"10.1016\/j.jconrel.2022.09.065_bb1000","doi-asserted-by":"crossref","first-page":"443","DOI":"10.1038\/nnano.2010.68","article-title":"Advanced sorting of single-walled carbon nanotubes by nonlinear density-gradient ultracentrifugation","volume":"5","author":"Ghosh","year":"2010","journal-title":"Nat. Nanotechnol."},{"key":"10.1016\/j.jconrel.2022.09.065_bb1005","doi-asserted-by":"crossref","first-page":"309","DOI":"10.1038\/ncomms1313","article-title":"Large-scale single-chirality separation of single-wall carbon nanotubes by simple gel chromatography","volume":"2","author":"Liu","year":"2011","journal-title":"Nat. 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