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Soc."},{"key":"10.1016\/j.jconrel.2023.11.014_bb0325","doi-asserted-by":"crossref","first-page":"444","DOI":"10.1039\/D0NR07484E","article-title":"Advanced nitric oxide donors: chemical structure of NO drugs, NO nanomedicines and biomedical applications","volume":"13","author":"Yang","year":"2021","journal-title":"Nanoscale."},{"key":"10.1016\/j.jconrel.2023.11.014_bb0330","doi-asserted-by":"crossref","first-page":"8103","DOI":"10.1039\/C8SC03386B","article-title":"A light-induced nitric oxide controllable release nano-platform based on diketopyrrolopyrrole derivatives for pH-responsive photodynamic\/photothermal synergistic cancer therapy","volume":"9","author":"Wang","year":"2018","journal-title":"Chem. Sci."},{"key":"10.1016\/j.jconrel.2023.11.014_bb0335","doi-asserted-by":"crossref","first-page":"1914","DOI":"10.1002\/1521-3773(20020603)41:11<1914::AID-ANIE1914>3.0.CO;2-J","article-title":"Light-controlled nitric oxide generation from a novel self-assembled monolayer on a gold surface","volume":"41","author":"Sortino","year":"2002","journal-title":"Angew. Chem. Int. Ed."},{"key":"10.1016\/j.jconrel.2023.11.014_bb0340","doi-asserted-by":"crossref","first-page":"1149","DOI":"10.1016\/0006-2952(92)90379-W","article-title":"Thiol-mediated generation of nitric oxide accounts for the vasodilator action of furoxans","volume":"44","author":"Feelisch","year":"1992","journal-title":"Biochem. 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Biol."},{"key":"10.1016\/j.jconrel.2023.11.014_bb0355","doi-asserted-by":"crossref","first-page":"716","DOI":"10.1093\/jn\/136.3.v","article-title":"Significance of garlic and its constituents in cancer and cardiovascular disease","volume":"136","author":"Rivlin","year":"2006","journal-title":"J. Nutr."},{"key":"10.1016\/j.jconrel.2023.11.014_bb0360","doi-asserted-by":"crossref","first-page":"4196","DOI":"10.1021\/acs.orglett.5b01962","article-title":"Diallyl Trisulfide is a fast H2S donor, but Diallyl disulfide is a slow one: the reaction pathways and intermediates of glutathione with Polysulfides","volume":"17","author":"Liang","year":"2015","journal-title":"Org. Lett."},{"key":"10.1016\/j.jconrel.2023.11.014_bb0365","doi-asserted-by":"crossref","first-page":"17977","DOI":"10.1073\/pnas.0705710104","article-title":"Hydrogen sulfide mediates the vasoactivity of garlic","volume":"104","author":"Benavides","year":"2007","journal-title":"Proc. Natl. Acad. Sci. U. S. A."},{"key":"10.1016\/j.jconrel.2023.11.014_bb0370","doi-asserted-by":"crossref","first-page":"3595","DOI":"10.3390\/molecules26123595","article-title":"Synthesis and reactivity of 3 H -1,2-dithiole-3-thiones","volume":"26","author":"Rakitin","year":"2021","journal-title":"Molecules."},{"key":"10.1016\/j.jconrel.2023.11.014_bb0375","doi-asserted-by":"crossref","first-page":"6275","DOI":"10.1021\/jm901638j","article-title":"Synthesis and biological effects of hydrogen sulfide (H2S): development of H2S-releasing drugs as pharmaceuticals","volume":"53","author":"Caliendo","year":"2010","journal-title":"J. Med. Chem."},{"key":"10.1016\/j.jconrel.2023.11.014_bb0380","doi-asserted-by":"crossref","first-page":"1290","DOI":"10.1021\/bc500150s","article-title":"Design and synthesis of polymeric hydrogen sulfide donors","volume":"25","author":"Hasegawa","year":"2014","journal-title":"Bioconjug. Chem."},{"key":"10.1016\/j.jconrel.2023.11.014_bb0385","doi-asserted-by":"crossref","first-page":"1061","DOI":"10.1124\/dmd.119.087205","article-title":"Mechanism of H 2 S formation from the metabolism of Anetholedithiolethione and Anetholedithiolone by rat liver Microsomes","volume":"47","author":"Dulac","year":"2019","journal-title":"Drug Metab. Dispos."},{"key":"10.1016\/j.jconrel.2023.11.014_bb0390","doi-asserted-by":"crossref","first-page":"2351","DOI":"10.1161\/CIRCULATIONAHA.107.753467","article-title":"Characterization of a novel, water-soluble hydrogen sulfide-releasing molecule (GYY4137): new insights into the biology of hydrogen sulfide","volume":"117","author":"Li","year":"2008","journal-title":"Circulation."},{"key":"10.1016\/j.jconrel.2023.11.014_bb0395","doi-asserted-by":"crossref","first-page":"360","DOI":"10.1164\/rccm.200907-1145OC","article-title":"Hydrogen sulfide improves neutrophil migration and survival in sepsis via K+ATP channel activation","volume":"182","author":"Spiller","year":"2010","journal-title":"Am. J. Respir. Crit. Care Med."},{"key":"10.1016\/j.jconrel.2023.11.014_bb0400","doi-asserted-by":"crossref","first-page":"904","DOI":"10.1021\/ml400239a","article-title":"Arylthioamides as H2S donors: l-cysteine-activated releasing properties and vascular effects in vitro and in vivo","volume":"4","author":"Martelli","year":"2013","journal-title":"ACS Med. Chem. Lett."},{"key":"10.1016\/j.jconrel.2023.11.014_bb0405","doi-asserted-by":"crossref","first-page":"1558","DOI":"10.1021\/ol500385a","article-title":"S-aroylthiooximes: a facile route to hydrogen sulfide releasing compounds with structure-dependent release kinetics","volume":"16","author":"Foster","year":"2014","journal-title":"Org. Lett."},{"key":"10.1016\/j.jconrel.2023.11.014_bb0410","doi-asserted-by":"crossref","first-page":"1300","DOI":"10.1021\/acs.molpharmaceut.6b01117","article-title":"H2S-releasing polymer micelles for studying selective cell toxicity","volume":"14","author":"Foster","year":"2017","journal-title":"Mol. Pharm."},{"key":"10.1016\/j.jconrel.2023.11.014_bb0415","doi-asserted-by":"crossref","first-page":"2786","DOI":"10.1021\/ol401118k","article-title":"Light-induced hydrogen sulfide release from \u201ccaged\u201d gem-dithiols","volume":"15","author":"Devarie-Baez","year":"2013","journal-title":"Org. Lett."},{"key":"10.1016\/j.jconrel.2023.11.014_bb0420","doi-asserted-by":"crossref","first-page":"331","DOI":"10.1039\/a827331z","article-title":"NO problem for nitroglycerin: organic nitrate chemistry and therapy","volume":"27","author":"Thatcher","year":"1998","journal-title":"Chem. Soc. Rev."},{"key":"10.1016\/j.jconrel.2023.11.014_bb0425","doi-asserted-by":"crossref","first-page":"2099","DOI":"10.1002\/pola.27221","article-title":"Organic nitrate functional nanoparticles for the glutathione-triggered slow-release of nitric oxide","volume":"52","author":"Duong","year":"2014","journal-title":"J. Polym. Sci. Part A Polym. Chem."},{"key":"10.1016\/j.jconrel.2023.11.014_bb0430","series-title":"Nitric Oxide Donors: For Pharmaceutical and Biological Applications","author":"Wang","year":"2005"},{"key":"10.1016\/j.jconrel.2023.11.014_bb0435","doi-asserted-by":"crossref","first-page":"341","DOI":"10.1039\/C3TB21259A","article-title":"A platform for nitric oxide delivery","volume":"2","author":"Kim","year":"2014","journal-title":"J. Mater. Chem. B"},{"key":"10.1016\/j.jconrel.2023.11.014_bb0440","doi-asserted-by":"crossref","first-page":"1638","DOI":"10.1111\/bph.12688","article-title":"Novel lead structures and activation mechanisms for CO-releasing molecules (CORMs)","volume":"172","author":"Schatzschneider","year":"2015","journal-title":"Br. J. Pharmacol."},{"key":"10.1016\/j.jconrel.2023.11.014_bb0445","doi-asserted-by":"crossref","first-page":"e2","DOI":"10.1161\/01.RES.0000084381.86567.08","article-title":"Cardioprotective actions by a water-soluble carbon monoxide-releasing molecule","volume":"93","author":"Clark","year":"2003","journal-title":"Circ. Res."},{"key":"10.1016\/j.jconrel.2023.11.014_bb0450","doi-asserted-by":"crossref","first-page":"1500","DOI":"10.1039\/b613629j","article-title":"Metal carbonyls as pharmaceuticals? [Ru(CO)3Cl(glycinate)], a CO-releasing molecule with an extensive aqueous solution chemistry","author":"Johnson","year":"2007","journal-title":"Dalton Trans."},{"key":"10.1016\/j.jconrel.2023.11.014_bb0455","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1096\/fj.04-2169fje","article-title":"CORM-A1: a new pharmacologically active carbon monoxide-releasing molecule","volume":"19","author":"Motterlini","year":"2005","journal-title":"FASEB J."},{"key":"10.1016\/j.jconrel.2023.11.014_bb0460","doi-asserted-by":"crossref","first-page":"1377","DOI":"10.1021\/acs.accounts.8b00019","article-title":"Strategies toward organic carbon monoxide prodrugs","volume":"51","author":"Ji","year":"2018","journal-title":"Acc. Chem. Res."},{"key":"10.1016\/j.jconrel.2023.11.014_bb0465","doi-asserted-by":"crossref","first-page":"4552","DOI":"10.1021\/ol4021089","article-title":"Fluorescein analogue xanthene-9-carboxylic acid: a transition-metal-free CO releasing molecule activated by green light","volume":"15","author":"Antony","year":"2013","journal-title":"Org. Lett."},{"key":"10.1016\/j.jconrel.2023.11.014_bb0470","doi-asserted-by":"crossref","first-page":"6671","DOI":"10.1039\/c3ob41385c","article-title":"Visible-light activatable organic CO-releasing molecules (PhotoCORMs) that simultaneously generate fluorophores","volume":"11","author":"Peng","year":"2013","journal-title":"Org. Biomol. Chem."},{"key":"10.1016\/j.jconrel.2023.11.014_bb0475","doi-asserted-by":"crossref","first-page":"126","DOI":"10.1021\/jacs.5b10800","article-title":"Transition-metal-free CO-releasing BODIPY derivatives activatable by visible to NIR light as promising bioactive molecules","volume":"138","author":"Palao","year":"2016","journal-title":"J. Am. Chem. Soc."},{"key":"10.1016\/j.jconrel.2023.11.014_bb0480","doi-asserted-by":"crossref","first-page":"590","DOI":"10.1002\/open.201500167","article-title":"A structurally-tunable 3-Hydroxyflavone motif for visible light-induced carbon monoxide-releasing molecules (CORMs)","volume":"4","author":"Anderson","year":"2015","journal-title":"ChemistryOpen."},{"key":"10.1016\/j.jconrel.2023.11.014_bb0485","doi-asserted-by":"crossref","first-page":"787","DOI":"10.1038\/s41557-018-0055-2","article-title":"Enrichment-triggered prodrug activation demonstrated through mitochondria-targeted delivery of doxorubicin and carbon monoxide","volume":"10","author":"Zheng","year":"2018","journal-title":"Nat. Chem."},{"key":"10.1016\/j.jconrel.2023.11.014_bb0490","doi-asserted-by":"crossref","first-page":"1252","DOI":"10.3390\/molecules24071252","article-title":"3-Hydroxyflavones and 3-hydroxy-4-oxoquinolines as carbon monoxide-releasing molecules","volume":"24","author":"Soboleva","year":"2019","journal-title":"Molecules."},{"key":"10.1016\/j.jconrel.2023.11.014_bb0495","doi-asserted-by":"crossref","first-page":"2611","DOI":"10.1021\/acs.jmedchem.6b01153","article-title":"Carbon monoxide and its controlled release: therapeutic application, detection, and development of carbon monoxide releasing molecules (CORMs)","volume":"61","author":"Ling","year":"2018","journal-title":"J. Med. Chem."},{"key":"10.1016\/j.jconrel.2023.11.014_bb0500","doi-asserted-by":"crossref","first-page":"1142","DOI":"10.1042\/BST0351142","article-title":"Carbon monoxide-releasing molecules (CO-RMs): vasodilatory, anti-ischaemic and anti-inflammatory activities","volume":"35","author":"Motterlini","year":"2007","journal-title":"Biochem. Soc. Trans."},{"key":"10.1016\/j.jconrel.2023.11.014_bb0505","doi-asserted-by":"crossref","first-page":"199","DOI":"10.1016\/j.ejmech.2013.12.041","article-title":"Syntheses and evaluation of drug-like properties of CO-releasing molecules containing ruthenium and group 6 metal","volume":"74","author":"Wang","year":"2014","journal-title":"Eur. J. Med. Chem."},{"key":"10.1016\/j.jconrel.2023.11.014_bb0510","doi-asserted-by":"crossref","first-page":"3135","DOI":"10.1021\/ja003932b","article-title":"Synthesis and properties of boranocarbonate: a convenient in situ CO source for the aqueous preparation of [99mTc(OH2)3(CO)3]+","volume":"123","author":"Alberto","year":"2001","journal-title":"J. Am. Chem. Soc."},{"key":"10.1016\/j.jconrel.2023.11.014_bb0515","doi-asserted-by":"crossref","first-page":"9435","DOI":"10.1021\/jacs.7b04077","article-title":"Sense and release: a thiol-responsive Flavonol-based Photonically driven carbon monoxide-releasing molecule that operates via a multiple-input and logic gate","volume":"139","author":"Lazarus","year":"2017","journal-title":"J. Am. Chem. Soc."},{"key":"10.1016\/j.jconrel.2023.11.014_bb0520","doi-asserted-by":"crossref","first-page":"2220","DOI":"10.1021\/acschembio.8b00387","article-title":"Mitochondrial-localized versus cytosolic intracellular CO-releasing organic PhotoCORMs: evaluation of CO effects using bioenergetics","volume":"13","author":"Lazarus","year":"2018","journal-title":"ACS Chem. Biol."},{"key":"10.1016\/j.jconrel.2023.11.014_bb0525","doi-asserted-by":"crossref","first-page":"9721","DOI":"10.1021\/jacs.8b06011","article-title":"Visible-light-activated quinolone carbon-monoxide-releasing molecule: prodrug and albumin-assisted delivery enables anticancer and potent anti-inflammatory effects","volume":"140","author":"Popova","year":"2018","journal-title":"J. Am. Chem. Soc."},{"key":"10.1016\/j.jconrel.2023.11.014_bb0530","doi-asserted-by":"crossref","DOI":"10.1016\/j.addr.2021.114005","article-title":"Engineering macromolecular nanocarriers for local delivery of gaseous signaling molecules","volume":"179","author":"Hu","year":"2021","journal-title":"Adv. Drug Deliv. Rev."},{"key":"10.1016\/j.jconrel.2023.11.014_bb0535","doi-asserted-by":"crossref","first-page":"157","DOI":"10.1016\/j.jconrel.2018.04.025","article-title":"Use of gasotransmitters for the controlled release of polymer-based nitric oxide carriers in medical applications","volume":"279","author":"Yang","year":"2018","journal-title":"J. Control. Release"},{"key":"10.1016\/j.jconrel.2023.11.014_bb0540","doi-asserted-by":"crossref","first-page":"5626","DOI":"10.1523\/JNEUROSCI.3659-12.2013","article-title":"Nitric oxide synthesis and cGMP production is important for neurite growth and synapse remodeling after Axotomy","volume":"33","author":"Cooke","year":"2013","journal-title":"J. Neurosci."},{"key":"10.1016\/j.jconrel.2023.11.014_bb0545","doi-asserted-by":"crossref","first-page":"107","DOI":"10.1006\/niox.1997.0118","article-title":"Nitric oxide: cytotoxicity versus Cytoprotection\u2014 how, why, when, and where?","volume":"1","author":"Kr\u00f6ncke","year":"1997","journal-title":"Nitric Oxide"},{"key":"10.1016\/j.jconrel.2023.11.014_bb0550","doi-asserted-by":"crossref","first-page":"713","DOI":"10.1021\/jm701491k","article-title":"Synthesis and biological evaluation of NO-donor-tacrine hybrids as hepatoprotective anti-Alzheimer drug candidates","volume":"51","author":"Fang","year":"2008","journal-title":"J. Med. Chem."},{"key":"10.1016\/j.jconrel.2023.11.014_bb0555","doi-asserted-by":"crossref","first-page":"7666","DOI":"10.1021\/jm801131a","article-title":"NO-donating tacrine hybrid compounds improve scopolamine-induced cognition impairment and show less hepatotoxicity","volume":"51","author":"Fang","year":"2008","journal-title":"J. Med. Chem."},{"key":"10.1016\/j.jconrel.2023.11.014_bb0560","doi-asserted-by":"crossref","first-page":"4309","DOI":"10.1021\/jm300106z","article-title":"Tacrine-ferulic acid-nitric oxide (NO) donor trihybrids as potent, multifunctional acetyl- and butyrylcholinesterase inhibitors","volume":"55","author":"Chen","year":"2012","journal-title":"J. Med. Chem."},{"key":"10.1016\/j.jconrel.2023.11.014_bb0565","doi-asserted-by":"crossref","first-page":"602","DOI":"10.1002\/ana.1249","article-title":"A nitric oxide donor induces neurogenesis and reduces functional deficits after stroke in rats","volume":"50","author":"Zhang","year":"2001","journal-title":"Ann. Neurol."},{"key":"10.1016\/j.jconrel.2023.11.014_bb0570","doi-asserted-by":"crossref","first-page":"351","DOI":"10.3171\/jns.2003.99.2.0351","article-title":"Upregulation of neurogenesis and reduction in functional deficits following administration of DETA\/NONOate, a nitric oxide donor, after traumatic brain injury in rats","volume":"99","author":"Lu","year":"2003","journal-title":"J. Neurosurg."},{"key":"10.1016\/j.jconrel.2023.11.014_bb0575","doi-asserted-by":"crossref","first-page":"2043","DOI":"10.4103\/1673-5374.335160","article-title":"Delivery of nitric oxide-releasing silica nanoparticles for in vivo revascularization and functional recovery after acute peripheral nerve crush injury","volume":"17","author":"Il Lee","year":"2022","journal-title":"Neural Regen. Res."},{"key":"10.1016\/j.jconrel.2023.11.014_bb0580","first-page":"998","article-title":"Endogenous conjugation of biomimetic Dinitrosyl Iron complex with protein vehicles for Oral delivery of nitric oxide to brain and activation of hippocampal neurogenesis","volume":"1","author":"Wu","year":"2021","journal-title":"J. Am. Chem. Soc. Au."},{"key":"10.1016\/j.jconrel.2023.11.014_bb0585","doi-asserted-by":"crossref","first-page":"6171","DOI":"10.1039\/C6SC05017D","article-title":"Self-assembling soft structures for intracellular NO release and promotion of neurite outgrowth","volume":"8","author":"Pal","year":"2017","journal-title":"Chem. Sci."},{"key":"10.1016\/j.jconrel.2023.11.014_bb0590","doi-asserted-by":"crossref","first-page":"eabc3513","DOI":"10.1126\/sciadv.abc3513","article-title":"Near-infrared light-triggered NO release for spinal cord injury repair","volume":"6","author":"Jiang","year":"2020","journal-title":"Sci. Adv."},{"key":"10.1016\/j.jconrel.2023.11.014_bb0595","doi-asserted-by":"crossref","first-page":"13853","DOI":"10.1021\/acs.jmedchem.1c01240","article-title":"Blood-brain barrier permeable and NO-releasing multifunctional nanoparticles for Alzheimer\u2019s disease treatment: targeting NO\/cGMP\/CREB signaling pathways","volume":"64","author":"Liu","year":"2021","journal-title":"J. Med. Chem."},{"key":"10.1016\/j.jconrel.2023.11.014_bb0600","doi-asserted-by":"crossref","first-page":"690","DOI":"10.1038\/s41565-020-0701-x","article-title":"In situ electrochemical generation of nitric oxide for neuronal modulation","volume":"15","author":"Park","year":"2020","journal-title":"Nat. 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Neurosci."},{"key":"10.1016\/j.jconrel.2023.11.014_bb0615","doi-asserted-by":"crossref","DOI":"10.1016\/j.bioadv.2022.212743","article-title":"Implantation of injectable SF hydrogel with sustained hydrogen sulfide delivery reduces neuronal pyroptosis and enhances functional recovery after severe intracerebral hemorrhage","volume":"135","author":"Zhang","year":"2022","journal-title":"Biomater. 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A."},{"key":"10.1016\/j.jconrel.2023.11.014_bb0630","doi-asserted-by":"crossref","first-page":"1152","DOI":"10.1016\/j.cmet.2019.10.007","article-title":"Selective Persulfide detection reveals evolutionarily conserved antiaging effects of S-Sulfhydration","volume":"30","author":"Zivanovic","year":"2019","journal-title":"Cell Metab."},{"key":"10.1016\/j.jconrel.2023.11.014_bb0635","doi-asserted-by":"crossref","first-page":"935","DOI":"10.1161\/CIRCULATIONAHA.120.051877","article-title":"Mapping the endothelial cell S-sulfhydrome highlights the crucial role of integrin sulfhydration in vascular function","volume":"143","author":"Bibli","year":"2021","journal-title":"Circulation"},{"key":"10.1016\/j.jconrel.2023.11.014_bb0640","doi-asserted-by":"crossref","first-page":"1375","DOI":"10.1007\/s11064-013-1034-z","article-title":"Slow regulated release of H 2 S inhibits oxidative stress induced cell death by influencing certain key signaling molecules","volume":"38","author":"Majid","year":"2013","journal-title":"Neurochem. 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