{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,11,2]],"date-time":"2026-11-02T22:01:46Z","timestamp":1793656906508,"version":"4.5.1"},"reference-count":47,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2024,8,1]],"date-time":"2024-08-01T00:00:00Z","timestamp":1722470400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2024,8,1]],"date-time":"2024-08-01T00:00:00Z","timestamp":1722470400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2024,6,20]],"date-time":"2024-06-20T00:00:00Z","timestamp":1718841600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/100010663","name":"European Research Council","doi-asserted-by":"publisher","award":["694968"],"award-info":[{"award-number":["694968"]}],"id":[{"id":"10.13039\/100010663","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001659","name":"Deutsche Forschungsgemeinschaft","doi-asserted-by":"publisher","award":["NT 3\/10\\u20131"],"award-info":[{"award-number":["NT 3\/10\\u20131"]}],"id":[{"id":"10.13039\/501100001659","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001659","name":"Deutsche Forschungsgemeinschaft","doi-asserted-by":"publisher","award":["CRC 1123 (Z1"],"award-info":[{"award-number":["CRC 1123 (Z1"]}],"id":[{"id":"10.13039\/501100001659","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100009318","name":"Helmholtz Association","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100009318","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100000781","name":"European Research Council","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100000781","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100007601","name":"Horizon 2020","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100007601","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100002347","name":"BMBF Bonn","doi-asserted-by":"publisher","award":["16GW0251K"],"award-info":[{"award-number":["16GW0251K"]}],"id":[{"id":"10.13039\/501100002347","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Journal of Controlled Release"],"published-print":{"date-parts":[[2024,8]]},"DOI":"10.1016\/j.jconrel.2024.06.037","type":"journal-article","created":{"date-parts":[[2024,6,27]],"date-time":"2024-06-27T19:32:16Z","timestamp":1719516736000},"page":"522-530","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":4,"special_numbering":"C","title":["Tuning the photophysical properties of cyanine by barbiturate functionalization and nanoformulation for efficient optoacoustics- guided phototherapy"],"prefix":"10.1016","volume":"372","author":[{"given":"Nian","family":"Liu","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Patrick","family":"O'Connor","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Vipul","family":"Gujrati","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Divyesh","family":"Shelar","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xiaopeng","family":"Ma","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pia","family":"Anzenhofer","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Uwe","family":"Klemm","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xinhui","family":"Su","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yuanhui","family":"Huang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Karin","family":"Kleigrewe","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Annette","family":"Feuchtinger","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Axel","family":"Walch","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michael","family":"Sattler","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Oliver","family":"Plettenburg","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Vasilis","family":"Ntziachristos","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"issue":"9","key":"10.1016\/j.jconrel.2024.06.037_bb0005","doi-asserted-by":"crossref","first-page":"2002115","DOI":"10.1002\/adhm.202002115","article-title":"Facile synthesis of a croconaine-based nanoformulation for OptA imaging and photothermal therapy","volume":"10","author":"Liu","year":"2021","journal-title":"Adv. Healthc. Mater."},{"issue":"7","key":"10.1016\/j.jconrel.2024.06.037_bb0010","doi-asserted-by":"crossref","first-page":"2053","DOI":"10.1039\/C8CS00618K","article-title":"Photothermal therapy and photoacoustic imaging via nanotheranostics in fighting cancer","volume":"48","author":"Liu","year":"2019","journal-title":"Chem. Soc. Rev."},{"issue":"1","key":"10.1016\/j.jconrel.2024.06.037_bb0015","doi-asserted-by":"crossref","first-page":"36","DOI":"10.1186\/s12645-023-00191-w","article-title":"Bacterial outer membrane vesicles as cationic dye carriers for OptAs-guided phototherapy of cancer","volume":"14","author":"Liu","year":"2023","journal-title":"Cancer Nanotechnol."},{"issue":"18","key":"10.1016\/j.jconrel.2024.06.037_bb0020","doi-asserted-by":"crossref","first-page":"3645","DOI":"10.1515\/nanoph-2023-0358","article-title":"Squaraine nanoparticles for OptA imaging-guided synergistic cancer phototherapy","volume":"12","author":"Chen","year":"2023","journal-title":"Nanophotonics"},{"issue":"3","key":"10.1016\/j.jconrel.2024.06.037_bb0025","first-page":"847","article-title":"Photothermal therapy","volume":"49","author":"Zhi","year":"2022","journal-title":"J. Control. Release"},{"issue":"21","key":"10.1016\/j.jconrel.2024.06.037_bb0030","doi-asserted-by":"crossref","first-page":"4637","DOI":"10.1515\/nanoph-2022-0469","article-title":"Multifunctional croconaine nanoparticles for efficient OptA imaging of deep tumors and photothermal therapy","volume":"11","author":"Liu","year":"2022","journal-title":"Nanophotonics"},{"key":"10.1016\/j.jconrel.2024.06.037_bb0035","doi-asserted-by":"crossref","DOI":"10.1016\/j.addr.2022.114506","article-title":"The sound of drug delivery: OptA imaging in pharmacology","volume":"189","author":"Liu","year":"2022","journal-title":"Adv. Drug Deliv. Rev."},{"issue":"13","key":"10.1016\/j.jconrel.2024.06.037_bb0040","doi-asserted-by":"crossref","first-page":"4152","DOI":"10.1007\/s00259-021-05207-4","article-title":"Multi-scale OptA molecular imaging of brain diseases","volume":"48","author":"Razansky","year":"2021","journal-title":"Eur. J. Nucl. Med. Mol. Imaging"},{"issue":"37","key":"10.1016\/j.jconrel.2024.06.037_bb0045","doi-asserted-by":"crossref","first-page":"2104650","DOI":"10.1002\/adfm.202104650","article-title":"Organic semiconducting macromolecular dyes for NIR-II photoacoustic imaging and Photothermal therapy","volume":"31","author":"Yin","year":"2021","journal-title":"Adv. Funct. Mater."},{"issue":"10","key":"10.1016\/j.jconrel.2024.06.037_bb0050","doi-asserted-by":"crossref","first-page":"1385","DOI":"10.1007\/s00109-021-02115-w","article-title":"In vivo optical molecular imaging of inflammation and immunity","volume":"99","author":"Liu","year":"2021","journal-title":"J. Mol. Med."},{"issue":"41","key":"10.1016\/j.jconrel.2024.06.037_bb0055","doi-asserted-by":"crossref","first-page":"22376","DOI":"10.1002\/anie.202107836","article-title":"A borondifluoride-complex-based photothermal agent with an 80% photothermal conversion efficiency for photothermal therapy in the NIR-II window","volume":"60","author":"Jiang","year":"2021","journal-title":"Angew. Chem. Int. Ed."},{"issue":"1","key":"10.1016\/j.jconrel.2024.06.037_bb0060","doi-asserted-by":"crossref","first-page":"348","DOI":"10.1186\/s12951-023-02111-x","article-title":"Near-infrared photodynamic and photothermal co-therapy based on organic small molecular dyes","volume":"21","author":"Guo","year":"2023","journal-title":"J. Nanobiotechnol."},{"key":"10.1016\/j.jconrel.2024.06.037_bb0065","doi-asserted-by":"crossref","first-page":"50","DOI":"10.1016\/j.jconrel.2020.11.046","article-title":"Self-assembled heptamethine cyanine dye dimer as a novel theranostic drug delivery carrier for effective image-guided chemo-photothermal cancer therapy","volume":"329","author":"Jeong","year":"2021","journal-title":"J. Control. Release"},{"issue":"14","key":"10.1016\/j.jconrel.2024.06.037_bb0070","doi-asserted-by":"crossref","DOI":"10.1002\/anie.202114722","article-title":"The chemistry of organic contrast agents in the NIR-II window","volume":"61","author":"Mu","year":"2022","journal-title":"Angew. Chem. Int. Ed."},{"key":"10.1016\/j.jconrel.2024.06.037_bb0075","doi-asserted-by":"crossref","first-page":"505","DOI":"10.1016\/j.dyepig.2017.06.029","article-title":"Fundamentals in the chemistry of cyanine dyes: a review","volume":"145","author":"Shindy","year":"2017","journal-title":"Dyes Pigments"},{"issue":"24","key":"10.1016\/j.jconrel.2024.06.037_bb0080","doi-asserted-by":"crossref","DOI":"10.1002\/adma.201900321","article-title":"Near-infrared-II molecular dyes for cancer imaging and surgery","volume":"31","author":"Zhu","year":"2019","journal-title":"Adv. Mater."},{"issue":"5","key":"10.1016\/j.jconrel.2024.06.037_bb0085","doi-asserted-by":"crossref","DOI":"10.1117\/1.JBO.21.5.050901","article-title":"Review on near-infrared heptamethine cyanine dyes as theranostic agents for tumor imaging, targeting, and photodynamic therapy","volume":"21","author":"Shi","year":"2016","journal-title":"J. Biomed. Opt."},{"issue":"17","key":"10.1016\/j.jconrel.2024.06.037_bb0090","doi-asserted-by":"crossref","first-page":"4465","DOI":"10.1073\/pnas.1718917115","article-title":"Shortwave infrared fluorescence imaging with the clinically approved near-infrared dye indocyanine green","volume":"115","author":"Carr","year":"2018","journal-title":"Proc. Natl. Acad. Sci."},{"key":"10.1016\/j.jconrel.2024.06.037_bb0095","doi-asserted-by":"crossref","DOI":"10.3389\/fchem.2021.707876","article-title":"Recent advances in cyanine-based phototherapy agents","volume":"9","author":"Bilici","year":"2021","journal-title":"Front. Chem."},{"issue":"6","key":"10.1016\/j.jconrel.2024.06.037_bb0100","doi-asserted-by":"crossref","first-page":"1175","DOI":"10.1111\/php.12967","article-title":"Molecular photoacoustic contrast agents: design principles & applications","volume":"94","author":"Borg","year":"2018","journal-title":"Photochem. Photobiol."},{"issue":"9","key":"10.1016\/j.jconrel.2024.06.037_bb0105","doi-asserted-by":"crossref","DOI":"10.1117\/1.JBO.20.9.096006","article-title":"Development of photostabilized asymmetrical cyanine dyes for in vivo photoacoustic imaging of tumors","volume":"20","author":"Onoe","year":"2015","journal-title":"J. Biomed. Opt."},{"key":"10.1016\/j.jconrel.2024.06.037_bb0110","doi-asserted-by":"crossref","DOI":"10.1016\/j.cej.2021.134355","article-title":"Anti-photobleaching cyanine-based nanoparticles with simultaneous PET and ACQ effects for improved tumor photothermal therapy","volume":"432","author":"Feng","year":"2022","journal-title":"Chem. Eng. J."},{"issue":"2","key":"10.1016\/j.jconrel.2024.06.037_bb0115","doi-asserted-by":"crossref","DOI":"10.1002\/adma.201906711","article-title":"Supramolecular nanodiscs self-assembled from non-ionic heptamethine cyanine for imaging-guided cancer photothermal therapy","volume":"32","author":"Mu","year":"2019","journal-title":"Adv. Mater."},{"key":"10.1016\/j.jconrel.2024.06.037_bb0120","doi-asserted-by":"crossref","DOI":"10.1016\/j.ccr.2021.214134","article-title":"Imaging strategies using cyanine probes and materials for biomedical visualization of live animals","volume":"447","author":"Fei","year":"2021","journal-title":"Coord. Chem. Rev."},{"issue":"21","key":"10.1016\/j.jconrel.2024.06.037_bb0125","doi-asserted-by":"crossref","first-page":"6025","DOI":"10.7150\/thno.26607","article-title":"Hypoxia-triggered single molecule probe for high-contrast NIR II\/PA tumor imaging and robust photothermal therapy","volume":"8","author":"Meng","year":"2018","journal-title":"Theranostics"},{"issue":"12","key":"10.1016\/j.jconrel.2024.06.037_bb0130","doi-asserted-by":"crossref","first-page":"6230","DOI":"10.1002\/anie.202008075","article-title":"Explorations into the effect of meso-substituents in tricarbocyanine dyes: a path to diverse biomolecular probes and materials","volume":"60","author":"Exner","year":"2021","journal-title":"Angew. Chem. Int. Ed."},{"issue":"4","key":"10.1016\/j.jconrel.2024.06.037_bb0135","doi-asserted-by":"crossref","first-page":"751","DOI":"10.1039\/C5TC03629A","article-title":"Enhanced AIE and different stimuli-responses in red fluorescent (1,3-dimethyl)barbituric acid-functionalized anthracenes","volume":"4","author":"Yin","year":"2016","journal-title":"J. Mater. Chem. C"},{"issue":"8","key":"10.1016\/j.jconrel.2024.06.037_bb0140","doi-asserted-by":"crossref","first-page":"2435","DOI":"10.1021\/acs.macromol.5b00046","article-title":"Effects of cross-conjugation on the optical absorption and frontier orbital levels of donor\u2013acceptor polymers","volume":"48","author":"van Pruissen","year":"2015","journal-title":"Macromolecules"},{"issue":"2","key":"10.1016\/j.jconrel.2024.06.037_bb0145","doi-asserted-by":"crossref","first-page":"123","DOI":"10.1016\/j.jphotochem.2004.08.010","article-title":"Evaluation of sensitizing ability of barbiturate-functionalized non-ionic cyanine dyes; application for photoinduced radical generation system initiated by near IR light","volume":"170","author":"Karatsu","year":"2005","journal-title":"J. Photochem. Photobiol. A Chem."},{"key":"10.1016\/j.jconrel.2024.06.037_bb0150","series-title":"Near infrared (NIR) laser markable compositions","author":"Lazreg","year":"2020"},{"issue":"1","key":"10.1016\/j.jconrel.2024.06.037_bb0155","doi-asserted-by":"crossref","first-page":"1506","DOI":"10.1016\/j.dyepig.2011.11.001","article-title":"A comparative study of symmetrical and unsymmetrical trimethine cyanine dyes bearing benzoxazolyl and benzothiazolyl groups","volume":"93","author":"Shi","year":"2012","journal-title":"Dyes Pigments"},{"issue":"4","key":"10.1016\/j.jconrel.2024.06.037_bb0160","doi-asserted-by":"crossref","first-page":"1015","DOI":"10.1248\/cpb.26.1015","article-title":"Radical methylation and radical hydroxymethylation of n-substituted quinoline derivatives","volume":"26","author":"Itokawa","year":"1978","journal-title":"Chem. Pharm. Bull."},{"issue":"31","key":"10.1016\/j.jconrel.2024.06.037_bb0165","doi-asserted-by":"crossref","first-page":"1700487","DOI":"10.1002\/adma.201700487","article-title":"Ultrastable near-infrared conjugated-polymer nanoparticles for dually photoactive tumor inhibition","volume":"29","author":"Yang","year":"2017","journal-title":"Adv. Mater."},{"issue":"3\u20134","key":"10.1016\/j.jconrel.2024.06.037_bb0170","doi-asserted-by":"crossref","first-page":"372","DOI":"10.1016\/S0009-2614(03)00608-0","article-title":"Fluorescence efficiency of four infrared polymethine dyes","volume":"373","author":"Casalboni","year":"2003","journal-title":"Chem. Phys. Lett."},{"issue":"15","key":"10.1016\/j.jconrel.2024.06.037_bb0175","doi-asserted-by":"crossref","first-page":"10717","DOI":"10.1021\/acs.analchem.0c01902","article-title":"Challenging a preconception: OptA spectrum differs from the optical absorption spectrum of proteins and dyes for molecular imaging","volume":"92","author":"Fuenzalida Werner","year":"2020","journal-title":"Anal. Chem."},{"issue":"5","key":"10.1016\/j.jconrel.2024.06.037_bb0180","doi-asserted-by":"crossref","first-page":"2229","DOI":"10.1364\/BOE.9.002229","article-title":"Performance of OptA and fluorescence imaging in detecting deep-seated fluorescent agents","volume":"9","author":"Chen","year":"2018","journal-title":"Biomed. Opt. Express"},{"issue":"9","key":"10.1016\/j.jconrel.2024.06.037_bb0185","doi-asserted-by":"crossref","first-page":"3636","DOI":"10.1021\/jp064341w","article-title":"Microscale heat transfer transduced by surface plasmon resonant gold nanoparticles","volume":"111","author":"Roper","year":"2007","journal-title":"J. Phys. Chem. C"},{"key":"10.1016\/j.jconrel.2024.06.037_bb0190","doi-asserted-by":"crossref","DOI":"10.1016\/j.pacs.2021.100263","article-title":"Croconaine-based nanoparticles enable efficient OptA imaging of murine brain tumors","volume":"22","author":"Liu","year":"2021","journal-title":"Photoacoustics"},{"issue":"28","key":"10.1016\/j.jconrel.2024.06.037_bb0195","doi-asserted-by":"crossref","first-page":"11440","DOI":"10.1002\/anie.202004413","article-title":"NIR-sensitized activated photoreaction between cyanines and oxime esters: free-radical photopolymerization","volume":"59","author":"Pang","year":"2020","journal-title":"Angew. Chem. Int. Ed."},{"issue":"26","key":"10.1016\/j.jconrel.2024.06.037_bb0200","doi-asserted-by":"crossref","first-page":"7898","DOI":"10.1002\/anie.201802964","article-title":"Near-infrared sensitized photoinduced atom-transfer radical polymerization (ATRP) with a copper(II) catalyst concentration in the ppm range","volume":"57","author":"K\u00fctahya","year":"2018","journal-title":"Angew. Chem. Int. Ed."},{"key":"10.1016\/j.jconrel.2024.06.037_bb0205","series-title":"Gaussian 16 Revision C.01","author":"Frisch","year":"2016"},{"issue":"1","key":"10.1016\/j.jconrel.2024.06.037_bb0210","doi-asserted-by":"crossref","first-page":"163","DOI":"10.2174\/187407070190130163","article-title":"Intralipid-based phantoms for the development of new optical diagnostic techniques","volume":"13","author":"Lepore","year":"2019","journal-title":"Open Biotechnol. J."},{"issue":"2","key":"10.1016\/j.jconrel.2024.06.037_bb0215","doi-asserted-by":"crossref","DOI":"10.1088\/1054-660X\/25\/2\/025605","article-title":"Optical properties measurement of highly diffusive tissue phantoms for biomedical applications","volume":"25","author":"Rehman","year":"2015","journal-title":"Laser Phys."},{"issue":"1","key":"10.1016\/j.jconrel.2024.06.037_bb0220","doi-asserted-by":"crossref","first-page":"1114","DOI":"10.1038\/s41467-019-09034-y","article-title":"Bioengineered bacterial vesicles as biological nano-heaters for OptA imaging","volume":"10","author":"Gujrati","year":"2019","journal-title":"Nat. Commun."},{"issue":"10","key":"10.1016\/j.jconrel.2024.06.037_bb0225","doi-asserted-by":"crossref","first-page":"12332","DOI":"10.1021\/acsami.4c02254","article-title":"Chalcogen atom-modulated croconaine for efficient NIR-II photothermal theranostics","volume":"16","author":"Chen","year":"2024","journal-title":"ACS Appl. Mater. Interfaces"},{"key":"10.1016\/j.jconrel.2024.06.037_bb0230","doi-asserted-by":"crossref","DOI":"10.1016\/j.snb.2024.135535","article-title":"Synchronously manipulating absorption and nonradiative transition of croconaine via donor engineering for efficient NIR-II photothermal theranostics","volume":"408","author":"Li","year":"2024","journal-title":"Sensors Actuators B Chem."},{"key":"10.1016\/j.jconrel.2024.06.037_bb0235","doi-asserted-by":"crossref","DOI":"10.1002\/smll.202002672","article-title":"Single-photomolecular nanotheranostics for synergetic near-infrared fluorescence and photoacoustic imaging-guided highly effective photothermal ablation","volume":"16","author":"Xiao","year":"2020","journal-title":"Small"}],"container-title":["Journal of Controlled Release"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0168365924003869?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0168365924003869?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2024,10,6]],"date-time":"2024-10-06T17:52:22Z","timestamp":1728237142000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0168365924003869"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,8]]},"references-count":47,"alternative-id":["S0168365924003869"],"URL":"https:\/\/doi.org\/10.1016\/j.jconrel.2024.06.037","relation":{},"ISSN":["0168-3659"],"issn-type":[{"value":"0168-3659","type":"print"}],"subject":[],"published":{"date-parts":[[2024,8]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Tuning the photophysical properties of cyanine by barbiturate functionalization and nanoformulation for efficient optoacoustics- guided phototherapy","name":"articletitle","label":"Article Title"},{"value":"Journal of Controlled Release","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.jconrel.2024.06.037","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2024 The Authors. Published by Elsevier B.V.","name":"copyright","label":"Copyright"}]}}