{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,18]],"date-time":"2026-09-18T18:21:25Z","timestamp":1789755685236,"version":"4.0.1"},"reference-count":57,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2025,3,1]],"date-time":"2025-03-01T00:00:00Z","timestamp":1740787200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2025,3,1]],"date-time":"2025-03-01T00:00:00Z","timestamp":1740787200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2025,6,2]],"date-time":"2025-06-02T00:00:00Z","timestamp":1748822400000},"content-version":"vor","delay-in-days":93,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100004837","name":"Ministerio de Ciencia e Innovaci\u00f3n","doi-asserted-by":"publisher","award":["PID2020-119949RB-I00"],"award-info":[{"award-number":["PID2020-119949RB-I00"]}],"id":[{"id":"10.13039\/501100004837","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100004837","name":"Ministerio de Ciencia e Innovaci\u00f3n","doi-asserted-by":"publisher","award":["PID2023-152689OB-I00"],"award-info":[{"award-number":["PID2023-152689OB-I00"]}],"id":[{"id":"10.13039\/501100004837","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100004837","name":"Ministerio de Ciencia e Innovaci\u00f3n","doi-asserted-by":"publisher","award":["PID2022-1381850B-I00"],"award-info":[{"award-number":["PID2022-1381850B-I00"]}],"id":[{"id":"10.13039\/501100004837","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100004837","name":"Ministerio de Ciencia e Innovaci\u00f3n","doi-asserted-by":"publisher","award":["RTI2018-098432-B-100"],"award-info":[{"award-number":["RTI2018-098432-B-100"]}],"id":[{"id":"10.13039\/501100004837","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100003339","name":"Consejo Superior de Investigaciones Cient\u00edficas","doi-asserted-by":"publisher","award":["CSIC-COV19-047"],"award-info":[{"award-number":["CSIC-COV19-047"]}],"id":[{"id":"10.13039\/501100003339","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100016970","name":"Consejer\u00eda de Econom\u00eda, Conocimiento, Empresas y Universidad, Junta de Andaluc\u00eda","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100016970","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100004895","name":"European Social Fund Plus","doi-asserted-by":"publisher","award":["POSTDOC_21_00594"],"award-info":[{"award-number":["POSTDOC_21_00594"]}],"id":[{"id":"10.13039\/501100004895","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100002924","name":"Federaci\u00f3n Espa\u00f1ola de Enfermedades Raras","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100002924","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100008530","name":"European Regional Development Fund","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100008530","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100011011","name":"Junta de Andaluc\u00eda","doi-asserted-by":"publisher","award":["FQM-313"],"award-info":[{"award-number":["FQM-313"]}],"id":[{"id":"10.13039\/501100011011","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100011011","name":"Junta de Andaluc\u00eda","doi-asserted-by":"publisher","award":["21-20073"],"award-info":[{"award-number":["21-20073"]}],"id":[{"id":"10.13039\/501100011011","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100011011","name":"Junta de Andaluc\u00eda","doi-asserted-by":"publisher","award":["CA-18132"],"award-info":[{"award-number":["CA-18132"]}],"id":[{"id":"10.13039\/501100011011","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Journal of Controlled Release"],"published-print":{"date-parts":[[2025,3]]},"DOI":"10.1016\/j.jconrel.2025.01.062","type":"journal-article","created":{"date-parts":[[2025,1,30]],"date-time":"2025-01-30T18:43:21Z","timestamp":1738262601000},"page":"890-905","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":8,"special_numbering":"C","title":["PSMA-targeted delivery of docetaxel in prostate cancer using small-sized PDA-based micellar nanovectors"],"prefix":"10.1016","volume":"379","author":[{"given":"Cristian","family":"Rosales-Barrios","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zaira I.","family":"Gonz\u00e1lez-S\u00e1nchez","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alessio","family":"Zuliani","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Juan M.","family":"Jim\u00e9nez-Vacas","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Raul M.","family":"Luque","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"David","family":"Pozo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Noureddine","family":"Khiar","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.jconrel.2025.01.062_bb0005","doi-asserted-by":"crossref","first-page":"43","DOI":"10.1007\/s40005-017-0370-4","article-title":"Nanomedicines: current status and future perspectives in aspect of drug delivery and pharmacokinetics","volume":"48","author":"Choi","year":"2018","journal-title":"J. Pharm. Investig."},{"key":"10.1016\/j.jconrel.2025.01.062_bb0010","doi-asserted-by":"crossref","first-page":"218","DOI":"10.1016\/j.ctrv.2016.09.017","article-title":"Early use of chemotherapy in metastatic prostate cancer","volume":"55","author":"Markowski","year":"2017","journal-title":"Cancer Treat. Rev."},{"key":"10.1016\/j.jconrel.2025.01.062_bb0015","doi-asserted-by":"crossref","first-page":"17","DOI":"10.1016\/j.addr.2018.07.007","article-title":"Tumor targeting via EPR: strategies to enhance patient responses","volume":"130","author":"Golombek","year":"2018","journal-title":"Adv. Drug Deliv. Rev."},{"key":"10.1016\/j.jconrel.2025.01.062_bb0020","doi-asserted-by":"crossref","first-page":"71","DOI":"10.1016\/j.addr.2012.10.002","article-title":"The EPR effect for macromolecular drug delivery to solid tumors: improvement of tumor uptake, lowering of systemic toxicity, and distinct tumor imaging in vivo","volume":"65","author":"Maeda","year":"2013","journal-title":"Adv. Drug Deliv. Rev."},{"key":"10.1016\/j.jconrel.2025.01.062_bb0025","doi-asserted-by":"crossref","first-page":"481","DOI":"10.1080\/17425247.2019.1604679","article-title":"Actively targeted nanocarriers for drug delivery to cancer cells","volume":"16","author":"Biffi","year":"2019","journal-title":"Expert Opin. Drug Deliv."},{"key":"10.1016\/j.jconrel.2025.01.062_bb0030","doi-asserted-by":"crossref","first-page":"2971","DOI":"10.1039\/c2cs15344k","article-title":"Targeted polymeric therapeutic nanoparticles: design, development and clinical translation","volume":"41","author":"Kamaly","year":"2012","journal-title":"Chem. Soc. Rev."},{"key":"10.1016\/j.jconrel.2025.01.062_bb0035","doi-asserted-by":"crossref","first-page":"4215","DOI":"10.1002\/adma.201101853","article-title":"Colorimetric biosensing using smart materials","volume":"23","author":"Song","year":"2011","journal-title":"Adv. Mater."},{"key":"10.1016\/j.jconrel.2025.01.062_bb0040","first-page":"5246","article-title":"Colorimetric biosensing using smart materials","volume":"105","author":"Guo","year":"2014","journal-title":"Colloids Surf. B: Biointerfaces"},{"key":"10.1016\/j.jconrel.2025.01.062_bb0045","doi-asserted-by":"crossref","first-page":"7195","DOI":"10.1021\/acsnano.5b02017","article-title":"The role of micelle size in tumor accumulation, penetration, and treatment","volume":"9","author":"Wang","year":"2015","journal-title":"ACS Nano"},{"key":"10.1016\/j.jconrel.2025.01.062_bb0050","doi-asserted-by":"crossref","first-page":"597","DOI":"10.1039\/C4NR05738D","article-title":"PSMA-mediated endosome escape-accelerating polymeric micelles for targeted therapy of prostate cancer and the real time tracing of their intracellular trafficking","volume":"7","author":"Gao","year":"2015","journal-title":"Nanoscale"},{"key":"10.1016\/j.jconrel.2025.01.062_bb0055","article-title":"A novel prostate-specific membrane-antigen (PSMA) targeted micelle-encapsulating Wogonin inhibits prostate cancer cell proliferation via inducing intrinsic apoptotic pathway","volume":"17","author":"Zhang","year":"2016","journal-title":"Int. J. Mol. Sci."},{"key":"10.1016\/j.jconrel.2025.01.062_bb0060","doi-asserted-by":"crossref","first-page":"436","DOI":"10.1016\/j.msec.2018.11.044","article-title":"Development of PSMA-targeted and core-crosslinked glycol chitosan micelles for docetaxel delivery in prostate cancer therapy","volume":"96","author":"Feng","year":"2019","journal-title":"Mater. Sci. Eng. C"},{"key":"10.1016\/j.jconrel.2025.01.062_bb0065","doi-asserted-by":"crossref","first-page":"14937","DOI":"10.1039\/C5CC05333A","article-title":"Stable and compact zwitterionic polydiacetylene micelles with tumor-targeting properties","volume":"51","author":"Theodorou","year":"2015","journal-title":"Chem. Commun."},{"key":"10.1016\/j.jconrel.2025.01.062_bb0070","doi-asserted-by":"crossref","first-page":"434","DOI":"10.1016\/j.ijpharm.2017.11.072","article-title":"Impact of the surface charge of polydiacetylene micelles on their interaction with human innate immune protein C1q and the complement system","volume":"536","author":"Thielens","year":"2018","journal-title":"Int. J. Pharm."},{"key":"10.1016\/j.jconrel.2025.01.062_bb0075","doi-asserted-by":"crossref","DOI":"10.1039\/C9TB01218D","article-title":"Mannose-coated polydiacetylene (PDA)-based nanomicelles: synthesis, interaction with concanavalin a and application in the water solubilization and delivery of hydrophobic molecules","volume":"7","author":"Romero-Ben","year":"2019","journal-title":"J. Mater. Chem. B"},{"key":"10.1016\/j.jconrel.2025.01.062_bb0080","first-page":"3192","article-title":"Five different anti-prostate-specific membrane antigen (PSMA) antibodies confirm PSMA expression in tumor-associated neovasculature","volume":"59","author":"Chang","year":"1999","journal-title":"Cancer Res."},{"key":"10.1016\/j.jconrel.2025.01.062_bb0085","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.abb.2004.12.003","article-title":"Expression of prostate specific membrane antigen in androgen-independent prostate cancer cell line PC-3","volume":"435","author":"Laidler","year":"2005","journal-title":"Arch. Biochem. Biophys."},{"key":"10.1016\/j.jconrel.2025.01.062_bb0090","doi-asserted-by":"crossref","first-page":"528","DOI":"10.1002\/jcb.10661","article-title":"Tumor target prostate specific membrane antigen (PSMA) and its regulation in prostate cancer","volume":"91","author":"Ghosh","year":"2004","journal-title":"J. Cell. Biochem."},{"key":"10.1016\/j.jconrel.2025.01.062_bb0095","doi-asserted-by":"crossref","first-page":"2477","DOI":"10.7150\/thno.18879","article-title":"PSMA-targeted theranostic nanocarrier for prostate cancer","volume":"7","author":"Flores","year":"2017","journal-title":"Theranostics"},{"key":"10.1016\/j.jconrel.2025.01.062_bb0100","doi-asserted-by":"crossref","first-page":"914","DOI":"10.2967\/jnumed.114.147413","article-title":"Preclinical evaluation of a tailor-made DOTA-conjugated PSMA inhibitor with optimized linker moiety for imaging and endoradiotherapy of prostate cancer","volume":"56","author":"Benesov\u00e1","year":"2015","journal-title":"J. Nucl. Med."},{"key":"10.1016\/j.jconrel.2025.01.062_bb0105","doi-asserted-by":"crossref","first-page":"2297","DOI":"10.1021\/acs.molpharmaceut.8b00152","article-title":"Preclinical development of novel PSMA-targeting Radioligands: modulation of albumin-binding properties to improve prostate Cancer therapy","volume":"15","author":"Umbricht","year":"2018","journal-title":"Mol. Pharm."},{"key":"10.1016\/j.jconrel.2025.01.062_bb0110","first-page":"3229","article-title":"Preclinical development and clinical translation of a PSMA-targeted docetaxel nanoparticle with a differentiated pharmacological profile","volume":"18","author":"Zamboni","year":"2012","journal-title":"Sci. Transl. Med."},{"key":"10.1016\/j.jconrel.2025.01.062_bb0115","doi-asserted-by":"crossref","DOI":"10.3390\/ijms23031158","article-title":"PSMA-targeting imaging and Theranostic agents\u2014current status and future perspective","volume":"23","author":"Debnath","year":"2022","journal-title":"Int. J. Mol. Sci."},{"key":"10.1016\/j.jconrel.2025.01.062_bb0120","doi-asserted-by":"crossref","first-page":"4099","DOI":"10.1016\/j.bmc.2014.05.061","article-title":"Rational design of urea-based glutamate carboxypeptidase II (GCPII) inhibitors as versatile tools for specific drug targeting and delivery","volume":"22","author":"Tykvart","year":"2014","journal-title":"Bioorg. Med. Chem."},{"key":"10.1016\/j.jconrel.2025.01.062_bb0125","doi-asserted-by":"crossref","first-page":"2340","DOI":"10.1016\/j.bmcl.2014.03.066","article-title":"Structural characterization of P1\u2032-diversified urea-based inhibitors of glutamate carboxypeptidase II","volume":"24","author":"Pavlicek","year":"2014","journal-title":"Bioorg. Med. Chem. Lett."},{"key":"10.1016\/j.jconrel.2025.01.062_bb0130","doi-asserted-by":"crossref","first-page":"4618","DOI":"10.1002\/jcp.29339","article-title":"PEG-PLA nanoparticles decorated with small-molecule PSMA ligand for targeted delivery of galbanic acid and docetaxel to prostate cancer cells","volume":"235","author":"Afsharzadeh","year":"2020","journal-title":"J. Cell. Physiol."},{"key":"10.1016\/j.jconrel.2025.01.062_bb0135","article-title":"A novel prostate-specific membrane-antigen (PSMA) targeted micelle-encapsulating Wogonin inhibits prostate cancer cell proliferation via inducing intrinsic apoptotic pathway","volume":"17","author":"Zhang","year":"2016","journal-title":"Int. J. Mol. Sci."},{"key":"10.1016\/j.jconrel.2025.01.062_bb0140","doi-asserted-by":"crossref","first-page":"2590","DOI":"10.1021\/acs.molpharmaceut.9b00181","article-title":"Evaluation of PSMA-targeted PAMAM dendrimer nanoparticles in a murine model of prostate Cancer","volume":"16","author":"Lesniak","year":"2019","journal-title":"Mol. Pharm."},{"key":"10.1016\/j.jconrel.2025.01.062_bb0145","doi-asserted-by":"crossref","first-page":"18094","DOI":"10.1002\/anie.202103444","article-title":"Ultrasmall Nanocapsules obtained by controlling Ostwald ripening","volume":"60","author":"Doan-Nguyen","year":"2021","journal-title":"Angew. Chem. Int. Ed."},{"key":"10.1016\/j.jconrel.2025.01.062_bb0150","doi-asserted-by":"crossref","first-page":"4665","DOI":"10.1021\/acs.nanolett.7b01171","article-title":"Balancing passive and active targeting to different tumor compartments using riboflavin-functionalized polymeric Nanocarriers","volume":"17","author":"Tsvetkova","year":"2017","journal-title":"Nano Lett."},{"key":"10.1016\/j.jconrel.2025.01.062_bb0155","doi-asserted-by":"crossref","DOI":"10.1039\/D3TB01713C","article-title":"Divergent approach to nanoscale glycomicelles and photo-responsive supramolecular glycogels. Implications for drug delivery and photoswitching lectin affinity","volume":"11","author":"Romero-Ben","year":"2023","journal-title":"J. Mater. Chem. B"},{"key":"10.1016\/j.jconrel.2025.01.062_bb0160","doi-asserted-by":"crossref","DOI":"10.3390\/ijms23042193","article-title":"Roles and regulation of BCL-xL in hematological malignancies","volume":"23","author":"Morales-Mart\u00ednez","year":"2022","journal-title":"Int. J. Mol. Sci."},{"key":"10.1016\/j.jconrel.2025.01.062_bb0165","doi-asserted-by":"crossref","DOI":"10.1186\/s12943-017-0713-9","article-title":"The oncogenic role of the In1-ghrelin splicing variant in prostate cancer aggressiveness","volume":"16","author":"Hormaechea-Agulla","year":"2017","journal-title":"Mol. Cancer"},{"key":"10.1016\/j.jconrel.2025.01.062_bb0170","doi-asserted-by":"crossref","DOI":"10.3390\/jcm8122056","article-title":"Clinical utility of ghrelin-o-acyltransferase (goat) enzyme as a diagnostic tool and potential therapeutic target in prostate cancer","volume":"8","author":"Jim\u00e9nez-Vacas","year":"2019","journal-title":"J. Clin. Med."},{"key":"10.1016\/j.jconrel.2025.01.062_bb0175","doi-asserted-by":"crossref","first-page":"73","DOI":"10.1016\/j.canlet.2004.05.003","article-title":"RNA expression of human telomerase subunits TR and TERT is differentially affected by melatonin receptor agonists in the MCF-7 tumor cell line","volume":"216","author":"Leon-Blanco","year":"2004","journal-title":"Cancer Lett."},{"key":"10.1016\/j.jconrel.2025.01.062_bb0180","doi-asserted-by":"crossref","DOI":"10.1016\/j.ebiom.2019.11.008","article-title":"Dysregulation of the splicing machinery is directly associated to aggressiveness of prostate cancer: SNRNP200, SRSF3 and SRRM1 as novel therapeutic targets for prostate cancer","volume":"51","author":"Jim\u00e9nez-Vacas","year":"2020","journal-title":"EBioMedicine"},{"key":"10.1016\/j.jconrel.2025.01.062_bb0185","doi-asserted-by":"crossref","first-page":"1418","DOI":"10.1038\/nbt1159","article-title":"Cell-specific targeting of nanoparticles by multivalent attachment of small molecules","volume":"23","author":"Weissleder","year":"2005","journal-title":"Nat. Biotechnol."},{"key":"10.1016\/j.jconrel.2025.01.062_bb0190","doi-asserted-by":"crossref","first-page":"3275","DOI":"10.1039\/C6CS00165C","article-title":"Organizing multivalency in carbohydrate recognition","volume":"45","author":"M\u00fcller","year":"2016","journal-title":"Chem. Soc. Rev."},{"key":"10.1016\/j.jconrel.2025.01.062_bb0195","doi-asserted-by":"crossref","DOI":"10.1039\/C5TB02488A","article-title":"Tuning of glyconanomaterial shape and size for selective bacterial cell agglutination","volume":"4","author":"Cid Mart\u00edn","year":"2016","journal-title":"J. Mater. Chem. B"},{"key":"10.1016\/j.jconrel.2025.01.062_bb0200","doi-asserted-by":"crossref","first-page":"815","DOI":"10.1038\/nnano.2011.166","article-title":"Accumulation of sub-100 nm polymeric micelles in poorly permeable tumours depends on size","volume":"6","author":"Cabral","year":"2011","journal-title":"Nat. Nanotechnol."},{"key":"10.1016\/j.jconrel.2025.01.062_bb0205","doi-asserted-by":"crossref","first-page":"772","DOI":"10.1021\/jm9905559","article-title":"Dual function glutamate-related ligands: discovery of a novel, potent inhibitor of glutamate carboxypeptidase II possessing mGluR3 agonist activity [3]","volume":"43","author":"Nan","year":"2000","journal-title":"J. Med. Chem."},{"key":"10.1016\/j.jconrel.2025.01.062_bb0210","doi-asserted-by":"crossref","first-page":"2004","DOI":"10.1002\/1521-3773(20010601)40:11<2004::AID-ANIE2004>3.0.CO;2-5","article-title":"Click chemistry: diverse chemical function from a few good reactions","volume":"40","author":"Kolb","year":"2001","journal-title":"Angew. Chem. Int. Ed."},{"key":"10.1016\/j.jconrel.2025.01.062_bb0215","doi-asserted-by":"crossref","DOI":"10.1002\/chem.201002236","article-title":"Copper-catalyzed azide-alkyne cycloaddition in the synthesis of polydiacetylene: \u201cclick glycoliposome\u201d as biosensors for the specific detection of lectins","volume":"17","author":"Leal","year":"2011","journal-title":"Chem. Eur. J."},{"key":"10.1016\/j.jconrel.2025.01.062_bb0220","doi-asserted-by":"crossref","first-page":"248","DOI":"10.1016\/j.jcis.2005.07.006","article-title":"Pyrene absorption can be a convenient method for probing critical micellar concentration (cmc) and indexing micellar polarity","volume":"294","author":"Basu Ray","year":"2006","journal-title":"J. Colloid Interface Sci."},{"key":"10.1016\/j.jconrel.2025.01.062_bb0225","doi-asserted-by":"crossref","first-page":"4789","DOI":"10.1021\/acsabm.0c01679","article-title":"PDA-based Glyconanomicelles for hepatocellular carcinoma cells active targeting via mannose and Asialoglycoprotein receptors","volume":"4","author":"Negrete","year":"2021","journal-title":"ACS Appl. Bio Mater."},{"key":"10.1016\/j.jconrel.2025.01.062_bb0230","doi-asserted-by":"crossref","first-page":"6259","DOI":"10.1073\/pnas.1600420113","article-title":"Resistance to docetaxel in prostate cancer is associated with androgen receptor activation and loss of KDM5D expression","volume":"113","author":"Komura","year":"2016","journal-title":"Proc. Natl. Acad. Sci. USA"},{"key":"10.1016\/j.jconrel.2025.01.062_bb0235","doi-asserted-by":"crossref","first-page":"1158","DOI":"10.1002\/pros.21331","article-title":"Resistance to docetaxel-induced apoptosis in prostate cancer cells by p38\/p53\/p21 signaling","volume":"71","author":"Gan","year":"2011","journal-title":"Prostate"},{"key":"10.1016\/j.jconrel.2025.01.062_bb0240","doi-asserted-by":"crossref","first-page":"2528","DOI":"10.1111\/febs.13761","article-title":"Comparison of human glutamate carboxypeptidases II and III reveals their divergent substrate specificities","volume":"283","author":"Navr\u00e1til","year":"2016","journal-title":"FEBS J."},{"key":"10.1016\/j.jconrel.2025.01.062_bb0245","doi-asserted-by":"crossref","first-page":"448","DOI":"10.1016\/S0140-6736(87)90977-9","article-title":"Prognostic relevance of tumour-cell growth fraction in malignant non-HODGKIN'S lymphomas","volume":"330","author":"Gerdes","year":"1987","journal-title":"Lancet"},{"key":"10.1016\/j.jconrel.2025.01.062_bb0250","doi-asserted-by":"crossref","first-page":"13","DOI":"10.1002\/ijc.2910310104","article-title":"Production of a mouse monoclonal antibody reactive with a human nuclear antigen associated with cell proliferation","volume":"31","author":"Gerdes","year":"1983","journal-title":"Int. J. Cancer"},{"key":"10.1016\/j.jconrel.2025.01.062_bb0255","doi-asserted-by":"crossref","first-page":"153","DOI":"10.1038\/nrc2602","article-title":"Cell cycle, CDKs and cancer: a changing paradigm","volume":"9","author":"Malumbres","year":"2009","journal-title":"Nat. Rev. Cancer"},{"key":"10.1016\/j.jconrel.2025.01.062_bb0260","doi-asserted-by":"crossref","first-page":"249","DOI":"10.1016\/j.phrs.2016.03.012","article-title":"Cyclin-dependent protein kinase inhibitors including palbociclib as anticancer drugs","volume":"107","author":"Roskoski","year":"2016","journal-title":"Pharmacol. Res."},{"key":"10.1016\/j.jconrel.2025.01.062_bb0265","doi-asserted-by":"crossref","DOI":"10.1038\/s41419-020-2589-7","article-title":"BCL-xL\/BCL2L1 is a critical anti-apoptotic protein that promotes the survival of differentiating pancreatic cells from human pluripotent stem cells","volume":"11","author":"Loo","year":"2020","journal-title":"Cell Death Dis."},{"key":"10.1016\/j.jconrel.2025.01.062_bb0270","doi-asserted-by":"crossref","first-page":"597","DOI":"10.1016\/0092-8674(93)90508-N","article-title":"Bcl-x, a bcl-2-related gene that functions as a dominant regulator of apoptotic cell death","volume":"74","author":"Boise","year":"1993","journal-title":"Cell"},{"key":"10.1016\/j.jconrel.2025.01.062_bb0275","doi-asserted-by":"crossref","DOI":"10.1101\/cshperspect.a026062","article-title":"Tumor-suppressor functions of the TP53 pathway","volume":"6","author":"Aubrey","year":"2016","journal-title":"Cold Spring Harb. Perspect. Med."},{"key":"10.1016\/j.jconrel.2025.01.062_bb0280","doi-asserted-by":"crossref","first-page":"522","DOI":"10.1002\/path.4321","article-title":"Effects of TP53 mutational status on gene expression patterns across 10 human cancer types","volume":"232","author":"Parikh","year":"2014","journal-title":"J. Pathol."},{"key":"10.1016\/j.jconrel.2025.01.062_bb0285","doi-asserted-by":"crossref","unstructured":"A. Zuliani, V. Ramos, A. Escudero, N. Khiar, \u201cSweet MOFs\u201d: exploring the potential and restraints of integrating carbohydrates with metal\u2013organic frameworks for biomedical applications, nanoscale horizons, Advance article. doi: https:\/\/doi.org\/10.1039\/D4NH00525B.","DOI":"10.1039\/D4NH00525B"}],"container-title":["Journal of Controlled Release"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0168365925000732?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0168365925000732?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,4,30]],"date-time":"2026-04-30T00:45:13Z","timestamp":1777509913000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0168365925000732"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,3]]},"references-count":57,"alternative-id":["S0168365925000732"],"URL":"https:\/\/doi.org\/10.1016\/j.jconrel.2025.01.062","relation":{},"ISSN":["0168-3659"],"issn-type":[{"value":"0168-3659","type":"print"}],"subject":[],"published":{"date-parts":[[2025,3]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"PSMA-targeted delivery of docetaxel in prostate cancer using small-sized PDA-based micellar nanovectors","name":"articletitle","label":"Article Title"},{"value":"Journal of Controlled Release","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.jconrel.2025.01.062","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2025 The Authors. Published by Elsevier B.V.","name":"copyright","label":"Copyright"}]}}