{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,17]],"date-time":"2026-08-17T18:38:00Z","timestamp":1786991880954,"version":"build-2736575974"},"reference-count":77,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2025,4,1]],"date-time":"2025-04-01T00:00:00Z","timestamp":1743465600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2025,4,1]],"date-time":"2025-04-01T00:00:00Z","timestamp":1743465600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2026,2,11]],"date-time":"2026-02-11T00:00:00Z","timestamp":1770768000000},"content-version":"am","delay-in-days":316,"URL":"http:\/\/www.elsevier.com\/open-access\/userlicense\/1.0\/"},{"start":{"date-parts":[[2025,4,1]],"date-time":"2025-04-01T00:00:00Z","timestamp":1743465600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2025,4,1]],"date-time":"2025-04-01T00:00:00Z","timestamp":1743465600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2025,4,1]],"date-time":"2025-04-01T00:00:00Z","timestamp":1743465600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2025,4,1]],"date-time":"2025-04-01T00:00:00Z","timestamp":1743465600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2025,4,1]],"date-time":"2025-04-01T00:00:00Z","timestamp":1743465600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"funder":[{"DOI":"10.13039\/100000002","name":"National Institutes of Health","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000054","name":"National Institutes of Health National Cancer Institute","doi-asserted-by":"publisher","award":["R01-CA257837"],"award-info":[{"award-number":["R01-CA257837"]}],"id":[{"id":"10.13039\/100000054","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Journal of Controlled Release"],"published-print":{"date-parts":[[2025,4]]},"DOI":"10.1016\/j.jconrel.2025.02.009","type":"journal-article","created":{"date-parts":[[2025,2,11]],"date-time":"2025-02-11T12:13:36Z","timestamp":1739276016000},"page":"457-468","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":14,"special_numbering":"C","title":["Crystallization of supersaturated PEG-b-PLA for the production of drug-loaded polymeric micelles"],"prefix":"10.1016","volume":"380","author":[{"given":"Morteza","family":"Rasoulianboroujeni","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rae Hyung","family":"Kang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Maraya","family":"Klukas","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Glen S.","family":"Kwon","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.jconrel.2025.02.009_bb0005","doi-asserted-by":"crossref","first-page":"312","DOI":"10.1016\/j.jconrel.2021.02.031","article-title":"Polymeric micelles in drug delivery: an insight of the techniques for their characterization and assessment in biorelevant conditions","volume":"332","author":"Ghezzi","year":"2021","journal-title":"J. Control. Release"},{"key":"10.1016\/j.jconrel.2025.02.009_bb0010","doi-asserted-by":"crossref","first-page":"127","DOI":"10.1016\/j.jconrel.2021.02.016","article-title":"Polymeric micelles in cancer therapy: state of the art","volume":"332","author":"Ghosh","year":"2021","journal-title":"J. Control. Release"},{"key":"10.1016\/j.jconrel.2025.02.009_bb0015","doi-asserted-by":"crossref","first-page":"718","DOI":"10.1016\/j.jconrel.2020.03.002","article-title":"Polymer nanomedicines based on micelle-forming amphiphilic or water-soluble polymer-doxorubicin conjugates: comparative study of in vitro and in vivo properties related to the polymer carrier structure, composition, and hydrodynamic properties","volume":"321","author":"Braunov\u00e1","year":"2020","journal-title":"J. Control. Release"},{"key":"10.1016\/j.jconrel.2025.02.009_bb0020","doi-asserted-by":"crossref","first-page":"496","DOI":"10.1016\/j.jconrel.2023.09.050","article-title":"IDO-triggered swellable polymeric micelles for IDO inhibition and targeted cancer immunotherapy","volume":"363","author":"Park","year":"2023","journal-title":"J. Control. Release"},{"issue":"1","key":"10.1016\/j.jconrel.2025.02.009_bb0025","doi-asserted-by":"crossref","first-page":"1409","DOI":"10.1021\/acsnano.1c09456","article-title":"Potential-independent intracellular drug delivery and mitochondrial targeting","volume":"16","author":"Liu","year":"2021","journal-title":"ACS Nano"},{"issue":"22","key":"10.1016\/j.jconrel.2025.02.009_bb0030","doi-asserted-by":"crossref","first-page":"22430","DOI":"10.1021\/acsnano.3c05181","article-title":"Cell-selective binding zwitterionic polymeric micelles boost the delivery efficiency of antibiotics","volume":"17","author":"Yu","year":"2023","journal-title":"ACS Nano"},{"issue":"24","key":"10.1016\/j.jconrel.2025.02.009_bb0035","doi-asserted-by":"crossref","first-page":"24654","DOI":"10.1021\/acsnano.3c03305","article-title":"Pirfenidone-loaded polymeric micelles as an effective mechanotherapeutic to potentiate immunotherapy in mouse tumor models","volume":"17","author":"Mpekris","year":"2023","journal-title":"ACS Nano"},{"issue":"2","key":"10.1016\/j.jconrel.2025.02.009_bb0040","doi-asserted-by":"crossref","first-page":"145","DOI":"10.1517\/17425240903436479","article-title":"Polymeric micelles as a new drug carrier system and their required considerations for clinical trials","volume":"7","author":"Yokoyama","year":"2010","journal-title":"Expert Opin. Drug Deliv."},{"issue":"1","key":"10.1016\/j.jconrel.2025.02.009_bb0045","doi-asserted-by":"crossref","first-page":"11","DOI":"10.1016\/j.jconrel.2007.07.008","article-title":"What are determining factors for stable drug incorporation into polymeric micelle carriers? Consideration on physical and chemical characters of the micelle inner core","volume":"123","author":"Yamamoto","year":"2007","journal-title":"J. Control. Release"},{"issue":"5","key":"10.1016\/j.jconrel.2025.02.009_bb0050","doi-asserted-by":"crossref","first-page":"759","DOI":"10.1016\/S0169-409X(02)00047-9","article-title":"Pluronic\u00ae block copolymers for overcoming drug resistance in cancer","volume":"54","author":"Kabanov","year":"2002","journal-title":"Adv. Drug Deliv. Rev."},{"issue":"1\u20132","key":"10.1016\/j.jconrel.2025.02.009_bb0055","doi-asserted-by":"crossref","first-page":"75","DOI":"10.1016\/S0168-3659(03)00211-6","article-title":"An essential relationship between ATP depletion and chemosensitizing activity of Pluronic\u00ae block copolymers","volume":"91","author":"Kabanov","year":"2003","journal-title":"J. Control. Release"},{"issue":"38","key":"10.1016\/j.jconrel.2025.02.009_bb0060","doi-asserted-by":"crossref","first-page":"4788","DOI":"10.1002\/ange.200250653","article-title":"Design of environment-sensitive supramolecular assemblies for intracellular drug delivery: polymeric micelles that are responsive to intracellular pH change","volume":"115","author":"Bae","year":"2003","journal-title":"Angew. Chem."},{"issue":"2","key":"10.1016\/j.jconrel.2025.02.009_bb0065","doi-asserted-by":"crossref","first-page":"241","DOI":"10.1007\/s10549-007-9591-y","article-title":"Multicenter phase II trial of Genexol-PM, a Cremophor-free, polymeric micelle formulation of paclitaxel, in patients with metastatic breast cancer","volume":"108","author":"Lee","year":"2008","journal-title":"Breast Cancer Res. Treat."},{"issue":"11","key":"10.1016\/j.jconrel.2025.02.009_bb0070","doi-asserted-by":"crossref","first-page":"3708","DOI":"10.1158\/1078-0432.CCR-03-0655","article-title":"Phase I and pharmacokinetic study of Genexol-PM, a cremophor-free, polymeric micelle-formulated paclitaxel, in patients with advanced malignancies","volume":"10","author":"Kim","year":"2004","journal-title":"Clin. Cancer Res."},{"key":"10.1016\/j.jconrel.2025.02.009_bb0075","doi-asserted-by":"crossref","first-page":"80","DOI":"10.1016\/j.addr.2020.09.009","article-title":"Polymeric micelles for the delivery of poorly soluble drugs: from nanoformulation to clinical approval","volume":"156","author":"Hwang","year":"2020","journal-title":"Adv. Drug Deliv. Rev."},{"key":"10.1016\/j.jconrel.2025.02.009_bb0080","doi-asserted-by":"crossref","first-page":"241","DOI":"10.1007\/s10549-007-9591-y","article-title":"Multicenter phase II trial of Genexol-PM, a Cremophor-free, polymeric micelle formulation of paclitaxel, in patients with metastatic breast cancer","volume":"108","author":"Lee","year":"2008","journal-title":"Breast Cancer Res. Treat."},{"key":"10.1016\/j.jconrel.2025.02.009_bb0085","doi-asserted-by":"crossref","first-page":"1029","DOI":"10.1007\/s10637-010-9399-1","article-title":"A phase 2 study of SP1049C, doxorubicin in P-glycoprotein-targeting pluronics, in patients with advanced adenocarcinoma of the esophagus and gastroesophageal junction","volume":"29","author":"Valle","year":"2011","journal-title":"Investig. New Drugs"},{"key":"10.1016\/j.jconrel.2025.02.009_bb0090","doi-asserted-by":"crossref","first-page":"1621","DOI":"10.1007\/s10637-011-9709-2","article-title":"Phase II study of NK105, a paclitaxel-incorporating micellar nanoparticle, for previously treated advanced or recurrent gastric cancer","volume":"30","author":"Kato","year":"2012","journal-title":"Investig. New Drugs"},{"issue":"5","key":"10.1016\/j.jconrel.2025.02.009_bb0095","doi-asserted-by":"crossref","first-page":"688","DOI":"10.3390\/ma11050688","article-title":"Polymeric micelles of biodegradable diblock copolymers: enhanced encapsulation of hydrophobic drugs","volume":"11","author":"Hussein","year":"2018","journal-title":"Materials"},{"issue":"1\u20132","key":"10.1016\/j.jconrel.2025.02.009_bb0100","doi-asserted-by":"crossref","first-page":"155","DOI":"10.1016\/S0168-3659(01)00477-1","article-title":"Micelles self-assembled from poly (ethylene oxide)-block-poly (N-hexyl stearate L-aspartamide) by a solvent evaporation method: effect on the solubilization and haemolytic activity of amphotericin B","volume":"77","author":"Lavasanifar","year":"2001","journal-title":"J. Control. Release"},{"key":"10.1016\/j.jconrel.2025.02.009_bb0105","doi-asserted-by":"crossref","first-page":"201","DOI":"10.1016\/j.jconrel.2014.12.027","article-title":"Esterase-activatable \u03b2-lapachone prodrug micelles for NQO1-targeted lung cancer therapy","volume":"200","author":"Ma","year":"2015","journal-title":"J. Control. Release"},{"issue":"6","key":"10.1016\/j.jconrel.2025.02.009_bb0110","doi-asserted-by":"crossref","first-page":"925","DOI":"10.1016\/j.nano.2011.11.005","article-title":"Paclitaxel-loaded polymeric micelles based on poly (\u025b-caprolactone)-poly (ethylene glycol)-poly (\u025b-caprolactone) triblock copolymers: in vitro and in vivo evaluation","volume":"8","author":"Zhang","year":"2012","journal-title":"Nanomedicine"},{"issue":"18","key":"10.1016\/j.jconrel.2025.02.009_bb0115","doi-asserted-by":"crossref","first-page":"9229","DOI":"10.1021\/la701157j","article-title":"Micellization and gelation of mixed copolymers P123 and F127 in aqueous solution","volume":"23","author":"Chaibundit","year":"2007","journal-title":"Langmuir"},{"issue":"7","key":"10.1016\/j.jconrel.2025.02.009_bb0120","doi-asserted-by":"crossref","first-page":"7406","DOI":"10.1021\/acsnano.8b04205","article-title":"Stereocomplex prodrugs of oligo (lactic acid) n-gemcitabine in poly (ethylene glycol)-block-poly (D, L-lactic acid) micelles for improved physical stability and enhanced antitumor efficacy","volume":"12","author":"Tam","year":"2018","journal-title":"ACS Nano"},{"issue":"28","key":"10.1016\/j.jconrel.2025.02.009_bb0125","doi-asserted-by":"crossref","first-page":"8674","DOI":"10.1021\/jacs.6b03995","article-title":"Oligo (lactic acid) n-paclitaxel prodrugs for poly (ethylene glycol)-block-poly (lactic acid) micelles: loading, release, and backbiting conversion for anticancer activity","volume":"138","author":"Tam","year":"2016","journal-title":"J. Am. Chem. Soc."},{"issue":"6","key":"10.1016\/j.jconrel.2025.02.009_bb0130","doi-asserted-by":"crossref","first-page":"923","DOI":"10.1002\/polb.10739","article-title":"Preparation of block copolymer vesicles in solution","volume":"42","author":"Lim Soo","year":"2004","journal-title":"J. Polym. Sci. B Polym. Phys."},{"issue":"50","key":"10.1016\/j.jconrel.2025.02.009_bb0135","doi-asserted-by":"crossref","first-page":"15350","DOI":"10.1021\/acs.langmuir.8b02992","article-title":"From tunable DNA\/polymer self-assembly to tailorable and morphologically pure core\u2013shell nanofibers","volume":"34","author":"Wang","year":"2018","journal-title":"Langmuir"},{"issue":"1\u20133","key":"10.1016\/j.jconrel.2025.02.009_bb0140","doi-asserted-by":"crossref","first-page":"155","DOI":"10.1016\/S0168-3659(01)00492-8","article-title":"Process design for efficient and controlled drug incorporation into polymeric micelle carrier systems","volume":"78","author":"Kohori","year":"2002","journal-title":"J. Control. Release"},{"key":"10.1016\/j.jconrel.2025.02.009_bb0145","doi-asserted-by":"crossref","first-page":"137711","DOI":"10.1016\/j.cplett.2020.137711","article-title":"How is a micelle formed from amphiphilic polymers in a dialysis process: insight from mesoscopic studies","volume":"754","author":"Feng","year":"2020","journal-title":"Chem. Phys. Lett."},{"issue":"43","key":"10.1016\/j.jconrel.2025.02.009_bb0150","doi-asserted-by":"crossref","first-page":"39603","DOI":"10.1021\/acsami.9b13851","article-title":"Overcoming the anatomical and physiological barriers in topical eye surface medication using a peptide-decorated polymeric micelle","volume":"11","author":"Lin","year":"2019","journal-title":"ACS Appl. Mater. Interfaces"},{"issue":"7","key":"10.1016\/j.jconrel.2025.02.009_bb0155","doi-asserted-by":"crossref","first-page":"1184","DOI":"10.1023\/B:PHAM.0000033005.25698.9c","article-title":"Preparation and drug loading of poly (ethylene glycol)-block-poly (\u03b5-caprolactone) micelles through the evaporation of a cosolvent azeotrope","volume":"21","author":"Jette","year":"2004","journal-title":"Pharm. Res."},{"issue":"1\u20132","key":"10.1016\/j.jconrel.2025.02.009_bb0160","doi-asserted-by":"crossref","first-page":"190","DOI":"10.1016\/j.ijpharm.2008.12.033","article-title":"Morphology and in vitro release kinetics of drug-loaded micelles based on well-defined PMPC\u2013b\u2013PBMA copolymer","volume":"371","author":"Chu","year":"2009","journal-title":"Int. J. Pharm."},{"issue":"2","key":"10.1016\/j.jconrel.2025.02.009_bb0165","doi-asserted-by":"crossref","first-page":"289","DOI":"10.1016\/j.jconrel.2005.02.010","article-title":"Enhancement of oral bioavailability of poorly water-soluble drugs by poly (ethylene glycol)-block-poly (alkyl acrylate-co-methacrylic acid) self-assemblies","volume":"104","author":"Sant","year":"2005","journal-title":"J. Control. Release"},{"issue":"1\u20133","key":"10.1016\/j.jconrel.2025.02.009_bb0170","doi-asserted-by":"crossref","first-page":"143","DOI":"10.1016\/S0168-3659(99)00133-9","article-title":"Doxorubicin-loaded poly (ethylene glycol)\u2013poly (\u03b2-benzyl-l-aspartate) copolymer micelles: their pharmaceutical characteristics and biological significance","volume":"64","author":"Kataoka","year":"2000","journal-title":"J. Control. Release"},{"key":"10.1016\/j.jconrel.2025.02.009_bb0175","doi-asserted-by":"crossref","first-page":"350","DOI":"10.1016\/j.jconrel.2022.08.032","article-title":"Production of paclitaxel-loaded PEG-b-PLA micelles using PEG for drug loading and freeze-drying","volume":"350","author":"Rasoulianboroujeni","year":"2022","journal-title":"J. Control. Release"},{"issue":"6","key":"10.1016\/j.jconrel.2025.02.009_bb0180","doi-asserted-by":"crossref","first-page":"2000212","DOI":"10.1002\/biot.202000212","article-title":"Lyophilization stabilizes clinical-stage core-crosslinked polymeric micelles to overcome cold chain supply challenges","volume":"16","author":"Ojha","year":"2021","journal-title":"Biotechnol. J."},{"key":"10.1016\/j.jconrel.2025.02.009_bb0185","doi-asserted-by":"crossref","first-page":"159","DOI":"10.1016\/j.ejpb.2023.01.020","article-title":"Polymer micelles for the protection and delivery of specialized pro-resolving mediators","volume":"184","author":"de Prinse","year":"2023","journal-title":"Eur. J. Pharm. Biopharm."},{"issue":"22","key":"10.1016\/j.jconrel.2025.02.009_bb0190","doi-asserted-by":"crossref","first-page":"2191","DOI":"10.1016\/0142-9612(96)00049-X","article-title":"Stability study of nanoparticles of poly (\u025b-caprolactone), poly (d, l-lactide) and poly (d, l-lactide-co-glycolide)","volume":"17","author":"Lemoine","year":"1996","journal-title":"Biomaterials"},{"issue":"6","key":"10.1016\/j.jconrel.2025.02.009_bb0195","doi-asserted-by":"crossref","first-page":"456","DOI":"10.1016\/j.addr.2011.02.001","article-title":"Physical and chemical stability of drug nanoparticles","volume":"63","author":"Wu","year":"2011","journal-title":"Adv. Drug Deliv. Rev."},{"key":"10.1016\/j.jconrel.2025.02.009_bb0200","doi-asserted-by":"crossref","first-page":"75","DOI":"10.1016\/j.jconrel.2016.01.034","article-title":"Facts and evidences on the lyophilization of polymeric nanoparticles for drug delivery","volume":"225","author":"Fonte","year":"2016","journal-title":"J. Control. Release"},{"key":"10.1016\/j.jconrel.2025.02.009_bb0205","series-title":"Freeze-Drying\/Lyophilization of Pharmaceutical and Biological Products","first-page":"302","article-title":"Regulatory control of freeze-dried products: Importance and evaluation of residual moisture","author":"May","year":"2016"},{"issue":"6","key":"10.1016\/j.jconrel.2025.02.009_bb0210","doi-asserted-by":"crossref","first-page":"962","DOI":"10.1023\/B:PHAM.0000029284.40637.69","article-title":"A novel one-step drug-loading procedure for water-soluble amphiphilic nanocarriers","volume":"21","author":"Fournier","year":"2004","journal-title":"Pharm. Res."},{"issue":"1\u20133","key":"10.1016\/j.jconrel.2025.02.009_bb0215","doi-asserted-by":"crossref","first-page":"169","DOI":"10.1016\/j.jconrel.2005.09.034","article-title":"Block copolymer micelles: preparation, characterization and application in drug delivery","volume":"109","author":"Gaucher","year":"2005","journal-title":"J. Control. Release"},{"issue":"9","key":"10.1016\/j.jconrel.2025.02.009_bb0220","doi-asserted-by":"crossref","first-page":"1257","DOI":"10.1080\/17425247.2016.1182485","article-title":"Polyethylene glycol (PEG): a versatile polymer for pharmaceutical applications","volume":"13","author":"D\u2019souza","year":"2016","journal-title":"Expert Opin. Drug Deliv."},{"issue":"2","key":"10.1016\/j.jconrel.2025.02.009_bb0225","doi-asserted-by":"crossref","first-page":"219","DOI":"10.1016\/j.ijpharm.2015.11.015","article-title":"Polyethylene glycols in oral and parenteral formulations\u2014a critical review","volume":"496","author":"Gullapalli","year":"2015","journal-title":"Int. J. Pharm."},{"issue":"37","key":"10.1016\/j.jconrel.2025.02.009_bb0230","doi-asserted-by":"crossref","first-page":"7925","DOI":"10.1021\/acs.jpcb.3c03854","article-title":"Entropy-driven liquid\u2013liquid phase separation transition to polymeric micelles","volume":"127","author":"Rasoulianboroujeni","year":"2023","journal-title":"J. Phys. Chem. B"},{"key":"10.1016\/j.jconrel.2025.02.009_bb0235","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1007\/s11095-019-2600-0","article-title":"Oligo (lactic acid) 8-rapamycin prodrug-loaded poly (ethylene glycol)-block-poly (lactic acid) micelles for injection","volume":"36","author":"Tam","year":"2019","journal-title":"Pharm. Res."},{"issue":"10","key":"10.1016\/j.jconrel.2025.02.009_bb0240","doi-asserted-by":"crossref","first-page":"2745","DOI":"10.3390\/nano11102745","article-title":"Oligo (lactic acid) 8-docetaxel prodrug-loaded PEG-b-PLA micelles for prostate cancer","volume":"11","author":"Repp","year":"2021","journal-title":"Nanomaterials"},{"issue":"3","key":"10.1016\/j.jconrel.2025.02.009_bb0245","doi-asserted-by":"crossref","first-page":"455","DOI":"10.1002\/pol.20190077","article-title":"Confined crystallization, melting behavior and morphology in PEG-b-PLA diblock copolymers: amorphous versus crystalline PLA","volume":"58","author":"Bao","year":"2020","journal-title":"J. Polym. Sci."},{"issue":"23","key":"10.1016\/j.jconrel.2025.02.009_bb0250","doi-asserted-by":"crossref","first-page":"8219","DOI":"10.1021\/ma980747y","article-title":"Determination of the equilibrium melting temperature of polymer crystals: linear and nonlinear Hoffman\u2212 Weeks extrapolations","volume":"31","author":"Marand","year":"1998","journal-title":"Macromolecules"},{"issue":"8","key":"10.1016\/j.jconrel.2025.02.009_bb0255","doi-asserted-by":"crossref","first-page":"1520","DOI":"10.1021\/ma00138a017","article-title":"Melting point depression in crystalline\/compatible polymer blends","volume":"17","author":"Rim","year":"1984","journal-title":"Macromolecules"},{"issue":"32","key":"10.1016\/j.jconrel.2025.02.009_bb0260","doi-asserted-by":"crossref","first-page":"16059","DOI":"10.1021\/jp062124p","article-title":"Phase diagrams of binary crystalline\u2212 crystalline polymer blends","volume":"110","author":"Matkar","year":"2006","journal-title":"J. Phys. Chem. B"},{"issue":"6","key":"10.1016\/j.jconrel.2025.02.009_bb0265","doi-asserted-by":"crossref","first-page":"909","DOI":"10.1021\/ma60048a040","article-title":"Melting point depression and kinetic effects of cooling on crystallization in poly (vinylidene fluoride)-poly (methyl methacrylate) mixtures","volume":"8","author":"Nishi","year":"1975","journal-title":"Macromolecules"},{"issue":"84","key":"10.1016\/j.jconrel.2025.02.009_bb0270","doi-asserted-by":"crossref","first-page":"68881","DOI":"10.1039\/C5RA11842E","article-title":"Novel solid\u2013solid phase change materials with biodegradable trihydroxy surfactants for thermal energy storage","volume":"5","author":"Fu","year":"2015","journal-title":"RSC Adv."},{"key":"10.1016\/j.jconrel.2025.02.009_bb0275","doi-asserted-by":"crossref","first-page":"177","DOI":"10.1016\/j.solmat.2015.12.009","article-title":"Solvent-free synthesis and properties of novel solid\u2013solid phase change materials with biodegradable castor oil for thermal energy storage","volume":"147","author":"Liu","year":"2016","journal-title":"Sol. Energy Mater. Sol. Cells"},{"key":"10.1016\/j.jconrel.2025.02.009_bb0280","doi-asserted-by":"crossref","first-page":"343","DOI":"10.1016\/j.jaap.2017.07.016","article-title":"Characterizations of PLA-PEG blends involving organically modified montmorillonite","volume":"127","author":"Ozdemir","year":"2017","journal-title":"J. Anal. Appl. Pyrolysis"},{"issue":"1","key":"10.1016\/j.jconrel.2025.02.009_bb0285","first-page":"1","article-title":"Synthesis, characterization, and crystallization behaviors of poly (D-lactic acid)-based triblock copolymer","volume":"10","author":"Wu","year":"2020","journal-title":"Sci. Rep."},{"issue":"7","key":"10.1016\/j.jconrel.2025.02.009_bb0290","doi-asserted-by":"crossref","DOI":"10.1002\/app.43027","article-title":"Preparation and characterization of poly (ethylene glycol) stabilized nano silver particles by a mechanochemical assisted ball mill process","volume":"133","author":"Jayaramudu","year":"2016","journal-title":"J. Appl. Polym. Sci."},{"key":"10.1016\/j.jconrel.2025.02.009_bb0295","doi-asserted-by":"crossref","first-page":"269","DOI":"10.1016\/j.cej.2014.08.030","article-title":"Removal of congo red and methyl violet from water using nano clay filled composite hydrogels of poly acrylic acid and polyethylene glycol","volume":"260","author":"Bhattacharyya","year":"2015","journal-title":"Chem. Eng. J."},{"issue":"6","key":"10.1016\/j.jconrel.2025.02.009_bb0300","doi-asserted-by":"crossref","first-page":"1160","DOI":"10.1002\/pc.22763","article-title":"Preparation, characterization, and electrical properties of ZSM-5\/PEG composite particles","volume":"35","author":"Hussein","year":"2014","journal-title":"Polym. Compos."},{"issue":"6","key":"10.1016\/j.jconrel.2025.02.009_bb0305","doi-asserted-by":"crossref","first-page":"516","DOI":"10.1016\/j.progpolymsci.2009.03.002","article-title":"Crystallization and morphology of biodegradable or biostable single and double crystalline block copolymers","volume":"34","author":"Castillo","year":"2009","journal-title":"Prog. Polym. Sci."},{"issue":"12","key":"10.1016\/j.jconrel.2025.02.009_bb0310","doi-asserted-by":"crossref","first-page":"3937","DOI":"10.1016\/j.eurpolymj.2013.08.025","article-title":"Evolution of concentric spherulites in crystalline-crystalline poly (3-hydroxybutyrate-co-3-hydroxyvalerate)-b-poly (ethylene glycol) copolymers","volume":"49","author":"Liu","year":"2013","journal-title":"Eur. Polym. J."},{"issue":"7","key":"10.1016\/j.jconrel.2025.02.009_bb0315","doi-asserted-by":"crossref","first-page":"3233","DOI":"10.1016\/S0032-3861(00)00597-8","article-title":"Appearance of double spherulites like concentric circles for poly (\u03f5-caprolactone)-block-poly (ethylene glycol)-block-poly (\u03f5-caprolactone)","volume":"42","author":"Shiomi","year":"2001","journal-title":"Polymer"},{"issue":"6","key":"10.1016\/j.jconrel.2025.02.009_bb0320","doi-asserted-by":"crossref","first-page":"673","DOI":"10.1002\/macp.201200673","article-title":"Unconventional non-birefringent or birefringent concentric ring-banded spherulites in poly (l-lactic acid) thin films","volume":"214","author":"Nurkhamidah","year":"2013","journal-title":"Macromol. Chem. Phys."},{"issue":"5","key":"10.1016\/j.jconrel.2025.02.009_bb0325","doi-asserted-by":"crossref","first-page":"1783","DOI":"10.1021\/ma402579d","article-title":"Tuning radial lamellar packing and orientation into diverse ring-banded spherulites: effects of structural feature and crystallization condition","volume":"47","author":"Li","year":"2014","journal-title":"Macromolecules"},{"issue":"21","key":"10.1016\/j.jconrel.2025.02.009_bb0330","doi-asserted-by":"crossref","first-page":"9015","DOI":"10.1016\/j.polymer.2005.07.024","article-title":"In situ AFM study of the growth of banded hedritic structures in thin films of isotactic polystyrene","volume":"46","author":"Duan","year":"2005","journal-title":"Polymer"},{"issue":"18","key":"10.1016\/j.jconrel.2025.02.009_bb0335","doi-asserted-by":"crossref","first-page":"4776","DOI":"10.1016\/j.polymer.2013.06.031","article-title":"Crystallization and higher-order structure of multicomponent polymeric systems","volume":"54","author":"Takeshita","year":"2013","journal-title":"Polymer"},{"key":"10.1016\/j.jconrel.2025.02.009_bb0340","first-page":"1","article-title":"Determination of paclitaxel solubility and stability in the presence of injectable excipients","author":"Sadeghi-Oroumiyeh","year":"2021","journal-title":"Pharm. Chem. J."},{"issue":"22","key":"10.1016\/j.jconrel.2025.02.009_bb0345","doi-asserted-by":"crossref","first-page":"10033","DOI":"10.1063\/1.477672","article-title":"Crystallization of a polymer on a surface","volume":"109","author":"Doye","year":"1998","journal-title":"J. Chem. Phys."},{"issue":"3","key":"10.1016\/j.jconrel.2025.02.009_bb0350","doi-asserted-by":"crossref","first-page":"417","DOI":"10.1021\/ma1023457","article-title":"Surface-induced polymer crystallization and the resultant structures and morphologies","volume":"44","author":"Li","year":"2011","journal-title":"Macromolecules"},{"key":"10.1016\/j.jconrel.2025.02.009_bb0355","doi-asserted-by":"crossref","first-page":"101","DOI":"10.1016\/j.polymertesting.2015.04.002","article-title":"Effects of cooling rates on crystallization behavior and melting characteristics of isotactic polypropylene as neat and in the TPVs EPDM\/PP and EOC\/PP","volume":"44","author":"Uthaipan","year":"2015","journal-title":"Polym. Test."},{"key":"10.1016\/j.jconrel.2025.02.009_bb0360","doi-asserted-by":"crossref","first-page":"1165","DOI":"10.1007\/s10973-013-3563-8","article-title":"Influence of processing conditions on polymer crystallization measured by fast scanning DSC","volume":"116","author":"Schawe","year":"2014","journal-title":"J. Therm. Anal. Calorim."},{"issue":"8","key":"10.1016\/j.jconrel.2025.02.009_bb0365","doi-asserted-by":"crossref","first-page":"3041","DOI":"10.1021\/acs.biomac.9b00618","article-title":"Like dissolves like? A comprehensive evaluation of partial solubility parameters to predict polymer\u2013drug compatibility in ultrahigh drug-loaded polymer micelles","volume":"20","author":"L\u00fcbtow","year":"2019","journal-title":"Biomacromolecules"},{"issue":"3","key":"10.1016\/j.jconrel.2025.02.009_bb0370","doi-asserted-by":"crossref","first-page":"39","DOI":"10.1208\/s12248-023-00807-4","article-title":"Plasma stability and plasma metabolite concentration\u2013time profiles of oligo (lactic acid) 8-paclitaxel prodrug loaded polymeric micelles","volume":"25","author":"Repp","year":"2023","journal-title":"AAPS J."},{"key":"10.1016\/j.jconrel.2025.02.009_bb0375","doi-asserted-by":"crossref","first-page":"186","DOI":"10.1016\/j.jconrel.2019.02.017","article-title":"Poly (ethylene glycol)-block-poly (d, l-lactic acid) micelles containing oligo (lactic acid) 8-paclitaxel prodrug: In Vivo conversion and antitumor efficacy","volume":"298","author":"Tam","year":"2019","journal-title":"J. Control. Release"},{"issue":"2","key":"10.1016\/j.jconrel.2025.02.009_bb0380","doi-asserted-by":"crossref","first-page":"279","DOI":"10.3390\/polym14020279","article-title":"Comparative investigation of cellular effects of polyethylene glycol (PEG) derivatives","volume":"14","author":"Pham Le Khanh","year":"2022","journal-title":"Polymers"},{"issue":"5","key":"10.1016\/j.jconrel.2025.02.009_bb0385","doi-asserted-by":"crossref","first-page":"693","DOI":"10.1177\/0885328218807675","article-title":"Poly (ethylene glycol) induces cell toxicity in melanoma cells by producing a hyperosmotic extracellular medium","volume":"33","author":"Postic","year":"2018","journal-title":"J. Biomater. Appl."}],"container-title":["Journal of Controlled Release"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0168365925001130?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0168365925001130?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,2,3]],"date-time":"2026-02-03T17:52:16Z","timestamp":1770141136000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0168365925001130"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,4]]},"references-count":77,"alternative-id":["S0168365925001130"],"URL":"https:\/\/doi.org\/10.1016\/j.jconrel.2025.02.009","relation":{},"ISSN":["0168-3659"],"issn-type":[{"value":"0168-3659","type":"print"}],"subject":[],"published":{"date-parts":[[2025,4]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Crystallization of supersaturated PEG-b-PLA for the production of drug-loaded polymeric micelles","name":"articletitle","label":"Article Title"},{"value":"Journal of Controlled Release","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.jconrel.2025.02.009","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2025 Elsevier B.V. All rights are reserved, including those for text and data mining, AI training, and similar technologies.","name":"copyright","label":"Copyright"}]}}