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Mater."},{"key":"10.1016\/j.jconrel.2025.114023_bb0315","article-title":"Peptide-drug conjugates repolarize glioblastoma-associated macrophages to resensitize chemo-immunotherapy of glioblastoma","volume":"11","author":"Li","year":"2025","journal-title":"Sci. Adv."},{"key":"10.1016\/j.jconrel.2025.114023_bb0320","doi-asserted-by":"crossref","DOI":"10.1016\/j.nantod.2022.101594","article-title":"Assembling synergistic peptide-drug conjugates for dual-targeted treatment of cancer metastasis","volume":"46","author":"Yu","year":"2022","journal-title":"Nano Today"},{"key":"10.1016\/j.jconrel.2025.114023_bb0325","doi-asserted-by":"crossref","first-page":"710","DOI":"10.1038\/s41578-023-00589-3","article-title":"In situ self-assembly for cancer therapy and imaging","volume":"8","author":"Kim","year":"2023","journal-title":"Nat. Rev. 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Soc."},{"key":"10.1016\/j.jconrel.2025.114023_bb0345","doi-asserted-by":"crossref","first-page":"6709","DOI":"10.1021\/jacs.2c02238","article-title":"Enzyme-responsive peptide thioesters for targeting golgi apparatus","volume":"144","author":"Tan","year":"2022","journal-title":"J. Am. Chem. Soc."},{"key":"10.1016\/j.jconrel.2025.114023_bb0350","doi-asserted-by":"crossref","first-page":"507","DOI":"10.1021\/cm403028b","article-title":"Supramolecular chemistry and self-assembly in organic materials design","volume":"26","author":"Stupp","year":"2014","journal-title":"Chem. Mater."},{"key":"10.1016\/j.jconrel.2025.114023_bb0355","doi-asserted-by":"crossref","first-page":"900","DOI":"10.1038\/s41563-020-0707-7","article-title":"Supramolecular-covalent hybrid polymers for light-activated mechanical actuation","volume":"19","author":"Li","year":"2020","journal-title":"Nat. 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Colloid Interface Sci."},{"key":"10.1016\/j.jconrel.2025.114023_bb0390","doi-asserted-by":"crossref","first-page":"10199","DOI":"10.1021\/acs.nanolett.1c02944","article-title":"Ordered packing of \u03b2-sheet nanofibrils into nanotubes: multi-hierarchical assembly of designed short peptides","volume":"21","author":"Ma","year":"2021","journal-title":"Nano Lett."},{"key":"10.1016\/j.jconrel.2025.114023_bb0395","doi-asserted-by":"crossref","first-page":"45821","DOI":"10.1021\/acsami.4c10653","article-title":"Self-assembly in living cells: bottom-up syntheses in natural factory","volume":"16","author":"Song","year":"2024","journal-title":"ACS Appl. Mater. Interfaces"},{"key":"10.1016\/j.jconrel.2025.114023_bb0400","doi-asserted-by":"crossref","first-page":"9312","DOI":"10.1021\/jacs.2c01025","article-title":"In situ self-sorting peptide assemblies in living cells for simultaneous organelle targeting","volume":"144","author":"Liu","year":"2022","journal-title":"J. Am. Chem. Soc."},{"key":"10.1016\/j.jconrel.2025.114023_bb0405","doi-asserted-by":"crossref","first-page":"4289","DOI":"10.1039\/D4TB00365A","article-title":"Self-assembly of peptides in living cells for disease theranostics","volume":"12","author":"Mo","year":"2024","journal-title":"J. Mater. Chem. B"},{"key":"10.1016\/j.jconrel.2025.114023_bb0410","doi-asserted-by":"crossref","first-page":"7965","DOI":"10.1021\/acs.nanolett.9b03136","article-title":"Proline isomerization-regulated tumor microenvironment-adaptable self-assembly of peptides for enhanced therapeutic efficacy","volume":"19","author":"Li","year":"2019","journal-title":"Nano Lett."},{"key":"10.1016\/j.jconrel.2025.114023_bb0415","doi-asserted-by":"crossref","first-page":"5730","DOI":"10.1021\/acs.nanolett.1c01469","article-title":"Supramolecular antagonists promote mitochondrial dysfunction","volume":"21","author":"Li","year":"2021","journal-title":"Nano Lett."},{"key":"10.1016\/j.jconrel.2025.114023_bb0420","doi-asserted-by":"crossref","first-page":"35","DOI":"10.1016\/j.jconrel.2021.10.026","article-title":"Adaptable peptide-based therapeutics modulating tumor microenvironment for combinatorial radio-immunotherapy","volume":"340","author":"Li","year":"2021","journal-title":"J. Control. Release"},{"key":"10.1016\/j.jconrel.2025.114023_bb0425","doi-asserted-by":"crossref","DOI":"10.1016\/j.nantod.2021.101198","article-title":"In situ oxidation-regulated self-assembly of peptides into transformable scaffolds for cascade therapy","volume":"38","author":"Song","year":"2021","journal-title":"Nano Today"},{"key":"10.1016\/j.jconrel.2025.114023_bb0430","doi-asserted-by":"crossref","first-page":"330","DOI":"10.1021\/jacs.3c09202","article-title":"Organelle-mediated dissipative self-assembly of peptides in living cells","volume":"146","author":"Wang","year":"2024","journal-title":"J. Am. Chem. Soc."},{"key":"10.1016\/j.jconrel.2025.114023_bb0435","doi-asserted-by":"crossref","first-page":"16445","DOI":"10.1002\/anie.202006290","article-title":"Enzymatically formed peptide assemblies sequestrate proteins and relocate inhibitors to selectively kill cancer cells","volume":"59","author":"He","year":"2020","journal-title":"Angew. Chem. Int. 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Release"},{"key":"10.1016\/j.jconrel.2025.114023_bb0470","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.canlet.2017.10.043","article-title":"The dual effects of a novel peptibody on angiogenesis inhibition and M2 macrophage polarization on sarcoma","volume":"416","author":"Zhu","year":"2018","journal-title":"Cancer Lett."},{"key":"10.1016\/j.jconrel.2025.114023_bb0475","doi-asserted-by":"crossref","first-page":"9537","DOI":"10.1039\/D0CC01089H","article-title":"Chlorotoxin-derived bicyclic peptides for targeted imaging of glioblastomas","volume":"56","author":"Li","year":"2020","journal-title":"Chem. Commun."},{"key":"10.1016\/j.jconrel.2025.114023_bb0480","doi-asserted-by":"crossref","first-page":"1418","DOI":"10.1038\/s43018-023-00626-8","article-title":"A designer peptide against the EAG2-Kv\u03b22 potassium channel targets the interaction of cancer cells and neurons to treat glioblastoma","volume":"4","author":"Dong","year":"2023","journal-title":"Nat. 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Mater. Interfaces"},{"key":"10.1016\/j.jconrel.2025.114023_bb0505","doi-asserted-by":"crossref","DOI":"10.1016\/j.cej.2024.150525","article-title":"A novel brain targeting MnOx-based MI-3 nanoplatform for immunogenic cell death initiated high-efficiency antitumor immunity against orthotopic glioblastoma","volume":"487","author":"Wang","year":"2024","journal-title":"Chem. Eng. J."},{"key":"10.1016\/j.jconrel.2025.114023_bb0510","doi-asserted-by":"crossref","first-page":"76","DOI":"10.1016\/j.jconrel.2019.06.021","article-title":"Nose-to-brain delivery of hyaluronate-FG loop peptide conjugate for non-invasive hypoxic-ischemic encephalopathy therapy","volume":"307","author":"Kim","year":"2019","journal-title":"J. Control. Release"},{"key":"10.1016\/j.jconrel.2025.114023_bb0515","doi-asserted-by":"crossref","first-page":"20210274","DOI":"10.1002\/EXP.20210274","article-title":"Brain co-delivery of first-line chemotherapy drug and epigenetic bromodomain inhibitor for multidimensional enhanced synergistic glioblastoma therapy","volume":"2","author":"Liu","year":"2022","journal-title":"Exploration"},{"key":"10.1016\/j.jconrel.2025.114023_bb0520","doi-asserted-by":"crossref","first-page":"6293","DOI":"10.1021\/acsnano.2c00320","article-title":"Brain-targeted codelivery of Bcl-2\/Bcl-xl and Mcl-1 inhibitors by biomimetic nanoparticles for orthotopic glioblastoma therapy","volume":"16","author":"He","year":"2022","journal-title":"ACS Nano"},{"key":"10.1016\/j.jconrel.2025.114023_bb0525","doi-asserted-by":"crossref","first-page":"16840","DOI":"10.1021\/acsnano.3c03724","article-title":"Dual-site f\u00f6rster resonance energy transfer route of upconversion nanoparticles-based brain-targeted nanotheranostic boosts the near-infrared phototherapy of glioma","volume":"17","author":"Wang","year":"2023","journal-title":"ACS Nano"},{"key":"10.1016\/j.jconrel.2025.114023_bb0530","doi-asserted-by":"crossref","first-page":"3445","DOI":"10.1021\/acs.nanolett.4c05470","article-title":"A brain-targeting NIR-II polymeric phototheranostic nanoplatform toward orthotopic drug-resistant glioblastoma","volume":"25","author":"Su","year":"2025","journal-title":"Nano Lett."},{"key":"10.1016\/j.jconrel.2025.114023_bb0535","doi-asserted-by":"crossref","DOI":"10.1016\/j.biomaterials.2022.121608","article-title":"Targeted liposomes for combined delivery of artesunate and temozolomide to resistant glioblastoma","volume":"287","author":"Ismail","year":"2022","journal-title":"Biomaterials"},{"key":"10.1016\/j.jconrel.2025.114023_bb0540","doi-asserted-by":"crossref","first-page":"1288","DOI":"10.1021\/acs.bioconjchem.5c00137","article-title":"Transferrin receptor-targeted aptamer-drug conjugate overcomes blood-brain barrier for potent glioblastoma therapy","volume":"36","author":"Zhao","year":"2025","journal-title":"Bioconjug. Chem."},{"key":"10.1016\/j.jconrel.2025.114023_bb0545","doi-asserted-by":"crossref","first-page":"2419395","DOI":"10.1002\/adfm.202419395","article-title":"Hierarchical targeting nanoplatform for NIR-II photoacoustic imaging and photo-activated synergistic immunotherapy of glioblastoma","author":"Zhang","year":"2025","journal-title":"Adv. Fun. Mater."},{"key":"10.1016\/j.jconrel.2025.114023_bb0550","doi-asserted-by":"crossref","first-page":"2921","DOI":"10.1021\/acs.biomac.1c00314","article-title":"Angiopep-2-modified carboxymethyl chitosan-based pH\/reduction dual-stimuli-responsive nanogels for enhanced targeting glioblastoma","volume":"22","author":"Song","year":"2021","journal-title":"Biomacromolecules"},{"key":"10.1016\/j.jconrel.2025.114023_bb0555","doi-asserted-by":"crossref","first-page":"6445","DOI":"10.1021\/acsnano.3c11958","article-title":"Cathepsin B-responsive programmed brain targeted delivery system for chemo-immunotherapy combination therapy of glioblastoma","volume":"18","author":"Jiang","year":"2024","journal-title":"ACS Nano"},{"key":"10.1016\/j.jconrel.2025.114023_bb0560","article-title":"Engineering and characterization of an artificial drug-carrying vesicles nanoplatform for enhanced specifically targeted therapy of glioblastoma","volume":"35","author":"Liu","year":"2023","journal-title":"Adv. Mater."},{"key":"10.1016\/j.jconrel.2025.114023_bb0565","doi-asserted-by":"crossref","first-page":"40391","DOI":"10.1021\/acsami.4c07850","article-title":"Targeted radionuclide therapy in glioblastoma","volume":"16","author":"Zhao","year":"2024","journal-title":"ACS Appl. Mater. Interfaces"},{"key":"10.1016\/j.jconrel.2025.114023_bb0570","doi-asserted-by":"crossref","first-page":"167","DOI":"10.1016\/j.jconrel.2023.08.011","article-title":"Spatiotemporally controlled Pseudomonas exotoxin transgene system combined with multifunctional nanoparticles for breast cancer antimetastatic therapy","volume":"367","author":"Cheng","year":"2024","journal-title":"J. Control. Release"},{"key":"10.1016\/j.jconrel.2025.114023_bb0575","doi-asserted-by":"crossref","first-page":"4775","DOI":"10.3390\/cancers15194775","article-title":"\u03b1V-integrin-dependent inhibition of glioblastoma cell migration, invasion and vasculogenic mimicry by the uPAcyclin decapeptide","volume":"15","author":"Franco","year":"2023","journal-title":"Cancers"},{"key":"10.1016\/j.jconrel.2025.114023_bb0580","doi-asserted-by":"crossref","first-page":"800","DOI":"10.1021\/acs.nanolett.4c05186","article-title":"Peptide-functionalized lipid nanoparticles for targeted systemic mRNA delivery to the brain","volume":"25","author":"Han","year":"2025","journal-title":"Nano Lett."},{"key":"10.1016\/j.jconrel.2025.114023_bb0585","doi-asserted-by":"crossref","first-page":"341","DOI":"10.1038\/nbt.1807","article-title":"Delivery of siRNA to the mouse brain by systemic injection of targeted exosomes","volume":"29","author":"Alvarez-Erviti","year":"2011","journal-title":"Nat. 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Mater."},{"key":"10.1016\/j.jconrel.2025.114023_bb0600","doi-asserted-by":"crossref","first-page":"3727","DOI":"10.1021\/acs.nanolett.4c00223","article-title":"X-ray activated nanoprodrug for visualization of cortical microvascular alterations and NIR-II image-guided chemo-radiotherapy of glioblastoma","volume":"24","author":"Su","year":"2024","journal-title":"Nano Lett."},{"key":"10.1016\/j.jconrel.2025.114023_bb0605","doi-asserted-by":"crossref","first-page":"1015","DOI":"10.1007\/s10555-024-10183-w","article-title":"Glioblastoma stem cell metabolism and immunity","volume":"43","author":"Hawly","year":"2024","journal-title":"Cancer Metastasis Rev."},{"key":"10.1016\/j.jconrel.2025.114023_bb0610","doi-asserted-by":"crossref","first-page":"12","DOI":"10.1016\/j.actbio.2017.05.054","article-title":"Enhanced targeting of invasive glioblastoma cells by peptide-functionalized gold nanorods in hydrogel-based 3D cultures","volume":"58","author":"Gon\u00e7alves","year":"2017","journal-title":"Acta Biomater."},{"key":"10.1016\/j.jconrel.2025.114023_bb0615","doi-asserted-by":"crossref","first-page":"832","DOI":"10.1016\/j.stem.2020.04.008","article-title":"The rational development of CD133-targeting immunotherapies for glioblastoma","volume":"26","author":"Vora","year":"2020","journal-title":"Cell Stem Cell"},{"key":"10.1016\/j.jconrel.2025.114023_bb0620","doi-asserted-by":"crossref","DOI":"10.1126\/scitranslmed.abn1128","article-title":"Intracavity generation of glioma stem cell-specific CAR macrophages primes locoregional immunity for postoperative glioblastoma therapy","volume":"14","author":"Chen","year":"2022","journal-title":"Sci. Transl. Med."},{"key":"10.1016\/j.jconrel.2025.114023_bb0625","doi-asserted-by":"crossref","DOI":"10.1126\/sciadv.abh2148","article-title":"PD-1 independent of PD-L1 ligation promotes glioblastoma growth through the NF\u03baB pathway","volume":"7","author":"Mirzaei","year":"2021","journal-title":"Sci. Adv."},{"key":"10.1016\/j.jconrel.2025.114023_bb0630","doi-asserted-by":"crossref","first-page":"2004973","DOI":"10.1002\/advs.202004973","article-title":"In vivo induction of regulatory T cells via CTLA-4 signaling peptide to control autoimmune encephalomyelitis and prevent disease relapse","volume":"8","author":"Kim","year":"2021","journal-title":"Adv. Sci."},{"key":"10.1016\/j.jconrel.2025.114023_bb0635","doi-asserted-by":"crossref","first-page":"13333","DOI":"10.1021\/acsnano.3c01428","article-title":"Nanoparticles hitchhike on monocytes for glioblastoma treatment after low-dose radiotherapy","volume":"17","author":"Kuang","year":"2023","journal-title":"ACS Nano"},{"key":"10.1016\/j.jconrel.2025.114023_bb0640","doi-asserted-by":"crossref","first-page":"1118","DOI":"10.1038\/s41467-024-44963-3","article-title":"Redox-responsive polymer micelles co-encapsulating immune checkpoint inhibitors and chemotherapeutic agents for glioblastoma therapy","volume":"15","author":"Zhang","year":"2024","journal-title":"Nat. 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