{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,11,5]],"date-time":"2026-11-05T04:57:19Z","timestamp":1793854639828,"version":"4.6.1"},"reference-count":61,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2025,11,1]],"date-time":"2025-11-01T00:00:00Z","timestamp":1761955200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2025,11,1]],"date-time":"2025-11-01T00:00:00Z","timestamp":1761955200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2025,11,1]],"date-time":"2025-11-01T00:00:00Z","timestamp":1761955200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2025,11,1]],"date-time":"2025-11-01T00:00:00Z","timestamp":1761955200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2025,11,1]],"date-time":"2025-11-01T00:00:00Z","timestamp":1761955200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2025,11,1]],"date-time":"2025-11-01T00:00:00Z","timestamp":1761955200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2025,11,1]],"date-time":"2025-11-01T00:00:00Z","timestamp":1761955200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"funder":[{"DOI":"10.13039\/501100007824","name":"Soochow University","doi-asserted-by":"publisher","award":["YXY2302014"],"award-info":[{"award-number":["YXY2302014"]}],"id":[{"id":"10.13039\/501100007824","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["52373298"],"award-info":[{"award-number":["52373298"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100012246","name":"Priority Academic Program Development of Jiangsu Higher Education Institutions","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100012246","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100012165","name":"Key Technologies Research and Development Program","doi-asserted-by":"publisher","award":["2024YFA1210300"],"award-info":[{"award-number":["2024YFA1210300"]}],"id":[{"id":"10.13039\/501100012165","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100012166","name":"National Key Research and Development Program of China","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100012166","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Journal of Controlled Release"],"published-print":{"date-parts":[[2025,11]]},"DOI":"10.1016\/j.jconrel.2025.114246","type":"journal-article","created":{"date-parts":[[2025,9,17]],"date-time":"2025-09-17T23:42:47Z","timestamp":1758152567000},"page":"114246","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":5,"special_numbering":"C","title":["Fluorinated albumin nanocages dually target CAFs and tumor cells to potentiate bladder cancer chemoimmunotherapy"],"prefix":"10.1016","volume":"387","author":[{"given":"Zhijun","family":"Miao","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anan","family":"Xu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gang","family":"Shen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Siyi","family":"Tang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jie","family":"Luo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jiajian","family":"Yang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zhe","family":"Chen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jinxian","family":"Pu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tao","family":"Yang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.jconrel.2025.114246_bb0005","doi-asserted-by":"crossref","first-page":"287","DOI":"10.1038\/s41571-023-00744-3","article-title":"Global trends in the epidemiology of bladder cancer: challenges for public health and clinical practice","volume":"20","author":"van Hoogstraten","year":"2023","journal-title":"Nat. Rev. Clin. Oncol."},{"key":"10.1016\/j.jconrel.2025.114246_bb0010","article-title":"Metastasis development in non-muscle-invasive bladder cancer","author":"Leyderman","year":"2024","journal-title":"Nat. Rev. Urol."},{"key":"10.1016\/j.jconrel.2025.114246_bb0015","doi-asserted-by":"crossref","first-page":"58","DOI":"10.1038\/s41572-023-00468-9","article-title":"Bladder cancer","volume":"9","author":"Dyrskj\u00f8t","year":"2023","journal-title":"Nat. Rev. Dis. Primers"},{"key":"10.1016\/j.jconrel.2025.114246_bb0020","doi-asserted-by":"crossref","first-page":"49","DOI":"10.1016\/j.eururo.2023.03.013","article-title":"European Association of Urology guidelines on upper urinary tract urothelial carcinoma: 2023 update","volume":"84","author":"Roupr\u00eat","year":"2023","journal-title":"Eur. Urol."},{"key":"10.1016\/j.jconrel.2025.114246_bb0025","doi-asserted-by":"crossref","first-page":"1712","DOI":"10.1016\/S0140-6736(22)01188-6","article-title":"Current best practice for bladder cancer: a narrative review of diagnostics and treatments","volume":"400","author":"Comp\u00e9rat","year":"2022","journal-title":"Lancet"},{"key":"10.1016\/j.jconrel.2025.114246_bb0030","doi-asserted-by":"crossref","DOI":"10.1136\/bmj-2023-076743","article-title":"Advances in diagnosis and treatment of bladder cancer","volume":"384","author":"Lopez-Beltran","year":"2024","journal-title":"BMJ"},{"key":"10.1016\/j.jconrel.2025.114246_bb0035","doi-asserted-by":"crossref","first-page":"2425","DOI":"10.1038\/s41467-021-22407-6","article-title":"Co-delivery of IOX1 and doxorubicin for antibody-independent cancer chemo-immunotherapy","volume":"12","author":"Liu","year":"2021","journal-title":"Nat. Commun."},{"key":"10.1016\/j.jconrel.2025.114246_bb0040","doi-asserted-by":"crossref","first-page":"4771","DOI":"10.1038\/s41467-023-40270-5","article-title":"Hyaluronic acid-bilirubin nanomedicine-based combination chemoimmunotherapy","volume":"14","author":"Lee","year":"2023","journal-title":"Nat. Commun."},{"key":"10.1016\/j.jconrel.2025.114246_bb0045","doi-asserted-by":"crossref","first-page":"8586","DOI":"10.1038\/s41467-024-53010-0","article-title":"Polymeric nanocarrier via metabolism regulation mediates immunogenic cell death with spatiotemporal orchestration for cancer immunotherapy","volume":"15","author":"Guo","year":"2024","journal-title":"Nat. Commun."},{"key":"10.1016\/j.jconrel.2025.114246_bb0050","doi-asserted-by":"crossref","first-page":"931","DOI":"10.1016\/S1470-2045(21)00152-2","article-title":"Pembrolizumab alone or combined with chemotherapy versus chemotherapy as first-line therapy for advanced urothelial carcinoma (KEYNOTE-361): a randomised, open-label, phase 3 trial","volume":"22","author":"Powles","year":"2021","journal-title":"Lancet Oncol."},{"key":"10.1016\/j.jconrel.2025.114246_bb0055","doi-asserted-by":"crossref","first-page":"9934","DOI":"10.1038\/s41467-024-54293-z","article-title":"Urease-powered nanomotor containing STING agonist for bladder cancer immunotherapy","volume":"15","author":"Choi","year":"2024","journal-title":"Nat. Commun."},{"key":"10.1016\/j.jconrel.2025.114246_bb0060","doi-asserted-by":"crossref","first-page":"554","DOI":"10.1038\/s41565-023-01577-y","article-title":"Urease-powered nanobots for radionuclide bladder cancer therapy","volume":"19","author":"Sim\u00f3","year":"2024","journal-title":"Nat. Nanotechnol."},{"key":"10.1016\/j.jconrel.2025.114246_bb0065","doi-asserted-by":"crossref","first-page":"1586","DOI":"10.1021\/acsnano.9b06689","article-title":"Fluorinated chitosan to enhance transmucosal delivery of sonosensitizer-conjugated catalase for sonodynamic bladder cancer treatment post-intravesical instillation","volume":"14","author":"Li","year":"2020","journal-title":"ACS Nano"},{"key":"10.1016\/j.jconrel.2025.114246_bb0070","doi-asserted-by":"crossref","DOI":"10.1016\/j.biomaterials.2022.121422","article-title":"Collagen-targeted tumor-specific transepithelial penetration enhancer mediated intravesical chemoimmunotherapy for non-muscle-invasive bladder cancer","volume":"283","author":"Li","year":"2022","journal-title":"Biomaterials"},{"key":"10.1016\/j.jconrel.2025.114246_bb0075","doi-asserted-by":"crossref","first-page":"544","DOI":"10.1038\/nature25501","article-title":"TGF\u03b2 attenuates tumour response to PD-L1 blockade by contributing to exclusion of T cells","volume":"554","author":"Mariathasan","year":"2018","journal-title":"Nature"},{"key":"10.1016\/j.jconrel.2025.114246_bb0080","doi-asserted-by":"crossref","first-page":"17","DOI":"10.1016\/j.immuni.2019.12.011","article-title":"Top 10 challenges in cancer immunotherapy","volume":"52","author":"Hegde","year":"2020","journal-title":"Immunity"},{"key":"10.1016\/j.jconrel.2025.114246_bb0085","doi-asserted-by":"crossref","first-page":"3503","DOI":"10.1038\/s41467-018-05992-x","article-title":"EMT- and stroma-related gene expression and resistance to PD-1 blockade in urothelial cancer","volume":"9","author":"Wang","year":"2018","journal-title":"Nat. Commun."},{"key":"10.1016\/j.jconrel.2025.114246_bb0090","doi-asserted-by":"crossref","first-page":"1487","DOI":"10.1038\/s41467-022-29026-9","article-title":"Cell death-induced immunogenicity enhances chemoimmunotherapeutic response by converting immune-excluded into T-cell inflamed bladder tumors","volume":"13","author":"Nikolos","year":"2022","journal-title":"Nat. Commun."},{"key":"10.1016\/j.jconrel.2025.114246_bb0095","doi-asserted-by":"crossref","first-page":"104","DOI":"10.1038\/s41568-020-00313-1","article-title":"Advances in bladder cancer biology and therapy","volume":"21","author":"Tran","year":"2021","journal-title":"Nat. Rev. Cancer"},{"key":"10.1016\/j.jconrel.2025.114246_bb0100","doi-asserted-by":"crossref","first-page":"1785","DOI":"10.1172\/JCI96313","article-title":"Spatially distinct tumor immune microenvironments stratify triple-negative breast cancers","volume":"129","author":"Gruosso","year":"2019","journal-title":"J. Clin. Invest."},{"key":"10.1016\/j.jconrel.2025.114246_bb0105","doi-asserted-by":"crossref","first-page":"622","DOI":"10.1038\/s41467-020-14425-7","article-title":"Dual-mechanism based CTLs infiltration enhancement initiated by nano-sapper potentiates immunotherapy against immune-excluded tumors","volume":"11","author":"Huang","year":"2020","journal-title":"Nat. Commun."},{"key":"10.1016\/j.jconrel.2025.114246_bb0110","doi-asserted-by":"crossref","first-page":"111","DOI":"10.1016\/j.canlet.2020.10.041","article-title":"Stromal reaction inhibitor and immune-checkpoint inhibitor combination therapy attenuates excluded-type colorectal cancer in a mouse model","volume":"498","author":"Yorita","year":"2021","journal-title":"Cancer Lett."},{"key":"10.1016\/j.jconrel.2025.114246_bb0115","doi-asserted-by":"crossref","first-page":"1243","DOI":"10.1002\/ijc.34345","article-title":"SPARC in cancer-associated fibroblasts is an independent poor prognostic factor in non-metastatic triple-negative breast cancer and exhibits pro-tumor activity","volume":"152","author":"Alcaraz","year":"2023","journal-title":"Int. J. Cancer"},{"key":"10.1016\/j.jconrel.2025.114246_bb0120","doi-asserted-by":"crossref","first-page":"6993","DOI":"10.1038\/ncomms7993","article-title":"Tumour-derived SPARC drives vascular permeability and extravasation through endothelial VCAM1 signalling to promote metastasis","volume":"6","author":"Tichet","year":"2015","journal-title":"Nat. Commun."},{"key":"10.1016\/j.jconrel.2025.114246_bb0125","doi-asserted-by":"crossref","DOI":"10.3389\/fmolb.2021.775743","article-title":"SPARC overexpression promotes liver cancer cell proliferation and tumor growth","volume":"8","author":"Gao","year":"2021","journal-title":"Front. Mol. Biosci."},{"key":"10.1016\/j.jconrel.2025.114246_bb0130","doi-asserted-by":"crossref","first-page":"596","DOI":"10.1016\/j.jconrel.2023.12.057","article-title":"Modulating the tumoral SPARC content to enhance albumin-based drug delivery for cancer therapy","volume":"366","author":"Zheng","year":"2024","journal-title":"J. Control. Release"},{"key":"10.1016\/j.jconrel.2025.114246_bb0135","doi-asserted-by":"crossref","DOI":"10.3389\/fphar.2024.1329636","article-title":"GP60 and SPARC as albumin receptors: key targeted sites for the delivery of antitumor drugs","volume":"15","author":"Ji","year":"2024","journal-title":"Front. Pharmacol."},{"key":"10.1016\/j.jconrel.2025.114246_bb0140","doi-asserted-by":"crossref","first-page":"820","DOI":"10.1038\/s41467-024-45158-6","article-title":"Non-invasive transdermal delivery of biomacromolecules with fluorocarbon-modified chitosan for melanoma immunotherapy and viral vaccines","volume":"15","author":"Zhu","year":"2024","journal-title":"Nat. Commun."},{"key":"10.1016\/j.jconrel.2025.114246_bb0145","article-title":"A pH-Activatable copper-biomineralized proenzyme for synergistic chemodynamic\/chemo-immunotherapy against aggressive cancers","volume":"35","author":"Li","year":"2023","journal-title":"Adv. Mater."},{"key":"10.1016\/j.jconrel.2025.114246_bb0150","doi-asserted-by":"crossref","first-page":"829","DOI":"10.1016\/j.jconrel.2024.07.001","article-title":"A bioinspired doxorubicin-carried albumin nanocage against aggressive cancer via systemic targeting of tumor and lymph node metastasis","volume":"372","author":"Iqbal","year":"2024","journal-title":"J. Control. Release"},{"key":"10.1016\/j.jconrel.2025.114246_bb0155","doi-asserted-by":"crossref","DOI":"10.1002\/adma.202206821","article-title":"Oral delivery of siRNA using fluorinated, small-sized nanocapsules toward anti-inflammation treatment","volume":"35","author":"Wei","year":"2023","journal-title":"Adv. Mater."},{"key":"10.1016\/j.jconrel.2025.114246_bb0160","article-title":"Fluorinated polyethylenimine to enable transmucosal delivery of photosensitizer-conjugated catalase for photodynamic therapy of orthotopic bladder tumors postintravesical instillation","volume":"29","author":"Li","year":"2019","journal-title":"Adv. Funct. Mater."},{"key":"10.1016\/j.jconrel.2025.114246_bb0165","doi-asserted-by":"crossref","first-page":"1377","DOI":"10.1038\/s41467-018-03779-8","article-title":"The fluorination effect of fluoroamphiphiles in cytosolic protein delivery","volume":"9","author":"Zhang","year":"2018","journal-title":"Nat. Commun."},{"key":"10.1016\/j.jconrel.2025.114246_bb0170","doi-asserted-by":"crossref","DOI":"10.1016\/j.ecoenv.2023.114940","article-title":"Fluoride disrupts intestinal epithelial tight junction integrity through intracellular calcium-mediated RhoA\/ROCK signaling and myosin light chain kinase","volume":"257","author":"Li","year":"2023","journal-title":"Ecotoxicol. Environ. Saf."},{"key":"10.1016\/j.jconrel.2025.114246_bb0175","article-title":"Fluorinated polymer mediated transmucosal peptide delivery for Intravesical instillation therapy of bladder cancer","volume":"15","author":"Li","year":"2019","journal-title":"Small"},{"key":"10.1016\/j.jconrel.2025.114246_bb0180","doi-asserted-by":"crossref","first-page":"366","DOI":"10.1016\/j.euo.2023.02.011","article-title":"Cancer-associated fibroblasts in bladder cancer: origin, biology, and therapeutic opportunities","volume":"6","author":"Caramelo","year":"2023","journal-title":"Eur. Urol. Oncol."},{"key":"10.1016\/j.jconrel.2025.114246_bb0185","doi-asserted-by":"crossref","first-page":"35","DOI":"10.1016\/j.cytogfr.2022.07.006","article-title":"Cancer-associated fibroblasts: vital suppressors of the immune response in the tumor microenvironment","volume":"67","author":"Xiang","year":"2022","journal-title":"Cytokine Growth Factor Rev."},{"key":"10.1016\/j.jconrel.2025.114246_bb0190","doi-asserted-by":"crossref","first-page":"375","DOI":"10.1038\/s41419-019-1581-6","article-title":"Cancer-associated fibroblasts promote cisplatin resistance in bladder cancer cells by increasing IGF-1\/ER\u03b2\/Bcl-2 signalling","volume":"10","author":"Long","year":"2019","journal-title":"Cell Death Dis."},{"key":"10.1016\/j.jconrel.2025.114246_bb0195","doi-asserted-by":"crossref","first-page":"10217","DOI":"10.1021\/jacs.3c14005","article-title":"Nanomedicine remodels tumor microenvironment for solid tumor immunotherapy","volume":"146","author":"Guo","year":"2024","journal-title":"J. Am. Chem. Soc."},{"key":"10.1016\/j.jconrel.2025.114246_bb0200","doi-asserted-by":"crossref","first-page":"218","DOI":"10.1038\/s41392-021-00641-0","article-title":"Signaling pathways in cancer-associated fibroblasts and targeted therapy for cancer","volume":"6","author":"Wu","year":"2021","journal-title":"Signal Transduct. Target. Ther."},{"key":"10.1016\/j.jconrel.2025.114246_bb0205","doi-asserted-by":"crossref","first-page":"81","DOI":"10.1016\/j.jconrel.2021.12.035","article-title":"SPARC-mediated long-term retention of nab-paclitaxel in pediatric sarcomas","volume":"342","author":"Pascual-Pasto","year":"2022","journal-title":"J. Control. Release"},{"key":"10.1016\/j.jconrel.2025.114246_bb0210","doi-asserted-by":"crossref","first-page":"365","DOI":"10.1016\/j.jconrel.2013.05.041","article-title":"Nab-paclitaxel mechanisms of action and delivery","volume":"170","author":"Yardley","year":"2013","journal-title":"J. Control. Release"},{"key":"10.1016\/j.jconrel.2025.114246_bb0215","doi-asserted-by":"crossref","first-page":"895","DOI":"10.1002\/ijc.32193","article-title":"In search of definitions: cancer-associated fibroblasts and their markers","volume":"146","author":"Nurmik","year":"2020","journal-title":"Int. J. Cancer"},{"key":"10.1016\/j.jconrel.2025.114246_bb0220","doi-asserted-by":"crossref","first-page":"1199","DOI":"10.1038\/s41467-022-28741-7","article-title":"Co-targeting of BAX and BCL-XL proteins broadly overcomes resistance to apoptosis in cancer","volume":"13","author":"Lopez","year":"2022","journal-title":"Nat. Commun."},{"key":"10.1016\/j.jconrel.2025.114246_bb0225","doi-asserted-by":"crossref","first-page":"99","DOI":"10.1038\/nrc.2015.17","article-title":"Thirty years of BCL-2: translating cell death discoveries into novel cancer therapies","volume":"16","author":"Delbridge","year":"2016","journal-title":"Nat. Rev. Cancer"},{"key":"10.1016\/j.jconrel.2025.114246_bb0230","doi-asserted-by":"crossref","first-page":"2264","DOI":"10.1039\/D0BM00112K","article-title":"Ultra pH-sensitive polymeric nanovesicles co-deliver doxorubicin and navitoclax for synergetic therapy of endometrial carcinoma","volume":"8","author":"Ding","year":"2020","journal-title":"Biomater. Sci."},{"key":"10.1016\/j.jconrel.2025.114246_bb0235","doi-asserted-by":"crossref","first-page":"13","DOI":"10.1038\/s41389-021-00302-5","article-title":"TGF-\u03b21-mediated transition of resident fibroblasts to cancer-associated fibroblasts promotes cancer metastasis in gastrointestinal stromal tumor","volume":"10","author":"Yoon","year":"2021","journal-title":"Oncogenesis"},{"key":"10.1016\/j.jconrel.2025.114246_bb0240","doi-asserted-by":"crossref","first-page":"104","DOI":"10.1186\/s12943-022-01569-x","article-title":"Targeting TGF-\u03b2 signal transduction for fibrosis and cancer therapy","volume":"21","author":"Peng","year":"2022","journal-title":"Mol. Cancer"},{"key":"10.1016\/j.jconrel.2025.114246_bb0245","doi-asserted-by":"crossref","first-page":"3322","DOI":"10.1038\/s41467-019-11235-4","article-title":"Bioinspired lipoproteins-mediated photothermia remodels tumor stroma to improve cancer cell accessibility of second nanoparticles","volume":"10","author":"Tan","year":"2019","journal-title":"Nat. Commun."},{"key":"10.1016\/j.jconrel.2025.114246_bb0250","article-title":"A tumor microenvironments-adapted polypeptide hydrogel\/nanogel composite boosts antitumor molecularly targeted inhibition and immunoactivation","volume":"34","author":"Li","year":"2022","journal-title":"Adv. Mater."},{"key":"10.1016\/j.jconrel.2025.114246_bb0255","doi-asserted-by":"crossref","first-page":"307","DOI":"10.1038\/s41419-024-06697-4","article-title":"Modulating extracellular matrix stiffness: a strategic approach to boost cancer immunotherapy","volume":"15","author":"Mai","year":"2024","journal-title":"Cell Death Dis."},{"key":"10.1016\/j.jconrel.2025.114246_bb0260","doi-asserted-by":"crossref","first-page":"897","DOI":"10.1158\/0008-5472.CAN-12-2130","article-title":"Therapeutic effects of deleting cancer-associated fibroblasts in cholangiocarcinoma","volume":"73","author":"Mertens","year":"2013","journal-title":"Cancer Res."},{"key":"10.1016\/j.jconrel.2025.114246_bb0265","doi-asserted-by":"crossref","first-page":"517","DOI":"10.1016\/j.molcel.2011.10.001","article-title":"A unified model of mammalian BCL-2 protein family interactions at the mitochondria","volume":"44","author":"Llambi","year":"2011","journal-title":"Mol. Cell"},{"key":"10.1016\/j.jconrel.2025.114246_bb0270","doi-asserted-by":"crossref","first-page":"123","DOI":"10.1016\/j.canlet.2011.12.025","article-title":"Use of the \u03b3-H2AX assay to monitor DNA damage and repair in translational cancer research","volume":"327","author":"Ivashkevich","year":"2012","journal-title":"Cancer Lett."},{"key":"10.1016\/j.jconrel.2025.114246_bb0275","doi-asserted-by":"crossref","first-page":"225","DOI":"10.1038\/s41568-024-00787-3","article-title":"Dendritic cell maturation in cancer","volume":"25","author":"Moon","year":"2025","journal-title":"Nat. Rev. Cancer"},{"key":"10.1016\/j.jconrel.2025.114246_bb0280","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1007\/s40242-024-4180-8","article-title":"Multidimensional role of amino acid metabolism in immune regulation: from molecular mechanisms to therapeutic strategies","volume":"41","author":"Qin","year":"2025","journal-title":"Chem. Res. Chin. Univ."},{"key":"10.1016\/j.jconrel.2025.114246_bb0285","doi-asserted-by":"crossref","first-page":"466","DOI":"10.1038\/s41587-025-02597-w","article-title":"Turn cold tumors hot by reprogramming the tumor microenvironment","volume":"43","author":"Yuan","year":"2025","journal-title":"Nat. Biotechnol."},{"key":"10.1016\/j.jconrel.2025.114246_bb0290","doi-asserted-by":"crossref","first-page":"2626","DOI":"10.3390\/cancers12092626","article-title":"Targeting myeloid-derived suppressor cells in cancer immunotherapy","volume":"12","author":"Wang","year":"2020","journal-title":"Cancers"},{"key":"10.1016\/j.jconrel.2025.114246_bb0295","doi-asserted-by":"crossref","first-page":"566","DOI":"10.1038\/s41423-020-00613-4","article-title":"Tumor-associated myeloid cells: diversity and therapeutic targeting","volume":"18","author":"Mantovani","year":"2021","journal-title":"Cell. Mol. Immunol."},{"key":"10.1016\/j.jconrel.2025.114246_bb0300","doi-asserted-by":"crossref","first-page":"780","DOI":"10.1038\/s41568-023-00615-0","article-title":"Stem-like exhausted and memory CD8+ T cells in cancer","volume":"23","author":"Gebhardt","year":"2023","journal-title":"Nat. Rev. Cancer"},{"key":"10.1016\/j.jconrel.2025.114246_bb0305","doi-asserted-by":"crossref","first-page":"159","DOI":"10.1186\/s12943-023-01860-5","article-title":"Define cancer-associated fibroblasts (CAFs) in the tumor microenvironment: new opportunities in cancer immunotherapy and advances in clinical trials","volume":"22","author":"Zhang","year":"2023","journal-title":"Mol. Cancer"}],"container-title":["Journal of Controlled Release"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0168365925008582?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0168365925008582?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,6,3]],"date-time":"2026-06-03T08:57:59Z","timestamp":1780477079000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0168365925008582"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,11]]},"references-count":61,"alternative-id":["S0168365925008582"],"URL":"https:\/\/doi.org\/10.1016\/j.jconrel.2025.114246","relation":{},"ISSN":["0168-3659"],"issn-type":[{"value":"0168-3659","type":"print"}],"subject":[],"published":{"date-parts":[[2025,11]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Fluorinated albumin nanocages dually target CAFs and tumor cells to potentiate bladder cancer chemoimmunotherapy","name":"articletitle","label":"Article Title"},{"value":"Journal of Controlled Release","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.jconrel.2025.114246","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2025 Elsevier B.V. All rights are reserved, including those for text and data mining, AI training, and similar technologies.","name":"copyright","label":"Copyright"}],"article-number":"114246"}}