{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,15]],"date-time":"2026-09-15T20:16:09Z","timestamp":1789503369273,"version":"build-2803163510"},"reference-count":66,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2026,3,1]],"date-time":"2026-03-01T00:00:00Z","timestamp":1772323200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2026,3,1]],"date-time":"2026-03-01T00:00:00Z","timestamp":1772323200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2026,3,1]],"date-time":"2026-03-01T00:00:00Z","timestamp":1772323200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2026,3,1]],"date-time":"2026-03-01T00:00:00Z","timestamp":1772323200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2026,3,1]],"date-time":"2026-03-01T00:00:00Z","timestamp":1772323200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2026,3,1]],"date-time":"2026-03-01T00:00:00Z","timestamp":1772323200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2026,3,1]],"date-time":"2026-03-01T00:00:00Z","timestamp":1772323200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"funder":[{"DOI":"10.13039\/501100001700","name":"Ministry of Education, Culture, Sports, Science and Technology","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100001700","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001691","name":"Japan Society for the Promotion of Science","doi-asserted-by":"publisher","award":["JPMJSP2127"],"award-info":[{"award-number":["JPMJSP2127"]}],"id":[{"id":"10.13039\/501100001691","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Journal of Controlled Release"],"published-print":{"date-parts":[[2026,3]]},"DOI":"10.1016\/j.jconrel.2025.114567","type":"journal-article","created":{"date-parts":[[2025,12,22]],"date-time":"2025-12-22T07:42:39Z","timestamp":1766389359000},"page":"114567","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":2,"special_numbering":"C","title":["Secreted protein acidic and rich in cysteine-guided biomimetic delivery of nano-antioxidants reverses muscle atrophy in a mouse model of sarcopenia"],"prefix":"10.1016","volume":"391","author":[{"given":"Gai","family":"Kanazawa","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hitoshi","family":"Maeda","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kengo","family":"Yasuda","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Isamu","family":"Noguchi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ayano","family":"Nishinoiri","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kazuaki","family":"Taguchi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shuhei","family":"Imoto","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kenji","family":"Tsukigawa","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Keishi","family":"Yamasaki","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mina","family":"Sakuragi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yu","family":"Ishima","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sadaharu","family":"Matsushita","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Teruya","family":"Nakamura","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Junji","family":"Saruwatari","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Masaki","family":"Otagiri","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hiroshi","family":"Watanabe","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Toru","family":"Maruyama","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.jconrel.2025.114567_bb0005","doi-asserted-by":"crossref","first-page":"04093","DOI":"10.7189\/jogh.12.04093","article-title":"Measurement and projection of the burden of disease attributable to population aging in 188 countries, 1990-2050: a population-based study","volume":"12","author":"Xi","year":"2022","journal-title":"J. Glob. Health"},{"key":"10.1016\/j.jconrel.2025.114567_bb0010","doi-asserted-by":"crossref","DOI":"10.3390\/nu12051293","article-title":"Sarcopenia: a contemporary health problem among older adult populations","volume":"12","author":"Papadopoulou","year":"2020","journal-title":"Nutrients"},{"key":"10.1016\/j.jconrel.2025.114567_bb0015","doi-asserted-by":"crossref","first-page":"156","DOI":"10.1016\/j.avsg.2019.03.019","article-title":"Impact of low activity of daily living on the prognosis of patients with critical limb ischemia and sarcopenia","volume":"61","author":"Shimazoe","year":"2019","journal-title":"Ann. Vasc. Surg."},{"key":"10.1016\/j.jconrel.2025.114567_bb0020","doi-asserted-by":"crossref","first-page":"16","DOI":"10.1093\/ageing\/afy169","article-title":"Sarcopenia: revised European consensus on definition and diagnosis","volume":"48","author":"Cruz-Jentoft","year":"2019","journal-title":"Age Ageing"},{"key":"10.1016\/j.jconrel.2025.114567_bb0025","doi-asserted-by":"crossref","first-page":"202","DOI":"10.1016\/j.freeradbiomed.2007.03.019","article-title":"Exercise and immobilization in aging animals: the involvement of oxidative stress and NF-kappaB activation","volume":"44","author":"Bar-Shai","year":"2008","journal-title":"Free Radic. Biol. Med."},{"issue":"2009","key":"10.1016\/j.jconrel.2025.114567_bb0030","first-page":"549","article-title":"A transient antioxidant stress response accompanies the onset of disuse atrophy in human skeletal muscle","volume":"107","author":"Dalla Libera","year":"1985","journal-title":"J. Appl. Physiol."},{"key":"10.1016\/j.jconrel.2025.114567_bb0035","doi-asserted-by":"crossref","first-page":"1832","DOI":"10.1002\/jcsm.12786","article-title":"Advanced oxidation protein products contribute to chronic kidney disease-induced muscle atrophy by inducing oxidative stress via CD36\/NADPH oxidase pathway","volume":"12","author":"Kato","year":"2021","journal-title":"J. Cachexia. Sarcopenia Muscle"},{"key":"10.1016\/j.jconrel.2025.114567_bb0040","doi-asserted-by":"crossref","first-page":"735","DOI":"10.1002\/jcsm.12202","article-title":"Potential therapeutic interventions for chronic kidney disease-associated sarcopenia via indoxyl sulfate-induced mitochondrial dysfunction","volume":"8","author":"Enoki","year":"2017","journal-title":"J. Cachexia. Sarcopenia Muscle"},{"key":"10.1016\/j.jconrel.2025.114567_bb0045","doi-asserted-by":"crossref","first-page":"536","DOI":"10.2174\/1389203720666190402100902","article-title":"Mitochondrial dysfunction in skeletal muscle pathologies","volume":"20","author":"Abrigo","year":"2019","journal-title":"Curr. Protein Pept. Sci."},{"key":"10.1016\/j.jconrel.2025.114567_bb0050","doi-asserted-by":"crossref","DOI":"10.3390\/ijms25052945","article-title":"Update on antioxidant therapy with Edaravone: expanding applications in neurodegenerative diseases","volume":"25","author":"Yamashita","year":"2024","journal-title":"Int. J. Mol. Sci."},{"key":"10.1016\/j.jconrel.2025.114567_bb0055","first-page":"2363","article-title":"Antioxidant drug approved for ALS","volume":"317","author":"Voelker","year":"2017","journal-title":"JAMA"},{"key":"10.1016\/j.jconrel.2025.114567_bb0060","doi-asserted-by":"crossref","DOI":"10.15252\/embj.2019103812","article-title":"Dysfunctional oxidative phosphorylation shunts branched-chain amino acid catabolism onto lipogenesis in skeletal muscle","volume":"39","author":"S\u00e1nchez-Gonz\u00e1lez","year":"2020","journal-title":"EMBO J."},{"key":"10.1016\/j.jconrel.2025.114567_bb0065","doi-asserted-by":"crossref","first-page":"1020","DOI":"10.1248\/cpb.58.1020","article-title":"1-(3\u2032-[125I]Iodophenyl)-3-methy-2-pyrazolin-5-one: preparation, solution stability, and biodistribution in normal mice","volume":"58","author":"Sano","year":"2010","journal-title":"Chem. Pharm. Bull. (Tokyo)"},{"key":"10.1016\/j.jconrel.2025.114567_bb0070","doi-asserted-by":"crossref","DOI":"10.3390\/biomedicines12092096","article-title":"Vascular impairment, muscle atrophy, and cognitive decline: critical age-related conditions","volume":"12","author":"de Lima","year":"2024","journal-title":"Biomedicines"},{"key":"10.1016\/j.jconrel.2025.114567_bb0075","doi-asserted-by":"crossref","DOI":"10.1111\/apha.13367","article-title":"Myokines in skeletal muscle physiology and metabolism: recent advances and future perspectives","volume":"228","author":"Das","year":"2020","journal-title":"Acta Physiol. (Oxford)"},{"key":"10.1016\/j.jconrel.2025.114567_bb0080","doi-asserted-by":"crossref","first-page":"3767","DOI":"10.2147\/DDDT.S88023","article-title":"Albumin-bound paclitaxel in solid tumors: clinical development and future directions","volume":"9","author":"Kundranda","year":"2015","journal-title":"Drug Des. Devel. Ther."},{"key":"10.1016\/j.jconrel.2025.114567_bb0085","doi-asserted-by":"crossref","first-page":"29","DOI":"10.1369\/jhc.2008.951954","article-title":"Secreted protein acidic and rich in cysteine (SPARC) in human skeletal muscle","volume":"57","author":"J\u00f8rgensen","year":"2009","journal-title":"J. Histochem. Cytochem."},{"key":"10.1016\/j.jconrel.2025.114567_bb0090","doi-asserted-by":"crossref","first-page":"9999","DOI":"10.1021\/acsnano.6b04268","article-title":"Blood-brain-barrier-penetrating albumin nanoparticles for biomimetic drug delivery via albumin-binding protein pathways for Antiglioma therapy","volume":"10","author":"Lin","year":"2016","journal-title":"ACS Nano"},{"key":"10.1016\/j.jconrel.2025.114567_bb0095","doi-asserted-by":"crossref","first-page":"81","DOI":"10.1016\/j.jconrel.2021.12.035","article-title":"SPARC-mediated long-term retention of nab-paclitaxel in pediatric sarcomas","volume":"342","author":"Pascual-Pasto","year":"2022","journal-title":"J. Control. Release"},{"key":"10.1016\/j.jconrel.2025.114567_bb0100","doi-asserted-by":"crossref","first-page":"569","DOI":"10.1023\/A:1015396825274","article-title":"Pharmaceutical strategies utilizing recombinant human serum albumin","volume":"19","author":"Chuang","year":"2002","journal-title":"Pharm. Res."},{"key":"10.1016\/j.jconrel.2025.114567_bb0105","doi-asserted-by":"crossref","first-page":"6945","DOI":"10.2147\/IJN.S467876","article-title":"Albumin nanoparticle-based drug delivery systems","volume":"19","author":"Qu","year":"2024","journal-title":"Int. J. Nanomedicine"},{"key":"10.1016\/j.jconrel.2025.114567_bb0110","doi-asserted-by":"crossref","first-page":"16668","DOI":"10.1021\/acsnano.3c02877","article-title":"Encapsulation of an antioxidant in redox-sensitive self-assembled albumin nanoparticles for the treatment of hepatitis","volume":"17","author":"Yasuda","year":"2023","journal-title":"ACS Nano"},{"key":"10.1016\/j.jconrel.2025.114567_bb0115","doi-asserted-by":"crossref","first-page":"173","DOI":"10.1016\/S0021-9258(19)81445-X","article-title":"Removal of fatty acids from serum albumin by charcoal treatment","volume":"242","author":"Chen","year":"1967","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.jconrel.2025.114567_bb0120","doi-asserted-by":"crossref","first-page":"17329","DOI":"10.1038\/s41598-018-35339-x","article-title":"A downstream molecule of 1,25-dihydroxyvitamin D3, alpha-1-acid glycoprotein, protects against mouse model of renal fibrosis","volume":"8","author":"Bi","year":"2018","journal-title":"Sci. Rep."},{"key":"10.1016\/j.jconrel.2025.114567_bb0125","doi-asserted-by":"crossref","first-page":"538","DOI":"10.1002\/jcsm.12709","article-title":"Mouse models of sarcopenia: classification and evaluation","volume":"12","author":"Xie","year":"2021","journal-title":"J. Cachexia. Sarcopenia Muscle"},{"key":"10.1016\/j.jconrel.2025.114567_bb0130","doi-asserted-by":"crossref","first-page":"1924","DOI":"10.1023\/B:PHAM.0000045248.03337.0e","article-title":"Functional analysis of recombinant human serum albumin domains for pharmaceutical applications","volume":"21","author":"Matsushita","year":"2004","journal-title":"Pharm. Res."},{"key":"10.1016\/j.jconrel.2025.114567_bb0135","doi-asserted-by":"crossref","first-page":"9627","DOI":"10.1016\/S0021-9258(19)83562-7","article-title":"Thioredoxin catalyzes the reduction of insulin disulfides by dithiothreitol and dihydrolipoamide","volume":"254","author":"Holmgren","year":"1979","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.jconrel.2025.114567_bb0140","doi-asserted-by":"crossref","first-page":"5473","DOI":"10.1038\/s41467-024-49781-1","article-title":"Variegated overexpression of chromosome 21 genes reveals molecular and immune subtypes of down syndrome","volume":"15","author":"Donovan","year":"2024","journal-title":"Nat. Commun."},{"key":"10.1016\/j.jconrel.2025.114567_bb0145","doi-asserted-by":"crossref","first-page":"77696","DOI":"10.18632\/oncotarget.12773","article-title":"Secreted protein acidic and rich in cysteine (SPARC) induces lipotoxicity in neuroblastoma by regulating transport of albumin complexed with fatty acids","volume":"7","author":"Chlenski","year":"2016","journal-title":"Oncotarget"},{"key":"10.1016\/j.jconrel.2025.114567_bb0150","doi-asserted-by":"crossref","first-page":"3131","DOI":"10.1074\/jbc.M205467200","article-title":"Protein-disulfide isomerase-mediated reduction of two disulfide bonds of HIV envelope glycoprotein 120 occurs post-CXCR4 binding and is required for fusion","volume":"278","author":"Barbouche","year":"2003","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.jconrel.2025.114567_bb0155","doi-asserted-by":"crossref","first-page":"406","DOI":"10.1016\/j.virol.2006.01.041","article-title":"Role of protein disulfide isomerase and other thiol-reactive proteins in HIV-1 envelope protein-mediated fusion","volume":"350","author":"Ou","year":"2006","journal-title":"Virology"},{"key":"10.1016\/j.jconrel.2025.114567_bb0160","doi-asserted-by":"crossref","first-page":"3592","DOI":"10.1016\/j.xphs.2019.07.002","article-title":"Maruyama, \u03b1(1)-acid glycoprotein has the potential to serve as a biomimetic drug delivery carrier for anticancer agents","volume":"108","author":"Matsusaka","year":"2019","journal-title":"J. Pharm. Sci."},{"key":"10.1016\/j.jconrel.2025.114567_bb0165","doi-asserted-by":"crossref","first-page":"611","DOI":"10.1002\/prot.20923","article-title":"Involvement of disulfide bonds and histidine 172 in a unique beta-sheet to alpha-helix transition of alpha 1-acid glycoprotein at the biomembrane interface","volume":"63","author":"Nishi","year":"2006","journal-title":"Proteins"},{"key":"10.1016\/j.jconrel.2025.114567_bb0170","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0099771","article-title":"Podocytes degrade endocytosed albumin primarily in lysosomes","volume":"9","author":"Carson","year":"2014","journal-title":"PLoS One"},{"key":"10.1016\/j.jconrel.2025.114567_bb0175","doi-asserted-by":"crossref","first-page":"1500","DOI":"10.1080\/15548627.2020.1771858","article-title":"Live imaging of intra-lysosome pH in cell lines and primary neuronal culture using a novel genetically encoded biosensor","volume":"17","author":"Ponsford","year":"2021","journal-title":"Autophagy"},{"key":"10.1016\/j.jconrel.2025.114567_bb0180","doi-asserted-by":"crossref","DOI":"10.3390\/ijms251910766","article-title":"Advancements in drug delivery systems for the treatment of sarcopenia: an updated overview","volume":"25","author":"Najm","year":"2024","journal-title":"Int. J. Mol. Sci."},{"key":"10.1016\/j.jconrel.2025.114567_bb0185","doi-asserted-by":"crossref","first-page":"183","DOI":"10.1007\/s00223-014-9915-y","article-title":"Skeletal muscle: a brief review of structure and function","volume":"96","author":"Frontera","year":"2015","journal-title":"Calcif. Tissue Int."},{"key":"10.1016\/j.jconrel.2025.114567_bb0190","doi-asserted-by":"crossref","first-page":"375","DOI":"10.1083\/jcb.139.2.375","article-title":"Animal models for muscular dystrophy show different patterns of sarcolemmal disruption","volume":"139","author":"Straub","year":"1997","journal-title":"J. Cell Biol."},{"key":"10.1016\/j.jconrel.2025.114567_bb0195","first-page":"6387","article-title":"A new concept for macromolecular therapeutics in cancer chemotherapy: mechanism of tumoritropic accumulation of proteins and the antitumor agent smancs","volume":"46","author":"Matsumura","year":"1986","journal-title":"Cancer Res."},{"key":"10.1016\/j.jconrel.2025.114567_bb0200","doi-asserted-by":"crossref","first-page":"41","DOI":"10.1517\/17425247.2015.955847","article-title":"Advances in an active and passive targeting to tumor and adipose tissues","volume":"12","author":"Sakurai","year":"2015","journal-title":"Expert Opin. Drug Deliv."},{"key":"10.1016\/j.jconrel.2025.114567_bb0205","doi-asserted-by":"crossref","first-page":"1253","DOI":"10.1039\/C5BM00113G","article-title":"Anti-angiogenic nanotherapy via active targeting systems to tumors and adipose tissue vasculature","volume":"3","author":"Sakurai","year":"2015","journal-title":"Biomater. Sci."},{"key":"10.1016\/j.jconrel.2025.114567_bb0210","doi-asserted-by":"crossref","first-page":"H326","DOI":"10.1152\/ajpheart.00635.2015","article-title":"Advances and challenges in skeletal muscle angiogenesis","volume":"310","author":"Olfert","year":"2016","journal-title":"Am. J. Physiol. Heart Circ. Physiol."},{"key":"10.1016\/j.jconrel.2025.114567_bb0215","doi-asserted-by":"crossref","first-page":"947","DOI":"10.2165\/00007256-200838110-00005","article-title":"The inflammatory response to skeletal muscle injury: illuminating complexities","volume":"38","author":"Smith","year":"2008","journal-title":"Sports Med."},{"key":"10.1016\/j.jconrel.2025.114567_bb0220","doi-asserted-by":"crossref","DOI":"10.1111\/micc.12879","article-title":"Lymphatic capillarization in different Fiber types of rat skeletal muscles with growth and age","volume":"31","author":"Taketa","year":"2024","journal-title":"Microcirculation"},{"key":"10.1016\/j.jconrel.2025.114567_bb0225","doi-asserted-by":"crossref","DOI":"10.3389\/fphar.2024.1329636","article-title":"GP60 and SPARC as albumin receptors: key targeted sites for the delivery of antitumor drugs","volume":"15","author":"Ji","year":"2024","journal-title":"Front. Pharmacol."},{"key":"10.1016\/j.jconrel.2025.114567_bb0230","doi-asserted-by":"crossref","first-page":"235","DOI":"10.1038\/nm.4256","article-title":"Direct evidence for cancer-cell-autonomous extracellular protein catabolism in pancreatic tumors","volume":"23","author":"Davidson","year":"2017","journal-title":"Nat. Med."},{"key":"10.1016\/j.jconrel.2025.114567_bb0235","doi-asserted-by":"crossref","first-page":"41","DOI":"10.1186\/s12986-024-00820-0","article-title":"Amino acids regulating skeletal muscle metabolism: mechanisms of action, physical training dosage recommendations and adverse effects","volume":"21","author":"Li","year":"2024","journal-title":"Nutr. Metab. (Lond.)"},{"key":"10.1016\/j.jconrel.2025.114567_bb0240","doi-asserted-by":"crossref","DOI":"10.3390\/nu9101047","article-title":"Is branched-chain amino acids supplementation an efficient nutritional strategy to alleviate skeletal muscle damage? A systematic review","volume":"9","author":"Four\u00e9","year":"2017","journal-title":"Nutrients"},{"key":"10.1016\/j.jconrel.2025.114567_bb0245","doi-asserted-by":"crossref","first-page":"23","DOI":"10.1152\/physrev.00043.2011","article-title":"Satellite cells and the muscle stem cell niche","volume":"93","author":"Yin","year":"2013","journal-title":"Physiol. Rev."},{"key":"10.1016\/j.jconrel.2025.114567_bb0250","doi-asserted-by":"crossref","first-page":"2064","DOI":"10.1126\/science.1114758","article-title":"Direct isolation of satellite cells for skeletal muscle regeneration","volume":"309","author":"Montarras","year":"2005","journal-title":"Science"},{"key":"10.1016\/j.jconrel.2025.114567_bb0255","doi-asserted-by":"crossref","first-page":"513","DOI":"10.1007\/s10561-017-9614-9","article-title":"Isolation, culture and biological characteristics of multipotent porcine skeletal muscle satellite cells","volume":"18","author":"Yang","year":"2017","journal-title":"Cell Tissue Bank."},{"key":"10.1016\/j.jconrel.2025.114567_bb0260","doi-asserted-by":"crossref","first-page":"175","DOI":"10.1111\/acel.12168","article-title":"Secreted protein acidic and rich in cysteine internalization and its age-related alterations in skeletal muscle progenitor cells","volume":"13","author":"Nakamura","year":"2014","journal-title":"Aging Cell"},{"key":"10.1016\/j.jconrel.2025.114567_bb0265","doi-asserted-by":"crossref","first-page":"6177","DOI":"10.1074\/jbc.M111.292649","article-title":"Role of integrin-\u03b23 protein in macrophage polarization and regeneration of injured muscle","volume":"287","author":"Zhang","year":"2012","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.jconrel.2025.114567_bb0270","doi-asserted-by":"crossref","DOI":"10.3390\/ijms26062802","article-title":"Mechanotransduction and skeletal muscle atrophy: the interplay between focal adhesions and oxidative stress","volume":"26","author":"Kamal","year":"2025","journal-title":"Int. J. Mol. Sci."},{"key":"10.1016\/j.jconrel.2025.114567_bb0275","first-page":"22","article-title":"Lysosomes and lysosomal cathepsins in cell death","volume":"2012","author":"Repnik","year":"1824","journal-title":"Biochim. Biophys. Acta"},{"key":"10.1016\/j.jconrel.2025.114567_bb0280","doi-asserted-by":"crossref","first-page":"775","DOI":"10.1042\/bj2180775","article-title":"Role of thiols, pH and cathepsin D in the lysosomal catabolism of serum albumin","volume":"218","author":"Mego","year":"1984","journal-title":"Biochem. J."},{"key":"10.1016\/j.jconrel.2025.114567_bb0285","doi-asserted-by":"crossref","first-page":"3042","DOI":"10.1074\/jbc.275.5.3042","article-title":"Conformational transitions of the three recombinant domains of human serum albumin depending on pH","volume":"275","author":"Dockal","year":"2000","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.jconrel.2025.114567_bb0290","article-title":"Exerkines and sarcopenia: unveiling the mechanism behind exercise-induced mitochondrial homeostasis","volume":"15","author":"Wang","year":"2025","journal-title":"Metabolites"},{"key":"10.1016\/j.jconrel.2025.114567_bb0295","doi-asserted-by":"crossref","first-page":"1535","DOI":"10.1007\/s11010-024-05120-y","article-title":"Therapeutic applications and challenges in myostatin inhibition for enhanced skeletal muscle mass and functions","volume":"480","author":"Wetzlich","year":"2025","journal-title":"Mol. Cell. Biochem."},{"key":"10.1016\/j.jconrel.2025.114567_bb0300","doi-asserted-by":"crossref","first-page":"3633","DOI":"10.1002\/jbm.a.35481","article-title":"Poly(3,4-ethylenedioxythiophene) nanoparticle and poly(\u025b-caprolactone) electrospun scaffold characterization for skeletal muscle regeneration","volume":"103","author":"McKeon-Fischer","year":"2015","journal-title":"J. Biomed. Mater. Res. A"},{"key":"10.1016\/j.jconrel.2025.114567_bb0305","doi-asserted-by":"crossref","first-page":"1016","DOI":"10.3389\/fphar.2020.01016","article-title":"Advance in drug delivery for ageing skeletal muscle","volume":"11","author":"Li","year":"2020","journal-title":"Front. Pharmacol."},{"key":"10.1016\/j.jconrel.2025.114567_bb0310","doi-asserted-by":"crossref","first-page":"303","DOI":"10.1186\/s12951-023-01994-0","article-title":"Nanoparticles systemically biodistribute to regenerating skeletal muscle in DMD","volume":"21","author":"Hicks","year":"2023","journal-title":"J. Nanobiotechnol."},{"key":"10.1016\/j.jconrel.2025.114567_bb0315","doi-asserted-by":"crossref","first-page":"808","DOI":"10.1016\/0091-6749(85)90753-5","article-title":"An investigation of possible immunologic reactions to human serum albumin used as a stabilizer in allergy extracts","volume":"76","author":"Brown","year":"1985","journal-title":"J. Allergy Clin. Immunol."},{"key":"10.1016\/j.jconrel.2025.114567_bb0320","doi-asserted-by":"crossref","first-page":"1977","DOI":"10.1111\/jth.12409","article-title":"Safety and pharmacokinetics of a recombinant fusion protein linking coagulation factor VIIa with albumin in healthy volunteers","volume":"11","author":"Golor","year":"2013","journal-title":"J. Thromb. Haemost."},{"key":"10.1016\/j.jconrel.2025.114567_bb0325","doi-asserted-by":"crossref","first-page":"35","DOI":"10.1186\/s40580-018-0168-8","article-title":"Therapeutic nanoplatforms and delivery strategies for neurological disorders","volume":"5","author":"Kang","year":"2018","journal-title":"Nano Converg."},{"key":"10.1016\/j.jconrel.2025.114567_bb0330","doi-asserted-by":"crossref","DOI":"10.1016\/j.lfs.2024.122990","article-title":"Increased SPARC in brain microvessels of Ob\/Ob mice accelerates molecular transport into the brain accompany with albumin","volume":"355","author":"Tsurudome","year":"2024","journal-title":"Life Sci."}],"container-title":["Journal of Controlled Release"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0168365925011812?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0168365925011812?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,6,18]],"date-time":"2026-06-18T08:39:47Z","timestamp":1781771987000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0168365925011812"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,3]]},"references-count":66,"alternative-id":["S0168365925011812"],"URL":"https:\/\/doi.org\/10.1016\/j.jconrel.2025.114567","relation":{},"ISSN":["0168-3659"],"issn-type":[{"value":"0168-3659","type":"print"}],"subject":[],"published":{"date-parts":[[2026,3]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Secreted protein acidic and rich in cysteine-guided biomimetic delivery of nano-antioxidants reverses muscle atrophy in a mouse model of sarcopenia","name":"articletitle","label":"Article Title"},{"value":"Journal of Controlled Release","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.jconrel.2025.114567","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2025 Published by Elsevier B.V.","name":"copyright","label":"Copyright"}],"article-number":"114567"}}