{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,24]],"date-time":"2026-08-24T14:34:56Z","timestamp":1787582096207,"version":"build-2736575974"},"reference-count":255,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2026,8,1]],"date-time":"2026-08-01T00:00:00Z","timestamp":1785542400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2026,8,1]],"date-time":"2026-08-01T00:00:00Z","timestamp":1785542400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2026,8,1]],"date-time":"2026-08-01T00:00:00Z","timestamp":1785542400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2026,8,1]],"date-time":"2026-08-01T00:00:00Z","timestamp":1785542400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2026,8,1]],"date-time":"2026-08-01T00:00:00Z","timestamp":1785542400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2026,8,1]],"date-time":"2026-08-01T00:00:00Z","timestamp":1785542400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2026,8,1]],"date-time":"2026-08-01T00:00:00Z","timestamp":1785542400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"funder":[{"DOI":"10.13039\/501100007129","name":"Natural Science Foundation of Shandong Province","doi-asserted-by":"publisher","award":["ZR2024YQ055"],"award-info":[{"award-number":["ZR2024YQ055"]}],"id":[{"id":"10.13039\/501100007129","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100014103","name":"Key Technology Research and Development Program of Shandong Province","doi-asserted-by":"publisher","award":["2025CXPT113"],"award-info":[{"award-number":["2025CXPT113"]}],"id":[{"id":"10.13039\/100014103","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100014103","name":"Key Technology Research and Development Program of Shandong Province","doi-asserted-by":"publisher","award":["2025CXPT042"],"award-info":[{"award-number":["2025CXPT042"]}],"id":[{"id":"10.13039\/100014103","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100014103","name":"Key Technology Research and Development Program of Shandong Province","doi-asserted-by":"publisher","award":["2024CXPT090"],"award-info":[{"award-number":["2024CXPT090"]}],"id":[{"id":"10.13039\/100014103","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Journal of Controlled Release"],"published-print":{"date-parts":[[2026,8]]},"DOI":"10.1016\/j.jconrel.2026.115067","type":"journal-article","created":{"date-parts":[[2026,6,3]],"date-time":"2026-06-03T08:09:49Z","timestamp":1780474189000},"page":"115067","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":0,"special_numbering":"C","title":["Oxygen-releasing biomaterials for bone tissue regeneration"],"prefix":"10.1016","volume":"396","author":[{"given":"Zhengyu","family":"Zhang","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ying","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xiaoru","family":"Yang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jianhua","family":"Li","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.jconrel.2026.115067_bb0005","first-page":"477","article-title":"Bone microenvironment regulative hydrogels with ROS scavenging and prolonged oxygen-generating for enhancing bone repair","volume":"24","author":"Sun","year":"2023","journal-title":"Bioact. Mater."},{"issue":"4","key":"10.1016\/j.jconrel.2026.115067_bb0010","doi-asserted-by":"crossref","DOI":"10.1002\/bmm2.12046","article-title":"Advanced strategies of scaffolds design for bone regeneration","volume":"1","author":"Song","year":"2023","journal-title":"BMEMat"},{"issue":"7","key":"10.1016\/j.jconrel.2026.115067_bb0015","doi-asserted-by":"crossref","first-page":"399","DOI":"10.1038\/s41574-024-00969-x","article-title":"Metabolic regulation of skeletal cell fate and function","volume":"20","author":"Stegen","year":"2024","journal-title":"Nat. Rev. Endocrinol."},{"key":"10.1016\/j.jconrel.2026.115067_bb0020","article-title":"Optimizing biophysical properties of cellular niches to enhance stem cell-derived extracellular vesicle function in musculoskeletal regeneration","author":"Xu","year":"2025","journal-title":"BMEMat"},{"issue":"4","key":"10.1016\/j.jconrel.2026.115067_bb0025","article-title":"Revolutionizing bone regeneration: vascularized bone tissue engineering with advanced 3D printing technology","volume":"6","author":"Fan","year":"2025","journal-title":"Aggregate"},{"key":"10.1016\/j.jconrel.2026.115067_bb0030","doi-asserted-by":"crossref","first-page":"61","DOI":"10.1016\/j.actbio.2024.03.032","article-title":"Microfluidic strategies for engineering oxygen-releasing biomaterials","volume":"179","author":"Zhu","year":"2024","journal-title":"Acta Biomater."},{"issue":"6","key":"10.1016\/j.jconrel.2026.115067_bb0035","doi-asserted-by":"crossref","DOI":"10.1002\/adhm.202002058","article-title":"Discrepancies on the role of oxygen gradient and culture condition on mesenchymal stem cell fate","volume":"10","author":"Samal","year":"2021","journal-title":"Adv. Healthc. Mater."},{"issue":"19","key":"10.1016\/j.jconrel.2026.115067_bb0040","doi-asserted-by":"crossref","DOI":"10.1002\/adfm.202009432","article-title":"Recent advances in design of functional biocompatible hydrogels for bone tissue engineering","volume":"31","author":"Xue","year":"2021","journal-title":"Adv. Funct. Mater."},{"issue":"6","key":"10.1016\/j.jconrel.2026.115067_bb0045","doi-asserted-by":"crossref","first-page":"1248","DOI":"10.1111\/jre.13180","article-title":"Hypoxia dissociates HDAC6\/FOXO1 complex and aggregates them into nucleus to regulate autophagy and osteogenic differentiation","volume":"58","year":"2023","journal-title":"J. Periodontal Res."},{"issue":"11","key":"10.1016\/j.jconrel.2026.115067_bb0050","doi-asserted-by":"crossref","first-page":"696","DOI":"10.1038\/s41580-020-00279-w","article-title":"Mechanisms of bone development and repair","volume":"21","author":"Salhotra","year":"2020","journal-title":"Nat. Rev. Mol. Cell Biol."},{"issue":"1","key":"10.1016\/j.jconrel.2026.115067_bb0055","doi-asserted-by":"crossref","DOI":"10.1038\/s41413-019-0054-y","article-title":"Controlling hypoxia-inducible factor-2\u03b1 is critical for maintaining bone homeostasis in mice","volume":"7","author":"Lee","year":"2019","journal-title":"Bone Res."},{"issue":"1","key":"10.1016\/j.jconrel.2026.115067_bb0060","doi-asserted-by":"crossref","first-page":"71","DOI":"10.1038\/s41421-024-00689-6","article-title":"Cell signaling and transcriptional regulation of osteoblast lineage commitment, differentiation, bone formation, and homeostasis","volume":"10","author":"Zhu","year":"2024","journal-title":"Cell Discov."},{"issue":"1","key":"10.1016\/j.jconrel.2026.115067_bb0065","article-title":"Magnetic hydroxyapatite nanobelt-stem cell hybrid spheroids for remotely patterning bone tissues","volume":"2","author":"Hao","year":"2024","journal-title":"BMEMat"},{"key":"10.1016\/j.jconrel.2026.115067_bb0070","doi-asserted-by":"crossref","first-page":"11","DOI":"10.1186\/1471-2121-11-11","article-title":"Low physiologic oxygen tensions reduce proliferation and differentiation of human multipotent mesenchymal stromal cells","volume":"11","author":"Holzwarth","year":"2010","journal-title":"BMC Cell Biol."},{"issue":"7656","key":"10.1016\/j.jconrel.2026.115067_bb0075","doi-asserted-by":"crossref","first-page":"124","DOI":"10.1038\/nature22389","article-title":"Electric-field control of tri-state phase transformation with a selective dual-ion switch","volume":"546","author":"Lu","year":"2017","journal-title":"Nature"},{"issue":"6","key":"10.1016\/j.jconrel.2026.115067_bb0080","doi-asserted-by":"crossref","first-page":"583","DOI":"10.1080\/03008207.2019.1611792","article-title":"Hypoxia reduces the osteogenic differentiation of peripheral blood mesenchymal stem cells by upregulating Notch-1 expression","volume":"60","author":"Yang","year":"2019","journal-title":"Connect. Tissue Res."},{"issue":"9","key":"10.1016\/j.jconrel.2026.115067_bb0085","doi-asserted-by":"crossref","first-page":"1389","DOI":"10.3390\/ijms17091389","article-title":"Hypoxia suppresses spontaneous mineralization and osteogenic differentiation of mesenchymal stem cells via IGFBP3 up-regulation","volume":"17","author":"Kim","year":"2016","journal-title":"Int. J. Mol. Sci."},{"issue":"12","key":"10.1016\/j.jconrel.2026.115067_bb0090","doi-asserted-by":"crossref","first-page":"2779","DOI":"10.1002\/stem.1441","article-title":"Inhibitory effects of hypoxia on metabolic switch and osteogenic differentiation of human mesenchymal stem cells","volume":"31","author":"Hsu","year":"2013","journal-title":"Stem Cells (Dayt. Ohio)"},{"issue":"4","key":"10.1016\/j.jconrel.2026.115067_bb0095","first-page":"C1139","article-title":"Effect of reduced oxygen tension on chondrogenesis and osteogenesis in adipose-derived mesenchymal cells","volume":"290","author":"Malladi","year":"2006","journal-title":"Am. J. Phys. Cell Phys."},{"issue":"10","key":"10.1016\/j.jconrel.2026.115067_bb0100","doi-asserted-by":"crossref","first-page":"2804","DOI":"10.3390\/biomedicines11102804","article-title":"Extracellular vesicles derived from osteogenic-differentiated human bone marrow-derived mesenchymal cells rescue osteogenic ability of bone marrow-derived mesenchymal cells impaired by hypoxia","volume":"11","author":"Wang","year":"2023","journal-title":"Biomedicines"},{"issue":"1","key":"10.1016\/j.jconrel.2026.115067_bb0105","doi-asserted-by":"crossref","first-page":"56","DOI":"10.1111\/nyas.14483","article-title":"CircCDK8 regulates osteogenic differentiation and apoptosis of PDLSCs by inducing ER stress\/autophagy during hypoxia","volume":"1485","author":"Zheng","year":"2021","journal-title":"Ann. N. Y. Acad. Sci."},{"issue":"2","key":"10.1016\/j.jconrel.2026.115067_bb0110","doi-asserted-by":"crossref","DOI":"10.1016\/j.yexcr.2022.113324","article-title":"HIF-1\u03b1 drives the transcription of NOG to inhibit osteogenic differentiation of periodontal ligament stem cells in response to hypoxia","volume":"419","author":"Pan","year":"2022","journal-title":"Exp. Cell Res."},{"issue":"1","key":"10.1016\/j.jconrel.2026.115067_bb0115","doi-asserted-by":"crossref","first-page":"103","DOI":"10.1016\/j.abb.2010.07.021","article-title":"Acidosis, hypoxia and bone","volume":"503","author":"Arnett","year":"2010","journal-title":"Arch. Biochem. Biophys."},{"issue":"7","key":"10.1016\/j.jconrel.2026.115067_bb0120","doi-asserted-by":"crossref","first-page":"332","DOI":"10.1016\/j.tem.2009.04.001","article-title":"Mitochondrial generation of free radicals and hypoxic signaling","volume":"20","author":"Poyton","year":"2009","journal-title":"Trends Endocrinol. Metab."},{"issue":"1","key":"10.1016\/j.jconrel.2026.115067_bb0125","doi-asserted-by":"crossref","first-page":"44","DOI":"10.1016\/j.biocel.2006.07.001","article-title":"Free radicals and antioxidants in normal physiological functions and human disease","volume":"39","author":"Valko","year":"2007","journal-title":"Int. J. Biochem. Cell Biol."},{"issue":"20","key":"10.1016\/j.jconrel.2026.115067_bb0130","doi-asserted-by":"crossref","first-page":"11715","DOI":"10.1073\/pnas.95.20.11715","article-title":"Mitochondrial reactive oxygen species trigger hypoxia-induced transcription","volume":"95","author":"Chandel","year":"1998","journal-title":"Proc. Natl. Acad. Sci."},{"issue":"4","key":"10.1016\/j.jconrel.2026.115067_bb0135","first-page":"579","article-title":"Role of oxidative stress in hypoxia pre-conditioning of cells transplanted to the myocardium: a molecular imaging study","volume":"52","author":"Aly","year":"2011","journal-title":"J. Cardiovasc. Surg."},{"issue":"6","key":"10.1016\/j.jconrel.2026.115067_bb0140","doi-asserted-by":"crossref","first-page":"527","DOI":"10.1111\/cpr.12147","article-title":"Icariin attenuates hypoxia-induced oxidative stress and apoptosis in osteoblasts and preserves their osteogenic differentiation potential in vitro","volume":"47","author":"Ma","year":"2014","journal-title":"Cell Prolif."},{"issue":"6","key":"10.1016\/j.jconrel.2026.115067_bb0145","doi-asserted-by":"crossref","first-page":"1088","DOI":"10.1161\/ATVBAHA.119.312509","article-title":"Hypoxia triggers osteochondrogenic differentiation of vascular smooth muscle cells in an HIF-1 (hypoxia-inducible factor 1)-dependent and reactive oxygen species-dependent manner","volume":"39","author":"Balogh","year":"2019","journal-title":"Arterioscler. Thromb. Vasc. Biol."},{"issue":"5","key":"10.1016\/j.jconrel.2026.115067_bb0150","doi-asserted-by":"crossref","first-page":"807","DOI":"10.1113\/expphysiol.2006.033506","article-title":"Oxygen sensing by mitochondria at complex III: the paradox of increased reactive oxygen species during hypoxia","volume":"91","author":"Guzy","year":"2006","journal-title":"Exp. Physiol."},{"issue":"10","key":"10.1016\/j.jconrel.2026.115067_bb0155","doi-asserted-by":"crossref","first-page":"1693","DOI":"10.1016\/j.yexcr.2006.02.007","article-title":"Hypoxia inhibits the growth, differentiation and bone-forming capacity of rat osteoblasts","volume":"312","author":"Utting","year":"2006","journal-title":"Exp. Cell Res."},{"issue":"15","key":"10.1016\/j.jconrel.2026.115067_bb0160","doi-asserted-by":"crossref","DOI":"10.1002\/advs.202207224","article-title":"Hypoxia drives material-induced heterotopic bone formation by enhancing osteoclastogenesis via M2\/lipid-loaded macrophage axis","volume":"10","author":"Li","year":"2023","journal-title":"Adv. Sci."},{"issue":"12","key":"10.1016\/j.jconrel.2026.115067_bb0165","doi-asserted-by":"crossref","DOI":"10.1073\/pnas.2418023122","article-title":"Dnmt3a-mediated hypermethylation of FoxO3 promotes redox imbalance during osteoclastogenesis","volume":"122","author":"Zhang","year":"2025","journal-title":"Proc. Natl. Acad. Sci."},{"issue":"10","key":"10.1016\/j.jconrel.2026.115067_bb0170","doi-asserted-by":"crossref","first-page":"1055","DOI":"10.1093\/abbs\/gmaa098","article-title":"ROS signaling cascades: dual regulations for osteoclast and osteoblast","volume":"52","author":"Tao","year":"2020","journal-title":"Acta Biochim. Biophys. Sin."},{"issue":"1","key":"10.1016\/j.jconrel.2026.115067_bb0175","doi-asserted-by":"crossref","first-page":"2","DOI":"10.1002\/jcp.10321","article-title":"Hypoxia is a major stimulator of osteoclast formation and bone resorption","volume":"196","author":"Arnett","year":"2003","journal-title":"J. Cell. Physiol."},{"issue":"2","key":"10.1016\/j.jconrel.2026.115067_bb0180","doi-asserted-by":"crossref","first-page":"256","DOI":"10.1002\/path.2534","article-title":"Acute hypoxia and osteoclast activity: a balance between enhanced resorption and increased apoptosis","volume":"218","author":"Knowles","year":"2009","journal-title":"J. Pathol."},{"issue":"5","key":"10.1016\/j.jconrel.2026.115067_bb0185","doi-asserted-by":"crossref","first-page":"374","DOI":"10.1002\/cbf.1660","article-title":"Hypoxia stimulates osteoclast formation from human peripheral blood","volume":"28","author":"Utting","year":"2010","journal-title":"Cell Biochem. Funct."},{"issue":"3","key":"10.1016\/j.jconrel.2026.115067_bb0190","doi-asserted-by":"crossref","first-page":"627","DOI":"10.1083\/jcb.11.3.627","article-title":"The fine structure of bone cells","volume":"11","author":"Dudley","year":"1961","journal-title":"J. Biophys. Biochem. Cytol."},{"key":"10.1016\/j.jconrel.2026.115067_bb0195","doi-asserted-by":"crossref","first-page":"252","DOI":"10.22203\/eCM.v033a19","article-title":"The effect of extracellular acidosis on the behaviour of mesenchymal stem cells in vitro","volume":"33","author":"Massa","year":"2017","journal-title":"Eur. Cells Mater."},{"issue":"1","key":"10.1016\/j.jconrel.2026.115067_bb0200","doi-asserted-by":"crossref","first-page":"119","DOI":"10.1210\/endo-119-1-119","article-title":"Effect of pH on bone resorption by rat osteoclasts in vitro","volume":"119","author":"Arnett","year":"1986","journal-title":"Endocrinology"},{"issue":"2","key":"10.1016\/j.jconrel.2026.115067_bb0205","doi-asserted-by":"crossref","first-page":"415S","DOI":"10.1093\/jn\/138.2.415S","article-title":"Extracellular pH regulates bone cell function","volume":"138","author":"Arnett","year":"2008","journal-title":"J. Nutr."},{"issue":"1","key":"10.1016\/j.jconrel.2026.115067_bb0210","doi-asserted-by":"crossref","first-page":"144","DOI":"10.1002\/jcp.21103","article-title":"The in vitro effect of pH on osteoclasts and bone resorption in the cat: implications for the pathogenesis of FORL","volume":"213","author":"Muzylak","year":"2007","journal-title":"J. Cell. Physiol."},{"issue":"3","key":"10.1016\/j.jconrel.2026.115067_bb0215","doi-asserted-by":"crossref","first-page":"167","DOI":"10.1007\/s00223-004-0285-8","article-title":"Acidosis inhibits bone formation by osteoblasts in vitro by preventing mineralization","volume":"77","author":"Brandao-Burch","year":"2005","journal-title":"Calcif. Tissue Int."},{"issue":"2","key":"10.1016\/j.jconrel.2026.115067_bb0220","doi-asserted-by":"crossref","first-page":"178","DOI":"10.1007\/s00223001107","article-title":"Acid pH increases carbonic anhydrase II and calcitonin receptor mRNA expression in mature osteoclasts","volume":"67","author":"Biskobing","year":"2000","journal-title":"Calcif. Tissue Int."},{"issue":"7","key":"10.1016\/j.jconrel.2026.115067_bb0225","doi-asserted-by":"crossref","DOI":"10.1126\/sciadv.aax0672","article-title":"Osteoblastic lysosome plays a central role in mineralization","volume":"5","author":"Iwayama","year":"2019","journal-title":"Sci. Adv."},{"issue":"2","key":"10.1016\/j.jconrel.2026.115067_bb0230","doi-asserted-by":"crossref","first-page":"1440","DOI":"10.1002\/jcp.30617","article-title":"Inhibition of hypoxia-induced mucin 1 alters the proteomic composition of human osteoblast-produced extracellular matrix, leading to reduced osteogenic and angiogenic potential","volume":"237","author":"Jadaun","year":"2022","journal-title":"J. Cell. Physiol."},{"key":"10.1016\/j.jconrel.2026.115067_bb0235","doi-asserted-by":"crossref","DOI":"10.7554\/eLife.69348","article-title":"Pseudohypoxic HIF pathway activation dysregulates collagen structure-function in human lung fibrosis","volume":"11","author":"Brereton","year":"2022","journal-title":"eLife"},{"issue":"31","key":"10.1016\/j.jconrel.2026.115067_bb0240","doi-asserted-by":"crossref","first-page":"7300","DOI":"10.1039\/D3TB00670K","article-title":"Oxygen-releasing biomaterials for regenerative medicine","volume":"11","author":"Wang","year":"2023","journal-title":"J. Mater. Chem. B"},{"key":"10.1016\/j.jconrel.2026.115067_bb0245","article-title":"Advances in oxygen-releasing matrices for regenerative engineering applications","author":"Zeng","year":"2025","journal-title":"Med. Biol. Eng. Comput."},{"issue":"20","key":"10.1016\/j.jconrel.2026.115067_bb0250","doi-asserted-by":"crossref","DOI":"10.1002\/adfm.202101040","article-title":"Oxygen self-sufficient nanoplatform for enhanced and selective antibacterial photodynamic therapy against anaerobe-induced periodontal disease","volume":"31","author":"Sun","year":"2021","journal-title":"Adv. Funct. Mater."},{"issue":"4","key":"10.1016\/j.jconrel.2026.115067_bb0255","doi-asserted-by":"crossref","first-page":"513","DOI":"10.1002\/jor.22805","article-title":"Hyperbaric oxygen therapy improves angiogenesis and bone formation in critical sized diaphyseal defects","volume":"33","author":"Grassmann","year":"2015","journal-title":"J. Orthop. Res."},{"issue":"1","key":"10.1016\/j.jconrel.2026.115067_bb0260","doi-asserted-by":"crossref","first-page":"98","DOI":"10.1111\/wrr.12253","article-title":"Hyperbaric oxygen therapy activates hypoxia-inducible factor 1 (HIF-1), which contributes to improved wound healing in diabetic mice","volume":"23","author":"Sunkari","year":"2015","journal-title":"Wound Repair Regen."},{"issue":"1","key":"10.1016\/j.jconrel.2026.115067_bb0265","doi-asserted-by":"crossref","first-page":"e29","DOI":"10.1016\/j.jss.2009.10.039","article-title":"Topical dissolved oxygen penetrates skin: model and method","volume":"159","author":"Roe","year":"2010","journal-title":"J. Surg. Res."},{"issue":"1","key":"10.1016\/j.jconrel.2026.115067_bb0270","doi-asserted-by":"crossref","first-page":"56","DOI":"10.1021\/acs.biomac.9b00546","article-title":"Advances in controlled oxygen generating biomaterials for tissue engineering and regenerative therapy","volume":"21","author":"Ashammakhi","year":"2020","journal-title":"Biomacromolecules"},{"issue":"31","key":"10.1016\/j.jconrel.2026.115067_bb0275","doi-asserted-by":"crossref","first-page":"4628","DOI":"10.1016\/j.biomaterials.2007.07.003","article-title":"Oxygen producing biomaterials for tissue regeneration","volume":"28","author":"Harrison","year":"2007","journal-title":"Biomaterials"},{"issue":"28","key":"10.1016\/j.jconrel.2026.115067_bb0280","doi-asserted-by":"crossref","first-page":"5698","DOI":"10.1039\/D1TB00178G","article-title":"3D printed polycaprolactone\/beta-tricalcium phosphate\/magnesium peroxide oxygen releasing scaffold enhances oasteogenesis and implanted BMSCs survival in repairing the large bone defect","volume":"9","author":"Peng","year":"2021","journal-title":"J. Mater. Chem. B"},{"issue":"8","key":"10.1016\/j.jconrel.2026.115067_bb0285","doi-asserted-by":"crossref","first-page":"9626","DOI":"10.1021\/acsami.3c10807","article-title":"3D-printed magnesium peroxide-incorporated scaffolds with sustained oxygen release and enhanced photothermal performance for osteosarcoma multimodal treatments","volume":"16","author":"Haixia","year":"2024","journal-title":"ACS Appl. Mater. Interfaces"},{"issue":"15","key":"10.1016\/j.jconrel.2026.115067_bb0290","doi-asserted-by":"crossref","first-page":"8769","DOI":"10.1021\/es4020629","article-title":"Zinc dioxide nanoparticulates: a hydrogen peroxide source at moderate pH","volume":"47","author":"Wolanov","year":"2013","journal-title":"Environ. Sci. Technol."},{"issue":"3","key":"10.1016\/j.jconrel.2026.115067_bb0295","doi-asserted-by":"crossref","first-page":"131","DOI":"10.1007\/s13770-013-0391-7","article-title":"Controlled release of oxygen from PLGA-alginate layered matrix and its in vitro characterization on the viability of muscle cells under hypoxic environment","volume":"10","author":"Abdi","year":"2013","journal-title":"Tissue Eng. Regener. Med."},{"issue":"1","key":"10.1016\/j.jconrel.2026.115067_bb0300","doi-asserted-by":"crossref","first-page":"1371","DOI":"10.1038\/s41598-018-19906-w","article-title":"An injectable oxygen release system to augment cell survival and promote cardiac repair following myocardial infarction","volume":"8","author":"Fan","year":"2018","journal-title":"Sci. Rep."},{"issue":"35","key":"10.1016\/j.jconrel.2026.115067_bb0305","doi-asserted-by":"crossref","DOI":"10.1126\/sciadv.abj0153","article-title":"Sustained oxygenation accelerates diabetic wound healing by promoting epithelialization and angiogenesis and decreasing inflammation","volume":"7","author":"Guan","year":"2021","journal-title":"Sci. Adv."},{"key":"10.1016\/j.jconrel.2026.115067_bb0310","doi-asserted-by":"crossref","first-page":"376","DOI":"10.1016\/j.jconrel.2021.01.034","article-title":"Oxygen-release microspheres capable of releasing oxygen in response to environmental oxygen level to improve stem cell survival and tissue regeneration in ischemic hindlimbs","volume":"331","author":"Guan","year":"2021","journal-title":"J. Control. Release"},{"issue":"7","key":"10.1016\/j.jconrel.2026.115067_bb0315","doi-asserted-by":"crossref","first-page":"207","DOI":"10.1007\/s10856-015-5542-z","article-title":"Control of oxygen release from peroxides using polymers","volume":"26","author":"Steg","year":"2015","journal-title":"J. Mater. Sci. Mater. Med."},{"issue":"5","key":"10.1016\/j.jconrel.2026.115067_bb0320","doi-asserted-by":"crossref","first-page":"1045","DOI":"10.1002\/jbm.a.36879","article-title":"Regenerative engineered vascularized bone mediated by calcium peroxide","volume":"108","author":"Daneshmandi","year":"2020","journal-title":"J. Biomed. Mater. Res. A"},{"issue":"15","key":"10.1016\/j.jconrel.2026.115067_bb0325","doi-asserted-by":"crossref","first-page":"18639","DOI":"10.1021\/acsami.2c22982","article-title":"Injectable antioxidant and oxygen-releasing lignin composites to promote wound healing","volume":"15","author":"Balaji","year":"2023","journal-title":"ACS Appl. Mater. Interfaces"},{"issue":"1","key":"10.1016\/j.jconrel.2026.115067_bb0330","doi-asserted-by":"crossref","first-page":"409","DOI":"10.1021\/acsbiomaterials.2c00853","article-title":"Oxygen-generating scaffolds for cardiac tissue engineering applications","volume":"9","author":"Suvarnapathaki","year":"2023","journal-title":"ACS Biomater. Sci. Eng."},{"issue":"6","key":"10.1016\/j.jconrel.2026.115067_bb0335","doi-asserted-by":"crossref","first-page":"830","DOI":"10.1111\/wrr.12324","article-title":"Peroxide-based oxygen generating topical wound dressing for enhancing healing of dermal wounds","volume":"23","author":"Chandra","year":"2015","journal-title":"Wound Repair Regen."},{"issue":"5","key":"10.1016\/j.jconrel.2026.115067_bb0340","doi-asserted-by":"crossref","first-page":"2985","DOI":"10.1021\/acsbiomaterials.9b01789","article-title":"Oxygen-releasing scaffolds for accelerated bone regeneration","volume":"6","author":"Touri","year":"2020","journal-title":"ACS Biomater. Sci. Eng."},{"issue":"8","key":"10.1016\/j.jconrel.2026.115067_bb0345","doi-asserted-by":"crossref","first-page":"3005","DOI":"10.1039\/D0BM02071K","article-title":"CaO2\/gelatin oxygen slow-releasing microspheres facilitate tissue engineering efficiency for the osteonecrosis of femoral head by enhancing the angiogenesis and survival of grafted bone marrow mesenchymal stem cells","volume":"9","author":"Wang","year":"2021","journal-title":"Biomater. Sci."},{"issue":"26","key":"10.1016\/j.jconrel.2026.115067_bb0350","doi-asserted-by":"crossref","first-page":"29506","DOI":"10.1021\/acsami.2c04378","article-title":"3D printed integrated bionic oxygenated scaffold for bone regeneration","volume":"14","author":"Wang","year":"2022","journal-title":"ACS Appl. Mater. Interfaces"},{"issue":"16","key":"10.1016\/j.jconrel.2026.115067_bb0355","doi-asserted-by":"crossref","first-page":"5560","DOI":"10.1039\/D3BM00650F","article-title":"Scaffolds with high oxygen content support osteogenic cell survival under hypoxia","volume":"11","author":"Augustine","year":"2023","journal-title":"Biomater. Sci."},{"key":"10.1016\/j.jconrel.2026.115067_bb0360","doi-asserted-by":"crossref","DOI":"10.1016\/j.biomaterials.2023.122179","article-title":"Self-oxygenation of engineered living tissues orchestrates osteogenic commitment of mesenchymal stem cells","volume":"300","author":"Hassan","year":"2023","journal-title":"Biomaterials"},{"key":"10.1016\/j.jconrel.2026.115067_bb0365","first-page":"64","article-title":"Oxygen generating scaffolds regenerate critical size bone defects","volume":"13","author":"Suvarnapathaki","year":"2022","journal-title":"Bioact. Mater."},{"key":"10.1016\/j.jconrel.2026.115067_bb0370","doi-asserted-by":"crossref","DOI":"10.1016\/j.colsurfb.2021.112007","article-title":"A hydrogel\/particle composite with a gradient of oxygen releasing microparticle for concurrent osteogenic and chondrogenic differentiation in a single scaffold","volume":"207","author":"Khorshidi","year":"2021","journal-title":"Colloids Surf. B: Biointerfaces"},{"issue":"4","key":"10.1016\/j.jconrel.2026.115067_bb0375","doi-asserted-by":"crossref","first-page":"627","DOI":"10.3390\/ph16040627","article-title":"Fabrication and characterization of oxygen-generating polylactic acid\/calcium peroxide composite filaments for bone scaffolds","volume":"16","author":"Mohammed","year":"2023","journal-title":"Pharmaceuticals"},{"key":"10.1016\/j.jconrel.2026.115067_bb0380","doi-asserted-by":"crossref","first-page":"231","DOI":"10.1016\/j.actbio.2022.09.077","article-title":"Oxygen-releasing hydrogels promote burn healing under hypoxic conditions","volume":"154","author":"Bai","year":"2022","journal-title":"Acta Biomater."},{"issue":"10","key":"10.1016\/j.jconrel.2026.115067_bb0385","doi-asserted-by":"crossref","first-page":"2384","DOI":"10.1021\/acsbiomaterials.7b00297","article-title":"Oxygen-releasing coatings for improved tissue preservation","volume":"3","author":"Forget","year":"2017","journal-title":"ACS Biomater. Sci. Eng."},{"issue":"1","key":"10.1016\/j.jconrel.2026.115067_bb0390","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1038\/s41427-022-00456-7","article-title":"A photothermal-response oxygen release platform based on a hydrogel for accelerating wound healing","volume":"15","author":"Li","year":"2023","journal-title":"NPG Asia Mater."},{"issue":"22","key":"10.1016\/j.jconrel.2026.115067_bb0395","doi-asserted-by":"crossref","first-page":"18458","DOI":"10.1021\/acsami.8b01736","article-title":"Oxygen-releasing antioxidant cryogel scaffolds with sustained oxygen delivery for tissue engineering applications","volume":"10","author":"Shiekh","year":"2018","journal-title":"ACS Appl. Mater. Interfaces"},{"issue":"50","key":"10.1016\/j.jconrel.2026.115067_bb0400","doi-asserted-by":"crossref","first-page":"59720","DOI":"10.1021\/acsami.1c19681","article-title":"pH-responsive oxygen and hydrogen peroxide self-supplying nanosystem for photodynamic and chemodynamic therapy of wound infection","volume":"13","author":"Ma","year":"2021","journal-title":"ACS Appl. Mater. Interfaces"},{"issue":"27","key":"10.1016\/j.jconrel.2026.115067_bb0405","doi-asserted-by":"crossref","first-page":"8260","DOI":"10.1073\/pnas.1505405112","article-title":"Microneedle-array patches loaded with hypoxia-sensitive vesicles provide fast glucose-responsive insulin delivery","volume":"112","author":"Yu","year":"2015","journal-title":"Proc. Natl. Acad. Sci."},{"issue":"8","key":"10.1016\/j.jconrel.2026.115067_bb0410","doi-asserted-by":"crossref","first-page":"1366","DOI":"10.1111\/j.1349-7006.2009.01195.x","article-title":"Significance of nitroimidazole compounds and hypoxia-inducible factor-1 for imaging tumor hypoxia","volume":"100","author":"Kizaka-Kondoh","year":"2009","journal-title":"Cancer Sci."},{"key":"10.1016\/j.jconrel.2026.115067_bb0415","doi-asserted-by":"crossref","first-page":"4361","DOI":"10.1038\/s41467-024-48719-x","article-title":"Controlled oxygen delivery to power tissue regeneration","volume":"15","author":"Zoneff","year":"2024","journal-title":"Nat. Commun."},{"issue":"3","key":"10.1016\/j.jconrel.2026.115067_bb0420","doi-asserted-by":"crossref","first-page":"223","DOI":"10.1007\/BF00582188","article-title":"The oxygen binding capacity of human haemoglobin: H\u00fcfner\u2019s factor redetermined","volume":"369","author":"Dijkhuizen","year":"1977","journal-title":"Pflugers Arch. - Eur. J. Physiol."},{"key":"10.1016\/j.jconrel.2026.115067_bb0425","doi-asserted-by":"crossref","DOI":"10.1016\/j.ccr.2025.216508","article-title":"Hemoglobin based oxygen carrier and its application in biomedicine","volume":"532","author":"Liu","year":"2025","journal-title":"Coord. Chem. Rev."},{"issue":"19","key":"10.1016\/j.jconrel.2026.115067_bb0430","doi-asserted-by":"crossref","DOI":"10.3390\/ijms241914902","article-title":"How nitric oxide hindered the search for hemoglobin-based oxygen carriers as human blood substitutes","volume":"24","author":"Samaja","year":"2023","journal-title":"Int. J. Mol. Sci."},{"key":"10.1016\/j.jconrel.2026.115067_bb0435","doi-asserted-by":"crossref","DOI":"10.1016\/j.blre.2022.100927","article-title":"A new era in oxygen therapeutics? From perfluorocarbon systems to haemoglobin-based oxygen carriers","volume":"54","author":"Charbe","year":"2022","journal-title":"Blood Rev."},{"issue":"10","key":"10.1016\/j.jconrel.2026.115067_bb0440","doi-asserted-by":"crossref","first-page":"2260","DOI":"10.1038\/s12276-024-01323-x","article-title":"Taming hemoglobin chemistry\u2014a new hemoglobin-based oxygen carrier engineered with both decreased rates of nitric oxide scavenging and lipid oxidation","volume":"56","author":"Cooper","year":"2024","journal-title":"Exp. Mol. Med."},{"issue":"10","key":"10.1016\/j.jconrel.2026.115067_bb0445","doi-asserted-by":"crossref","first-page":"3292","DOI":"10.1021\/bm301085x","article-title":"Hemoglobin-based oxygen carrier microparticles: synthesis, properties, and in vitro and in vivo investigations","volume":"13","author":"Xiong","year":"2012","journal-title":"Biomacromolecules"},{"issue":"6","key":"10.1016\/j.jconrel.2026.115067_bb0450","doi-asserted-by":"crossref","first-page":"1816","DOI":"10.1021\/bm400204y","article-title":"Covalent core\u2013shell architecture of hemoglobin and human serum albumin as an artificial O2 carrier","volume":"14","author":"Tomita","year":"2013","journal-title":"Biomacromolecules"},{"issue":"13","key":"10.1016\/j.jconrel.2026.115067_bb0455","doi-asserted-by":"crossref","first-page":"13300","DOI":"10.1021\/acsnano.5c00691","article-title":"Biotin receptor-targeting PtIV oxygen carrying prodrug amphiphile for alleviating tumor hypoxia induced immune chemotherapy suppression","volume":"19","author":"Sun","year":"2025","journal-title":"ACS Nano"},{"issue":"3","key":"10.1016\/j.jconrel.2026.115067_bb0460","doi-asserted-by":"crossref","first-page":"127","DOI":"10.3109\/10731199.2011.581052","article-title":"Polyhemoglobin-superoxide dismutase-catalase-carbonic anhydrase: a novel biotechnology-based blood substitute that transports both oxygen and carbon dioxide and also acts as an antioxidant","volume":"39","author":"Bian","year":"2011","journal-title":"Artif. Cells Blood Substit. Immobil. Biotechnol."},{"issue":"3","key":"10.1016\/j.jconrel.2026.115067_bb0465","doi-asserted-by":"crossref","first-page":"157","DOI":"10.3109\/21691401.2015.1035479","article-title":"Extraction of superoxide dismutase, catalase, and carbonic anhydrase from stroma-free red blood cell hemolysate for the preparation of the nanobiotechnological complex of polyhemoglobin\u2013superoxide dismutase\u2013catalase\u2013carbonic","volume":"43","author":"Guo","year":"2015","journal-title":"Artif. Cells Nanomed. Biotechnol."},{"issue":"21","key":"10.1016\/j.jconrel.2026.115067_bb0470","doi-asserted-by":"crossref","DOI":"10.1002\/smll.201901254","article-title":"Responsive porous microcarriers with controllable oxygen delivery for wound healing","volume":"15","author":"Liu","year":"2019","journal-title":"Small"},{"key":"10.1016\/j.jconrel.2026.115067_bb0475","doi-asserted-by":"crossref","DOI":"10.1016\/j.biomaterials.2023.122029","article-title":"All-in-one bioactive properties of photothermal nanofibers for accelerating diabetic wound healing","volume":"295","author":"Zhao","year":"2023","journal-title":"Biomaterials"},{"issue":"9","key":"10.1016\/j.jconrel.2026.115067_bb0480","doi-asserted-by":"crossref","DOI":"10.1002\/anbr.202300019","article-title":"Silk fibroin particles as carriers in the development of hemoglobin-based oxygen carriers","volume":"3","author":"Pacheco","year":"2023","journal-title":"Adv. Nanobiomed. Res."},{"key":"10.1016\/j.jconrel.2026.115067_bb0485","doi-asserted-by":"crossref","DOI":"10.1016\/j.ijbiomac.2023.127275","article-title":"Structural and functional alterations of polydopamine-coated hemoglobin: new insights for the development of successful oxygen carriers","volume":"253","author":"Nadimifar","year":"2023","journal-title":"Int. J. Biol. Macromol."},{"issue":"10","key":"10.1016\/j.jconrel.2026.115067_bb0490","doi-asserted-by":"crossref","first-page":"3374","DOI":"10.1039\/D4TB01771D","article-title":"Hemoglobin-loaded ZIF-8 nanoparticles equipped with PEGylated metal-phenolic network coatings: an oxygen carrier with antioxidant and stealth properties","volume":"13","author":"Coll-Satue","year":"2025","journal-title":"J. Mater. Chem. B"},{"issue":"20","key":"10.1016\/j.jconrel.2026.115067_bb0495","doi-asserted-by":"crossref","first-page":"9200","DOI":"10.1021\/acs.chemmater.2c02190","article-title":"Metal-phenolic networks as broad-spectrum antioxidant coatings for hemoglobin nanoparticles working as oxygen carriers","volume":"34","author":"Chen","year":"2022","journal-title":"Chem. Mater."},{"key":"10.1016\/j.jconrel.2026.115067_bb0500","doi-asserted-by":"crossref","DOI":"10.1016\/j.bioadv.2023.213698","article-title":"Synthesis of bioactive hemoglobin-based oxygen carrier nanoparticles via metal-phenolic complexation","volume":"156","author":"Nadimifar","year":"2024","journal-title":"Biomater. Adv."},{"key":"10.1016\/j.jconrel.2026.115067_bb0505","doi-asserted-by":"crossref","DOI":"10.1016\/j.bioorg.2024.107464","article-title":"Efficient conversion of hemoglobin to a non-vasoactive oxygen carrier by site-specific cross-linking with azido acyl methyl phosphates followed by bio-orthogonal CuAAC with a bis-alkyne","volume":"149","author":"Kim","year":"2024","journal-title":"Bioorg. Chem."},{"issue":"12","key":"10.1016\/j.jconrel.2026.115067_bb0510","doi-asserted-by":"crossref","first-page":"11447","DOI":"10.1021\/acsomega.3c00275","article-title":"Hydroxyethyl starch\u2013bovine hemoglobin conjugate as an effective oxygen carrier with the ability to expand plasma","volume":"8","author":"Yan","year":"2023","journal-title":"ACS Omega"},{"issue":"1","key":"10.1016\/j.jconrel.2026.115067_bb0515","doi-asserted-by":"crossref","first-page":"1","DOI":"10.3109\/21691401.2014.964554","article-title":"A novel nanobiotherapeutic poly-[hemoglobin-superoxide dismutase-catalase-carbonic anhydrase] with no cardiac toxicity for the resuscitation of a rat model with 90 minutes of sustained severe hemorrhagic shock with loss of 2\/3 blood volume","volume":"43","author":"Bian","year":"2015","journal-title":"Artif. Cells Nanomed. Biotechnol."},{"issue":"40","key":"10.1016\/j.jconrel.2026.115067_bb0520","doi-asserted-by":"crossref","first-page":"5814","DOI":"10.1002\/adma.201302875","article-title":"Fabrication of red-blood-cell-like polyelectrolyte microcapsules and their deformation and recovery behavior through a microcapillary","volume":"25","author":"She","year":"2013","journal-title":"Adv. Mater."},{"issue":"2","key":"10.1016\/j.jconrel.2026.115067_bb0525","doi-asserted-by":"crossref","first-page":"139","DOI":"10.1007\/s00424-020-02482-2","article-title":"Perfluorocarbon-based oxygen carriers: from physics to physiology","volume":"473","author":"J\u00e4gers","year":"2021","journal-title":"Pflugers Arch. - Eur. J. Physiol."},{"issue":"6","key":"10.1016\/j.jconrel.2026.115067_bb0530","doi-asserted-by":"crossref","first-page":"567","DOI":"10.1080\/10731190600973824","article-title":"Perfluorocarbon-based oxygen delivery","volume":"34","author":"Riess","year":"2006","journal-title":"Artif. Cells Blood Substit. Biotechnol."},{"key":"10.1016\/j.jconrel.2026.115067_bb0535","doi-asserted-by":"crossref","DOI":"10.1038\/srep12778","article-title":"Safety evaluation of hemoglobin-albumin cluster \u201cHemoAct\u201d as a red blood cell substitute","volume":"5","author":"Haruki","year":"2015","journal-title":"Sci. Rep."},{"issue":"3","key":"10.1016\/j.jconrel.2026.115067_bb0540","article-title":"Bioinspired perfluorocarbon-based oxygen carriers with concave shape and deformable shell","volume":"7","author":"Fu","year":"2022","journal-title":"Adv. Mater. Technol."},{"issue":"11","key":"10.1016\/j.jconrel.2026.115067_bb0545","doi-asserted-by":"crossref","first-page":"2501","DOI":"10.3390\/cells9112501","article-title":"Functional, metabolic and morphologic results of ex vivo donor lung perfusion with a perfluorocarbon-based oxygen carrier nanoemulsion in a large animal transplantation model","volume":"9","author":"Inci","year":"2020","journal-title":"Cells"},{"key":"10.1016\/j.jconrel.2026.115067_bb0550","doi-asserted-by":"crossref","first-page":"173","DOI":"10.1016\/j.freeradbiomed.2024.02.002","article-title":"Novel perfluorocarbon-based oxygenation therapy alleviates post-SAH hypoxic brain injury by inhibiting HIF-1\u03b1","volume":"214","author":"Peng","year":"2024","journal-title":"Free Radic. Biol. Med."},{"issue":"1","key":"10.1016\/j.jconrel.2026.115067_bb0555","doi-asserted-by":"crossref","first-page":"10","DOI":"10.1016\/j.jatmed.2024.02.003","article-title":"Perfluorocarbon-based oxygen carriers: what is new in 2024?","volume":"3","author":"Zhao","year":"2024","journal-title":"J. Anesth. Transl. Med."},{"key":"10.1016\/j.jconrel.2026.115067_bb0560","doi-asserted-by":"crossref","first-page":"117","DOI":"10.1016\/j.coph.2020.08.010","article-title":"Alleviating tumor hypoxia with perfluorocarbon-based oxygen carriers","volume":"53","author":"Krafft","year":"2020","journal-title":"Curr. Opin. Pharmacol."},{"issue":"1","key":"10.1016\/j.jconrel.2026.115067_bb0565","doi-asserted-by":"crossref","DOI":"10.1002\/admt.202200643","article-title":"A predictive oxygen durability model to analyze oxygen consumption of insulin producing cells encapsulated within a highly oxygenated hydrogel","volume":"8","author":"Domingo-Lopez","year":"2023","journal-title":"Adv. Mater. Technol."},{"key":"10.1016\/j.jconrel.2026.115067_bb0570","doi-asserted-by":"crossref","DOI":"10.1016\/j.cis.2021.102407","article-title":"Therapeutic oxygen delivery by perfluorocarbon-based colloids","volume":"294","author":"Krafft","year":"2021","journal-title":"Adv. Colloid Interf. Sci."},{"issue":"4","key":"10.1016\/j.jconrel.2026.115067_bb0575","doi-asserted-by":"crossref","first-page":"723","DOI":"10.1080\/21691401.2017.1284858","article-title":"Functionality of albumin-derived perfluorocarbon-based artificial oxygen carriers in the Langendorff-heart\u2020","volume":"45","author":"Wrobeln","year":"2017","journal-title":"Artif. Cells Nanomed. Biotechnol."},{"issue":"20","key":"10.1016\/j.jconrel.2026.115067_bb0580","doi-asserted-by":"crossref","first-page":"8957","DOI":"10.7150\/thno.45035","article-title":"Oxygen carrier in core-shell fibers synthesized by coaxial electrospinning enhances Schwann cell survival and nerve regeneration","volume":"10","author":"Ma","year":"2020","journal-title":"Theranostics"},{"issue":"4","key":"10.1016\/j.jconrel.2026.115067_bb0585","doi-asserted-by":"crossref","first-page":"1711","DOI":"10.1039\/D3NR04925F","article-title":"Dual-responsive magnetic nanodroplets for controlled oxygen release via ultrasound and magnetic stimulation","volume":"16","author":"Galati","year":"2024","journal-title":"Nanoscale"},{"issue":"1","key":"10.1016\/j.jconrel.2026.115067_bb0590","doi-asserted-by":"crossref","first-page":"2190","DOI":"10.1021\/acsami.4c16776","article-title":"Prevention of protein adsorption and macrophage phagocytosis of perfluorocarbon-based microsized core\u2013shell artificial oxygen carriers by facile PEG coatings","volume":"17","author":"Xiao","year":"2025","journal-title":"ACS Appl. Mater. Interfaces"},{"issue":"37","key":"10.1016\/j.jconrel.2026.115067_bb0595","doi-asserted-by":"crossref","DOI":"10.1002\/ange.202208305","article-title":"Capture, storage, and release of oxygen by metal\u2013organic frameworks (MOFs)","volume":"134","author":"Sutton","year":"2022","journal-title":"Angew. Chem."},{"issue":"17","key":"10.1016\/j.jconrel.2026.115067_bb0600","doi-asserted-by":"crossref","first-page":"5748","DOI":"10.1002\/ange.201902810","article-title":"Structural transformation in metal\u2013organic frameworks for reversible binding of oxygen","volume":"131","author":"Zeng","year":"2019","journal-title":"Angew. Chem."},{"key":"10.1016\/j.jconrel.2026.115067_bb0605","doi-asserted-by":"crossref","DOI":"10.1016\/j.mehy.2024.111489","article-title":"Oxygen gas-filled metal-organic frameworks (MOFs) delivery system: a hypothetical design for injectable oxygen","volume":"192","author":"Singh","year":"2024","journal-title":"Med. Hypotheses"},{"issue":"6","key":"10.1016\/j.jconrel.2026.115067_bb0610","doi-asserted-by":"crossref","first-page":"697","DOI":"10.3390\/biom14060697","article-title":"Exploring therapeutic potential of catalase: strategies in disease prevention and management","volume":"14","author":"Anwar","year":"2024","journal-title":"Biomolecules"},{"issue":"10","key":"10.1016\/j.jconrel.2026.115067_bb0615","doi-asserted-by":"crossref","first-page":"1375","DOI":"10.1016\/j.jinorgbio.2009.07.011","article-title":"Catalytic scavenging of peroxynitrite by catalase","volume":"103","author":"Gebicka","year":"2009","journal-title":"J. Inorg. Biochem."},{"issue":"7","key":"10.1016\/j.jconrel.2026.115067_bb0620","doi-asserted-by":"crossref","first-page":"709","DOI":"10.1016\/S0891-5849(00)00512-8","article-title":"Modulation of catalase peroxidatic and catalatic activity by nitric oxide","volume":"30","author":"Brunelli","year":"2001","journal-title":"Free Radic. Biol. Med."},{"issue":"33","key":"10.1016\/j.jconrel.2026.115067_bb0625","doi-asserted-by":"crossref","first-page":"7143","DOI":"10.1002\/adma.201602111","article-title":"Catalase-loaded TaOx nanoshells as bio-nanoreactors combining high-Z element and enzyme delivery for enhancing radiotherapy","volume":"28","author":"Song","year":"2016","journal-title":"Adv. Mater."},{"key":"10.1016\/j.jconrel.2026.115067_bb0630","doi-asserted-by":"crossref","first-page":"1677","DOI":"10.2147\/IJN.S225807","article-title":"Multifunctional immunoliposomes combining catalase and PD-L1 antibodies overcome tumor hypoxia and enhance immunotherapeutic effects against melanoma","volume":"15","author":"Hei","year":"2020","journal-title":"Int. J. Nanomedicine"},{"key":"10.1016\/j.jconrel.2026.115067_bb0635","doi-asserted-by":"crossref","first-page":"13","DOI":"10.1016\/j.biomaterials.2017.05.025","article-title":"Catalase-loaded cisplatin-prodrug-constructed liposomes to overcome tumor hypoxia for enhanced chemo-radiotherapy of cancer","volume":"138","author":"Zhang","year":"2017","journal-title":"Biomaterials"},{"issue":"4","key":"10.1016\/j.jconrel.2026.115067_bb0640","doi-asserted-by":"crossref","first-page":"4742","DOI":"10.1021\/acsnano.9b01087","article-title":"Catalase-integrated hyaluronic acid as nanocarriers for enhanced photodynamic therapy in solid tumor","volume":"13","author":"Phua","year":"2019","journal-title":"ACS Nano"},{"issue":"40","key":"10.1016\/j.jconrel.2026.115067_bb0645","doi-asserted-by":"crossref","DOI":"10.1002\/adfm.201901932","article-title":"Fluorinated polyethylenimine to enable transmucosal delivery of photosensitizer-conjugated catalase for photodynamic therapy of orthotopic bladder tumors postintravesical instillation","volume":"29","author":"Li","year":"2019","journal-title":"Adv. Funct. Mater."},{"issue":"2","key":"10.1016\/j.jconrel.2026.115067_bb0650","doi-asserted-by":"crossref","first-page":"1586","DOI":"10.1021\/acsnano.9b06689","article-title":"Fluorinated chitosan to enhance transmucosal delivery of sonosensitizer-conjugated catalase for sonodynamic bladder cancer treatment post-intravesical instillation","volume":"14","author":"Li","year":"2020","journal-title":"ACS Nano"},{"issue":"3","key":"10.1016\/j.jconrel.2026.115067_bb0655","doi-asserted-by":"crossref","first-page":"939","DOI":"10.1002\/bab.2165","article-title":"Glucose oxidase: applications, sources, and recombinant production","volume":"69","author":"Khatami","year":"2022","journal-title":"Biotechnol. Appl. Biochem."},{"key":"10.1016\/j.jconrel.2026.115067_bb0660","doi-asserted-by":"crossref","first-page":"274","DOI":"10.1016\/j.actbio.2022.01.056","article-title":"Oxygen self-supplied enzyme nanogels for tumor targeting with amplified synergistic starvation and photodynamic therapy","volume":"142","author":"Fan","year":"2022","journal-title":"Acta Biomater."},{"issue":"9","key":"10.1016\/j.jconrel.2026.115067_bb0665","doi-asserted-by":"crossref","first-page":"2924","DOI":"10.1016\/j.apsb.2021.04.006","article-title":"Self-propelled nanomotor reconstructs tumor microenvironment through synergistic hypoxia alleviation and glycolysis inhibition for promoted anti-metastasis","volume":"11","author":"Yu","year":"2021","journal-title":"Acta Pharm. Sin. B"},{"key":"10.1016\/j.jconrel.2026.115067_bb0670","doi-asserted-by":"crossref","DOI":"10.1016\/j.biomaterials.2020.120106","article-title":"Biodegradable poly(\u03b3-glutamic acid)@glucose oxidase@carbon dot nanoparticles for simultaneous multimodal imaging and synergetic cancer therapy","volume":"252","author":"Zhang","year":"2020","journal-title":"Biomaterials"},{"issue":"8","key":"10.1016\/j.jconrel.2026.115067_bb0675","doi-asserted-by":"crossref","first-page":"9278","DOI":"10.1021\/acsanm.4c00795","article-title":"Glucose oxidase and catalase-loaded ZnS nanozymes for regulating the local microenvironment and promoting wound healing in diabetes","volume":"7","author":"Zhang","year":"2024","journal-title":"ACS Appl. Nano Mater."},{"key":"10.1016\/j.jconrel.2026.115067_bb0680","article-title":"Glucose-responsive and analgesic gel for diabetic subcutaneous abscess treatment by simultaneously boosting photodynamic therapy and relieving hypoxia","author":"Huang","year":"2025","journal-title":"Adv. Sci."},{"issue":"43","key":"10.1016\/j.jconrel.2026.115067_bb0685","doi-asserted-by":"crossref","DOI":"10.1073\/pnas.2207955119","article-title":"A genetically encoded system for oxygen generation in living cells","volume":"119","author":"Markhard","year":"2022","journal-title":"Proc. Natl. Acad. Sci. USA"},{"issue":"14","key":"10.1016\/j.jconrel.2026.115067_bb0690","doi-asserted-by":"crossref","first-page":"6060","DOI":"10.1039\/c3cs35486e","article-title":"Nanomaterials with enzyme-like characteristics (nanozymes): next-generation artificial enzymes","volume":"42","author":"Wei","year":"2013","journal-title":"Chem. Soc. Rev."},{"issue":"37","key":"10.1016\/j.jconrel.2026.115067_bb0695","doi-asserted-by":"crossref","DOI":"10.1002\/smll.202203400","article-title":"Catalase-like nanozymes: classification, catalytic mechanisms, and their applications","volume":"18","author":"Xu","year":"2022","journal-title":"Small"},{"issue":"1","key":"10.1016\/j.jconrel.2026.115067_bb0700","doi-asserted-by":"crossref","first-page":"485","DOI":"10.1021\/acsnano.1c07504","article-title":"A cascade nanozyme with amplified sonodynamic therapeutic effects through comodulation of hypoxia and immunosuppression against cancer","volume":"16","author":"Tao","year":"2022","journal-title":"ACS Nano"},{"issue":"27","key":"10.1016\/j.jconrel.2026.115067_bb0705","doi-asserted-by":"crossref","first-page":"11242","DOI":"10.1039\/D4DT00999A","article-title":"A Pt nanoenzyme- and BODIPY-loaded nanoscale covalent organic framework for relieving intratumoural hypoxia to enhance photodynamic therapy","volume":"53","author":"Zhang","year":"2024","journal-title":"Dalton Trans."},{"issue":"45","key":"10.1016\/j.jconrel.2026.115067_bb0710","doi-asserted-by":"crossref","first-page":"61805","DOI":"10.1021\/acsami.4c18066","article-title":"Nanozymes as glucose scavengers and oxygenerators for enhancing tumor radiotherapy","volume":"16","author":"Zhang","year":"2024","journal-title":"ACS Appl. Mater. Interfaces"},{"issue":"23","key":"10.1016\/j.jconrel.2026.115067_bb0715","doi-asserted-by":"crossref","first-page":"5185","DOI":"10.1039\/D3TB00372H","article-title":"A dual-nanozyme-loaded black phosphorus multifunctional therapeutic platform for combined photothermal\/photodynamic\/starvation cancer therapy","volume":"11","author":"Du","year":"2023","journal-title":"J. Mater. Chem. B"},{"key":"10.1016\/j.jconrel.2026.115067_bb0720","doi-asserted-by":"crossref","first-page":"402","DOI":"10.1016\/j.actbio.2024.05.010","article-title":"Outer membrane vesicle-wrapped manganese nanoreactor for augmenting cancer metalloimmunotherapy through hypoxia attenuation and immune stimulation","volume":"181","author":"Luo","year":"2024","journal-title":"Acta Biomater."},{"key":"10.1016\/j.jconrel.2026.115067_bb0725","doi-asserted-by":"crossref","DOI":"10.1039\/D5TB00533G","article-title":"A TME-responsive oxygen-self-supplying hybridized polymersome for synergistic triple-modal therapy and precision theranostics in hypoxic tumors","author":"Tang","year":"2025","journal-title":"J. Mater. Chem. B"},{"key":"10.1016\/j.jconrel.2026.115067_bb0730","doi-asserted-by":"crossref","DOI":"10.1016\/j.ejpb.2025.114776","article-title":"Enhanced chemotherapy in thyroid carcinoma: a MnO2-silica nanoreactor activated by H2O2\/GSH for hypoxia relief","volume":"214","author":"Wang","year":"2025","journal-title":"Eur. J. Pharm. Biopharm."},{"issue":"8","key":"10.1016\/j.jconrel.2026.115067_bb0735","doi-asserted-by":"crossref","first-page":"10341","DOI":"10.1021\/acsami.2c19198","article-title":"Multifunctional nanoplatform for mild microwave-enhanced thermal, antioxidative, and chemotherapeutic treatment of rheumatoid arthritis","volume":"15","author":"Zhang","year":"2023","journal-title":"ACS Appl. Mater. Interfaces"},{"issue":"8","key":"10.1016\/j.jconrel.2026.115067_bb0740","doi-asserted-by":"crossref","DOI":"10.1002\/advs.202413833","article-title":"A dual-targeting biomimetic nanoplatform integrates SDT\/CDT\/gas therapy to boost synergistic ferroptosis for orthotopic hepatocellular carcinoma therapy","volume":"12","author":"Meng","year":"2025","journal-title":"Adv. Sci."},{"issue":"6","key":"10.1016\/j.jconrel.2026.115067_bb0745","doi-asserted-by":"crossref","first-page":"493","DOI":"10.1016\/j.jbiosc.2023.03.001","article-title":"Microfluidic encapsulation of photosynthetic cyanobacteria in hydrogel microparticles augments oxygen delivery to rescue ischemic myocardium","volume":"135","author":"Stapleton","year":"2023","journal-title":"J. Biosci. Bioeng."},{"key":"10.1016\/j.jconrel.2026.115067_bb0750","doi-asserted-by":"crossref","DOI":"10.1016\/j.ijbiomac.2024.136669","article-title":"Microenvironmental pH modulating oxygen self-boosting microalgal prodrug carboxymethyl chitosan\/hyaluronic acid\/puerarin hydrogel for accelerating wound healing in diabetic rats","volume":"282","author":"Su","year":"2024","journal-title":"Int. J. Biol. Macromol."},{"issue":"21","key":"10.1016\/j.jconrel.2026.115067_bb0755","doi-asserted-by":"crossref","DOI":"10.1126\/sciadv.aba5996","article-title":"Engineered algae: a novel oxygen-generating system for effective treatment of hypoxic cancer","volume":"6","author":"Qiao","year":"2020","journal-title":"Sci. Adv."},{"issue":"1","key":"10.1016\/j.jconrel.2026.115067_bb0760","doi-asserted-by":"crossref","first-page":"1042","DOI":"10.1038\/s41467-024-45101-9","article-title":"Programmed microalgae-gel promotes chronic wound healing in diabetes","volume":"15","author":"Kang","year":"2024","journal-title":"Nat. Commun."},{"key":"10.1016\/j.jconrel.2026.115067_bb0765","doi-asserted-by":"crossref","first-page":"57","DOI":"10.1016\/j.mattod.2022.06.024","article-title":"Surface-engineered chlorella alleviated hypoxic tumor microenvironment for enhanced chemotherapy and immunotherapy of first-line drugs","volume":"58","author":"Gao","year":"2022","journal-title":"Mater. Today"},{"issue":"6","key":"10.1016\/j.jconrel.2026.115067_bb0770","doi-asserted-by":"crossref","first-page":"7725","DOI":"10.1021\/acsami.2c18809","article-title":"Separable microneedles with photosynthesis-driven oxygen manufactory for diabetic wound healing","volume":"15","author":"Zhao","year":"2023","journal-title":"ACS Appl. Mater. Interfaces"},{"issue":"15","key":"10.1016\/j.jconrel.2026.115067_bb0775","doi-asserted-by":"crossref","DOI":"10.1002\/adma.202307585","article-title":"Chlorella-loaded antibacterial microneedles for microacupuncture oxygen therapy of diabetic bacterial infected wounds","volume":"36","author":"Gao","year":"2024","journal-title":"Adv. Mater."},{"issue":"20","key":"10.1016\/j.jconrel.2026.115067_bb0780","doi-asserted-by":"crossref","DOI":"10.1126\/sciadv.aba4311","article-title":"Dissolved oxygen from microalgae-gel patch promotes chronic wound healing in diabetes","volume":"6","author":"Chen","year":"2020","journal-title":"Sci. Adv."},{"key":"10.1016\/j.jconrel.2026.115067_bb0785","article-title":"In situ 3D bioprinting living photosynthetic scaffolds for autotrophic wound healing","volume":"2022","author":"Wang","year":"2022","journal-title":"Research"},{"issue":"2","key":"10.1016\/j.jconrel.2026.115067_bb0790","doi-asserted-by":"crossref","first-page":"496","DOI":"10.1039\/D4BM00880D","article-title":"Utilizing photosynthetic oxygen-releasing biomaterials to modulate blood vessel growth in the chick embryo chorioallantoic membrane","volume":"13","author":"Wang","year":"2025","journal-title":"Biomater. Sci."},{"issue":"5","key":"10.1016\/j.jconrel.2026.115067_bb0795","doi-asserted-by":"crossref","DOI":"10.1016\/j.celbio.2025.100047","article-title":"Photosynthesis pneumatic patch promoted deep-wound healing","volume":"1","author":"Li","year":"2025","journal-title":"Cell Biomater."},{"issue":"1","key":"10.1016\/j.jconrel.2026.115067_bb0800","doi-asserted-by":"crossref","first-page":"4495","DOI":"10.1038\/s41467-022-32066-w","article-title":"Engineering micro oxygen factories to slow tumour progression via hyperoxic microenvironments","volume":"13","author":"Wang","year":"2022","journal-title":"Nat. Commun."},{"key":"10.1016\/j.jconrel.2026.115067_bb0805","article-title":"Plant-cell machinery for making metabolites transferred to mammalian cells","year":"2022","journal-title":"Nature"},{"issue":"7","key":"10.1016\/j.jconrel.2026.115067_bb0810","doi-asserted-by":"crossref","first-page":"869","DOI":"10.1038\/s41477-020-0694-3","article-title":"Structural variability, coordination and adaptation of a native photosynthetic machinery","volume":"6","author":"Zhao","year":"2020","journal-title":"Nat. Plants"},{"key":"10.1016\/j.jconrel.2026.115067_bb0815","first-page":"1","article-title":"Bioengineered photosynthetic nanothylakoids reshape the inflammatory microenvironment for rheumatoid arthritis therapy","author":"Li","year":"2025","journal-title":"Nat. Nanotechnol."},{"issue":"4","key":"10.1016\/j.jconrel.2026.115067_bb0820","doi-asserted-by":"crossref","first-page":"387","DOI":"10.1038\/nnano.2016.269","article-title":"Complement proteins bind to nanoparticle protein corona and undergo dynamic exchange in vivo","volume":"12","author":"Chen","year":"2017","journal-title":"Nat. Nanotechnol."},{"key":"10.1016\/j.jconrel.2026.115067_bb0825","doi-asserted-by":"crossref","first-page":"115","DOI":"10.1016\/j.jconrel.2023.02.022","article-title":"Perspectives on complement and phagocytic cell responses to nanoparticles: from fundamentals to adverse reactions","volume":"356","author":"Moghimi","year":"2023","journal-title":"J. Control. Release"},{"key":"10.1016\/j.jconrel.2026.115067_bb0830","doi-asserted-by":"crossref","first-page":"227","DOI":"10.1016\/j.ejpb.2023.11.006","article-title":"Activation of the complement system by nanoparticles and strategies for complement inhibition","volume":"193","author":"Haroon","year":"2023","journal-title":"Eur. J. Pharm. Biopharm."},{"key":"10.1016\/j.jconrel.2026.115067_bb0835","doi-asserted-by":"crossref","DOI":"10.3389\/fimmu.2020.603039","article-title":"Nanoparticle-induced complement activation: implications for cancer nanomedicine","volume":"11","author":"La-Beck","year":"2021","journal-title":"Front. Immunol."},{"issue":"1","key":"10.1016\/j.jconrel.2026.115067_bb0840","doi-asserted-by":"crossref","first-page":"36","DOI":"10.1016\/j.imlet.2009.10.007","article-title":"Regulation of human mast cell and basophil function by anaphylatoxins C3a and C5a","volume":"128","author":"Ali","year":"2010","journal-title":"Immunol. Lett."},{"key":"10.1016\/j.jconrel.2026.115067_bb0845","doi-asserted-by":"crossref","DOI":"10.3389\/fchem.2021.810029","article-title":"Perfluorocarbon emulsion contrast agents: a mini review","volume":"9","author":"Holman","year":"2022","journal-title":"Front. Chem."},{"key":"10.1016\/j.jconrel.2026.115067_bb0850","doi-asserted-by":"crossref","DOI":"10.1016\/j.envres.2023.117743","article-title":"Estimation of per- and polyfluoroalkyl substances (PFAS) half-lives in human studies: a systematic review and meta-analysis","volume":"242","author":"Rosato","year":"2024","journal-title":"Environ. Res."},{"key":"10.1016\/j.jconrel.2026.115067_bb0855","doi-asserted-by":"crossref","DOI":"10.1016\/j.envint.2023.107734","article-title":"Systematic review and meta-analysis of epidemiologic data on vaccine response in relation to exposure to five principal perfluoroalkyl substances","volume":"172","author":"Crawford","year":"2023","journal-title":"Environ. Int."},{"issue":"1","key":"10.1016\/j.jconrel.2026.115067_bb0860","doi-asserted-by":"crossref","first-page":"535","DOI":"10.1186\/s12951-022-01742-w","article-title":"Influence of magnetic nanoparticle biotransformation on contrasting efficiency and Iron metabolism","volume":"20","author":"Yaremenko","year":"2022","journal-title":"J. Nanobiotechnol."},{"issue":"30","key":"10.1016\/j.jconrel.2026.115067_bb0865","doi-asserted-by":"crossref","first-page":"5925","DOI":"10.1039\/D1TB01044A","article-title":"Biocompatibility and biodegradability of metal organic frameworks for biomedical applications","volume":"9","author":"Singh","year":"2021","journal-title":"J. Mater. Chem. B"},{"issue":"9","key":"10.1016\/j.jconrel.2026.115067_bb0870","doi-asserted-by":"crossref","first-page":"4980","DOI":"10.7150\/thno.128435","article-title":"Recent advances of metal-organic frameworks (MOFs) for drug delivery, cancer imaging and theranostics","volume":"16","author":"Yu","year":"2026","journal-title":"Theranostics"},{"key":"10.1016\/j.jconrel.2026.115067_bb0875","doi-asserted-by":"crossref","DOI":"10.1016\/j.cej.2023.144400","article-title":"Mitigating metal-organic framework (MOF) toxicity for biomedical applications","volume":"471","author":"Wi\u015bniewska","year":"2023","journal-title":"Chem. Eng. J."},{"issue":"37","key":"10.1016\/j.jconrel.2026.115067_bb0880","article-title":"Nanoparticles of metal-organic frameworks: on the road to in vivo efficacy in biomedicine","volume":"30","author":"Simon-Yarza","year":"2018","journal-title":"Adv. Mater."},{"key":"10.1016\/j.jconrel.2026.115067_bb0885","doi-asserted-by":"crossref","DOI":"10.1126\/sciadv.adj6380","article-title":"Zeolitic imidazolate frameworks activate endosomal toll-like receptors and potentiate immunogenicity of SARS-CoV-2 spike protein trimer","volume":"10","author":"Alsaiari","year":"2024","journal-title":"Sci. Adv."},{"issue":"44","key":"10.1016\/j.jconrel.2026.115067_bb0890","doi-asserted-by":"crossref","first-page":"50721","DOI":"10.1021\/acsami.2c20715","article-title":"Oxygen-generating biomaterials for translational bone regenerative engineering","volume":"15","author":"Hosseini","year":"2023","journal-title":"ACS Appl. Mater. Interfaces"},{"issue":"Pt 2","key":"10.1016\/j.jconrel.2026.115067_bb0895","article-title":"Oxygen-generating scaffolds: one step closer to the clinical translation of tissue engineered products","volume":"455","author":"Augustine","year":"2023","journal-title":"Chem. Eng. J. (Lausanne Switz.: 1996)"},{"issue":"20","key":"10.1016\/j.jconrel.2026.115067_bb0900","doi-asserted-by":"crossref","first-page":"3422","DOI":"10.1039\/C5TB02635K","article-title":"Oxygen delivering biomaterials for tissue engineering","volume":"4","author":"Farris","year":"2016","journal-title":"J. Mater. Chem. B Mater. Biol. Med."},{"issue":"1","key":"10.1016\/j.jconrel.2026.115067_bb0905","doi-asserted-by":"crossref","first-page":"65","DOI":"10.1038\/s41427-019-0166-2","article-title":"Breathing life into engineered tissues using oxygen-releasing biomaterials","volume":"11","author":"Suvarnapathaki","year":"2019","journal-title":"NPG Asia Mater."},{"issue":"1","key":"10.1016\/j.jconrel.2026.115067_bb0910","doi-asserted-by":"crossref","first-page":"91","DOI":"10.1039\/C7RA08758F","article-title":"Controlled chemical synthesis of CaO2 particles coated with polyethylene glycol: characterization of crystallite size and oxygen release kinetics","volume":"8","author":"Rastinfard","year":"2017","journal-title":"RSC Adv."},{"key":"10.1016\/j.jconrel.2026.115067_bb0915","article-title":"Gelatin-CaO2\/SAP\/PLGA composite scaffold enhances the reparation of critical-sized cranial defects by promoting seed cell survival","volume":"22","author":"Zhang","year":"2021","journal-title":"Appl. Mater. Today"},{"issue":"14","key":"10.1016\/j.jconrel.2026.115067_bb0920","doi-asserted-by":"crossref","first-page":"5378","DOI":"10.1021\/acs.chemmater.3c00601","article-title":"Hydroxyapatite nanocoating on calcium peroxide microparticles for sustained oxygen release","volume":"35","author":"Tomioka","year":"2023","journal-title":"Chem. Mater."},{"issue":"12","key":"10.1016\/j.jconrel.2026.115067_bb0925","doi-asserted-by":"crossref","first-page":"1439","DOI":"10.1002\/jbm.820281209","article-title":"Mineralization and pH relationships in healing skeletal defects grafted with demineralized bone matrix","volume":"28","author":"Chakkalakal","year":"1994","journal-title":"J. Biomed. Mater. Res."},{"issue":"9","key":"10.1016\/j.jconrel.2026.115067_bb0930","doi-asserted-by":"crossref","first-page":"9557","DOI":"10.1021\/acsami.8b20580","article-title":"Spatial distribution of biomaterial microenvironment pH and its modulatory effect on osteoclasts at the early stage of bone defect regeneration","volume":"11","author":"Liu","year":"2019","journal-title":"ACS Appl. Mater. Interfaces"},{"issue":"3","key":"10.1016\/j.jconrel.2026.115067_bb0935","first-page":"205","article-title":"Hydrogel microspheres for bone regeneration through regulation of the regenerative microenvironment","volume":"5","author":"Zhang","year":"2024","journal-title":"BMT"},{"issue":"17","key":"10.1016\/j.jconrel.2026.115067_bb0940","doi-asserted-by":"crossref","first-page":"3864","DOI":"10.3390\/ma13173864","article-title":"Facile fabrication of oxygen-releasing tannylated calcium peroxide nanoparticles","volume":"13","author":"Park","year":"2020","journal-title":"Materials"},{"key":"10.1016\/j.jconrel.2026.115067_bb0945","doi-asserted-by":"crossref","DOI":"10.3389\/fbioe.2021.749057","article-title":"Effect of pH on the electrochemical behavior of hydrogen peroxide in the presence of Pseudomonas Aeruginosa","volume":"9","author":"Espinoza-Vergara","year":"2021","journal-title":"Front. Bioeng. Biotechnol."},{"key":"10.1016\/j.jconrel.2026.115067_bb0950","article-title":"Three-dimensional covalent organic frameworks as enzyme nanoprotector: preserving the activity of catalase in acidic environment for hypoxia cancer therapy","volume":"19","author":"Wan","year":"2022","journal-title":"Mater. Today Nano"},{"key":"10.1016\/j.jconrel.2026.115067_bb0955","doi-asserted-by":"crossref","DOI":"10.1093\/rb\/rbaf070","article-title":"Hypoxic niches established via endogenous oxygen production in scaffold under anoxia for enhanced bone regeneration","volume":"12","author":"Gan","year":"2025","journal-title":"Regener. Biomater."},{"key":"10.1016\/j.jconrel.2026.115067_bb0960","doi-asserted-by":"crossref","DOI":"10.3389\/fbioe.2024.1292171","article-title":"Oxygen generating biomaterials at the forefront of regenerative medicine: advances in bone regeneration","volume":"12","author":"Zhao","year":"2024","journal-title":"Front. Bioeng. Biotechnol."},{"issue":"4","key":"10.1016\/j.jconrel.2026.115067_bb0965","doi-asserted-by":"crossref","first-page":"1393","DOI":"10.3390\/ma16041393","article-title":"Novel artificial scaffold for bone marrow regeneration: honeycomb tricalcium phosphate","volume":"16","author":"Inada","year":"2023","journal-title":"Materials"},{"issue":"44","key":"10.1016\/j.jconrel.2026.115067_bb0970","doi-asserted-by":"crossref","first-page":"12380","DOI":"10.1073\/pnas.1608438113","article-title":"Oxygen delivery using engineered microparticles","volume":"113","author":"Seekell","year":"2016","journal-title":"Proc. Natl. Acad. Sci."},{"issue":"1","key":"10.1016\/j.jconrel.2026.115067_bb0975","doi-asserted-by":"crossref","first-page":"25","DOI":"10.1186\/s12951-024-03060-9","article-title":"Therapeutic delivery of oxygen using artificial oxygen carriers demonstrates the possibility of treating a wide range of diseases","volume":"23","author":"Mohanto","year":"2025","journal-title":"J. Nanobiotechnol."},{"key":"10.1016\/j.jconrel.2026.115067_bb0980","doi-asserted-by":"crossref","first-page":"450","DOI":"10.1016\/j.cej.2016.05.123","article-title":"Properties of calcium peroxide for release of hydrogen peroxide and oxygen: a kinetics study","volume":"303","author":"Wang","year":"2016","journal-title":"Chem. Eng. J."},{"key":"10.1016\/j.jconrel.2026.115067_bb0985","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1042\/bse0590001","article-title":"Enzymes: principles and biotechnological applications","volume":"59","author":"Robinson","year":"2015","journal-title":"Essays Biochem."},{"issue":"6","key":"10.1016\/j.jconrel.2026.115067_bb0990","doi-asserted-by":"crossref","first-page":"843","DOI":"10.1002\/pi.4502","article-title":"Oxygen releasing biomaterials for tissue engineering","volume":"62","author":"Camci-Unal","year":"2013","journal-title":"Polym. Int."},{"issue":"7","key":"10.1016\/j.jconrel.2026.115067_bb0995","doi-asserted-by":"crossref","first-page":"854","DOI":"10.3390\/bioengineering10070854","article-title":"Hydrogel-impregnated self-oxygenating electrospun scaffolds for bone tissue engineering","volume":"10","author":"Augustine","year":"2023","journal-title":"Bioengineering"},{"issue":"22","key":"10.1016\/j.jconrel.2026.115067_bb1000","doi-asserted-by":"crossref","first-page":"5577","DOI":"10.3390\/ma17225577","article-title":"Biocomposite scaffolds for tissue engineering: materials, fabrication techniques and future directions","volume":"17","author":"Sultana","year":"2024","journal-title":"Materials"},{"issue":"7","key":"10.1016\/j.jconrel.2026.115067_bb1005","doi-asserted-by":"crossref","first-page":"602","DOI":"10.3390\/pharmaceutics12070602","article-title":"The overview of porous, bioactive scaffolds as instructive biomaterials for tissue regeneration and their clinical translation","volume":"12","author":"Lutzweiler","year":"2020","journal-title":"Pharmaceutics"},{"key":"10.1016\/j.jconrel.2026.115067_bb1010","doi-asserted-by":"crossref","first-page":"511","DOI":"10.3389\/fbioe.2020.00511","article-title":"Optimizing an injectable composite oxygen-generating system for relieving tissue hypoxia","volume":"8","author":"Hsieh","year":"2020","journal-title":"Front. Bioeng. Biotechnol."},{"issue":"4","key":"10.1016\/j.jconrel.2026.115067_bb1015","doi-asserted-by":"crossref","first-page":"74","DOI":"10.3390\/computation12040074","article-title":"Computational modelling and simulation of scaffolds for bone tissue engineering","volume":"12","author":"Musthafa","year":"2024","journal-title":"Computation"},{"issue":"7","key":"10.1016\/j.jconrel.2026.115067_bb1020","doi-asserted-by":"crossref","first-page":"2519","DOI":"10.1039\/D0BM02048F","article-title":"Engineering calcium peroxide based oxygen generating scaffolds for tissue survival","volume":"9","author":"Suvarnapathaki","year":"2021","journal-title":"Biomater. Sci."},{"key":"10.1016\/j.jconrel.2026.115067_bb1025","doi-asserted-by":"crossref","DOI":"10.1016\/j.biomaterials.2022.121943","article-title":"Oxygen-supplying syringe to create hyperoxia-inducible hydrogels for in situ tissue regeneration","volume":"293","author":"Kang","year":"2023","journal-title":"Biomaterials"},{"issue":"5","key":"10.1016\/j.jconrel.2026.115067_bb1030","doi-asserted-by":"crossref","first-page":"5903","DOI":"10.1021\/acsomega.3c09406","article-title":"Controlled release of oxygen from calcium peroxide in a weak acidic condition by stabilized amorphous calcium carbonate nanocoating for biomedical applications","volume":"9","author":"Tomioka","year":"2024","journal-title":"ACS Omega"},{"issue":"12","key":"10.1016\/j.jconrel.2026.115067_bb1035","doi-asserted-by":"crossref","first-page":"1174","DOI":"10.7150\/thno.4410","article-title":"Theranostic oxygen delivery using ultrasound and microbubbles","volume":"2","author":"Kwan","year":"2012","journal-title":"Theranostics"},{"key":"10.1016\/j.jconrel.2026.115067_bb1040","article-title":"Injectable, oxygen-releasing, thermosensitive hydrogel promotes vascularized bone formation with prolonged oxygen delivery and improved osteoinductivity","volume":"29","author":"Xu","year":"2024","journal-title":"Mater. Today Bio"},{"issue":"2","key":"10.1016\/j.jconrel.2026.115067_bb1045","doi-asserted-by":"crossref","DOI":"10.1016\/j.heliyon.2020.e03451","article-title":"A comparison of models for the analysis of the kinetics of drug release from PLGA-based nanoparticles","volume":"6","author":"Pourtalebi Jahromi","year":"2020","journal-title":"Heliyon"},{"issue":"21","key":"10.1016\/j.jconrel.2026.115067_bb1050","doi-asserted-by":"crossref","DOI":"10.1002\/adfm.202010609","article-title":"Scaffold fabrication technologies and structure\/function properties in bone tissue engineering","volume":"31","author":"Collins","year":"2021","journal-title":"Adv. Funct. Mater."},{"issue":"1","key":"10.1016\/j.jconrel.2026.115067_bb1055","article-title":"Addressing the challenges of infectious bone defects: a review of recent advances in bifunctional biomaterials","volume":"23","author":"Zhang","year":"2025","journal-title":"J. Nanobiotechnol."},{"issue":"12","key":"10.1016\/j.jconrel.2026.115067_bb1060","doi-asserted-by":"crossref","first-page":"774","DOI":"10.1038\/nri.2017.103","article-title":"Regulation of immunity and inflammation by hypoxia in immunological niches","volume":"17","author":"Taylor","year":"2017","journal-title":"Nat. Rev. Immunol."},{"issue":"48","key":"10.1016\/j.jconrel.2026.115067_bb1065","doi-asserted-by":"crossref","first-page":"47585","DOI":"10.1021\/acsomega.4c06642","article-title":"Flowable oxygen-release hydrogel inhibits bacteria and treats periodontitis","volume":"9","author":"Wang","year":"2024","journal-title":"ACS Omega"},{"issue":"7","key":"10.1016\/j.jconrel.2026.115067_bb1070","doi-asserted-by":"crossref","first-page":"385","DOI":"10.1038\/nrrheum.2016.69","article-title":"Hypoxia, mitochondrial dysfunction and synovial invasiveness in rheumatoid arthritis","volume":"12","author":"Fearon","year":"2016","journal-title":"Nat. Rev. Rheumatol."},{"issue":"1","key":"10.1016\/j.jconrel.2026.115067_bb1075","doi-asserted-by":"crossref","first-page":"6758","DOI":"10.1038\/s41467-022-34481-5","article-title":"Nanozyme-reinforced hydrogel as a H2O2-driven oxygenerator for enhancing prosthetic interface osseointegration in rheumatoid arthritis therapy","volume":"13","author":"Zhao","year":"2022","journal-title":"Nat. Commun."},{"key":"10.1016\/j.jconrel.2026.115067_bb1080","first-page":"100","article-title":"Guidelines for clinical diagnosis and treatment of osteonecrosis of the femoral head in adults (2019 version)","volume":"21","author":"Zhao","year":"2020","journal-title":"J. Orthop. Transl."},{"issue":"1","key":"10.1016\/j.jconrel.2026.115067_bb1085","doi-asserted-by":"crossref","first-page":"5062","DOI":"10.1038\/s41598-017-05488-6","article-title":"eIF2\u03b1 signaling regulates ischemic osteonecrosis through endoplasmic reticulum stress","volume":"7","author":"Liu","year":"2017","journal-title":"Sci. Rep."},{"issue":"7","key":"10.1016\/j.jconrel.2026.115067_bb1090","first-page":"445","article-title":"Chinese expert consensus on the management of fracture risk in diabetic patients","volume":"11","author":"Chinese Society of Osteoporosis and Bone Mineral Research; Chinese Medical Association; Chinese Society of Endocrinology; Chinese Medical Association; Chinese Diabetes Society; Chinese Medical Association; Chinese Endocrinologist Association; Chinese Medical Doctor Association","year":"2019","journal-title":"Chin. J. Diabetes"},{"issue":"20","key":"10.1016\/j.jconrel.2026.115067_bb1095","doi-asserted-by":"crossref","DOI":"10.1002\/adfm.202101372","article-title":"3D printed enzyme-functionalized scaffold facilitates diabetic bone regeneration","volume":"31","author":"Yang","year":"2021","journal-title":"Adv. Funct. Mater."},{"issue":"2","key":"10.1016\/j.jconrel.2026.115067_bb1100","doi-asserted-by":"crossref","first-page":"2677","DOI":"10.1021\/acsnano.4c14596","article-title":"Multifaceted catalytic glucose depletion and reactive oxygen species-scavenging nanoenzyme composite hydrogel for facilitating diabetic bone regeneration","volume":"19","author":"Liu","year":"2025","journal-title":"ACS Nano"},{"issue":"4","key":"10.1016\/j.jconrel.2026.115067_bb1105","doi-asserted-by":"crossref","first-page":"e1974","DOI":"10.1002\/term.2628","article-title":"A review on gradient hydrogel\/fiber scaffolds for osteochondral regeneration","volume":"12","author":"Khorshidi","year":"2018","journal-title":"J. Tissue Eng. Regen. Med."},{"issue":"1","key":"10.1016\/j.jconrel.2026.115067_bb1110","doi-asserted-by":"crossref","first-page":"305","DOI":"10.1016\/j.bbrc.2011.11.105","article-title":"Oxygen tension regulates the osteogenic, chondrogenic and endochondral phenotype of bone marrow derived mesenchymal stem cells","volume":"417","author":"Sheehy","year":"2012","journal-title":"Biochem. Biophys. Res. Commun."},{"key":"10.1016\/j.jconrel.2026.115067_bb1115","article-title":"Microsphere strategy to generate conformal bone organoid units with osteoimmunomodulation and sustainable oxygen supply for bone regeneration","author":"Deng","year":"2025","journal-title":"Adv. Sci."},{"key":"10.1016\/j.jconrel.2026.115067_bb1120","first-page":"29","article-title":"Bone\/cartilage organoid on-chip: construction strategy and application","volume":"25","author":"Hu","year":"2023","journal-title":"Bioact. Mater."},{"issue":"2","key":"10.1016\/j.jconrel.2026.115067_bb1125","doi-asserted-by":"crossref","first-page":"682","DOI":"10.7150\/thno.105840","article-title":"Standardization and consensus in the development and application of bone organoids","volume":"15","author":"Wang","year":"2025","journal-title":"Theranostics"},{"key":"10.1016\/j.jconrel.2026.115067_bb1130","doi-asserted-by":"crossref","DOI":"10.1016\/j.biomaterials.2022.121990","article-title":"Electrical stimulation of piezoelectric BaTiO3 coated Ti6Al4V scaffolds promotes anti-inflammatory polarization of macrophages and bone repair via MAPK\/JNK inhibition and OXPHOS activation","volume":"293","author":"Wu","year":"2023","journal-title":"Biomaterials"},{"key":"10.1016\/j.jconrel.2026.115067_bb1135","first-page":"227","article-title":"Fabricating oxygen self-supplying 3D printed bioactive hydrogel scaffold for augmented vascularized bone regeneration","volume":"40","author":"Yang","year":"2024","journal-title":"Bioact. Mater."},{"issue":"31","key":"10.1016\/j.jconrel.2026.115067_bb1140","doi-asserted-by":"crossref","first-page":"40682","DOI":"10.1021\/acsami.4c08350","article-title":"In situ hydrogel with immobilized Mn-porphyrin for reactive oxygen species scavenging, oxygen generation, and risedronate delivery in bone defect treatment","volume":"16","author":"Kim","year":"2024","journal-title":"ACS Appl. Mater. Interfaces"},{"key":"10.1016\/j.jconrel.2026.115067_bb1145","doi-asserted-by":"crossref","DOI":"10.1016\/j.nantod.2021.101297","article-title":"Photosynthetic oxygen-self-generated 3D-printing microbial scaffold enhances osteosarcoma elimination and prompts bone regeneration","volume":"41","author":"He","year":"2021","journal-title":"Nano Today"},{"key":"10.1016\/j.jconrel.2026.115067_bb1150","doi-asserted-by":"crossref","DOI":"10.1016\/j.bioadv.2024.213893","article-title":"Oxygen tension regulating hydrogels for vascularization and osteogenesis via sequential activation of HIF-1\u03b1 and ERK1\/2 signaling pathways in bone regeneration","volume":"161","author":"Yin","year":"2024","journal-title":"Biomater. Adv."},{"key":"10.1016\/j.jconrel.2026.115067_bb1155","doi-asserted-by":"crossref","DOI":"10.1016\/j.ijbiomac.2024.132970","article-title":"Exosome-loaded hyaluronic acid hydrogel composite with oxygen-producing 3D printed polylactic acid scaffolds for bone tissue repair and regeneration","volume":"274","author":"Zhang","year":"2024","journal-title":"Int. J. Biol. Macromol."},{"issue":"13","key":"10.1016\/j.jconrel.2026.115067_bb1160","doi-asserted-by":"crossref","first-page":"5808","DOI":"10.1021\/acs.chemmater.2c00376","article-title":"Oxygen-enriched osteoinductive nanoerythrocytes augment cell survival and osteogenic differentiation for bone regeneration","volume":"34","author":"Lee","year":"2022","journal-title":"Chem. Mater."},{"issue":"2","key":"10.1016\/j.jconrel.2026.115067_bb1165","doi-asserted-by":"crossref","first-page":"1087","DOI":"10.1021\/acs.biomac.8b01760","article-title":"Oxygen-releasing microparticles for cell survival and differentiation ability under hypoxia for effective bone regeneration","volume":"20","author":"Kim","year":"2019","journal-title":"Biomacromolecules"},{"key":"10.1016\/j.jconrel.2026.115067_bb1170","doi-asserted-by":"crossref","DOI":"10.1016\/j.biomaterials.2025.123926","article-title":"Biomimetic and microenvironment-adaptive nanoplatform potentiates photodynamic therapy of rheumatoid arthritis via H2S-modulated oxygen metabolism","volume":"329","author":"Zhang","year":"2026","journal-title":"Biomaterials"},{"key":"10.1016\/j.jconrel.2026.115067_bb1175","doi-asserted-by":"crossref","first-page":"566","DOI":"10.1016\/j.actbio.2025.11.041","article-title":"Oxygen-self-supplying biomimetic nanozymes synergize with methotrexate to reprogram macrophage polarization for rheumatoid arthritis therapy","volume":"209","author":"Lv","year":"2026","journal-title":"Acta Biomater."},{"issue":"20","key":"10.1016\/j.jconrel.2026.115067_bb1180","doi-asserted-by":"crossref","DOI":"10.1002\/smll.202307379","article-title":"Neutrophil-mimetic, ROS responsive, and oxygen generating nanovesicles for targeted interventions of refractory rheumatoid arthritis","volume":"20","author":"Tang","year":"2024","journal-title":"Small"},{"key":"10.1016\/j.jconrel.2026.115067_bb1185","doi-asserted-by":"crossref","DOI":"10.1016\/j.ijbiomac.2025.142014","article-title":"Photodriven PtPdCo-TiO2 heterostructure modified with hyaluronic acid and folic acid enhances antioxidative stress through efficient hydrogen\/oxygen delivery and thermal effects in rheumatoid arthritis therapy","volume":"307","author":"Wu","year":"2025","journal-title":"Int. J. Biol. Macromol."},{"key":"10.1016\/j.jconrel.2026.115067_bb1190","doi-asserted-by":"crossref","DOI":"10.1016\/j.redox.2025.103574","article-title":"Dual-driven selenium Janus single-atom nanomotors for autonomous regulating mitochondrial oxygen imbalance to catalytic therapy of rheumatoid arthritis","volume":"81","author":"Chen","year":"2025","journal-title":"Redox Biol."},{"issue":"21","key":"10.1016\/j.jconrel.2026.115067_bb1195","doi-asserted-by":"crossref","DOI":"10.1002\/smll.202207319","article-title":"A metabolic driven bio-responsive hydrogel loading psoralen for therapy of rheumatoid arthritis","volume":"19","author":"Wang","year":"2023","journal-title":"Small"},{"issue":"41","key":"10.1016\/j.jconrel.2026.115067_bb1200","doi-asserted-by":"crossref","DOI":"10.1002\/advs.202506737","article-title":"A \u201cmesoporous oxygen chamber\u201d scaffold with antibacterial and early immunomodulatory effect for promoting bone regeneration","volume":"12","author":"Fu","year":"2025","journal-title":"Adv. Sci."},{"issue":"2","key":"10.1016\/j.jconrel.2026.115067_bb1205","doi-asserted-by":"crossref","first-page":"932","DOI":"10.1021\/acsbiomaterials.3c00493","article-title":"Small extracellular vesicles laden oxygen-releasing thermosensitive hydrogel for enhanced antibacterial therapy against anaerobe-induced periodontitis alveolar bone defect","volume":"10","author":"Ming","year":"2024","journal-title":"ACS Biomater. Sci. Eng."},{"issue":"7","key":"10.1016\/j.jconrel.2026.115067_bb1210","doi-asserted-by":"crossref","first-page":"11117","DOI":"10.1021\/acsami.5c25694","article-title":"A 3D-printed composite hydrogel engineered with a coordination-reprogrammed nanozyme for synergistic chemo-physical bone therapy","volume":"18","author":"Qiu","year":"2026","journal-title":"ACS Appl. Mater. Interfaces"},{"key":"10.1016\/j.jconrel.2026.115067_bb1215","doi-asserted-by":"crossref","DOI":"10.1038\/s41467-025-65165-5","article-title":"Microenvironment-responsive multifunctional enzyme-linked hydrogel for diabetic bone defect regeneration","volume":"16","author":"Fu","year":"2025","journal-title":"Nat. Commun."},{"issue":"29","key":"10.1016\/j.jconrel.2026.115067_bb1220","doi-asserted-by":"crossref","DOI":"10.1002\/adfm.202500320","article-title":"Bioadaptable 3D printed scaffold for microenvironment-activatable visualization and osteogenesis in diabetic bone defect","volume":"35","author":"Feng","year":"2025","journal-title":"Adv. Funct. Mater."},{"key":"10.1016\/j.jconrel.2026.115067_bb1225","doi-asserted-by":"crossref","DOI":"10.1016\/j.ijbiomac.2024.138945","article-title":"Methacrylated silk fibroin based composite hydrogel with ROS-scavenging and osteogenic ability to orchestrate diabetic bone regeneration","volume":"294","author":"Wang","year":"2025","journal-title":"Int. J. Biol. Macromol."},{"issue":"32","key":"10.1016\/j.jconrel.2026.115067_bb1230","doi-asserted-by":"crossref","DOI":"10.1002\/adhm.202402596","article-title":"Hydrogel microsphere-encapsulated bimetallic nanozyme for promoting diabetic bone regeneration via glucose consumption and ROS scavenging","volume":"13","author":"Hui","year":"2024","journal-title":"Adv. Healthc. Mater."},{"issue":"1","key":"10.1016\/j.jconrel.2026.115067_bb1235","doi-asserted-by":"crossref","first-page":"639","DOI":"10.1186\/s12951-024-02865-y","article-title":"From ROS scavenging to boosted osseointegration: cerium-containing mesoporous bioactive glass nanoparticles functionalized implants in diabetes","volume":"22","author":"Jiang","year":"2024","journal-title":"J. Nanobiotechnol."},{"issue":"5","key":"10.1016\/j.jconrel.2026.115067_bb1240","doi-asserted-by":"crossref","first-page":"363","DOI":"10.1615\/CritRevBiomedEng.v40.i5.10","article-title":"Bone tissue engineering: recent advances and challenges","volume":"40","author":"Amini","year":"2012","journal-title":"Crit. Rev. Biomed. Eng."},{"key":"10.1016\/j.jconrel.2026.115067_bb1245","author":"Ega\u00f1a"},{"key":"10.1016\/j.jconrel.2026.115067_bb1250","author":"Metwally"},{"key":"10.1016\/j.jconrel.2026.115067_bb1255","author":"Najafi"},{"key":"10.1016\/j.jconrel.2026.115067_bb1260","author":"Neogenix"},{"key":"10.1016\/j.jconrel.2026.115067_bb1265","author":"Lavery"},{"issue":"3","key":"10.1016\/j.jconrel.2026.115067_bb1270","doi-asserted-by":"crossref","first-page":"540","DOI":"10.1016\/j.tibtech.2024.09.006","article-title":"Engineering next-gen oxygen-generating scaffolds to enhance bone regeneration","volume":"43","author":"Zhao","year":"2025","journal-title":"Trends Biotechnol."},{"issue":"37","key":"10.1016\/j.jconrel.2026.115067_bb1275","doi-asserted-by":"crossref","first-page":"33548","DOI":"10.1021\/acsami.9b08341","article-title":"Electrospun fiber mesh for high-resolution measurements of oxygen tension in cranial bone defect repair","volume":"11","author":"Schilling","year":"2019","journal-title":"ACS Appl. Mater. Interfaces"}],"container-title":["Journal of Controlled Release"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0168365926004700?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0168365926004700?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,8,24]],"date-time":"2026-08-24T13:51:56Z","timestamp":1787579516000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0168365926004700"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,8]]},"references-count":255,"alternative-id":["S0168365926004700"],"URL":"https:\/\/doi.org\/10.1016\/j.jconrel.2026.115067","relation":{},"ISSN":["0168-3659"],"issn-type":[{"value":"0168-3659","type":"print"}],"subject":[],"published":{"date-parts":[[2026,8]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Oxygen-releasing biomaterials for bone tissue regeneration","name":"articletitle","label":"Article Title"},{"value":"Journal of Controlled Release","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.jconrel.2026.115067","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2026 Elsevier B.V. All rights are reserved, including those for text and data mining, AI training, and similar technologies.","name":"copyright","label":"Copyright"}],"article-number":"115067"}}