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Goldust, M. Golechha, P. Goleij, N.G.M. Gomes, P.N. Gona, S.V. Gopalani, G. Gorini, H. Goudarzi, A.C. Goulart, B.N.G. Goulart, A. Goyal, A. Grada, S.M. Graham, M. Grivna, G. Grosso, S.-Y. Guan, G. Guarducci, M.I.M. Gubari, M.D. Gudeta, A. Guha, S. Guicciardi, R.A. Guimar\u00e3es, S. Gulati, D.A. Gunawardane, S. Gunturu, C. Guo, A.K. Gupta, B. Gupta, M.K. Gupta, M. Gupta, R.D. Gupta, R. Gupta, S. Gupta, V.B. Gupta, Gupta, V.K., L. Gurmessa, R.A. Guti\u00e9rrez, F. Habibzadeh, P. Habibzadeh, R. Haddadi, M. Hadei, N.R. Hadi, N. Haep, N. Hafezi-Nejad, A. Hailu, A. Haj-Mirzaian, E.S. Halboub, B.J. Hall, S. Haller, R. Halwani, R.R. Hamadeh, S. Hameed, S. Hamidi, E.B. Hamilton, C. Han, Q. Han, A. Hanif, N. Hanifi, G.J. Hankey, F. Hanna, M.A. Hannan, M.N. Haque, H. Harapan, A. Hargono, J.M. Haro, A.I. Hasaballah, I. Hasan, M.T. Hasan, H. Hasani, M. Hasanian, A. Hashi, M.S. Hasnain, I. Hassan, S. Hassanipour, H. Hassankhani, J. Haubold, R.J. Havmoeller, S.I. Hay, J. He, J.J. Hebert, O.E. 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Jaiswal, E. Jamshidi, M.M. Janko, A.I. Jatau, S. Javadov, T. Javaheri, S.K. Jayapal, S. Jayaram, R. Jebai, S.H. Jee, J. Jeganathan, A.K. Jha, R.P. Jha, H. Jiang, Y. Jin, O. Johnson, M. Jokar, J.B. Jonas, T. Joo, A. Joseph, N. Joseph, C.E. Joshua, G. Joshy, J.J. Jozwiak, M. J\u00fcrisson, V. K, B. Kaambwa, A. Kabir, Z. Kabir, V. Kadashetti, D.H. Kadir, R. Kalani, L.R. Kalankesh, L.R. Kalankesh, F. Kaliyadan, S. Kalra, V.K. Kamal, S.K. Kamarajah, R. Kamath, Z. Kamiab, N. Kamyari, T. Kanagasabai, T. Kanchan, H. Kandel, A.R. Kanmanthareddy, E.W. Kanmiki, K.K. Kanmodi, S. Kannan, S.K. Kansal, R.S. Kantar, N. Kapoor, M. Karajizadeh, S.D. Karanth, R.A. Karasneh, I.M. Karaye, A. Karch, A. Karim, S.E. Karimi, A. Karimi Behnagh, F.Z. Kashoo, Q.H.A. Kasnazani, H. Kasraei, N.J. Kassebaum, M.B. Kassel, J.H. Kauppila, N. Kaur, N. Kawakami, G.A. Kayode, F. Kazemi, S. Kazemian, T.H. Kazmi, G.M. Kebebew, A.D. Kebede, F. Kebede, T.S. Keflie, P.N. Keiyoro, C. Keller, J.T. Kelly, J.H. Kempen, J.A. Kerr, E. Kesse-Guyot, H. Khajuria, A. Khalaji, N. Khalid, A.A. Khalil, A. Khalilian, F. Khamesipour, A. Khan, A. Khan, G. Khan, Khan, I.A., M.N. Khan, Khan, M.J. Khan, M.A.B. Khan, Z.A. M.Z. Khan Suheb, S. Khanmohammadi, K. Khatab, F. Khatami, H. Khatatbeh, M.M. Khatatbeh, A. Khavandegar, H.R. Khayat Kashani, F.F. Khidri, E. Khodadoust, M. Khorgamphar, M. Khormali, Z. Khorrami, A. Khosravi, M.A. Khosravi, Z.D. Kifle, G. Kim, J. Kim, K. Kim, M.S. Kim, Y.J. Kim, R.W. Kimokoti, K.E. Kinzel, A. Kisa, S. Kisa, D. Klu, A.K.S. Knudsen, J.M. Kocarnik, S. Kochhar, T. Kocsis, D.S.Q. Koh, A.-A. Kolahi, K. Kolves, F. Kompani, G. Koren, S. Kosen, K. Kostev, P.A. Koul, S.L. Koulmane Laxminarayana, K. Krishan, H. Krishna, V. Krishna, V. Krishnamoorthy, Y. Krishnamoorthy, K.J. Krohn, B. Kuate Defo, B. Kucuk Bicer, M.A. Kuddus, M. Kuddus, I. Kuitunen, M. Kulimbet, V. Kulkarni, A. Kumar, A. Kumar, H. Kumar, M. Kumar, R. Kumar, M. Kumari, F.T. Kumie, S. Kundu, O.P. Kurmi, A. Kusnali, D. Kusuma, A. Kwarteng, I. Kyriopoulos, H.H. Kyu, C. La Vecchia, B. Lacey, M.A. Ladan, L. Laflamme, A.K. Lagat, A.C.J. Lager, A. Lahmar, D.T.C. Lai, D.K. Lal, R. Lalloo, T. Lallukka, H. Lam, J. L\u00e1m, K.R. Landrum, F. Lanfranchi, J.J. Lang, B. Langguth, V.C. Lansingh, A. Laplante-L\u00e9vesque, B. Larijani, A.O. Larsson, S. Lasrado, Z.S. Lassi, K. Latief, K. Latifinaibin, P. Lauriola, N.H.H. Le, T.T.T. Le, T.D.T. Le, C. Ledda, J.R. Ledesma, M. Lee, P.H. Lee, Lee, S.W., H. Lee, W.-C. Lee, Y.H. Lee, K.E. LeGrand, J. Leigh, E. Leong, T.L. Lerango, M.-C. Li, W. Li, X. Li, Y. Li, Z. Li, V.S. Ligade, A.T.M. Likaka, L.-L. Lim, S.S. Lim, M. Lindstrom, C. Linehan, C. Liu, G. Liu, J. Liu, R. Liu, S. Liu, Liu, X., E. Llanaj, M.J. Loftus, R. L\u00f3pez-Bueno, P.D. Lopukhov, A.M. Loreche, S. Lorkowski, P.A. Lotufo, R. Lozano, J. Lubinda, G. Lucchetti, A. Lugo, R. Lunevicius, Z.F. Ma, K.L. Maass, N. Machairas, M. Machoy, F. Madadizadeh, C. Madsen, \u00c1.M. Madureira-Carvalho, A.A. Maghazachi, S.B. Maharaj, S. Mahjoub, M.A. Mahmoud, A. Mahmoudi, E. Mahmoudi, R. Mahmoudi, A. Majeed, I.F. Makhdoom, E. Malakan Rad, V. Maled, R. Malekzadeh, A.K. Malhotra, K. Malhotra, A.A. Malik, I. Malik, D.C. Malta, A.A. Mamun, P. Mansouri, M.A. Mansournia, L.G. Mantovani, S. Maqsood, B.P. Marasini, H.R. Marateb, J.C. Maravilla, A.M. Marconi, P. Mardi, M. Marino, A. Marjani, G. Martinez, B.A. Martinez-Guerra, R. Martinez-Piedra, D. Martini, S. Martini, F.R. Martins-Melo, M. Martorell, W. Marx, S. Maryam, R.R. Marzo, A. Masaka, A. Masrie, S. Mathieson, A.G. Mathioudakis, M.R. Mathur, J. Mattumpuram, R. Matzopoulos, R.J. Maude, A. Maugeri, P.K. Maulik, M. Mayeli, M. Mazaheri, M. Mazidi, J.J. McGrath, M. McKee, A.L.W. McKowen, S.A. McLaughlin, S.M. McPhail, E.A. Mechili, J.R.C. Medina, R.P. Mediratta, J.K. Meena, R. Mehra, K. Mehrabani-Zeinabad, E. Mehrabi Nasab, T. Mekene Meto, G.G. Meles, M.A.M. Mendez-Lopez, W. Mendoza, R.G. Menezes, B. Mengist, A.-F.A. Mentis, S.A. Meo, H.A. Meresa, A. Meretoja, T.J. Meretoja, A.M. Mersha, B.A. Mesfin, T. Mestrovic, K.C.D. Mettananda, S. Mettananda, P. Meylakhs, A. Mhlanga, L. Mhlanga, T. Mi, T. Miazgowski, G. Micha, I.M. Michalek, T.R. Miller, E.J. Mills, L.H.N. Minh, G.K. Mini, P. Mir Mohammad Sadeghi, A. Mirica, A. Mirijello, E.M. Mirrakhimov, M.K. Mirutse, M. Mirzaei, A. Misganaw, A. Mishra, S. Misra, P.B. Mitchell, P. Mithra, C. Mittal, M. Mobayen, M.E. Moberg, A. Mohamadkhani, J. Mohamed, M.F.H. Mohamed, N.S. Mohamed, S. Mohammad-Alizadeh-Charandabi, S. Mohammadi, A. Mohammadian-Hafshejani, N. Mohammadifard, H. Mohammed, H. Mohammed, M. Mohammed, Mohammed, S., V. Mohan, H. Mojiri-Forushani, A. Mokari, A.H. Mokdad, S. Molinaro, M. Molokhia, S. Momtazmanesh, L. Monasta, S. Mondello, M.A. Moni, A. Moodi Ghalibaf, M. Moradi, Y. Moradi, M. Moradi-Lakeh, M. Moradzadeh, P. Moraga, L. Morawska, R.S. Moreira, N. Morovatdar, S.D. Morrison, J. Morze, J.F. Mosser, R. Motappa, V. Mougin, S. Mouodi, P. Mousavi, S.E. Mousavi, A. Mousavi Khaneghah, E.A. Mpolya, M. Mrejen, S. Mubarik, L. Muccioli, U.O. Mueller, F. Mughal, S. Mukherjee, F. Mulita, K. Munjal, E. Murillo-Zamora, F. Musaigwa, K.M. Musallam, A. Mustafa, G. Mustafa, S. Muthupandian, R. Muthusamy, M. Muzaffar, W. Myung, A.J. Nagarajan, G. Nagel, P. Naghavi, A. Naheed, G.R. Naik, G. Naik, F. Nainu, S. Nair, H.H.R. Najmuldeen, N. Nakhostin Ansari, V. Nangia, A.A. Naqvi, S. Narasimha Swamy, A.I. Narayana, S. Nargus, B.R. Nascimento, G.G. Nascimento, S. Nasehi, A.J. Nashwan, Z.S. Natto, J. Nauman, M. Naveed, B.P. Nayak, V.C. Nayak, A. Nazri-Panjaki, R. Ndejjo, S.O. Nduaguba, H. Negash, I. Negoi, R.I. Negoi, S.M. Negru, S.A. Nejadghaderi, C. Nejjari, E. Nena, S. Nepal, M. Ng, H.A. Nggada, G. Nguefack-Tsague, J.W. Ngunjiri, A.H. Nguyen, D.H. Nguyen, H.T.H. Nguyen, P.T. Nguyen, V.T. Nguyen, R.K. Niazi, K.R. Nielsen, Y.T. Nigatu, T.K. Nikolouzakis, A. Nikoobar, F. Nikoomanesh, A.R. Nikpoor, D.N.A. Ningrum, C.A. Nnaji, L.A. Nnyanzi, E.A. Noman, S. Nomura, M. Noreen, N. Noroozi, B. Norrving, J.J. Noubiap, A. Novotney, C.A. Nri-Ezedi, G. Ntaios, M. Ntsekhe, V. Nu\u00f1ez-Samudio, D. Nurrika, J.J. Nutor, B. Oancea, K.O. Obamiro, M.A. Oboh, I.A. Odetokun, N.M. Odogwu, M.J. O'Donnell, M.S. Oduro, A.O.D. Ofakunrin, A. Ogunkoya, A.S. Oguntade, I.-H. Oh, H. Okati-Aliabad, S.R. Okeke, A.P. Okekunle, O.C. Okonji, A.T. Olagunju, M.T. Olaiya, M.I. Olatubi, G.M.M. Oliveira, I.I. Olufadewa, B.O. Olusanya, J.O. Olusanya, Y.D. Oluwafemi, H.A. Omar, A. Omar Bali, G.L. Omer, M.A. Ondayo, S. Ong, O.E. Onwujekwe, K.I. Onyedibe, M. Ordak, O.E. Orisakwe, V.N. Orish, D.V. Ortega-Altamirano, A. Ortiz, W.M.S. Osman, S.M. Ostroff, U.L. Osuagwu, A. Otoiu, N. Otstavnov, S.S. Otstavnov, A. Ouyahia, G. Ouyang, M.O. Owolabi, Y. Ozten, M.P. P A, A. Padron-Monedero, J.R. Padubidri, P.K. Pal, T. Palicz, C. Palladino, R. Palladino, R.F. Palma-Alvarez, F. Pan, H.-F. Pan, A. Pana, P. Panda, S. Panda-Jonas, S.R. Pandi-Perumal, H.U. Pangaribuan, G.D. Panos, L.D. Panos, I. Pantazopoulos, A.M. Pantea Stoian, P. Papadopoulou, R.R. Parikh, S. Park, A. Parthasarathi, A. Pashaei, M. Pasovic, R. Passera, D.K. Pasupula, H.M. Patel, J. Patel, S.K. Patel, S. Patil, D. Patoulias, V.S. Patthipati, U. Paudel, H. Pazoki Toroudi, S.A. Pease, A.E. Peden, P. Pedersini, U. Pensato, V.C.F. Pepito, E.K. Peprah, P. Peprah, J. Perdig\u00e3o, M. Pereira, M.F.P. Peres, A. Perianayagam, N. Perico, R.G. Pestell, K. Pesudovs, F.E. Petermann-Rocha, W.A. Petri, H.T. Pham, A.K. Philip, M.R. Phillips, D. Pierannunzio, M. Pigeolet, D.M. Pigott, T. Pilgrim, Z.Z. Piracha, M.A. Piradov, S. Pirouzpanah, N. Plakkal, E. Plotnikov, V. Podder, D. Poddighe, S. Polinder, K.R. Polkinghorne, R. Poluru, V.T. Ponkilainen, F. Porru, M.J. Postma, G.R. Poudel, A. Pourshams, N. Pourtaheri, S.I. Prada, P.M.S. Pradhan, T.N. Prakasham, M. Prasad, A. Prashant, E.J.S. Prates, D. Prieto Alhambra, T. Priscilla, N. Pritchett, B.M. Purohit, J. Puvvula, N.H. Qasim, I. Qattea, A.S. Qazi, G. Qian, S. Qiu, M.F. Qureshi, M. Rabiee Rad, A. Radfar, R.A. Radhakrishnan, V. Radhakrishnan, H. Raeisi Shahraki, Q. Rafferty, A. Raggi, P.R. Raghav, N. Raheem, F. Rahim, M.J. Rahim, V. Rahimi-Movaghar, M.M. Rahman, M.H.U. Rahman, M. Rahman, M.A. Rahman, A.M. Rahmani, S. Rahmani, V. Rahmanian, S. Rajaa, P. Rajput, I. Rakovac, S.K. Ramasamy, S. Ramazanu, K. Rana, C.L. Ranabhat, N. Rancic, A. Rane, C.R. Rao, I.R. Rao, M. Rao, S.J. Rao, D.P. Rasali, D. Rasella, S. Rashedi, V. Rashedi, M.-M. Rashidi, A. Rasouli-Saravani, A. Rasul, G. Rathnaiah Babu, S.K. Rauniyar, R. Ravangard, N. Ravikumar, D.L. Rawaf, S. Rawaf, L. Rawal, R. Rawassizadeh, B. Rawlley, R.Z. Raza, C. Razo, E.M.M. Redwan, F.U. Rehman, L. Reifels, R.C. Reiner Jr, G. Remuzzi, L.F. Reyes, M. Rezaei, N. Rezaei, N. Rezaei, M. Rezaeian, T.G. Rhee, M.A. Riaz, A.L.P. Ribeiro, J. Rickard, H.R. Riva, H.E. Robinson-Oden, C.F. Rodrigues, M. Rodrigues, L. Roever, E.L.B. Rogowski, P. Rohloff, D.S. Romadlon, E. Romero-Rodr\u00edguez, M. Romoli, L. Ronfani, G. Roshandel, G.A. Roth, H.S. Rout, N. Roy, P. Roy, E. Rubagotti, G.D.A. Ruela, S.F. Rumisha, T. Runghien, G.M. Rwegerera, A. Rynkiewicz, C. S N, A.M.A. Saad, Z. Saadatian, K. Saber, M.M. Saber-Ayad, M. SaberiKamarposhti, S. Sabour, S. Sacco, P.S. Sachdev, R. Sachdeva, B. Saddik, A. Saddler, B.A. Sadee, E. Sadeghi, E. Sadeghi, F. Sadeghian, M.R. Saeb, U. Saeed, F. Safaeinejad, S.Z. Safi, R. Sagar, A. Saghazadeh, D. Sagoe, F. Saheb Sharif-Askari, N. Saheb Sharif-Askari, A. Sahebkar, S.S. Sahoo, U. Sahoo, M. Sahu, Z. Saif, M.R. Sajid, J.W. Sakshaug, N. Salam, P. Salamati, A.A. Salami, L.B. Salaroli, M.A. Saleh, S. Salehi, M.R. Salem, M.Z.Y. Salem, S. Salimi, H. Samadi Kafil, S. Samadzadeh, S. Samargandy, Y.L. Samodra, A.M. Samy, J. Sanabria, F. Sanna, D.F. Santomauro, I.S. Santos, M.M. Santric-Milicevic, B.P. Sao Jose, M.A. Sarasmita, S.Y.I. Saraswathy, A. Saravanan, B. Saravi, Y. Sarikhani, T. Sarkar, R. Sarmiento-Su\u00e1rez, G.S. Sarode, S.C. Sarode, A. Sarveazad, B. Sathian, T. Sathish, M. Satpathy, A. Sayeed, M.A. Sayeed, M. Saylan, M. Sayyah, N. Scarmeas, B.M. Schaarschmidt, M.P. Schlaich, W. Schlee, M.I. Schmidt, I.J.C. Schneider, A. Schuermans, A.E. Schumacher, A.E. Schutte, M. Schwarzinger, D.C. Schwebel, F. Schwendicke, M. \u0160ekerija, S. Selvaraj, S. Senapati, S. Senthilkumaran, S.G. Sepanlou, D. Serban, Y. Sethi, F. Sha, M. Shabany, A. Shafaat, M. Shafie, N.S. Shah, P.A. Shah, S.M. Shah, S. Shahabi, A. Shahbandi, I. Shahid, S. Shahid, W. Shahid, H.R. Shahsavari, M.J. Shahwan, A. Shaikh, M.A. Shaikh, A. Shakeri, A.S. Shalash, S. Sham, M.A. Shamim, M. Shams-Beyranvand, H. Shamshad, M.A. Shamsi, M. Shanawaz, A. Shankar, S. Sharfaei, A. Sharifan, J. Sharifi-Rad, R. Sharma, S. Sharma, U. Sharma, V. Sharma, R.P. Shastry, A. Shavandi, M. Shayan, A.M.E. Shehabeldine, A. Sheikh, R.A. Sheikhi, J. Shen, A. Shetty, B.S.K. Shetty, P.H. Shetty, P. Shi, K. Shibuya, D. Shiferaw, M. Shigematsu, M.-J. Shin, Y.H. Shin, R. Shiri, R. Shirkoohi, N.A. Shitaye, A. Shittu, I. Shiue, K.M. Shivakumar, V. Shivarov, F. Shokraneh, A. Shokri, S. Shool, S.A. Shorofi, S. Shrestha, K. Shuval, E.E. Siddig, J.P. Silva, L.M.L.R. Silva, S. Silva, C.R. Simpson, A. Singal, A. Singh, B.B. Singh, G. Singh, J. Singh, N.P. Singh, P. Singh, S. Singh, D.N. Sinha, R. Sinto, M.S. Siraj, S.B. Sirota, F. Sitas, S. Sivakumar, V.Y. Skryabin, A.A. Skryabina, D.A. Sleet, B. Socea, A. Sokhan, R. Solanki, S. Solanki, H. Soleimani, S.S.M. Soliman, S. Song, Y. Song, R.J.D. Sorensen, J.B. Soriano, I.N. Soyiri, M. Spartalis, S. Spearman, C.T. Sreeramareddy, V.K. Srivastava, J.D. Stanaway, M.H. Stanikzai, B.A. Stark, J.R. Starnes, A.V. Starodubova, C. Stein, D.J. Stein, F. Steinbeis, C. Steiner, J.D. Steinmetz, P. Steiropoulos, A. Stevanovi\u0107, L. Stockfelt, M.A. Stokes, S. Stortecky, V. Subramaniyan, M. Suleman, R. Suliankatchi Abdulkader, A. Sultana, H.Z. Sun, J. Sun, J. Sundstr\u00f6m, D. Sunkersing, K.S. Sunnerhagen, C.K. Swain, L. Szarpak, M.D. Szeto, M. Sz\u00f3cska, P. Tabaee Damavandi, R. Tabar\u00e9s-Seisdedos, S.M. Tabatabaei, O. Tabatabaei Malazy, S.-A. Tabatabaeizadeh, S. Tabatabai, M. Tabish, J. Tadakamadla, S.K. Tadakamadla, Y. Taheri Abkenar, M. Taheri Soodejani, J. Taiba, K. Takahashi, I.M. Talaat, A. Talukder, M. Tampa, J.L. Tamuzi, K.-K. Tan, S. Tandukar, H. Tang, H.K. Tang, I.U. Tarigan, M.K. Tariku, M. Tariqujjaman, E.E. Tarkang, R. Tavakoli Oliaee, S.M. Tavangar, N. Taveira, Y.M. Tefera, M.-H. Temsah, R.M.H. Temsah, M. Teramoto, R. Tesler, E. Teye-Kwadjo, R. Thakur, P. Thangaraju, K.R. Thankappan, S. Tharwat, R. Thayakaran, N. Thomas, N.K. Thomas, A.M. Thomson, A.G. Thrift, C.C.C. Thum, L.C. Thygesen, J. Tian, A. Tichopad, J.H.V. Ticoalu, T. Tillawi, T.Y. Tiruye, M.V. Titova, M. Tonelli, R. Topor-Madry, A.T. Toriola, A.E. Torre, M. Touvier, M.R. Tovani-Palone, J.T. Tran, N.M. Tran, D. Trico, S.J. Tromans, T.T.T.T. Truyen, A. Tsatsakis, G.M. Tsegay, E.E. Tsermpini, M. Tumurkhuu, K. Tung, S. Tyrovolas, S.M.N. Uddin, A.J. Udoakang, A. Udoh, A. Ullah, I. Ullah, S. Ullah, S. Ullah, S. Umakanthan, C.D. Umeokonkwo, B. Unim, B. Unnikrishnan, C.A. Unsworth, E. Upadhyay, D. Urso, J.S. Usman, S.M. Vahabi, A.G. Vaithinathan, R. Valizadeh, S.M. Van de Velde, J. Van den Eynde, O. Varga, P. Vart, S.B. Varthya, T.J. Vasankari, M. Vasic, S. Vaziri, B. Vellingiri, N. Venketasubramanian, N.A. Verghese, M. Verma, M. Veroux, G.-I. Verras, D. Vervoort, J.H. Villafa\u00f1e, G.I. Villanueva, M. Vinayak, F.S. Violante, M. Viskadourou, S.K. Vladimirov, V. Vlassov, B. Vo, S.E. Vollset, A. Vongpradith, T. Vos, I.S. Vujcic, R. Vukovic, H.A. Wafa, Y. Waheed, R.G. Wamai, C. Wang, N. Wang, S. Wang, S. Wang, Y. Wang, Y.-P. Wang, M. Waqas, P. Ward, E.G. Wassie, S. Watson, S.L.W. Watson, K.G. Weerakoon, M.Y. Wei, R.G. Weintraub, D.J. Weiss, R. Westerman, J.L. Whisnant, T. Wiangkham, D.P. Wickramasinghe, N.D. Wickramasinghe, A. Wilandika, C. Wilkerson, P. Willeit, S. Wilson, M.W. Wojewodzic, D.H. Woldegebreal, A.W. Wolf, C.D.A. Wolfe, Y.A. Wondimagegene, Y.J. Wong, U. Wongsin, A.-M. Wu, C. Wu, F. Wu, X. Wu, Z. Wu, J. Xia, H. Xiao, Y. Xie, S. Xu, W.-D. Xu, X. Xu, Y.Y. Xu, A. Yadollahpour, K. Yamagishi, D. Yang, L. Yang, Y. Yano, Y. Yao, H. Yaribeygi, P. Ye, S.S. Yehualashet, M. Yesiltepe, S.A. Yesuf, S. Yezli, S. Yi, A. Yigezu, A. Yi\u011fit, V. Yi\u011fit, P. Yip, M.B. Yismaw, Y. Yismaw, D.K. Yon, N. Yonemoto, S.-J. Yoon, Y. You, M.Z. Younis, Z. Yousefi, C. Yu, Y. Yu, F.H. Yuh, S. Zadey, V. Zadnik, N. Zafari, F. Zakham, N. Zaki, S.B. Zaman, N. Zamora, R. Zand, M. Zangiabadian, H.J. Zar, I. Zare, A. Zarrintan, M.G.M. Zeariya, Z. Zeinali, H. Zhang, J. Zhang, J. Zhang, L. Zhang, Y. Zhang, Z.-J. Zhang, H. Zhao, C. Zhong, J. Zhou, B. Zhu, L. Zhu, M. Ziafati, M. Zieli\u0144ska, O.A. Zitoun, M. Zoladl, Z. Zou, L.J. Zuhlke, A. Zumla, E. Zweck, S.H. Zyoud, E.E. Wool, C.J.L. Murray, Global burden of 288 causes of death and life expectancy decomposition in 204 countries and territories and 811 subnational locations, 1990\u20132021: a systematic analysis for the Global Burden of Disease Study 2021, The Lancet, 403 (2024) 2100\u20132132."},{"key":"10.1016\/j.jconrel.2026.115091_bb0020","doi-asserted-by":"crossref","first-page":"200","DOI":"10.1016\/S0140-6736(19)32989-7","article-title":"Global, regional, and national sepsis incidence and mortality, 1990\u20132017: analysis for the global burden of disease study","volume":"395","author":"Rudd","year":"2020","journal-title":"The Lancet"},{"key":"10.1016\/j.jconrel.2026.115091_bb0025","doi-asserted-by":"crossref","first-page":"2921","DOI":"10.1158\/0008-5472.CAN-25-0999","article-title":"Epigenetic heritability of cell plasticity drives cancer drug resistance through a one-to-many genotype-to-phenotype paradigm","volume":"85","author":"Oliveira","year":"2025","journal-title":"Cancer Res."},{"key":"10.1016\/j.jconrel.2026.115091_bb0030","doi-asserted-by":"crossref","first-page":"629","DOI":"10.1016\/S0140-6736(21)02724-0","article-title":"Global burden of bacterial antimicrobial resistance in 2019: A systematic analysis","volume":"399","author":"Murray","year":"2022","journal-title":"The Lancet"},{"key":"10.1016\/j.jconrel.2026.115091_bb0035","doi-asserted-by":"crossref","first-page":"323","DOI":"10.1111\/aji.12412","article-title":"Microbicide trials network biomedical sciences working group and the MTN 004 protocol team, soluble immune mediators and vaginal Bacteria impact innate genital mucosal antimicrobial activity in Young women","volume":"74","author":"Madan","year":"2015","journal-title":"Am. J. Reprod. Immunol."},{"key":"10.1016\/j.jconrel.2026.115091_bb0040","doi-asserted-by":"crossref","first-page":"1451","DOI":"10.1016\/j.addr.2005.04.002","article-title":"Bacterial resistance to antibiotics: enzymatic degradation and modification","volume":"57","author":"Wright","year":"2005","journal-title":"Adv. Drug Deliv. Rev."},{"key":"10.1016\/j.jconrel.2026.115091_bb0045","article-title":"MDR pumps as crossroads of resistance: antibiotics and bacteriophages","volume":"11","author":"Nazarov","year":"2022","journal-title":"Antibiotics-Basel"},{"key":"10.1016\/j.jconrel.2026.115091_bb0050","doi-asserted-by":"crossref","first-page":"280","DOI":"10.1038\/s41579-022-00820-y","article-title":"Molecular mechanisms of antibiotic resistance revisited","volume":"21","author":"Darby","year":"2022","journal-title":"Nat. Rev. Microbiol."},{"key":"10.1016\/j.jconrel.2026.115091_bb0055","doi-asserted-by":"crossref","first-page":"43","DOI":"10.1016\/j.bcp.2016.10.005","article-title":"Antibiotics: pharmacokinetics, toxicity, resistance and multidrug efflux pumps","volume":"133","author":"Y\u0131lmaz","year":"2017","journal-title":"Biochem. Pharmacol."},{"key":"10.1016\/j.jconrel.2026.115091_bb0060","doi-asserted-by":"crossref","first-page":"757","DOI":"10.1016\/j.chom.2017.10.020","article-title":"Antibiotic-induced changes to the host metabolic environment inhibit drug efficacy and alter immune function","volume":"22","author":"Yang","year":"2017","journal-title":"Cell Host Microbe"},{"key":"10.1016\/j.jconrel.2026.115091_bb0065","doi-asserted-by":"crossref","first-page":"1015","DOI":"10.1111\/raq.12511","article-title":"A global analysis on the systemic effects of antibiotics in cultured fish and their potential human health risk: a review","volume":"13","author":"Limbu","year":"2020","journal-title":"Rev. Aquac."},{"key":"10.1016\/j.jconrel.2026.115091_bb0070","doi-asserted-by":"crossref","first-page":"18","DOI":"10.1016\/j.chom.2024.05.008","article-title":"Epithelial hypoxia maintains colonization resistance against Candida albicans","volume":"32","author":"Savage","year":"2024","journal-title":"Cell Host Microbe"},{"key":"10.1016\/j.jconrel.2026.115091_bb0075","doi-asserted-by":"crossref","first-page":"15","DOI":"10.1126\/scitranslmed.aao4755","article-title":"Antibiotics induce sustained dysregulation of intestinal T cell immunity by perturbing macrophage homeostasis","volume":"10","author":"Scott","year":"2018","journal-title":"Sci. Transl. Med."},{"key":"10.1016\/j.jconrel.2026.115091_bb0080","doi-asserted-by":"crossref","DOI":"10.1080\/19490976.2020.1870402","article-title":"Association between antibiotics and gut microbiome dysbiosis in children: systematic review and meta-analysis","volume":"13","author":"McDonnell","year":"2021","journal-title":"Gut Microbes"},{"key":"10.1016\/j.jconrel.2026.115091_bb0085","doi-asserted-by":"crossref","DOI":"10.34133\/research.0867","article-title":"Gut Commensal antibiotic-resistant Parabacteroides goldsteinii ameliorates mouse colitis through valine\u2013isobutyrate metabolism","volume":"8","author":"He","year":"2025","journal-title":"Research"},{"key":"10.1016\/j.jconrel.2026.115091_bb0090","doi-asserted-by":"crossref","first-page":"1210","DOI":"10.1016\/j.biotechadv.2016.08.003","article-title":"The gut microbiota: a treasure for human health","volume":"34","author":"Li","year":"2016","journal-title":"Biotechnol. Adv."},{"key":"10.1016\/j.jconrel.2026.115091_bb0095","doi-asserted-by":"crossref","DOI":"10.1038\/nrdp.2016.20","article-title":"Clostridium difficile infection","volume":"2","author":"Smits","year":"2016","journal-title":"Nat. Rev. Dis. Primers."},{"key":"10.1016\/j.jconrel.2026.115091_bb0100","doi-asserted-by":"crossref","first-page":"500","DOI":"10.1038\/s41385-020-00338-7","article-title":"Obeticholic acid ameliorates severity of Clostridioides difficile infection in high fat diet-induced obese mice","volume":"14","author":"Jose","year":"2021","journal-title":"Mucosal Immunol."},{"key":"10.1016\/j.jconrel.2026.115091_bb0105","doi-asserted-by":"crossref","first-page":"1320","DOI":"10.1056\/NEJMoa1910215","article-title":"Trends in U.S. Burden of Clostridioides difficile infection and outcomes","volume":"382","author":"Guh","year":"2020","journal-title":"N. Engl. J. Med."},{"key":"10.1016\/j.jconrel.2026.115091_bb0110","doi-asserted-by":"crossref","DOI":"10.1038\/s41572-024-00503-3","article-title":"Invasive candidiasis","volume":"10","author":"Lass-Fl\u00f6rl","year":"2024","journal-title":"Nat. Rev. Dis. Primers."},{"key":"10.1016\/j.jconrel.2026.115091_bb0115","doi-asserted-by":"crossref","first-page":"328","DOI":"10.1016\/j.intimp.2018.10.021","article-title":"Antibiotics and autoimmune and allergy diseases: causative factor or treatment?","volume":"65","author":"Strzepa","year":"2018","journal-title":"Int. Immunopharmacol."},{"key":"10.1016\/j.jconrel.2026.115091_bb0120","doi-asserted-by":"crossref","first-page":"765","DOI":"10.1016\/j.chom.2021.02.021","article-title":"Developmental trajectory of the healthy human gut microbiota during the first 5 years of life","volume":"29","author":"Roswall","year":"2021","journal-title":"Cell Host Microbe"},{"key":"10.1016\/j.jconrel.2026.115091_bb0125","doi-asserted-by":"crossref","first-page":"735","DOI":"10.1086\/591126","article-title":"Emergency department visits for antibiotic-associated adverse events","volume":"47","author":"Shehab","year":"2008","journal-title":"Clin. Infect. Dis."},{"key":"10.1016\/j.jconrel.2026.115091_bb0130","doi-asserted-by":"crossref","first-page":"33","DOI":"10.1038\/ki.2010.337","article-title":"New insights into the mechanism of aminoglycoside nephrotoxicity: an integrative point of view","volume":"79","author":"Lopez-Novoa","year":"2011","journal-title":"Kidney Int."},{"key":"10.1016\/j.jconrel.2026.115091_bb0135","doi-asserted-by":"crossref","first-page":"878","DOI":"10.14309\/ajg.0000000000001259","article-title":"ACG clinical guideline: diagnosis and management of idiosyncratic drug-induced liver injury","volume":"116","author":"Chalasani","year":"2021","journal-title":"Am. J. Gastroenterol."},{"key":"10.1016\/j.jconrel.2026.115091_bb0140","doi-asserted-by":"crossref","first-page":"887","DOI":"10.1002\/hep.27912","article-title":"Characterization of amoxicillin- and clavulanic acid-specific T cells in patients with amoxicillin-clavulanate-induced liver injury","volume":"62","author":"Kim","year":"2015","journal-title":"Hepatology"},{"key":"10.1016\/j.jconrel.2026.115091_bb0145","doi-asserted-by":"crossref","first-page":"8","DOI":"10.3389\/fncel.2021.692762","article-title":"Mechanism and prevention of ototoxicity induced by aminoglycosides","volume":"15","author":"Fu","year":"2021","journal-title":"Front. Cell. Neurosci."},{"key":"10.1016\/j.jconrel.2026.115091_bb0150","doi-asserted-by":"crossref","DOI":"10.3389\/fncel.2021.692762","article-title":"Mechanism and prevention of ototoxicity induced by aminoglycosides","volume":"15","author":"Fu","year":"2021","journal-title":"Front. Cell. Neurosci."},{"key":"10.1016\/j.jconrel.2026.115091_bb0155","doi-asserted-by":"crossref","first-page":"37","DOI":"10.2165\/00003495-199958002-00007","article-title":"Toxicity of quinolones","volume":"58","author":"Stahlmann","year":"1999","journal-title":"Drugs"},{"key":"10.1016\/j.jconrel.2026.115091_bb0160","article-title":"Evaluation and management of penicillin allergy","volume":"321","author":"Shenoy","year":"2019","journal-title":"Jama"},{"key":"10.1016\/j.jconrel.2026.115091_bb0165","doi-asserted-by":"crossref","DOI":"10.1007\/s00431-025-05975-3","article-title":"Periorificial dermatitis in infants and preschoolers \u2013 a narrative review","volume":"184","author":"Chiriac","year":"2025","journal-title":"Eur. J. Pediatr."},{"key":"10.1016\/j.jconrel.2026.115091_bb0170","doi-asserted-by":"crossref","DOI":"10.1542\/peds.2016-2706","article-title":"The use of systemic and topical fluoroquinolones","volume":"138","author":"Jackson","year":"2016","journal-title":"Pediatrics"},{"key":"10.1016\/j.jconrel.2026.115091_bb0175","doi-asserted-by":"crossref","first-page":"1597","DOI":"10.2215\/CJN.03750319","article-title":"Estimated glomerular filtration rate decline and incident frailty in older adults","volume":"14","author":"Guerville","year":"2019","journal-title":"Clin. J. Am. Soc. Nephrol."},{"key":"10.1016\/j.jconrel.2026.115091_bb0180","doi-asserted-by":"crossref","first-page":"1082","DOI":"10.1126\/science.aax3879","article-title":"The evolution of antibiotic resistance","volume":"365","author":"MacLean","year":"2019","journal-title":"Science"},{"key":"10.1016\/j.jconrel.2026.115091_bb0185","doi-asserted-by":"crossref","first-page":"6600","DOI":"10.1002\/anie.201506818","article-title":"Targeting antibiotic resistance","volume":"55","author":"Chellat","year":"2016","journal-title":"Angew. Chem. Int. Ed."},{"key":"10.1016\/j.jconrel.2026.115091_bb0190","doi-asserted-by":"crossref","first-page":"633","DOI":"10.1302\/2058-5241.4.180095","article-title":"Implant materials and prosthetic joint infection: the battle with the biofilm","volume":"4","author":"Davidson","year":"2019","journal-title":"EFORT Open Rev."},{"key":"10.1016\/j.jconrel.2026.115091_bb0195","doi-asserted-by":"crossref","first-page":"71","DOI":"10.1016\/j.jgar.2013.03.002","article-title":"Central venous catheter-related biofilm infections: An up-to-date focus on meticillin-resistant Staphylococcus aureus","volume":"1","author":"Esposito","year":"2013","journal-title":"J. Global Antimicrob. Resist."},{"key":"10.1016\/j.jconrel.2026.115091_bb0200","doi-asserted-by":"crossref","first-page":"559","DOI":"10.1016\/j.actbio.2025.06.053","article-title":"Biofilm penetrating and disrupting polymers to effectively treat endotracheal-tube-associated biofilm infections","volume":"202","author":"Yu","year":"2025","journal-title":"Acta Biomater."},{"key":"10.1016\/j.jconrel.2026.115091_bb0205","doi-asserted-by":"crossref","first-page":"5478","DOI":"10.1007\/s12010-022-03964-y","article-title":"Burn wounds: proliferating site for biofilm infection","volume":"195","author":"Wang","year":"2023","journal-title":"Appl. Biochem. Biotechnol."},{"key":"10.1016\/j.jconrel.2026.115091_bb0210","doi-asserted-by":"crossref","first-page":"563","DOI":"10.1038\/nrmicro.2016.94","article-title":"Biofilms: an emergent form of bacterial life","volume":"14","author":"Flemming","year":"2016","journal-title":"Nat. Rev. Microbiol."},{"key":"10.1016\/j.jconrel.2026.115091_bb0215","doi-asserted-by":"crossref","first-page":"95","DOI":"10.1038\/nrmicro821","article-title":"Bacterial biofilms: from the natural environment to infectious diseases","volume":"2","author":"Hall-Stoodley","year":"2004","journal-title":"Nat. Rev. Microbiol."},{"key":"10.1016\/j.jconrel.2026.115091_bb0220","first-page":"12","article-title":"Biofilm formation of Candida albicans facilitates fungal infiltration and persister cell formation in vaginal candidiasis","volume":"11","author":"Wu","year":"2020","journal-title":"Front. Microbiol."},{"key":"10.1016\/j.jconrel.2026.115091_bb0225","doi-asserted-by":"crossref","first-page":"167","DOI":"10.1128\/CMR.15.2.167-193.2002","article-title":"Biofilms: survival mechanisms of clinically relevant microorganisms","volume":"15","author":"Donlan","year":"2002","journal-title":"Clin. Microbiol. Rev."},{"key":"10.1016\/j.jconrel.2026.115091_bb0230","doi-asserted-by":"crossref","first-page":"5","DOI":"10.1111\/j.1600-065X.2010.01001.x","article-title":"Intracellular pathogens: living in an extreme environment","volume":"240","author":"Kaufmann","year":"2011","journal-title":"Immunol. Rev."},{"key":"10.1016\/j.jconrel.2026.115091_bb0235","doi-asserted-by":"crossref","first-page":"100","DOI":"10.1007\/BF01964420","article-title":"Intracellular-distribution and activity of antibiotics","volume":"10","author":"Tulkens","year":"1991","journal-title":"Eur. J. Clin. Microbiol. Infect. Dis."},{"key":"10.1016\/j.jconrel.2026.115091_bb0240","doi-asserted-by":"crossref","first-page":"S216","DOI":"10.1007\/BF01644037","article-title":"Activity of intracellular antibiotics","volume":"19","author":"Vanderauwera","year":"1991","journal-title":"Infection"},{"key":"10.1016\/j.jconrel.2026.115091_bb0245","doi-asserted-by":"crossref","first-page":"3","DOI":"10.1602\/neurorx.2.1.3","article-title":"The blood-brain barrier: bottleneck in brain drug development","volume":"2","author":"Pardridge","year":"2005","journal-title":"NeuroRX"},{"key":"10.1016\/j.jconrel.2026.115091_bb0250","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1159\/000094668","article-title":"Principles of antibiotic penetration into abscess fluid","volume":"78","author":"Wagner","year":"2006","journal-title":"Pharmacology"},{"key":"10.1016\/j.jconrel.2026.115091_bb0255","doi-asserted-by":"crossref","first-page":"e216","DOI":"10.1016\/S1473-3099(20)30327-3","article-title":"The value of antimicrobial peptides in the age of resistance","volume":"20","author":"Magana","year":"2020","journal-title":"Lancet Infect. Dis."},{"key":"10.1016\/j.jconrel.2026.115091_bb0260","doi-asserted-by":"crossref","first-page":"3959","DOI":"10.1021\/jacs.9b12936","article-title":"Phage-guided targeting, discriminative imaging, and synergistic killing of bacteria by AIE bioconjugates","volume":"142","author":"He","year":"2020","journal-title":"J. Am. Chem. Soc."},{"key":"10.1016\/j.jconrel.2026.115091_bb0265","doi-asserted-by":"crossref","DOI":"10.1002\/adhm.201900608","article-title":"Rejuvenated photodynamic therapy for bacterial infections","volume":"8","author":"Jia","year":"2019","journal-title":"Adv. Healthc. Mater."},{"key":"10.1016\/j.jconrel.2026.115091_bb0270","doi-asserted-by":"crossref","first-page":"2000","DOI":"10.1002\/med.21572","article-title":"Phage therapy: what factors shape phage pharmacokinetics and bioavailability? Systematic and critical review","volume":"39","author":"D\u0105browska","year":"2019","journal-title":"Med. Res. Rev."},{"key":"10.1016\/j.jconrel.2026.115091_bb0275","doi-asserted-by":"crossref","DOI":"10.1128\/MMBR.00012-19","article-title":"Pharmacologically aware phage therapy: pharmacodynamic and pharmacokinetic obstacles to phage antibacterial action in animal and human bodies","volume":"83","author":"D\u0105browska","year":"2019","journal-title":"Microbiol. Mol. Biol. Rev."},{"key":"10.1016\/j.jconrel.2026.115091_bb0280","doi-asserted-by":"crossref","DOI":"10.3389\/fcimb.2018.00376","article-title":"Bacteriophage therapy: clinical trials and regulatory hurdles","volume":"8","author":"Furfaro","year":"2018","journal-title":"Front. Cell. Infect. Microbiol."},{"key":"10.1016\/j.jconrel.2026.115091_bb0285","doi-asserted-by":"crossref","DOI":"10.1016\/j.addr.2024.115472","article-title":"A systematic overview of strategies for photosensitizer and light delivery in antibacterial photodynamic therapy for lung infections","volume":"215","author":"Shleeva","year":"2024","journal-title":"Adv. Drug Deliv. Rev."},{"key":"10.1016\/j.jconrel.2026.115091_bb0290","doi-asserted-by":"crossref","DOI":"10.3390\/biomedicines9010069","article-title":"Recent advances in photodynamic therapy for deep-seated tumors with the aid of nanomedicine","volume":"9","author":"Li","year":"2021","journal-title":"Biomedicines"},{"key":"10.1016\/j.jconrel.2026.115091_bb0295","doi-asserted-by":"crossref","first-page":"255","DOI":"10.1097\/QCO.0000000000000721","article-title":"Antimicrobial use in central nervous system infections","volume":"34","author":"Ciummo","year":"2021","journal-title":"Curr. Opin. Infect. Dis."},{"key":"10.1016\/j.jconrel.2026.115091_bb0300","doi-asserted-by":"crossref","first-page":"531","DOI":"10.1016\/j.jconrel.2014.03.050","article-title":"Cell-mediated delivery of nanoparticles: taking advantage of circulatory cells to target nanoparticles","volume":"190","author":"Anselmo","year":"2014","journal-title":"J. Control. 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Microbiol."},{"key":"10.1016\/j.jconrel.2026.115091_bb0370","doi-asserted-by":"crossref","first-page":"958","DOI":"10.1038\/nri2448","article-title":"Exploring the full spectrum of macrophage activation","volume":"8","author":"Mosser","year":"2008","journal-title":"Nat. Rev. Immunol."},{"key":"10.1016\/j.jconrel.2026.115091_bb0375","doi-asserted-by":"crossref","first-page":"159","DOI":"10.1038\/nri3399","article-title":"Neutrophil recruitment and function in health and inflammation","volume":"13","author":"Kolaczkowska","year":"2013","journal-title":"Nat. Rev. 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Microbiol."},{"key":"10.1016\/j.jconrel.2026.115091_bb0420","first-page":"22","article-title":"TLR-activated mesenchymal stromal cell therapy and antibiotics to treat multi-drug resistant staphylococcal septic arthritis in an equine model","author":"Pezzanite","year":"2022","journal-title":"Ann. Transl. 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Lett."},{"key":"10.1016\/j.jconrel.2026.115091_bb0465","doi-asserted-by":"crossref","first-page":"149","DOI":"10.1111\/j.1365-2249.2009.03874.x","article-title":"Cell contact, prostaglandin E2 and transforming growth factor beta 1 play non-redundant roles in human mesenchymal stem cell induction of CD4+CD25Highforkhead box P3+ regulatory T cells","volume":"156","author":"English","year":"2009","journal-title":"Clin. Exp. Immunol."},{"key":"10.1016\/j.jconrel.2026.115091_bb0470","doi-asserted-by":"crossref","first-page":"L1003","DOI":"10.1152\/ajplung.00180.2011","article-title":"Human mesenchymal stem cells reduce mortality and bacteremia in gram-negative sepsis in mice in part by enhancing the phagocytic activity of blood monocytes","volume":"302","author":"Krasnodembskaya","year":"2012","journal-title":"Am. J. Physiol.-Lung Cell. Mol. Physiol."},{"key":"10.1016\/j.jconrel.2026.115091_bb0475","doi-asserted-by":"crossref","first-page":"10","DOI":"10.1186\/1465-9921-15-39","article-title":"Treatment of acute respiratory distress syndrome with allogeneic adipose-derived mesenchymal stem cells: a randomized, placebo-controlled pilot study","volume":"15","author":"Zheng","year":"2014","journal-title":"Respir. Res."},{"key":"10.1016\/j.jconrel.2026.115091_bb0480","doi-asserted-by":"crossref","first-page":"14","DOI":"10.1183\/13993003.02021-2017","article-title":"Mesenchymal stem cells enhance NOX2-dependent reactive oxygen species production and bacterial killing in macrophages during sepsis","volume":"51","author":"Rabani","year":"2018","journal-title":"Eur. Respir. J."},{"key":"10.1016\/j.jconrel.2026.115091_bb0485","doi-asserted-by":"crossref","first-page":"24","DOI":"10.1186\/s40635-018-0194-1","article-title":"Clinical-grade mesenchymal stem cells derived from umbilical cord improve septic shock in pigs","volume":"6","author":"Laroye","year":"2018","journal-title":"Intensive Care Med. 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Target. Ther."},{"key":"10.1016\/j.jconrel.2026.115091_bb0530","doi-asserted-by":"crossref","DOI":"10.3389\/fimmu.2021.636818","article-title":"Marginal zone B cells assist with neutrophil accumulation to fight against systemic Staphylococcus aureus infection","volume":"12","author":"Lo","year":"2021","journal-title":"Front. Immunol."},{"key":"10.1016\/j.jconrel.2026.115091_bb0535","doi-asserted-by":"crossref","DOI":"10.1084\/jem.20190502","article-title":"Anti\u2013IFN-\u03b3 autoantibodies underlie disseminatedTalaromyces marneffeiinfections","volume":"217","author":"Guo","year":"2020","journal-title":"J. Exp. Med."},{"key":"10.1016\/j.jconrel.2026.115091_bb0540","doi-asserted-by":"crossref","first-page":"14","DOI":"10.1126\/sciimmunol.adm8186","article-title":"Chimeric autoantibody receptor T cells clonally eliminate B cells producing autoantibodies against IFN-\u03b3","volume":"10","author":"Peng","year":"2025","journal-title":"Sci. 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Chem."},{"key":"10.1016\/j.jconrel.2026.115091_bb0585","doi-asserted-by":"crossref","first-page":"541","DOI":"10.1042\/BSR20130014","article-title":"Metal ions in macrophage antimicrobial pathways: emerging roles for zinc and copper","volume":"33","author":"Stafford","year":"2013","journal-title":"Biosci. Rep."},{"key":"10.1016\/j.jconrel.2026.115091_bb0590","doi-asserted-by":"crossref","first-page":"18954","DOI":"10.1074\/jbc.R115.647099","article-title":"The role of copper and zinc toxicity in innate immune defense against bacterial pathogens","volume":"290","author":"Djoko","year":"2015","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.jconrel.2026.115091_bb0595","doi-asserted-by":"crossref","first-page":"6341","DOI":"10.1073\/pnas.1820870116","article-title":"Uropathogenic Escherichia coli employs both evasion and resistance to subvert innate immune-mediated zinc toxicity for dissemination","volume":"116","author":"Stocks","year":"2019","journal-title":"Proc. Natl. Acad. Sci. U. S. A."},{"key":"10.1016\/j.jconrel.2026.115091_bb0600","doi-asserted-by":"crossref","first-page":"1901","DOI":"10.1096\/fj.201500061","article-title":"Salmonella employs multiple mechanisms to subvert the TLR-inducible zinc-mediated antimicrobial response of human macrophages","volume":"30","author":"Kapetanovic","year":"2016","journal-title":"FASEB J."},{"key":"10.1016\/j.jconrel.2026.115091_bb0605","doi-asserted-by":"crossref","first-page":"1724","DOI":"10.1161\/ATVBAHA.119.312463","article-title":"Neutrophil extracellular traps","volume":"39","author":"Th\u00e5lin","year":"2019","journal-title":"Arterioscler. Thromb. Vasc. 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Med."},{"key":"10.1016\/j.jconrel.2026.115091_bb0705","doi-asserted-by":"crossref","DOI":"10.1038\/nrdp.2016.45","article-title":"Sepsis and septic shock","volume":"2","author":"Hotchkiss","year":"2016","journal-title":"Nat. Rev. Dis. Primers."},{"key":"10.1016\/j.jconrel.2026.115091_bb0710","doi-asserted-by":"crossref","first-page":"62","DOI":"10.1126\/science.aaa4967","article-title":"Adoptive cell transfer as personalized immunotherapy for human cancer","volume":"348","author":"Rosenberg","year":"2015","journal-title":"Science"},{"key":"10.1016\/j.jconrel.2026.115091_bb0715","doi-asserted-by":"crossref","first-page":"346","DOI":"10.1038\/nbt.4086","article-title":"IL-7 and CCL19 expression in CAR-T cells improves immune cell infiltration and CAR-T cell survival in the tumor","volume":"36","author":"Adachi","year":"2018","journal-title":"Nat. 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Bioeng."},{"key":"10.1016\/j.jconrel.2026.115091_bb0750","doi-asserted-by":"crossref","DOI":"10.1016\/j.biomaterials.2025.123116","article-title":"Inhibition of PDT-induced PGE2 surge for enhanced photo-immunotherapy","volume":"317","author":"Liu","year":"2025","journal-title":"Biomaterials"},{"key":"10.1016\/j.jconrel.2026.115091_bb0755","doi-asserted-by":"crossref","first-page":"7","DOI":"10.1073\/pnas.2218973120","article-title":"Metallacage- based enhanced PDT strategy for bacterial elimination via inhibiting endogenous NO production","volume":"120","author":"Huang","year":"2023","journal-title":"Proc. Natl. Acad. Sci. U. S. A."},{"key":"10.1016\/j.jconrel.2026.115091_bb0760","article-title":"Non-invasive photodynamic therapy against -periodontitis-causing bacteria","volume":"9","author":"Park","year":"2019","journal-title":"Sci. Rep."},{"key":"10.1016\/j.jconrel.2026.115091_bb0765","doi-asserted-by":"crossref","DOI":"10.1002\/adma.202414111","article-title":"Elaborated bio-heterojunction with robust sterilization effect for infected tissue regeneration via activating competent cell-like antibacterial tactic","volume":"36","author":"Huang","year":"2024","journal-title":"Adv. Mater."},{"key":"10.1016\/j.jconrel.2026.115091_bb0770","doi-asserted-by":"crossref","DOI":"10.1016\/j.biomaterials.2022.121875","article-title":"Advanced techniques for performing photodynamic therapy in deep-seated tissues","volume":"291","author":"Sun","year":"2022","journal-title":"Biomaterials"},{"key":"10.1016\/j.jconrel.2026.115091_bb0775","article-title":"Adoptive macrophage directed photodynamic therapy of multidrug-resistant bacterial infection","volume":"14","author":"Wang","year":"2023","journal-title":"Nat. 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Dis."},{"key":"10.1016\/j.jconrel.2026.115091_bb0835","doi-asserted-by":"crossref","first-page":"138","DOI":"10.1056\/NEJMra021333","article-title":"The pathophysiology and treatment of sepsis","volume":"348","author":"Hotchkiss","year":"2003","journal-title":"N. Engl. J. Med."},{"key":"10.1016\/j.jconrel.2026.115091_bb0840","doi-asserted-by":"crossref","first-page":"2594","DOI":"10.1001\/jama.2011.1829","article-title":"Immunosuppression in patients who die of sepsis and multiple organ failure","volume":"306","author":"Boomer","year":"2011","journal-title":"Jama \u2013 J. Am. Med. Assoc."},{"key":"10.1016\/j.jconrel.2026.115091_bb0845","doi-asserted-by":"crossref","first-page":"862","DOI":"10.1038\/nri3552","article-title":"Sepsis-induced immunosuppression: from cellular dysfunctions to immunotherapy","volume":"13","author":"Hotchkiss","year":"2013","journal-title":"Nat. Rev. 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(Larchmt.)"},{"key":"10.1016\/j.jconrel.2026.115091_bb0865","doi-asserted-by":"crossref","first-page":"138","DOI":"10.1164\/rccm.2009005","article-title":"A randomized phase II trial of granulocyte-macrophage colony-stimulating factor therapy in severe sepsis with respiratory dysfunction","volume":"166","author":"Presneill","year":"2002","journal-title":"Am. J. Respir. Crit. Care Med."},{"key":"10.1016\/j.jconrel.2026.115091_bb0870","doi-asserted-by":"crossref","first-page":"678","DOI":"10.1038\/nm0697-678","article-title":"Monocyte deactivation in septic patients: restoration by IFN-gamma treatment","volume":"3","author":"Docke","year":"1997","journal-title":"Nat. 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Part A"},{"key":"10.1016\/j.jconrel.2026.115091_bb1020","doi-asserted-by":"crossref","first-page":"457","DOI":"10.1038\/nmat2441","article-title":"Complexity in biomaterials for tissue engineering","volume":"8","author":"Place","year":"2009","journal-title":"Nat. Mater."},{"key":"10.1016\/j.jconrel.2026.115091_bb1025","doi-asserted-by":"crossref","DOI":"10.3389\/fbioe.2021.660145","article-title":"Hydrogel scaffolds to deliver cell therapies for wound healing","volume":"9","author":"Sivaraj","year":"2021","journal-title":"Front. Bioeng. Biotechnol."},{"key":"10.1016\/j.jconrel.2026.115091_bb1030","first-page":"19","article-title":"Trends in hydrogel-based encapsulation technologies for advanced cell therapies applied to limb ischemia","volume":"13","author":"Costa","year":"2022","journal-title":"Mater. 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Agents"},{"key":"10.1016\/j.jconrel.2026.115091_bb1150","doi-asserted-by":"crossref","first-page":"385","DOI":"10.1038\/s41579-022-00686-0","article-title":"Skeletal infections: microbial pathogenesis, immunity and clinical management","volume":"20","author":"Masters","year":"2022","journal-title":"Nat. Rev. Microbiol."},{"key":"10.1016\/j.jconrel.2026.115091_bb1155","article-title":"Nanomaterials against intracellular bacterial infection: from drug delivery to intrinsic biofunction","volume":"11","author":"Chen","year":"2023","journal-title":"Front. Bioeng. Biotechnol."},{"key":"10.1016\/j.jconrel.2026.115091_bb1160","doi-asserted-by":"crossref","DOI":"10.1016\/j.jconrel.2025.114204","article-title":"Nanotechnology-based approaches to tackle bacterial infections","volume":"387","author":"Savadi","year":"2025","journal-title":"J. Control. Release"},{"key":"10.1016\/j.jconrel.2026.115091_bb1165","doi-asserted-by":"crossref","DOI":"10.1002\/adma.202109789","article-title":"Cascade-targeting poly(amino acid) nanoparticles eliminate intracellular bacteria via on-site antibiotic delivery","volume":"34","author":"Feng","year":"2022","journal-title":"Adv. Mater."},{"key":"10.1016\/j.jconrel.2026.115091_bb1170","doi-asserted-by":"crossref","first-page":"820","DOI":"10.1016\/j.chom.2015.05.005","article-title":"Cyclic GMP-AMP synthase is an innate immune DNA sensor for Mycobacterium tuberculosis","volume":"17","author":"Collins","year":"2015","journal-title":"Cell Host Microbe"},{"key":"10.1016\/j.jconrel.2026.115091_bb1175","doi-asserted-by":"crossref","first-page":"471","DOI":"10.1016\/j.actbio.2025.03.002","article-title":"cGAS-mediated antibacterial immunotherapy against tuberculosis by macrophage-targeted manganese dioxide nanoagonist","volume":"196","author":"Liao","year":"2025","journal-title":"Acta Biomater."},{"key":"10.1016\/j.jconrel.2026.115091_bb1180","doi-asserted-by":"crossref","DOI":"10.1016\/j.phrs.2024.107379","article-title":"Macrophage targeted graphene oxide nanosystem synergize antibiotic killing and host immune defense for tuberculosis therapy","volume":"208","author":"Pi","year":"2024","journal-title":"Pharmacol. Res."},{"key":"10.1016\/j.jconrel.2026.115091_bb1185","doi-asserted-by":"crossref","first-page":"720","DOI":"10.1038\/s41594-023-01024-5","article-title":"Autophagy counteracts Mycobacterium tuberculosis infection at early stages","volume":"30","author":"Typas","year":"2023","journal-title":"Nat. Struct. Mol. Biol."},{"key":"10.1016\/j.jconrel.2026.115091_bb1190","doi-asserted-by":"crossref","DOI":"10.1371\/journal.ppat.1008294","article-title":"Mycobacterium abscessus infection leads to enhanced production of type 1 interferon and NLRP3 inflammasome activation in murine macrophages via mitochondrial oxidative stress","volume":"16","author":"Kim","year":"2020","journal-title":"PLoS Pathog."},{"key":"10.1016\/j.jconrel.2026.115091_bb1195","doi-asserted-by":"crossref","DOI":"10.1002\/advs.202511734","article-title":"Punicalagin enhances autophagy through Sirtuin 1\/FoxO3a axis to inhibit intracellular Mycobacterium Abscessus infection","volume":"13","author":"Bi","year":"2026","journal-title":"Adv. Sci."},{"key":"10.1016\/j.jconrel.2026.115091_bb1200","doi-asserted-by":"crossref","first-page":"2159","DOI":"10.4049\/jimmunol.1202348","article-title":"Targeting macrophage activation for the prevention and treatment of Staphylococcus aureus biofilm infections","volume":"190","author":"Hanke","year":"2013","journal-title":"J. Immunol."},{"key":"10.1016\/j.jconrel.2026.115091_bb1205","article-title":"Manganese-based biofunctional 2D nanosheets enabled in situ macrophage engineering for precise eradication of osteomyelitis","volume":"14","author":"Zhang","year":"2025","journal-title":"Adv. Healthc. Mater."},{"key":"10.1016\/j.jconrel.2026.115091_bb1210","article-title":"Neutrophil function conversion driven by immune switchpoint regulator against diabetes-related biofilm infections","volume":"36","author":"Guo","year":"2023","journal-title":"Adv. Mater."},{"key":"10.1016\/j.jconrel.2026.115091_bb1215","doi-asserted-by":"crossref","DOI":"10.1002\/adfm.202509454","article-title":"Oxygen-immunomodulated nanocatalysts enhance anti-infection by trained immunity","volume":"35","author":"Ruan","year":"2025","journal-title":"Adv. Funct. Mater."},{"key":"10.1016\/j.jconrel.2026.115091_bb1220","doi-asserted-by":"crossref","DOI":"10.1016\/j.jconrel.2025.114359","article-title":"Nano-strategy empowering trained immunity in vaccines","volume":"388","author":"Wang","year":"2025","journal-title":"J. Control. Release"},{"key":"10.1016\/j.jconrel.2026.115091_bb1225","doi-asserted-by":"crossref","first-page":"453","DOI":"10.4049\/jimmunol.1002213","article-title":"Hypoxia selectively inhibits respiratory burst activity and killing of Staphylococcus aureus in human neutrophils","volume":"186","author":"McGovern","year":"2011","journal-title":"J. Immunol."},{"key":"10.1016\/j.jconrel.2026.115091_bb1230","doi-asserted-by":"crossref","first-page":"166","DOI":"10.1016\/j.micinf.2016.10.005","article-title":"Hypoxic regulation of neutrophil function and consequences for Staphylococcus aureus infection","volume":"19","author":"Lodge","year":"2017","journal-title":"Microbes Infect."},{"key":"10.1016\/j.jconrel.2026.115091_bb1235","doi-asserted-by":"crossref","first-page":"1032","DOI":"10.1038\/s41565-024-01648-8","article-title":"Multimodal nanoimmunotherapy engages neutrophils to eliminate Staphylococcus aureus infections","volume":"19","author":"Zhu","year":"2024","journal-title":"Nat. Nanotechnol."},{"key":"10.1016\/j.jconrel.2026.115091_bb1240","doi-asserted-by":"crossref","first-page":"25","DOI":"10.1038\/s41551-024-01180-z","article-title":"Neutrophils bearing adhesive polymer micropatches as a drug-free cancer immunotherapy","volume":"8","author":"Kumbhojkar","year":"2024","journal-title":"Nat. Biomed. Eng."},{"key":"10.1016\/j.jconrel.2026.115091_bb1245","first-page":"15","article-title":"Piezoelectric-enhanced nanocatalysts trigger neutrophil N1 polarization against bacterial biofilm by disrupting redox homeostasis","volume":"37","author":"Ge","year":"2025","journal-title":"Adv. Mater."},{"key":"10.1016\/j.jconrel.2026.115091_bb1250","doi-asserted-by":"crossref","first-page":"484","DOI":"10.1038\/s41586-025-09278-3","article-title":"Neutrophils drive vascular occlusion, tumour necrosis and metastasis","volume":"645","author":"Adrover","year":"2025","journal-title":"Nature"},{"key":"10.1016\/j.jconrel.2026.115091_bb1255","doi-asserted-by":"crossref","first-page":"9868","DOI":"10.1021\/acsnano.4c14487","article-title":"Conductive hydrogel inspires neutrophil extracellular traps to combat bacterial infections in wounds","volume":"19","author":"OuYang","year":"2025","journal-title":"ACS Nano"},{"key":"10.1016\/j.jconrel.2026.115091_bb1260","doi-asserted-by":"crossref","first-page":"16726","DOI":"10.1021\/acsnano.4c01780","article-title":"Carbon dot-loaded apoptotic vesicles improve the liver Kupffer cell-mediated antibacterial effect to synergistically alleviate Sepsis","volume":"18","author":"Xiang","year":"2024","journal-title":"ACS Nano"},{"key":"10.1016\/j.jconrel.2026.115091_bb1265","doi-asserted-by":"crossref","DOI":"10.1002\/adhm.202501218","article-title":"Grancalcin hydrogel microneedle patches alleviate sepsis via modulation of calcium signaling to augment immune cell phagocytosis","volume":"14","author":"Xiang","year":"2025","journal-title":"Adv. Healthc. Mater."},{"key":"10.1016\/j.jconrel.2026.115091_bb1270","doi-asserted-by":"crossref","first-page":"17254","DOI":"10.1039\/C7NR06437C","article-title":"An apolipoprotein-enriched biomolecular corona switches the cellular uptake mechanism and trafficking pathway of lipid nanoparticles","volume":"9","author":"Digiacomo","year":"2017","journal-title":"Nanoscale"},{"key":"10.1016\/j.jconrel.2026.115091_bb1275","article-title":"Voluntary-opsonization-enabled precision nanomedicines for inflammation treatment","volume":"33","author":"Li","year":"2020","journal-title":"Adv. Mater."},{"key":"10.1016\/j.jconrel.2026.115091_bb1280","doi-asserted-by":"crossref","DOI":"10.1126\/scitranslmed.adu9186","article-title":"Neutrophil-mediated delivery of antibiotics across the tympanic membrane for otitis media treatment in a preclinical model","volume":"18","author":"Tang","year":"2026","journal-title":"Sci. Transl. Med."},{"key":"10.1016\/j.jconrel.2026.115091_bb1285","doi-asserted-by":"crossref","first-page":"11564","DOI":"10.1038\/s41467-025-67639-y","article-title":"Neutrophil-mediated delivery of hybrid cross-species nanovesicles for treatment of bacterial infections","volume":"16","author":"Li","year":"2025","journal-title":"Nat. Commun."},{"key":"10.1016\/j.jconrel.2026.115091_bb1290","doi-asserted-by":"crossref","first-page":"28866","DOI":"10.1021\/acsnano.4c09054","article-title":"Neutrophil hitchhiking enhances liposomal dexamethasone therapy of sepsis","volume":"18","author":"Mathur","year":"2024","journal-title":"ACS Nano"},{"key":"10.1016\/j.jconrel.2026.115091_bb1295","doi-asserted-by":"crossref","DOI":"10.1016\/j.nantod.2024.102414","article-title":"Engineering cells or cellular outer membranes as multifaceted vehicles for reinforcing nanomedicine-based pulmonary disease treatment","volume":"58","author":"Wang","year":"2024","journal-title":"Nano Today"},{"key":"10.1016\/j.jconrel.2026.115091_bb1300","doi-asserted-by":"crossref","first-page":"27294","DOI":"10.1021\/acsnano.5c04655","article-title":"Biomimetic immunoregulators for the multi-target inflammation interruption in autoimmune diseases","volume":"19","author":"Liu","year":"2025","journal-title":"ACS Nano"},{"key":"10.1016\/j.jconrel.2026.115091_bb1305","doi-asserted-by":"crossref","first-page":"834","DOI":"10.1038\/s41565-024-01618-0","article-title":"Photothermal therapy of tuberculosis using targeting pre-activated macrophage membrane-coated nanoparticles","volume":"19","author":"Li","year":"2024","journal-title":"Nat. Nanotechnol."},{"key":"10.1016\/j.jconrel.2026.115091_bb1310","doi-asserted-by":"crossref","first-page":"7394","DOI":"10.1021\/acsnano.2c11762","article-title":"Neutrophil-like biomimic AIE nanoparticles with high-efficiency inflammatory cytokine targeting enable precise photothermal therapy and alleviation of inflammation","volume":"17","author":"Wang","year":"2023","journal-title":"ACS Nano"},{"key":"10.1016\/j.jconrel.2026.115091_bb1315","doi-asserted-by":"crossref","first-page":"1324","DOI":"10.1038\/s41563-022-01360-9","article-title":"Nanoparticle-modified microrobots for in vivo antibiotic delivery to treat acute bacterial pneumonia","volume":"21","author":"Zhang","year":"2022","journal-title":"Nat. Mater."},{"key":"10.1016\/j.jconrel.2026.115091_bb1320","doi-asserted-by":"crossref","first-page":"11","DOI":"10.1016\/j.colsurfb.2019.110755","article-title":"Neutrophil membranes coated, antibiotic agent loaded nanoparticles targeting to the lung inflammation","volume":"188","author":"Wang","year":"2020","journal-title":"Colloid Surf. B-Biointerfaces"},{"key":"10.1016\/j.jconrel.2026.115091_bb1325","doi-asserted-by":"crossref","first-page":"10980","DOI":"10.1073\/pnas.1106634108","article-title":"Erythrocyte membrane-camouflaged polymeric nanoparticles as a biomimetic delivery platform","volume":"108","author":"Hu","year":"2011","journal-title":"Proc. Natl. Acad. Sci. U. S. A."},{"key":"10.1016\/j.jconrel.2026.115091_bb1330","doi-asserted-by":"crossref","first-page":"971","DOI":"10.1126\/science.1229568","article-title":"Minimal \u201cself\u201d peptides that inhibit phagocytic clearance and enhance delivery of nanoparticles","volume":"339","author":"Rodriguez","year":"2013","journal-title":"Science"},{"key":"10.1016\/j.jconrel.2026.115091_bb1335","article-title":"Photoresponsive multirole nanoweapon camouflaged by hybrid cell membrane vesicles for efficient antibacterial therapy of Pseudomonas aeruginosa-infected pneumonia and wound","volume":"11","author":"Liu","year":"2024","journal-title":"Adv. Sci."},{"key":"10.1016\/j.jconrel.2026.115091_bb1340","doi-asserted-by":"crossref","first-page":"445","DOI":"10.1038\/nrmicro1425","article-title":"The interaction of bacterial pathogens with platelets","volume":"4","author":"Fitzgerald","year":"2006","journal-title":"Nat. Rev. Microbiol."},{"key":"10.1016\/j.jconrel.2026.115091_bb1345","doi-asserted-by":"crossref","DOI":"10.1038\/nature15373","article-title":"Nanoparticle biointerfacing by platelet membrane cloaking","volume":"526","author":"Hu","year":"2015","journal-title":"Nature"},{"key":"10.1016\/j.jconrel.2026.115091_bb1350","doi-asserted-by":"crossref","first-page":"2411261","DOI":"10.1002\/advs.202411261","article-title":"Hybrid cell membrane-engineered Nanocarrier for triple-action strategy to address Pseudomonas aeruginosa infection","volume":"12","author":"Zhang","year":"2025","journal-title":"Adv. Sci."},{"key":"10.1016\/j.jconrel.2026.115091_bb1355","doi-asserted-by":"crossref","first-page":"1403","DOI":"10.1021\/nl504798g","article-title":"Modulating antibacterial immunity via bacterial membrane-coated nanoparticles","volume":"15","author":"Gao","year":"2015","journal-title":"Nano Lett."},{"key":"10.1016\/j.jconrel.2026.115091_bb1360","doi-asserted-by":"crossref","DOI":"10.1126\/sciadv.adk9754","article-title":"Biofunctional lipid nanoparticles for precision treatment and prophylaxis of bacterial infections","volume":"10","author":"Peng","year":"2024","journal-title":"Sci. Adv."},{"key":"10.1016\/j.jconrel.2026.115091_bb1365","doi-asserted-by":"crossref","first-page":"69","DOI":"10.1016\/j.addr.2015.04.001","article-title":"Engineered nanoparticles mimicking cell membranes for toxin neutralization","volume":"90","author":"Fang","year":"2015","journal-title":"Adv. Drug Deliv. Rev."},{"key":"10.1016\/j.jconrel.2026.115091_bb1370","doi-asserted-by":"crossref","first-page":"11488","DOI":"10.1073\/pnas.1714267114","article-title":"Macrophage-like nanoparticles concurrently absorbing endotoxins and proinflammatory cytokines for sepsis management","volume":"114","author":"Thamphiwatana","year":"2017","journal-title":"Proc. Natl. Acad. Sci. U. S. A."},{"key":"10.1016\/j.jconrel.2026.115091_bb1375","doi-asserted-by":"crossref","first-page":"39805","DOI":"10.1021\/acsnano.5c12658","article-title":"Natural macrophage membrane-coated nanoparticles as a multifaceted sepsis therapeutic to sequester inflammatory and toxic mediators","volume":"19","author":"Hoffman","year":"2025","journal-title":"ACS Nano"},{"key":"10.1016\/j.jconrel.2026.115091_bb1380","doi-asserted-by":"crossref","DOI":"10.1016\/j.jconrel.2025.113648","article-title":"Inhalable neutrophil-mimicking nanoparticles for chronic obstructive pulmonary disease treatment","volume":"381","author":"Yu","year":"2025","journal-title":"J. Control. Release"},{"key":"10.1016\/j.jconrel.2026.115091_bb1385","doi-asserted-by":"crossref","first-page":"3372","DOI":"10.1021\/acsnano.4c12203","article-title":"Vaccine specifically for immunocompromised individuals against superbugs","volume":"19","author":"Wang","year":"2025","journal-title":"ACS Nano"},{"key":"10.1016\/j.jconrel.2026.115091_bb1390","doi-asserted-by":"crossref","first-page":"7057","DOI":"10.1021\/acs.nanolett.2c01948","article-title":"Biomimetic neutrophil Nanotoxoids elicit potent immunity against Acinetobacter baumannii in multiple models of infection","volume":"22","author":"Zhou","year":"2022","journal-title":"Nano Lett."},{"key":"10.1016\/j.jconrel.2026.115091_bb1395","doi-asserted-by":"crossref","first-page":"336","DOI":"10.1038\/nnano.2013.54","article-title":"A biomimetic nanosponge that absorbs pore-forming toxins","volume":"8","author":"Hu","year":"2013","journal-title":"Nat. Nanotechnol."},{"key":"10.1016\/j.jconrel.2026.115091_bb1400","article-title":"Biomimetic nanosponges suppress in vivo lethality induced by the whole secreted proteins of pathogenic bacteria","volume":"15","author":"Chen","year":"2019","journal-title":"Small"},{"key":"10.1016\/j.jconrel.2026.115091_bb1405","doi-asserted-by":"crossref","first-page":"683","DOI":"10.1089\/scd.2008.0253","article-title":"Pulmonary passage is a major obstacle for intravenous stem cell delivery: the pulmonary first-pass effect","volume":"18","author":"Fischer","year":"2009","journal-title":"Stem Cells Dev."},{"key":"10.1016\/j.jconrel.2026.115091_bb1410","doi-asserted-by":"crossref","first-page":"411","DOI":"10.1007\/s12015-010-9134-5","article-title":"Risks and mechanisms of oncological disease following stem cell transplantation","volume":"6","author":"Anisimov","year":"2010","journal-title":"Stem Cell Rev. Rep."},{"key":"10.1016\/j.jconrel.2026.115091_bb1415","doi-asserted-by":"crossref","DOI":"10.1038\/s41467-020-14344-7","article-title":"Inhalation of lung spheroid cell secretome and exosomes promotes lung repair in pulmonary fibrosis","volume":"11","author":"Dinh","year":"2020","journal-title":"Nat. Commun."},{"key":"10.1016\/j.jconrel.2026.115091_bb1420","article-title":"Clinical applications of stem cell-derived exosomes","volume":"9","author":"Tan","year":"2024","journal-title":"Signal Transduct. Target. Ther."},{"key":"10.1016\/j.jconrel.2026.115091_bb1425","doi-asserted-by":"crossref","first-page":"16362","DOI":"10.1021\/jacs.5c02184","article-title":"Self-adaptive release of stem cell-derived exosomes from a multifunctional hydrogel for accelerating MRSA-infected diabetic wound repair","volume":"147","author":"Wang","year":"2025","journal-title":"J. Am. Chem. Soc."},{"key":"10.1016\/j.jconrel.2026.115091_bb1430","doi-asserted-by":"crossref","DOI":"10.1002\/EXP.20230139","article-title":"Unveiling the promise: exosomes as game-changers in anti-infective therapy","volume":"4","author":"Chavda","year":"2024","journal-title":"Exploration"},{"key":"10.1016\/j.jconrel.2026.115091_bb1435","doi-asserted-by":"crossref","DOI":"10.3402\/jev.v4.27066","article-title":"Biological properties of extracellular vesicles and their physiological functions","volume":"4","author":"Yanez-Mo","year":"2015","journal-title":"J. Extracell. Vesicles"},{"key":"10.1016\/j.jconrel.2026.115091_bb1440","doi-asserted-by":"crossref","DOI":"10.3390\/cells9051111","article-title":"Emerging role of exosomes in diagnosis and treatment of infectious and inflammatory bowel diseases","volume":"9","author":"Larabi","year":"2020","journal-title":"Cells"},{"key":"10.1016\/j.jconrel.2026.115091_bb1445","doi-asserted-by":"crossref","first-page":"7727","DOI":"10.2147\/IJN.S182384","article-title":"Exosome-mediated delivery of functionally active miRNA-142-3p inhibitor reduces tumorigenicity of breast cancer in vitro and in vivo","volume":"13","author":"Naseri","year":"2018","journal-title":"Int. J. 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