{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,30]],"date-time":"2026-10-30T05:33:31Z","timestamp":1793338411603,"version":"4.5.0"},"reference-count":64,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2026,11,1]],"date-time":"2026-11-01T00:00:00Z","timestamp":1793491200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2026,11,1]],"date-time":"2026-11-01T00:00:00Z","timestamp":1793491200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2026,11,1]],"date-time":"2026-11-01T00:00:00Z","timestamp":1793491200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2026,11,1]],"date-time":"2026-11-01T00:00:00Z","timestamp":1793491200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2026,11,1]],"date-time":"2026-11-01T00:00:00Z","timestamp":1793491200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2026,11,1]],"date-time":"2026-11-01T00:00:00Z","timestamp":1793491200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2026,11,1]],"date-time":"2026-11-01T00:00:00Z","timestamp":1793491200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Journal of Controlled Release"],"published-print":{"date-parts":[[2026,11]]},"DOI":"10.1016\/j.jconrel.2026.115266","type":"journal-article","created":{"date-parts":[[2026,8,25]],"date-time":"2026-08-25T23:36:07Z","timestamp":1787700967000},"page":"115266","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":0,"special_numbering":"PA","title":["Targeting the ALDH-RA Axis with RE-Exo@HA hydrogel to achieve scarless endometrial regeneration and fertility restoration in intrauterine adhesions"],"prefix":"10.1016","volume":"399","author":[{"given":"Si","family":"Chen","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shichao","family":"Xing","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wenpeng","family":"Yuan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yue","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jingqi","family":"Liu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jun","family":"Song","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Meiqi","family":"Li","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jingting","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shaoquan","family":"Shi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jianyong","family":"Xu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.jconrel.2026.115266_bb0005","doi-asserted-by":"crossref","first-page":"197","DOI":"10.1146\/annurev-cellbio-011723-021442","article-title":"Mechanisms of regeneration and fibrosis in the endometrium","volume":"39","author":"Ang","year":"2023","journal-title":"Annu. Rev. Cell Dev. Biol."},{"key":"10.1016\/j.jconrel.2026.115266_bb0010","doi-asserted-by":"crossref","first-page":"153","DOI":"10.1093\/humupd\/dmab039","article-title":"Novel microarchitecture of human endometrial glands: implications in endometrial regeneration and pathologies","volume":"28","author":"Tempest","year":"2022","journal-title":"Hum. Reprod. Update"},{"key":"10.1016\/j.jconrel.2026.115266_bb0015","doi-asserted-by":"crossref","first-page":"290","DOI":"10.1038\/s41574-021-00629-4","article-title":"Uterine bleeding: how understanding endometrial physiology underpins menstrual health","volume":"18","author":"Jain","year":"2022","journal-title":"Nat. Rev. Endocrinol."},{"key":"10.1016\/j.jconrel.2026.115266_bb0020","doi-asserted-by":"crossref","first-page":"654","DOI":"10.1038\/nrendo.2016.116","article-title":"Fertile ground: human endometrial programming and lessons in health and disease","volume":"12","author":"Evans","year":"2016","journal-title":"Nat. Rev. Endocrinol."},{"key":"10.1016\/j.jconrel.2026.115266_bb0025","first-page":"423","article-title":"Nanotechnology strategies for endometrium health: are we on the right track?","volume":"54","author":"Herrara","year":"2025","journal-title":"Bioact. Mater."},{"key":"10.1016\/j.jconrel.2026.115266_bb0030","article-title":"Cyclical endometrial repair and regeneration: molecular mechanisms, diseases, and therapeutic interventions","volume":"4","author":"Hu","year":"2023","journal-title":"MedComm (2020)"},{"key":"10.1016\/j.jconrel.2026.115266_bb0035","doi-asserted-by":"crossref","first-page":"555","DOI":"10.1038\/s41586-020-2938-9","article-title":"Fibrosis: from mechanisms to medicines","volume":"587","author":"Henderson","year":"2020","journal-title":"Nature"},{"key":"10.1016\/j.jconrel.2026.115266_bb0040","doi-asserted-by":"crossref","first-page":"705","DOI":"10.1038\/s41584-019-0322-7","article-title":"Shared and distinct mechanisms of fibrosis","volume":"15","author":"Distler","year":"2019","journal-title":"Nat. Rev. Rheumatol."},{"key":"10.1016\/j.jconrel.2026.115266_bb0045","doi-asserted-by":"crossref","first-page":"206","DOI":"10.1038\/s41392-022-01070-3","article-title":"Targeting fibrosis, mechanisms and cilinical trials","volume":"7","author":"Zhao","year":"2022","journal-title":"Signal Transduct. Target. Ther."},{"key":"10.1016\/j.jconrel.2026.115266_bb0050","article-title":"Fibrosis: cross-organ biology and pathways to development of innovative drugs","author":"Rieder","year":"2025","journal-title":"Nat. Rev. Drug Discov."},{"key":"10.1016\/j.jconrel.2026.115266_bb0055","article-title":"Targeting fibrosis: from molecular mechanisms to advanced therapies","volume":"12","author":"Di","year":"2025","journal-title":"Adv. Sci. (Weinh)"},{"key":"10.1016\/j.jconrel.2026.115266_bb0060","doi-asserted-by":"crossref","first-page":"2133","DOI":"10.1016\/S0140-6736(24)00757-8","volume":"403","author":"Diseases, G.B.D., and Injuries, C","year":"2024","journal-title":"Lancet"},{"key":"10.1016\/j.jconrel.2026.115266_bb0065","doi-asserted-by":"crossref","first-page":"665","DOI":"10.1152\/physrev.00067.2017","article-title":"Wound healing: a cellular perspective","volume":"99","author":"Rodrigues","year":"2019","journal-title":"Physiol. Rev."},{"key":"10.1016\/j.jconrel.2026.115266_bb0070","doi-asserted-by":"crossref","first-page":"eadp2974","DOI":"10.1126\/science.adp2974","article-title":"Imperfect wound healing sets the stage for chronic diseases","volume":"386","author":"Martin","year":"2024","journal-title":"Science"},{"key":"10.1016\/j.jconrel.2026.115266_bb0075","doi-asserted-by":"crossref","first-page":"1244","DOI":"10.1016\/j.stem.2024.07.007","article-title":"Hallmarks of regeneration","volume":"31","author":"Poss","year":"2024","journal-title":"Cell Stem Cell"},{"key":"10.1016\/j.jconrel.2026.115266_bb0080","doi-asserted-by":"crossref","first-page":"599","DOI":"10.1038\/s41580-024-00715-1","article-title":"Cellular and molecular mechanisms of skin wound healing","volume":"25","author":"Pena","year":"2024","journal-title":"Nat. Rev. Mol. Cell Biol."},{"key":"10.1016\/j.jconrel.2026.115266_bb0085","doi-asserted-by":"crossref","first-page":"280","DOI":"10.1016\/j.jid.2024.05.027","article-title":"Fetal skin wound healing: key extracellular matrix components and regulators in scarless healing","volume":"145","author":"Gomes","year":"2025","journal-title":"J. Invest. Dermatol."},{"key":"10.1016\/j.jconrel.2026.115266_bb0090","doi-asserted-by":"crossref","first-page":"325","DOI":"10.1016\/j.addr.2018.04.011","article-title":"Scarless wound healing: from development to senescence","volume":"146","author":"Pratsinis","year":"2019","journal-title":"Adv. Drug Deliv. Rev."},{"key":"10.1016\/j.jconrel.2026.115266_bb0095","doi-asserted-by":"crossref","DOI":"10.1002\/SMMD.20220006","article-title":"Developing biomedical engineering technologies for reproductive medicine","volume":"1","author":"Zhu","year":"2022","journal-title":"Smart Med."},{"key":"10.1016\/j.jconrel.2026.115266_bb0100","doi-asserted-by":"crossref","first-page":"35","DOI":"10.1186\/s13287-025-04183-y","article-title":"Enhanced myofibroblast differentiation of eMSCs in intrauterine adhesions","volume":"16","author":"Song","year":"2025","journal-title":"Stem Cell Res. Ther."},{"key":"10.1016\/j.jconrel.2026.115266_bb0105","doi-asserted-by":"crossref","first-page":"543","DOI":"10.1097\/AOG.0000000000005309","article-title":"Etiology, risk factors, and management of Asherman syndrome","volume":"142","author":"Khan","year":"2023","journal-title":"Obstet. Gynecol."},{"key":"10.1016\/j.jconrel.2026.115266_bb0110","doi-asserted-by":"crossref","first-page":"262","DOI":"10.1093\/humupd\/dmt045","article-title":"Systematic review and meta-analysis of intrauterine adhesions after miscarriage: prevalence, risk factors and long-term reproductive outcome","volume":"20","author":"Hooker","year":"2014","journal-title":"Hum. Reprod. Update"},{"key":"10.1016\/j.jconrel.2026.115266_bb0115","doi-asserted-by":"crossref","first-page":"1374","DOI":"10.1093\/humrep\/dey232","article-title":"Asherman\u2019s Syndrome: it may not be all our fault","volume":"33","author":"Santamaria","year":"2018","journal-title":"Hum. Reprod."},{"key":"10.1016\/j.jconrel.2026.115266_bb0120","doi-asserted-by":"crossref","DOI":"10.1016\/j.fertnstert.2024.01.022","article-title":"A retrospective cohort study to examine factors affecting live birth after hysteroscopic treatment of intrauterine adhesions","author":"Zhao","year":"2024","journal-title":"Fertil. Steril."},{"key":"10.1016\/j.jconrel.2026.115266_bb0125","doi-asserted-by":"crossref","DOI":"10.1016\/j.fertnstert.2024.03.016","article-title":"Analysis of factors affecting the prognosis of patients with intrauterine adhesions after transcervical resection of adhesions","author":"Zhang","year":"2024","journal-title":"Fertil. Steril."},{"key":"10.1016\/j.jconrel.2026.115266_bb0130","doi-asserted-by":"crossref","first-page":"1297","DOI":"10.1093\/humrep\/dead092","article-title":"The perinatal outcomes of women treated for Asherman syndrome: a propensity score-matched cohort study","volume":"38","author":"Mara","year":"2023","journal-title":"Hum. Reprod."},{"key":"10.1016\/j.jconrel.2026.115266_bb0135","doi-asserted-by":"crossref","first-page":"70","DOI":"10.1093\/humrep\/deab126.069","article-title":"Reproductive performance of women with and without intrauterine adhesions following recurrent dilatation and curettage for miscarriage: long-term follow-up of a randomized controlled trial","volume":"36","author":"Hooker","year":"2021","journal-title":"Hum. Reprod."},{"key":"10.1016\/j.jconrel.2026.115266_bb0140","doi-asserted-by":"crossref","first-page":"1181","DOI":"10.1016\/j.fertnstert.2021.05.099","article-title":"Live births after Asherman syndrome treatment","volume":"116","author":"Hanstede","year":"2021","journal-title":"Fertil. Steril."},{"key":"10.1016\/j.jconrel.2026.115266_bb0145","doi-asserted-by":"crossref","first-page":"3","DOI":"10.1007\/s00281-024-01030-9","article-title":"Mechanistic insights into intrauterine adhesions","volume":"47","author":"Zhao","year":"2024","journal-title":"Semin. Immunopathol."},{"key":"10.1016\/j.jconrel.2026.115266_bb0150","doi-asserted-by":"crossref","DOI":"10.1093\/humupd\/dmaf019","article-title":"The epidemiology, clinical burden, and prevention of intrauterine adhesions (IUAs) related to surgically induced endometrial trauma: a systematic literature review and selective meta-analyses","author":"Munro","year":"2025","journal-title":"Hum. Reprod. Update"},{"key":"10.1016\/j.jconrel.2026.115266_bb0155","doi-asserted-by":"crossref","first-page":"2264","DOI":"10.1007\/s11427-024-2842-6","article-title":"Development of regenerative therapies targeting fibrotic endometrium in intrauterine adhesion or thin endometrium to restore uterine function","volume":"68","author":"Zhao","year":"2025","journal-title":"Sci. China Life Sci."},{"key":"10.1016\/j.jconrel.2026.115266_bb0160","doi-asserted-by":"crossref","DOI":"10.1002\/smmd.70025","article-title":"Conductive nerve guidance conduits loaded with adipose mesenchymal stem cells for peripheral nerve regeneration","volume":"4","author":"Cheng","year":"2025","journal-title":"Smart Med."},{"key":"10.1016\/j.jconrel.2026.115266_bb0165","doi-asserted-by":"crossref","first-page":"1925","DOI":"10.1038\/s41588-024-01873-w","article-title":"An integrated single-cell reference atlas of the human endometrium","volume":"56","author":"Mareckova","year":"2024","journal-title":"Nat. Genet."},{"key":"10.1016\/j.jconrel.2026.115266_bb0170","doi-asserted-by":"crossref","first-page":"1644","DOI":"10.1038\/s41591-020-1040-z","article-title":"Single-cell transcriptomic atlas of the human endometrium during the menstrual cycle","volume":"26","author":"Wang","year":"2020","journal-title":"Nat. Med."},{"key":"10.1016\/j.jconrel.2026.115266_bb0175","doi-asserted-by":"crossref","first-page":"1698","DOI":"10.1038\/s41588-021-00972-2","article-title":"Mapping the temporal and spatial dynamics of the human endometrium in vivo and in vitro","volume":"53","author":"Garcia-Alonso","year":"2021","journal-title":"Nat. Genet."},{"key":"10.1016\/j.jconrel.2026.115266_bb0180","doi-asserted-by":"crossref","DOI":"10.1016\/j.isci.2023.107201","article-title":"Targeting endometrial inflammation in intrauterine adhesion ameliorates endometrial fibrosis by priming MSCs to secrete C1INH","volume":"26","author":"Yao","year":"2023","journal-title":"iScience"},{"key":"10.1016\/j.jconrel.2026.115266_bb0185","doi-asserted-by":"crossref","first-page":"459","DOI":"10.1186\/s12967-024-05294-5","article-title":"Unveiling heterogeneity in MSCs: exploring marker-based strategies for defining MSC subpopulations","volume":"22","author":"Chen","year":"2024","journal-title":"J. Transl. Med."},{"key":"10.1016\/j.jconrel.2026.115266_bb0190","doi-asserted-by":"crossref","DOI":"10.1073\/pnas.2416089122","article-title":"Retinoic acid antagonizes estrogen signaling to maintain adult uterine cell fate","volume":"122","author":"Yin","year":"2025","journal-title":"Proc. Natl. Acad. Sci. USA"},{"key":"10.1016\/j.jconrel.2026.115266_bb0195","doi-asserted-by":"crossref","first-page":"eadp0176","DOI":"10.1126\/science.adp0176","article-title":"Reactivation of mammalian regeneration by turning on an evolutionarily disabled genetic switch","volume":"388","author":"Lin","year":"2025","journal-title":"Science"},{"key":"10.1016\/j.jconrel.2026.115266_bb0200","doi-asserted-by":"crossref","DOI":"10.1016\/j.pharmthera.2019.107415","article-title":"Modulation of retinoid signaling: therapeutic opportunities in organ fibrosis and repair","volume":"205","author":"Wang","year":"2020","journal-title":"Pharmacol. Ther."},{"key":"10.1016\/j.jconrel.2026.115266_bb0205","doi-asserted-by":"crossref","first-page":"49","DOI":"10.1186\/s13048-015-0179-6","article-title":"Retinoic acid has the potential to suppress endometriosis development","volume":"8","author":"Yamagata","year":"2015","journal-title":"J. Ovarian Res."},{"key":"10.1016\/j.jconrel.2026.115266_bb0210","doi-asserted-by":"crossref","first-page":"84","DOI":"10.1095\/biolreprod.114.119677","article-title":"Retinoic acid biosynthesis is impaired in human and murine endometriosis","volume":"91","author":"Pierzchalski","year":"2014","journal-title":"Biol. Reprod."},{"key":"10.1016\/j.jconrel.2026.115266_bb0215","article-title":"Fibroblast and myofibroblast activation in normal tissue repair and fibrosis","author":"Younesi","year":"2024","journal-title":"Nat. Rev. Mol. Cell Biol."},{"key":"10.1016\/j.jconrel.2026.115266_bb0220","doi-asserted-by":"crossref","first-page":"440","DOI":"10.1016\/j.jconrel.2025.01.013","article-title":"Design, evaluation, and in vitro-in vivo correlation of self-nanoemulsifying drug delivery systems to improve the oral absorption of exenatide","volume":"379","author":"Venkatasubramanian","year":"2025","journal-title":"J. Control. Release"},{"key":"10.1016\/j.jconrel.2026.115266_bb0225","first-page":"449","article-title":"Emerging biomedical technologies for scarless wound healing","volume":"42","author":"Cao","year":"2024","journal-title":"Bioact. Mater."},{"key":"10.1016\/j.jconrel.2026.115266_bb0230","doi-asserted-by":"crossref","first-page":"748","DOI":"10.1093\/humupd\/dmv038","article-title":"Menstrual physiology: implications for endometrial pathology and beyond","volume":"21","author":"Maybin","year":"2015","journal-title":"Hum. Reprod. Update"},{"key":"10.1016\/j.jconrel.2026.115266_bb0235","doi-asserted-by":"crossref","first-page":"1161","DOI":"10.1016\/j.stem.2022.07.006","article-title":"Wound healing, fibroblast heterogeneity, and fibrosis","volume":"29","author":"Talbott","year":"2022","journal-title":"Cell Stem Cell"},{"key":"10.1016\/j.jconrel.2026.115266_bb0240","first-page":"137","article-title":"Endometrial stem\/progenitor cells: the first 10 years","volume":"22","author":"Gargett","year":"2016","journal-title":"Hum. Reprod. Update"},{"key":"10.1016\/j.jconrel.2026.115266_bb0245","doi-asserted-by":"crossref","first-page":"931","DOI":"10.1016\/j.gendis.2022.08.009","article-title":"Endometrial stem\/progenitor cells: properties, origins, and functions","volume":"10","author":"Hong","year":"2023","journal-title":"Genes Dis."},{"key":"10.1016\/j.jconrel.2026.115266_bb0250","doi-asserted-by":"crossref","first-page":"864","DOI":"10.7150\/ijbs.89795","article-title":"Endometrial stem cells: orchestrating dynamic regeneration of endometrium and their implications in diverse endometrial disorders","volume":"20","author":"Hong","year":"2024","journal-title":"Int. J. Biol. Sci."},{"key":"10.1016\/j.jconrel.2026.115266_bb0255","article-title":"Generation of human endometrial assembloids with a luminal epithelium using air-liquid Interface culture methods","volume":"10","author":"Tian","year":"2023","journal-title":"Adv. Sci. (Weinh)"},{"key":"10.1016\/j.jconrel.2026.115266_bb0260","doi-asserted-by":"crossref","first-page":"95","DOI":"10.1038\/s41421-022-00438-7","article-title":"SFRP4(+) stromal cell subpopulation with IGF1 signaling in human endometrial regeneration","volume":"8","author":"Wu","year":"2022","journal-title":"Cell Discov."},{"key":"10.1016\/j.jconrel.2026.115266_bb0265","doi-asserted-by":"crossref","DOI":"10.1126\/sciadv.adi4819","article-title":"Modeling embryo-endometrial interface recapitulating human embryo implantation","volume":"10","author":"Shibata","year":"2024","journal-title":"Sci. Adv."},{"key":"10.1016\/j.jconrel.2026.115266_bb0270","doi-asserted-by":"crossref","DOI":"10.1016\/j.cell.2023.08.020","article-title":"Spatiotemporal insight into early pregnancy governed by immune-featured stromal cells","volume":"186","author":"Yang","year":"2023","journal-title":"Cell"},{"key":"10.1016\/j.jconrel.2026.115266_bb0275","article-title":"Endometrial cells with high ALDH activity contribute to uterine development and regeneration","author":"Tang","year":"2026","journal-title":"Res. Sq."},{"key":"10.1016\/j.jconrel.2026.115266_bb0280","doi-asserted-by":"crossref","first-page":"730","DOI":"10.1016\/j.stemcr.2019.08.015","article-title":"ALDH-dependent glycolytic activation mediates stemness and paclitaxel resistance in patient-derived spheroid models of uterine endometrial cancer","volume":"13","author":"Mori","year":"2019","journal-title":"Stem Cell Rep."},{"key":"10.1016\/j.jconrel.2026.115266_bb0285","doi-asserted-by":"crossref","first-page":"1104","DOI":"10.1038\/s41423-020-0364-4","article-title":"Improved therapeutic consistency and efficacy of mesenchymal stem cells expanded with chemically defined medium for systemic lupus erythematosus","volume":"17","author":"Xu","year":"2020","journal-title":"Cell. Mol. Immunol."},{"key":"10.1016\/j.jconrel.2026.115266_bb0290","doi-asserted-by":"crossref","first-page":"125","DOI":"10.1186\/s13287-020-01641-7","article-title":"Chemical-defined medium supporting the expansion of human mesenchymal stem cells","volume":"11","author":"Xu","year":"2020","journal-title":"Stem Cell Res. Ther."},{"key":"10.1016\/j.jconrel.2026.115266_bb0295","doi-asserted-by":"crossref","first-page":"2","DOI":"10.1186\/s13287-023-03618-8","article-title":"CD317(+) MSCs expanded with chemically defined media have enhanced immunological anti-inflammatory activities","volume":"15","author":"Song","year":"2024","journal-title":"Stem Cell Res. Ther."},{"key":"10.1016\/j.jconrel.2026.115266_bb0300","doi-asserted-by":"crossref","first-page":"92","DOI":"10.1186\/s13287-024-03706-3","article-title":"Improved therapeutic consistency and efficacy of CD317(+) MSCs through stabilizing TSG6 by PTX3","volume":"15","author":"Shi","year":"2024","journal-title":"Stem Cell Res. Ther."},{"key":"10.1016\/j.jconrel.2026.115266_bb0305","doi-asserted-by":"crossref","first-page":"568","DOI":"10.1038\/ncb3516","article-title":"Long-term, hormone-responsive organoid cultures of human endometrium in a chemically defined medium","volume":"19","author":"Turco","year":"2017","journal-title":"Nat. Cell Biol."},{"key":"10.1016\/j.jconrel.2026.115266_bb0310","doi-asserted-by":"crossref","first-page":"1041","DOI":"10.1038\/s41556-019-0360-z","article-title":"Patient-derived organoids from endometrial disease capture clinical heterogeneity and are amenable to drug screening","volume":"21","author":"Boretto","year":"2019","journal-title":"Nat. Cell Biol."},{"key":"10.1016\/j.jconrel.2026.115266_bb0315","first-page":"3935","article-title":"Endometrial membrane organoids from human embryonic stem cell combined with the 3D Matrigel for endometrium regeneration in asherman syndrome","volume":"6","author":"Jiang","year":"2021","journal-title":"Bioact. Mater."},{"key":"10.1016\/j.jconrel.2026.115266_bb0320","doi-asserted-by":"crossref","first-page":"23132","DOI":"10.1073\/pnas.1915389116","article-title":"Self-renewing endometrial epithelial organoids of the human uterus","volume":"116","author":"Fitzgerald","year":"2019","journal-title":"Proc. Natl. Acad. Sci. USA"}],"container-title":["Journal of Controlled Release"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S016836592600670X?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S016836592600670X?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,10,30]],"date-time":"2026-10-30T05:20:29Z","timestamp":1793337629000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S016836592600670X"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,11]]},"references-count":64,"alternative-id":["S016836592600670X"],"URL":"https:\/\/doi.org\/10.1016\/j.jconrel.2026.115266","relation":{},"ISSN":["0168-3659"],"issn-type":[{"value":"0168-3659","type":"print"}],"subject":[],"published":{"date-parts":[[2026,11]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Targeting the ALDH-RA Axis with RE-Exo@HA hydrogel to achieve scarless endometrial regeneration and fertility restoration in intrauterine adhesions","name":"articletitle","label":"Article Title"},{"value":"Journal of Controlled Release","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.jconrel.2026.115266","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2026 Elsevier B.V. All rights are reserved, including those for text and data mining, AI training, and similar technologies.","name":"copyright","label":"Copyright"}],"article-number":"115266"}}