{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,27]],"date-time":"2026-10-27T18:33:46Z","timestamp":1793126026841,"version":"4.5.0"},"reference-count":51,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2026,12,1]],"date-time":"2026-12-01T00:00:00Z","timestamp":1796083200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2026,12,1]],"date-time":"2026-12-01T00:00:00Z","timestamp":1796083200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2026,12,1]],"date-time":"2026-12-01T00:00:00Z","timestamp":1796083200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2026,12,1]],"date-time":"2026-12-01T00:00:00Z","timestamp":1796083200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2026,12,1]],"date-time":"2026-12-01T00:00:00Z","timestamp":1796083200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2026,12,1]],"date-time":"2026-12-01T00:00:00Z","timestamp":1796083200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2026,12,1]],"date-time":"2026-12-01T00:00:00Z","timestamp":1796083200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"funder":[{"DOI":"10.13039\/501100004572","name":"National Health Commission of the People's Republic of China","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100004572","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100010029","name":"Taishan Scholar Foundation of Shandong Province","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100010029","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100012905","name":"Department of Science and Technology of Shandong Province","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100012905","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Journal of Controlled Release"],"published-print":{"date-parts":[[2026,12]]},"DOI":"10.1016\/j.jconrel.2026.115447","type":"journal-article","created":{"date-parts":[[2026,10,16]],"date-time":"2026-10-16T16:05:05Z","timestamp":1792166705000},"page":"115447","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":0,"special_numbering":"PA","title":["Decoding extracellular vesicle\u2013biomolecule interactions: How the biomolecular corona shapes extracellular vesicle biodistribution and clearance in vivo"],"prefix":"10.1016","volume":"400","author":[{"given":"Xiaoyan","family":"Fang","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tianchang","family":"He","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hao","family":"Fan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xiaofei","family":"Li","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Luying","family":"Zhou","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wenhua","family":"Yang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lina","family":"Zhu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yuting","family":"Ge","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wenshuai","family":"Han","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yu","family":"Gao","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Volker","family":"Mail\u00e4nder","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Daniel","family":"Crespy","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Katharina","family":"Landfester","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Junfeng","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shuai","family":"Jiang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.jconrel.2026.115447_bb0005","doi-asserted-by":"crossref","first-page":"152","DOI":"10.1186\/s13045-020-00987-y","article-title":"Isolation and characterization of exosomes for cancer research","volume":"13","author":"Zhu","year":"2020","journal-title":"J. Hematol. Oncol."},{"issue":"11","key":"10.1016\/j.jconrel.2026.115447_bb0010","doi-asserted-by":"crossref","first-page":"17802","DOI":"10.1021\/acsnano.2c08774","article-title":"Exosomesnature's lipid nanoparticles, a rising star in drug delivery and diagnostics","volume":"16","author":"Tenchov","year":"2022","journal-title":"ACS Nano"},{"issue":"5","key":"10.1016\/j.jconrel.2026.115447_bb0015","doi-asserted-by":"crossref","first-page":"1433","DOI":"10.1021\/acssensors.9b00621","article-title":"Ultrasensitive and reversible nanoplatform of urinary exosomes for prostate cancer diagnosis","volume":"4","author":"Li","year":"2019","journal-title":"ACS Sens."},{"key":"10.1016\/j.jconrel.2026.115447_bb0020","doi-asserted-by":"crossref","first-page":"56","DOI":"10.1186\/s12943-022-01509-9","article-title":"Exosomes as a new frontier of cancer liquid biopsy","volume":"21","author":"Yu","year":"2022","journal-title":"Mol. Cancer"},{"key":"10.1016\/j.jconrel.2026.115447_bb0025","doi-asserted-by":"crossref","DOI":"10.1016\/j.pharmthera.2023.108352","article-title":"Extracellular vesicle-based therapeutics: extracellular vesicles as therapeutic targets and agents","volume":"242","author":"Takahashi","year":"2023","journal-title":"Pharmacol. Ther."},{"issue":"1","key":"10.1016\/j.jconrel.2026.115447_bb0030","doi-asserted-by":"crossref","first-page":"145","DOI":"10.1186\/s12964-022-00959-4","article-title":"A review on exosomes application in clinical trials: perspective, questions, and challenges","volume":"20","author":"Rezaie","year":"2022","journal-title":"Cell Commun. Signal"},{"issue":"1","key":"10.1016\/j.jconrel.2026.115447_bb0035","doi-asserted-by":"crossref","first-page":"145","DOI":"10.1186\/s12943-017-0706-8","article-title":"Role of exosomal proteins in cancer diagnosis","volume":"16","author":"Li","year":"2017","journal-title":"Mol. Cancer"},{"issue":"7","key":"10.1016\/j.jconrel.2026.115447_bb0040","doi-asserted-by":"crossref","first-page":"748","DOI":"10.1038\/s41565-021-00931-2","article-title":"Extracellular vesicles as a next-generation drug delivery platform","volume":"16","author":"Herrmann","year":"2021","journal-title":"Nat. Nanotechnol."},{"key":"10.1016\/j.jconrel.2026.115447_bb0045","doi-asserted-by":"crossref","DOI":"10.3389\/fphar.2018.00547","article-title":"Stem cell-derived exosome in cardiovascular diseases: macro roles of micro particles","volume":"9","author":"Yuan","year":"2018","journal-title":"Front. Pharmacol."},{"key":"10.1016\/j.jconrel.2026.115447_bb0050","doi-asserted-by":"crossref","DOI":"10.1016\/j.redox.2023.103016","article-title":"M2 macrophage exosome-derived lncRNA AK083884 protects mice from CVB3-induced viral myocarditis through regulating PKM2\/HIF-1\u03b1 axis mediated metabolic reprogramming of macrophages","volume":"69","author":"Zhang","year":"2024","journal-title":"Redox Biol."},{"issue":"4","key":"10.1016\/j.jconrel.2026.115447_bb0055","doi-asserted-by":"crossref","first-page":"481","DOI":"10.2217\/rme.11.35","article-title":"Mesenchymal stem cell exosome: a novel stem cell-based therapy for cardiovascular disease","volume":"6","author":"Lai","year":"2011","journal-title":"Regen. Med."},{"key":"10.1016\/j.jconrel.2026.115447_bb0060","doi-asserted-by":"crossref","DOI":"10.1016\/j.biomaterials.2022.121949","article-title":"Exosomes based strategies for brain drug delivery","volume":"293","author":"Rehman","year":"2023","journal-title":"Biomaterials"},{"issue":"1","key":"10.1016\/j.jconrel.2026.115447_bb0065","doi-asserted-by":"crossref","DOI":"10.1186\/s12967-022-03493-6","article-title":"Role of exosomes in the pathogenesis, diagnosis, and treatment of central nervous system diseases","volume":"20","author":"Fan","year":"2022","journal-title":"J. Transl. Med."},{"key":"10.1016\/j.jconrel.2026.115447_bb0070","article-title":"Therapeutic potential of mesenchymal stem cell-derived exosomes for allergic airway inflammation","volume":"397\u2013398","author":"Sadeghi","year":"2024","journal-title":"Cell. Immunol."},{"issue":"9","key":"10.1016\/j.jconrel.2026.115447_bb0075","first-page":"2711","article-title":"Enhancement of acellular cartilage matrix scaffold by Wharton's jelly mesenchymal stem cell-derived exosomes to promote osteochondral regeneration","volume":"6","author":"Jiang","year":"2021","journal-title":"Bioact. Mater."},{"key":"10.1016\/j.jconrel.2026.115447_bb0080","article-title":"Protein corona dynamicity contributes to biological destiny disparities of nanoparticles","volume":"28","author":"Zhang","year":"2024","journal-title":"Mater. Today Bio"},{"issue":"4","key":"10.1016\/j.jconrel.2026.115447_bb0085","doi-asserted-by":"crossref","first-page":"1030","DOI":"10.1016\/j.apsb.2020.10.023","article-title":"Impact of particle size and pH on protein corona formation of solid lipid nanoparticles: a proof-of-concept study","volume":"11","author":"Wang","year":"2021","journal-title":"Acta Pharm. Sin. B"},{"key":"10.1016\/j.jconrel.2026.115447_bb0090","doi-asserted-by":"crossref","DOI":"10.1016\/j.addr.2022.114356","article-title":"The effects of protein corona on in vivo fate of nanocarriers","volume":"186","author":"Xiao","year":"2022","journal-title":"Adv. Drug Deliv. Rev."},{"key":"10.1016\/j.jconrel.2026.115447_bb0095","doi-asserted-by":"crossref","first-page":"15","DOI":"10.1016\/j.jconrel.2023.06.014","article-title":"The role of protein corona on nanodrugs for organ-targeting and its prospects of application","volume":"360","author":"Wang","year":"2023","journal-title":"J. Control. Release"},{"issue":"21","key":"10.1016\/j.jconrel.2026.115447_bb0100","doi-asserted-by":"crossref","first-page":"9184","DOI":"10.1021\/jacs.2c02277","article-title":"Chemical and biophysical signatures of the protein Corona in nanomedicine","volume":"144","author":"Ren","year":"2022","journal-title":"J. Am. Chem. Soc."},{"issue":"12","key":"10.1016\/j.jconrel.2026.115447_bb0105","doi-asserted-by":"crossref","DOI":"10.1002\/jev2.12399","article-title":"Uptake of extracellular vesicles into immune cells is enhanced by the protein corona","volume":"12","author":"Dietz","year":"2023","journal-title":"J. Extracell. Vesicles"},{"issue":"11","key":"10.1016\/j.jconrel.2026.115447_bb0110","doi-asserted-by":"crossref","DOI":"10.1002\/jev2.12140","article-title":"Formation of a protein corona on the surface of extracellular vesicles in blood plasma","volume":"10","author":"T\u00f3th","year":"2021","journal-title":"J. Extracell. Vesicles"},{"issue":"4","key":"10.1016\/j.jconrel.2026.115447_bb0115","doi-asserted-by":"crossref","DOI":"10.1002\/jev2.12207","article-title":"A functional corona around extracellular vesicles enhances angiogenesis, skin regeneration and immunomodulation","volume":"11","author":"Wolf","year":"2022","journal-title":"J. Extracell. Vesicles"},{"issue":"2","key":"10.1016\/j.jconrel.2026.115447_bb0120","doi-asserted-by":"crossref","first-page":"170","DOI":"10.20517\/evcna.2023.12","article-title":"Biodistribution of therapeutic extracellular vesicles","volume":"4","author":"Gupta","year":"2023","journal-title":"Extracell. Vesicles Circ. Nucleic Acids"},{"key":"10.1016\/j.jconrel.2026.115447_bb0125","doi-asserted-by":"crossref","DOI":"10.3402\/jev.v4.26238","article-title":"Macrophage-dependent clearance of systemically administered B16BL6-derived exosomes from the blood circulation in mice","volume":"4","author":"Imai","year":"2015","journal-title":"J. Extracell. Vesicles"},{"issue":"1","key":"10.1016\/j.jconrel.2026.115447_bb0130","doi-asserted-by":"crossref","DOI":"10.3402\/jev.v4.26316","article-title":"Extracellular vesicle in vivo biodistribution is determined by cell source, route of administration and targeting","volume":"4","author":"Wiklander","year":"2015","journal-title":"J. Extracell. Vesicles"},{"key":"10.1016\/j.jconrel.2026.115447_bb0135","doi-asserted-by":"crossref","first-page":"3175","DOI":"10.2147\/IJN.S502591","article-title":"Extracellular vesicles: a review of their therapeutic potentials, sources, biodistribution, and administration routes","volume":"20","author":"Su","year":"2025","journal-title":"Int. J. Nanomedicine"},{"issue":"8","key":"10.1016\/j.jconrel.2026.115447_bb0140","doi-asserted-by":"crossref","DOI":"10.1002\/jev2.12085","article-title":"Biodistribution of extracellular vesicles following administration into animals: a systematic review","volume":"10","author":"Kang","year":"2021","journal-title":"J. Extracell. Vesicles"},{"issue":"2","key":"10.1016\/j.jconrel.2026.115447_bb0145","doi-asserted-by":"crossref","DOI":"10.1002\/jev2.12404","article-title":"Minimal information for studies of extracellular vesicles (MISEV2023): from basic to advanced approaches","volume":"13","author":"Welsh","year":"2024","journal-title":"J. Extracell. Vesicles"},{"issue":"1","key":"10.1016\/j.jconrel.2026.115447_bb0150","doi-asserted-by":"crossref","DOI":"10.1038\/s41598-021-83241-w","article-title":"Selective loss of microvesicles is a major issue of the differential centrifugation isolation protocols","volume":"11","author":"Nigro","year":"2021","journal-title":"Sci. Rep."},{"issue":"6","key":"10.1016\/j.jconrel.2026.115447_bb0155","doi-asserted-by":"crossref","first-page":"846","DOI":"10.1038\/s41565-023-01585-y","article-title":"Cellular uptake and in vivo distribution of mesenchymal-stem-cell-derived extracellular vesicles are protein corona dependent","volume":"19","author":"Liam-Or","year":"2024","journal-title":"Nat. Nanotechnol."},{"key":"10.1016\/j.jconrel.2026.115447_bb0160","doi-asserted-by":"crossref","first-page":"161","DOI":"10.1007\/978-1-4939-7163-3_16","article-title":"Isolation of Kupffer cells and hepatocytes from a single mouse liver","volume":"1639","author":"Aparicio-Vergara","year":"2017","journal-title":"Methods Mol. Biol."},{"issue":"1","key":"10.1016\/j.jconrel.2026.115447_bb0165","doi-asserted-by":"crossref","first-page":"16","DOI":"10.1186\/s12951-018-0437-z","article-title":"Exosome origin determines cell targeting and the transfer of therapeutic nanoparticles towards target cells","volume":"17","author":"Sancho-Albero","year":"2019","journal-title":"J. Nanobiotechnol."},{"issue":"1","key":"10.1016\/j.jconrel.2026.115447_bb0170","article-title":"Cell membrane coating integrity affects the internalization mechanism of biomimetic nanoparticles","volume":"12","author":"Liu","year":"2021","journal-title":"Nat. Commun."},{"key":"10.1016\/j.jconrel.2026.115447_bb0175","doi-asserted-by":"crossref","first-page":"170","DOI":"10.1016\/j.jconrel.2024.02.015","article-title":"Engineered exosomes with enhanced stability and delivery efficiency for glioblastoma therapy","volume":"368","author":"Wang","year":"2024","journal-title":"J. Control. Release"},{"issue":"30","key":"10.1016\/j.jconrel.2026.115447_bb0180","doi-asserted-by":"crossref","first-page":"9202","DOI":"10.1021\/acs.nanolett.4c01469","article-title":"In situ measurement of nanoparticle\u2013blood protein adsorption and its heterogeneity with single-nanoparticle resolution via dual fluorescence quantification","volume":"24","author":"Niu","year":"2024","journal-title":"Nano Lett."},{"key":"10.1016\/j.jconrel.2026.115447_bb0185","doi-asserted-by":"crossref","first-page":"61","DOI":"10.1016\/j.jare.2021.01.001","article-title":"Camouflage strategies for therapeutic exosomes evasion from phagocytosis","volume":"31","author":"Parada","year":"2021","journal-title":"J. Adv. Res."},{"issue":"23","key":"10.1016\/j.jconrel.2026.115447_bb0190","doi-asserted-by":"crossref","first-page":"3341","DOI":"10.1002\/smll.201101076","article-title":"Quantitative assessment of the comparative nanoparticle-uptake efficiency of a range of cell lines","volume":"7","author":"dos Santos","year":"2011","journal-title":"Small"},{"issue":"3","key":"10.1016\/j.jconrel.2026.115447_bb0195","doi-asserted-by":"crossref","first-page":"561","DOI":"10.1038\/mt.2009.281","article-title":"The use of inhibitors to study endocytic pathways of gene carriers: optimization and pitfalls","volume":"18","author":"Vercauteren","year":"2010","journal-title":"Mol. Ther."},{"issue":"12","key":"10.1016\/j.jconrel.2026.115447_bb0200","doi-asserted-by":"crossref","first-page":"1135","DOI":"10.1002\/mabi.200800123","article-title":"Uptake mechanism of oppositely charged fluorescent nanoparticles in HeLa cells","volume":"8","author":"Dausend","year":"2008","journal-title":"Macromol. Biosci."},{"issue":"6","key":"10.1016\/j.jconrel.2026.115447_bb0205","doi-asserted-by":"crossref","first-page":"839","DOI":"10.1016\/j.devcel.2006.04.002","article-title":"Dynasore, a cell-permeable inhibitor of dynamin","volume":"10","author":"Macia","year":"2006","journal-title":"Dev. Cell"},{"issue":"10","key":"10.1016\/j.jconrel.2026.115447_bb0210","doi-asserted-by":"crossref","first-page":"11107","DOI":"10.1021\/acsnano.9b03824","article-title":"Corona composition can affect the mechanisms cells use to internalize nanoparticles","volume":"13","author":"Francia","year":"2019","journal-title":"ACS Nano"},{"issue":"1","key":"10.1016\/j.jconrel.2026.115447_bb0215","doi-asserted-by":"crossref","DOI":"10.1038\/s41467-020-20886-7","article-title":"Surface chemistry-mediated modulation of adsorbed albumin folding state specifies nanocarrier clearance by distinct macrophage subsets","volume":"12","author":"Vincent","year":"2021","journal-title":"Nat. Commun."},{"issue":"1","key":"10.1016\/j.jconrel.2026.115447_bb0220","doi-asserted-by":"crossref","DOI":"10.3402\/jev.v3.24641","article-title":"Routes and mechanisms of extracellular vesicle uptake","volume":"3","author":"Mulcahy","year":"2014","journal-title":"J. Extracell. Vesicles"},{"key":"10.1016\/j.jconrel.2026.115447_bb0225","doi-asserted-by":"crossref","first-page":"892","DOI":"10.3389\/fimmu.2018.00892","article-title":"Exploring the immunomodulatory moonlighting activities of acute phase proteins for tolerogenic dendritic cell generation","volume":"9","author":"Serrano","year":"2018","journal-title":"Front. Immunol."},{"key":"10.1016\/j.jconrel.2026.115447_bb0230","doi-asserted-by":"crossref","first-page":"20","DOI":"10.1016\/j.biomaterials.2015.11.028","article-title":"Soluble and immobilized graphene oxide activates complement system differently dependent on surface oxidation state","volume":"78","author":"Wibroe","year":"2016","journal-title":"Biomaterials"},{"key":"10.1016\/j.jconrel.2026.115447_bb0235","doi-asserted-by":"crossref","first-page":"83","DOI":"10.1016\/j.addr.2020.04.012","article-title":"Complement activation by drug carriers and particulate pharmaceuticals: principles, challenges and opportunities","volume":"157","author":"Moghimi","year":"2020","journal-title":"Adv. Drug Deliv. Rev."},{"key":"10.1016\/j.jconrel.2026.115447_bb0240","doi-asserted-by":"crossref","first-page":"402","DOI":"10.3389\/fimmu.2014.00402","article-title":"Complement, c1q, and c1q-related molecules regulate macrophage polarization","volume":"5","author":"Bohlson","year":"2014","journal-title":"Front. Immunol."},{"key":"10.1016\/j.jconrel.2026.115447_bb0245","doi-asserted-by":"crossref","DOI":"10.3389\/fimmu.2022.918551","article-title":"Complement membrane attack complex is an immunometabolic regulator of NLRP3 activation and IL-18 secretion in human macrophages","volume":"13","author":"Jimenez-Duran","year":"2022","journal-title":"Front. Immunol."},{"issue":"3","key":"10.1016\/j.jconrel.2026.115447_bb0250","doi-asserted-by":"crossref","first-page":"260","DOI":"10.1038\/s41565-018-0344-3","article-title":"Immunoglobulin deposition on biomolecule corona determines complement opsonization efficiency of preclinical and clinical nanoparticles","volume":"14","author":"Vu","year":"2019","journal-title":"Nat. Nanotechnol."},{"issue":"7","key":"10.1016\/j.jconrel.2026.115447_bb0255","doi-asserted-by":"crossref","DOI":"10.1002\/jev2.12248","article-title":"Extracellular vesicles engineered to bind albumin demonstrate extended circulation time and lymph node accumulation in mouse models","volume":"11","author":"Liang","year":"2022","journal-title":"J. Extracell. Vesicles"}],"container-title":["Journal of Controlled Release"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0168365926008515?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0168365926008515?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,10,27]],"date-time":"2026-10-27T17:50:57Z","timestamp":1793123457000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0168365926008515"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,12]]},"references-count":51,"alternative-id":["S0168365926008515"],"URL":"https:\/\/doi.org\/10.1016\/j.jconrel.2026.115447","relation":{},"ISSN":["0168-3659"],"issn-type":[{"value":"0168-3659","type":"print"}],"subject":[],"published":{"date-parts":[[2026,12]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Decoding extracellular vesicle\u2013biomolecule interactions: How the biomolecular corona shapes extracellular vesicle biodistribution and clearance in vivo","name":"articletitle","label":"Article Title"},{"value":"Journal of Controlled Release","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.jconrel.2026.115447","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2026 Elsevier B.V. All rights are reserved, including those for text and data mining, AI training, and similar technologies.","name":"copyright","label":"Copyright"}],"article-number":"115447"}}