{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,28]],"date-time":"2026-02-28T23:15:22Z","timestamp":1772320522417,"version":"3.50.1"},"reference-count":47,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2023,11,1]],"date-time":"2023-11-01T00:00:00Z","timestamp":1698796800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2023,11,1]],"date-time":"2023-11-01T00:00:00Z","timestamp":1698796800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","journal-cot.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Journal of Clinical Orthopaedics and Trauma"],"published-print":{"date-parts":[[2023,11]]},"DOI":"10.1016\/j.jcot.2023.102278","type":"journal-article","created":{"date-parts":[[2023,11,9]],"date-time":"2023-11-09T03:42:29Z","timestamp":1699501349000},"page":"102278","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":6,"special_numbering":"C","title":["Association between vitamin D and knee osteoarthritis in Indian population: A systematic review and meta-analysis"],"prefix":"10.1016","volume":"46","author":[{"ORCID":"https:\/\/orcid.org\/0009-0007-9151-5964","authenticated-orcid":false,"given":"R.","family":"Annamalai","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7335-4593","authenticated-orcid":false,"given":"A.","family":"Sujhithra","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1794-3166","authenticated-orcid":false,"given":"D.","family":"Danis Vijay","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.jcot.2023.102278_bib1","unstructured":"Mahajan R., Mahajan A., Khan S. Study of levels of 25 hydroxycholecalciferol (25(OH)D3) in patients of knee osteoarthritis in a tertiary care hospital in northern India. Indian J Appl Res. 2019 July; 9 (7)\u202f: 71-72."},{"issue":"2","key":"10.1016\/j.jcot.2023.102278_bib2","doi-asserted-by":"crossref","first-page":"151","DOI":"10.1007\/s11914-012-0098-z","article-title":"Vitamin D and bone","volume":"10","author":"Bikle","year":"2012","journal-title":"Curr Osteoporos Rep"},{"key":"10.1016\/j.jcot.2023.102278_bib3","doi-asserted-by":"crossref","first-page":"693","DOI":"10.3390\/nu2070693","article-title":"Vitamin D and bone health; potential mechanisms","volume":"2","author":"Laird","year":"2010","journal-title":"Nutrients"},{"issue":"6","key":"10.1016\/j.jcot.2023.102278_bib4","doi-asserted-by":"crossref","first-page":"1678S","DOI":"10.1093\/ajcn\/80.6.1678S","article-title":"Sunlight and vitamin D for bone health and prevention of autoimmune diseases, cancers, and cardiovascular disease","volume":"80","author":"Holick","year":"2004","journal-title":"Am J Clin Nutr"},{"key":"10.1016\/j.jcot.2023.102278_bib5","first-page":"2015","article-title":"Role of vitamin D in osteoarthritis: molecular, cellular, and clinical perspectives","author":"Mabey","year":"2015","journal-title":"Int J Endocrinol"},{"issue":"11","key":"10.1016\/j.jcot.2023.102278_bib6","doi-asserted-by":"crossref","first-page":"4035","DOI":"10.3390\/nu13114035","article-title":"The role of vitamin D in early knee osteoarthritis and its relationship with their physical and psychological status","volume":"13","author":"Alabajos-Cea","year":"2021","journal-title":"Nutrients"},{"issue":"4","key":"10.1016\/j.jcot.2023.102278_bib7","doi-asserted-by":"crossref","DOI":"10.1136\/bmjopen-2019-035302","article-title":"Effect of vitamin D supplementation on pain and physical function in patients with knee osteoarthritis (OA): an OA Trial Bank protocol for a systematic review and individual patient data (IPD) meta-analysis","volume":"10","author":"Jin","year":"2020","journal-title":"BMJ Open"},{"issue":"4","key":"10.1016\/j.jcot.2023.102278_bib8","first-page":"934","article-title":"A comparative study of serum vitamin d levels in patients with knee osteoarthritis and age matched healthy population","volume":"3","author":"Khan","year":"2017","journal-title":"Int J Orthopaed"},{"issue":"6","key":"10.1016\/j.jcot.2023.102278_bib9","doi-asserted-by":"crossref","first-page":"1161","DOI":"10.18203\/issn.2455-4510.IntJResOrthop20203961","article-title":"VA study on correlation between deficiency of vitamin D and knee osteoathritis among patients attending a tertiary care hospital in Andhra Pradesh","volume":"6","author":"Rao","year":"2020","journal-title":"Int J Res Orthop"},{"issue":"10","key":"10.1016\/j.jcot.2023.102278_bib10","doi-asserted-by":"crossref","first-page":"418","DOI":"10.5312\/wjo.v11.i10.418","article-title":"Association of vitamin D and knee osteoarthritis in younger individuals","volume":"11","author":"Tripathy","year":"2020","journal-title":"World J Orthoped"},{"key":"10.1016\/j.jcot.2023.102278_bib11","doi-asserted-by":"crossref","first-page":"1627","DOI":"10.1007\/s00264-010-1186-2","article-title":"Association between serum vitamin D deficiency and knee osteoarthritis","volume":"35","author":"Heidari","year":"2011","journal-title":"Int Orthop"},{"issue":"1","key":"10.1016\/j.jcot.2023.102278_bib12","doi-asserted-by":"crossref","first-page":"15","DOI":"10.1080\/07315724.2013.875439","article-title":"Elucidation of dietary risk factors in osteoarthritis knee\u2014a case-control study","volume":"34","author":"Sanghi","year":"2015","journal-title":"J Am Coll Nutr"},{"issue":"4","key":"10.1016\/j.jcot.2023.102278_bib13","doi-asserted-by":"crossref","first-page":"199","DOI":"10.1016\/j.jcot.2014.09.002","article-title":"A study of the prevalence of osteoporosis and hypovitaminosis D in patients with primary knee osteoarthritis","volume":"5","author":"Ghosh","year":"2014","journal-title":"J Clin Orthopaed Trauma"},{"issue":"1","key":"10.1016\/j.jcot.2023.102278_bib14","first-page":"1","article-title":"Vitamin D deficiency showed association with knee osteoarthritis in Tamilnadu population\u2013A pilot study","volume":"4","author":"Annamalai","year":"2018","journal-title":"Indian J Orthop Surg"},{"issue":"3","key":"10.1016\/j.jcot.2023.102278_bib15","doi-asserted-by":"crossref","first-page":"491","DOI":"10.4103\/ijmr.IJMR_873_19","article-title":"Serum levels of osteoprotegerin, RANK-L & vitamin D in different stages of osteoarthritis of the knee","volume":"154","author":"Naik","year":"2021","journal-title":"Indian J Med Res"},{"issue":"4","key":"10.1016\/j.jcot.2023.102278_bib16","doi-asserted-by":"crossref","first-page":"1272","DOI":"10.3390\/nu13041272","article-title":"Association of gut microbiome and vitamin d deficiency in knee osteoarthritis patients: a pilot study","volume":"13","author":"Ramasamy","year":"2021","journal-title":"Nutrients"},{"issue":"2","key":"10.1016\/j.jcot.2023.102278_bib17","doi-asserted-by":"crossref","first-page":"283","DOI":"10.53350\/pjmhs22162283","article-title":"Association between vitamin-D deficiency and knee osteoarthritis","volume":"16","author":"Afzal","year":"2022","journal-title":"Pak J Med Health Sci"},{"key":"10.1016\/j.jcot.2023.102278_bib18","unstructured":"Rajak RK, Golwara BK. A Case Control Study to Establish the Association between Vitamin D Deficiency with Knee Osteoarthritis."},{"issue":"10","key":"10.1016\/j.jcot.2023.102278_bib19","doi-asserted-by":"crossref","DOI":"10.18103\/mra.v10i10.3284","article-title":"Vitamin D deficiency is associated with knee osteoarthritis and is implicated in the osteoarthritis severity","volume":"10","author":"Mathkhor","year":"2022","journal-title":"Med Res Arch"},{"issue":"4","key":"10.1016\/j.jcot.2023.102278_bib20","doi-asserted-by":"crossref","first-page":"216","DOI":"10.31138\/mjr.30.4.216","article-title":"Association between serum vitamin D deficiency and knee osteoarthritis","volume":"30","author":"Anari","year":"2019","journal-title":"Mediterr J Rheumatol"},{"issue":"4","key":"10.1016\/j.jcot.2023.102278_bib21","doi-asserted-by":"crossref","first-page":"350","DOI":"10.31138\/mjr.32.4.350","article-title":"Vitamin K and D status in patients with knee osteoarthritis: an analytical cross-sectional study","volume":"32","author":"Askari","year":"2021","journal-title":"Mediterr J Rheumatol"},{"key":"10.1016\/j.jcot.2023.102278_bib22","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1186\/s12889-021-11888-1","article-title":"High prevalence of vitamin D deficiency among the South Asian adults: a systematic review and meta-analysis","volume":"21","author":"Siddiqee","year":"2021","journal-title":"BMC Publ Health"},{"issue":"1","key":"10.1016\/j.jcot.2023.102278_bib23","doi-asserted-by":"crossref","first-page":"34","DOI":"10.3329\/bjmed.v28i1.31900","article-title":"Hypovitaminosis D in adult-A systemic review","volume":"28","author":"Islam","year":"2017","journal-title":"Bangladesh J Med"},{"issue":"3","key":"10.1016\/j.jcot.2023.102278_bib24","first-page":"118","article-title":"Meta Analysis Vitamin D deficiency status in Turkey: a meta-analysis","volume":"2","author":"Alpdemir","year":"2019","journal-title":"Int J Med Biochem"},{"key":"10.1016\/j.jcot.2023.102278_bib25","first-page":"1","article-title":"High prevalence of vitamin D deficiency in Asia: a systematic review and meta-analysis","author":"Jiang","year":"2021","journal-title":"Crit Rev Food Sci Nutr"},{"issue":"5","key":"10.1016\/j.jcot.2023.102278_bib26","doi-asserted-by":"crossref","first-page":"1484","DOI":"10.1210\/clinem\/dgab892","article-title":"Prognostic and therapeutic role of vitamin D in COVID-19: systematic review and meta-analysis","volume":"107","author":"Dissanayake","year":"2022","journal-title":"J Clin Endocrinol Metabol"},{"issue":"6","key":"10.1016\/j.jcot.2023.102278_bib27","doi-asserted-by":"crossref","first-page":"907","DOI":"10.1080\/14787210.2022.2035217","article-title":"COVID-19 and vitamin D (Co-VIVID study): a systematic review and meta-analysis of randomized controlled trials","volume":"20","author":"Varikasuvu","year":"2022","journal-title":"Expert Rev Anti-infect Ther"},{"issue":"5","key":"10.1016\/j.jcot.2023.102278_bib28","doi-asserted-by":"crossref","first-page":"1636","DOI":"10.1093\/advances\/nmab012","article-title":"Association of vitamin D status with SARS-CoV-2 infection or COVID-19 severity: a systematic review and meta-analysis","volume":"12","author":"Kazemi","year":"2021","journal-title":"Adv Nutr"},{"key":"10.1016\/j.jcot.2023.102278_bib29","first-page":"84","article-title":"Effects of vitamin D serum level on morbidity and mortality in patients with COVID-19: a systematic review and meta-analysis","volume":"25","author":"Hu","year":"2022","journal-title":"J Pharm Pharmaceut Sci"},{"issue":"35","key":"10.1016\/j.jcot.2023.102278_bib30","doi-asserted-by":"crossref","DOI":"10.1097\/MD.0000000000012179","article-title":"The association between vitamin D status and tuberculosis in children: a meta-analysis","volume":"97","author":"Gou","year":"2018","journal-title":"Medicine"},{"key":"10.1016\/j.jcot.2023.102278_bib31","doi-asserted-by":"crossref","first-page":"91","DOI":"10.2147\/DDDT.S79870","article-title":"Vitamin D deficiency and the risk of tuberculosis: a meta-analysis","author":"Huang","year":"2016","journal-title":"Drug Des Dev Ther"},{"issue":"9","key":"10.1016\/j.jcot.2023.102278_bib32","first-page":"13","article-title":"Association of vitamin D deficiency with pulmonary tuberculosis: a systematic review and meta-analysis","author":"Kafle","year":"2021","journal-title":"Cureus"},{"issue":"3","key":"10.1016\/j.jcot.2023.102278_bib33","doi-asserted-by":"crossref","first-page":"307","DOI":"10.3390\/nu9030307","article-title":"The association between vitamin D deficiency and diabetic retinopathy in type 2 diabetes: a meta-analysis of observational studies","volume":"9","author":"Luo","year":"2017","journal-title":"Nutrients"},{"issue":"10","key":"10.1016\/j.jcot.2023.102278_bib34","doi-asserted-by":"crossref","first-page":"8366","DOI":"10.3390\/nu7105398","article-title":"Vitamin D deficiency increases the risk of gestational diabetes mellitus: a meta-analysis of observational studies","volume":"7","author":"Zhang","year":"2015","journal-title":"Nutrients"},{"issue":"1","key":"10.1016\/j.jcot.2023.102278_bib35","doi-asserted-by":"crossref","first-page":"8","DOI":"10.1038\/s41387-019-0078-9","article-title":"Vitamin D and diabetic foot ulcer: a systematic review and meta-analysis","volume":"9","author":"Dai","year":"2019","journal-title":"Nutr Diabetes"},{"issue":"3","key":"10.1016\/j.jcot.2023.102278_bib36","first-page":"95","article-title":"A meta-analysis on vitamin D deficiency in patients with sickle cell disease","volume":"2","author":"Mohamed","year":"2020","journal-title":"Med J"},{"issue":"1","key":"10.1016\/j.jcot.2023.102278_bib37","article-title":"Defining vitamin D deficiency in patients with sickle cell disease; A meta-analysis","volume":"10","author":"Sahu","year":"2022","journal-title":"J Parathyroid Dis"},{"key":"10.1016\/j.jcot.2023.102278_bib38","doi-asserted-by":"crossref","first-page":"691","DOI":"10.1590\/1806-9282.65.5.691","article-title":"Prevalence of hypovitaminosis D in postmenopausal women: a systematic review","volume":"65","author":"Valladares","year":"2019","journal-title":"Rev Assoc M\u00e9d Bras"},{"issue":"11","key":"10.1016\/j.jcot.2023.102278_bib39","first-page":"26","article-title":"Osteoporosis in postmenopausal females with primary knee osteoarthritis in a vitamin D deficient population","volume":"65","author":"Dhaon","year":"2017","journal-title":"J Assoc Phys India"},{"issue":"3","key":"10.1016\/j.jcot.2023.102278_bib40","first-page":"893","article-title":"Primary osteoarthritis of the knee joint and osteoporosis in postmenopausal females in a tertiary care hospital","volume":"7","author":"Borkar","year":"2021","journal-title":"Int J Orthopaed"},{"issue":"10","key":"10.1016\/j.jcot.2023.102278_bib41","doi-asserted-by":"crossref","first-page":"1395","DOI":"10.3390\/nu10101395","article-title":"The association between vitamin D deficiency and sleep disorders: a systematic review and meta-analysis","volume":"10","author":"Gao","year":"2018","journal-title":"Nutrients"},{"issue":"10","key":"10.1016\/j.jcot.2023.102278_bib42","doi-asserted-by":"crossref","first-page":"5696","DOI":"10.1002\/fsn3.1867","article-title":"A meta\u2010analysis: does vitamin D play a promising role in sleep disorders?","volume":"8","author":"Yan","year":"2020","journal-title":"Food Sci Nutr"},{"issue":"1","key":"10.1016\/j.jcot.2023.102278_bib43","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1186\/s12931-020-01554-2","article-title":"The association between serum vitamin D and obstructive sleep apnea: an updated meta-analysis","volume":"21","author":"Li","year":"2020","journal-title":"Respir Res"},{"issue":"3","key":"10.1016\/j.jcot.2023.102278_bib44","doi-asserted-by":"crossref","first-page":"1430","DOI":"10.3390\/ijms23031430","article-title":"The role of vitamin D in sleep disorders of children and adolescents: a systematic review","volume":"23","author":"Prono","year":"2022","journal-title":"Int J Mol Sci"},{"issue":"3","key":"10.1016\/j.jcot.2023.102278_bib45","doi-asserted-by":"crossref","first-page":"227","DOI":"10.1080\/07315724.2018.1494641","article-title":"Use of vitamin D supplements in osteoarthritis: an observational study in a tertiary health care facility","volume":"38","author":"Thomas","year":"2019","journal-title":"J Am Coll Nutr"},{"key":"10.1016\/j.jcot.2023.102278_bib46","doi-asserted-by":"crossref","first-page":"14","DOI":"10.1016\/j.ijsu.2017.08.010","article-title":"The effect of vitamin D supplementation on knee osteoarthritis: a meta-analysis of randomized controlled trials","volume":"46","author":"Gao","year":"2017","journal-title":"Int J Surg"},{"issue":"7","key":"10.1016\/j.jcot.2023.102278_bib47","doi-asserted-by":"crossref","first-page":"488","DOI":"10.1016\/j.jash.2018.04.009","article-title":"Effect of vitamin D supplementation on blood pressure parameters in patients with vitamin D deficiency: a systematic review and meta-analysis","volume":"12","author":"Shu","year":"2018","journal-title":"J Am Soc Hypertens"}],"container-title":["Journal of Clinical Orthopaedics and Trauma"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0976566223001868?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0976566223001868?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,19]],"date-time":"2025-10-19T08:02:59Z","timestamp":1760860979000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0976566223001868"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,11]]},"references-count":47,"alternative-id":["S0976566223001868"],"URL":"https:\/\/doi.org\/10.1016\/j.jcot.2023.102278","relation":{},"ISSN":["0976-5662"],"issn-type":[{"value":"0976-5662","type":"print"}],"subject":[],"published":{"date-parts":[[2023,11]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Association between vitamin D and knee osteoarthritis in Indian population: A systematic review and meta-analysis","name":"articletitle","label":"Article Title"},{"value":"Journal of Clinical Orthopaedics and Trauma","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.jcot.2023.102278","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2023 Delhi Orthopedic Association. All rights reserved.","name":"copyright","label":"Copyright"}],"article-number":"102278"}}