{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,20]],"date-time":"2026-07-20T21:41:13Z","timestamp":1784583673145,"version":"3.55.0"},"reference-count":18,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2025,11,1]],"date-time":"2025-11-01T00:00:00Z","timestamp":1761955200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2025,11,1]],"date-time":"2025-11-01T00:00:00Z","timestamp":1761955200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","journal-cot.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Journal of Clinical Orthopaedics and Trauma"],"published-print":{"date-parts":[[2025,11]]},"DOI":"10.1016\/j.jcot.2025.103182","type":"journal-article","created":{"date-parts":[[2025,8,26]],"date-time":"2025-08-26T23:25:49Z","timestamp":1756250749000},"page":"103182","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":6,"special_numbering":"C","title":["Bisphosphonate therapy in pediatric fibrous dysplasia: A systematic review of clinical, biochemical, and radiological outcomes"],"prefix":"10.1016","volume":"70","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-9182-4851","authenticated-orcid":false,"given":"Anil","family":"Regmi","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3482-4705","authenticated-orcid":false,"given":"Bishwa Bandhu","family":"Niraula","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"issue":"2","key":"10.1016\/j.jcot.2025.103182_bib1","doi-asserted-by":"crossref","first-page":"84","DOI":"10.55275\/JPOSNA-2020-84","article-title":"Fibrous dysplasia: recent developments and modern management alternatives","volume":"2","author":"Baghdadi","year":"2020","journal-title":"J Pediatr Orthop Soc North Am"},{"issue":"1","key":"10.1016\/j.jcot.2025.103182_bib2","doi-asserted-by":"crossref","first-page":"55","DOI":"10.1016\/j.berh.2007.11.004","article-title":"Fibrous dysplasia of bone and McCune\u2013Albright syndrome","volume":"22","author":"Chapurlat","year":"2008","journal-title":"Best Pract Res Clin Rheumatol"},{"key":"10.1016\/j.jcot.2025.103182_bib3","doi-asserted-by":"crossref","DOI":"10.3389\/fped.2024.1502262","article-title":"A narrative review of the literature on the pediatric orthopedic management of fibrous dysplasia","volume":"12","author":"Paris","year":"2025","journal-title":"Front Pediatr"},{"issue":"1","key":"10.1016\/j.jcot.2025.103182_bib4","doi-asserted-by":"crossref","first-page":"60","DOI":"10.1097\/MED.0000000000000847","article-title":"Fibrous dysplasia in children and its management","volume":"31","author":"Gun","year":"2024","journal-title":"Curr Opin Endocrinol Diabetes Obes"},{"key":"10.1016\/j.jcot.2025.103182_bib5","article-title":"Update on the medical management of fibrous dysplasia of the bone","volume":"16","author":"Wentworth","year":"2025","journal-title":"Therapeutic Adv Endocrinol"},{"issue":"5","key":"10.1016\/j.jcot.2025.103182_bib6","doi-asserted-by":"crossref","first-page":"1371","DOI":"10.1210\/clinem\/dgad657","article-title":"Management of RANKL-mediated disorders with denosumab in children and adolescents: a global expert guidance document","volume":"109","author":"Vanderniet","year":"2024","journal-title":"J Clin Endocrinol Metab"},{"key":"10.1016\/j.jcot.2025.103182_bib7","doi-asserted-by":"crossref","DOI":"10.3389\/fendo.2023.1266986","article-title":"A practical guide to the diagnosis and management of osteoporosis in childhood and adolescence","volume":"14","author":"Ward","year":"2024","journal-title":"Front Endocrinol"},{"issue":"Supplement","key":"10.1016\/j.jcot.2025.103182_bib8","doi-asserted-by":"crossref","first-page":"583","DOI":"10.1515\/JPEM.2006.19.S2.583","article-title":"Bisphosphonate treatment of bone fibrous dysplasia in McCuneAlbright syndrome","volume":"19","author":"Lala","year":"2006","journal-title":"J Pediatr Endocrinol Metabol"},{"issue":"4","key":"10.1016\/j.jcot.2025.103182_bib9","doi-asserted-by":"crossref","first-page":"384","DOI":"10.1007\/s00223-013-9829-0","article-title":"Clinical and radiological observations in a case series of 26 patients with fibrous dysplasia","volume":"94","author":"Thomsen","year":"2014","journal-title":"Calcif Tissue Int"},{"issue":"10","key":"10.1016\/j.jcot.2025.103182_bib10","doi-asserted-by":"crossref","first-page":"4569","DOI":"10.1210\/jc.2003-030050","article-title":"Effect of pamidronate treatment in children with polyostotic fibrous dysplasia of bone","volume":"88","author":"Plotkin","year":"2003","journal-title":"J Clin Endocrinol Metab"},{"issue":"3","key":"10.1016\/j.jcot.2025.103182_bib11","doi-asserted-by":"crossref","first-page":"410","DOI":"10.1067\/mpd.2000.107838","article-title":"Osteoporosis pseudoglioma syndrome: treatment of spinal osteoporosis with intravenous bisphosphonates","volume":"137","author":"Zacharin","year":"2000","journal-title":"J Pediatr"},{"issue":"2","key":"10.1016\/j.jcot.2025.103182_bib12","doi-asserted-by":"crossref","first-page":"188","DOI":"10.1111\/j.1651-2227.2000.tb01214.x","article-title":"Pamidronate treatment of bone fibrous dysplasia in nine children with McCune-Albright syndrome","volume":"89","author":"Lala","year":"2000","journal-title":"Acta Paediatr"},{"key":"10.1016\/j.jcot.2025.103182_bib13","doi-asserted-by":"crossref","DOI":"10.3389\/fped.2020.582316","article-title":"Response to zoledronic acid infusion in children with fibrous dysplasia","volume":"8","author":"Tripathy","year":"2020","journal-title":"Front Pediatr"},{"issue":"1","key":"10.1016\/j.jcot.2025.103182_bib14","doi-asserted-by":"crossref","first-page":"10","DOI":"10.1016\/j.jcms.2003.07.009","article-title":"Treatment of monostotic fibrous dysplasia with pamidronate","volume":"32","author":"Kos","year":"2004","journal-title":"J Cranio-Maxillofacial Surg"},{"issue":"1","key":"10.1016\/j.jcot.2025.103182_bib15","doi-asserted-by":"crossref","first-page":"139","DOI":"10.1186\/s13023-019-1102-9","article-title":"Best practice management guidelines for fibrous dysplasia\/McCune-Albright syndrome: a consensus statement from the FD\/MAS international consortium","volume":"14","author":"Javaid","year":"2019","journal-title":"Orphanet J Rare Dis"},{"issue":"3","key":"10.1016\/j.jcot.2025.103182_bib16","doi-asserted-by":"crossref","first-page":"2550","DOI":"10.3390\/ijms24032550","article-title":"Pharmacological interventions targeting pain in fibrous Dysplasia\/McCune\u2013Albright syndrome","volume":"24","author":"Tucker-Bartley","year":"2023","journal-title":"Int J Mol Sci"},{"issue":"3","key":"10.1016\/j.jcot.2025.103182_bib17","doi-asserted-by":"crossref","first-page":"223","DOI":"10.1111\/jpc.13768","article-title":"Consensus guidelines on the use of bisphosphonate therapy in children and adolescents","volume":"54","author":"Simm","year":"2018","journal-title":"J Paediatr Child Health"},{"key":"10.1016\/j.jcot.2025.103182_bib18","doi-asserted-by":"crossref","first-page":"60","DOI":"10.1016\/j.bone.2019.01.003","article-title":"Outcomes following intravenous bisphosphonate infusion in pediatric patients: a 7-year retrospective chart review","volume":"121","author":"Nasomyont","year":"2019","journal-title":"Bone"}],"container-title":["Journal of Clinical Orthopaedics and Trauma"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0976566225002802?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0976566225002802?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,28]],"date-time":"2025-10-28T02:38:44Z","timestamp":1761619124000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0976566225002802"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,11]]},"references-count":18,"alternative-id":["S0976566225002802"],"URL":"https:\/\/doi.org\/10.1016\/j.jcot.2025.103182","relation":{},"ISSN":["0976-5662"],"issn-type":[{"value":"0976-5662","type":"print"}],"subject":[],"published":{"date-parts":[[2025,11]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Bisphosphonate therapy in pediatric fibrous dysplasia: A systematic review of clinical, biochemical, and radiological outcomes","name":"articletitle","label":"Article Title"},{"value":"Journal of Clinical Orthopaedics and Trauma","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.jcot.2025.103182","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2025 Delhi Orthopedic Association. All rights are reserved, including those for text and data mining, AI training, and similar technologies.","name":"copyright","label":"Copyright"}],"article-number":"103182"}}