{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,10]],"date-time":"2026-02-10T18:11:22Z","timestamp":1770747082820,"version":"3.49.0"},"reference-count":30,"publisher":"Elsevier BV","issue":"1","license":[{"start":{"date-parts":[[2005,7,1]],"date-time":"2005-07-01T00:00:00Z","timestamp":1120176000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Journal of Comparative Pathology"],"published-print":{"date-parts":[[2005,7]]},"DOI":"10.1016\/j.jcpa.2005.01.004","type":"journal-article","created":{"date-parts":[[2005,5,18]],"date-time":"2005-05-18T11:58:45Z","timestamp":1116417525000},"page":"33-40","source":"Crossref","is-referenced-by-count":10,"title":["Observations on the Interstitial Cells of Cajal and Neurons in a Recovered Case of Equine Dysautonomia (Grass Sickness)"],"prefix":"10.1016","volume":"133","author":[{"given":"E.M.","family":"Milne","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"C.","family":"Fintl","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"N.P.H.","family":"Hudson","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"G.T.","family":"Pearson","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"I.G.","family":"Mayhew","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"C.N.","family":"Hahn","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.jcpa.2005.01.004_bib1","doi-asserted-by":"crossref","first-page":"555","DOI":"10.1111\/j.1469-7793.2001.0555c.xd","article-title":"Loss of interstitial cells of Cajal and development of electrical dysfunction in murine small bowel obstruction","volume":"536","author":"Chang","year":"2001","journal-title":"Journal of Physiology"},{"key":"10.1016\/j.jcpa.2005.01.004_bib2","doi-asserted-by":"crossref","first-page":"79","DOI":"10.1046\/j.1365-2982.1999.00140.x","article-title":"The neurology and enterology of equine grass sickness: a review of basic mechanisms","volume":"11","author":"Cottrell","year":"1999","journal-title":"Neurogastroenterology and Motility"},{"key":"10.1016\/j.jcpa.2005.01.004_bib3","doi-asserted-by":"crossref","first-page":"336","DOI":"10.1002\/(SICI)1097-4598(199803)21:3<336::AID-MUS7>3.0.CO;2-B","article-title":"Fasciculation potentials: a study of amyotrophic lateral sclerosis and other neurogenic disorders","volume":"21","author":"de Carvalho","year":"1998","journal-title":"Muscle Nerve"},{"key":"10.1016\/j.jcpa.2005.01.004_bib4","doi-asserted-by":"crossref","first-page":"1590","DOI":"10.1053\/gast.2000.20221","article-title":"Interstitial cells of Cajal and inflammation-induced motor dysfunction in the mouse small intestine","volume":"119","author":"Der","year":"2000","journal-title":"Gastroenterology"},{"key":"10.1016\/j.jcpa.2005.01.004_bib5","doi-asserted-by":"crossref","first-page":"645","DOI":"10.1136\/vr.146.22.645","article-title":"Histology in recovered cases of grass sickness","volume":"146","author":"Doxey","year":"2000","journal-title":"Veterinary Record"},{"key":"10.1016\/j.jcpa.2005.01.004_bib6","doi-asserted-by":"crossref","first-page":"585","DOI":"10.1136\/vr.137.8.181","article-title":"Recovery of horses from dysautonomia (grass sickness)","volume":"137","author":"Doxey","year":"1995","journal-title":"Veterinary Record"},{"key":"10.1016\/j.jcpa.2005.01.004_bib7","doi-asserted-by":"crossref","first-page":"433","DOI":"10.1007\/BF01839331","article-title":"The equine enteric nervous system\u2014neuron characterization and distribution in adults and juveniles","volume":"19","author":"Doxey","year":"1995","journal-title":"Veterinary Research Communications"},{"key":"10.1016\/j.jcpa.2005.01.004_bib8","doi-asserted-by":"crossref","first-page":"474","DOI":"10.2746\/0425164044877314","article-title":"The interstitial cells of Cajal (ICC) in equine colic: an immunohistochemical study of horses with obstructive disorders of the small and large intestines","volume":"36","author":"Fintl","year":"2004","journal-title":"Equine Veterinary Journal"},{"key":"10.1016\/j.jcpa.2005.01.004_bib9","doi-asserted-by":"crossref","first-page":"197","DOI":"10.1016\/S0034-5288(18)33828-1","article-title":"Observations on neuronal changes in grass sickness of horses","volume":"15","author":"Gilmour","year":"1973","journal-title":"Research in Veterinary Science"},{"key":"10.1016\/j.jcpa.2005.01.004_bib10","doi-asserted-by":"crossref","first-page":"603","DOI":"10.1136\/vr.147.21.603","article-title":"Phenylephrine eyedrops as a diagnostic test in equine grass sickness","volume":"147","author":"Hahn","year":"2000","journal-title":"Veterinary Record"},{"key":"10.1016\/j.jcpa.2005.01.004_bib11","doi-asserted-by":"crossref","first-page":"153","DOI":"10.1007\/s004010000289","article-title":"Central neuropathology of equine grass sickness","volume":"102","author":"Hahn","year":"2001","journal-title":"Acta Neuropathologica"},{"key":"10.1016\/j.jcpa.2005.01.004_bib12","doi-asserted-by":"crossref","first-page":"37","DOI":"10.1016\/S1566-0702(01)00316-2","article-title":"A reduction in interstitial cells of Cajal in horses with equine dysautonomia (grass sickness)","volume":"92","author":"Hudson","year":"2001","journal-title":"Autonomic Neuroscience"},{"key":"10.1016\/j.jcpa.2005.01.004_bib13","doi-asserted-by":"crossref","first-page":"119","DOI":"10.1016\/S1566-0702(02)00065-6","article-title":"Presence of in vitro electrical activity in the ileum of horses with enteric nervous system pathology: equine dysautonomia (grass sickness)","volume":"99","author":"Hudson","year":"2002","journal-title":"Autonomic Neuroscience"},{"key":"10.1016\/j.jcpa.2005.01.004_bib14","doi-asserted-by":"crossref","first-page":"265","DOI":"10.1053\/rvsc.1998.0297","article-title":"An immunohistochemical study of interstitial cells of Cajal (ICC) in the equine gastrointestinal tract","volume":"66","author":"Hudson","year":"1999","journal-title":"Research in Veterinary Science"},{"key":"10.1016\/j.jcpa.2005.01.004_bib15","doi-asserted-by":"crossref","first-page":"492","DOI":"10.1111\/j.2042-3306.1999.tb03857.x","article-title":"The association of Clostridium botulinum type C with equine grass sickness: a toxicoinfection?","volume":"31","author":"Hunter","year":"1999","journal-title":"Equine Veterinary Journal"},{"key":"10.1016\/j.jcpa.2005.01.004_bib16","unstructured":"Kitamura, N., Pearson, G.T., Cottrell, D.F., Hudson, N.P.H., McGorum, B.C. and Doxey, D.L. (1998). Immunohistochemical study of intestinal neurons in horses with and without grass sickness. Proceedings of the Equine Grass Sickness Fund 10th Anniversary Symposium, 10th October 1998, Moredun Foundation, Edinburgh."},{"key":"10.1016\/j.jcpa.2005.01.004_bib17","doi-asserted-by":"crossref","first-page":"123","DOI":"10.2746\/0425164044868611","article-title":"Equine grass sickness is associated with low antibody levels to Clostridium botulinum: a matched case-control study","volume":"36","author":"McCarthy","year":"2004","journal-title":"Equine Veterinary Journal"},{"key":"10.1016\/j.jcpa.2005.01.004_bib18","unstructured":"Milne, E.M. (1997). Clinical aspects and treatment of grass sickness in the UK. Proceedings of the 1st International Workshop on Grass Sickness, EMND and Related Disorders, Bern, 26\u201327th October 1995. Equine Veterinary Journal, June 1997, 1\u20133."},{"key":"10.1016\/j.jcpa.2005.01.004_bib19","doi-asserted-by":"crossref","first-page":"217","DOI":"10.1111\/j.2042-3292.1994.tb01139.x","article-title":"Nursing the chronic grass sickness patient","volume":"6","author":"Milne","year":"1994","journal-title":"Equine Veterinary Education"},{"key":"10.1016\/j.jcpa.2005.01.004_bib20","doi-asserted-by":"crossref","first-page":"438","DOI":"10.1136\/vr.134.17.438","article-title":"Use of clinical measurements to predict outcome in chronic cases of grass sickness (equine dysautonomia)","volume":"143","author":"Milne","year":"1994","journal-title":"Veterinary Record"},{"key":"10.1016\/j.jcpa.2005.01.004_bib21","doi-asserted-by":"crossref","first-page":"597","DOI":"10.1136\/vr.153.19.597","article-title":"Complete clinical recovery of a pony with histologically confirmed chronic grass sickness","volume":"153","author":"Owen","year":"2003","journal-title":"Veterinary Record"},{"key":"10.1016\/j.jcpa.2005.01.004_bib22","doi-asserted-by":"crossref","first-page":"271","DOI":"10.1016\/0021-9975(92)90003-D","article-title":"Autonomic neurone degeneration in equine dyseutonomia (grass sickness)","volume":"107","author":"Pogson","year":"1992","journal-title":"Journal of Comparative Pathology"},{"key":"10.1016\/j.jcpa.2005.01.004_bib23","doi-asserted-by":"crossref","first-page":"3043","DOI":"10.1128\/MCB.11.6.3043","article-title":"The steel\/w transduction pathway: Kit autophosphorylation and its association with a unique subset of cytoplasmic signaling proteins is induced by the steel factor","volume":"11","author":"Rottapel","year":"1991","journal-title":"Molecular and Cellular Biology"},{"key":"10.1016\/j.jcpa.2005.01.004_bib24","doi-asserted-by":"crossref","first-page":"492","DOI":"10.1053\/gast.1996.v111.pm8690216","article-title":"A case for interstitial cells of Cajal as pacemakers and mediators of neurotransmission in the gastrointestinal tract","volume":"111","author":"Sanders","year":"1996","journal-title":"Gastroenterology"},{"key":"10.1016\/j.jcpa.2005.01.004_bib25","doi-asserted-by":"crossref","first-page":"311","DOI":"10.1046\/j.1365-2982.1999.00164.x","article-title":"Development and plasticity of interstitial cells of Cajal","volume":"11","author":"Sanders","year":"1999","journal-title":"Neurogastroenterology and Motility"},{"key":"10.1016\/j.jcpa.2005.01.004_bib26","doi-asserted-by":"crossref","first-page":"7","DOI":"10.1136\/vr.133.1.7","article-title":"Diagnosis of grass sickness by ileal biopsy","volume":"133","author":"Scholes","year":"1993","journal-title":"Veterinary Record"},{"key":"10.1016\/j.jcpa.2005.01.004_bib27","doi-asserted-by":"crossref","first-page":"344","DOI":"10.1002\/(SICI)1097-0029(19991201)47:5<344::AID-JEMT6>3.0.CO;2-1","article-title":"Interstitial cells of Cajal in human gut and gastrointestinal disease","volume":"47","author":"Vanderwinden","year":"1999","journal-title":"Microscopy Research and Technique"},{"key":"10.1016\/j.jcpa.2005.01.004_bib28","doi-asserted-by":"crossref","first-page":"1529","DOI":"10.1016\/S0002-9440(10)62579-5","article-title":"Pathology of the interstitial cells of Cajal in relation to inflammation revealed by ultrastructure but not immunohistochemistry","volume":"160","author":"Wang","year":"2002","journal-title":"American Journal of Pathology"},{"key":"10.1016\/j.jcpa.2005.01.004_bib29","unstructured":"Whitwell, K. (1997). Histopathology of grass sickness\u2014comparative aspects of dysautonomia in various species (equine, feline, canine, leporids). Proceedings of the 1st International Workshop on Grass Sickness, EMND and Related Disorders, Bern, 26\u201327th October 1995. Equine Veterinary Journal, June 1997, 18\u201322."},{"key":"10.1016\/j.jcpa.2005.01.004_bib30","unstructured":"Wijnberg, I. (2003). The practical application of EMG needle examination in the horse. Proceedings of the British Equine Veterinary Association Congress, Birmingham, pp. 174\u2013176."}],"container-title":["Journal of Comparative Pathology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0021997505000216?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0021997505000216?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2020,4,7]],"date-time":"2020-04-07T10:46:00Z","timestamp":1586256360000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0021997505000216"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2005,7]]},"references-count":30,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2005,7]]}},"alternative-id":["S0021997505000216"],"URL":"https:\/\/doi.org\/10.1016\/j.jcpa.2005.01.004","relation":{},"ISSN":["0021-9975"],"issn-type":[{"value":"0021-9975","type":"print"}],"subject":[],"published":{"date-parts":[[2005,7]]}}}