{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,9,21]],"date-time":"2025-09-21T17:59:54Z","timestamp":1758477594390},"reference-count":12,"publisher":"Elsevier BV","issue":"4","license":[{"start":{"date-parts":[[2005,11,1]],"date-time":"2005-11-01T00:00:00Z","timestamp":1130803200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Journal of Comparative Pathology"],"published-print":{"date-parts":[[2005,11]]},"DOI":"10.1016\/j.jcpa.2005.05.002","type":"journal-article","created":{"date-parts":[[2005,11,5]],"date-time":"2005-11-05T07:37:57Z","timestamp":1131176277000},"page":"286-288","source":"Crossref","is-referenced-by-count":6,"title":["Diminazene Aceturate Resistance on the Virulence of Trypanosoma brucei for Rats"],"prefix":"10.1016","volume":"133","author":[{"given":"T.N.","family":"Egbe-Nwiyi","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"I.O.","family":"Igbokwe","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"P.A.","family":"Onyeyili","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.jcpa.2005.05.002_bib1","series-title":"A field guide for diagnosis treatment and prevention of African animal trypanosomiasis","author":"Boyt","year":"1986"},{"key":"10.1016\/j.jcpa.2005.05.002_bib2","series-title":"A course in applied statistics","first-page":"134","article-title":"Statistics for technology","author":"Chatfield","year":"1983"},{"key":"10.1016\/j.jcpa.2005.05.002_bib3","unstructured":"Egbe-Nwiyi TN, Studies on some factors affecting the pathogenicity of trypanosome infections in rats, PhD Thesis, University of Maiduguri, Nigeria; 2002."},{"key":"10.1016\/j.jcpa.2005.05.002_bib4","first-page":"37","article-title":"Relapses in experimental canine trypanosomiasis with special reference to the effect of splenectomy","volume":"51","author":"Egbe-Nwiyi","year":"1996","journal-title":"Israel J Veterinary Med"},{"key":"10.1016\/j.jcpa.2005.05.002_bib5","doi-asserted-by":"crossref","first-page":"188","DOI":"10.1053\/jcpa.2002.0599","article-title":"The pathogenicity of diminazene aceturate-resistant Trypanosoma brucei in rats after treatment with the drug","volume":"128","author":"Egbe-Nwiyi","year":"2003","journal-title":"J Comparative Pathol"},{"key":"10.1016\/j.jcpa.2005.05.002_bib6","series-title":"The programme against African Trypanosomiasis","article-title":"Drug management and parasite resistance in bovine trypanosomiasis in Africa","author":"Geerts","year":"1998"},{"key":"10.1016\/j.jcpa.2005.05.002_bib7","doi-asserted-by":"crossref","first-page":"281","DOI":"10.1042\/bj2720281","article-title":"Molecular mechanism of drug resistance","volume":"272","author":"Hayes","year":"1990","journal-title":"Biochem J"},{"key":"10.1016\/j.jcpa.2005.05.002_bib8","first-page":"7","article-title":"International livestock Research Institute","volume":"2","year":"1996","journal-title":"Newsletter"},{"key":"10.1016\/j.jcpa.2005.05.002_bib9","first-page":"82","article-title":"Studies on the chemotherapeutic control of animal trypanosomiasis in Nigeria","volume":"3","author":"Kalu","year":"1995","journal-title":"J Pasteur Inst (Romania)"},{"key":"10.1016\/j.jcpa.2005.05.002_bib10","doi-asserted-by":"crossref","first-page":"505","DOI":"10.1111\/j.1748-5827.1989.tb01621.x","article-title":"Chemotherapy of T.b. brucei infection, use of DFMO, diminazene aceturate alone and in combination","volume":"30","author":"Onyeyili","year":"1989","journal-title":"J Small Animal Practice"},{"key":"10.1016\/j.jcpa.2005.05.002_bib11","first-page":"143","article-title":"Efficacy of combination of DFMO and diminazene aceturate in the treatment of late stage Trypanosoma brucei brucei infection in rats","volume":"42","author":"Onyeyili","year":"1991","journal-title":"Trop Med Parasitol"},{"key":"10.1016\/j.jcpa.2005.05.002_bib12","first-page":"20","article-title":"Veterinanry haematology","author":"Schalm","year":"1975"}],"container-title":["Journal of Comparative Pathology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0021997505000642?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0021997505000642?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2019,1,21]],"date-time":"2019-01-21T02:59:17Z","timestamp":1548039557000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0021997505000642"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2005,11]]},"references-count":12,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2005,11]]}},"alternative-id":["S0021997505000642"],"URL":"https:\/\/doi.org\/10.1016\/j.jcpa.2005.05.002","relation":{},"ISSN":["0021-9975"],"issn-type":[{"value":"0021-9975","type":"print"}],"subject":[],"published":{"date-parts":[[2005,11]]}}}