{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,21]],"date-time":"2026-03-21T18:49:08Z","timestamp":1774118948694,"version":"3.50.1"},"reference-count":43,"publisher":"Elsevier BV","issue":"2-3","license":[{"start":{"date-parts":[[2011,8,1]],"date-time":"2011-08-01T00:00:00Z","timestamp":1312156800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Journal of Comparative Pathology"],"published-print":{"date-parts":[[2011,8]]},"DOI":"10.1016\/j.jcpa.2011.01.002","type":"journal-article","created":{"date-parts":[[2011,3,9]],"date-time":"2011-03-09T14:58:52Z","timestamp":1299682732000},"page":"251-260","source":"Crossref","is-referenced-by-count":13,"title":["Pathology, Tissue Metalloproteinase Transcription and Haptoglobin Responses in Mice after Experimental Challenge with Different Isolates of Pasteurella multocida Obtained from Cases of Porcine Pneumonia"],"prefix":"10.1016","volume":"145","author":[{"given":"S.E.","family":"Pors","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"M.S.","family":"Chadfield","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"D.B.","family":"S\u00f8rensen","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"H.","family":"Offenberg","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"P.M.H.","family":"Heegaard","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"M.","family":"Bisgaard","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"H.E.","family":"Jensen","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.jcpa.2011.01.002_bib1","doi-asserted-by":"crossref","first-page":"1919","DOI":"10.1128\/AEM.56.6.1919-1925.1990","article-title":"Combination of 16S rRNA-targeted oligonucleotide probes with flow cytometry for analyzing mixed microbial populations","volume":"56","author":"Amann","year":"1990","journal-title":"Applied Environmental Microbiology"},{"key":"10.1016\/j.jcpa.2011.01.002_bib2","doi-asserted-by":"crossref","first-page":"102","DOI":"10.2460\/javma.1994.204.01.102","article-title":"Interaction of Mycoplasma hyopneumoniae and Pasteurella multocida infections in swine","volume":"204","author":"Amass","year":"1994","journal-title":"Journal of the American Veterinary Medical Association"},{"key":"10.1016\/j.jcpa.2011.01.002_bib3","first-page":"205","article-title":"Cytokine mRNA expression in experimental porcine pneumonia","volume":"109","author":"Berndt","year":"2002","journal-title":"Deutsche Tieraerztliche Wochenschrift"},{"key":"10.1016\/j.jcpa.2011.01.002_bib4","doi-asserted-by":"crossref","first-page":"355","DOI":"10.1016\/S0378-1135(97)00111-9","article-title":"Phenotypic characterisation of Pasteurella multocida isolates from Australian pigs","volume":"57","author":"Blackall","year":"1997","journal-title":"Veterinary Microbiology"},{"key":"10.1016\/j.jcpa.2011.01.002_bib5","doi-asserted-by":"crossref","first-page":"463","DOI":"10.1637\/7151","article-title":"Pasteurella multocida infection in heterophil-depleted chickens","volume":"48","author":"Bojesen","year":"2004","journal-title":"Avian Diseases"},{"key":"10.1016\/j.jcpa.2011.01.002_bib6","doi-asserted-by":"crossref","first-page":"287","DOI":"10.1111\/j.1439-0442.1991.tb01015.x","article-title":"Statistical evidence for a link between bronchopneumonia and disseminated focal nephritis in pigs","volume":"38","author":"Buttenschon","year":"1991","journal-title":"Zentralblatt fur Veterinarmedizin. Reihe A"},{"key":"10.1016\/j.jcpa.2011.01.002_bib7","doi-asserted-by":"crossref","first-page":"364","DOI":"10.1002\/jlb.50.4.364","article-title":"Porcine alveolar and pulmonary intravascular macrophages: comparison of immune functions","volume":"50","author":"Chitko-McKown","year":"1991","journal-title":"Journal of Leukocyte Biology"},{"key":"10.1016\/j.jcpa.2011.01.002_bib8","first-page":"1","article-title":"The prevalence of pneumonia, pleuritis, pericarditis and liver spots in Danish slaughter pigs in 1998, including comparison with 1994","volume":"82","author":"Christensen","year":"1999","journal-title":"Dansk Veterin\u00e6rtidskrift"},{"key":"10.1016\/j.jcpa.2011.01.002_bib9","first-page":"434","article-title":"Mycoplasma hyopneumoniae increases the susceptibility of pigs to experimental Pasteurella multocida pneumonia","volume":"52","author":"Ciprian","year":"1988","journal-title":"Canadian Journal of Veterinary Research"},{"key":"10.1016\/j.jcpa.2011.01.002_bib10","doi-asserted-by":"crossref","first-page":"868","DOI":"10.1128\/IAI.8.6.868-875.1973","article-title":"Growth of Pasteurella multocida in vaccinated and normal mice","volume":"8","author":"Collins","year":"1973","journal-title":"Infection and Immunity"},{"key":"10.1016\/j.jcpa.2011.01.002_bib11","author":"Danish Meat Association"},{"key":"10.1016\/j.jcpa.2011.01.002_bib12","doi-asserted-by":"crossref","first-page":"1446","DOI":"10.2460\/ajvr.1987.48.10.1446","article-title":"Pneumonia in pigs induced by intranasal challenge exposure with pseudorabies virus and Pasteurella multocida","volume":"48","author":"Fuentes","year":"1987","journal-title":"American Journal of Veterinary Research"},{"key":"10.1016\/j.jcpa.2011.01.002_bib13","doi-asserted-by":"crossref","first-page":"205","DOI":"10.1111\/j.1439-0450.1975.tb00581.x","article-title":"Incidence and evaluation of the microbial flora in the lungs of pigs with enzootic pneumonia","volume":"22","author":"Gois","year":"1975","journal-title":"Zentralblatt fur Veterinarmedizin. Reihe B"},{"key":"10.1016\/j.jcpa.2011.01.002_bib14","doi-asserted-by":"crossref","first-page":"120","DOI":"10.1016\/j.jcpa.2010.01.012","article-title":"An investigation of the pathology and pathogens associated with porcine respiratory disease complex in Denmark","volume":"143","author":"Hansen","year":"2010","journal-title":"Journal of Comparative Pathology"},{"key":"10.1016\/j.jcpa.2011.01.002_bib15","doi-asserted-by":"crossref","first-page":"395","DOI":"10.1186\/BF03546970","article-title":"An abattoir survey of pneumonia and pleuritis in slaughter weight swine from 9 selected herds. IV. Bacteriological findings in chronic pneumonic lesions","volume":"32","author":"Hoie","year":"1991","journal-title":"Acta Veterinaria Scandinavica"},{"key":"10.1016\/j.jcpa.2011.01.002_bib16","doi-asserted-by":"crossref","first-page":"1200","DOI":"10.1292\/jvms1939.50.1200","article-title":"Relationship between serotypes, dermonecrotic toxin production of Pasteurella multocida isolates and pneumonic lesions of porcine lung","volume":"50","author":"Iwamatsu","year":"1988","journal-title":"Nippon Juigaku Zasshi"},{"key":"10.1016\/j.jcpa.2011.01.002_bib17","doi-asserted-by":"crossref","first-page":"251","DOI":"10.1016\/S1090-0233(02)00257-5","article-title":"Association of porcine circovirus 2 with porcine respiratory disease complex","volume":"166","author":"Kim","year":"2003","journal-title":"Veterinary Journal"},{"key":"10.1016\/j.jcpa.2011.01.002_bib18","first-page":"364","article-title":"Immunological roles of Pasteurella multocida toxin (PMT) using a PMT mutant strain","volume":"45","author":"Kim","year":"2007","journal-title":"Journal of Microbiology"},{"key":"10.1016\/j.jcpa.2011.01.002_bib19","first-page":"195","article-title":"Evaluation of subcutaneously-implanted glucose sensors for continuous glucose measurements in hyperglycemic pigs","volume":"20","author":"Kvist","year":"2006","journal-title":"In Vivo"},{"key":"10.1016\/j.jcpa.2011.01.002_bib20","series-title":"Manual of Histologic Staining Methods of the Armed Forces Institute of Pathology","author":"Luna","year":"1968"},{"key":"10.1016\/j.jcpa.2011.01.002_bib21","doi-asserted-by":"crossref","first-page":"227","DOI":"10.1111\/j.1751-0813.1992.tb09931.x","article-title":"Pasteurella multocida septicaemia in pigs","volume":"69","author":"Mackie","year":"1992","journal-title":"Australian Veterinary Journal"},{"key":"10.1016\/j.jcpa.2011.01.002_bib22","doi-asserted-by":"crossref","first-page":"2627","DOI":"10.1128\/JCM.39.7.2627-2633.2001","article-title":"Specific detection of Pasteurella multocida in chickens with fowl cholera and in pig lung tissues using fluorescent rRNA in-situ hybridization","volume":"39","author":"Mbuthia","year":"2001","journal-title":"Journal of Clinical Microbiology"},{"key":"10.1016\/j.jcpa.2011.01.002_bib23","doi-asserted-by":"crossref","first-page":"123","DOI":"10.1006\/smim.2001.0349","article-title":"Molecular mechanisms of neutrophil recruitment elicited by bacteria in the lungs","volume":"14","author":"Mizgerd","year":"2002","journal-title":"Seminars in Immunology"},{"key":"10.1016\/j.jcpa.2011.01.002_bib24","doi-asserted-by":"crossref","first-page":"716","DOI":"10.1056\/NEJMra074111","article-title":"Acute lower respiratory tract infection","volume":"358","author":"Mizgerd","year":"2008","journal-title":"New England Journal of Medicine"},{"key":"10.1016\/j.jcpa.2011.01.002_bib25","doi-asserted-by":"crossref","first-page":"21","DOI":"10.1097\/01.moh.0000190113.31027.d5","article-title":"Neutrophil granule contents in the pathogenesis of lung injury","volume":"13","author":"Moraes","year":"2006","journal-title":"Current Opinion in Hematology"},{"key":"10.1016\/j.jcpa.2011.01.002_bib26","first-page":"129","article-title":"Microorganisms associated with pneumonia in slaughter weight swine","volume":"49","author":"Morrison","year":"1985","journal-title":"Canadian Journal of Comparative Medicine"},{"key":"10.1016\/j.jcpa.2011.01.002_bib27","doi-asserted-by":"crossref","first-page":"251","DOI":"10.1016\/S0021-9975(03)00040-9","article-title":"Septicaemia and arthritis in pigs experimentally infected with Pasteurella multocida capsular serotype A","volume":"129","author":"Ono","year":"2003","journal-title":"Journal of Comparative Pathology"},{"key":"10.1016\/j.jcpa.2011.01.002_bib28","doi-asserted-by":"crossref","first-page":"369","DOI":"10.1016\/j.tvjl.2007.04.019","article-title":"Relationship between serum acute phase protein concentrations and lesions in finishing pigs","volume":"177","author":"Pallares","year":"2008","journal-title":"Veterinary Journal"},{"key":"10.1016\/j.jcpa.2011.01.002_bib29","doi-asserted-by":"crossref","first-page":"267","DOI":"10.1136\/vr.162.9.267","article-title":"Associations between pathogens in healthy pigs and pigs with pneumonia","volume":"162","author":"Palzer","year":"2008","journal-title":"Veterinary Record"},{"key":"10.1016\/j.jcpa.2011.01.002_bib30","doi-asserted-by":"crossref","first-page":"617","DOI":"10.1038\/nri1418","article-title":"Matrix metalloproteinases as modulators of inflammation and innate immunity","volume":"4","author":"Parks","year":"2004","journal-title":"Nature Reviews Immunology"},{"key":"10.1016\/j.jcpa.2011.01.002_bib31","doi-asserted-by":"crossref","first-page":"1703","DOI":"10.1126\/science.158.3809.1703","article-title":"Haptoglobin levels in serum of various strains of mice","volume":"158","author":"Peacock","year":"1967","journal-title":"Science"},{"key":"10.1016\/j.jcpa.2011.01.002_bib32","doi-asserted-by":"crossref","first-page":"163","DOI":"10.1051\/vetres:2004002","article-title":"Application of acute phase protein measurements in veterinary clinical chemistry","volume":"35","author":"Petersen","year":"2004","journal-title":"Veterinary Research"},{"key":"10.1016\/j.jcpa.2011.01.002_bib33","series-title":"Diseases of Swine","first-page":"719","article-title":"Pneumonic pasteurellosis","author":"Pijoan","year":"2006"},{"key":"10.1016\/j.jcpa.2011.01.002_bib34","doi-asserted-by":"crossref","first-page":"823","DOI":"10.2460\/javma.1987.191.07.823","article-title":"Severe pleuritis associated with certain strains of Pasteurella multocida in swine","volume":"191","author":"Pijoan","year":"1987","journal-title":"Journal of the American Veterinary Medical Association"},{"key":"10.1016\/j.jcpa.2011.01.002_bib35","first-page":"306","article-title":"Influence of Pasteurella multocida and Mycoplasma hyorhinis (PPLO) on the histopathology of field case of swine pneumonia","volume":"52","author":"Roberts","year":"1962","journal-title":"Cornell Veterinarian"},{"key":"10.1016\/j.jcpa.2011.01.002_bib36","doi-asserted-by":"crossref","first-page":"13","DOI":"10.1017\/S1466252307001211","article-title":"Pasteurella multocida and its role in porcine pneumonia","volume":"7","author":"Ross","year":"2006","journal-title":"Animal Health Research Reviews"},{"key":"10.1016\/j.jcpa.2011.01.002_bib37","doi-asserted-by":"crossref","first-page":"822","DOI":"10.1099\/0022-1317-50-9-822","article-title":"Impairment of host defence by exotoxin A in Pseudomonas aeruginosa pneumonia in mice","volume":"50","author":"Schultz","year":"2001","journal-title":"Journal of Medical Microbiology"},{"key":"10.1016\/j.jcpa.2011.01.002_bib38","first-page":"551","article-title":"Immunology of the porcine respiratory disease complex","volume":"17","author":"Thacker","year":"2001","journal-title":"Veterinary Clinics of North America"},{"key":"10.1016\/j.jcpa.2011.01.002_bib39","doi-asserted-by":"crossref","first-page":"469","DOI":"10.1051\/vetres:2006011","article-title":"Lung inflammatory responses","volume":"37","author":"Thacker","year":"2006","journal-title":"Veterinary Research"},{"key":"10.1016\/j.jcpa.2011.01.002_bib40","doi-asserted-by":"crossref","first-page":"353","DOI":"10.1182\/blood-2005-09-3890","article-title":"Haptoglobin is synthesized during granulocyte differentiation, stored in specific granules, and released by neutrophils in response to activation","volume":"108","author":"Theilgaard-Monch","year":"2006","journal-title":"Blood"},{"key":"10.1016\/j.jcpa.2011.01.002_bib41","doi-asserted-by":"crossref","first-page":"525","DOI":"10.1007\/BF00931575","article-title":"Interaction between Ascaris suum and Pasteurella multocida in the lungs of mice","volume":"78","author":"Tjornehoj","year":"1992","journal-title":"Parasitology Research"},{"key":"10.1016\/j.jcpa.2011.01.002_bib42","doi-asserted-by":"crossref","first-page":"205","DOI":"10.1016\/S0378-1135(98)00233-8","article-title":"Acute septicaemic pasteurellosis in Vietnamese pigs","volume":"63","author":"Townsend","year":"1998","journal-title":"Veterinary Microbiology"},{"key":"10.1016\/j.jcpa.2011.01.002_bib43","doi-asserted-by":"crossref","first-page":"1040","DOI":"10.1128\/IAI.01313-06","article-title":"Surface proteins and exotoxins are required for the pathogenesis of Staphylococcus aureus pneumonia","volume":"75","author":"Wardenburg","year":"2007","journal-title":"Infection and Immunity"}],"container-title":["Journal of Comparative Pathology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0021997511000053?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0021997511000053?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,3,3]],"date-time":"2025-03-03T22:38:11Z","timestamp":1741041491000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0021997511000053"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2011,8]]},"references-count":43,"journal-issue":{"issue":"2-3","published-print":{"date-parts":[[2011,8]]}},"alternative-id":["S0021997511000053"],"URL":"https:\/\/doi.org\/10.1016\/j.jcpa.2011.01.002","relation":{},"ISSN":["0021-9975"],"issn-type":[{"value":"0021-9975","type":"print"}],"subject":[],"published":{"date-parts":[[2011,8]]}}}