{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,20]],"date-time":"2026-01-20T02:29:44Z","timestamp":1768876184012,"version":"3.49.0"},"reference-count":29,"publisher":"Elsevier BV","issue":"4","license":[{"start":{"date-parts":[[2017,11,1]],"date-time":"2017-11-01T00:00:00Z","timestamp":1509494400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2017,11,1]],"date-time":"2017-11-01T00:00:00Z","timestamp":1509494400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Journal of Comparative Pathology"],"published-print":{"date-parts":[[2017,11]]},"DOI":"10.1016\/j.jcpa.2017.09.002","type":"journal-article","created":{"date-parts":[[2017,10,12]],"date-time":"2017-10-12T12:16:26Z","timestamp":1507810586000},"page":"270-275","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":8,"title":["120 years of Louping-ill Research: an Historical Perspective from the Archive of the Journal of Comparative Pathology"],"prefix":"10.1016","volume":"157","author":[{"given":"D.","family":"Buxton","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"H.W.","family":"Reid","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.jcpa.2017.09.002_bib1","series-title":"A History of the Animal Diseases Research Association, 1920\u20131990","author":"Angus","year":"1990"},{"key":"10.1016\/j.jcpa.2017.09.002_bib2","doi-asserted-by":"crossref","first-page":"377","DOI":"10.1016\/0021-9975(70)90068-X","article-title":"Development of a non-infective protective antigen against louping-ill (arbovirus group B): laboratory experiments","volume":"80","author":"Brotherston","year":"1970","journal-title":"Journal of Comparative Pathology"},{"key":"10.1016\/j.jcpa.2017.09.002_bib3","doi-asserted-by":"crossref","first-page":"67","DOI":"10.1016\/S0368-1742(32)80006-8","article-title":"Studies in the histopathology of louping-ill","volume":"45","author":"Brownlee","year":"1932","journal-title":"Journal of Comparative Pathology and Therapeutics"},{"key":"10.1016\/j.jcpa.2017.09.002_bib4","doi-asserted-by":"crossref","first-page":"231","DOI":"10.1016\/0021-9975(75)90064-X","article-title":"Experimental infection of red grouse with louping-ill virus (Flavivirus group). II. Neuropathology","volume":"85","author":"Buxton","year":"1975","journal-title":"Journal of Comparative Pathology"},{"key":"10.1016\/j.jcpa.2017.09.002_bib5","doi-asserted-by":"crossref","first-page":"331","DOI":"10.1016\/0021-9975(71)90020-X","article-title":"Experimental louping-ill in sheep and lambs. II Neuropathology","volume":"81","author":"Doherty","year":"1971","journal-title":"Journal of Comparative Pathology"},{"key":"10.1016\/j.jcpa.2017.09.002_bib6","doi-asserted-by":"crossref","first-page":"531","DOI":"10.1016\/0021-9975(71)90081-8","article-title":"Louping-ill encephalomyelitis in the sheep. II. Distribution of virus and lesions in nervous tissue","volume":"81","author":"Doherty","year":"1971","journal-title":"Journal of Comparative Pathology"},{"key":"10.1016\/j.jcpa.2017.09.002_bib7","doi-asserted-by":"crossref","first-page":"545","DOI":"10.1016\/0021-9975(71)90083-1","article-title":"Louping-ill encephalomyelitis in the sheep. IV. Nature of the perivascular inflammatory reaction","volume":"81","author":"Doherty","year":"1971","journal-title":"Journal of Comparative Pathology"},{"key":"10.1016\/j.jcpa.2017.09.002_bib8","doi-asserted-by":"crossref","first-page":"337","DOI":"10.1016\/0021-9975(72)90015-1","article-title":"Louping-ill encephalomyelitis in the sheep. V. Histopathogenesis of the fatal disease","volume":"82","author":"Doherty","year":"1972","journal-title":"Journal of Comparative Pathology"},{"key":"10.1016\/j.jcpa.2017.09.002_bib9","first-page":"516","article-title":"Advances in veterinary research; louping-ill, tick-borne fever and scrapie","volume":"47","author":"Gordon","year":"1946","journal-title":"Veterinary Record"},{"key":"10.1016\/j.jcpa.2017.09.002_bib10","doi-asserted-by":"crossref","first-page":"106","DOI":"10.1016\/S0368-1742(32)80008-1","article-title":"Studies in louping-ill: an encephalomyelitis of sheep","volume":"45","author":"Gordon","year":"1932","journal-title":"Journal of Comparative Pathology and Therapeutics"},{"key":"10.1016\/j.jcpa.2017.09.002_bib11","doi-asserted-by":"crossref","first-page":"301","DOI":"10.1016\/S0368-1742(32)80025-1","article-title":"Tick-borne fever: a hitherto undescribed disease of sheep","volume":"45","author":"Gordon","year":"1932","journal-title":"Journal of Comparative Pathology and Therapeutics"},{"key":"10.1016\/j.jcpa.2017.09.002_bib12","series-title":"The Ettrick Shepherd","author":"Hogg","year":"1807"},{"key":"10.1016\/j.jcpa.2017.09.002_bib13","doi-asserted-by":"crossref","first-page":"231","DOI":"10.1016\/S0368-1742(31)80029-3","article-title":"The transmission of \u2018louping-ill\u2019 to the mouse and the monkey: histology of the experimental disease","volume":"44","author":"Hurst","year":"1931","journal-title":"Journal of Comparative Pathology and Therapeutics"},{"key":"10.1016\/j.jcpa.2017.09.002_bib14","doi-asserted-by":"crossref","first-page":"240","DOI":"10.1016\/S0368-1742(32)80022-6","article-title":"Studies in louping-ill, an encephalomyelitis of sheep. II. Transmission by the sheep tick, Ixodes ricinus L","volume":"45","author":"MacLeod","year":"1932","journal-title":"Journal of Comparative Pathology and Therapeutics"},{"key":"10.1016\/j.jcpa.2017.09.002_bib15","doi-asserted-by":"crossref","first-page":"411","DOI":"10.1016\/S0368-1742(62)80046-0","article-title":"Observations on tick-transmission of louping-ill to sheep","volume":"72","author":"MacLeod","year":"1962","journal-title":"Journal of Comparative Pathology"},{"key":"10.1016\/j.jcpa.2017.09.002_bib16","doi-asserted-by":"crossref","first-page":"207","DOI":"10.1016\/S0368-1742(94)80052-9","article-title":"Louping-ill in sheep","volume":"7","author":"M'Fadyean","year":"1894","journal-title":"Journal of Comparative Pathology and Therapeutics"},{"key":"10.1016\/j.jcpa.2017.09.002_bib17","doi-asserted-by":"crossref","first-page":"145","DOI":"10.1016\/S0368-1742(00)80026-0","article-title":"The etiology of louping-ill","volume":"13","author":"M'Fadyean","year":"1900","journal-title":"Journal of Comparative Pathology and Therapeutics"},{"key":"10.1016\/j.jcpa.2017.09.002_bib18","doi-asserted-by":"crossref","first-page":"253","DOI":"10.1016\/S0368-1742(30)80026-2","article-title":"The etiology of \u2018louping-ill\u2019","volume":"43","author":"Pool","year":"1930","journal-title":"Journal of Comparative Pathology and Therapeutics"},{"key":"10.1016\/j.jcpa.2017.09.002_bib19","doi-asserted-by":"crossref","first-page":"223","DOI":"10.1016\/0021-9975(75)90063-8","article-title":"Experimental infection of red grouse with louping-ill virus (Flavivirus group). I. Viraemia and antibody response","volume":"85","author":"Reid","year":"1975","journal-title":"Journal of Comparative Pathology"},{"key":"10.1016\/j.jcpa.2017.09.002_bib20","first-page":"197","article-title":"Monks, ticks and the molecular clock","volume":"46","author":"Reid","year":"1999","journal-title":"Biology"},{"key":"10.1016\/j.jcpa.2017.09.002_bib25","doi-asserted-by":"crossref","first-page":"181","DOI":"10.1016\/0021-9975(82)90076-7","article-title":"Immunosuppression in toxoplasmosis: studies in lambs and sheep infected with louping-ill virus","volume":"92","author":"Reid","year":"1982","journal-title":"Journal of Comparative Pathology"},{"key":"10.1016\/j.jcpa.2017.09.002_bib26","doi-asserted-by":"crossref","first-page":"56","DOI":"10.1016\/S0034-5288(18)30572-1","article-title":"Response of sheep to experimental concurrent infection with tick-borne fever (Cytoecetes phagocytophila) and louping-ill virus","volume":"41","author":"Reid","year":"1986","journal-title":"Research in Veterinary Science"},{"key":"10.1016\/j.jcpa.2017.09.002_bib21","doi-asserted-by":"crossref","first-page":"291","DOI":"10.1016\/0021-9975(71)90103-4","article-title":"Experimental louping-ill in sheep and lambs. I. Viraemia and antibody response","volume":"81","author":"Reid","year":"1971","journal-title":"Journal of Comparative Pathology"},{"key":"10.1016\/j.jcpa.2017.09.002_bib22","doi-asserted-by":"crossref","first-page":"521","DOI":"10.1016\/0021-9975(71)90080-6","article-title":"Louping-ill encephalomyelitis in the sheep. I. The relationship of viraemia and the antibody response to susceptibility","volume":"81","author":"Reid","year":"1971","journal-title":"Journal of Comparative Pathology"},{"key":"10.1016\/j.jcpa.2017.09.002_bib23","doi-asserted-by":"crossref","first-page":"537","DOI":"10.1016\/0021-9975(71)90082-X","article-title":"Louping-ill encephalomyelitis in the sheep. III. Immunoglobulins in cerebrospinal fluid","volume":"81","author":"Reid","year":"1971","journal-title":"Journal of Comparative Pathology"},{"key":"10.1016\/j.jcpa.2017.09.002_bib24","doi-asserted-by":"crossref","first-page":"257","DOI":"10.1016\/0021-9975(80)90062-6","article-title":"The response of three grouse species (Tetrao urogallus, Lagopus mutus, Lagopus lagopus) to louping-ill virus","volume":"90","author":"Reid","year":"1980","journal-title":"Journal of Comparative Pathology"},{"key":"10.1016\/j.jcpa.2017.09.002_bib27","doi-asserted-by":"crossref","first-page":"400","DOI":"10.1016\/j.jcpa.2017.03.003","article-title":"Lambs are susceptible to experimental challenge with Spanish goat encephalitis virus","volume":"156","author":"Salinas","year":"2017","journal-title":"Journal of Comparative Pathology"},{"key":"10.1016\/j.jcpa.2017.09.002_bib28","doi-asserted-by":"crossref","first-page":"409","DOI":"10.1016\/j.jcpa.2017.03.004","article-title":"Vaccination against louping-ill virus protects goats from experimental challenge with Spanish goat encephalitis virus","volume":"156","author":"Salinas","year":"2017","journal-title":"Journal of Comparative Pathology"},{"key":"10.1016\/j.jcpa.2017.09.002_bib29","doi-asserted-by":"crossref","first-page":"137","DOI":"10.1053\/jcpa.2001.0533","article-title":"The pathogenicity of louping-ill virus for mice and lambs","volume":"126","author":"Sheahan","year":"2002","journal-title":"Journal of Comparative Pathology"}],"container-title":["Journal of Comparative Pathology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0021997517303353?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0021997517303353?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,9,19]],"date-time":"2025-09-19T09:31:52Z","timestamp":1758274312000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0021997517303353"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2017,11]]},"references-count":29,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2017,11]]}},"alternative-id":["S0021997517303353"],"URL":"https:\/\/doi.org\/10.1016\/j.jcpa.2017.09.002","relation":{},"ISSN":["0021-9975"],"issn-type":[{"value":"0021-9975","type":"print"}],"subject":[],"published":{"date-parts":[[2017,11]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"120 years of Louping-ill Research: an Historical Perspective from the Archive of the Journal of Comparative Pathology","name":"articletitle","label":"Article Title"},{"value":"Journal of Comparative Pathology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.jcpa.2017.09.002","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"simple-article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2017 Elsevier Ltd. All rights reserved.","name":"copyright","label":"Copyright"}]}}