{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,10]],"date-time":"2026-10-10T21:20:50Z","timestamp":1791667250542,"version":"4.3.4"},"reference-count":20,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2026,8,1]],"date-time":"2026-08-01T00:00:00Z","timestamp":1785542400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2026,8,1]],"date-time":"2026-08-01T00:00:00Z","timestamp":1785542400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2026,8,1]],"date-time":"2026-08-01T00:00:00Z","timestamp":1785542400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2026,8,1]],"date-time":"2026-08-01T00:00:00Z","timestamp":1785542400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2026,8,1]],"date-time":"2026-08-01T00:00:00Z","timestamp":1785542400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2026,8,1]],"date-time":"2026-08-01T00:00:00Z","timestamp":1785542400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2026,8,1]],"date-time":"2026-08-01T00:00:00Z","timestamp":1785542400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"funder":[{"DOI":"10.13039\/501100001691","name":"Japan Society for the Promotion of Science","doi-asserted-by":"publisher","award":["23H02380"],"award-info":[{"award-number":["23H02380"]}],"id":[{"id":"10.13039\/501100001691","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Journal of Comparative Pathology"],"published-print":{"date-parts":[[2026,8]]},"DOI":"10.1016\/j.jcpa.2026.07.003","type":"journal-article","created":{"date-parts":[[2026,8,3]],"date-time":"2026-08-03T07:23:02Z","timestamp":1785741782000},"page":"14-18","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":1,"special_numbering":"C","title":["Triple amyloidosis involving fibrinogen A\u03b1-chain, apolipoprotein A-I and EGF-containing fibulin-like matrix protein 1 in an aged dog"],"prefix":"10.1016","volume":"229","author":[{"ORCID":"https:\/\/orcid.org\/0009-0005-0601-9137","authenticated-orcid":false,"given":"Susumu","family":"Iwaide","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0005-0369-9210","authenticated-orcid":false,"given":"Mitsuhiro","family":"Ikeda","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ryo","family":"Tsuboi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Natsumi","family":"Kobayashi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yoshiyuki","family":"Itoh","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Momoko","family":"Yoshikura","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6650-0417","authenticated-orcid":false,"given":"Hirotaka","family":"Kondo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5706-7842","authenticated-orcid":false,"given":"Tomoaki","family":"Murakami","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.jcpa.2026.07.003_bib1","doi-asserted-by":"crossref","first-page":"249","DOI":"10.1080\/13506129.2024.2405948","article-title":"Amyloid nomenclature 2024: update, novel proteins, and recommendations by the International Society of Amyloidosis (ISA) nomenclature committee","volume":"31","author":"Buxbaum","year":"2024","journal-title":"Amyloid"},{"key":"10.1016\/j.jcpa.2026.07.003_bib2","doi-asserted-by":"crossref","first-page":"117","DOI":"10.1177\/03009858241283750","article-title":"Classification of amyloidosis and protein misfolding disorders in animals 2024: a review on pathology and diagnosis","volume":"62","author":"Iwaide","year":"2025","journal-title":"Vet Pathol"},{"key":"10.1016\/j.jcpa.2026.07.003_bib3","doi-asserted-by":"crossref","first-page":"689","DOI":"10.1177\/10406387251331933","article-title":"Identification of fibrinogen A\u03b1-chain as an amyloid precursor protein in a case of canine coronary artery amyloidosis","volume":"37","author":"Iwaide","year":"2025","journal-title":"J Vet Diagn Invest"},{"key":"10.1016\/j.jcpa.2026.07.003_bib4","doi-asserted-by":"crossref","DOI":"10.1016\/j.arr.2021.101388","article-title":"Age-related amyloidosis outside the brain: a state-of-the-art review","volume":"70","author":"Tasaki","year":"2021","journal-title":"Ageing Res Rev"},{"key":"10.1016\/j.jcpa.2026.07.003_bib5","doi-asserted-by":"crossref","first-page":"26","DOI":"10.1016\/j.jcpa.2025.07.009","article-title":"Epidermal growth factor-containing fibulin-like extracellular matrix 1-derived amyloidosis with fatal gastric bleeding in a Tsushima leopard cat (Prionailurus bengalensis euptilurus)","volume":"221","author":"Fukui","year":"2025","journal-title":"J Comp Pathol"},{"key":"10.1016\/j.jcpa.2026.07.003_bib6","doi-asserted-by":"crossref","first-page":"152","DOI":"10.1177\/03009858211048650","article-title":"Systemic amyloidosis derived from EFEMP1 in a captive Tsushima leopard cat","volume":"59","author":"Miyazaki","year":"2022","journal-title":"Vet Pathol"},{"key":"10.1016\/j.jcpa.2026.07.003_bib7","doi-asserted-by":"crossref","first-page":"84","DOI":"10.1080\/13506129.2024.2421434","article-title":"Identification of epidermal growth factor-containing fibulin-like extracellular matrix protein 1-derived amyloid deposition in a rhesus macaque","volume":"32","author":"Starost","year":"2025","journal-title":"Amyloid"},{"key":"10.1016\/j.jcpa.2026.07.003_bib8","doi-asserted-by":"crossref","first-page":"444","DOI":"10.1002\/path.5203","article-title":"A novel age\u2010related venous amyloidosis derived from EGF\u2010containing fibulin\u2010like extracellular matrix protein 1","volume":"247","author":"Tasaki","year":"2019","journal-title":"J Pathol"},{"key":"10.1016\/j.jcpa.2026.07.003_bib9","doi-asserted-by":"crossref","DOI":"10.1016\/j.humpath.2025.105954","article-title":"Dual amyloidosis: a clinicopathologic and proteomic analysis of 111 patients","volume":"166","author":"Dalland","year":"2025","journal-title":"Human Pathol"},{"key":"10.1016\/j.jcpa.2026.07.003_bib10","doi-asserted-by":"crossref","DOI":"10.3389\/fvets.2023.1082102","article-title":"Life expectancy tables for dogs and cats derived from clinical data","volume":"10","author":"Montoya","year":"2023","journal-title":"Front Vet Sci"},{"key":"10.1016\/j.jcpa.2026.07.003_bib11","doi-asserted-by":"crossref","first-page":"1","DOI":"10.2460\/javma.24.01.0068","article-title":"How can we achieve more accurate reporting of average dog lifespan?","volume":"262","author":"Sexton","year":"2024","journal-title":"J Am Vet Med Assoc"},{"key":"10.1016\/j.jcpa.2026.07.003_bib12","doi-asserted-by":"crossref","first-page":"235","DOI":"10.1080\/13506129.2026.2637775","article-title":"Systemic fibrinogen A\u03b1-chain amyloidosis in Manchester terrier dogs","volume":"33","author":"Kobayashi","year":"2026","journal-title":"Amyloid"},{"key":"10.1016\/j.jcpa.2026.07.003_bib13","first-page":"1311","article-title":"Apolipoprotein Al-derived pulmonary vascular amyloid in aged dogs","volume":"147","author":"Roertgen","year":"1995","journal-title":"Am J Pathol"},{"key":"10.1016\/j.jcpa.2026.07.003_bib14","doi-asserted-by":"crossref","first-page":"96","DOI":"10.1002\/path.6150","article-title":"Fibrinogen A\u03b1\u2010chain amyloidosis outbreaks in Japanese squirrels (Sciurus lis): a potential disease model","volume":"261","author":"Iwaide","year":"2023","journal-title":"J Pathol"},{"key":"10.1016\/j.jcpa.2026.07.003_bib15","doi-asserted-by":"crossref","first-page":"67","DOI":"10.1354\/vp.45-1-67","article-title":"Transthyretin amyloidosis and two other aging-related amyloidoses in an aged vervet monkey","volume":"45","author":"Nakamura","year":"2008","journal-title":"Vet Pathol"},{"key":"10.1016\/j.jcpa.2026.07.003_bib16","doi-asserted-by":"crossref","first-page":"319","DOI":"10.3390\/ijms23010319","article-title":"Classification of amyloidosis by model-assisted mass spectrometry-based proteomics","volume":"23","author":"Palstr\u00f8m","year":"2021","journal-title":"Int J Mol Sci"},{"key":"10.1016\/j.jcpa.2026.07.003_bib17","doi-asserted-by":"crossref","first-page":"218","DOI":"10.1538\/expanim.22-0125","article-title":"Local administration of amyloid enhancing factor initiates in situ amyloid A deposition followed by systemic lesions in mice","volume":"72","author":"Iwaide","year":"2023","journal-title":"Exp Anim"},{"key":"10.1016\/j.jcpa.2026.07.003_bib18","doi-asserted-by":"crossref","first-page":"320","DOI":"10.3390\/ijms19010320","article-title":"Hereditary fibrinogen A\u03b1-chain amyloidosis in Asia: clinical and molecular characteristics","volume":"19","author":"Yazaki","year":"2018","journal-title":"Int J Mol Sci"},{"key":"10.1016\/j.jcpa.2026.07.003_bib19","doi-asserted-by":"crossref","first-page":"94","DOI":"10.1177\/019262338901700105","article-title":"Spontaneous and induced arterial disease in the dog: pathology and pathogenesis","volume":"17","author":"Detweiler","year":"1989","journal-title":"Toxicol Pathol"},{"key":"10.1016\/j.jcpa.2026.07.003_bib20","doi-asserted-by":"crossref","first-page":"222","DOI":"10.1111\/vde.13316","article-title":"Localised apolipoprotein A\u2010I amyloidosis arising in a fibroadnexal hamartoma in a dog","volume":"36","author":"Murakami","year":"2025","journal-title":"Vet Dermatol"}],"container-title":["Journal of Comparative Pathology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0021997526001003?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0021997526001003?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,8,7]],"date-time":"2026-08-07T06:14:15Z","timestamp":1786083255000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0021997526001003"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,8]]},"references-count":20,"alternative-id":["S0021997526001003"],"URL":"https:\/\/doi.org\/10.1016\/j.jcpa.2026.07.003","relation":{},"ISSN":["0021-9975"],"issn-type":[{"value":"0021-9975","type":"print"}],"subject":[],"published":{"date-parts":[[2026,8]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Triple amyloidosis involving fibrinogen A\u03b1-chain, apolipoprotein A-I and EGF-containing fibulin-like matrix protein 1 in an aged dog","name":"articletitle","label":"Article Title"},{"value":"Journal of Comparative Pathology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.jcpa.2026.07.003","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2026 Elsevier Ltd. All rights are reserved, including those for text and data mining, AI training, and similar technologies.","name":"copyright","label":"Copyright"}]}}