{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,2]],"date-time":"2026-07-02T21:21:42Z","timestamp":1783027302674,"version":"3.54.6"},"reference-count":38,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2026,6,1]],"date-time":"2026-06-01T00:00:00Z","timestamp":1780272000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2026,6,1]],"date-time":"2026-06-01T00:00:00Z","timestamp":1780272000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2026,3,29]],"date-time":"2026-03-29T00:00:00Z","timestamp":1774742400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100000272","name":"National Institute for Health and Care Research","doi-asserted-by":"publisher","award":["NIHR133 231"],"award-info":[{"award-number":["NIHR133 231"]}],"id":[{"id":"10.13039\/501100000272","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100007112","name":"Universityof CapeTown","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100007112","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Journal of Cancer Policy"],"published-print":{"date-parts":[[2026,6]]},"DOI":"10.1016\/j.jcpo.2026.100725","type":"journal-article","created":{"date-parts":[[2026,3,27]],"date-time":"2026-03-27T04:01:09Z","timestamp":1774584069000},"page":"100725","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":0,"special_numbering":"C","title":["Treatment cost of colon cancer at a South African tertiary academic hospital"],"prefix":"10.1016","volume":"48","author":[{"ORCID":"https:\/\/orcid.org\/0009-0007-9590-0886","authenticated-orcid":false,"given":"Kelechi","family":"Nnene","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0003-0633-8985","authenticated-orcid":false,"given":"Bhavesh","family":"Nagar","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6413-5890","authenticated-orcid":false,"given":"Adam","family":"Boutall","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4409-6660","authenticated-orcid":false,"given":"Claire","family":"Warden","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"John E.","family":"Ataguba","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jennifer","family":"Moodley","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2134-4905","authenticated-orcid":false,"given":"Lucy","family":"Cunnama","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.jcpo.2026.100725_b1","series-title":"Global Cancer Observatory: Cancer Today","author":"Ferlay","year":"2024"},{"issue":"4","key":"10.1016\/j.jcpo.2026.100725_b2","doi-asserted-by":"crossref","first-page":"465","DOI":"10.1001\/jamaoncol.2022.7826","article-title":"Estimates and projections of the global economic cost of 29 cancers in 204 countries and territories from 2020 to 2050","volume":"9","author":"Chen","year":"2023","journal-title":"JAMA Oncol."},{"key":"10.1016\/j.jcpo.2026.100725_b3","series-title":"GBD Compare Data Visualization","author":"Institute for Health Metrics and Evaluation (IHME)","year":"2024"},{"issue":"3","key":"10.1016\/j.jcpo.2026.100725_b4","first-page":"229","article-title":"Global cancer statistics 2022: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries","volume":"74","author":"Bray","year":"2024","journal-title":"CA: Cancer J. Clin."},{"issue":"4","key":"10.1016\/j.jcpo.2026.100725_b5","doi-asserted-by":"crossref","first-page":"510","DOI":"10.1093\/annonc\/mdz044","article-title":"Meeting report from the joint IARC\u2013NCI international cancer seminar series: a focus on colorectal cancer","volume":"30","author":"Gunter","year":"2019","journal-title":"Ann. Oncol."},{"issue":"10","key":"10.1016\/j.jcpo.2026.100725_b6","doi-asserted-by":"crossref","DOI":"10.1016\/j.tranon.2021.101174","article-title":"Global colorectal cancer burden in 2020 and projections to 2040","volume":"14","author":"Xi","year":"2021","journal-title":"Transl. Oncol."},{"issue":"4","key":"10.1016\/j.jcpo.2026.100725_b7","doi-asserted-by":"crossref","first-page":"683","DOI":"10.1136\/gutjnl-2015-310912","article-title":"Global patterns and trends in colorectal cancer incidence and mortality","volume":"66","author":"Arnold","year":"2017","journal-title":"Gut"},{"key":"10.1016\/j.jcpo.2026.100725_b8","series-title":"World Development Indicators | DataBank","author":"World Bank Group","year":"2024"},{"key":"10.1016\/j.jcpo.2026.100725_b9","series-title":"Poverty | Search Results | Statistics South Africa","author":"Stats","year":"2024"},{"issue":"5","key":"10.1016\/j.jcpo.2026.100725_b10","doi-asserted-by":"crossref","first-page":"721","DOI":"10.1007\/s40258-021-00643-7","article-title":"The impact of financing health services on income inequality in an unequal society: the case of South Africa","volume":"19","author":"Ataguba","year":"2021","journal-title":"Appl. Health Econ. Health Policy"},{"issue":"2","key":"10.1016\/j.jcpo.2026.100725_b11","doi-asserted-by":"crossref","first-page":"118","DOI":"10.7196\/SAMJ.2018.v108i2.12338","article-title":"Colorectal cancer in South Africa: An assessment of disease presentation, treatment pathways and 5-year survival","volume":"108","author":"Brand","year":"2018","journal-title":"SAMJ"},{"key":"10.1016\/j.jcpo.2026.100725_b12","doi-asserted-by":"crossref","first-page":"18","DOI":"10.1016\/j.jcpo.2017.11.005","article-title":"Access to colorectal cancer (CRC) chemotherapy and the associated costs in a South African public healthcare patient cohort","volume":"15","author":"lee Herbst","year":"2018","journal-title":"J. Cancer Policy"},{"issue":"7","key":"10.1016\/j.jcpo.2026.100725_b13","doi-asserted-by":"crossref","first-page":"577","DOI":"10.1007\/s40273-013-0055-4","article-title":"Cost of illness in colorectal cancer: an international review","volume":"31","author":"Kriza","year":"2013","journal-title":"Pharmacoeconomics"},{"issue":"10","key":"10.1016\/j.jcpo.2026.100725_b14","doi-asserted-by":"crossref","first-page":"2082","DOI":"10.1016\/j.ejso.2022.06.023","article-title":"Cost of colorectal cancer by treatment type from different health economic perspectives: A systematic review","volume":"48","author":"Bhimani","year":"2022","journal-title":"Ejso"},{"key":"10.1016\/j.jcpo.2026.100725_b15","doi-asserted-by":"crossref","first-page":"97","DOI":"10.1016\/j.puhe.2022.06.022","article-title":"Cost of treating metastatic colorectal cancer: a systematic review","volume":"211","author":"Bhimani","year":"2022","journal-title":"Public Health"},{"issue":"5","key":"10.1016\/j.jcpo.2026.100725_b16","doi-asserted-by":"crossref","first-page":"371","DOI":"10.1016\/j.currproblcancer.2017.05.001","article-title":"Direct medical cost associated with colorectal cancer in north of Jordan","volume":"41","author":"Alefan","year":"2017","journal-title":"Curr. Probl. Cancer"},{"issue":"11","key":"10.1016\/j.jcpo.2026.100725_b17","doi-asserted-by":"crossref","first-page":"1286","DOI":"10.1038\/bjc.2016.77","article-title":"Cost of care for cancer patients in England: evidence from population-based patient-level data","volume":"114","author":"Laudicella","year":"2016","journal-title":"Br. J. Cancer"},{"key":"10.1016\/j.jcpo.2026.100725_b18","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1186\/s12913-020-05112-w","article-title":"Colorectal Cancer (CRC) treatment and associated costs in the public sector compared to the private sector in Johannesburg, South Africa","volume":"20","author":"Herbst","year":"2020","journal-title":"BMC Health Serv. Res."},{"issue":"1","key":"10.1016\/j.jcpo.2026.100725_b19","doi-asserted-by":"crossref","first-page":"23573","DOI":"10.3402\/gha.v7.23573","article-title":"Step-by-step guideline for disease-specific costing studies in low-and middle-income countries: a mixed methodology","volume":"7","author":"Hendriks","year":"2014","journal-title":"Glob. Health Action"},{"key":"10.1016\/j.jcpo.2026.100725_b20","series-title":"Methods for the Economic Evaluation of Health Care Programmes","author":"Drummond","year":"2015"},{"key":"10.1016\/j.jcpo.2026.100725_b21","series-title":"Analysis of Hospital Costs: A Manual for Managers","author":"Shepard","year":"2000"},{"key":"10.1016\/j.jcpo.2026.100725_b22","series-title":"Order of Magnitude Estimator for New Hospitals","author":"Infrastructure Unit Support Systems (IUSS)","year":"2024"},{"key":"10.1016\/j.jcpo.2026.100725_b23","series-title":"CPI headlines","author":"Stats","year":"2024"},{"key":"10.1016\/j.jcpo.2026.100725_b24","series-title":"Appendices A to H to Circular 20 of 2023 [Dataset]","author":"Department of Public Sservice and Administration","year":"2023"},{"key":"10.1016\/j.jcpo.2026.100725_b25","series-title":"Current-Master-Health-Product-List [Dataset]","author":"National Department of Health","year":"2024"},{"key":"10.1016\/j.jcpo.2026.100725_b26","series-title":"Uniform Patient Fee Schedule","author":"Western Cape Health Department","year":"2024"},{"issue":"2","key":"10.1016\/j.jcpo.2026.100725_b27","first-page":"161","article-title":"A comparative cost analysis of two screening strategies for colorectal cancer in Lynch Syndrome in a South African tertiary hospital","volume":"34","author":"Johnson","year":"2023","journal-title":"CCC"},{"key":"10.1016\/j.jcpo.2026.100725_b28","series-title":"Average exchange rates","author":"South African Revenue Services","year":"2024"},{"issue":"3","key":"10.1016\/j.jcpo.2026.100725_b29","doi-asserted-by":"crossref","first-page":"329","DOI":"10.6004\/jnccn.2021.0012","article-title":"Colon cancer, version 2.2021, NCCN clinical practice guidelines in oncology","volume":"19","author":"Benson","year":"2021","journal-title":"J. Natl. Compr. Canc. Netw."},{"issue":"8","key":"10.1016\/j.jcpo.2026.100725_b30","doi-asserted-by":"crossref","first-page":"808","DOI":"10.4251\/wjgo.v12.i8.808","article-title":"Early stage colon cancer: Current treatment standards, evolving paradigms, and future directions","volume":"12","author":"Chakrabarti","year":"2020","journal-title":"World J. Gastrointest. Oncol."},{"issue":"6","key":"10.1016\/j.jcpo.2026.100725_b31","doi-asserted-by":"crossref","DOI":"10.4236\/jct.2012.36145","article-title":"Recent advances in the management of stage IV colon cancer","volume":"3","author":"Kanthan","year":"2012","journal-title":"J. Cancer Ther."},{"issue":"8","key":"10.1016\/j.jcpo.2026.100725_b32","doi-asserted-by":"crossref","first-page":"1386","DOI":"10.1093\/annonc\/mdw235","article-title":"ESMO consensus guidelines for the management of patients with metastatic colorectal cancer","volume":"27","author":"Van Cutsem","year":"2016","journal-title":"Ann. Oncol."},{"issue":"2","key":"10.1016\/j.jcpo.2026.100725_b33","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0088407","article-title":"Estimating colorectal cancer treatment costs: a pragmatic approach exemplified by health insurance data from Germany","volume":"9","author":"Haug","year":"2014","journal-title":"PLoS One"},{"issue":"2","key":"10.1016\/j.jcpo.2026.100725_b34","article-title":"Patterns of African healthcare funding: investment implications for public-private partnerships","volume":"9","author":"Edet-Utan","year":"2021","journal-title":"Texila Int. J. Public Health"},{"key":"10.1016\/j.jcpo.2026.100725_b35","series-title":"WHO Report on Cancer: Setting Priorities, Investing Wisely and Providing Care for All","author":"World Health Organization","year":"2020"},{"key":"10.1016\/j.jcpo.2026.100725_b36","first-page":"1","article-title":"WHO Cancer Resolution; Cancer prevention and control in the context of an integrated approach","volume":"vol. 22","author":"World Health Organization","year":"2017"},{"issue":"9","key":"10.1016\/j.jcpo.2026.100725_b37","first-page":"1887","article-title":"Resource use and costs associated to the initial phase of treatment for patients with colorectal cancer receiving post-surgery chemotherapy: A cost analysis from a healthcare perspective","volume":"50","author":"Nejati","year":"2021","journal-title":"Iran. J. Publ. Health"},{"key":"10.1016\/j.jcpo.2026.100725_b38","first-page":"2023","article-title":"Improving perioperative cancer care: experience with the Enhanced Recovery After Surgery (ERAS) programme","volume":"26","author":"Oodit","year":"2024","journal-title":"South Afr. Health Rev."}],"container-title":["Journal of Cancer Policy"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2213538326000251?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2213538326000251?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,7,2]],"date-time":"2026-07-02T20:49:55Z","timestamp":1783025395000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S2213538326000251"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,6]]},"references-count":38,"alternative-id":["S2213538326000251"],"URL":"https:\/\/doi.org\/10.1016\/j.jcpo.2026.100725","relation":{},"ISSN":["2213-5383"],"issn-type":[{"value":"2213-5383","type":"print"}],"subject":[],"published":{"date-parts":[[2026,6]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Treatment cost of colon cancer at a South African tertiary academic hospital","name":"articletitle","label":"Article Title"},{"value":"Journal of Cancer Policy","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.jcpo.2026.100725","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2026 The Authors. Published by Elsevier Ltd.","name":"copyright","label":"Copyright"}],"article-number":"100725"}}