{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,1]],"date-time":"2026-10-01T22:04:10Z","timestamp":1790892250516,"version":"4.1.0"},"reference-count":26,"publisher":"Elsevier BV","issue":"4","license":[{"start":{"date-parts":[[2010,12,1]],"date-time":"2010-12-01T00:00:00Z","timestamp":1291161600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Journal of Critical Care"],"published-print":{"date-parts":[[2010,12]]},"DOI":"10.1016\/j.jcrc.2010.03.002","type":"journal-article","created":{"date-parts":[[2010,5,3]],"date-time":"2010-05-03T06:29:22Z","timestamp":1272868162000},"page":"570-575","source":"Crossref","is-referenced-by-count":74,"title":["Eosinopenia: Is it a good marker of sepsis in comparison to procalcitonin and C-reactive protein levels for patients admitted to a critical care unit in an urban hospital?"],"prefix":"10.1016","volume":"25","author":[{"given":"Hamid","family":"Shaaban","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sunil","family":"Daniel","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Raymond","family":"Sison","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jihad","family":"Slim","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"George","family":"Perez","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.jcrc.2010.03.002_bib1","doi-asserted-by":"crossref","first-page":"465","DOI":"10.1097\/00075198-200210000-00016","article-title":"New concepts in sepsis","volume":"8","author":"Curtis","year":"2002","journal-title":"Curr Opin Crit Care"},{"key":"10.1016\/j.jcrc.2010.03.002_bib2","doi-asserted-by":"crossref","first-page":"1644","DOI":"10.1378\/chest.101.6.1644","article-title":"American College of Chest Physicians\/Society of Critical Care Medicine Consensus Conference: definition for sepsis and organ failure and guidelines for the use of innovative therapies in sepsis","volume":"101","author":"Bone","year":"1992","journal-title":"Chest"},{"key":"10.1016\/j.jcrc.2010.03.002_bib3","series-title":"A Manual of Clinical Diagnosis","first-page":"53","author":"Simon","year":"1922"},{"key":"10.1016\/j.jcrc.2010.03.002_bib4","doi-asserted-by":"crossref","first-page":"R59","DOI":"10.1186\/cc6883","article-title":"Eosinopenia is a reliable marker of sepsis on admission to medical intensive care units","volume":"12","author":"Abidi","year":"2008","journal-title":"Crit Care"},{"key":"10.1016\/j.jcrc.2010.03.002_bib5","doi-asserted-by":"crossref","first-page":"477","DOI":"10.1007\/s00134-006-0509-7","article-title":"Procalcitonin and C-reactive protein as markers of systemic inflammatory response syndrome severity in critically ill children","volume":"33","author":"Rey","year":"2007","journal-title":"Intensive Care Med"},{"key":"10.1016\/j.jcrc.2010.03.002_bib6","doi-asserted-by":"crossref","first-page":"1737","DOI":"10.1097\/01.CCM.0000063440.19188.ED","article-title":"Comparison of procalcitonin and C-reactive protein as markers of sepsis","volume":"31","author":"Luzzani","year":"2003","journal-title":"Crit Care Med"},{"key":"10.1016\/j.jcrc.2010.03.002_bib7","doi-asserted-by":"crossref","first-page":"2172","DOI":"10.1097\/00003246-199910000-00016","article-title":"Discrimination of infectious and non infectious causes of early acute respiratory distress syndrome by procalcitonin","volume":"27","author":"Brunkhorst","year":"1999","journal-title":"Crit Care Med"},{"key":"10.1016\/j.jcrc.2010.03.002_bib8","doi-asserted-by":"crossref","first-page":"3171","DOI":"10.1097\/00003246-200009000-00008","article-title":"Usefulness of procalcitonin for diagnosis of infection in cardiac surgical patients","volume":"28","author":"Aouifi","year":"2000","journal-title":"Crit Care Med"},{"key":"10.1016\/j.jcrc.2010.03.002_bib9","doi-asserted-by":"crossref","first-page":"95","DOI":"10.1186\/cc469","article-title":"Procalcitonin for early diagnosis and differentiation of SIRS, sepsis, severe sepsis and septic shock","volume":"3","author":"Brunkhorst","year":"1999","journal-title":"Crit Care"},{"key":"10.1016\/j.jcrc.2010.03.002_bib10","doi-asserted-by":"crossref","first-page":"977","DOI":"10.1097\/00003246-200004000-00011","article-title":"Calcitonin precursors are reliable markers of sepsis in a medical intensive care unit","volume":"28","author":"Muller","year":"2000","journal-title":"Crit Care Med"},{"key":"10.1016\/j.jcrc.2010.03.002_bib11","doi-asserted-by":"crossref","first-page":"1193","DOI":"10.1007\/s001340000624","article-title":"Procalcitonin as a marker of the systemic inflammatory response to infection","volume":"26","author":"Reinhart","year":"2000","journal-title":"Intensive Care Med"},{"key":"10.1016\/j.jcrc.2010.03.002_bib12","doi-asserted-by":"crossref","first-page":"396","DOI":"10.1164\/ajrccm.164.3.2009052","article-title":"Geneva Sepsis Network: diagnosis value of procalcitonin, interleukin-6 and interleukin-8 in critically ill patients admitted with suspected sepsis","volume":"3","author":"Harbarth","year":"2001","journal-title":"Am J Respir Crit Care Med"},{"key":"10.1016\/j.jcrc.2010.03.002_bib13","doi-asserted-by":"crossref","first-page":"85","DOI":"10.1186\/cc1843","article-title":"Usefulness of procalcitonin for diagnosis of sepsis in intensive care unit","volume":"7","author":"BalcI","year":"2003","journal-title":"Crit Care"},{"key":"10.1016\/j.jcrc.2010.03.002_bib14","doi-asserted-by":"crossref","first-page":"600","DOI":"10.1016\/S0140-6736(04)15591-8","article-title":"Effect of procalcitonin-guided treatment on antibiotic use and outcome in lower respiratory tract infections: cluster-randomised, single-blinded intervention trial","volume":"363","author":"Christ-Crain","year":"2004","journal-title":"Lancet"},{"key":"10.1016\/j.jcrc.2010.03.002_bib15","doi-asserted-by":"crossref","first-page":"9","DOI":"10.7326\/0003-4819-141-1-200407060-00009","article-title":"Plasma level of a triggering receptor expressed on myeloid cells-1: its diagnostic accuracy in patients with suspected sepsis","volume":"141","author":"Gibot","year":"2004","journal-title":"Ann Intern Med"},{"key":"10.1016\/j.jcrc.2010.03.002_bib16","doi-asserted-by":"crossref","first-page":"1265","DOI":"10.1172\/JCI109789","article-title":"Eosinopenia of acute infection: production of eosinopenia by chemotactic factors of acute inflammation","volume":"65","author":"Bass","year":"1980","journal-title":"J Clin Invest"},{"key":"10.1016\/j.jcrc.2010.03.002_bib17","first-page":"227","article-title":"Ueber das Vorkommen der Eosinophilen Zellen in menschlichen Blute","volume":"23","author":"Zappert","year":"1893","journal-title":"Z Klin Med"},{"key":"10.1016\/j.jcrc.2010.03.002_bib18","first-page":"397","article-title":"The blood picture during the alarm reaction","volume":"62","author":"Dalton","year":"1939","journal-title":"Folia Haematol"},{"key":"10.1016\/j.jcrc.2010.03.002_bib19","series-title":"The Eosinophils in Physiology and Pathology of the Leukocytes","first-page":"1","author":"Gross","year":"1962"},{"key":"10.1016\/j.jcrc.2010.03.002_bib20","doi-asserted-by":"crossref","first-page":"431","DOI":"10.1016\/S0248-8663(03)00138-3","article-title":"Value of eosinopenia in inflammatory disorders: an 'old' marker revisited","volume":"24","author":"Gil","year":"2003","journal-title":"Rev Med Interne"},{"key":"10.1016\/j.jcrc.2010.03.002_bib21","series-title":"Intensive care medicine","author":"Irwin and Rippe","year":"2008"},{"key":"10.1016\/j.jcrc.2010.03.002_bib22","doi-asserted-by":"crossref","first-page":"1138","DOI":"10.1016\/j.clinbiochem.2006.08.011","article-title":"Procalcitonin in the diagnosis of inflammation in intensive care units","volume":"39","author":"Dorizzi","year":"2006","journal-title":"Clin Biochem"},{"key":"10.1016\/j.jcrc.2010.03.002_bib23","doi-asserted-by":"crossref","first-page":"R234","DOI":"10.1186\/cc2877","article-title":"Procalcitonin and C-reactive protein during systemic inflammatory response syndrome, sepsis and organ dysfunction","volume":"8","author":"Castelli","year":"2004","journal-title":"Crit Care"},{"key":"10.1016\/j.jcrc.2010.03.002_bib24","doi-asserted-by":"crossref","first-page":"1232","DOI":"10.1007\/s001340000580","article-title":"Procalcitonin: a valuable indicator of infection in a medical ICU?","volume":"26","author":"Suprin","year":"2000","journal-title":"Intensive Care Med"},{"key":"10.1016\/j.jcrc.2010.03.002_bib25","doi-asserted-by":"crossref","first-page":"1592","DOI":"10.1056\/NEJM199805283382206","article-title":"Eosinophilia","volume":"338","author":"Rothenberg","year":"1998","journal-title":"N Engl J Med"},{"key":"10.1016\/j.jcrc.2010.03.002_bib26","doi-asserted-by":"crossref","first-page":"344","DOI":"10.1097\/01.CCM.0000194725.48928.3A","article-title":"Sepsis Occurrence in Acutely Ill Patients Investigators: Sepsis in European intensive care units: results of the SOAP study","volume":"34","author":"Vincent","year":"2006","journal-title":"Crit Care Med"}],"container-title":["Journal of Critical Care"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0883944110000730?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0883944110000730?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2018,12,11]],"date-time":"2018-12-11T11:22:16Z","timestamp":1544527336000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0883944110000730"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2010,12]]},"references-count":26,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2010,12]]}},"alternative-id":["S0883944110000730"],"URL":"https:\/\/doi.org\/10.1016\/j.jcrc.2010.03.002","relation":{},"ISSN":["0883-9441"],"issn-type":[{"value":"0883-9441","type":"print"}],"subject":[],"published":{"date-parts":[[2010,12]]}}}