{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,8]],"date-time":"2026-10-08T14:24:58Z","timestamp":1791469498216,"version":"4.3.4"},"reference-count":22,"publisher":"Elsevier BV","issue":"1","license":[{"start":{"date-parts":[[2016,2,1]],"date-time":"2016-02-01T00:00:00Z","timestamp":1454284800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2016,2,1]],"date-time":"2016-02-01T00:00:00Z","timestamp":1454284800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Journal of Critical Care"],"published-print":{"date-parts":[[2016,2]]},"DOI":"10.1016\/j.jcrc.2015.09.025","type":"journal-article","created":{"date-parts":[[2015,10,8]],"date-time":"2015-10-08T09:39:27Z","timestamp":1444297167000},"page":"243-248","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":31,"title":["Prognosis of patients presenting extreme acidosis (pH &lt; 7) on admission to intensive care unit"],"prefix":"10.1016","volume":"31","author":[{"given":"J\u00e9r\u00f4me","family":"Allyn","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"David","family":"Vandroux","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Julien","family":"Jabot","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Caroline","family":"Brulliard","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Richard","family":"Galliot","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xavier","family":"Tabatchnik","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Patrice","family":"Combe","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Olivier","family":"Martinet","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nicolas","family":"Allou","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.jcrc.2015.09.025_bb0005","doi-asserted-by":"crossref","first-page":"375","DOI":"10.1038\/ki.1972.48","article-title":"The effects of acid-base disturbances on cardiovascular and pulmonary function","volume":"1","author":"Mitchell","year":"1972","journal-title":"Kidney Int"},{"key":"10.1016\/j.jcrc.2015.09.025_bb0010","doi-asserted-by":"crossref","first-page":"331","DOI":"10.1186\/cc2900","article-title":"Science review: extracellular acidosis and the immune response: clinical and physiologic implications","volume":"8","author":"Kellum","year":"2004","journal-title":"Crit Care"},{"key":"10.1016\/j.jcrc.2015.09.025_bb0015","doi-asserted-by":"crossref","first-page":"111","DOI":"10.1007\/s10157-006-0408-9","article-title":"Use of base in the treatment of acute severe organic acidosis by nephrologists and critical care physicians: results of an online survey","volume":"10","author":"Kraut","year":"2006","journal-title":"Clin Exp Nephrol"},{"key":"10.1016\/j.jcrc.2015.09.025_bb0020","doi-asserted-by":"crossref","first-page":"1352","DOI":"10.1097\/00003246-199111000-00008","article-title":"Effects of bicarbonate therapy on hemodynamics and tissue oxygenation in patients with lactic acidosis: a prospective, controlled clinical study","volume":"19","author":"Mathieu","year":"1991","journal-title":"Crit Care Med"},{"key":"10.1016\/j.jcrc.2015.09.025_bb0025","doi-asserted-by":"crossref","first-page":"970","DOI":"10.1345\/aph.1S014","article-title":"Intravenous sodium bicarbonate therapy in severely acidotic diabetic ketoacidosis","volume":"47","author":"Duhon","year":"2013","journal-title":"Ann Pharmacother"},{"key":"10.1016\/j.jcrc.2015.09.025_bb0030","doi-asserted-by":"crossref","first-page":"2191","DOI":"10.1097\/CCM.0b013e3181a02490","article-title":"Metformin-associated lactic acidosis: a prognostic and therapeutic study","volume":"37","author":"Seidowsky","year":"2009","journal-title":"Crit Care Med"},{"key":"10.1016\/j.jcrc.2015.09.025_bb0035","doi-asserted-by":"crossref","first-page":"1120","DOI":"10.1097\/01.CCM.0000125517.28517.74","article-title":"Initial pH, base deficit, lactate, anion gap, strong ion difference, and strong ion gap predict outcome from major vascular injury","volume":"32","author":"Kaplan","year":"2004","journal-title":"Crit Care Med"},{"key":"10.1016\/j.jcrc.2015.09.025_bb0040","doi-asserted-by":"crossref","first-page":"1804","DOI":"10.1097\/CCM.0000000000000332","article-title":"Initial lactate and lactate change in post\u2013cardiac arrest: a multicenter validation study","volume":"42","author":"Donnino","year":"2014","journal-title":"Crit Care Med"},{"key":"10.1016\/j.jcrc.2015.09.025_bb0045","doi-asserted-by":"crossref","first-page":"2009","DOI":"10.1097\/CCM.0b013e31824e9eae","article-title":"Variation in use of intensive care for adults with diabetic ketoacidosis*","volume":"40","author":"Gershengorn","year":"2012","journal-title":"Crit Care Med"},{"key":"10.1016\/j.jcrc.2015.09.025_bb0050","doi-asserted-by":"crossref","first-page":"2733","DOI":"10.1097\/CCM.0b013e3181a59165","article-title":"Metabolic acidosis in patients with severe sepsis and septic shock: a longitudinal quantitative study","volume":"37","author":"Noritomi","year":"2009","journal-title":"Crit Care Med"},{"key":"10.1016\/j.jcrc.2015.09.025_bb0055","doi-asserted-by":"crossref","first-page":"74","DOI":"10.1007\/s001340051352","article-title":"Base excess and lactate as prognostic indicators for patients admitted to intensive care","volume":"27","author":"Smith","year":"2001","journal-title":"Intensive Care Med"},{"key":"10.1016\/j.jcrc.2015.09.025_bb0060","doi-asserted-by":"crossref","first-page":"12","DOI":"10.1186\/2110-5820-3-12","article-title":"Clinical use of lactate monitoring in critically ill patients","volume":"3","author":"Bakker","year":"2013","journal-title":"Ann Intensive Care"},{"key":"10.1016\/j.jcrc.2015.09.025_bb0065","doi-asserted-by":"crossref","first-page":"R226","DOI":"10.1186\/cc9376","article-title":"Outcome of severe lactic acidosis associated with metformin accumulation","volume":"14","author":"Friesecke","year":"2010","journal-title":"Crit Care"},{"key":"10.1016\/j.jcrc.2015.09.025_bb0070","doi-asserted-by":"crossref","first-page":"210","DOI":"10.1016\/j.jcrc.2013.11.007","article-title":"Severe acidosis does not predict fatal outcomes in intensive care unit patients: a retrospective analysis","volume":"29","author":"Paz","year":"2014","journal-title":"J Crit Care"},{"key":"10.1016\/j.jcrc.2015.09.025_bb0075","series-title":"vol. Deuxieme edition francaise","article-title":"Pr\u00e9cis de physiologie m\u00e9dicale","author":"Guyton","year":"2003"},{"key":"10.1016\/j.jcrc.2015.09.025_bb0080","doi-asserted-by":"crossref","first-page":"181","DOI":"10.2337\/diab.32.2.181","article-title":"Lactic acidosis revisited","volume":"32","author":"Cohen","year":"1983","journal-title":"Diabetes"},{"key":"10.1016\/j.jcrc.2015.09.025_bb0085","doi-asserted-by":"crossref","first-page":"2957","DOI":"10.1001\/jama.1993.03510240069035","article-title":"A new Simplified Acute Physiology Score (SAPS II) based on a European\/North American multicenter study","volume":"270","author":"Le Gall","year":"1993","journal-title":"JAMA"},{"key":"10.1016\/j.jcrc.2015.09.025_bb0090","doi-asserted-by":"crossref","first-page":"175","DOI":"10.1186\/s13054-015-0896-7","article-title":"Hemodynamic consequences of severe lactic acidosis in shock states: from bench to bedside","volume":"19","author":"Kimmoun","year":"2015","journal-title":"Crit Care"},{"key":"10.1016\/j.jcrc.2015.09.025_bb0095","doi-asserted-by":"crossref","first-page":"1444","DOI":"10.1139\/y83-207","article-title":"Modern quantitative acid-base chemistry","volume":"61","author":"Stewart","year":"1983","journal-title":"Can J Physiol Pharmacol"},{"key":"10.1016\/j.jcrc.2015.09.025_bb0100","doi-asserted-by":"crossref","first-page":"R22","DOI":"10.1186\/cc3987","article-title":"Lactate versus non-lactate metabolic acidosis: a retrospective outcome evaluation of critically ill patients","volume":"10","author":"Gunnerson","year":"2006","journal-title":"Crit Care"},{"key":"10.1016\/j.jcrc.2015.09.025_bb0105","doi-asserted-by":"crossref","first-page":"R41","DOI":"10.1186\/cc2184","article-title":"Conventional or physicochemical approach in intensive care unit patients with metabolic acidosis","volume":"7","author":"Moviat","year":"2003","journal-title":"Crit Care"},{"key":"10.1016\/j.jcrc.2015.09.025_bb0110","doi-asserted-by":"crossref","first-page":"1227","DOI":"10.1097\/01.CCM.0000125513.26170.D2","article-title":"Assessing metabolic acidosis in the intensive care unit: does the method make a difference?","volume":"32","author":"Carreira","year":"2004","journal-title":"Crit Care Med"}],"container-title":["Journal of Critical Care"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0883944115005067?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0883944115005067?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,10]],"date-time":"2025-10-10T19:39:28Z","timestamp":1760125168000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0883944115005067"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2016,2]]},"references-count":22,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2016,2]]}},"alternative-id":["S0883944115005067"],"URL":"https:\/\/doi.org\/10.1016\/j.jcrc.2015.09.025","relation":{},"ISSN":["0883-9441"],"issn-type":[{"value":"0883-9441","type":"print"}],"subject":[],"published":{"date-parts":[[2016,2]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Prognosis of patients presenting extreme acidosis (pH <7) on admission to intensive care unit","name":"articletitle","label":"Article Title"},{"value":"Journal of Critical Care","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.jcrc.2015.09.025","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2015 Elsevier Inc. All rights reserved.","name":"copyright","label":"Copyright"}]}}