{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,11]],"date-time":"2025-11-11T13:25:39Z","timestamp":1762867539155,"version":"build-2065373602"},"reference-count":26,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2018,12,1]],"date-time":"2018-12-01T00:00:00Z","timestamp":1543622400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2018,12,1]],"date-time":"2018-12-01T00:00:00Z","timestamp":1543622400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Journal of Critical Care"],"published-print":{"date-parts":[[2018,12]]},"DOI":"10.1016\/j.jcrc.2018.08.029","type":"journal-article","created":{"date-parts":[[2018,8,24]],"date-time":"2018-08-24T03:11:50Z","timestamp":1535080310000},"page":"130-134","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":3,"special_numbering":"C","title":["Histologically proven acute tubular necrosis in a series of 27 ICU patients"],"prefix":"10.1016","volume":"48","author":[{"given":"Ren\u00e9","family":"Robert","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1230-715X","authenticated-orcid":false,"given":"Denis","family":"Frasca","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Bertrand","family":"Souweine","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1498-2132","authenticated-orcid":false,"given":"Jean-Fran\u00e7ois","family":"Augusto","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Carole","family":"Philipponnet","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Florent","family":"Joly","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jean-Michel","family":"Goujon","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nicolas","family":"Lerolle","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.jcrc.2018.08.029_bb0005","doi-asserted-by":"crossref","first-page":"811","DOI":"10.1038\/ki.1996.380","article-title":"Epidemiology of acute renal failure: A prospective, multicenter, community-based study","volume":"50","author":"Liano","year":"1996","journal-title":"Kidney Int"},{"key":"10.1016\/j.jcrc.2018.08.029_bb0010","doi-asserted-by":"crossref","first-page":"1089","DOI":"10.1038\/ki.2009.332","article-title":"Outcomes following diagnosis of acute renal failure in U.S. veterans: Focus on acute tubular necrosis","volume":"76","author":"Amdur","year":"2009","journal-title":"Kidney Int"},{"key":"10.1016\/j.jcrc.2018.08.029_bb0015","first-page":"1","article-title":"KDIGO clinical practice guideline for acute kidney injury","volume":"2","author":"The Kidney Disease Improving Global Outcomes (KDIGO) Working Group","year":"2012","journal-title":"Kidney Int Suppl"},{"key":"10.1016\/j.jcrc.2018.08.029_bb0020","doi-asserted-by":"crossref","first-page":"1220","DOI":"10.1046\/j.1523-1755.2001.00930.x","article-title":"Difficulties in understanding human \u201cacute tubular necrosis\u201d: Limited data and flawed animal models","volume":"60","author":"Rosen","year":"2001","journal-title":"Kidney Int"},{"key":"10.1016\/j.jcrc.2018.08.029_bb0025","doi-asserted-by":"crossref","first-page":"9","DOI":"10.1038\/ki.2009.347","article-title":"Experimental ischemia\u2013reperfusion: Biases and myths\u2014The proximal vs. distal hypoxic tubular injury debate revisited","volume":"77","author":"Heyman","year":"2010","journal-title":"Kidney Int"},{"key":"10.1016\/j.jcrc.2018.08.029_bb0030","doi-asserted-by":"crossref","first-page":"3","DOI":"10.1097\/SHK.0000000000000052","article-title":"A unified theory of sepsis-induced acute kidney injury: Inflammation, microcirculatory dysfunction, bioenergetics and the tubular cell adaptation injury","volume":"41","author":"Gomez","year":"2014","journal-title":"Shock"},{"key":"10.1016\/j.jcrc.2018.08.029_bb0035","doi-asserted-by":"crossref","first-page":"R363","DOI":"10.1186\/cc3540","article-title":"Renal blood flow in sepsis","volume":"9","author":"Langenberg","year":"2005","journal-title":"Crit Care"},{"key":"10.1016\/j.jcrc.2018.08.029_bb0040","doi-asserted-by":"crossref","first-page":"e58","DOI":"10.1097\/CCM.0b013e3182a639da","article-title":"Renal histopathology during experimental septic acute kidney injury and recovery","volume":"42","author":"Langenberg","year":"2014","journal-title":"Crit Care Med"},{"key":"10.1016\/j.jcrc.2018.08.029_bb0045","doi-asserted-by":"crossref","first-page":"756","DOI":"10.1016\/S0140-6736(11)61454-2","article-title":"Acute kidney injury","volume":"380","author":"Bellomo","year":"2012","journal-title":"Lancet"},{"key":"10.1016\/j.jcrc.2018.08.029_bb0050","first-page":"55","article-title":"Ultrastructural study on kidney cell injury following various types of shock in 26 immediate autopsy patients","volume":"1","author":"Sato","year":"1978","journal-title":"Adv Shock Res"},{"key":"10.1016\/j.jcrc.2018.08.029_bb0055","doi-asserted-by":"crossref","first-page":"1230","DOI":"10.1097\/00003246-199907000-00002","article-title":"Apoptotic cell death in patients with sepsis, shock, and multiple organ dysfunction","volume":"27","author":"Hotchkiss","year":"1999","journal-title":"Crit Care Med"},{"key":"10.1016\/j.jcrc.2018.08.029_bb0060","doi-asserted-by":"crossref","first-page":"471","DOI":"10.1007\/s00134-009-1723-x","article-title":"Histopathology of septic shock induced acute kidney injury: Apoptosis and leukocytic infiltration","volume":"36","author":"Lerolle","year":"2010","journal-title":"Intensive Care Med"},{"key":"10.1016\/j.jcrc.2018.08.029_bb0065","doi-asserted-by":"crossref","first-page":"509","DOI":"10.1164\/rccm.201211-1983OC","article-title":"Mechanisms of cardiac and renal dysfunction in patients dying of sepsis","volume":"187","author":"Takasu","year":"2013","journal-title":"Am J Respir Crit Care Med"},{"key":"10.1016\/j.jcrc.2018.08.029_bb0070","doi-asserted-by":"crossref","first-page":"667","DOI":"10.1080\/08860220802212460","article-title":"Histological features of acute tubular necrosis in native kidneys and long-term renal function","volume":"30","author":"Abdulkader","year":"2008","journal-title":"Ren Fail"},{"key":"10.1016\/j.jcrc.2018.08.029_bb0075","doi-asserted-by":"crossref","first-page":"1826","DOI":"10.1007\/s00134-012-2634-9","article-title":"Safety and diagnostic yield of renal biopsy in the intensive care unit","volume":"38","author":"Augusto","year":"2012","journal-title":"Intensive Care Med"},{"key":"10.1016\/j.jcrc.2018.08.029_bb0080","first-page":"53","article-title":"Kidney biopsy in the critically ill patient, results of a multicentre retrospective case series","volume":"79","author":"Philliponet","year":"2013","journal-title":"Minerva Anestesiol"},{"key":"10.1016\/j.jcrc.2018.08.029_bb0085","doi-asserted-by":"crossref","first-page":"801","DOI":"10.1001\/jama.2016.0287","article-title":"The third international consensus definitions for sepsis and septic shock (Sepsis-3)","volume":"315","author":"Singer","year":"2016","journal-title":"JAMA"},{"key":"10.1016\/j.jcrc.2018.08.029_bb0090","doi-asserted-by":"crossref","first-page":"228","DOI":"10.1006\/jsre.1998.5526","article-title":"Histopathological evaluation of proximal tubule cell injury in isolated perfused pig kidneys exposed to cold ischemia","volume":"82","author":"Goujon","year":"1999","journal-title":"J Surgical Res"},{"key":"10.1016\/j.jcrc.2018.08.029_bb0095","doi-asserted-by":"crossref","first-page":"411","DOI":"10.1038\/ki.1993.259","article-title":"International standardization of criteria for the histologic diagnosis of renal allograft rejection: The Banff working classification of kidney transplant pathology","volume":"44","author":"Solez","year":"1993","journal-title":"Kidney Int"},{"key":"10.1016\/j.jcrc.2018.08.029_bb0100","doi-asserted-by":"crossref","first-page":"27","DOI":"10.1159\/000166768","article-title":"Renal biopsy in acute renal failure","volume":"4","author":"Mustonen","year":"1984","journal-title":"Am J Nephrol"},{"key":"10.1016\/j.jcrc.2018.08.029_bb0105","first-page":"S91","article-title":"Role of renal biopsy in the diagnosis and prognosis of acute renal failure","volume":"66","author":"Andreucci","year":"1998","journal-title":"Kidney Int Suppl"},{"key":"10.1016\/j.jcrc.2018.08.029_bb0110","doi-asserted-by":"crossref","first-page":"480","DOI":"10.1111\/j.1523-1755.2004.761_2.x","article-title":"Ischemic acute renal failure: An inflammatory disease?","volume":"66","author":"Bonventre","year":"2004","journal-title":"Kidney Int"},{"key":"10.1016\/j.jcrc.2018.08.029_bb0115","doi-asserted-by":"crossref","first-page":"797","DOI":"10.1056\/NEJMra064398","article-title":"Normotensive ischemic acute renal failure","volume":"357","author":"Abuelo","year":"2007","journal-title":"N Engl J Med"},{"key":"10.1016\/j.jcrc.2018.08.029_bb0120","doi-asserted-by":"crossref","first-page":"527","DOI":"10.1038\/ki.2009.502","article-title":"Acute kidney injury in non-severe pneumonia is associated with an increased immune response and lower survival","volume":"77","author":"Murugan","year":"2010","journal-title":"Kidney Int"},{"key":"10.1016\/j.jcrc.2018.08.029_bb0125","doi-asserted-by":"crossref","first-page":"R38","DOI":"10.1186\/cc6823","article-title":"The histopathology of septic acute kidney injury: A systematic review","volume":"12","author":"Langenberg","year":"2008","journal-title":"Crit Care"},{"key":"10.1016\/j.jcrc.2018.08.029_bb0130","first-page":"439","article-title":"Severe sepsis as a cause of acute renal failure","volume":"26","author":"Diaz De Leon","year":"2006","journal-title":"Nefrologia"}],"container-title":["Journal of Critical Care"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0883944118308013?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0883944118308013?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,10]],"date-time":"2025-10-10T19:40:04Z","timestamp":1760125204000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0883944118308013"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2018,12]]},"references-count":26,"alternative-id":["S0883944118308013"],"URL":"https:\/\/doi.org\/10.1016\/j.jcrc.2018.08.029","relation":{},"ISSN":["0883-9441"],"issn-type":[{"type":"print","value":"0883-9441"}],"subject":[],"published":{"date-parts":[[2018,12]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Histologically proven acute tubular necrosis in a series of 27 ICU patients","name":"articletitle","label":"Article Title"},{"value":"Journal of Critical Care","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.jcrc.2018.08.029","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2018 Published by Elsevier Inc.","name":"copyright","label":"Copyright"}]}}