{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,17]],"date-time":"2026-06-17T20:57:53Z","timestamp":1781729873145,"version":"3.54.5"},"reference-count":32,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2020,6,1]],"date-time":"2020-06-01T00:00:00Z","timestamp":1590969600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2020,6,1]],"date-time":"2020-06-01T00:00:00Z","timestamp":1590969600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"funder":[{"DOI":"10.13039\/501100003793","name":"Hj\u00e4rt-Lungfonden","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100003793","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100005689","name":"G\u00f6teborgs L\u00e4kares\u00e4llskap","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100005689","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Journal of Critical Care"],"published-print":{"date-parts":[[2020,6]]},"DOI":"10.1016\/j.jcrc.2019.12.022","type":"journal-article","created":{"date-parts":[[2020,1,7]],"date-time":"2020-01-07T04:14:28Z","timestamp":1578370468000},"page":"225-230","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":24,"special_numbering":"C","title":["Effects of milrinone on renal perfusion, filtration and oxygenation in patients with acute heart failure and low cardiac output early after cardiac surgery"],"prefix":"10.1016","volume":"57","author":[{"given":"Lukas","family":"Lannemyr","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gudrun","family":"Bragadottir","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bengt","family":"Redfors","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sven-Erik","family":"Ricksten","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"issue":"1","key":"10.1016\/j.jcrc.2019.12.022_bb0005","doi-asserted-by":"crossref","first-page":"187","DOI":"10.1186\/s13054-016-1352-z","article-title":"Acute kidney injury following cardiac surgery: current understanding and future directions","volume":"20","author":"O\u2019Neal","year":"2016","journal-title":"Crit Care"},{"issue":"2","key":"10.1016\/j.jcrc.2019.12.022_bb0010","doi-asserted-by":"crossref","first-page":"205","DOI":"10.1097\/ALN.0000000000001461","article-title":"Effects of cardiopulmonary bypass on renal perfusion, filtration, and oxygenation in patients undergoing cardiac surgery","volume":"126","author":"Lannemyr","year":"2017","journal-title":"Anesthesiology"},{"issue":"2","key":"10.1016\/j.jcrc.2019.12.022_bb0015","doi-asserted-by":"crossref","first-page":"505","DOI":"10.1016\/j.athoracsur.2018.08.085","article-title":"Impact of cardiopulmonary bypass flow on renal oxygenation in patients undergoing cardiac operations","volume":"107","author":"Lannemyr","year":"2019","journal-title":"Ann Thorac Surg"},{"issue":"9","key":"10.1016\/j.jcrc.2019.12.022_bb0020","doi-asserted-by":"crossref","first-page":"1075","DOI":"10.1111\/aas.12946","article-title":"Renal tubular injury during cardiopulmonary bypass as assessed by urinary release of N-acetyl-ss-D-glucosaminidase","volume":"61","author":"Lannemyr","year":"2017","journal-title":"Acta Anaesthesiol Scand"},{"issue":"7","key":"10.1016\/j.jcrc.2019.12.022_bb0025","doi-asserted-by":"crossref","first-page":"863","DOI":"10.1038\/sj.ki.5002715","article-title":"Urinary biomarkers in the early diagnosis of acute kidney injury","volume":"73","author":"Han","year":"2008","journal-title":"Kidney Int"},{"issue":"5","key":"10.1016\/j.jcrc.2019.12.022_bb0030","doi-asserted-by":"crossref","first-page":"445","DOI":"10.1111\/j.1540-8191.2007.00447.x","article-title":"Impact of off-pump coronary artery bypass surgery on systemic inflammation: current best available evidence","volume":"22","author":"Raja","year":"2007","journal-title":"J Card Surg"},{"issue":"4","key":"10.1016\/j.jcrc.2019.12.022_bb0035","doi-asserted-by":"crossref","first-page":"964","DOI":"10.1097\/ALN.0b013e318210f86a","article-title":"Cardiopulmonary bypass-associated acute kidney injury","volume":"114","author":"Kumar","year":"2011","journal-title":"Anesthesiology"},{"issue":"2","key":"10.1016\/j.jcrc.2019.12.022_bb0040","doi-asserted-by":"crossref","first-page":"201","DOI":"10.1186\/cc8153","article-title":"Clinical review: practical recommendations on the management of perioperative heart failure in cardiac surgery","volume":"14","author":"Mebazaa","year":"2010","journal-title":"Crit Care"},{"issue":"3","key":"10.1016\/j.jcrc.2019.12.022_bb0045","doi-asserted-by":"crossref","first-page":"194","DOI":"10.7326\/0003-4819-128-3-199802010-00005","article-title":"Renal dysfunction after myocardial revascularization: risk factors, adverse outcomes, and hospital resource utilization. The Multicenter Study of Perioperative Ischemia Research Group","volume":"128","author":"Mangano","year":"1998","journal-title":"Ann Intern Med"},{"issue":"1","key":"10.1016\/j.jcrc.2019.12.022_bb0050","doi-asserted-by":"crossref","first-page":"3","DOI":"10.1177\/0885066607309998","article-title":"Cardiac surgery as a cause of acute kidney injury: pathogenesis and potential therapies","volume":"23","author":"Rosner","year":"2008","journal-title":"J Intensive Care Med"},{"issue":"3","key":"10.1016\/j.jcrc.2019.12.022_bb0055","doi-asserted-by":"crossref","first-page":"433","DOI":"10.1007\/s00540-012-1523-2","article-title":"Cardiac surgery-associated acute kidney injury","volume":"27","author":"Parida","year":"2013","journal-title":"J Anesth"},{"issue":"10","key":"10.1016\/j.jcrc.2019.12.022_bb0060","doi-asserted-by":"crossref","first-page":"647","DOI":"10.1056\/NEJM199503093321006","article-title":"Hypoxia of the renal medulla--its implications for disease","volume":"332","author":"Brezis","year":"1995","journal-title":"New Engl J Med"},{"issue":"1","key":"10.1016\/j.jcrc.2019.12.022_bb0065","doi-asserted-by":"crossref","first-page":"291","DOI":"10.1053\/j.jvca.2016.05.029","article-title":"Low-cardiac-output syndrome after cardiac surgery","volume":"31","author":"Lomivorotov","year":"2017","journal-title":"J Cardiothorac Vasc Anesth"},{"issue":"3","key":"10.1016\/j.jcrc.2019.12.022_bb0070","doi-asserted-by":"crossref","first-page":"387","DOI":"10.1053\/j.jvca.2011.09.014","article-title":"Pulse pressure variation predicts fluid responsiveness in elderly patients after coronary artery bypass graft surgery","volume":"26","author":"Yazigi","year":"2012","journal-title":"J Cardiothorac Vasc Anesth"},{"issue":"2","key":"10.1016\/j.jcrc.2019.12.022_bb0075","doi-asserted-by":"crossref","first-page":"364","DOI":"10.1161\/01.CIR.72.2.364","article-title":"Systemic and regional hemodynamic effects of captopril and milrinone administered alone and concomitantly in patients with heart failure","volume":"72","author":"LeJemtel","year":"1985","journal-title":"Circulation"},{"issue":"2","key":"10.1016\/j.jcrc.2019.12.022_bb0080","doi-asserted-by":"crossref","first-page":"128","DOI":"10.1038\/clpt.1986.23","article-title":"Regional blood flow and neurohormonal responses to milrinone in congestive heart failure","volume":"39","author":"Cody","year":"1986","journal-title":"Clin Pharmacol Ther"},{"issue":"5","key":"10.1016\/j.jcrc.2019.12.022_bb0085","doi-asserted-by":"crossref","first-page":"1107","DOI":"10.1016\/S0735-1097(86)80231-5","article-title":"Systemic and coronary effects of intravenous milrinone and dobutamine in congestive heart failure","volume":"7","author":"Grose","year":"1986","journal-title":"J Am Coll Cardiol"},{"issue":"1","key":"10.1016\/j.jcrc.2019.12.022_bb0090","doi-asserted-by":"crossref","DOI":"10.1186\/s13054-018-1969-1","article-title":"Intraoperative milrinone versus dobutamine in cardiac surgery patients: a retrospective cohort study on mortality","volume":"22","author":"Nielsen","year":"2018","journal-title":"Crit Care"},{"issue":"2","key":"10.1016\/j.jcrc.2019.12.022_bb0095","doi-asserted-by":"crossref","first-page":"220","DOI":"10.1053\/j.jvca.2012.08.005","article-title":"Meta-analysis of randomized trials of effect of milrinone on mortality in cardiac surgery: an update","volume":"27","author":"Majure","year":"2013","journal-title":"J Cardiothorac Vasc Anesth"},{"issue":"10","key":"10.1016\/j.jcrc.2019.12.022_bb0100","doi-asserted-by":"crossref","first-page":"2328","DOI":"10.1097\/CCM.0b013e31828e946a","article-title":"Effects of levosimendan on glomerular filtration rate, renal blood flow, and renal oxygenation after cardiac surgery with cardiopulmonary bypass: a randomized placebo-controlled study","volume":"41","author":"Bragadottir","year":"2013","journal-title":"Crit Care Med"},{"issue":"16","key":"10.1016\/j.jcrc.2019.12.022_bb0105","doi-asserted-by":"crossref","DOI":"10.1161\/JAHA.117.008455","article-title":"Differential effects of Levosimendan and Dobutamine on glomerular filtration rate in patients with heart failure and renal impairment: a randomized double-blind controlled trial","volume":"7","author":"Lannemyr","year":"2018","journal-title":"J Am Heart Assoc"},{"issue":"5","key":"10.1016\/j.jcrc.2019.12.022_bb0110","doi-asserted-by":"crossref","first-page":"2152","DOI":"10.1053\/j.jvca.2018.02.039","article-title":"Effect of Levosimendan on renal outcome in cardiac surgery patients with chronic kidney disease and perioperative cardiovascular dysfunction: a substudy of a Multicenter randomized trial","volume":"32","author":"Zangrillo","year":"2018","journal-title":"J Cardiothorac Vasc Anesth"},{"issue":"1","key":"10.1016\/j.jcrc.2019.12.022_bb0115","doi-asserted-by":"crossref","first-page":"79","DOI":"10.1007\/s00134-004-2490-3","article-title":"Differential effects of human atrial natriuretic peptide and furosemide on glomerular filtration rate and renal oxygen consumption in humans","volume":"31","author":"Sward","year":"2005","journal-title":"Intensive Care Med"},{"issue":"3","key":"10.1016\/j.jcrc.2019.12.022_bb0120","doi-asserted-by":"crossref","first-page":"230","DOI":"10.1007\/BF01712242","article-title":"Effects of atrial natriuretic peptide on acute renal impairment in patients with heart failure after cardiac surgery","volume":"22","author":"Valsson","year":"1996","journal-title":"Intensive Care Med"},{"issue":"5","key":"10.1016\/j.jcrc.2019.12.022_bb0125","doi-asserted-by":"crossref","first-page":"536","DOI":"10.1034\/j.1399-6576.2001.045005536.x","article-title":"Long-term infusion of atrial natriuretic peptide (ANP) improves renal blood flow and glomerular filtration rate in clinical acute renal failure","volume":"45","author":"Sward","year":"2001","journal-title":"Acta Anaesthesiol Scand"},{"issue":"1","key":"10.1016\/j.jcrc.2019.12.022_bb0130","doi-asserted-by":"crossref","first-page":"115","DOI":"10.1007\/s00134-008-1206-5","article-title":"Effects of mannitol alone and mannitol plus furosemide on renal oxygen consumption, blood flow and glomerular filtration after cardiac surgery","volume":"35","author":"Redfors","year":"2009","journal-title":"Intensive Care Med"},{"issue":"2","key":"10.1016\/j.jcrc.2019.12.022_bb0135","doi-asserted-by":"crossref","first-page":"138","DOI":"10.1111\/1440-1681.12036","article-title":"Renal oxygenation and haemodynamics in acute kidney injury and chronic kidney disease","volume":"40","author":"Singh","year":"2013","journal-title":"Clin Exp Pharmacol Physiol"},{"issue":"8","key":"10.1016\/j.jcrc.2019.12.022_bb0140","doi-asserted-by":"crossref","first-page":"1052","DOI":"10.1111\/j.1399-6576.2009.02037.x","article-title":"Low-dose vasopressin increases glomerular filtration rate, but impairs renal oxygenation in post-cardiac surgery patients","volume":"53","author":"Bragadottir","year":"2009","journal-title":"Acta Anaesthesiol Scand"},{"issue":"6 Pt 2","key":"10.1016\/j.jcrc.2019.12.022_bb0145","first-page":"R960","article-title":"Control of sodium excretion by angiotensin II: intrarenal mechanisms and blood pressure regulation","volume":"250","author":"Hall","year":"1986","journal-title":"Am J Physiol"},{"key":"10.1016\/j.jcrc.2019.12.022_bb0150","first-page":"48","article-title":"Role of the renin-angiotensin system in control of sodium excretion and arterial pressure","volume":"591","author":"Hall","year":"1990","journal-title":"Acta Physiol Scand Suppl"},{"issue":"5","key":"10.1016\/j.jcrc.2019.12.022_bb0155","doi-asserted-by":"crossref","first-page":"594","DOI":"10.1136\/thx.34.5.594","article-title":"Peripheral vascular resistance and angiotensin II levels during pulsatile and no-pulsatile cardiopulmonary bypass","volume":"34","author":"Taylor","year":"1979","journal-title":"Thorax"},{"issue":"4","key":"10.1016\/j.jcrc.2019.12.022_bb0160","doi-asserted-by":"crossref","first-page":"390","DOI":"10.1007\/BF02471462","article-title":"Effects of pulsatile cardiopulmonary bypass on the renin-angiotensin-aldosterone system following open heart surgery","volume":"18","author":"Nagaoka","year":"1988","journal-title":"Jpn J Surg"}],"container-title":["Journal of Critical Care"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0883944119314285?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0883944119314285?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,10]],"date-time":"2025-10-10T19:45:00Z","timestamp":1760125500000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0883944119314285"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,6]]},"references-count":32,"alternative-id":["S0883944119314285"],"URL":"https:\/\/doi.org\/10.1016\/j.jcrc.2019.12.022","relation":{},"ISSN":["0883-9441"],"issn-type":[{"value":"0883-9441","type":"print"}],"subject":[],"published":{"date-parts":[[2020,6]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Effects of milrinone on renal perfusion, filtration and oxygenation in patients with acute heart failure and low cardiac output early after cardiac surgery","name":"articletitle","label":"Article Title"},{"value":"Journal of Critical Care","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.jcrc.2019.12.022","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2020 Elsevier Inc. All rights reserved.","name":"copyright","label":"Copyright"}]}}