{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,28]],"date-time":"2026-05-28T01:37:38Z","timestamp":1779932258841,"version":"3.53.1"},"reference-count":18,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2021,10,1]],"date-time":"2021-10-01T00:00:00Z","timestamp":1633046400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2021,10,1]],"date-time":"2021-10-01T00:00:00Z","timestamp":1633046400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2021,10,1]],"date-time":"2021-10-01T00:00:00Z","timestamp":1633046400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2021,10,1]],"date-time":"2021-10-01T00:00:00Z","timestamp":1633046400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2021,10,1]],"date-time":"2021-10-01T00:00:00Z","timestamp":1633046400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2021,10,1]],"date-time":"2021-10-01T00:00:00Z","timestamp":1633046400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2021,10,1]],"date-time":"2021-10-01T00:00:00Z","timestamp":1633046400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Journal of Critical Care"],"published-print":{"date-parts":[[2021,10]]},"DOI":"10.1016\/j.jcrc.2021.05.011","type":"journal-article","created":{"date-parts":[[2021,5,25]],"date-time":"2021-05-25T12:15:42Z","timestamp":1621944942000},"page":"86-90","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":8,"special_numbering":"C","title":["Comparison of fixed dose versus train-of-four titration of cisatracurium in acute respiratory distress syndrome"],"prefix":"10.1016","volume":"65","author":[{"given":"Melissa L.","family":"Thompson Bastin","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rebecca R.","family":"Smith","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Brittany D.","family":"Bissell","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Heather N.","family":"Wolf","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alexandra M.","family":"Wiegand","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Megan E.","family":"Cavagnini","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yahya","family":"Ahmad","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alexander H.","family":"Flannery","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"issue":"9","key":"10.1016\/j.jcrc.2021.05.011_bb0005","doi-asserted-by":"crossref","first-page":"899","DOI":"10.1177\/1060028020910132","article-title":"To block or not: updates in neuromuscular blockade in acute respiratory distress syndrome","volume":"54","author":"Mefford","year":"2020","journal-title":"Ann Pharmacother"},{"issue":"12","key":"10.1016\/j.jcrc.2021.05.011_bb0010","doi-asserted-by":"crossref","first-page":"1107","DOI":"10.1056\/NEJMoa1005372","article-title":"Neuromuscular blockers in early acute respiratory distress syndrome","volume":"363","author":"Papazian","year":"2010","journal-title":"N Engl J Med"},{"issue":"21","key":"10.1016\/j.jcrc.2021.05.011_bb0015","doi-asserted-by":"crossref","first-page":"1997","DOI":"10.1056\/NEJMoa1901686","article-title":"Early neuromuscular blockade in the acute respiratory distress syndrome","volume":"380","author":"National Heart","year":"2019","journal-title":"N Engl J Med"},{"issue":"1","key":"10.1016\/j.jcrc.2021.05.011_bb0020","doi-asserted-by":"crossref","first-page":"8","DOI":"10.1097\/00005650-199801000-00004","article-title":"Comorbidity measures for use with administrative data","volume":"36","author":"Elixhauser","year":"1998","journal-title":"Med Care"},{"issue":"11","key":"10.1016\/j.jcrc.2021.05.011_bb0025","doi-asserted-by":"crossref","first-page":"1793","DOI":"10.1097\/00003246-199811000-00016","article-title":"Use of the SOFA score to assess the incidence of organ dysfunction\/failure in intensive care units: results of a multicenter, prospective study. Working group on \u201csepsis-related problems\u201d of the European Society of Intensive Care Medicine","volume":"26","author":"Vincent","year":"1998","journal-title":"Crit Care Med"},{"issue":"2","key":"10.1016\/j.jcrc.2021.05.011_bb0030","doi-asserted-by":"crossref","first-page":"410","DOI":"10.1378\/chest.07-0617","article-title":"Comparison of the SpO2\/FIO2 ratio and the PaO2\/FIO2 ratio in patients with acute lung injury or ARDS","volume":"132","author":"Rice","year":"2007","journal-title":"Chest"},{"issue":"1","key":"10.1016\/j.jcrc.2021.05.011_bb0035","doi-asserted-by":"crossref","first-page":"69","DOI":"10.1186\/s13613-019-0540-9","article-title":"Formal guidelines: management of acute respiratory distress syndrome","volume":"9","author":"Papazian","year":"2019","journal-title":"Ann Intensive Care"},{"issue":"11","key":"10.1016\/j.jcrc.2021.05.011_bb0040","doi-asserted-by":"crossref","first-page":"2079","DOI":"10.1097\/CCM.0000000000002027","article-title":"Clinical practice guidelines for sustained neuromuscular blockade in the adult critically ill patient","volume":"44","author":"Murray","year":"2016","journal-title":"Crit Care Med"},{"issue":"1","key":"10.1016\/j.jcrc.2021.05.011_bb0045","doi-asserted-by":"crossref","first-page":"113","DOI":"10.1097\/01.CCM.0000104114.72614.BC","article-title":"Effect of neuromuscular blocking agents on gas exchange in patients presenting with acute respiratory distress syndrome","volume":"32","author":"Gainnier","year":"2004","journal-title":"Crit Care Med"},{"issue":"11","key":"10.1016\/j.jcrc.2021.05.011_bb0050","doi-asserted-by":"crossref","first-page":"2749","DOI":"10.1097\/01.CCM.0000239435.87433.0D","article-title":"Neuromuscular blocking agents decrease inflammatory response in patients presenting with acute respiratory distress syndrome","volume":"34","author":"Forel","year":"2006","journal-title":"Crit Care Med"},{"issue":"4","key":"10.1016\/j.jcrc.2021.05.011_bb0055","doi-asserted-by":"crossref","first-page":"588","DOI":"10.1097\/CCM.0000000000004171","article-title":"Rescue neuromuscular blockade in acute respiratory distress syndrome should not be flat dose","volume":"48","author":"Flannery","year":"2020","journal-title":"Crit Care Med"},{"issue":"4","key":"10.1016\/j.jcrc.2021.05.011_bb0060","doi-asserted-by":"crossref","first-page":"591","DOI":"10.1097\/CCM.0000000000004198","article-title":"Rescue neuromuscular blockade in acute respiratory distress syndrome should be flat dose","volume":"48","author":"Co","year":"2020","journal-title":"Crit Care Med"},{"issue":"1","key":"10.1016\/j.jcrc.2021.05.011_bb0065","doi-asserted-by":"crossref","first-page":"132","DOI":"10.1097\/ALN.0000000000000907","article-title":"Neuromuscular blocking agent cisatracurium attenuates lung injury by inhibition of nicotinic acetylcholine receptor-alpha1","volume":"124","author":"Fanelli","year":"2016","journal-title":"Anesthesiology"},{"issue":"1","key":"10.1016\/j.jcrc.2021.05.011_bb0070","doi-asserted-by":"crossref","first-page":"124","DOI":"10.1513\/AnnalsATS.201608-629OT","article-title":"Design and rationale of the reevaluation of systemic early neuromuscular blockade trial for acute respiratory distress syndrome","volume":"14","author":"Huang","year":"2017","journal-title":"Ann Am Thorac Soc"},{"issue":"1","key":"10.1016\/j.jcrc.2021.05.011_bb0075","doi-asserted-by":"crossref","first-page":"19","DOI":"10.1055\/s-0039-1684049","article-title":"Acute respiratory distress syndrome phenotypes","volume":"40","author":"Reilly","year":"2019","journal-title":"Semin Respir Crit Care Med"},{"issue":"1","key":"10.1016\/j.jcrc.2021.05.011_bb0080","doi-asserted-by":"crossref","first-page":"79","DOI":"10.1186\/s13613-017-0305-2","article-title":"How to reduce cisatracurium consumption in ARDS patients: the TOF-ARDS study","volume":"7","author":"Hraiech","year":"2017","journal-title":"Ann Intensive Care"},{"key":"10.1016\/j.jcrc.2021.05.011_bb0085","doi-asserted-by":"crossref","first-page":"534","DOI":"10.1097\/01.ccm.0000551860.82758.cb","article-title":"Fixed versus titration-based dosing of cisatracurium in acute respiratory distress syndrome","volume":"47","author":"Brookbank","year":"2019","journal-title":"Crit Care Med"},{"issue":"2","key":"10.1016\/j.jcrc.2021.05.011_bb0090","doi-asserted-by":"crossref","first-page":"288","DOI":"10.1097\/CCM.0000000000000715","article-title":"Fluid management with a simplified conservative protocol for the acute respiratory distress syndrome*","volume":"43","author":"Grissom","year":"2015","journal-title":"Crit Care Med"}],"container-title":["Journal of Critical Care"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0883944121000915?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0883944121000915?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,10]],"date-time":"2025-10-10T19:47:57Z","timestamp":1760125677000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0883944121000915"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,10]]},"references-count":18,"alternative-id":["S0883944121000915"],"URL":"https:\/\/doi.org\/10.1016\/j.jcrc.2021.05.011","relation":{},"ISSN":["0883-9441"],"issn-type":[{"value":"0883-9441","type":"print"}],"subject":[],"published":{"date-parts":[[2021,10]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Comparison of fixed dose versus train-of-four titration of cisatracurium in acute respiratory distress syndrome","name":"articletitle","label":"Article Title"},{"value":"Journal of Critical Care","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.jcrc.2021.05.011","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2021 Elsevier Inc. All rights reserved.","name":"copyright","label":"Copyright"}]}}