{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,11]],"date-time":"2025-10-11T02:12:43Z","timestamp":1760148763177,"version":"build-2065373602"},"reference-count":11,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2022,2,1]],"date-time":"2022-02-01T00:00:00Z","timestamp":1643673600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2022,2,1]],"date-time":"2022-02-01T00:00:00Z","timestamp":1643673600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2022,2,1]],"date-time":"2022-02-01T00:00:00Z","timestamp":1643673600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2022,2,1]],"date-time":"2022-02-01T00:00:00Z","timestamp":1643673600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2022,2,1]],"date-time":"2022-02-01T00:00:00Z","timestamp":1643673600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2022,2,1]],"date-time":"2022-02-01T00:00:00Z","timestamp":1643673600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2022,2,1]],"date-time":"2022-02-01T00:00:00Z","timestamp":1643673600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"funder":[{"DOI":"10.13039\/100000057","name":"National Institute of General Medical Sciences","doi-asserted-by":"publisher","award":["1F32GM133061-01"],"award-info":[{"award-number":["1F32GM133061-01"]}],"id":[{"id":"10.13039\/100000057","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Journal of Critical Care"],"published-print":{"date-parts":[[2022,2]]},"DOI":"10.1016\/j.jcrc.2021.10.017","type":"journal-article","created":{"date-parts":[[2021,10,29]],"date-time":"2021-10-29T18:34:03Z","timestamp":1635532443000},"page":"85-87","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":4,"special_numbering":"C","title":["Death due to irreversible hypoxemic respiratory failure in ARDSnet clinical trials"],"prefix":"10.1016","volume":"67","author":[{"given":"Nicholas A.","family":"Bosch","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ming-Ming","family":"Lee","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mallory N.","family":"LeSieur","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Anica C.","family":"Law","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Allan J.","family":"Walkey","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.jcrc.2021.10.017_bb0005","doi-asserted-by":"crossref","first-page":"327","DOI":"10.1056\/NEJMoa032193","article-title":"Higher versus lower positive end-expiratory pressures in patients with the acute respiratory distress syndrome","volume":"351","year":"2004","journal-title":"N Engl J Med"},{"key":"10.1016\/j.jcrc.2021.10.017_bb0010","doi-asserted-by":"crossref","first-page":"1671","DOI":"10.1056\/NEJMoa051693","article-title":"Efficacy and safety of corticosteroids for persistent acute respiratory distress syndrome","volume":"354","year":"2006","journal-title":"N Engl J Med"},{"key":"10.1016\/j.jcrc.2021.10.017_bb0015","doi-asserted-by":"crossref","first-page":"788","DOI":"10.1001\/jama.2016.0291","article-title":"Epidemiology, patterns of care, and mortality for patients with acute respiratory distress syndrome in intensive care units in 50 countries","volume":"315","author":"Bellani","year":"2016","journal-title":"JAMA"},{"key":"10.1016\/j.jcrc.2021.10.017_bb0020","doi-asserted-by":"crossref","first-page":"525","DOI":"10.1378\/chest.128.2.525","article-title":"Causes and timing of death in patients with ARDS","volume":"128","author":"Stapleton","year":"2005","journal-title":"CHEST"},{"key":"10.1016\/j.jcrc.2021.10.017_bb0025","doi-asserted-by":"crossref","first-page":"1301","DOI":"10.1056\/NEJM200005043421801","article-title":"Ventilation with lower tidal volumes as compared with traditional tidal volumes for acute lung injury and the acute respiratory distress syndrome","volume":"342","year":"2000","journal-title":"N Engl J Med"},{"key":"10.1016\/j.jcrc.2021.10.017_bb0030","doi-asserted-by":"crossref","first-page":"2564","DOI":"10.1056\/NEJMoa062200","article-title":"Comparison of two fluid-management strategies in acute lung injury","volume":"354","year":"2006","journal-title":"N Engl J Med"},{"key":"10.1016\/j.jcrc.2021.10.017_bb0035","doi-asserted-by":"crossref","first-page":"795","DOI":"10.1001\/jama.2012.137","article-title":"Initial trophic vs full enteral feeding in patients with acute lung injury: the EDEN randomized trial","volume":"307","author":"The National Heart, Lung, and Blood Institute Acute Respiratory Distress Syndrome (ARDS) Clinical Trials Network","year":"2012","journal-title":"JAMA"},{"key":"10.1016\/j.jcrc.2021.10.017_bb0040","doi-asserted-by":"crossref","first-page":"561","DOI":"10.1164\/rccm.201012-2090OC","article-title":"Randomized, Placebo-controlled clinical trial of an aerosolized \u03b22-agonist for treatment of acute lung injury","volume":"184","year":"2011","journal-title":"Am J Respir Crit Care Med"},{"key":"10.1016\/j.jcrc.2021.10.017_bb0045","doi-asserted-by":"crossref","first-page":"2191","DOI":"10.1056\/NEJMoa1401520","article-title":"Rosuvastatin for sepsis-associated acute respiratory distress syndrome","volume":"370","year":"2014","journal-title":"N Engl J Med"},{"key":"10.1016\/j.jcrc.2021.10.017_bb0050","article-title":"Validating measures of disease severity in acute respiratory distress syndrome","author":"Sedhai","year":"2020","journal-title":"Ann ATS"},{"key":"10.1016\/j.jcrc.2021.10.017_bb0055","doi-asserted-by":"crossref","first-page":"81","DOI":"10.1053\/j.semtcvs.2015.07.005","article-title":"Trends in U.S. extracorporeal membrane oxygenation use and outcomes: 2002\u20132012","volume":"27","author":"McCarthy","year":"2015","journal-title":"Semin Thorac Cardiovasc Surg"}],"container-title":["Journal of Critical Care"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0883944121002392?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0883944121002392?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,10]],"date-time":"2025-10-10T19:49:27Z","timestamp":1760125767000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0883944121002392"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,2]]},"references-count":11,"alternative-id":["S0883944121002392"],"URL":"https:\/\/doi.org\/10.1016\/j.jcrc.2021.10.017","relation":{},"ISSN":["0883-9441"],"issn-type":[{"type":"print","value":"0883-9441"}],"subject":[],"published":{"date-parts":[[2022,2]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Death due to irreversible hypoxemic respiratory failure in ARDSnet clinical trials","name":"articletitle","label":"Article Title"},{"value":"Journal of Critical Care","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.jcrc.2021.10.017","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2021 Elsevier Inc. All rights reserved.","name":"copyright","label":"Copyright"}]}}