{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,3]],"date-time":"2026-10-03T16:08:00Z","timestamp":1791043680747,"version":"4.1.0"},"reference-count":31,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2022,10,1]],"date-time":"2022-10-01T00:00:00Z","timestamp":1664582400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2023,6,11]],"date-time":"2023-06-11T00:00:00Z","timestamp":1686441600000},"content-version":"am","delay-in-days":253,"URL":"http:\/\/www.elsevier.com\/open-access\/userlicense\/1.0\/"},{"start":{"date-parts":[[2022,10,1]],"date-time":"2022-10-01T00:00:00Z","timestamp":1664582400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2022,10,1]],"date-time":"2022-10-01T00:00:00Z","timestamp":1664582400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2022,10,1]],"date-time":"2022-10-01T00:00:00Z","timestamp":1664582400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2022,10,1]],"date-time":"2022-10-01T00:00:00Z","timestamp":1664582400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2022,10,1]],"date-time":"2022-10-01T00:00:00Z","timestamp":1664582400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"content-domain":{"domain":["clinicalkey.fr","clinicalkey.jp","clinicalkey.es","clinicalkey.com.au","clinicalkey.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Journal of Critical Care"],"published-print":{"date-parts":[[2022,10]]},"DOI":"10.1016\/j.jcrc.2022.154090","type":"journal-article","created":{"date-parts":[[2022,6,11]],"date-time":"2022-06-11T15:59:14Z","timestamp":1654963154000},"page":"154090","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":10,"special_numbering":"C","title":["Venoarterial extracorporeal membrane oxygenation flow or dobutamine to improve microcirculation during ECMO for refractory cardiogenic shock"],"prefix":"10.1016","volume":"71","author":[{"given":"Juliette","family":"Chommeloux","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Santiago","family":"Montero","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Guillaume","family":"Franchineau","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Guillaume","family":"Lebreton","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nicolas","family":"Br\u00e9chot","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Petra","family":"Barhoum","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lucie","family":"Lef\u00e8vre","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marc Pineton","family":"de Chambrun","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Guillaume","family":"H\u00e9kimian","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Charles-Edouard","family":"Luyt","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alain","family":"Combes","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Matthieu","family":"Schmidt","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.jcrc.2022.154090_bb0005","doi-asserted-by":"crossref","first-page":"91","DOI":"10.1016\/j.ahj.2003.07.006","article-title":"Microvascular alterations in patients with acute severe heart failure and cardiogenic shock","volume":"147","author":"De Backer","year":"2004","journal-title":"Am Heart J"},{"key":"10.1016\/j.jcrc.2022.154090_bb0010","doi-asserted-by":"crossref","first-page":"366","DOI":"10.1093\/bja\/aev163","article-title":"Microcirculatory dysfunction and resuscitation: why, when, and how","volume":"115","author":"Moore","year":"2015","journal-title":"Br J Anaesth"},{"key":"10.1016\/j.jcrc.2022.154090_bb0015","doi-asserted-by":"crossref","first-page":"791","DOI":"10.1097\/CCM.0b013e3182742e8b","article-title":"Microcirculatory alterations in patients with severe sepsis: impact of time of assessment and relationship with outcome","volume":"41","author":"De Backer","year":"2013","journal-title":"Crit Care Med"},{"key":"10.1016\/j.jcrc.2022.154090_bb0020","doi-asserted-by":"crossref","first-page":"73","DOI":"10.4161\/viru.26482","article-title":"Pathophysiology of microcirculatory dysfunction and the pathogenesis of septic shock","volume":"5","author":"De Backer","year":"2014","journal-title":"Virulence"},{"key":"10.1016\/j.jcrc.2022.154090_bb0025","doi-asserted-by":"crossref","first-page":"3032","DOI":"10.1093\/eurheartj\/ehq324","article-title":"Impaired microcirculation predicts poor outcome of patients with acute myocardial infarction complicated by cardiogenic shock","volume":"31","author":"den Uil","year":"2010","journal-title":"Eur Heart J"},{"key":"10.1016\/j.jcrc.2022.154090_bb0030","doi-asserted-by":"crossref","first-page":"344","DOI":"10.1186\/s13054-016-1519-7","article-title":"Microcirculatory assessment of patients under VA-ECMO","volume":"20","author":"Kara","year":"2016","journal-title":"Crit Care"},{"key":"10.1016\/j.jcrc.2022.154090_bb0035","doi-asserted-by":"crossref","first-page":"2769","DOI":"10.1016\/j.jacc.2014.03.046","article-title":"Extracorporeal membrane oxygenation in cardiopulmonary disease in adults","volume":"63","author":"Abrams","year":"2014","journal-title":"J Am Coll Cardiol"},{"key":"10.1016\/j.jcrc.2022.154090_bb0040","doi-asserted-by":"crossref","first-page":"e9","DOI":"10.1097\/CCM.0000000000004072","article-title":"Microcirculation evolution in patients on Venoarterial extracorporeal membrane oxygenation for refractory cardiogenic shock","volume":"48","author":"Chommeloux","year":"2020","journal-title":"Crit Care Med"},{"key":"10.1016\/j.jcrc.2022.154090_bb0045","doi-asserted-by":"crossref","first-page":"1616","DOI":"10.1097\/CCM.0b013e31828a2370","article-title":"Venoarterial extracorporeal membrane oxygenation support for refractory cardiovascular dysfunction during severe bacterial septic shock","volume":"41","author":"Br\u00e9chot","year":"2013","journal-title":"Crit Care Med"},{"key":"10.1016\/j.jcrc.2022.154090_bb0050","doi-asserted-by":"crossref","first-page":"2075","DOI":"10.1097\/CCM.0000000000000410","article-title":"Intra-aortic balloon pump effects on macrocirculation and microcirculation in cardiogenic shock patients supported by venoarterial extracorporeal membrane oxygenation*","volume":"42","author":"Petroni","year":"2014","journal-title":"Crit Care Med"},{"key":"10.1016\/j.jcrc.2022.154090_bb0055","article-title":"Effect of an intra-aortic balloon pump with venoarterial extracorporeal membrane oxygenation on mortality of patients with cardiogenic shock: a systematic review and meta-analysis","author":"Li","year":"2018","journal-title":"Eur J Cardio-Thorac Surg"},{"key":"10.1016\/j.jcrc.2022.154090_bb0060","doi-asserted-by":"crossref","first-page":"1738","DOI":"10.1007\/s00134-011-2358-2","article-title":"Predictors of successful extracorporeal membrane oxygenation (ECMO) weaning after assistance for refractory cardiogenic shock","volume":"37","author":"Aissaoui","year":"2011","journal-title":"Intensive Care Med"},{"key":"10.1016\/j.jcrc.2022.154090_bb0065","doi-asserted-by":"crossref","first-page":"902","DOI":"10.1007\/s00134-015-3663-y","article-title":"How to wean a patient from veno-arterial extracorporeal membrane oxygenation","volume":"41","author":"Aissaoui","year":"2015","journal-title":"Intensive Care Med"},{"key":"10.1016\/j.jcrc.2022.154090_bb0070","doi-asserted-by":"crossref","first-page":"15101","DOI":"10.1364\/OE.15.015101","article-title":"Sidestream dark field (SDF) imaging: a novel stroboscopic LED ring-based imaging modality for clinical assessment of the microcirculation","volume":"15","author":"Goedhart","year":"2007","journal-title":"Opt Express"},{"key":"10.1016\/j.jcrc.2022.154090_bb0075","doi-asserted-by":"crossref","first-page":"281","DOI":"10.1007\/s00134-018-5070-7","article-title":"Second consensus on the assessment of sublingual microcirculation in critically ill patients: results from a task force of the European Society of Intensive Care Medicine","volume":"44","author":"Ince","year":"2018","journal-title":"Intensive Care Med"},{"key":"10.1016\/j.jcrc.2022.154090_bb0080","doi-asserted-by":"crossref","first-page":"913","DOI":"10.1016\/j.jcrc.2013.06.015","article-title":"The microcirculation image quality score: development and preliminary evaluation of a proposed approach to grading quality of image acquisition for bedside videomicroscopy","volume":"28","author":"Massey","year":"2013","journal-title":"J Crit Care"},{"key":"10.1016\/j.jcrc.2022.154090_bb0085","doi-asserted-by":"crossref","first-page":"R101","DOI":"10.1186\/cc6118","article-title":"How to evaluate the microcirculation: report of a round table conference","volume":"11","author":"De Backer","year":"2007","journal-title":"Crit Care Lond Engl"},{"key":"10.1016\/j.jcrc.2022.154090_bb0090","doi-asserted-by":"crossref","first-page":"265","DOI":"10.1186\/s13054-017-1855-2","article-title":"Functional evaluation of sublingual microcirculation indicates successful weaning from VA-ECMO in cardiogenic shock","volume":"21","author":"Akin","year":"2017","journal-title":"Crit Care"},{"key":"10.1016\/j.jcrc.2022.154090_bb0095","doi-asserted-by":"crossref","first-page":"200","DOI":"10.1186\/s13054-018-2081-2","article-title":"Investigation of microcirculation in patients with venoarterial extracorporeal membrane oxygenation life support","volume":"22","author":"Yeh","year":"2018","journal-title":"Crit Care Lond Engl"},{"key":"10.1016\/j.jcrc.2022.154090_bb0100","doi-asserted-by":"crossref","first-page":"1121","DOI":"10.1097\/CCM.0b013e3181962a5f","article-title":"Changes in buccal microcirculation following extracorporeal membrane oxygenation in term neonates with severe respiratory failure","volume":"37","author":"Top","year":"2009","journal-title":"Crit Care Med"},{"key":"10.1016\/j.jcrc.2022.154090_bb0105","article-title":"The microcirculation is unchanged in neonates with severe respiratory failure after the initiation of ECMO treatment","volume":"2012","author":"Top","year":"2012","journal-title":"Crit Care Res Pract"},{"key":"10.1016\/j.jcrc.2022.154090_bb0110","doi-asserted-by":"crossref","first-page":"1294","DOI":"10.1007\/s00134-008-1007-x","article-title":"Disparity between skin perfusion and sublingual microcirculatory alterations in severe sepsis and septic shock: a prospective observational study","volume":"34","author":"Boerma","year":"2008","journal-title":"Intensive Care Med"},{"key":"10.1016\/j.jcrc.2022.154090_bb0115","doi-asserted-by":"crossref","first-page":"27","DOI":"10.3233\/CH-16156","article-title":"Effect of increasing mean arterial blood pressure on microcirculation in patients with cardiogenic shock supported by extracorporeal membrane oxygenation","volume":"70","author":"Du","year":"2018","journal-title":"Clin Hemorheol Microcirc"},{"key":"10.1016\/j.jcrc.2022.154090_bb0120","doi-asserted-by":"crossref","first-page":"207","DOI":"10.1177\/0267659115590481","article-title":"Microcirculatory response during on-pump versus off-pump coronary artery bypass graft surgery","volume":"31","author":"Bienz","year":"2016","journal-title":"Perfusion"},{"key":"10.1016\/j.jcrc.2022.154090_bb0125","doi-asserted-by":"crossref","first-page":"336","DOI":"10.1053\/j.jvca.2013.05.026","article-title":"Microcirculatory perfusion is preserved during off-pump but not on-pump cardiac surgery","volume":"28","author":"Koning","year":"2014","journal-title":"J Cardiothorac Vasc Anesth"},{"key":"10.1016\/j.jcrc.2022.154090_bb0130","first-page":"66","article-title":"Hemodynamics of mechanical circulatory support","author":"Burkhoff","year":"2015","journal-title":"J Am Coll Cardiol"},{"key":"10.1016\/j.jcrc.2022.154090_bb0135","doi-asserted-by":"crossref","first-page":"2482","DOI":"10.1097\/CCM.0000000000000549","article-title":"Randomized controlled trial of inhaled nitric oxide for the treatment of microcirculatory dysfunction in patients with sepsis*","volume":"42","author":"Trzeciak","year":"2014","journal-title":"Crit Care Med"},{"key":"10.1016\/j.jcrc.2022.154090_bb0140","doi-asserted-by":"crossref","first-page":"269","DOI":"10.1097\/SHK.0000000000000777","article-title":"Vasodilators in septic shock resuscitation: a clinical perspective","volume":"47","author":"Corr\u00eaa","year":"2017","journal-title":"Shock Augusta Ga"},{"key":"10.1016\/j.jcrc.2022.154090_bb0145","doi-asserted-by":"crossref","first-page":"403","DOI":"10.1097\/01.CCM.0000198107.61493.5A","article-title":"The effects of dobutamine on microcirculatory alterations in patients with septic shock are independent of its systemic effects","volume":"34","author":"De Backer","year":"2006","journal-title":"Crit Care Med"},{"key":"10.1016\/j.jcrc.2022.154090_bb0150","doi-asserted-by":"crossref","first-page":"R232","DOI":"10.1186\/cc9387","article-title":"Levosimendan for resuscitating the microcirculation in patients with septic shock: a randomized controlled study","volume":"14","author":"Morelli","year":"2010","journal-title":"Crit Care Lond Engl"},{"key":"10.1016\/j.jcrc.2022.154090_bb0155","doi-asserted-by":"crossref","first-page":"2046","DOI":"10.1016\/j.athoracsur.2012.05.065","article-title":"Pulsatile versus nonpulsatile flow during cardiopulmonary bypass: microcirculatory and systemic effects","volume":"94","author":"O\u2019Neil","year":"2012","journal-title":"Ann Thorac Surg"}],"updated-by":[{"DOI":"10.1016\/j.jcrc.2022.154193","type":"erratum","label":"Erratum","source":"publisher","updated":{"date-parts":[[2022,12,1]],"date-time":"2022-12-01T00:00:00Z","timestamp":1669852800000}}],"container-title":["Journal of Critical Care"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0883944122001198?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0883944122001198?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2023,3,5]],"date-time":"2023-03-05T02:58:12Z","timestamp":1677985092000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0883944122001198"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,10]]},"references-count":31,"alternative-id":["S0883944122001198"],"URL":"https:\/\/doi.org\/10.1016\/j.jcrc.2022.154090","relation":{"erratum":[{"id-type":"doi","id":"10.1016\/j.jcrc.2022.154193","asserted-by":"object"}]},"ISSN":["0883-9441"],"issn-type":[{"value":"0883-9441","type":"print"}],"subject":[],"published":{"date-parts":[[2022,10]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Venoarterial extracorporeal membrane oxygenation flow or dobutamine to improve microcirculation during ECMO for refractory cardiogenic shock","name":"articletitle","label":"Article Title"},{"value":"Journal of Critical Care","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.jcrc.2022.154090","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2022 Elsevier Inc. All rights reserved.","name":"copyright","label":"Copyright"}],"article-number":"154090"}}