{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,3]],"date-time":"2026-04-03T01:59:19Z","timestamp":1775181559691,"version":"3.50.1"},"reference-count":35,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2025,6,1]],"date-time":"2025-06-01T00:00:00Z","timestamp":1748736000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2025,6,1]],"date-time":"2025-06-01T00:00:00Z","timestamp":1748736000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2025,4,1]],"date-time":"2025-04-01T00:00:00Z","timestamp":1743465600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/100000897","name":"Cystic Fibrosis Foundation","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100000897","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","jctejournal.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Journal of Clinical & Translational Endocrinology"],"published-print":{"date-parts":[[2025,6]]},"DOI":"10.1016\/j.jcte.2025.100391","type":"journal-article","created":{"date-parts":[[2025,4,4]],"date-time":"2025-04-04T23:06:00Z","timestamp":1743807960000},"page":"100391","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":1,"special_numbering":"C","title":["Cholesterol and triglyceride concentrations following 12\u201318\u00a0months of clinically prescribed elexacaftor-tezacaftor-ivacaftor\u2014PROMISE sub-study"],"prefix":"10.1016","volume":"40","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-3290-7355","authenticated-orcid":false,"given":"Rosara","family":"Bass","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Michael","family":"Stalvey","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"George","family":"Solomon","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Steven","family":"Rowe","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"David","family":"Nichols","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sarah Jane","family":"Schwarzenberg","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Steven","family":"Freedman","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Rachel","family":"Walega","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Andrea","family":"Kelly","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"issue":"6","key":"10.1016\/j.jcte.2025.100391_b0005","doi-asserted-by":"crossref","first-page":"583","DOI":"10.1016\/0895-4356(88)90063-7","article-title":"A comparison of survival, growth, and pulmonary function in patients with cystic fibrosis in Boston and Toronto","volume":"41","author":"Corey","year":"1988","journal-title":"J Clin Epidemiol"},{"issue":"5","key":"10.1016\/j.jcte.2025.100391_b0010","doi-asserted-by":"crossref","first-page":"832","DOI":"10.1016\/j.jada.2008.02.020","article-title":"Evidence-based practice recommendations for nutrition-related management of children and adults with cystic fibrosis and pancreatic insufficiency: results of a systematic review","volume":"108","author":"Stallings","year":"2008","journal-title":"J Am Diet Assoc"},{"issue":"4","key":"10.1016\/j.jcte.2025.100391_b0015","doi-asserted-by":"crossref","first-page":"872","DOI":"10.3945\/ajcn.112.051409","article-title":"Longitudinal trends in nutritional status and the relation between lung function and BMI in cystic fibrosis: a population-based cohort study","volume":"97","author":"Stephenson","year":"2013","journal-title":"Am J Clin Nutr"},{"issue":"6","key":"10.1016\/j.jcte.2025.100391_b0020","doi-asserted-by":"crossref","first-page":"775","DOI":"10.1055\/s-0039-1696726","article-title":"Growth and nutrition in cystic fibrosis","volume":"40","author":"Brownell","year":"2019","journal-title":"Semin Respir Crit Care Med"},{"issue":"6","key":"10.1016\/j.jcte.2025.100391_b0025","doi-asserted-by":"crossref","first-page":"1005","DOI":"10.1093\/ajcn\/75.6.1005","article-title":"Abnormal lipid concentrations in cystic fibrosis","volume":"75","author":"Figueroa","year":"2002","journal-title":"Am J Clin Nutr"},{"issue":"1","key":"10.1016\/j.jcte.2025.100391_b0030","doi-asserted-by":"crossref","first-page":"24","DOI":"10.1016\/j.jcf.2009.09.002","article-title":"Prevalence of dyslipidemia in adults with cystic fibrosis","volume":"9","author":"Rhodes","year":"2010","journal-title":"J Cyst Fibros"},{"key":"10.1016\/j.jcte.2025.100391_b0035","unstructured":"Foundation CF. Patient Registry. 2023-05-02]; Available from: https:\/\/www.cff.org\/medical-professionals\/patient-registry."},{"issue":"5","key":"10.1016\/j.jcte.2025.100391_b0040","doi-asserted-by":"crossref","first-page":"777","DOI":"10.1016\/j.jcf.2022.03.010","article-title":"Obesity in Cystic fibrosis: prevalence, trends and associated factors data from the US cystic fibrosis foundation patient registry","volume":"21","author":"Szentpetery","year":"2022","journal-title":"J Cyst Fibros"},{"key":"10.1016\/j.jcte.2025.100391_b0045","article-title":"Coronary artery disease in patients with cystic fibrosis - A case series and review of the literature","volume":"30","author":"Sandouk","year":"2022","journal-title":"J Clin Transl Endocrinol"},{"issue":"4","key":"10.1016\/j.jcte.2025.100391_b0050","doi-asserted-by":"crossref","DOI":"10.1183\/13993003.00174-2023","article-title":"Prevalence, risk factors and outcomes of cardiac disease in cystic fibrosis: a multinational retrospective cohort study","volume":"62","author":"Frost","year":"2023","journal-title":"Eur Respir J"},{"issue":"5","key":"10.1016\/j.jcte.2025.100391_b0055","doi-asserted-by":"crossref","first-page":"529","DOI":"10.1164\/rccm.202108-1986OC","article-title":"Clinical effectiveness of elexacaftor\/tezacaftor\/ivacaftor in people with cystic fibrosis: a clinical trial","volume":"205","author":"Nichols","year":"2022","journal-title":"Am J Respir Crit Care Med"},{"key":"10.1016\/j.jcte.2025.100391_b0075","doi-asserted-by":"crossref","unstructured":"Expert Panel on Detection, Evaluation, and Treatment of High Blood Cholesterol in Adults. Executive Summary of The Third Report of The National Cholesterol Education Program. JAMA. 285(19): p. 2486-2497.","DOI":"10.1001\/jama.285.19.2486"},{"issue":"24","key":"10.1016\/j.jcte.2025.100391_b0080","doi-asserted-by":"crossref","first-page":"e285","DOI":"10.1016\/j.jacc.2018.11.003","article-title":"2018 AHA\/ACC\/AACVPR\/AAPA\/ABC\/ACPM\/ADA\/AGS\/APhA\/ASPC\/NLA\/PCNA Guideline on the management of blood cholesterol: a report of the American College of Cardiology\/American Heart Association TaskForceonClinical Practice Guidelines","volume":"73","author":"Grundy","year":"2019","journal-title":"J Am Coll Cardiol"},{"issue":"6","key":"10.1016\/j.jcte.2025.100391_b0085","doi-asserted-by":"crossref","first-page":"1324","DOI":"10.1183\/09031936.00080312","article-title":"Multi-ethnic reference values for spirometry for the 3-95-yr age range: the global lung function 2012 equations","volume":"40","author":"Quanjer","year":"2012","journal-title":"Eur Respir J"},{"issue":"10","key":"10.1016\/j.jcte.2025.100391_b0090","doi-asserted-by":"crossref","first-page":"1056","DOI":"10.1161\/CIRCULATIONAHA.106.620864","article-title":"Distribution of lipoproteins by age and gender in adolescents","volume":"114","author":"Jolliffe","year":"2006","journal-title":"Circulation"},{"issue":"3","key":"10.1016\/j.jcte.2025.100391_b0065","doi-asserted-by":"crossref","first-page":"734","DOI":"10.1002\/ppul.26823","article-title":"Impact of elexacaftor\/tezacaftor\/ivacaftor on lipid and fat-soluble vitamin levels and association with body mass index","volume":"59","author":"Patel","year":"2024","journal-title":"Pediatr Pulmonol"},{"issue":"23","key":"10.1016\/j.jcte.2025.100391_b0070","doi-asserted-by":"crossref","DOI":"10.3390\/jcm11236900","article-title":"Cystic fibrosis patients with F508del\/minimal function genotype: laboratory and nutritional evaluations after one year of elexacaftor\/tezacaftor\/ivacaftor treatment","volume":"11","author":"Carnovale","year":"2022","journal-title":"J Clin Med"},{"issue":"11","key":"10.1016\/j.jcte.2025.100391_b0095","doi-asserted-by":"crossref","DOI":"10.1161\/JAHA.122.028892","article-title":"Evolving management of low-density lipoprotein cholesterol: a personalized approach to preventing atherosclerotic cardiovascular disease across the risk continuum","volume":"12","author":"Wilkinson","year":"2023","journal-title":"J Am Heart Assoc"},{"issue":"3","key":"10.1016\/j.jcte.2025.100391_b0100","doi-asserted-by":"crossref","first-page":"267","DOI":"10.1016\/S1567-5688(11)70885-6","article-title":"HDL-C: role as a risk modifier","volume":"12","author":"Barter","year":"2011","journal-title":"Atheroscler Suppl"},{"issue":"4","key":"10.1016\/j.jcte.2025.100391_b0105","doi-asserted-by":"crossref","first-page":"566","DOI":"10.1016\/j.jcf.2019.04.001","article-title":"Cystic fibrosis dyslipidaemia: a cross-sectional study","volume":"18","author":"Nowak","year":"2019","journal-title":"J Cyst Fibros"},{"issue":"3","key":"10.1016\/j.jcte.2025.100391_b0110","doi-asserted-by":"crossref","first-page":"410","DOI":"10.1016\/j.jcf.2017.02.010","article-title":"Dietary intake and lipid profile in children and adolescents with cystic fibrosis","volume":"16","author":"Woestenenk","year":"2017","journal-title":"J Cyst Fibros"},{"issue":"8","key":"10.1016\/j.jcte.2025.100391_b0115","doi-asserted-by":"crossref","first-page":"835","DOI":"10.1136\/thorax-2022-219943","article-title":"Effect of elexacaftor\/tezacaftor\/ivacaftor on airway and systemic inflammation in cystic fibrosis","volume":"78","author":"Casey","year":"2023","journal-title":"Thorax"},{"issue":"2","key":"10.1016\/j.jcte.2025.100391_b0120","doi-asserted-by":"crossref","first-page":"265","DOI":"10.1016\/j.jcf.2021.11.012","article-title":"Effect of elexacaftor-tezacaftor-ivacaftor on body weight and metabolic parameters in adults with cystic fibrosis","volume":"21","author":"Petersen","year":"2022","journal-title":"J Cyst Fibros"},{"issue":"6","key":"10.1016\/j.jcte.2025.100391_b0125","doi-asserted-by":"crossref","first-page":"1024","DOI":"10.1016\/j.jcf.2023.10.002","article-title":"Alterations in lipids after initiation of highly effective modulators in people with cystic fibrosis","volume":"22","author":"Despotes","year":"2023","journal-title":"J Cyst Fibros"},{"issue":"6","key":"10.1016\/j.jcte.2025.100391_b0060","doi-asserted-by":"crossref","first-page":"1027","DOI":"10.1016\/j.jcf.2023.07.001","article-title":"Improvement of lipid and lipoprotein profiles in children and adolescents with cystic fibrosis on CFTR modulator therapy","volume":"22","author":"Yuzyuk","year":"2023","journal-title":"J Cyst Fibros"},{"key":"10.1016\/j.jcte.2025.100391_b0130","unstructured":"Levy et al. 1993 - Circulating Tumor Necrosis Factor-\u03b1 Levels and Lip.pdf."},{"issue":"9","key":"10.1016\/j.jcte.2025.100391_b0135","doi-asserted-by":"crossref","first-page":"960","DOI":"10.1016\/j.jacc.2021.06.011","article-title":"2021 ACC expert consensus decision pathway on the management of ASCVD risk reduction in patients with persistent hypertriglyceridemia: a report of the American College of Cardiology Solution Set Oversight Committee","volume":"78","author":"Virani","year":"2021","journal-title":"J Am Coll Cardiol"},{"issue":"2","key":"10.1016\/j.jcte.2025.100391_b0140","doi-asserted-by":"crossref","first-page":"153","DOI":"10.1016\/j.jacc.2022.11.013","article-title":"Triglyceride-rich lipoproteins and atherosclerotic cardiovascular diseaserisk","volume":"81","author":"Duell","year":"2023","journal-title":"J Am Coll Cardiol"},{"key":"10.1016\/j.jcte.2025.100391_b0145","doi-asserted-by":"crossref","unstructured":"Expert Panel on Integrated Guidelines for Cardiovascular, H., et al., Expert panel on integrated guidelines for cardiovascular health and risk reduction in children and adolescents: summary report. Pediatrics, 2011. 128 Suppl 5(Suppl 5): p. S213-56.","DOI":"10.1542\/peds.2009-2107C"},{"issue":"8","key":"10.1016\/j.jcte.2025.100391_b0150","doi-asserted-by":"crossref","first-page":"1591","DOI":"10.1016\/j.jand.2020.03.015","article-title":"Academy of nutrition and dietetics: 2020 cystic fibrosis evidence analysis center evidence-based nutrition practice guideline","volume":"121","author":"McDonald","year":"2021","journal-title":"J Acad Nutr Diet"},{"issue":"2","key":"10.1016\/j.jcte.2025.100391_b0155","doi-asserted-by":"crossref","DOI":"10.3390\/metabo13020253","article-title":"High-density lipoprotein alterations in type 2 diabetes and obesity","volume":"13","author":"Denimal","year":"2023","journal-title":"Metabolites"},{"issue":"9","key":"10.1016\/j.jcte.2025.100391_b0160","doi-asserted-by":"crossref","first-page":"2910","DOI":"10.1016\/j.clnu.2019.12.029","article-title":"Overweight, obesity and significant weight gain in adult patients with cystic fibrosis association with lung function and cardiometabolic risk factors","volume":"39","author":"Bonhoure","year":"2020","journal-title":"Clin Nutr"},{"key":"10.1016\/j.jcte.2025.100391_b0170","article-title":"Comparison of dietary macronutrient patterns of 14 popular named dietary programmes for weight and cardiovascular risk factor reduction in adults: systematic review and network meta-analysis of randomised trials","volume":"369","author":"Ge","year":"2020","journal-title":"BMJ"},{"key":"10.1016\/j.jcte.2025.100391_b0175","article-title":"Association of race and ethnicity with the development of cystic fibrosis-related diabetes","author":"Rayas","year":"2024","journal-title":"J Cyst Fibros"},{"issue":"1","key":"10.1016\/j.jcte.2025.100391_b0180","doi-asserted-by":"crossref","first-page":"21365","DOI":"10.1038\/s41598-020-78478-w","article-title":"Novel plasma biomarkers improve discrimination of metabolic health independent of weight","volume":"10","author":"Ellison","year":"2020","journal-title":"Sci Rep"}],"container-title":["Journal of Clinical & Translational Endocrinology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2214623725000092?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2214623725000092?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,5,31]],"date-time":"2025-05-31T19:25:52Z","timestamp":1748719552000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S2214623725000092"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,6]]},"references-count":35,"alternative-id":["S2214623725000092"],"URL":"https:\/\/doi.org\/10.1016\/j.jcte.2025.100391","relation":{},"ISSN":["2214-6237"],"issn-type":[{"value":"2214-6237","type":"print"}],"subject":[],"published":{"date-parts":[[2025,6]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Cholesterol and triglyceride concentrations following 12\u201318\u00a0months of clinically prescribed elexacaftor-tezacaftor-ivacaftor\u2014PROMISE sub-study","name":"articletitle","label":"Article Title"},{"value":"Journal of Clinical & Translational Endocrinology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.jcte.2025.100391","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2025 The Authors. Published by Elsevier Inc.","name":"copyright","label":"Copyright"}],"article-number":"100391"}}