{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,17]],"date-time":"2026-08-17T18:39:19Z","timestamp":1786991959467,"version":"build-2736575974"},"reference-count":51,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2025,12,1]],"date-time":"2025-12-01T00:00:00Z","timestamp":1764547200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2025,12,1]],"date-time":"2025-12-01T00:00:00Z","timestamp":1764547200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2025,10,27]],"date-time":"2025-10-27T00:00:00Z","timestamp":1761523200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/100000002","name":"National Institutes of Health","doi-asserted-by":"publisher","award":["AR075773"],"award-info":[{"award-number":["AR075773"]}],"id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000002","name":"National Institutes of Health","doi-asserted-by":"publisher","award":["P30 DK056341"],"award-info":[{"award-number":["P30 DK056341"]}],"id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100007930","name":"Institute of Clinical and Translational Sciences","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100007930","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100016220","name":"Georgia Clinical and Translational Science Alliance","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100016220","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100006108","name":"National Center for Advancing Translational Sciences","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100006108","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000009","name":"Foundation for the National Institutes of Health","doi-asserted-by":"publisher","award":["UL1TR002345"],"award-info":[{"award-number":["UL1TR002345"]}],"id":[{"id":"10.13039\/100000009","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","jctejournal.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Journal of Clinical & Translational Endocrinology"],"published-print":{"date-parts":[[2025,12]]},"DOI":"10.1016\/j.jcte.2025.100422","type":"journal-article","created":{"date-parts":[[2025,10,29]],"date-time":"2025-10-29T00:26:28Z","timestamp":1761697588000},"page":"100422","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":1,"special_numbering":"C","title":["Insights into intramuscular adipose\u2013muscle signaling in the diabetic lower extremity"],"prefix":"10.1016","volume":"42","author":[{"given":"Chang","family":"Gui","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dakota R.","family":"Kamm","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jeremie L.A.","family":"Ferey","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kathryn L.","family":"Bohnert","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jeremy J.","family":"McCormick","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mary K.","family":"Hastings","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9268-3993","authenticated-orcid":false,"given":"Gretchen A.","family":"Meyer","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"issue":"5","key":"10.1016\/j.jcte.2025.100422_b0005","doi-asserted-by":"crossref","first-page":"536","DOI":"10.1177\/1071100720907035","article-title":"Skeletal muscle regeneration in advanced diabetic peripheral neuropathy","volume":"41","author":"Bohnert","year":"2020","journal-title":"Foot Ankle Int"},{"issue":"4","key":"10.1016\/j.jcte.2025.100422_b0010","doi-asserted-by":"crossref","first-page":"895","DOI":"10.2337\/diacare.29.04.06.dc05-1854","article-title":"Altered fiber distribution and fiber-specific glycolytic and oxidative enzyme activity in skeletal muscle of patients with type 2 diabetes","volume":"29","author":"Oberbach","year":"2006","journal-title":"Diabetes Care"},{"issue":"5","key":"10.1016\/j.jcte.2025.100422_b0015","doi-asserted-by":"crossref","first-page":"382","DOI":"10.2337\/diacare.17.5.382","article-title":"Muscle fiber composition and capillary density in women and men with NIDDM","volume":"17","author":"M\u00e5rin","year":"1994","journal-title":"Diabetes Care"},{"issue":"8","key":"10.1016\/j.jcte.2025.100422_b0020","doi-asserted-by":"crossref","first-page":"1672","DOI":"10.2337\/dc11-2202","article-title":"Role of muscle mass and muscle quality in the association between diabetes and gait speed","volume":"35","author":"Volpato","year":"2012","journal-title":"Diabetes Care"},{"issue":"1","key":"10.1016\/j.jcte.2025.100422_b0025","doi-asserted-by":"crossref","first-page":"188","DOI":"10.2337\/db15-0647","article-title":"Obesity impairs skeletal muscle regeneration through inhibition of AMPK","volume":"65","author":"Fu","year":"2016","journal-title":"Diabetes"},{"issue":"8","key":"10.1016\/j.jcte.2025.100422_b0030","doi-asserted-by":"crossref","DOI":"10.14814\/phy2.12506","article-title":"Diet-induced obesity impairs muscle satellite cell activation and muscle repair through alterations in hepatocyte growth factor signaling","volume":"3","author":"D'Souza","year":"2015","journal-title":"Physiol Rep"},{"issue":"1","key":"10.1016\/j.jcte.2025.100422_b0035","doi-asserted-by":"crossref","first-page":"46","DOI":"10.1111\/apha.12537","article-title":"Diet-induced obesity alters anabolic signalling in mice at the onset of skeletal muscle regeneration","volume":"215","author":"Brown","year":"2015","journal-title":"Acta Physiol (Oxf)"},{"issue":"6","key":"10.1016\/j.jcte.2025.100422_b0040","doi-asserted-by":"crossref","first-page":"1204","DOI":"10.1016\/j.cmet.2024.02.014","article-title":"Impaired skeletal muscle regeneration in diabetes: from cellular and molecular mechanisms to novel treatments","volume":"36","author":"Espino-Gonzalez","year":"2024","journal-title":"Cell Metab"},{"issue":"1","key":"10.1016\/j.jcte.2025.100422_b0045","doi-asserted-by":"crossref","first-page":"15360","DOI":"10.1038\/s41598-018-33840-x","article-title":"Obese subcutaneous adipose tissue impairs human myogenesis, particularly in old skeletal muscle, via resistin-mediated activation of NF\u03baB","volume":"8","author":"O'Leary","year":"2018","journal-title":"Sci Rep"},{"issue":"5","key":"10.1016\/j.jcte.2025.100422_b0050","doi-asserted-by":"crossref","first-page":"285","DOI":"10.1038\/s41574-022-00784-2","article-title":"Intermuscular adipose tissue in metabolic disease","volume":"19","author":"Goodpaster","year":"2023","journal-title":"Nat Rev Endocrinol"},{"issue":"16","key":"10.1016\/j.jcte.2025.100422_b0055","doi-asserted-by":"crossref","DOI":"10.14814\/phy2.15424","article-title":"Quantifying the inflammatory secretome of human intermuscular adipose tissue","volume":"10","author":"Kahn","year":"2022","journal-title":"Physiol Rep"},{"issue":"1","key":"10.1016\/j.jcte.2025.100422_b0060","doi-asserted-by":"crossref","first-page":"16422","DOI":"10.1038\/s41598-024-67152-0","article-title":"Mature adipocytes inhibit differentiation of myogenic cells but stimulate proliferation of fibro-adipogenic precursors derived from trout muscle in vitro","volume":"14","author":"Goffette","year":"2024","journal-title":"Sci Rep"},{"issue":"3","key":"10.1016\/j.jcte.2025.100422_b0065","doi-asserted-by":"crossref","first-page":"423","DOI":"10.1111\/asj.13145","article-title":"Adipocytes suppress differentiation of muscle cells in a co-culture system","volume":"90","author":"Seo","year":"2019","journal-title":"Anim Sci J"},{"issue":"7","key":"10.1016\/j.jcte.2025.100422_b0070","doi-asserted-by":"crossref","first-page":"1023","DOI":"10.1038\/s41587-021-01156-3","article-title":"SignalP 6.0 predicts all five types of signal peptides using protein language models","volume":"40","author":"Teufel","year":"2022","journal-title":"Nat Biotechnol"},{"issue":"7","key":"10.1016\/j.jcte.2025.100422_b0075","doi-asserted-by":"crossref","first-page":"764","DOI":"10.5966\/sctm.2014-0287","article-title":"Epimuscular fat in the human rotator cuff is a novel beige depot","volume":"4","author":"Meyer","year":"2015","journal-title":"Stem Cells Transl Med"},{"issue":"11","key":"10.1016\/j.jcte.2025.100422_b0080","doi-asserted-by":"crossref","first-page":"2457","DOI":"10.2337\/dbi19-0006","article-title":"The metabolic significance of intermuscular adipose tissue: is IMAT a friend or a foe to metabolic health?","volume":"70","author":"Sparks","year":"2021","journal-title":"Diabetes"},{"issue":"12","key":"10.1016\/j.jcte.2025.100422_b0085","doi-asserted-by":"crossref","first-page":"2247","DOI":"10.2337\/db19-0560","article-title":"subcutaneous adipose tissue and systemic inflammation are associated with peripheral but not hepatic insulin resistance in humans","volume":"68","author":"van der Kolk","year":"2019","journal-title":"Diabetes"},{"issue":"3","key":"10.1016\/j.jcte.2025.100422_b0090","doi-asserted-by":"crossref","first-page":"1019","DOI":"10.2337\/db10-1270","article-title":"Global gene expression profiles of subcutaneous adipose and muscle from glucose-tolerant, insulin-sensitive, and insulin-resistant individuals matched for BMI","volume":"60","author":"Elbein","year":"2011","journal-title":"Diabetes"},{"issue":"5","key":"10.1016\/j.jcte.2025.100422_b0095","doi-asserted-by":"crossref","first-page":"E866","DOI":"10.1152\/ajpendo.00243.2018","article-title":"Intermuscular adipose tissue directly modulates skeletal muscle insulin sensitivity in humans","volume":"316","author":"Sachs","year":"2019","journal-title":"Am J Phys Endocrinol Metab"},{"key":"10.1016\/j.jcte.2025.100422_b0100","article-title":"The markers to delineate different phenotypes of macrophages related to metabolic disorders","volume":"14","author":"Wei","year":"2023","journal-title":"Front Immunol"},{"issue":"18","key":"10.1016\/j.jcte.2025.100422_b0105","doi-asserted-by":"crossref","DOI":"10.3390\/cells11182879","article-title":"Dectin-1 as a potential inflammatory biomarker for metabolic inflammation in adipose tissue of individuals with obesity","volume":"11","author":"Al Madhoun","year":"2022","journal-title":"Cells"},{"issue":"11","key":"10.1016\/j.jcte.2025.100422_b0110","doi-asserted-by":"crossref","DOI":"10.1084\/jem.20191847","article-title":"Macrophage morphology correlates with single-cell diversity and prognosis in colorectal liver metastasis","volume":"217","author":"Donadon","year":"2020","journal-title":"J Exp Med"},{"issue":"Pt 15","key":"10.1016\/j.jcte.2025.100422_b0115","doi-asserted-by":"crossref","first-page":"3531","DOI":"10.1242\/jcs.02482","article-title":"Improved muscle healing through enhanced regeneration and reduced fibrosis in myostatin-null mice","volume":"118","author":"McCroskery","year":"2005","journal-title":"J Cell Sci"},{"key":"10.1016\/j.jcte.2025.100422_b0120","doi-asserted-by":"crossref","first-page":"14","DOI":"10.1186\/s13395-015-0038-6","article-title":"Wnt\/\u03b2-catenin controls follistatin signalling to regulate satellite cell myogenic potential","volume":"5","author":"Jones","year":"2015","journal-title":"Skelet Muscle"},{"issue":"2","key":"10.1016\/j.jcte.2025.100422_b0125","doi-asserted-by":"crossref","first-page":"279","DOI":"10.1007\/s11154-023-09850-0","article-title":"An update on the secretory functions of brown, white, and beige adipose tissue: Towards therapeutic applications","volume":"25","author":"Ghesmati","year":"2024","journal-title":"Rev Endocr Metab Disord"},{"issue":"9","key":"10.1016\/j.jcte.2025.100422_b0130","doi-asserted-by":"crossref","first-page":"2425","DOI":"10.1634\/stemcells.2008-0325","article-title":"A reservoir of brown adipocyte progenitors in human skeletal muscle","volume":"26","author":"Crisan","year":"2008","journal-title":"Stem Cells"},{"key":"10.1016\/j.jcte.2025.100422_b0135","doi-asserted-by":"crossref","DOI":"10.1155\/2014\/309570","article-title":"Intermuscular fat: a review of the consequences and causes","volume":"2014","author":"Addison","year":"2014","journal-title":"Int J Endocrinol"},{"issue":"3","key":"10.1016\/j.jcte.2025.100422_b0140","doi-asserted-by":"crossref","first-page":"497","DOI":"10.1038\/ijo.2015.193","article-title":"Adipogenic progenitors from obese human skeletal muscle give rise to functional white adipocytes that contribute to insulin resistance","volume":"40","author":"Laurens","year":"2016","journal-title":"Int J Obes (Lond)"},{"issue":"5","key":"10.1016\/j.jcte.2025.100422_b0145","doi-asserted-by":"crossref","first-page":"873","DOI":"10.1007\/s00125-023-05874-y","article-title":"Skeletal muscle and intermuscular adipose tissue gene expression profiling identifies new biomarkers with prognostic significance for insulin resistance progression and intervention response","volume":"66","author":"Lutter","year":"2023","journal-title":"Diabetologia"},{"issue":"3","key":"10.1016\/j.jcte.2025.100422_b0150","doi-asserted-by":"crossref","first-page":"228","DOI":"10.1111\/age.12781","article-title":"Genome-wide identification and comparison of mRNAs, lncRNAs and circRNAs in porcine intramuscular, subcutaneous, retroperitoneal and mesenteric adipose tissues","volume":"50","author":"Liu","year":"2019","journal-title":"Anim Genet"},{"issue":"2","key":"10.1016\/j.jcte.2025.100422_b0155","doi-asserted-by":"crossref","first-page":"213","DOI":"10.1016\/j.meatsci.2011.01.003","article-title":"A review of the factors influencing the development of intermuscular adipose tissue in the growing pig","volume":"88","author":"Kouba","year":"2011","journal-title":"Meat Sci"},{"issue":"1","key":"10.1016\/j.jcte.2025.100422_b0160","doi-asserted-by":"crossref","first-page":"125","DOI":"10.1042\/CBI20090046","article-title":"Comparison of gene expression profiling between bovine subcutaneous and intramuscular adipose tissues by serial analysis of gene expression","volume":"34","author":"Bong","year":"2009","journal-title":"Cell Biol Int"},{"issue":"6","key":"10.1016\/j.jcte.2025.100422_b0165","doi-asserted-by":"crossref","first-page":"831","DOI":"10.7150\/ijbs.4493","article-title":"Co-methylated genes in different adipose depots of pig are associated with metabolic, inflammatory and immune processes","volume":"8","author":"Li","year":"2012","journal-title":"Int J Biol Sci"},{"key":"10.1016\/j.jcte.2025.100422_b0170","doi-asserted-by":"crossref","first-page":"75","DOI":"10.1186\/1476-511X-12-75","article-title":"Gene expression profiling reveals distinct features of various porcine adipose tissues","volume":"12","author":"Zhou","year":"2013","journal-title":"Lipids Health Dis"},{"issue":"10","key":"10.1016\/j.jcte.2025.100422_b0175","doi-asserted-by":"crossref","first-page":"1495","DOI":"10.1292\/jvms.18-0324","article-title":"Fat depot-specific differences of macrophage infiltration and cellular senescence in obese bovine adipose tissues","volume":"80","author":"Yamada","year":"2018","journal-title":"J Vet Med Sci"},{"issue":"6","key":"10.1016\/j.jcte.2025.100422_b0180","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0066267","article-title":"Comparative transcriptome analysis of adipose tissues reveals that ECM-receptor interaction is involved in the depot-specific adipogenesis in cattle","volume":"8","author":"Lee","year":"2013","journal-title":"PLoS One"},{"issue":"7","key":"10.1016\/j.jcte.2025.100422_b0185","article-title":"Transcriptome and cellular evidence of depot-specific function in beef cattle intramuscular, subcutaneous, and visceral adipose tissues","volume":"14","author":"Tegeler","year":"2025","journal-title":"Biology (Basel)"},{"issue":"3","key":"10.1016\/j.jcte.2025.100422_b0190","doi-asserted-by":"crossref","first-page":"190","DOI":"10.2106\/JBJS.16.00335","article-title":"Histological evidence of muscle degeneration in advanced human rotator cuff disease","volume":"99","author":"Gibbons","year":"2017","journal-title":"J Bone Joint Surg Am"},{"issue":"1","key":"10.1016\/j.jcte.2025.100422_b0195","doi-asserted-by":"crossref","first-page":"630","DOI":"10.1080\/21623945.2022.2148886","article-title":"Associations of GHR, IGF-1 and IGFBP-3 expression in adipose tissue cells with obesity-related alterations in corresponding circulating levels and adipose tissue function in children","volume":"11","author":"Kempf","year":"2022","journal-title":"Adipocyte"},{"issue":"5","key":"10.1016\/j.jcte.2025.100422_b0200","doi-asserted-by":"crossref","first-page":"E918","DOI":"10.1152\/ajpendo.00798.2007","article-title":"Myostatin, activin receptor IIb, and follistatin-like-3 gene expression are altered in adipose tissue and skeletal muscle of obese mice","volume":"294","author":"Allen","year":"2008","journal-title":"American J Physiol \u2013Endocrinol Metab"},{"issue":"7","key":"10.1016\/j.jcte.2025.100422_b0205","doi-asserted-by":"crossref","first-page":"2776","DOI":"10.1210\/jc.2005-2848","article-title":"Acquired obesity increases CD68 and tumor necrosis factor-alpha and decreases adiponectin gene expression in adipose tissue: a study in monozygotic twins","volume":"91","author":"Pietil\u00e4inen","year":"2006","journal-title":"J Clin Endocrinol Metab"},{"issue":"1","key":"10.1016\/j.jcte.2025.100422_b0210","doi-asserted-by":"crossref","first-page":"109","DOI":"10.1002\/jcsm.12643","article-title":"Single-cell RNA sequencing and lipidomics reveal cell and lipid dynamics of fat infiltration in skeletal muscle","volume":"12","author":"Xu","year":"2021","journal-title":"J Cachexia Sarcopenia Muscle"},{"key":"10.1016\/j.jcte.2025.100422_b0215","doi-asserted-by":"crossref","first-page":"1525","DOI":"10.1100\/tsw.2011.137","article-title":"Impaired muscle regeneration in ob\/ob and db\/db mice","volume":"11","author":"Nguyen","year":"2011","journal-title":"ScientificWorldJournal"},{"issue":"8","key":"10.1016\/j.jcte.2025.100422_b0220","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0070971","article-title":"Impaired macrophage and satellite cell infiltration occurs in a muscle-specific fashion following injury in diabetic skeletal muscle","volume":"8","author":"Krause","year":"2013","journal-title":"PLoS One"},{"issue":"8","key":"10.1016\/j.jcte.2025.100422_b0225","doi-asserted-by":"crossref","first-page":"1052","DOI":"10.1038\/aps.2013.67","article-title":"Pharmacological inhibition of myostatin\/TGF-\u03b2 receptor\/pSmad3 signaling rescues muscle regenerative responses in mouse model of type 1 diabetes","volume":"34","author":"Jeong","year":"2013","journal-title":"Acta Pharmacol Sin"},{"issue":"1","key":"10.1016\/j.jcte.2025.100422_b0230","doi-asserted-by":"crossref","first-page":"161","DOI":"10.1016\/j.scr.2016.06.007","article-title":"Pharmacological blockage of fibro\/adipogenic progenitor expansion and suppression of regenerative fibrogenesis is associated with impaired skeletal muscle regeneration","volume":"17","author":"Fiore","year":"2016","journal-title":"Stem Cell Res"},{"issue":"2","key":"10.1016\/j.jcte.2025.100422_b0235","doi-asserted-by":"crossref","first-page":"153","DOI":"10.1038\/ncb2015","article-title":"Muscle injury activates resident fibro\/adipogenic progenitors that facilitate myogenesis","volume":"12","author":"Joe","year":"2010","journal-title":"Nat Cell Biol"},{"issue":"2","key":"10.1016\/j.jcte.2025.100422_b0240","doi-asserted-by":"crossref","first-page":"384","DOI":"10.1002\/jcsm.12277","article-title":"Uncoupling protein 1 expression in adipocytes derived from skeletal muscle fibro\/adipogenic progenitors is under genetic and hormonal control","volume":"9","author":"Gorski","year":"2018","journal-title":"J Cachexia Sarcopenia Muscle"},{"issue":"7","key":"10.1016\/j.jcte.2025.100422_b0245","doi-asserted-by":"crossref","first-page":"2366","DOI":"10.1073\/pnas.0610416104","article-title":"Ectopic brown adipose tissue in muscle provides a mechanism for differences in risk of metabolic syndrome in mice","volume":"104","author":"Almind","year":"2007","journal-title":"PNAS"},{"issue":"12","key":"10.1016\/j.jcte.2025.100422_b0250","doi-asserted-by":"crossref","first-page":"2599","DOI":"10.1002\/jor.25627","article-title":"Development and expansion of intramuscular adipose tissue is not dependent on UCP-1-lineage cells in mice","volume":"41","author":"Parson","year":"2023","journal-title":"J Orthop Res"},{"issue":"9\u201310","key":"10.1016\/j.jcte.2025.100422_b0255","doi-asserted-by":"crossref","first-page":"1055","DOI":"10.1016\/j.clinbiomech.2013.10.006","article-title":"Intrinsic foot muscle deterioration is associated with metatarsophalangeal joint angle in people with diabetes and neuropathy","volume":"28","author":"Cheuy","year":"2013","journal-title":"Clin Biomech (Bristol)"}],"container-title":["Journal of Clinical & Translational Endocrinology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2214623725000407?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2214623725000407?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,12,19]],"date-time":"2025-12-19T16:56:33Z","timestamp":1766163393000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S2214623725000407"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,12]]},"references-count":51,"alternative-id":["S2214623725000407"],"URL":"https:\/\/doi.org\/10.1016\/j.jcte.2025.100422","relation":{},"ISSN":["2214-6237"],"issn-type":[{"value":"2214-6237","type":"print"}],"subject":[],"published":{"date-parts":[[2025,12]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Insights into intramuscular adipose\u2013muscle signaling in the diabetic lower extremity","name":"articletitle","label":"Article Title"},{"value":"Journal of Clinical & Translational Endocrinology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.jcte.2025.100422","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2025 The Authors. Published by Elsevier Inc.","name":"copyright","label":"Copyright"}],"article-number":"100422"}}