{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,13]],"date-time":"2026-07-13T12:54:24Z","timestamp":1783947264703,"version":"3.55.0"},"reference-count":43,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2022,12,1]],"date-time":"2022-12-01T00:00:00Z","timestamp":1669852800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2022,12,1]],"date-time":"2022-12-01T00:00:00Z","timestamp":1669852800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2022,11,7]],"date-time":"2022-11-07T00:00:00Z","timestamp":1667779200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100021567","name":"Debre Markos University","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100021567","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Journal of Clinical Tuberculosis and Other Mycobacterial Diseases"],"published-print":{"date-parts":[[2022,12]]},"DOI":"10.1016\/j.jctube.2022.100336","type":"journal-article","created":{"date-parts":[[2022,11,10]],"date-time":"2022-11-10T04:12:47Z","timestamp":1668053567000},"page":"100336","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":10,"special_numbering":"C","title":["Prevalence, associated factors and rifampicin resistance pattern of pulmonary tuberculosis among HIV-positive patients attending antiretroviral treatment clinic at East Gojjam Zone, Ethiopia: An institution-based cross-sectional study"],"prefix":"10.1016","volume":"29","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-8278-0343","authenticated-orcid":false,"given":"Milkiyas","family":"Toru","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Amanuel","family":"Baye","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zemenu","family":"Gebeyehu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8132-4001","authenticated-orcid":false,"given":"Abtie","family":"Abebaw","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5086-0776","authenticated-orcid":false,"given":"Alemayehu","family":"Reta","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"issue":"4","key":"10.1016\/j.jctube.2022.100336_b0005","doi-asserted-by":"crossref","first-page":"202","DOI":"10.1038\/nrmicro.2018.8","article-title":"Ecology and evolution of Mycobacterium tuberculosis","volume":"16","author":"Gagneux","year":"2018","journal-title":"Nat Rev Microbiol"},{"key":"10.1016\/j.jctube.2022.100336_b0010","unstructured":"Murray R, Rosenthal K: PM. Medical microbiology 8th edition. In.: Elsevier; 2016."},{"key":"10.1016\/j.jctube.2022.100336_b0015","unstructured":"World Health Organization. (2018). Global tuberculosis report 2018. World Health Organization. https:\/\/apps.who.int\/iris\/handle\/10665\/27445License: CC BY-NC-SA 3.0 IGO."},{"key":"10.1016\/j.jctube.2022.100336_b0020","unstructured":"World Health Organization: The use of delamanid in the treatment of multidrug-resistant tuberculosis in children and adolescents: interim policy guidance. 2016."},{"issue":"11","key":"10.1016\/j.jctube.2022.100336_b0025","doi-asserted-by":"crossref","first-page":"263","DOI":"10.15585\/mmwr.mm6811a3","article-title":"Global epidemiology of tuberculosis and progress toward achieving global targets\u20142017","volume":"68","author":"MacNeil","year":"2019","journal-title":"Morb Mortal Wkly Rep"},{"key":"10.1016\/j.jctube.2022.100336_b0030","unstructured":"Nuttbrock S: Country Health System Overview: Ethiopia."},{"key":"10.1016\/j.jctube.2022.100336_b0035","series-title":"Global Tuberculosis Report 2019","first-page":"7","author":"Annabel","year":"2019"},{"key":"10.1016\/j.jctube.2022.100336_b0040","doi-asserted-by":"crossref","first-page":"163","DOI":"10.2174\/1874285801812010163","article-title":"Prevalence of pulmonary tuberculosis and associated factors among HIV positive patients attending antiretroviral therapy clinic at Arba minch general hospital, Southern Ethiopia","volume":"12","author":"Mama","year":"2018","journal-title":"Open Microbiol J"},{"issue":"2","key":"10.1016\/j.jctube.2022.100336_b0045","first-page":"588","article-title":"Prevalence and associated factors of TB\/HIV co-infection among HIV Infected patients in Amhara region, Ethiopia","volume":"16","author":"Mitku","year":"2016","journal-title":"Afr Health Sci"},{"issue":"1","key":"10.1016\/j.jctube.2022.100336_b0050","doi-asserted-by":"crossref","first-page":"15","DOI":"10.4103\/JNMS.JNMS_50_18","article-title":"Tuberculosis and HIV Co-infection and associated factors among HIV reactive patients in Ethiopia","volume":"6","author":"Fite","year":"2019","journal-title":"J Nurs Midwifery Sci"},{"issue":"1","key":"10.1016\/j.jctube.2022.100336_b0055","doi-asserted-by":"crossref","first-page":"1091","DOI":"10.1186\/s12889-016-3761-y","article-title":"Smear positive pulmonary tuberculosis and HIV co-infection in prison settings of North Gondar Zone, Northwest Ethiopia","volume":"16","author":"Gebrecherkos","year":"2016","journal-title":"BMC Public Health"},{"issue":"1","key":"10.1016\/j.jctube.2022.100336_b0060","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1186\/1756-0500-5-331","article-title":"Prevalence of pulmonary tuberculosis and immunological profile of HIV co-infected patients in Northwest Ethiopia","volume":"5","author":"Wondimeneh","year":"2012","journal-title":"BMC Res Notes"},{"key":"10.1016\/j.jctube.2022.100336_b0065","series-title":"Xpert MTB\/RIF Implementation Manual: Technical and Operational \u2018how-to\u2019; Practical Considerations","author":"Organization","year":"2014"},{"issue":"10","key":"10.1016\/j.jctube.2022.100336_b0070","doi-asserted-by":"crossref","first-page":"1076","DOI":"10.15537\/smj.2016.10.14998","article-title":"Evaluation of GeneXpert MTB\/RIF assay for direct diagnosis of pulmonary tuberculosis","volume":"37","author":"Moussa","year":"2016","journal-title":"Saudi Med J"},{"issue":"6","key":"10.1016\/j.jctube.2022.100336_b0075","doi-asserted-by":"crossref","first-page":"e20458","DOI":"10.1371\/journal.pone.0020458","article-title":"Rapid and accurate detection of Mycobacterium tuberculosis in sputum samples by Cepheid Xpert MTB\/RIF assay \u2013 A clinical validation study","volume":"6","author":"Rachow","year":"2011","journal-title":"PLoS One"},{"issue":"Suppl 1","key":"10.1016\/j.jctube.2022.100336_b0080","doi-asserted-by":"crossref","first-page":"S27","DOI":"10.1086\/650390","article-title":"Laboratory operations, specimen processing, and handling for viral load testing and surveillance","volume":"201","author":"Puren","year":"2010","journal-title":"J Infect Dis"},{"key":"10.1016\/j.jctube.2022.100336_b0085","unstructured":"Organization WH: Protocol for the laboratory evaluation of nucleic acid based HIV viral load testing technologies. 2017."},{"issue":"9829","key":"10.1016\/j.jctube.2022.100336_b0090","doi-asserted-by":"crossref","first-page":"1902","DOI":"10.1016\/S0140-6736(12)60727-2","article-title":"Scaling up interventions to achieve global tuberculosis control: progress and new developments","volume":"379","author":"Raviglione","year":"2012","journal-title":"Lancet"},{"issue":"1","key":"10.1016\/j.jctube.2022.100336_b0095","doi-asserted-by":"crossref","first-page":"676","DOI":"10.1186\/s12879-018-3604-9","article-title":"Tuberculosis-human immunodeficiency virus (HIV) co-infection in Ethiopia: A systematic review and meta-analysis","volume":"18","author":"Teweldemedhin","year":"2018","journal-title":"BMC Infect Dis"},{"issue":"9","key":"10.1016\/j.jctube.2022.100336_b0100","doi-asserted-by":"crossref","first-page":"1181","DOI":"10.1111\/tmi.12749","article-title":"Tuberculosis and non-tuberculous mycobacteria among HIV-infected individuals in Ghana","volume":"21","author":"Bjerrum","year":"2016","journal-title":"Trop Med Int Health"},{"issue":"3","key":"10.1016\/j.jctube.2022.100336_b0105","doi-asserted-by":"crossref","first-page":"289","DOI":"10.1080\/15321819.2019.1583579","article-title":"Rifampicin-Resistant tuberculosis among known HIV-infected patients in Oyo state, Nigeria","volume":"40","author":"Adetunji","year":"2019","journal-title":"J Immunoassay Immunochem"},{"key":"10.1016\/j.jctube.2022.100336_b0110","doi-asserted-by":"crossref","first-page":"1346104","DOI":"10.1155\/2018\/1346104","article-title":"Prevalence and risk factors of active TB among adult HIV patients receiving ART in Northwestern Tanzania: A retrospective cohort study","volume":"2018","author":"Gunda","year":"2018","journal-title":"Can J Infect Dis Med Microbiol"},{"issue":"5","key":"10.1016\/j.jctube.2022.100336_b0115","doi-asserted-by":"crossref","first-page":"358","DOI":"10.1016\/j.jiph.2013.04.004","article-title":"Prevalence of HIV infection among tuberculosis patients in Eastern India","volume":"6","author":"Manjareeka","year":"2013","journal-title":"J Infect Public Health"},{"issue":"3","key":"10.1016\/j.jctube.2022.100336_b0120","doi-asserted-by":"crossref","first-page":"e0173976","DOI":"10.1371\/journal.pone.0173976","article-title":"Risk factors associated with Tuberculosis (TB) among people living with HIV\/AIDS: A pair-matched case-control study in Guangxi, China","volume":"12","author":"Cui","year":"2017","journal-title":"PLoS One"},{"issue":"2","key":"10.1016\/j.jctube.2022.100336_b0125","doi-asserted-by":"crossref","first-page":"106","DOI":"10.1080\/20786190.2014.978105","article-title":"An assessment of the risk factors for pulmonary tuberculosis among adult patients suffering from human immunodeficiency virus attending the Wellness Clinic at Themba Hospital","volume":"57","author":"Herrera Rodriguez","year":"2015","journal-title":"South Afr Family Practice"},{"issue":"1","key":"10.1016\/j.jctube.2022.100336_b0130","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1186\/1756-0500-7-578","article-title":"Prevalence of national treatment algorithm defined smear-positive pulmonary tuberculosis in HIV positive patients in Brazzaville, Republic of Congo","volume":"7","author":"Linguissi","year":"2014","journal-title":"BMC Res Notes"},{"key":"10.1016\/j.jctube.2022.100336_b0135","doi-asserted-by":"crossref","first-page":"204","DOI":"10.11604\/pamj.2018.29.204.14579","article-title":"Prevalence of rifampicin resistance by automated Genexpert rifampicin assay in patients with pulmonary tuberculosis in Yenagoa, Nigeria","volume":"29","author":"Ikuabe","year":"2018","journal-title":"Pan Afr Med J"},{"issue":"12","key":"10.1016\/j.jctube.2022.100336_b0140","first-page":"1406","article-title":"Tuberculosis among HIV-positive patients at Butajira hospital, south-Central Ethiopia","volume":"6","author":"Mohammed","year":"2015","journal-title":"Int J Pharma Sci Res"},{"issue":"8","key":"10.1016\/j.jctube.2022.100336_b0145","doi-asserted-by":"crossref","first-page":"898","DOI":"10.3855\/jidc.5667","article-title":"Prevalence and determinants of Tuberculosis among HIV infected patients in south Ethiopia","volume":"9","author":"Fekadu","year":"2015","journal-title":"J Infect Dev Ctries"},{"issue":"4","key":"10.1016\/j.jctube.2022.100336_b0150","first-page":"86","article-title":"HIV and TB co-infection in South Sudan: A three year retrospective study","volume":"7","author":"Sube","year":"2014","journal-title":"South Sudan Med J"},{"key":"10.1016\/j.jctube.2022.100336_b0155","unstructured":"Iroha U, Osueke A, Ezeribe C, Nduka I, Eluwah J, Onwere S: A five year review of tuberculosis and HIV co-infection at Abia State University Teaching Hospital, Aba, Abia State, Nigeria. Abia State University Medical Students' Association Journal 2013, 8(1)."},{"key":"10.1016\/j.jctube.2022.100336_b0160","unstructured":"Isaac I, John R, Udomah F, Erhabor O: Tuberculosis and HIV\/AIDS co-infection rate among tuberculosis patients in Sokoto TB center, NorthWestern Nigeria. BJMLS, 1 (1): 40 2016, 46(40):2."},{"key":"10.1016\/j.jctube.2022.100336_b0165","doi-asserted-by":"crossref","first-page":"306","DOI":"10.3389\/fpubh.2019.00306","article-title":"Incidence rates for tuberculosis among HIV infected patients in Northern Tanzania","volume":"7","author":"Mollel","year":"2019","journal-title":"Front Public Health"},{"issue":"11","key":"10.1016\/j.jctube.2022.100336_b0170","doi-asserted-by":"crossref","first-page":"1173","DOI":"10.5588\/ijtld.17.0230","article-title":"Time to treatment for rifampicin-resistant tuberculosis: Systematic review and meta-analysis","volume":"21","author":"Boyd","year":"2017","journal-title":"Int J Tuberc Lung Dis"},{"key":"10.1016\/j.jctube.2022.100336_b0175","doi-asserted-by":"crossref","DOI":"10.1590\/s1518-8787.2017051006688","article-title":"Risk factors associated with multidrug-resistant tuberculosis in Esp\u00edrito Santo, Brazil","volume":"51","author":"Fregona","year":"2017","journal-title":"Revista de saude publica"},{"issue":"1","key":"10.1016\/j.jctube.2022.100336_b0180","doi-asserted-by":"crossref","DOI":"10.1186\/s12879-019-4375-7","article-title":"Prevalence and factors associated with multidrug\/rifampicin resistant tuberculosis among suspected drug resistant tuberculosis patients in Botswana","volume":"19","author":"Tembo","year":"2019","journal-title":"BMC Infect Dis"},{"key":"10.1016\/j.jctube.2022.100336_b0185","doi-asserted-by":"crossref","DOI":"10.11604\/pamj.2018.29.204.14579","article-title":"Prevalence of rifampicin resistance by automated Genexpert rifampicin assay in patients with pulmonary tuberculosis in Yenagoa, Nigeria","volume":"29","author":"Ikuabe","year":"2018","journal-title":"Pan Afr Med J"},{"issue":"1","key":"10.1016\/j.jctube.2022.100336_b0190","doi-asserted-by":"crossref","DOI":"10.1186\/s12879-019-3943-1","article-title":"Prevalence of rifampicin resistant Mycobacterium tuberculosis among presumptive tuberculosis patients in selected governmental hospitals in Addis Ababa, Ethiopia","volume":"19","author":"Arega","year":"2019","journal-title":"BMC Infect Dis"},{"issue":"1","key":"10.1016\/j.jctube.2022.100336_b0195","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1186\/s13104-019-4548-x","article-title":"Latent tuberculosis infection and associated risk factors among people living with HIV and apparently healthy blood donors at the University of Gondar referral hospital, Northwest Ethiopia","volume":"12","author":"Tilahun","year":"2019","journal-title":"BMC Res Notes"},{"key":"10.1016\/j.jctube.2022.100336_b0200","unstructured":"Center for Diseases Control and Prevention.Tuberculosis Risk Factors\/ Basic facts about Tuberculosis [https:\/\/www.cdc.gov\/tb\/topic\/basics\/risk.htm]."},{"issue":"1","key":"10.1016\/j.jctube.2022.100336_b0205","doi-asserted-by":"crossref","first-page":"e000247","DOI":"10.1136\/bmjresp-2017-000247","article-title":"Alcohol drinking and cigarette smoking in relation to risk of active tuberculosis: Prospective cohort study","volume":"4","author":"Soh","year":"2017","journal-title":"BMJ Open Respiratory Res"},{"issue":"1","key":"10.1016\/j.jctube.2022.100336_b0210","doi-asserted-by":"crossref","first-page":"1566","DOI":"10.1186\/s12889-019-7912-9","article-title":"Incidence and predictors of tuberculosis among HIV-positive adults on antiretroviral therapy at Debre Markos referral hospital, Northwest Ethiopia: A retrospective record review","volume":"19","author":"Temesgen","year":"2019","journal-title":"BMC Public Health"},{"issue":"10","key":"10.1016\/j.jctube.2022.100336_b0215","doi-asserted-by":"crossref","first-page":"e0203986","DOI":"10.1371\/journal.pone.0203986","article-title":"The twin epidemics: Prevalence of TB\/HIV co-infection and its associated factors in Ethiopia; A systematic review and meta-analysis","volume":"13","author":"Tesfaye","year":"2018","journal-title":"PLoS One"}],"container-title":["Journal of Clinical Tuberculosis and Other Mycobacterial Diseases"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2405579422000419?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2405579422000419?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,11,7]],"date-time":"2025-11-07T07:37:08Z","timestamp":1762501028000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S2405579422000419"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,12]]},"references-count":43,"alternative-id":["S2405579422000419"],"URL":"https:\/\/doi.org\/10.1016\/j.jctube.2022.100336","relation":{},"ISSN":["2405-5794"],"issn-type":[{"value":"2405-5794","type":"print"}],"subject":[],"published":{"date-parts":[[2022,12]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Prevalence, associated factors and rifampicin resistance pattern of pulmonary tuberculosis among HIV-positive patients attending antiretroviral treatment clinic at East Gojjam Zone, Ethiopia: An institution-based cross-sectional study","name":"articletitle","label":"Article Title"},{"value":"Journal of Clinical Tuberculosis and Other Mycobacterial Diseases","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.jctube.2022.100336","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2022 The Author(s). Published by Elsevier Ltd.","name":"copyright","label":"Copyright"}],"article-number":"100336"}}