{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,2]],"date-time":"2026-10-02T01:29:23Z","timestamp":1790904563605,"version":"4.1.0"},"reference-count":36,"publisher":"Elsevier BV","issue":"3","license":[{"start":{"date-parts":[[2007,3,1]],"date-time":"2007-03-01T00:00:00Z","timestamp":1172707200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Journal of Clinical Virology"],"published-print":{"date-parts":[[2007,3]]},"DOI":"10.1016\/j.jcv.2006.12.005","type":"journal-article","created":{"date-parts":[[2007,1,23]],"date-time":"2007-01-23T12:58:18Z","timestamp":1169557098000},"page":"221-226","source":"Crossref","is-referenced-by-count":112,"title":["Epidemiological and clinical features of hMPV, RSV and RVs infections in young children"],"prefix":"10.1016","volume":"38","author":[{"given":"Catherine","family":"Manoha","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sophie","family":"Espinosa","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Serge-Ludwig","family":"Aho","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fr\u00e9d\u00e9ric","family":"Huet","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pierre","family":"Pothier","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.jcv.2006.12.005_bib1","doi-asserted-by":"crossref","first-page":"396","DOI":"10.1086\/499310","article-title":"Genetic variability of human metapneumovirus infection: evidence of a shift in viral genotype without a change in illness","volume":"193","author":"Agapov","year":"2006","journal-title":"J Infect Dis"},{"key":"10.1016\/j.jcv.2006.12.005_bib2","doi-asserted-by":"crossref","first-page":"634","DOI":"10.3201\/eid0906.030017","article-title":"Human metapneumovirus infections in hospitalized children","volume":"9","author":"Boivin","year":"2003","journal-title":"Emerg Infect Dis"},{"key":"10.1016\/j.jcv.2006.12.005_bib3","doi-asserted-by":"crossref","first-page":"1154","DOI":"10.3201\/eid1006.031097","article-title":"Global genetic diversity of human metapneumovirus fusion gene","volume":"10","author":"Boivin","year":"2004","journal-title":"Emerg Infect Dis"},{"key":"10.1016\/j.jcv.2006.12.005_bib4","doi-asserted-by":"crossref","first-page":"1626","DOI":"10.3201\/eid0912.030522","article-title":"Human metapneumovirus and respiratory syncytial virus","volume":"9","author":"Cuevas","year":"2003","journal-title":"Braz Emerg Infect Dis"},{"key":"10.1016\/j.jcv.2006.12.005_bib5","doi-asserted-by":"crossref","first-page":"281","DOI":"10.1002\/jmv.10391","article-title":"Seroprevalence of human metapneumovirus in Japan","volume":"70","author":"Ebihara","year":"2003","journal-title":"J Med Virol"},{"key":"10.1016\/j.jcv.2006.12.005_bib6","doi-asserted-by":"crossref","first-page":"1388","DOI":"10.1086\/382482","article-title":"A 1-year experience with human metapneumovirus in children aged 5 years","volume":"189","author":"Esper","year":"2004","journal-title":"J Infect Dis"},{"key":"10.1016\/j.jcv.2006.12.005_bib7","doi-asserted-by":"crossref","first-page":"785","DOI":"10.1086\/367901","article-title":"Human metapneumovirus infections in young and elderly adults","volume":"187","author":"Falsey","year":"2003","journal-title":"J Infect Dis"},{"key":"10.1016\/j.jcv.2006.12.005_bib8","doi-asserted-by":"crossref","first-page":"92","DOI":"10.1097\/00006454-200301000-00024","article-title":"Presence of the new human metapneumovirus in French children with bronchiolitis","volume":"22","author":"Freymouth","year":"2003","journal-title":"Pediatr Infect Dis J"},{"key":"10.1016\/j.jcv.2006.12.005_bib9","doi-asserted-by":"crossref","first-page":"2365","DOI":"10.1007\/s00705-005-0581-2","article-title":"Changing circulation rate of human metapneumovirus strains and types among hospitalized pediatric patients during three consecutive winter-spring seasons","volume":"150","author":"Gerna","year":"2005","journal-title":"Brief Report Arch Virol"},{"key":"10.1016\/j.jcv.2006.12.005_bib10","doi-asserted-by":"crossref","first-page":"486","DOI":"10.1002\/jmv.20116","article-title":"Human metapneumovirus infection in hospital referred South African children","volume":"73","author":"IJpma","year":"2004","journal-title":"J Med Virol"},{"key":"10.1016\/j.jcv.2006.12.005_bib11","doi-asserted-by":"crossref","first-page":"1095","DOI":"10.3201\/eid1006.030629","article-title":"Respiratory picornaviruses and respiratory syncytial virus as causative agents of acute expiratory wheezing in children","volume":"10","author":"Jartti","year":"2004","journal-title":"Emerg Infect Dis"},{"key":"10.1016\/j.jcv.2006.12.005_bib12","doi-asserted-by":"crossref","first-page":"1225","DOI":"10.1136\/bmj.310.6989.1225","article-title":"Community study of role of viral infections in exacerbations of asthma in 9\u201311 years old children","volume":"310","author":"Johnston","year":"1995","journal-title":"BMJ"},{"issue":"4 April","key":"10.1016\/j.jcv.2006.12.005_bib13","doi-asserted-by":"crossref","first-page":"394","DOI":"10.1016\/j.jcv.2005.12.009","article-title":"Seasonal distribution and phylogenetic analysis of human metapneumovirus among children in Osaka City","volume":"35","author":"Kaida","year":"2006","journal-title":"Jpn J Clin Virol"},{"key":"10.1016\/j.jcv.2006.12.005_bib14","doi-asserted-by":"crossref","first-page":"66","DOI":"10.1067\/mai.2003.33","article-title":"Rhinovirus-induced wheezing in infancy\u2014the first sign of childhood asthma?","volume":"111","author":"Kotaniemi-Syrjanen","year":"2003","journal-title":"J Allergy Clin Immunol"},{"key":"10.1016\/j.jcv.2006.12.005_bib15","doi-asserted-by":"crossref","first-page":"1244","DOI":"10.1093\/bioinformatics\/17.12.1244","article-title":"MEGA2: molecular evolutionary genetics analysis software","volume":"17","author":"Kumar","year":"2001","journal-title":"Bioinformatics"},{"key":"10.1016\/j.jcv.2006.12.005_bib16","doi-asserted-by":"crossref","first-page":"1074","DOI":"10.3201\/eid1107.050050","article-title":"Human metapneumovirus genetic variability","volume":"11","author":"Ludewick","year":"2005","journal-title":"S Afr Emerg Infect Dis"},{"key":"10.1016\/j.jcv.2006.12.005_bib17","doi-asserted-by":"crossref","first-page":"1913","DOI":"10.1086\/425013","article-title":"Use of the P gene to genotype human metapneumovirus identifies 4 viral subtypes","volume":"190","author":"Mackay","year":"2004","journal-title":"J Infect Dis"},{"key":"10.1016\/j.jcv.2006.12.005_bib18","doi-asserted-by":"crossref","first-page":"1705","DOI":"10.1086\/379771","article-title":"Human metapneumovirus-associated lower respiratory tract infections among hospitalized human immunodeficiency virus type 1 (HIV-1)-infected and HIV-1-uninfected African infants","volume":"37","author":"Madhi","year":"2003","journal-title":"Clin Infect Dis"},{"key":"10.1016\/j.jcv.2006.12.005_bib19","doi-asserted-by":"crossref","first-page":"981","DOI":"10.1128\/JCM.42.3.981-986.2004","article-title":"Real-time reverse transcriptase PCR assay for detection of human metapneumoviruses from all known genetic lineages","volume":"42","author":"Maertzdorf","year":"2004","journal-title":"J Clin Microbiol"},{"key":"10.1016\/j.jcv.2006.12.005_bib20","doi-asserted-by":"crossref","first-page":"700","DOI":"10.3201\/eid1004.030555","article-title":"Human metapneumovirus infection among children hospitalized with acute respiratory illness","volume":"10","author":"Mullins","year":"2004","journal-title":"Emerg Infect Dis"},{"key":"10.1016\/j.jcv.2006.12.005_bib21","doi-asserted-by":"crossref","first-page":"188","DOI":"10.5694\/j.1326-5377.2002.tb04354.x","article-title":"Evidence of human metapneumovirus in Australian children","volume":"176","author":"Nissen","year":"2002","journal-title":"Med J Aust"},{"key":"10.1016\/j.jcv.2006.12.005_bib22","doi-asserted-by":"crossref","first-page":"969","DOI":"10.1099\/jmm.0.46052-0","article-title":"Human metapneumovirus infections in Mexico: epidemiological and clinical characteristics","volume":"54","author":"Noyola","year":"2005","journal-title":"J Med Microbiol"},{"key":"10.1016\/j.jcv.2006.12.005_bib23","doi-asserted-by":"crossref","first-page":"179","DOI":"10.1016\/S0166-0934(99)00045-2","article-title":"Rhinovirus identification by BglI digestion of picornavirus RT-PCR amplicons","volume":"80","author":"Papadopoulos","year":"1999","journal-title":"J Virol Methods"},{"key":"10.1016\/j.jcv.2006.12.005_bib24","doi-asserted-by":"crossref","first-page":"628","DOI":"10.3201\/eid0906.030009","article-title":"Children with respiratory disease associated with metapneumovirus in Hong Kong","volume":"9","author":"Peiris","year":"2003","journal-title":"Emerg Infect Dis"},{"key":"10.1016\/j.jcv.2006.12.005_bib25","doi-asserted-by":"crossref","first-page":"976","DOI":"10.3201\/eid0809.020238","article-title":"Respiratory tract reinfections by the new human Metapneumovirus in an immunocompromised child","volume":"8","author":"Pelletier","year":"2002","journal-title":"Emerg Infect Dis"},{"key":"10.1016\/j.jcv.2006.12.005_bib26","doi-asserted-by":"crossref","first-page":"1660","DOI":"10.1086\/340518","article-title":"Characterization of human metapneumoviruses isolated from patients in North America","volume":"185","author":"Peret","year":"2002","journal-title":"J Infect Dis"},{"key":"10.1016\/j.jcv.2006.12.005_bib27","doi-asserted-by":"crossref","first-page":"98","DOI":"10.1002\/jmv.20329","article-title":"Seasonality and clinical features of human metapneumovirus infection in children in Northern Alberta","volume":"76","author":"Robinson","year":"2005","journal-title":"J Med Virol"},{"key":"10.1016\/j.jcv.2006.12.005_bib28","doi-asserted-by":"crossref","first-page":"59","DOI":"10.1016\/j.jcv.2005.05.010","article-title":"Detection and pathogenicity of human metapneumovirus respiratory infection in pediatric Italian patients during a winter\u2014spring season","volume":"35","author":"Sarasini","year":"2006","journal-title":"J Clin Virol"},{"key":"10.1016\/j.jcv.2006.12.005_bib29","doi-asserted-by":"crossref","first-page":"719","DOI":"10.1038\/89098","article-title":"A newly discovered human pneumovirus isolated from young children with respiratory tract disease","volume":"7","author":"van den Hoogen","year":"2001","journal-title":"Nat Med"},{"key":"10.1016\/j.jcv.2006.12.005_bib30","doi-asserted-by":"crossref","first-page":"1571","DOI":"10.1086\/379200","article-title":"Prevalence and clinical symptoms of human metapneumovirus infection in hospitalized patients","volume":"188","author":"van den Hoogen","year":"2003","journal-title":"J Infect Dis"},{"key":"10.1016\/j.jcv.2006.12.005_bib31","doi-asserted-by":"crossref","first-page":"658","DOI":"10.3201\/eid1004.030393","article-title":"Antigenic and genetic variability of human metapneumoviruses","volume":"10","author":"van den Hoogen","year":"2004","journal-title":"Emerg Infect Dis"},{"key":"10.1016\/j.jcv.2006.12.005_bib32","doi-asserted-by":"crossref","first-page":"3043","DOI":"10.1128\/JCM.41.7.3043-3045.2003","article-title":"High prevalence of human metapneumovirus infection in young children and genetic heterogeneity of the viral isolates","volume":"41","author":"Viazov","year":"2003","journal-title":"J Clin Microbiol"},{"key":"10.1016\/j.jcv.2006.12.005_bib33","doi-asserted-by":"crossref","first-page":"111","DOI":"10.1086\/504378","article-title":"Differences in clinical severity between genotype A and genotype B human metapneumovirus infection in children","volume":"42","author":"Vicente","year":"2006","journal-title":"Clin Infect Dis"},{"key":"10.1016\/j.jcv.2006.12.005_bib34","doi-asserted-by":"crossref","first-page":"443","DOI":"10.1056\/NEJMoa025472","article-title":"Human metapneumovirus and lower respiratory tract disease in otherwise healthy infants and children","volume":"350","author":"Williams","year":"2004","journal-title":"N Engl J Med"},{"key":"10.1016\/j.jcv.2006.12.005_bib35","doi-asserted-by":"crossref","first-page":"1311","DOI":"10.1016\/j.jaci.2005.02.001","article-title":"Human metapneumovirus infection in children hospitalized for wheezing","volume":"115","author":"Williams","year":"2005","journal-title":"J Allergy Clin Immunol"},{"key":"10.1016\/j.jcv.2006.12.005_bib36","doi-asserted-by":"crossref","first-page":"387","DOI":"10.1086\/499274","article-title":"The role of human metapneumovirus in upper respiratory tract infections in children: a 20-year experience","volume":"193","author":"Williams","year":"2006","journal-title":"J Infect Dis"}],"container-title":["Journal of Clinical Virology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1386653206004628?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1386653206004628?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2020,4,19]],"date-time":"2020-04-19T21:28:55Z","timestamp":1587331735000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1386653206004628"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2007,3]]},"references-count":36,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2007,3]]}},"alternative-id":["S1386653206004628"],"URL":"https:\/\/doi.org\/10.1016\/j.jcv.2006.12.005","relation":{},"ISSN":["1386-6532"],"issn-type":[{"value":"1386-6532","type":"print"}],"subject":[],"published":{"date-parts":[[2007,3]]}}}