{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,4]],"date-time":"2026-10-04T19:20:43Z","timestamp":1791141643077,"version":"4.1.0"},"reference-count":277,"publisher":"Elsevier BV","issue":"4","license":[{"start":{"date-parts":[[2008,8,1]],"date-time":"2008-08-01T00:00:00Z","timestamp":1217548800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Journal of Clinical Virology"],"published-print":{"date-parts":[[2008,8]]},"DOI":"10.1016\/j.jcv.2008.04.002","type":"journal-article","created":{"date-parts":[[2008,5,28]],"date-time":"2008-05-28T17:53:39Z","timestamp":1211997219000},"page":"297-320","source":"Crossref","is-referenced-by-count":92,"title":["Human rhinoviruses: The cold wars resume"],"prefix":"10.1016","volume":"42","author":[{"given":"Ian M.","family":"Mackay","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.jcv.2008.04.002_bib1","series-title":"Real-Time PCR in microbiology: from diagnosis to characterization","author":"PCR","year":"2007"},{"key":"10.1016\/j.jcv.2008.04.002_bib2","doi-asserted-by":"crossref","first-page":"605","DOI":"10.1097\/01.inf.0000168741.59747.2d","article-title":"Impact on clinical course of disease and interferon-g response","volume":"24","author":"Aberle","year":"2005","journal-title":"Pediatr Infect Dis J"},{"key":"10.1016\/j.jcv.2008.04.002_bib3","doi-asserted-by":"crossref","first-page":"340","DOI":"10.1128\/JVI.51.2.340-345.1984","article-title":"Many rhinovirus serotypes share the same cellular receptor","volume":"51","author":"Abraham","year":"1984","journal-title":"J Virol"},{"key":"10.1016\/j.jcv.2008.04.002_bib4","doi-asserted-by":"crossref","first-page":"1013","DOI":"10.1128\/JVI.00584-06","article-title":"Analysis of a new human parechovirus allows the definition of parechovirus types and the identification of RNA structural domains","volume":"81","author":"Al-Sunaidi","year":"2007","journal-title":"J Virol"},{"key":"10.1016\/j.jcv.2008.04.002_bib5","doi-asserted-by":"crossref","first-page":"524","DOI":"10.1128\/JCM.37.3.524-530.1999","article-title":"Improved detection of rhinoviruses in clinical samples by using a newly developed nested reverse transcription-PCR assay","volume":"37","author":"Andeweg","year":"1999","journal-title":"J Clin Microbiol"},{"issue":"3","key":"10.1016\/j.jcv.2008.04.002_bib6","doi-asserted-by":"crossref","first-page":"341","DOI":"10.1002\/1096-9071(200007)61:3<341::AID-JMV10>3.0.CO;2-0","article-title":"Differential detection of rhinoviruses and enteroviruses RNA sequences associated with classical immunofluorescence assay detection of respiratory virus antigens in nasopharyngeal swabs from infants with bronchiolitis","volume":"61","author":"Andr\u00e9oletti","year":"2000","journal-title":"J Med Virol"},{"key":"10.1016\/j.jcv.2008.04.002_bib7","doi-asserted-by":"crossref","first-page":"1274","DOI":"10.1126\/science.146.3649.1274","article-title":"The complex epidemiology of respiratory virus infections","volume":"146","author":"Andrewes","year":"1964","journal-title":"Science"},{"key":"10.1016\/j.jcv.2008.04.002_bib8","doi-asserted-by":"crossref","first-page":"361","DOI":"10.1146\/annurev.me.17.020166.002045","article-title":"Rhinoviruses and common colds","volume":"17","author":"Andrewes","year":"1966","journal-title":"Ann Rev Med"},{"key":"10.1016\/j.jcv.2008.04.002_bib9","doi-asserted-by":"crossref","first-page":"546","DOI":"10.1016\/S0140-6736(53)90279-7","article-title":"Propagation of common-cold virus in tissue cultures","volume":"265","author":"Andrewes","year":"1953","journal-title":"Lancet"},{"key":"10.1016\/j.jcv.2008.04.002_bib10","doi-asserted-by":"crossref","first-page":"1117","DOI":"10.1128\/JVI.64.3.1117-1123.1990","article-title":"Two groups of rhinoviruses revealed by a panel of antiviral compounds present sequence divergence and differential pathogenicity","volume":"64","author":"Andries","year":"1990","journal-title":"J Virol"},{"key":"10.1016\/j.jcv.2008.04.002_bib11","doi-asserted-by":"crossref","first-page":"1232","DOI":"10.1002\/jmv.20689","article-title":"Frequent detection of human rhinoviruses, paramyxoviruses, coronaviruses, and bocavirus during acute respiratory tract infections","volume":"78","author":"Arden","year":"2006","journal-title":"J Med Virol"},{"key":"10.1016\/j.jcv.2008.04.002_bib12","doi-asserted-by":"crossref","first-page":"e631","DOI":"10.1542\/peds.2006-3073","article-title":"Undiagnosed respiratory viruses in children","volume":"121","author":"Arnold","year":"2008","journal-title":"Pediatrics"},{"key":"10.1016\/j.jcv.2008.04.002_bib13","doi-asserted-by":"crossref","first-page":"373","DOI":"10.1006\/mcpr.1993.1055","article-title":"Detection of human rhinovirus RNA in nasal washings by PCR","volume":"7","author":"Arruda","year":"1993","journal-title":"Mol Cell Probes"},{"key":"10.1016\/j.jcv.2008.04.002_bib14","doi-asserted-by":"crossref","first-page":"2864","DOI":"10.1128\/JCM.35.11.2864-2868.1997","article-title":"Frequency and natural history of rhinovirus infections in adults during autumn","volume":"35","author":"Arruda","year":"1997","journal-title":"J Clin Microbiol"},{"key":"10.1016\/j.jcv.2008.04.002_bib15","doi-asserted-by":"crossref","first-page":"266","DOI":"10.1086\/430927","article-title":"Uncommon(ly considered) manifestations of infection with rhinovirus, agent of the common cold","volume":"41","author":"Atmar","year":"2005","journal-title":"Clin Infect Dis"},{"key":"10.1016\/j.jcv.2008.04.002_bib16","doi-asserted-by":"crossref","first-page":"63","DOI":"10.1007\/s00431-007-0427-x","article-title":"Clinical findings and unusual epidemiologic characteristics of human metapneumovirus infections in children in the region of Basel, Switzerland","volume":"167","author":"Baer","year":"2007","journal-title":"Eur J. Pediatr"},{"key":"10.1016\/j.jcv.2008.04.002_bib17","doi-asserted-by":"crossref","first-page":"319","DOI":"10.1136\/bmj.2.5457.319","article-title":"A collaborative study of the aetiology of acute respiratory infections in Britain 1961-4. A report of the medical research council working party on acute respiratory virus infections","volume":"2","author":"Banham","year":"1965","journal-title":"Br Med J"},{"key":"10.1016\/j.jcv.2008.04.002_bib18","doi-asserted-by":"crossref","first-page":"809","DOI":"10.1111\/j.1365-2222.1992.tb02825.x","article-title":"Viruses as precipitants of asthma symptoms II. Physiology and mechanisms","volume":"22","author":"Bardin","year":"1992","journal-title":"Clin Exp Allergy"},{"key":"10.1016\/j.jcv.2008.04.002_bib19","doi-asserted-by":"crossref","first-page":"358","DOI":"10.1183\/09031936.06.00002606","article-title":"Relations among questionnaire and laboratory measures of rhinovirus infection","volume":"28","author":"Barrett","year":"2006","journal-title":"Eur Respir J"},{"key":"10.1016\/j.jcv.2008.04.002_bib20","doi-asserted-by":"crossref","first-page":"199","DOI":"10.1038\/nm1713","article-title":"Mouse models of rhinovirus-induced disease and exacerbation of allergic airway inflammation","volume":"14","author":"Bartlett","year":"2008","journal-title":"Nat Med"},{"key":"10.1016\/j.jcv.2008.04.002_bib21","doi-asserted-by":"crossref","first-page":"1608","DOI":"10.1128\/JB.88.6.1608-1611.1964","article-title":"Growth, plaque production and cationic stabilization of rhinovirus type 1 (Echovirus 28)","volume":"88","author":"Behbehani","year":"1964","journal-title":"J Bacteriol"},{"key":"10.1016\/j.jcv.2008.04.002_bib22","doi-asserted-by":"crossref","first-page":"42S","DOI":"10.1016\/S0002-9343(01)01063-4","article-title":"Cost burden of viral respiratory infections: Issues for formulary decision makers","volume":"112","author":"Bertino","year":"2002","journal-title":"Am J Med"},{"key":"10.1016\/j.jcv.2008.04.002_bib23","doi-asserted-by":"crossref","first-page":"223","DOI":"10.1016\/S0166-0934(03)00038-7","article-title":"Detection of rhinovirus and enterovirus in upper respiratory tract samples using a multiplex nested PCR","volume":"108","author":"Billaud","year":"2003","journal-title":"J Virol Methods"},{"key":"10.1016\/j.jcv.2008.04.002_bib24","doi-asserted-by":"crossref","first-page":"4366","DOI":"10.1128\/AAC.00905-07","article-title":"In vitro resistance studies of Rupintrivir, a novel inhibitor of human rhinovirus 3C protease","volume":"51","author":"Binford","year":"2007","journal-title":"Antimicrob Agents Chemother"},{"key":"10.1016\/j.jcv.2008.04.002_bib25","doi-asserted-by":"crossref","first-page":"263","DOI":"10.1002\/jmv.2140","article-title":"Virological and serological analysis of rhinovirus infections during the first two years of life in a cohort of children","volume":"66","author":"Blomqvist","year":"2002","journal-title":"J Med Virol"},{"key":"10.1016\/j.jcv.2008.04.002_bib26","doi-asserted-by":"crossref","first-page":"2813","DOI":"10.1128\/JCM.37.9.2813-2816.1999","article-title":"Rapid detection of human rhinoviruses in nasopharyngeal aspirates by a microwell reverse transcription-PCR-hybridization assay","volume":"37","author":"Blomqvist","year":"1999","journal-title":"J Clin Microbiol"},{"key":"10.1016\/j.jcv.2008.04.002_bib27","doi-asserted-by":"crossref","first-page":"38","DOI":"10.1001\/jama.1963.63710010001012","article-title":"Relationship of rhinovirus infection to mild upper respiratory disease","volume":"186","author":"Bloom","year":"1963","journal-title":"J Am Med Assoc"},{"key":"10.1016\/j.jcv.2008.04.002_bib28","doi-asserted-by":"crossref","first-page":"310","DOI":"10.3201\/eid1102.040492","article-title":"Diagnostic system for rapid and sensitive differential detection of pathogens","volume":"11","author":"Briese","year":"2005","journal-title":"Emerg Infect Dis"},{"key":"10.1016\/j.jcv.2008.04.002_bib29","doi-asserted-by":"crossref","first-page":"97","DOI":"10.1128\/JCM.01117-07","article-title":"Evidence from multiplex molecular assays for complex multipathogen interactions in acute respiratory infections","volume":"46","author":"Brunstein","year":"2008","journal-title":"J Clin Microbiol"},{"key":"10.1016\/j.jcv.2008.04.002_bib30","doi-asserted-by":"crossref","first-page":"1147","DOI":"10.1016\/S0140-6736(05)71877-8","article-title":"WHO estimates of the causes of death inchildren","volume":"365","author":"Bryce","year":"2005","journal-title":"Lancet"},{"key":"10.1016\/j.jcv.2008.04.002_bib31","doi-asserted-by":"crossref","first-page":"169","DOI":"10.4049\/jimmunol.108.1.169","article-title":"Further characterization of the local respiratory tract antibody response induced by intranasal instillation of inactivated rhinovirus 13 vaccine","volume":"108","author":"Buscho","year":"1972","journal-title":"J Immunol"},{"key":"10.1016\/j.jcv.2008.04.002_bib32","doi-asserted-by":"crossref","first-page":"95","DOI":"10.1093\/oxfordjournals.aje.a120501","article-title":"Production of tracheobronchitis in volunteers with rhinovirus in a small-particle aerosol","volume":"81","author":"Cate","year":"1965","journal-title":"Am J Epidemiol"},{"key":"10.1016\/j.jcv.2008.04.002_bib33","doi-asserted-by":"crossref","first-page":"56","DOI":"10.1172\/JCI104894","article-title":"Studies with rhinoviruses in volunteers: production of illness, effect of naturally acquired antibody, and demonstration of a protective effect not associated with serum antibody","volume":"43","author":"Cate","year":"1964","journal-title":"J Clin Invest"},{"key":"10.1016\/j.jcv.2008.04.002_bib34","doi-asserted-by":"crossref","first-page":"352","DOI":"10.1093\/oxfordjournals.aje.a120648","article-title":"The role of nasal secretion and serum antibody in the rhinovirus common cold","volume":"84","author":"Cate","year":"1966","journal-title":"Am J Epidemiol"},{"key":"10.1016\/j.jcv.2008.04.002_bib35","doi-asserted-by":"crossref","first-page":"484","DOI":"10.1002\/jmv.20008","article-title":"Simultaneous detection of fourteen respiratory viruses in clinical specimens by two multiplex reverse transcription nested-PCR assays","volume":"72","author":"Coiras","year":"2004","journal-title":"J Med Virol"},{"key":"10.1016\/j.jcv.2008.04.002_bib36","doi-asserted-by":"crossref","first-page":"1115","DOI":"10.1136\/thx.51.11.1115","article-title":"Effects of upper respiratory tract infections in patients with cystic fibrosis","volume":"51","author":"Collinson","year":"1996","journal-title":"Thorax"},{"key":"10.1016\/j.jcv.2008.04.002_bib37","doi-asserted-by":"crossref","first-page":"7","DOI":"10.1128\/JVI.57.1.7-12.1986","article-title":"Isolation of a monoclonal antibody that blocks attachment of the major group of human rhinoviruses","volume":"57","author":"Colonno","year":"1986","journal-title":"J Virol"},{"key":"10.1016\/j.jcv.2008.04.002_bib38","doi-asserted-by":"crossref","first-page":"1264","DOI":"10.1038\/2171264a0","article-title":"Identification of rhinovirus strain D.C.","volume":"217","author":"Conant","year":"1968","journal-title":"Nature"},{"key":"10.1016\/j.jcv.2008.04.002_bib39","doi-asserted-by":"crossref","first-page":"107","DOI":"10.4049\/jimmunol.100.1.107","article-title":"Rhinoviruses: Basis for a numbering system. II Serologic characterization of prototype strains","volume":"100","author":"Conant","year":"1968","journal-title":"J Immunol"},{"key":"10.1016\/j.jcv.2008.04.002_bib40","doi-asserted-by":"crossref","first-page":"1023","DOI":"10.1038\/nm1462","article-title":"Role of deficient type III interferon-l production in asthma exacerbations","volume":"12","author":"Contoli","year":"2006","journal-title":"Nat Med"},{"key":"10.1016\/j.jcv.2008.04.002_bib41","doi-asserted-by":"crossref","first-page":"286","DOI":"10.1093\/oxfordjournals.aje.a121459","article-title":"The seattle virus Watch. III. Evaluation of isolation methods and summary of infections detected by virus isolations","volume":"96","author":"Cooney","year":"1972","journal-title":"Am J Epidemiol"},{"key":"10.1016\/j.jcv.2008.04.002_bib42","doi-asserted-by":"crossref","first-page":"202","DOI":"10.1128\/jcm.5.2.202-207.1977","article-title":"Demonstration of dual rhinovirus infection in humans by isolation of different serotypes in human heteroploid (HeLa) and human diploid fibroblast cell cultures","volume":"5","author":"Cooney","year":"1977","journal-title":"J Clin Microbiol"},{"key":"10.1016\/j.jcv.2008.04.002_bib43","doi-asserted-by":"crossref","first-page":"167","DOI":"10.1093\/infdis\/150.2.167","article-title":"The common cold: control?","volume":"150","author":"Couch","year":"1984","journal-title":"J Infect Dis"},{"key":"10.1016\/j.jcv.2008.04.002_bib44","doi-asserted-by":"crossref","first-page":"78","DOI":"10.1093\/oxfordjournals.aje.a121115","article-title":"Airborne transmission of respiratory infection with Coxsackievirus A type 21","volume":"91","author":"Couch","year":"1970","journal-title":"Am J Epidemiol"},{"key":"10.1016\/j.jcv.2008.04.002_bib45","doi-asserted-by":"crossref","first-page":"1403","DOI":"10.1056\/NEJM196912182812506","article-title":"Pulmonary infection due to rhinovirus type 13","volume":"281","author":"Craighead","year":"1969","journal-title":"N Engl J Med"},{"key":"10.1016\/j.jcv.2008.04.002_bib46","doi-asserted-by":"crossref","first-page":"189","DOI":"10.1093\/infdis\/150.2.189","article-title":"Short-duration exposure and the transmission of rhinoviral colds","volume":"150","author":"D\u2019Alessio","year":"1984","journal-title":"J Infect Dis"},{"key":"10.1016\/j.jcv.2008.04.002_bib47","doi-asserted-by":"crossref","first-page":"3212","DOI":"10.1128\/JCM.42.7.3212-3218.2004","article-title":"Amplicon sequencing and improved detection of human rhinovirus in respiratory samples","volume":"42","author":"Deffernez","year":"2004","journal-title":"J Clin Microbiol"},{"key":"10.1016\/j.jcv.2008.04.002_bib48","doi-asserted-by":"crossref","first-page":"386","DOI":"10.1093\/oxfordjournals.aje.a120749","article-title":"Epidemiology of infections with rhinovirus types 43 and 55 in a group of university of Wisconsin student families","volume":"86","author":"Dick","year":"1967","journal-title":"Am J Epidemiol"},{"key":"10.1016\/j.jcv.2008.04.002_bib49","doi-asserted-by":"crossref","first-page":"234","DOI":"10.3181\/00379727-123-31454","article-title":"Growth and cytopathic effect of H type rhinoviruses in monkey kidney tissue culture","volume":"123","author":"Douglas","year":"1966","journal-title":"Proc Soc Exp Biol Med"},{"key":"10.1016\/j.jcv.2008.04.002_bib50","first-page":"159","article-title":"Quantitative rhinovirus shedding patterns in volunteers","volume":"94","author":"Douglas","year":"1966","journal-title":"Am Rev Resp Dis"},{"key":"10.1016\/j.jcv.2008.04.002_bib51","doi-asserted-by":"crossref","first-page":"181","DOI":"10.1007\/s00018-006-6266-5","article-title":"The cold case: are rhinoviruses perfectly adapted pathogens?","volume":"64","author":"Dreschers","year":"2007","journal-title":"Cell and Mol Life Sci"},{"key":"10.1016\/j.jcv.2008.04.002_bib52","doi-asserted-by":"crossref","first-page":"578","DOI":"10.12968\/hmed.2007.68.2.22824","article-title":"Mechanisms of symptoms of the common cold and influenza","volume":"68","author":"Eccles","year":"2007","journal-title":"Br J Hosp Med"},{"key":"10.1016\/j.jcv.2008.04.002_bib53","doi-asserted-by":"crossref","first-page":"96","DOI":"10.1086\/313937","article-title":"Spectrum of clinical illness in hospitalized patients with \u201cCommon cold\u201d virus infections","volume":"31","author":"El-Sahly","year":"2000","journal-title":"Clin Infect Dis"},{"key":"10.1016\/j.jcv.2008.04.002_bib54","doi-asserted-by":"crossref","first-page":"735","DOI":"10.1056\/NEJM197510092931502","article-title":"Siniusitis of the maxillary antrum","volume":"293","author":"Evans","year":"1975","journal-title":"N Engl J Med"},{"key":"10.1016\/j.jcv.2008.04.002_bib55","doi-asserted-by":"crossref","first-page":"1715","DOI":"10.1128\/JB.92.6.1710-1715.1966","article-title":"Enhancement of rhinovirus plaque formation in human heteroploid cell cultures by magnesium and calcium","volume":"92","author":"Fiala","year":"1966","journal-title":"J Bacteriol"},{"key":"10.1016\/j.jcv.2008.04.002_bib56","doi-asserted-by":"crossref","first-page":"122","DOI":"10.1093\/oxfordjournals.aje.a112078","article-title":"The Seattle virus watch. V. Epidemiologic observation of hrinovirus infections, 1965\u20131969 in families with young children","volume":"101","author":"Fox","year":"1975","journal-title":"Am J Epidemiol"},{"key":"10.1016\/j.jcv.2008.04.002_bib57","doi-asserted-by":"crossref","first-page":"31","DOI":"10.1016\/S0928-0197(97)00060-3","article-title":"Detection of respiratory syncytial virus, parainfluenzavirus 3, adenovirus and rhinovirus sequences in respiratory tract of infants by polymerase chain reaction and hybridization","volume":"8","author":"Freymuth","year":"2000","journal-title":"Clin Diagn Virol"},{"key":"10.1016\/j.jcv.2008.04.002_bib58","doi-asserted-by":"crossref","first-page":"115","DOI":"10.1097\/00006454-199302000-00002","article-title":"Potential interventions for preventing pneumonia among young children: lack of effect of antibiotic treatment for upper respiratory infections","volume":"12","author":"Gadomski","year":"1993","journal-title":"Pediatr Infect Dis J"},{"key":"10.1016\/j.jcv.2008.04.002_bib59","doi-asserted-by":"crossref","first-page":"9346","DOI":"10.1093\/nar\/16.19.9346","article-title":"Polymerase chain reaction amplification of rhinovirus nucleic acids from clinical material","volume":"16","author":"Gama","year":"1988","journal-title":"Nucleic Acids Res"},{"key":"10.1016\/j.jcv.2008.04.002_bib60","doi-asserted-by":"crossref","first-page":"132","DOI":"10.1038\/nri725","article-title":"Relationship of viral infections to wheezing illnesses and asthma","volume":"2","author":"Gern","year":"2002","journal-title":"Nat Rev Immunol"},{"key":"10.1016\/j.jcv.2008.04.002_bib61","doi-asserted-by":"crossref","first-page":"1159","DOI":"10.1164\/ajrccm.155.3.9117003","article-title":"Detection of rhinovirus RNA in lower airway cells during experimentally induced infection","volume":"155","author":"Gern","year":"2008","journal-title":"Am J Respir Crit Care Med"},{"key":"10.1016\/j.jcv.2008.04.002_bib62","doi-asserted-by":"crossref","first-page":"2226","DOI":"10.1164\/ajrccm.162.6.2003019","article-title":"Relationship of upper and lower airway cytokines to outcome of experimental rhinovirus infection","volume":"162","author":"Gern","year":"2000","journal-title":"Am J Respir Crit Care Med"},{"key":"10.1016\/j.jcv.2008.04.002_bib63","doi-asserted-by":"crossref","first-page":"498","DOI":"10.1056\/NEJM197303082881005","article-title":"Epidemiology of acute lower respiratory disease in children","volume":"288","author":"Glezen","year":"1973","journal-title":"N Engl J Med"},{"key":"10.1016\/j.jcv.2008.04.002_bib64","doi-asserted-by":"crossref","first-page":"397","DOI":"10.1016\/S0022-3476(71)80218-4","article-title":"Epidemiologic patterns of acute lower respiratory disease of children in a pediatric group practice","volume":"78","author":"Glezen","year":"1971","journal-title":"J Pediatr"},{"key":"10.1016\/j.jcv.2008.04.002_bib65","doi-asserted-by":"crossref","first-page":"1277","DOI":"10.1093\/infdis\/162.6.1277","article-title":"Adverse effects of aspirin, acetaminophen, and ibuprofen on immune function, viral shedding, and clinical status in rhinovirus-infected volunteers","volume":"162","author":"Graham","year":"1990","journal-title":"J Infect Dis"},{"key":"10.1016\/j.jcv.2008.04.002_bib66","first-page":"1","article-title":"Synergism between allergens and viruses and risk of hospital admission with asthma: case-control study","volume":"324","author":"Green","year":"2007","journal-title":"Br Med J"},{"key":"10.1016\/j.jcv.2008.04.002_bib67","doi-asserted-by":"crossref","first-page":"839","DOI":"10.1016\/0092-8674(89)90688-0","article-title":"The major human rhinovirus receptor is ICAM-1","volume":"56","author":"Greve","year":"1989","journal-title":"Cell"},{"key":"10.1016\/j.jcv.2008.04.002_bib68","doi-asserted-by":"crossref","first-page":"1137","DOI":"10.3181\/00379727-122-31345","article-title":"Micro-neutralization test for identification of rhinovirus serotypes","volume":"122","author":"Gwaltney","year":"1966","journal-title":"Proc Soc Exp Biol Med"},{"key":"10.1016\/j.jcv.2008.04.002_bib69","doi-asserted-by":"crossref","first-page":"33S","DOI":"10.1016\/S0002-9343(01)01062-2","article-title":"Viral respiratory infection therapy: historical perspectives and current trials","volume":"112","author":"Gwaltney","year":"2002","journal-title":"Am J Med"},{"key":"10.1016\/j.jcv.2008.04.002_bib70","doi-asserted-by":"crossref","first-page":"287","DOI":"10.1016\/0166-3542(95)00935-3","article-title":"The influence of signal variation, bias, noise and effect size on statistical significance in treatment studies of the common cold","volume":"29","author":"Gwaltney","year":"1996","journal-title":"Antiviral Res"},{"key":"10.1016\/j.jcv.2008.04.002_bib71","doi-asserted-by":"crossref","first-page":"357","DOI":"10.1093\/oxfordjournals.aje.a112555","article-title":"Rhinovirus transmission one if by air, two if by hand","volume":"107","author":"Gwaltney","year":"1978","journal-title":"Am J Epidemiol"},{"key":"10.1016\/j.jcv.2008.04.002_bib72","doi-asserted-by":"crossref","first-page":"1261","DOI":"10.1056\/NEJM196612082752301","article-title":"Rhinovirus infections in an industrial population I. The occurrence of illness","volume":"275","author":"Gwaltney","year":"1966","journal-title":"N Engl J Med"},{"key":"10.1016\/j.jcv.2008.04.002_bib73","doi-asserted-by":"crossref","first-page":"409","DOI":"10.1128\/MMBR.28.4.409-422.1964","article-title":"Rhinoviruses and respiratory disease","volume":"28","author":"Gwaltney","year":"1964","journal-title":"Bacteriol Rev"},{"key":"10.1016\/j.jcv.2008.04.002_bib74","doi-asserted-by":"crossref","first-page":"147","DOI":"10.1086\/341455","article-title":"Combined antiviral-antimediator treatment for the common cold","volume":"186","author":"Gwaltney","year":"2002","journal-title":"J Infect Dis"},{"key":"10.1016\/j.jcv.2008.04.002_bib75","doi-asserted-by":"crossref","first-page":"463","DOI":"10.7326\/0003-4819-88-4-463","article-title":"Hand-to-hand transmission of rhinovirus colds","volume":"88","author":"Gwaltney","year":"1978","journal-title":"Ann. Intern Med"},{"key":"10.1016\/j.jcv.2008.04.002_bib76","doi-asserted-by":"crossref","first-page":"1732","DOI":"10.1172\/JCI4141","article-title":"Mechanism of rhinovirus-induced changes in airway smooth muscle responsiveness","volume":"102","author":"Hakonarson","year":"1998","journal-title":"J Clin Invest"},{"key":"10.1016\/j.jcv.2008.04.002_bib77","first-page":"98","article-title":"Bioedit: a user-friendly biological sequence alignment editor and analysis program for Windows 95\/98\/NT","volume":"41","author":"Hall","year":"1999","journal-title":"Nucleic Acids Symp Ser"},{"key":"10.1016\/j.jcv.2008.04.002_bib78","doi-asserted-by":"crossref","first-page":"648","DOI":"10.1128\/JCM.33.3.648-653.1995","article-title":"Detection of enteroviruses and rhinoviruses in clinical specimens by PCR and liquid-phase hybridization","volume":"33","author":"Halonen","year":"1995","journal-title":"J Clin Microbiol"},{"key":"10.1016\/j.jcv.2008.04.002_bib79","doi-asserted-by":"crossref","first-page":"191","DOI":"10.1016\/0042-6822(87)90367-9","article-title":"A collaborative report: Rhinoviruses \u2013 extension of the numbering system from 89 to 100","volume":"159","author":"Hamparian","year":"1987","journal-title":"Virology"},{"key":"10.1016\/j.jcv.2008.04.002_bib80","doi-asserted-by":"crossref","first-page":"444","DOI":"10.3181\/00379727-108-26962","article-title":"Recovery of new viruses (Coryzavirus) from cases of common cold in human adults","volume":"108","author":"Hamparian","year":"1961","journal-title":"Proc Soc Exp Biol Med"},{"key":"10.1016\/j.jcv.2008.04.002_bib81","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1159\/000386458","article-title":"Rhinoviruses","volume":"1","author":"Hamre","year":"1967","journal-title":"Monogr Virol"},{"key":"10.1016\/j.jcv.2008.04.002_bib82","doi-asserted-by":"crossref","first-page":"238","DOI":"10.1093\/oxfordjournals.aje.a120579","article-title":"Virologic studies of acute respiratory disease in young adults. IV. Virus isolations during four years of surveillance","volume":"83","author":"Hamre","year":"1966","journal-title":"Am J Epidemiol"},{"key":"10.1016\/j.jcv.2008.04.002_bib83","doi-asserted-by":"crossref","first-page":"727","DOI":"10.1128\/AAC.36.4.727","article-title":"Safety and efficacy of intrabnasal Pirodavir (R77975) in experimental rhinovirus infection","volume":"36","author":"Hayden","year":"1992","journal-title":"Antimicrob Agents Chemother"},{"key":"10.1016\/j.jcv.2008.04.002_bib84","doi-asserted-by":"crossref","first-page":"174","DOI":"10.1093\/infdis\/150.2.174","article-title":"Intranasal interferon-a treatment of experimental rhinoviral colds","volume":"150","author":"Hayden","year":"1984","journal-title":"J Infect Dis"},{"key":"10.1016\/j.jcv.2008.04.002_bib85","doi-asserted-by":"crossref","first-page":"1523","DOI":"10.1086\/375069","article-title":"Efficacy and safety of oral pleconaril for treatment of colds due to picornaviruses in adults: results of 2 double-blind, randomized, placebo-controlled trials","volume":"36","author":"Hayden","year":"2003","journal-title":"Clin Infect Dis"},{"key":"10.1016\/j.jcv.2008.04.002_bib86","doi-asserted-by":"crossref","first-page":"914","DOI":"10.1093\/infdis\/148.5.914","article-title":"Human tolerance and histopathologic effects of long-term administration of intranasal interferon-a2","volume":"148","author":"Hayden","year":"1983","journal-title":"J Infect Dis"},{"key":"10.1016\/j.jcv.2008.04.002_bib87","doi-asserted-by":"crossref","first-page":"230","DOI":"10.1128\/CMR.16.2.230-241.2003","article-title":"Importance of respiratory viruses in acute otitis media","volume":"16","author":"Heikkinen","year":"2003","journal-title":"Clin Microbiol Rev"},{"key":"10.1016\/j.jcv.2008.04.002_bib88","doi-asserted-by":"crossref","first-page":"183","DOI":"10.1016\/S0022-3476(79)80647-2","article-title":"The etiologic and epidemiologic spectrum of bronchiolitis in pediatric practice","volume":"95","author":"Henderson","year":"1979","journal-title":"J Pediatr"},{"key":"10.1016\/j.jcv.2008.04.002_bib89","doi-asserted-by":"crossref","first-page":"847","DOI":"10.1086\/513921","article-title":"The host response, not the virus, causes the symptoms of the common cold","volume":"26","author":"Hendley","year":"1998","journal-title":"Clin Infect Dis"},{"key":"10.1016\/j.jcv.2008.04.002_bib90","doi-asserted-by":"crossref","first-page":"243","DOI":"10.1093\/infdis\/125.3.243","article-title":"Relation between naturally acquired immunity and infectivity of two rhinoviruses in volunteers","volume":"125","author":"Hendley","year":"1972","journal-title":"J Infect Dis"},{"key":"10.1016\/j.jcv.2008.04.002_bib91","doi-asserted-by":"crossref","first-page":"242","DOI":"10.1093\/oxfordjournals.epirev.a036024","article-title":"Mechanisms of transmission of rhinovirus infections","volume":"10","author":"Hendley","year":"1988","journal-title":"Epidemiol Rev"},{"key":"10.1016\/j.jcv.2008.04.002_bib92","doi-asserted-by":"crossref","first-page":"184","DOI":"10.1093\/oxfordjournals.aje.a120928","article-title":"Rhinovirus infections in an industrial population. IV. Infections within families of employees during two fall peaks of respiratory illness","volume":"89","author":"Hendley","year":"1969","journal-title":"Am J Epidemiol"},{"key":"10.1016\/j.jcv.2008.04.002_bib93","doi-asserted-by":"crossref","first-page":"1361","DOI":"10.1056\/NEJM197306282882601","article-title":"Transmission of rhinovirus colds by self-inoculation","volume":"288","author":"Hendley","year":"1973","journal-title":"N Engl J Med"},{"key":"10.1016\/j.jcv.2008.04.002_bib94","doi-asserted-by":"crossref","first-page":"1284","DOI":"10.1164\/rccm.200609-1387ED","article-title":"Rhinovirus infections More than a common cold","volume":"174","author":"Hershenson","year":"2006","journal-title":"Am J Respir Crit Care Med"},{"key":"10.1016\/j.jcv.2008.04.002_bib95","doi-asserted-by":"crossref","first-page":"S217","DOI":"10.1097\/01.inf.0000188164.33856.f9","article-title":"Role of viral infections, atopy and antiviral immunity in the etiology of wheezing exacerbations among children and young adults","volume":"24","author":"Heymann","year":"2005","journal-title":"Pediatr Infect Dis J"},{"key":"10.1016\/j.jcv.2008.04.002_bib96","doi-asserted-by":"crossref","first-page":"1839","DOI":"10.1073\/pnas.91.5.1839","article-title":"Members of the low density lipoprotein receptor family mediate cell entry of a minor group common cold virus","volume":"91","author":"Hofer","year":"1994","journal-title":"Proc Natl Acad Sci USA"},{"key":"10.1016\/j.jcv.2008.04.002_bib97","doi-asserted-by":"crossref","first-page":"379","DOI":"10.1017\/S0022172400055303","article-title":"Studies of experimental rhinovirus type 2 infections in polar isolation and in England","volume":"76","author":"Holmes","year":"1976","journal-title":"J Hyg"},{"key":"10.1016\/j.jcv.2008.04.002_bib98","doi-asserted-by":"crossref","first-page":"2943","DOI":"10.1099\/0022-1317-70-11-2943","article-title":"The complete nucleotide sequence of Coxsackievirus A21","volume":"70","author":"Hughes","year":"1989","journal-title":"J Gen Virol"},{"key":"10.1016\/j.jcv.2008.04.002_bib99","doi-asserted-by":"crossref","first-page":"81","DOI":"10.1034\/j.1600-0463.2000.d01-31.x","article-title":"How sequence information helps us understand the evolution and dissemination of viruses","volume":"108","author":"Hungnes","year":"2000","journal-title":"Acta Pathol Immunol Microbiol Scand"},{"key":"10.1016\/j.jcv.2008.04.002_bib100","doi-asserted-by":"crossref","first-page":"2472","DOI":"10.1016\/j.rmed.2007.07.015","article-title":"A community-based, time-matched, case-control study of respiratory viruses and exacerbations of COPD","volume":"101","author":"Hutchinson","year":"2007","journal-title":"Respir Med"},{"key":"10.1016\/j.jcv.2008.04.002_bib101","doi-asserted-by":"crossref","first-page":"3261","DOI":"10.1099\/0022-1317-70-12-3261","article-title":"Polymerase chain reaction for human picornaviruses","volume":"70","author":"Hyypi\u00e4","year":"1989","journal-title":"J Gen Virol"},{"key":"10.1016\/j.jcv.2008.04.002_bib102","doi-asserted-by":"crossref","first-page":"96","DOI":"10.1002\/jmv.1890400204","article-title":"Improved detection of rhinoviruses in nasal and throat swabs by seminested RT-PCR","volume":"40","author":"Ireland","year":"1993","journal-title":"J Med Virol"},{"key":"10.1016\/j.jcv.2008.04.002_bib103","doi-asserted-by":"crossref","first-page":"136","DOI":"10.1159\/000065866","article-title":"Human rhinovirus 87 identified as human enterovirus 68 by VP4-based molecular diagnosis","volume":"45","author":"Ishiko","year":"2002","journal-title":"Intervirology"},{"key":"10.1016\/j.jcv.2008.04.002_bib104","doi-asserted-by":"crossref","first-page":"762","DOI":"10.1172\/JCI103857","article-title":"Transmission of the common cold to volunteers under controlled conditions. IV. Specific immunity to the common cold","volume":"38","author":"Jackson","year":"1959","journal-title":"J Clin Invest"},{"key":"10.1016\/j.jcv.2008.04.002_bib105","doi-asserted-by":"crossref","first-page":"463","DOI":"10.1016\/j.jcv.2005.11.009","article-title":"Association of respiratory picornaviruses with acute bronchiolitis in French infants","volume":"35","author":"Jacques","year":"2006","journal-title":"J Clin Virol"},{"issue":"5","key":"10.1016\/j.jcv.2008.04.002_bib106","doi-asserted-by":"crossref","first-page":"517","DOI":"10.1165\/rcmb.2007-0050OC","article-title":"Basal cells of differentiated bronchial epithelium are more susceptible to rhinovirus infection","volume":"38","author":"Jakiela","year":"2008","journal-title":"Am J Respir Cell Mol Biol"},{"key":"10.1016\/j.jcv.2008.04.002_bib107","doi-asserted-by":"crossref","first-page":"695","DOI":"10.1002\/jmv.20027","article-title":"Persistence of rhinovirus and enterovirus RNA after acute respiratory illness in children","volume":"72","author":"Jartti","year":"2004","journal-title":"J Med Virol"},{"key":"10.1016\/j.jcv.2008.04.002_bib108","doi-asserted-by":"crossref","first-page":"1095","DOI":"10.3201\/eid1006.030629","article-title":"Respiratory picornaviruses and respiratory syncytial virus as causative agents of acute expiratory wheezing in children","volume":"10","author":"Jartti","year":"2004","journal-title":"Emerg Infect Dis"},{"key":"10.1016\/j.jcv.2008.04.002_bib109","doi-asserted-by":"crossref","first-page":"46","DOI":"10.1378\/chest.45.1.46","article-title":"Viral infections and the common cold","volume":"45","author":"Johnson","year":"1964","journal-title":"Chest"},{"key":"10.1016\/j.jcv.2008.04.002_bib110","doi-asserted-by":"crossref","first-page":"557","DOI":"10.1016\/j.jaci.2005.11.034","article-title":"The September epidemic of asthma hospitalization: school children as disease vectors","volume":"117","author":"Johnston","year":"2006","journal-title":"J Allergy Clin Immunol"},{"key":"10.1016\/j.jcv.2008.04.002_bib111","doi-asserted-by":"crossref","first-page":"267","DOI":"10.1513\/pats.200701-030AW","article-title":"Innate immunity in the pathogenesis of virus-induced asthma exacerbations","volume":"4","author":"Johnston","year":"2007","journal-title":"Proc Am Thorac Soc"},{"key":"10.1016\/j.jcv.2008.04.002_bib112","doi-asserted-by":"crossref","first-page":"237","DOI":"10.1111\/j.1365-2222.1993.tb00316.x","article-title":"Viruses as precipitants of asthma symptoms III. Rhinoviruses: molecular biology and prospects for future intervention","volume":"23","author":"Johnston","year":"1993","journal-title":"Clin Exp Allergy"},{"key":"10.1016\/j.jcv.2008.04.002_bib113","doi-asserted-by":"crossref","first-page":"376","DOI":"10.1136\/bmj.322.7283.376","article-title":"The protective effect of childhood infections","volume":"322","author":"Johnston","year":"2001","journal-title":"Br Med J"},{"key":"10.1016\/j.jcv.2008.04.002_bib114","doi-asserted-by":"crossref","first-page":"1225","DOI":"10.1136\/bmj.310.6989.1225","article-title":"Community study of role of viral infections in exacerbations of asthma in 9\u201311 year old children","volume":"310","author":"Johnston","year":"1995","journal-title":"Br Med J"},{"key":"10.1016\/j.jcv.2008.04.002_bib115","doi-asserted-by":"crossref","first-page":"111","DOI":"10.1128\/JCM.31.1.111-117.1993","article-title":"Use of polymerase chain reaction for diagnosis of picornavirus infection in subjects with and without respiratory symptoms","volume":"31","author":"Johnston","year":"1993","journal-title":"J Clin Microbiol"},{"key":"10.1016\/j.jcv.2008.04.002_bib116","doi-asserted-by":"crossref","first-page":"1392","DOI":"10.1164\/rccm.200604-489OC","article-title":"Chronic rhinoviral infection in lung transplant recipients","volume":"174","author":"Kaiser","year":"2006","journal-title":"Am J Respir Crit Care Med"},{"key":"10.1016\/j.jcv.2008.04.002_bib117","doi-asserted-by":"crossref","first-page":"285","DOI":"10.1128\/JCM.32.2.285-291.1994","article-title":"Nested PCR for specific detection and rapid identification of human picornaviruses","volume":"32","author":"K\u00e4mmerer","year":"1994","journal-title":"J Clin Microbiol"},{"key":"10.1016\/j.jcv.2008.04.002_bib118","doi-asserted-by":"crossref","first-page":"761","DOI":"10.1038\/213761a0","article-title":"Rhinoviruses: a numbering system","volume":"213","author":"Kapikian","year":"1967","journal-title":"Nature"},{"key":"10.1016\/j.jcv.2008.04.002_bib119","doi-asserted-by":"crossref","first-page":"821","DOI":"10.3181\/00379727-110-27662","article-title":"Characterization and classification of ECHO 28-rhinovirus-coryzavirus agents","volume":"110","author":"Ketler","year":"1962","journal-title":"Proc Soc Exp Biol Med"},{"key":"10.1016\/j.jcv.2008.04.002_bib120","doi-asserted-by":"crossref","first-page":"4625","DOI":"10.1128\/JVI.02160-06","article-title":"Human rhinovirus type 54 infection via heparan sulfate is less efficient and strictly dependent on low endosomal pH","volume":"81","author":"Khan","year":"2008","journal-title":"J Virol"},{"key":"10.1016\/j.jcv.2008.04.002_bib121","doi-asserted-by":"crossref","first-page":"314","DOI":"10.1016\/j.jaci.2006.08.041","article-title":"Prevalence of viral respiratory tract infections in children with asthma","volume":"119","author":"Khetsuriani","year":"2007","journal-title":"J Allergy Clin Immunol"},{"key":"10.1016\/j.jcv.2008.04.002_bib122","series-title":"Virus Taxonomy. Seventh Report of the International Committee for the Taxonomy of Viruses","author":"King","year":"2000"},{"key":"10.1016\/j.jcv.2008.04.002_bib123","doi-asserted-by":"crossref","first-page":"817","DOI":"10.1086\/520816","article-title":"Pan-viral screening of respiratory tract infections in adults with and without asthma reveals unexpected human coronavirus and human rhinovirus diversity","volume":"196","author":"Kistler","year":"2007","journal-title":"J Infect Dis"},{"key":"10.1016\/j.jcv.2008.04.002_bib124","doi-asserted-by":"crossref","first-page":"40","DOI":"10.1186\/1743-422X-4-40","article-title":"Genome-wide diversity and selective pressure in the human rhinovirus","volume":"4","author":"Kistler","year":"2007","journal-title":"Virol. J"},{"key":"10.1016\/j.jcv.2008.04.002_bib125","doi-asserted-by":"crossref","first-page":"672","DOI":"10.1111\/j.1365-2222.2005.02244.x","article-title":"Persistence of rhinovirus RNA after asthma exacerbation in children","volume":"35","author":"Kling","year":"2005","journal-title":"Clin Exp Allergy"},{"key":"10.1016\/j.jcv.2008.04.002_bib126","doi-asserted-by":"crossref","first-page":"6249","DOI":"10.1093\/emboj\/18.22.6249","article-title":"Structural studies of two rhinovirus serotypes complexed with fragments of their cellular receptor","volume":"18","author":"Kolatkar","year":"1999","journal-title":"EMBO J"},{"key":"10.1016\/j.jcv.2008.04.002_bib127","doi-asserted-by":"crossref","first-page":"345","DOI":"10.1002\/jmv.1890190407","article-title":"The association of rhinoviruses with lower respiratory tract disease in hospitalized patients","volume":"19","author":"Krilov","year":"1986","journal-title":"J Med Virol"},{"key":"10.1016\/j.jcv.2008.04.002_bib128","doi-asserted-by":"crossref","first-page":"680","DOI":"10.1097\/01.inf.0000226912.88900.a3","article-title":"Role of respiratory viruses in acute upper and lower respiratory tract illness in the first year of life","volume":"25","author":"Kusel","year":"2006","journal-title":"Pediatr Infect Dis J"},{"key":"10.1016\/j.jcv.2008.04.002_bib129","doi-asserted-by":"crossref","first-page":"129","DOI":"10.1099\/vir.0.81137-0","article-title":"Alignment of capsid protein VP1 sequences of all human rhinovirus prototype strains: conserved motifs and functional domains","volume":"87","author":"Laine","year":"2006","journal-title":"J Gen Virol"},{"key":"10.1016\/j.jcv.2008.04.002_bib130","doi-asserted-by":"crossref","first-page":"697","DOI":"10.1099\/vir.0.80445-0","article-title":"Phylogenetic analysis of human rhinovirus capsid protein VP1 and 2A protease coding sequences confirms shared genus-like relationships with human enteroviruses","volume":"86","author":"Laine","year":"2005","journal-title":"J Gen Virol"},{"key":"10.1016\/j.jcv.2008.04.002_bib131","doi-asserted-by":"crossref","first-page":"e929","DOI":"10.1542\/peds.2006-3703","article-title":"Community epidemiology of human metapneumovirus, human coronavirus NL63, and other respiratory viruses in healthy preschool-aged children using parent-collected specimens","volume":"120","author":"Lambert","year":"2007","journal-title":"Pediatrics"},{"key":"10.1016\/j.jcv.2008.04.002_bib132","doi-asserted-by":"crossref","first-page":"1398","DOI":"10.1086\/508551","article-title":"MassTag polymerase-chain-reaction detection of respiratory pathogens, including a new rhinovirus genotype, that caused influenza-like illness in new york state during 2004\u20132005","volume":"194","author":"Lamson","year":"2006","journal-title":"J Infect Dis"},{"key":"10.1016\/j.jcv.2008.04.002_bib133","doi-asserted-by":"crossref","first-page":"221","DOI":"10.1002\/jmv.1890050306","article-title":"Isolation of rhinoviruses and coronaviruses from 38 colds in adults","volume":"5","author":"Larson","year":"1980","journal-title":"J Med Virol"},{"key":"10.1016\/j.jcv.2008.04.002_bib134","doi-asserted-by":"crossref","first-page":"3655","DOI":"10.1128\/JCM.01254-07","article-title":"Clinical features and complete genome characterization of a distinct human rhinovirus genetic cluster, probably representing a previously undetected HRV species, HRV-C, associated with acute respiratory illness in children","volume":"45","author":"Lau","year":"2007","journal-title":"J Clin Microbiol"},{"issue":"4","key":"10.1016\/j.jcv.2008.04.002_bib135","doi-asserted-by":"crossref","first-page":"715","DOI":"10.1007\/s00705-008-0041-x","article-title":"Picornavirales, a proposed order of positive-sense single-stranded RNA viruses with a pseudo-T=3 virion architecture","volume":"153","author":"Le Gall","year":"2008","journal-title":"Arch Virol"},{"key":"10.1016\/j.jcv.2008.04.002_bib136","doi-asserted-by":"crossref","first-page":"135","DOI":"10.1016\/j.antiviral.2005.08.003","article-title":"Insights into the genetic basis for natural phenotypic resistance of human rhinoviruses to pleconaril","volume":"68","author":"Ledford","year":"2005","journal-title":"Antiviral Res"},{"key":"10.1016\/j.jcv.2008.04.002_bib137","doi-asserted-by":"crossref","first-page":"3663","DOI":"10.1128\/JVI.78.7.3663-3674.2004","article-title":"VP1 sequencing of all human rhinovirus serotypes: insights into genus phylogeny and susceptibility to antiviral capsid-binding compounds","volume":"78","author":"Ledford","year":"2004","journal-title":"J Virol"},{"key":"10.1016\/j.jcv.2008.04.002_bib138","doi-asserted-by":"crossref","first-page":"e966","DOI":"10.1371\/journal.pone.0000966","article-title":"A diverse group of previously unrecognized human rhinoviruses are common causes of respiratory illness in infants","volume":"2","author":"Lee","year":"2007","journal-title":"PLoS One"},{"key":"10.1016\/j.jcv.2008.04.002_bib139","doi-asserted-by":"crossref","first-page":"463","DOI":"10.1007\/s10096-006-0166-3","article-title":"Bacterial coinfections in children with viral wheezing","volume":"25","author":"Lehtinen","year":"2006","journal-title":"Eur J Clin Microbiol Inf Dis"},{"key":"10.1016\/j.jcv.2008.04.002_bib140","first-page":"1","article-title":"The childhood origins of asthma (COAST) study","volume":"15","author":"Lemanske","year":"2002","journal-title":"Pediatr Allergy Immunol"},{"key":"10.1016\/j.jcv.2008.04.002_bib141","first-page":"956","article-title":"Viral specimen collection by parents increases response rate in population-based virus studies","volume":"117","author":"Lemanske","year":"2006","journal-title":"J Allergy Clin Immunol"},{"key":"10.1016\/j.jcv.2008.04.002_bib142","doi-asserted-by":"crossref","first-page":"571","DOI":"10.1016\/j.jaci.2005.06.024","article-title":"Rhinovirus illnesses during infancy predict subsequent childhood wheezing","volume":"116","author":"Lemanske","year":"2005","journal-title":"J Allergy Clin Immunol"},{"key":"10.1016\/j.jcv.2008.04.002_bib143","doi-asserted-by":"crossref","first-page":"487","DOI":"10.1006\/mcpr.1994.1070","article-title":"Acute, chronic and persistent enterovirus and poliovirus infections: detection of viral genome by seminested PCR amplification in culture-negative samples","volume":"8","author":"Leparc","year":"1994","journal-title":"Mol Cell Probes"},{"key":"10.1016\/j.jcv.2008.04.002_bib144","doi-asserted-by":"crossref","first-page":"423","DOI":"10.1002\/jmv.1890250406","article-title":"Nasal-secretion leukocyte populatons determined by flow cytometry during acute rhinovirus infection","volume":"25","author":"Levandowski","year":"1988","journal-title":"J Med Virol"},{"key":"10.1016\/j.jcv.2008.04.002_bib145","doi-asserted-by":"crossref","first-page":"365","DOI":"10.1017\/S0022172400066699","article-title":"Observations on the incidence and distribution of the common cold in a rural community during 1948 and 1949","volume":"49","author":"Lidwell","year":"1951","journal-title":"J Hyg"},{"key":"10.1016\/j.jcv.2008.04.002_bib146","doi-asserted-by":"crossref","first-page":"3002","DOI":"10.1128\/JCM.34.12.3002-3006.1996","article-title":"Multicenter evaluation of a commercially available PCR assay for diagnosing enterovirus infection in a panel of cerebrospinal fluid specimens","volume":"34","author":"Lina","year":"1996","journal-title":"J Clin Microbiol"},{"key":"10.1016\/j.jcv.2008.04.002_bib147","doi-asserted-by":"crossref","first-page":"1189","DOI":"10.1086\/522191","article-title":"Improving care for acute respiratory infections: better systems, not better microbiology","volume":"45","author":"Linder","year":"2007","journal-title":"Clin Infect Dis"},{"key":"10.1016\/j.jcv.2008.04.002_bib148","doi-asserted-by":"crossref","first-page":"166","DOI":"10.1128\/JCM.44.1.166-171.2006","article-title":"Detection of rhinoviruses by tissue culture and two independent amplification techniques, nucleic acid sequence-based amplification and reverse transcription-PCR, in children with acute respiratory infections during a winter season","volume":"44","author":"Loens","year":"2006","journal-title":"J Clin Microbiol"},{"key":"10.1016\/j.jcv.2008.04.002_bib149","doi-asserted-by":"crossref","first-page":"262","DOI":"10.1086\/430915","article-title":"Rhinovirus outbreak in a long term care facility for elderly persons associated with unusually high mortality","volume":"41","author":"Louie","year":"2005","journal-title":"Clin Infect Dis"},{"key":"10.1016\/j.jcv.2008.04.002_bib150","doi-asserted-by":"crossref","first-page":"533","DOI":"10.1128\/JCM.01739-07","article-title":"Real-time reverse transcription-PCR assay for comprehensive detection of human rhinoviruses","volume":"46","author":"Lu","year":"2008","journal-title":"J Clin Microbiol"},{"key":"10.1016\/j.jcv.2008.04.002_bib151","unstructured":"Mackay IM, McErlean P, Arden KE, Faux CE, Lambert SB, Nissen MD, et al. Rhinoviruses: support act or main event?. In: Schildgen O, editor. Role of newly detected and emerging viruses in childhood respiratory diseases. Nova science publishers, Inc., in press-a."},{"key":"10.1016\/j.jcv.2008.04.002_bib152","unstructured":"Mackay IM, Arden KE, Nissen MD, Sloots TP. Challenges Facing Real-time PCR Characterization of Acute Respiratory Tract Infections Chapter 8. In: Mackay IM editor. Real-Time PCR in Microbiology: From Diagnosis to Characterization. Caister Academic Press, pp 269\u2013318, in press-b."},{"key":"10.1016\/j.jcv.2008.04.002_bib153","doi-asserted-by":"crossref","first-page":"968","DOI":"10.1086\/521311","article-title":"Human bocavirus; multisystem detection raises questions about infection","volume":"196","author":"Mackay","year":"2007","journal-title":"J Infect Dis"},{"key":"10.1016\/j.jcv.2008.04.002_bib154","series-title":"Real-time PCR in microbiology","first-page":"133","article-title":"Quantification of microorganimsms: not human, not simple, not quick","author":"Mackay","year":"2007"},{"key":"10.1016\/j.jcv.2008.04.002_bib155","first-page":"1","article-title":"The structure and replication of rhinoviruses","volume":"97","author":"Macnaughton","year":"1982","journal-title":"Curr Topics Microbiol Immunol"},{"key":"10.1016\/j.jcv.2008.04.002_bib156","doi-asserted-by":"crossref","first-page":"2965","DOI":"10.1128\/JCM.02436-06","article-title":"Development of a respiratory virus panel test for detection of twenty human respiratory viruses by use of multiplex PCR and a fluid microbead-based assay","volume":"45","author":"Mahony","year":"2007","journal-title":"J Clin Microbiol"},{"key":"10.1016\/j.jcv.2008.04.002_bib157","doi-asserted-by":"crossref","first-page":"1203","DOI":"10.1378\/chest.130.4.1203","article-title":"How viral infections cause exacerbation of airway diseases","volume":"130","author":"Mallia","year":"2006","journal-title":"Chest"},{"key":"10.1016\/j.jcv.2008.04.002_bib158","doi-asserted-by":"crossref","first-page":"116","DOI":"10.1186\/1465-9921-7-116","article-title":"An experimental model of rhinovirus induced chronic obstructive pulmonary disease exacerbations: a pilot study","volume":"7","author":"Mallia","year":"2006","journal-title":"Respir Res"},{"key":"10.1016\/j.jcv.2008.04.002_bib159","doi-asserted-by":"crossref","first-page":"S125","DOI":"10.1016\/j.prrv.2006.04.225","article-title":"Immune responses to viral infections: Relevance for asthma","volume":"7S","author":"Martin","year":"2006","journal-title":"Paediatr Respir Rev"},{"key":"10.1016\/j.jcv.2008.04.002_bib160","doi-asserted-by":"crossref","first-page":"26","DOI":"10.1513\/pats.200607-144JG","article-title":"Gene-environment interactions in asthma","volume":"4","author":"Martinez","year":"2007","journal-title":"Proc Am Thorac Soc"},{"key":"10.1016\/j.jcv.2008.04.002_bib161","doi-asserted-by":"crossref","unstructured":"McErlean P, Shackleton LA, Andrewes E, Webster DR, Lambert SB, Nissen MD, et al. Distinguishing molecular features and clinical characteristics of a putative new rhinovirus species, human rhinovirus C (HRV C). PLoS Apr 2 2008;(4):e1847.","DOI":"10.1371\/journal.pone.0001847"},{"key":"10.1016\/j.jcv.2008.04.002_bib162","doi-asserted-by":"crossref","first-page":"67","DOI":"10.1016\/j.jcv.2007.03.012","article-title":"Characterisation of a newly identified human rhinovirus, HRV-QPM, discovered in infants with bronchiolitis","volume":"39","author":"McErlean","year":"2007","journal-title":"J Clin Virol"},{"key":"10.1016\/j.jcv.2008.04.002_bib163","doi-asserted-by":"crossref","first-page":"740","DOI":"10.1164\/rccm.200208-902SO","article-title":"Acute severe asthma","volume":"168","author":"McFadden","year":"2003","journal-title":"Am J Respir Crit Care Med"},{"key":"10.1016\/j.jcv.2008.04.002_bib164","doi-asserted-by":"crossref","first-page":"733","DOI":"10.1084\/jem.53.5.733","article-title":"A bacteriological study of \u201ccolds\u201d on an isolated tropical island (St John, United States Virgin Islands, West Indies)","volume":"53","author":"Milam","year":"1931","journal-title":"J Exp Med"},{"key":"10.1016\/j.jcv.2008.04.002_bib165","doi-asserted-by":"crossref","first-page":"358","DOI":"10.1016\/S0140-6736(60)90285-3","article-title":"A trial of bacterial vaccines for the common cold in the Royal Air Force","author":"Miller","year":"1960","journal-title":"Lancet"},{"key":"10.1016\/j.jcv.2008.04.002_bib166","doi-asserted-by":"crossref","first-page":"773","DOI":"10.1086\/511821","article-title":"Rhinovirus-associated hospitalizations in young children","volume":"195","author":"Miller","year":"2007","journal-title":"J Infect Dis"},{"key":"10.1016\/j.jcv.2008.04.002_bib167","doi-asserted-by":"crossref","first-page":"472","DOI":"10.1016\/S0022-3476(74)80447-6","article-title":"Greater frequency of viral; respiratory infections in asthmatic children as compared with their nonasthmatic siblings","volume":"85","author":"Minor","year":"1974","journal-title":"J Pediatr"},{"key":"10.1016\/j.jcv.2008.04.002_bib168","doi-asserted-by":"crossref","first-page":"292","DOI":"10.1001\/jama.227.3.292","article-title":"Viruses as precipitants of asthmatic attacks in children","volume":"227","author":"Minor","year":"1974","journal-title":"J Am Med Assoc"},{"key":"10.1016\/j.jcv.2008.04.002_bib169","doi-asserted-by":"crossref","first-page":"1192","DOI":"10.1128\/IAI.10.5.1192-1193.1974","article-title":"Failure of naturally acquired rhinovirus infections to produce temporal immunity to heterologous serotypes","volume":"10","author":"Minor","year":"1974","journal-title":"Infect Immun"},{"key":"10.1016\/j.jcv.2008.04.002_bib170","doi-asserted-by":"crossref","first-page":"e76","DOI":"10.1371\/journal.pmed.0030076","article-title":"Lung infection-a public health priority","volume":"3","author":"Mizgerd","year":"2006","journal-title":"PloS Med"},{"key":"10.1016\/j.jcv.2008.04.002_bib171","doi-asserted-by":"crossref","first-page":"403","DOI":"10.1111\/j.1749-6632.1957.tb46063.x","article-title":"Problems in characterizing and identifying an apparently new virus found in association with mild respiratory disease in recruits","volume":"67","author":"Mogabgab","year":"1957","journal-title":"Ann NY Acad Sci"},{"key":"10.1016\/j.jcv.2008.04.002_bib172","doi-asserted-by":"crossref","first-page":"1987","DOI":"10.1016\/S0149-2918(02)80093-5","article-title":"The seasonality of rhinovirus infection and its implications for clinical recognition","volume":"24","author":"Monto","year":"2002","journal-title":"Clin Therapeut"},{"key":"10.1016\/j.jcv.2008.04.002_bib173","doi-asserted-by":"crossref","first-page":"43","DOI":"10.1093\/infdis\/156.1.43","article-title":"Rhinovirus infections in Tecumseh, Michigan: frequency of illness and number of serotypes","volume":"156","author":"Monto","year":"1987","journal-title":"J Infect Dis"},{"key":"10.1016\/j.jcv.2008.04.002_bib174","doi-asserted-by":"crossref","first-page":"323","DOI":"10.1002\/jmv.1890440403","article-title":"Polymerase chain reaction and sequencing for typing rhinovirus RNA","volume":"44","author":"Mori","year":"1994","journal-title":"J Med Virol"},{"key":"10.1016\/j.jcv.2008.04.002_bib175","doi-asserted-by":"crossref","first-page":"982","DOI":"10.1136\/bmj.307.6910.982","article-title":"Respiratory viruses and exacerbations of asthma in adults","volume":"307","author":"Nicholson","year":"1993","journal-title":"Br Med J"},{"key":"10.1016\/j.jcv.2008.04.002_bib176","doi-asserted-by":"crossref","first-page":"417","DOI":"10.1002\/jmv.2161","article-title":"Human picornavirus and coronavirus RNA in nasopharynx of children without concurrent respiratory symptoms","volume":"66","author":"Nokso-Koivisto","year":"2002","journal-title":"J Med Virol"},{"key":"10.1016\/j.jcv.2008.04.002_bib177","doi-asserted-by":"crossref","first-page":"2779","DOI":"10.1128\/JCM.00669-07","article-title":"MultiCode-PLx system for multiplexed detection of seventeen respiratory viruses","volume":"45","author":"Nolte","year":"2007","journal-title":"J Clin Microbiol"},{"key":"10.1016\/j.jcv.2008.04.002_bib178","doi-asserted-by":"crossref","first-page":"875","DOI":"10.1001\/jama.279.11.875","article-title":"Antibiotic prescribing for children with colds, upper respiratory tract infections and bronchitis","volume":"279","author":"Nyquist","year":"1998","journal-title":"J Am Med Assoc"},{"key":"10.1016\/j.jcv.2008.04.002_bib179","doi-asserted-by":"crossref","first-page":"178","DOI":"10.1542\/peds.101.S1.178","article-title":"Cough illness\/bronchitis \u2013 principles of judicious use of antimicrobial agents","volume":"101","author":"O\u2019Brien","year":"1998","journal-title":"Pediatrics"},{"key":"10.1016\/j.jcv.2008.04.002_bib180","doi-asserted-by":"crossref","first-page":"105","DOI":"10.1016\/S1386-6532(01)00150-0","article-title":"Rapid multiserotype detection of human rhinoviruses on optically coated silicon surfaces","volume":"21","author":"Ostroff","year":"2001","journal-title":"J Clin Virol"},{"key":"10.1016\/j.jcv.2008.04.002_bib181","doi-asserted-by":"crossref","first-page":"179","DOI":"10.1016\/S0166-0934(99)00045-2","article-title":"Rhinovirus identification by BglI digestion of picornavirus RT-PCR amplicons","volume":"80","author":"Papadopoulos","year":"1999","journal-title":"J Virol Methods"},{"key":"10.1016\/j.jcv.2008.04.002_bib182","doi-asserted-by":"crossref","first-page":"1285","DOI":"10.1164\/rccm.200112-118BC","article-title":"Association of rhinovirus infection with increased disease severity in acute bronchiolitis","volume":"165","author":"Papadopoulos","year":"2002","journal-title":"Am J Respir Crit Care Med"},{"key":"10.1016\/j.jcv.2008.04.002_bib183","doi-asserted-by":"crossref","first-page":"100","DOI":"10.1002\/(SICI)1096-9071(199905)58:1<100::AID-JMV16>3.0.CO;2-D","article-title":"Rhinoviruses replicate effectively at lower airway temperatures","volume":"58","author":"Papadopoulos","year":"1999","journal-title":"J Med Virol"},{"key":"10.1016\/j.jcv.2008.04.002_bib184","doi-asserted-by":"crossref","first-page":"328","DOI":"10.1136\/thorax.57.4.328","article-title":"A defective type 1 response to rhinovirus in atopic asthma","volume":"57","author":"Papadopoulos","year":"2002","journal-title":"Thorax"},{"key":"10.1016\/j.jcv.2008.04.002_bib185","doi-asserted-by":"crossref","first-page":"640","DOI":"10.1038\/189640a0","article-title":"A plaque method for assaying some viruses isolated from common colds","volume":"189","author":"Parsons","year":"1961","journal-title":"Nature"},{"key":"10.1016\/j.jcv.2008.04.002_bib186","doi-asserted-by":"crossref","first-page":"391","DOI":"10.1016\/j.antiviral.2006.03.011","article-title":"Rhinovirus chemotherapy","volume":"71","author":"Patick","year":"2006","journal-title":"Antiviral Res"},{"key":"10.1016\/j.jcv.2008.04.002_bib187","doi-asserted-by":"crossref","first-page":"2267","DOI":"10.1128\/AAC.49.6.2267-2275.2005","article-title":"In vitro antiviral activity and single-dose pharmacokinetics in humans of a novel, orally bioavailable inhibitor of human rhinovirus 3C protease","volume":"49","author":"Patick","year":"2005","journal-title":"Antimicrob Agents Chemother"},{"key":"10.1016\/j.jcv.2008.04.002_bib188","doi-asserted-by":"crossref","first-page":"325","DOI":"10.1111\/j.1365-2222.1992.tb03094.x","article-title":"Viruses as precipitants of asthma symptoms. I. Epidemiology","volume":"22","author":"Pattemore","year":"1992","journal-title":"Clin Exp Allergy"},{"key":"10.1016\/j.jcv.2008.04.002_bib189","first-page":"517","article-title":"An epidemiological and bacteriological study of the \u201ccommon cold\u201d in an isolated arctic community (Spitsbergen)","volume":"17","author":"Paul","year":"1933","journal-title":"Am J Hyg"},{"key":"10.1016\/j.jcv.2008.04.002_bib190","first-page":"36","article-title":"Classification of the \u201c2060\u201d virus as ECHO 28 and further study of its properties","volume":"73","author":"Pelon","year":"1961","journal-title":"Am J Hyg"},{"key":"10.1016\/j.jcv.2008.04.002_bib191","doi-asserted-by":"crossref","first-page":"262","DOI":"10.3181\/00379727-94-22915","article-title":"A cytopathogenic agent isolated from naval recruits with mild respiratory illnesses","volume":"94","author":"Pelon","year":"1957","journal-title":"Proc Soc Exp Biol Med"},{"key":"10.1016\/j.jcv.2008.04.002_bib192","doi-asserted-by":"crossref","first-page":"382","DOI":"10.1086\/525542","article-title":"Rhinovirus transmission within families with children: incidence of symptomatic and asymptomatic infections","volume":"197","author":"Peltola","year":"2008","journal-title":"J Infect Dis"},{"key":"10.1016\/j.jcv.2008.04.002_bib193","doi-asserted-by":"crossref","first-page":"1605","DOI":"10.1002\/jcc.20084","article-title":"UCSF chimera-A visualization system for exploratory research and analysis","volume":"25","author":"Pettersen","year":"2004","journal-title":"J Comput Chem"},{"key":"10.1016\/j.jcv.2008.04.002_bib194","doi-asserted-by":"crossref","first-page":"2002","DOI":"10.1128\/JVI.63.5.2002-2007.1989","article-title":"Conformational change in the floor of the human rhinovirus canyon blocks adsorption to HeLa cell receptors","volume":"63","author":"Pevear","year":"1989","journal-title":"J Virol"},{"key":"10.1016\/j.jcv.2008.04.002_bib195","doi-asserted-by":"crossref","first-page":"447","DOI":"10.1093\/oxfordjournals.aje.a120835","article-title":"Rhinovirus infections in a student population: Isolation of the five new serotypes","volume":"87","author":"Phillips","year":"1968","journal-title":"Am J Epidemiol"},{"key":"10.1016\/j.jcv.2008.04.002_bib196","doi-asserted-by":"crossref","first-page":"1791","DOI":"10.1128\/JCM.35.7.1791-1793.1997","article-title":"Detection of rhinovirus in sinus brushings of patients with acute community-acquired sinusitis by reverse transcription-PCR","volume":"35","author":"Pitk\u00e4ranta","year":"1997","journal-title":"J Clin Microbiol"},{"key":"10.1016\/j.jcv.2008.04.002_bib197","doi-asserted-by":"crossref","first-page":"647","DOI":"10.1016\/j.ijporl.2005.08.018","article-title":"Presence of viral and bacterial pathogens in the nasopharynx of otitis-prone children. A prospective study","volume":"70","author":"Pitk\u00e4ranta","year":"2005","journal-title":"Int J Pediatr Otorhinol"},{"key":"10.1016\/j.jcv.2008.04.002_bib198","doi-asserted-by":"crossref","first-page":"291","DOI":"10.1542\/peds.102.2.291","article-title":"Detection of rhinovirus, respiratory syncytial virus and coronavirus infections in acute otitis media by reverse-transcriptase polymerase chain reaction","volume":"102","author":"Pitk\u00e4ranta","year":"1998","journal-title":"Pediatrics"},{"key":"10.1016\/j.jcv.2008.04.002_bib199","doi-asserted-by":"crossref","first-page":"1178","DOI":"10.1164\/ajrccm.158.4.9712082","article-title":"Asthma and natural colds","volume":"158","author":"Pizzichini","year":"1998","journal-title":"Am J Respir Crit Care Med"},{"key":"10.1016\/j.jcv.2008.04.002_bib200","doi-asserted-by":"crossref","first-page":"892","DOI":"10.1073\/pnas.42.12.892","article-title":"The isolation of a new virus associated with respiratory clinical disease in humans","volume":"42","author":"Price","year":"1956","journal-title":"Proc Natl Acad Sci USA"},{"key":"10.1016\/j.jcv.2008.04.002_bib201","first-page":"685","article-title":"Picornaviridae: the viruses and their replication","volume":"vol. 1","author":"Racaniello","year":"2001"},{"key":"10.1016\/j.jcv.2008.04.002_bib202","doi-asserted-by":"crossref","first-page":"785","DOI":"10.1164\/ajrccm.159.3.9801052","article-title":"Rhinovirus and respiratory syncytial virus in wheezing children requiring emergency care","volume":"159","author":"Rakes","year":"1999","journal-title":"Am J Respir Crit Care Med"},{"key":"10.1016\/j.jcv.2008.04.002_bib203","unstructured":"Rathe J. Resolution of all known HRV-A and HRV-B complete genome sequences, and their relationship to a potential new species, HRV-C. XV European Study Group on the Molecular Biology of Picornaviruses meeting, EUROPIC 2008."},{"key":"10.1016\/j.jcv.2008.04.002_bib204","doi-asserted-by":"crossref","first-page":"1314","DOI":"10.1086\/368411","article-title":"Asthma exacerbations in children are associated with rhinovirus but not human metapneumovirus infection","volume":"187","author":"Rawlinson","year":"2003","journal-title":"J Infect Dis"},{"key":"10.1016\/j.jcv.2008.04.002_bib205","doi-asserted-by":"crossref","first-page":"691","DOI":"10.1128\/JCM.35.3.691-696.1997","article-title":"Aseptic meningitis and encephalitis: the role of PCR in the diagnostic laboratory","volume":"35","author":"Read","year":"1997","journal-title":"J Clin Microbiol"},{"key":"10.1016\/j.jcv.2008.04.002_bib206","doi-asserted-by":"crossref","first-page":"515","DOI":"10.7326\/0003-4819-57-4-515","article-title":"Clinical and laboratory findings in cases of respirtaory illness caused by coryzaviruses","volume":"57","author":"Reilly","year":"1962","journal-title":"Ann Intern Med"},{"key":"10.1016\/j.jcv.2008.04.002_bib207","doi-asserted-by":"crossref","first-page":"1754","DOI":"10.1086\/524312","article-title":"A recently identified rhinovirus genotype is associated with severe respiratory-tract infection in children in Germany","volume":"196","author":"Renwick","year":"2007","journal-title":"J Infect Dis"},{"key":"10.1016\/j.jcv.2008.04.002_bib208","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1097\/INF.0b013e31815b4935","article-title":"The impact of dual viral infection in infants admitted to a pediatric intensive care unit associated with severe bronchiolitis","volume":"27","author":"Richard","year":"2008","journal-title":"Pediatr Infect Dis J"},{"key":"10.1016\/j.jcv.2008.04.002_bib209","doi-asserted-by":"crossref","first-page":"903","DOI":"10.1016\/j.ijporl.2004.02.005","article-title":"Rhinovirus in adenoid tissue","volume":"68","author":"Rihkanen","year":"2004","journal-title":"Int J Pediatr Otorhinol"},{"key":"10.1016\/j.jcv.2008.04.002_bib210","first-page":"140","article-title":"Viral respiratory infections in asthmatic children staying in a mountain resort","volume":"63","author":"Roldaan","year":"1982","journal-title":"Eur J Respir Dis"},{"key":"10.1016\/j.jcv.2008.04.002_bib211","doi-asserted-by":"crossref","first-page":"173","DOI":"10.1128\/MMBR.29.2.173-184.1965","article-title":"Subclassification of picornaviruses","volume":"29","author":"Rosen","year":"1965","journal-title":"Bacteriol Rev"},{"key":"10.1016\/j.jcv.2008.04.002_bib212","doi-asserted-by":"crossref","first-page":"183","DOI":"10.1093\/oxfordjournals.aje.a121245","article-title":"Epidemiology of the common cold in military recruits with emphasis on infections by rhinovirus types 1A, 2, and two unclassified rhinoviruses","volume":"93","author":"Rosenbaum","year":"1971","journal-title":"Am J Epidemiol"},{"key":"10.1016\/j.jcv.2008.04.002_bib213","doi-asserted-by":"crossref","first-page":"181","DOI":"10.1542\/peds.101.S1.181","article-title":"The common cold \u2013 principles of judicious use of antimicrobial agents","volume":"101","author":"Rosenstein","year":"1998","journal-title":"Pediatrics"},{"key":"10.1016\/j.jcv.2008.04.002_bib214","doi-asserted-by":"crossref","first-page":"1712","DOI":"10.1002\/pro.5560031010","article-title":"Viral cell recognition and entry","volume":"3","author":"Rossmann","year":"1994","journal-title":"Protein Science"},{"key":"10.1016\/j.jcv.2008.04.002_bib215","doi-asserted-by":"crossref","first-page":"145","DOI":"10.1038\/317145a0","article-title":"Structure of a human common cold virus and functional relationship to other picornaviruses","volume":"317","author":"Rossmann","year":"1985","journal-title":"Nature"},{"key":"10.1016\/j.jcv.2008.04.002_bib216","doi-asserted-by":"crossref","first-page":"239","DOI":"10.1006\/viro.2000.0258","article-title":"Cell recognition and entry by rhino- and enteroviruses","volume":"269","author":"Rossmann","year":"2000","journal-title":"Virology"},{"key":"10.1016\/j.jcv.2008.04.002_bib217","doi-asserted-by":"crossref","first-page":"324","DOI":"10.1016\/S0966-842X(02)02383-1","article-title":"Picornavirus-receptor interactions","volume":"10","author":"Rossmann","year":"2002","journal-title":"Trends Microbiol"},{"key":"10.1016\/j.jcv.2008.04.002_bib218","doi-asserted-by":"crossref","first-page":"83","DOI":"10.1016\/S0166-3542(01)00206-6","article-title":"Treatment of picornavirus infections","volume":"53","author":"Rotbart","year":"2002","journal-title":"Antiviral Res"},{"key":"10.1016\/j.jcv.2008.04.002_bib219","doi-asserted-by":"crossref","first-page":"913","DOI":"10.1001\/archfami.9.9.913","article-title":"Picornavirus infections: a primer for the practitioner","volume":"9","author":"Rotbart","year":"2000","journal-title":"Arch Family Med"},{"key":"10.1016\/j.jcv.2008.04.002_bib220","doi-asserted-by":"crossref","first-page":"957","DOI":"10.1128\/JVI.50.3.957-959.1984","article-title":"Systematic nomenclature of picornavirus proteins","volume":"50","author":"Rueckert","year":"1984","journal-title":"J Virol"},{"key":"10.1016\/j.jcv.2008.04.002_bib221","series-title":"18th International Conference proceedings thereof on Antiviral Research","article-title":"A new oral rhinovirus inhibitor BTA798","author":"Ryan","year":"2005"},{"key":"10.1016\/j.jcv.2008.04.002_bib222","doi-asserted-by":"crossref","first-page":"333","DOI":"10.1099\/0022-1317-83-2-333","article-title":"Genetic clustering of all 102 human rhinovirus prototype strains: serotype 87 is close to human enterovirus 70","volume":"83","author":"Savolainen","year":"2002","journal-title":"J Gen Virol"},{"key":"10.1016\/j.jcv.2008.04.002_bib223","doi-asserted-by":"crossref","first-page":"2271","DOI":"10.1099\/vir.0.79897-0","article-title":"Sequence analysis of human rhinoviruses in the RNA-dependent RNA polymerase coding region reveals within-species variation","volume":"85","author":"Savolainen","year":"2004","journal-title":"J Gen Virol"},{"key":"10.1016\/j.jcv.2008.04.002_bib224","doi-asserted-by":"crossref","first-page":"171","DOI":"10.1542\/peds.101.S1.171","article-title":"Pharyngitis \u2013 principles of judicious use of antimicrobial agents","volume":"101","author":"Schwartz","year":"1998","journal-title":"Pediatrics"},{"key":"10.1016\/j.jcv.2008.04.002_bib225","doi-asserted-by":"crossref","first-page":"1618","DOI":"10.1164\/ajrccm.164.9.2105011","article-title":"Respiratory viruses, symptoms, and inflammatory markers in acute exacerbations and stable chornic obstrcutive pulmonary disease","volume":"164","author":"Seemungal","year":"2001","journal-title":"Am J Respir Crit Care Med"},{"key":"10.1016\/j.jcv.2008.04.002_bib226","first-page":"60","article-title":"Reproducible plaquing system for rhinovirus serotypes in HeLa cells \u2013 agarose suspension","volume":"22","author":"Sethi","year":"1978","journal-title":"Acta Virol"},{"key":"10.1016\/j.jcv.2008.04.002_bib227","doi-asserted-by":"crossref","first-page":"2630","DOI":"10.1021\/nl061666f","article-title":"Rapid and sensitive detection of respiratory virus molecular signatures using a silver nanorod array SERS substrate","volume":"6","author":"Shanmukh","year":"2006","journal-title":"Nano Lett"},{"key":"10.1016\/j.jcv.2008.04.002_bib228","doi-asserted-by":"crossref","first-page":"4","DOI":"10.1157\/13099088","article-title":"Role of viruses and atypical bacteria in asthma exacerbations among children in Oporto (Portugal)","volume":"35","author":"Silva","year":"2007","journal-title":"Allergologia et immunopathologia"},{"key":"10.1016\/j.jcv.2008.04.002_bib229","doi-asserted-by":"crossref","first-page":"2111","DOI":"10.1093\/nar\/13.6.2111","article-title":"Human rhinovirus 2: Complete nucleotide sequence and proteolytic processing signals in the capsid protein region","volume":"13","author":"Skern","year":"1985","journal-title":"Nucleic Acids Res"},{"key":"10.1016\/j.jcv.2008.04.002_bib230","doi-asserted-by":"crossref","first-page":"2258","DOI":"10.1001\/jama.269.17.2258","article-title":"Over-the-counter cold medications: a critical review of clinical trials between 1950 and 1991","volume":"269","author":"Smith","year":"1993","journal-title":"J Am Med Assoc"},{"key":"10.1016\/j.jcv.2008.04.002_bib231","doi-asserted-by":"crossref","first-page":"552","DOI":"10.1542\/peds.55.4.552","article-title":"The misuse of antibiotics for treatment of upper respiratory tract infections in children","volume":"55","author":"Soyka","year":"1975","journal-title":"Pediatrics"},{"key":"10.1016\/j.jcv.2008.04.002_bib232","doi-asserted-by":"crossref","first-page":"577","DOI":"10.1249\/mss.0b013e31802e851a","article-title":"Incidence, etiology, and symptomatology of upper respiratory illness in elite athletes","volume":"39","author":"Spence","year":"2007","journal-title":"Med Sci Sports Exer"},{"key":"10.1016\/j.jcv.2008.04.002_bib233","doi-asserted-by":"crossref","first-page":"7859","DOI":"10.1093\/nar\/12.20.7859","article-title":"The complete nucleotide sequence of a common cold virus: human rhinovirus 14","volume":"12","author":"Stanway","year":"1984","journal-title":"Nucleic Acids Res"},{"key":"10.1016\/j.jcv.2008.04.002_bib234","doi-asserted-by":"crossref","first-page":"849","DOI":"10.1016\/0092-8674(89)90689-2","article-title":"A cell adhesion molecule, ICAM-1, is the major surface receptor for rhinoviruses","volume":"56","author":"Staunton","year":"1989","journal-title":"Cell"},{"key":"10.1016\/j.jcv.2008.04.002_bib235","doi-asserted-by":"crossref","first-page":"129","DOI":"10.1128\/JCM.39.1.129-133.2001","article-title":"Early detection of acute rhinovirus infections by a rapid reverse transcription-PCR assay","volume":"39","author":"Steininger","year":"2001","journal-title":"J Clin Microbiol"},{"key":"10.1016\/j.jcv.2008.04.002_bib236","doi-asserted-by":"crossref","first-page":"47","DOI":"10.1093\/protein\/7.1.47","article-title":"The BC loop in poliovirus coat protein VP1: an ideal acceptor site for major insertions","volume":"7","author":"Stirk","year":"1994","journal-title":"Protein Eng"},{"key":"10.1016\/j.jcv.2008.04.002_bib237","doi-asserted-by":"crossref","first-page":"45","DOI":"10.1093\/oxfordjournals.aje.a121048","article-title":"Rhinovirus infections of children in hospital; isolation of three possibly new rhinoviruse seroptypes","volume":"90","author":"Stott","year":"1969","journal-title":"Am J Epidemiol"},{"key":"10.1016\/j.jcv.2008.04.002_bib238","doi-asserted-by":"crossref","first-page":"1259","DOI":"10.1136\/bmj.299.6710.1259","article-title":"Hay fever, hygiene, and household size","volume":"299","author":"Strachan","year":"1989","journal-title":"Br Med J"},{"key":"10.1016\/j.jcv.2008.04.002_bib239","doi-asserted-by":"crossref","first-page":"38","DOI":"10.1093\/clinids\/17.1.38","article-title":"Association of rhinovirus infection with poor bacteriologic outcome of bacterial-viral otitis media","volume":"17","author":"Sung","year":"1993","journal-title":"Clin Infect Dis"},{"key":"10.1016\/j.jcv.2008.04.002_bib240","doi-asserted-by":"crossref","first-page":"292","DOI":"10.1016\/j.jcv.2005.08.009","article-title":"Rhinovirus\/enterovirus RNA in tonsillar tissue of children with tonsillar disease","volume":"35","author":"Suvilehto","year":"2006","journal-title":"J Clin Virol"},{"key":"10.1016\/j.jcv.2008.04.002_bib241","doi-asserted-by":"crossref","first-page":"272","DOI":"10.1097\/01.mlg.0000249922.37381.1e","article-title":"Identification of viruses in patients with postviral olfactory dysfunction","volume":"117","author":"Suzuki","year":"2007","journal-title":"The Laryngoscope"},{"key":"10.1016\/j.jcv.2008.04.002_bib242","doi-asserted-by":"crossref","first-page":"1596","DOI":"10.1093\/molbev\/msm092","article-title":"Molecular evolutionary genetics analysis (MEGA) software version 4.0","volume":"24","author":"Tamura","year":"2007","journal-title":"Mol Biol Evol"},{"key":"10.1016\/j.jcv.2008.04.002_bib243","unstructured":"Tapparel C, Junier T, Cordey S, M\u00fchlemann K, Van Belle S, Turin L, Zdobnov E, Kaiser L. Genome analysis of circulating picornavirus reveals rhinovirus recombination and a new enterovirus serotype. XV European Study Group on the Molecular Biology of Picornaviruses meeting, EUROPIC 2008."},{"key":"10.1016\/j.jcv.2008.04.002_bib244","doi-asserted-by":"crossref","first-page":"224","DOI":"10.1186\/1471-2164-8-224","article-title":"New complete genome sequences of human rhinoviruses shed light on their phylogeny and genomic features","volume":"10","author":"Tapparel","year":"2007","journal-title":"BMC Genomics"},{"key":"10.1016\/j.jcv.2008.04.002_bib245","first-page":"S262","article-title":"Laboratory and volunteer studies on some viruses isolated from common colds (Rhinoviruses)","volume":"88","author":"Taylor-Robinson","year":"1963","journal-title":"Am Rev Resp Dis"},{"key":"10.1016\/j.jcv.2008.04.002_bib246","doi-asserted-by":"crossref","first-page":"452","DOI":"10.1016\/S0140-6736(62)91418-6","article-title":"Serotypes of viruses (rhinoviruses) isolated from common colds","author":"Taylor-Robinson","year":"1962","journal-title":"Lancet"},{"key":"10.1016\/j.jcv.2008.04.002_bib247","doi-asserted-by":"crossref","first-page":"226","DOI":"10.1097\/00006454-198405000-00009","article-title":"Bacteriology and treatment of purulent nasopharyngitis: a double-blind, placebo-controlled evaluation","volume":"3","author":"Todd","year":"1984","journal-title":"Pediatr Infect Dis J"},{"key":"10.1016\/j.jcv.2008.04.002_bib248","doi-asserted-by":"crossref","first-page":"4907","DOI":"10.1073\/pnas.86.13.4907","article-title":"cDNA cloning reveals that the major group rhinovirus receptor on HeLa cells is intercellular adhesion molecule 1","volume":"86","author":"Tomassini","year":"1989","journal-title":"Proc Natl Acad Sci USA"},{"key":"10.1016\/j.jcv.2008.04.002_bib249","doi-asserted-by":"crossref","first-page":"3111","DOI":"10.1099\/0022-1317-70-11-3111","article-title":"Typing of human rhinoviruses based on sequence variations in the 5\u2019 non-coding region","volume":"70","author":"Torgersen","year":"1989","journal-title":"J Gen Virol"},{"key":"10.1016\/j.jcv.2008.04.002_bib250","doi-asserted-by":"crossref","first-page":"790","DOI":"10.3928\/0090-4481-19981201-06","article-title":"The common cold","volume":"27","author":"Turner","year":"1998","journal-title":"Pediatr Ann"},{"key":"10.1016\/j.jcv.2008.04.002_bib251","doi-asserted-by":"crossref","first-page":"1797","DOI":"10.1001\/jama.281.19.1797","article-title":"Efficacy of Tremacamra, a soluble intercellular adhesion molecule 1, for experimental rhinovirus infection","volume":"281","author":"Turner","year":"2007","journal-title":"J Am Med Assoc"},{"key":"10.1016\/j.jcv.2008.04.002_bib252","doi-asserted-by":"crossref","first-page":"840","DOI":"10.1086\/513922","article-title":"Association between interleukin-8 concentration in nasal secretions and severity of experimental rhinovirus colds","volume":"26","author":"Turner","year":"1998","journal-title":"Clin Infect Dis"},{"key":"10.1016\/j.jcv.2008.04.002_bib253","doi-asserted-by":"crossref","first-page":"105","DOI":"10.1016\/0166-3542(92)90032-Z","article-title":"A view from the common cold unit","volume":"18","author":"Tyrrell","year":"1992","journal-title":"Antiviral Res"},{"key":"10.1016\/j.jcv.2008.04.002_bib254","doi-asserted-by":"crossref","first-page":"320","DOI":"10.1016\/S0140-6736(62)90107-1","article-title":"The cultivation in human-embryo cells of a virus (D.C.) causing colds in man","volume":"280","author":"Tyrrell","year":"1962","journal-title":"Lancet"},{"key":"10.1016\/j.jcv.2008.04.002_bib255","doi-asserted-by":"crossref","first-page":"393","DOI":"10.1136\/bmj.1.5223.393","article-title":"Some further virus isolations from common colds","author":"Tyrrell","year":"1961","journal-title":"Br Med J"},{"key":"10.1016\/j.jcv.2008.04.002_bib256","doi-asserted-by":"crossref","first-page":"235","DOI":"10.1016\/S0140-6736(60)90166-5","article-title":"Some virus isolations from common colds. I. Experiments employing human volunteers","author":"Tyrrell","year":"1960","journal-title":"Lancet"},{"key":"10.1016\/j.jcv.2008.04.002_bib257","series-title":"Cold wars: The fight against the common cold","author":"Tyrrell","year":"2002"},{"key":"10.1016\/j.jcv.2008.04.002_bib258","doi-asserted-by":"crossref","first-page":"239","DOI":"10.1016\/S0140-6736(60)90168-9","article-title":"Some virus isolations from common colds. III. Cytopathic effects in tissue cultures","volume":"i","author":"Tyrrell","year":"1960","journal-title":"Lancet"},{"key":"10.1016\/j.jcv.2008.04.002_bib259","doi-asserted-by":"crossref","first-page":"814","DOI":"10.1016\/0042-6822(91)90098-V","article-title":"The major and minor group receptor families contain all but one human rhinovirus serotype","volume":"180","author":"Uncapher","year":"1991","journal-title":"Virol"},{"key":"10.1016\/j.jcv.2008.04.002_bib260","doi-asserted-by":"crossref","first-page":"443","DOI":"10.1136\/jcp.25.5.443","article-title":"Virological studies of sudden, unexplained infant deaths in Glasgow 1967\u20131970","volume":"25","author":"Urquhart","year":"1972","journal-title":"J Clin Pathol"},{"key":"10.1016\/j.jcv.2008.04.002_bib261","doi-asserted-by":"crossref","first-page":"28","DOI":"10.1136\/bmj.4.5726.28","article-title":"Rhinoviraemia","volume":"4","author":"Urquhart","year":"1970","journal-title":"Br Med J"},{"key":"10.1016\/j.jcv.2008.04.002_bib262","doi-asserted-by":"crossref","first-page":"1571","DOI":"10.1086\/379200","article-title":"Prevalence and clinical symptoms of human metapneumovirus infection in hospitalized patients","volume":"188","author":"van den Hoogen","year":"2003","journal-title":"J Infect Dis"},{"key":"10.1016\/j.jcv.2008.04.002_bib263","doi-asserted-by":"crossref","first-page":"955","DOI":"10.1016\/j.jaci.2006.01.006","article-title":"Viral specimen collection by parents increases response rate in population-based virus studies","volume":"117","author":"van der Zalm","year":"2006","journal-title":"J Allergy Clin Immunol"},{"key":"10.1016\/j.jcv.2008.04.002_bib264","doi-asserted-by":"crossref","first-page":"801","DOI":"10.1111\/j.1469-0691.2005.01234.x","article-title":"Community-acquired pathogens associated with prolonged coughing in children: a prospective cohort study","volume":"11","author":"Versteegh","year":"2005","journal-title":"Clin Microbiol Infect"},{"key":"10.1016\/j.jcv.2008.04.002_bib265","doi-asserted-by":"crossref","first-page":"574","DOI":"10.1097\/00006454-200106000-00006","article-title":"Epidemiology of documented viral respiratory infections and acute otitis media in a cohort of children followed from two to twenty-four months of age","volume":"20","author":"Vesa","year":"2001","journal-title":"Pediatr Infect Dis J"},{"key":"10.1016\/j.jcv.2008.04.002_bib266","doi-asserted-by":"crossref","first-page":"540","DOI":"10.1016\/S0022-3476(88)80164-1","article-title":"Frequency and severity of infection in day care","volume":"112","author":"Wald","year":"1988","journal-title":"J Pediatr"},{"key":"10.1016\/j.jcv.2008.04.002_bib267","doi-asserted-by":"crossref","first-page":"588","DOI":"10.7326\/0003-4819-123-8-199510150-00004","article-title":"A rhinovirus outbreak among residents of a long-term care facility","volume":"123","author":"Wald","year":"1995","journal-title":"Ann Intern Med"},{"key":"10.1016\/j.jcv.2008.04.002_bib268","doi-asserted-by":"crossref","first-page":"15687","DOI":"10.1073\/pnas.242579699","article-title":"Microarray-based detection and genotyping of viral pathogens","volume":"99","author":"Wang","year":"2002","journal-title":"Proc Natl Acad Sci USA"},{"key":"10.1016\/j.jcv.2008.04.002_bib269","doi-asserted-by":"crossref","first-page":"19","DOI":"10.2174\/138920307779941523","article-title":"Human rhinovirus 3C protease as a potential target for the development of antiviral agents","volume":"8","author":"Wang","year":"2007","journal-title":"Curr Protein Peptide Sci"},{"key":"10.1016\/j.jcv.2008.04.002_bib270","doi-asserted-by":"crossref","first-page":"586","DOI":"10.1016\/j.jaci.2007.04.046","article-title":"IFN-g-induced protein 10 is a novel biomarker of rhinovirus-induced asthma exacerbations","volume":"120","author":"Wark","year":"2007","journal-title":"J Allergy Clin Immunol"},{"key":"10.1016\/j.jcv.2008.04.002_bib271","doi-asserted-by":"crossref","first-page":"937","DOI":"10.1084\/jem.20041901","article-title":"Asthmatic bronchial epithelial cells have a deficient innate immune response to infection with rhinovirus","volume":"201","author":"Wark","year":"2005","journal-title":"J Exp Med"},{"key":"10.1016\/j.jcv.2008.04.002_bib272","doi-asserted-by":"crossref","first-page":"1763","DOI":"10.1001\/jama.256.13.1763","article-title":"Sites of rhinovirus recovery after point inoculation of the upper airway","volume":"256","author":"Winther","year":"1986","journal-title":"J Am Med Assoc"},{"key":"10.1016\/j.jcv.2008.04.002_bib273","doi-asserted-by":"crossref","first-page":"644","DOI":"10.1002\/jmv.20588","article-title":"Picornavirus infections in children diagnosed by RT-PCR during longitudinal surveillance with weekly sampling: association with symptomatic illness and effect of season","volume":"78","author":"Winther","year":"2006","journal-title":"J Med Virol"},{"key":"10.1016\/j.jcv.2008.04.002_bib274","doi-asserted-by":"crossref","first-page":"1606","DOI":"10.1002\/jmv.20956","article-title":"Environmental contamination with rhinovirus and transfer to fingers of healthy individuals by daily life activity","volume":"79","author":"Winther","year":"2007","journal-title":"J Med Virol"},{"key":"10.1016\/j.jcv.2008.04.002_bib275","doi-asserted-by":"crossref","first-page":"2126","DOI":"10.1128\/JCM.02553-06","article-title":"Comparison of detection of rhinovirus by polymerase chain reaction and viral culture in human nasal wash specimens from subjects with and without clinical symptoms of respiratory illness","volume":"45","author":"Wright","year":"2007","journal-title":"J Clin Microbiol"},{"key":"10.1016\/j.jcv.2008.04.002_bib276","doi-asserted-by":"crossref","first-page":"1037","DOI":"10.1164\/rccm.200502-315OC","article-title":"Rhinovirus viremia in children with respiratory infections","volume":"172","author":"Xatzipsalti","year":"2005","journal-title":"Am J Respir Crit Care Med"},{"key":"10.1016\/j.jcv.2008.04.002_bib277","doi-asserted-by":"crossref","first-page":"277","DOI":"10.1513\/pats.200702-033AW","article-title":"Microbial manipulation of immune function for asthma prevention. Inferences from clinical trials","volume":"4","author":"Yoo","year":"2007","journal-title":"Proceedings of the American Thoracic Society"}],"container-title":["Journal of Clinical Virology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1386653208001303?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1386653208001303?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2023,5,18]],"date-time":"2023-05-18T14:51:48Z","timestamp":1684421508000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1386653208001303"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2008,8]]},"references-count":277,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2008,8]]}},"alternative-id":["S1386653208001303"],"URL":"https:\/\/doi.org\/10.1016\/j.jcv.2008.04.002","relation":{},"ISSN":["1386-6532"],"issn-type":[{"value":"1386-6532","type":"print"}],"subject":[],"published":{"date-parts":[[2008,8]]}}}