{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,14]],"date-time":"2026-02-14T09:36:44Z","timestamp":1771061804678,"version":"3.50.1"},"reference-count":24,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2015,8,1]],"date-time":"2015-08-01T00:00:00Z","timestamp":1438387200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":["journalofclinicalvirology.com","clinicalkey.jp","clinicalkey.com","clinicalkey.es","clinicalkey.com.au","clinicalkey.fr","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Journal of Clinical Virology"],"published-print":{"date-parts":[[2015,8]]},"DOI":"10.1016\/j.jcv.2015.06.097","type":"journal-article","created":{"date-parts":[[2015,6,24]],"date-time":"2015-06-24T23:15:15Z","timestamp":1435187715000},"page":"176-178","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":6,"special_numbering":"C","title":["Ganciclovir-resistant HHV-6 encephalitis that progressed rapidly after bone marrow transplantation"],"prefix":"10.1016","volume":"69","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-5332-1316","authenticated-orcid":false,"given":"Osamu","family":"Imataki","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Makiko","family":"Uemura","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.jcv.2015.06.097_bib0005","doi-asserted-by":"crossref","first-page":"1065","DOI":"10.7326\/0003-4819-124-12-199606150-00007","article-title":"Human herpesvirus-6 in transplantation: an emerging pathogen","volume":"124","author":"Singh","year":"1996","journal-title":"Ann. Intern. Med."},{"key":"10.1016\/j.jcv.2015.06.097_bib0010","doi-asserted-by":"crossref","first-page":"66","DOI":"10.1111\/j.1365-2141.2004.05254.x","article-title":"Impact of human herpesvirus-6 after haematopoietic stem cell transplantation","volume":"128","author":"Hentrich","year":"2005","journal-title":"Br. J. Haematol."},{"key":"10.1016\/j.jcv.2015.06.097_bib0015","doi-asserted-by":"crossref","first-page":"33","DOI":"10.1111\/j.1399-3062.2011.00662.x","article-title":"Safety of pre-engraftment prophylactic foscarnet administration after allogeneic stem cell transplantation","volume":"14","author":"Ishiyama","year":"2012","journal-title":"Trans. Infect. Dis."},{"key":"10.1016\/j.jcv.2015.06.097_bib0020","doi-asserted-by":"crossref","first-page":"257","DOI":"10.1038\/bmt.2012.121","article-title":"Foscarnet against human herpesvirus (HHV)-6 reactivation after allo-SCT: breakthrough HHV-6 encephalitis following antiviral prophylaxis","volume":"48","author":"Ogata","year":"2013","journal-title":"Bone Marrow Transplant."},{"key":"10.1016\/j.jcv.2015.06.097_bib0025","doi-asserted-by":"crossref","first-page":"164","DOI":"10.1016\/j.jcv.2011.06.008","article-title":"Deciphering the clinical impact of acute human herpesvirus 6 (HHV-6) infections","volume":"52","author":"Agut","year":"2011","journal-title":"J. Clin. Virol."},{"key":"10.1016\/j.jcv.2015.06.097_bib0030","doi-asserted-by":"crossref","first-page":"S52","DOI":"10.1016\/S1386-6532(06)70012-9","article-title":"Human herpesvirus 6 and central nervous system disease in hematopoietic cell transplantation","volume":"37","author":"Zerr","year":"2006","journal-title":"J. Clin. Virol."},{"key":"10.1016\/j.jcv.2015.06.097_bib0035","doi-asserted-by":"crossref","first-page":"5458","DOI":"10.1200\/JCO.2007.11.9958","article-title":"Japan Clinical Oncology Group Study JCOG9801. VCAP-AMP-VECP compared with biweekly CHOP for adult T-cell leukemia-lymphoma: Japan Clinical Oncology Group Study JCOG9801","volume":"25","author":"Tsukasaki","year":"2007","journal-title":"J. Clin. Oncol."},{"key":"10.1016\/j.jcv.2015.06.097_bib0040","doi-asserted-by":"crossref","first-page":"568","DOI":"10.1097\/00007890-200202270-00015","article-title":"Response-oriented preemptive therapy against cytomegalovirus disease with low-dose ganciclovir: a prospective evaluation","volume":"73","author":"Kanda","year":"2002","journal-title":"Transplantation"},{"key":"10.1016\/j.jcv.2015.06.097_bib0045","doi-asserted-by":"crossref","first-page":"1080","DOI":"10.1016\/j.bbmt.2011.12.579","article-title":"Early human herpesvirus type 6 reactivation after allogeneic stem cell transplantation: a large-scale clinical study","volume":"18","author":"Dulery","year":"2012","journal-title":"Biol. Blood Marrow Transplant."},{"key":"10.1016\/j.jcv.2015.06.097_bib0050","doi-asserted-by":"crossref","first-page":"421","DOI":"10.1046\/j.1365-2141.2003.04788.x","article-title":"Human herpesvirus 6 infection in hematopoietic stem cell transplant patients","volume":"124","author":"Yoshikawa","year":"2004","journal-title":"Br. J. Haematol."},{"key":"10.1016\/j.jcv.2015.06.097_bib0055","doi-asserted-by":"crossref","first-page":"574","DOI":"10.1038\/bmt.2012.180","article-title":"HHV-6 encephalitis in umbilical cord blood transplantation: a systematic review and meta-analysis","volume":"48","author":"Scheurer","year":"2013","journal-title":"Bone Marrow Transplant."},{"key":"10.1016\/j.jcv.2015.06.097_bib0060","doi-asserted-by":"crossref","first-page":"193","DOI":"10.1007\/s13365-011-0019-4","article-title":"Ganciclovir-resistant human herpesvirus-6 encephalitis in a liver transplant patient: a case report","volume":"17","author":"Baldwin","year":"2011","journal-title":"J. Neurovirol."},{"key":"10.1016\/j.jcv.2015.06.097_bib0065","doi-asserted-by":"crossref","first-page":"1494","DOI":"10.1212\/WNL.0b013e31828cf8a2","article-title":"Human herpes 6 virus encephalitis complicating allogeneic hematopoietic stem cell transplantation","volume":"80","author":"Bhanushali","year":"2013","journal-title":"Neurology"},{"key":"10.1016\/j.jcv.2015.06.097_bib0070","doi-asserted-by":"crossref","first-page":"430","DOI":"10.1007\/s12185-013-1278-z","article-title":"Diffuse panbronchiolitis after humanized anti-CCR4 monoclonal antibody therapy for relapsed adult T-cell leukemia\/lymphoma","volume":"97","author":"Kato","year":"2013","journal-title":"Int. J. Hematol."},{"key":"10.1016\/j.jcv.2015.06.097_bib0075","doi-asserted-by":"crossref","first-page":"1139","DOI":"10.1111\/j.1349-7006.2006.00307.x","article-title":"CCR4 as a novel molecular target for immunotherapy of cancer","volume":"97","author":"Ishida","year":"2006","journal-title":"Cancer Sci."},{"key":"10.1016\/j.jcv.2015.06.097_bib0080","doi-asserted-by":"crossref","first-page":"164","DOI":"10.1016\/j.jcv.2011.06.008","article-title":"Deciphering the clinical impact of acute human herpesvirus 6 (HHV-6) infections","volume":"52","author":"Agut","year":"2011","journal-title":"J. Clin. Virol."},{"key":"10.1016\/j.jcv.2015.06.097_bib0085","doi-asserted-by":"crossref","first-page":"286","DOI":"10.1128\/CMR.12.2.286","article-title":"Resistance of human cytomegalovirus to antiviral drugs","volume":"12","author":"Erice","year":"1999","journal-title":"Clin. Microbiol. Rev."},{"key":"10.1016\/j.jcv.2015.06.097_bib0090","doi-asserted-by":"crossref","first-page":"279","DOI":"10.1016\/j.jcv.2013.06.024","article-title":"Analysis of HHV-6 mutations in solid organ transplant recipients at the onset of cytomegalovirus disease and following treatment with intravenous ganciclovir or oral valganciclovir","volume":"58","author":"Bounaadja","year":"2013","journal-title":"J. Clin. Virol."},{"key":"10.1016\/j.jcv.2015.06.097_bib0095","doi-asserted-by":"crossref","first-page":"309","DOI":"10.1086\/338044","article-title":"Effect of antivirals on human herpesvirus 6 replication in hematopoietic stem cell transplant recipients","volume":"34","author":"Zerr","year":"2002","journal-title":"Clin. Infect. Dis."},{"key":"10.1016\/j.jcv.2015.06.097_bib0100","unstructured":"http:\/\/www.sanfordguide.com\/"},{"key":"10.1016\/j.jcv.2015.06.097_bib0105","doi-asserted-by":"crossref","first-page":"53","DOI":"10.1016\/j.pediatrneurol.2010.02.003","article-title":"High-dose ganciclovir in HHV-6 encephalitis of an immunocompetent child","volume":"43","author":"Olli-L\u00e4hdesm\u00e4ki","year":"2010","journal-title":"Pediatr. Neurol."},{"key":"10.1016\/j.jcv.2015.06.097_bib0110","doi-asserted-by":"crossref","first-page":"890","DOI":"10.1086\/427944","article-title":"Evidence of human herpesvirus 6 infection in 4 immunocompetent patients with encephalitis","volume":"40","author":"Isaacson","year":"2005","journal-title":"Clin. Infect. Dis."},{"key":"10.1016\/j.jcv.2015.06.097_bib0115","doi-asserted-by":"crossref","first-page":"634","DOI":"10.1093\/infdis\/162.3.634","article-title":"Susceptibility of human herpesvirus 6 to antivirals in vitro","volume":"162","author":"Burns","year":"1990","journal-title":"J. Infect. Dis."},{"key":"10.1016\/j.jcv.2015.06.097_bib0120","doi-asserted-by":"crossref","first-page":"186","DOI":"10.1002\/rmv.1787","article-title":"Antiviral drug resistance in herpesviruses other than cytomegalovirus","volume":"24","author":"Piret","year":"2014","journal-title":"Rev. Med. Virol."}],"container-title":["Journal of Clinical Virology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1386653215002826?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1386653215002826?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2019,8,27]],"date-time":"2019-08-27T13:54:36Z","timestamp":1566914076000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1386653215002826"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2015,8]]},"references-count":24,"alternative-id":["S1386653215002826"],"URL":"https:\/\/doi.org\/10.1016\/j.jcv.2015.06.097","relation":{},"ISSN":["1386-6532"],"issn-type":[{"value":"1386-6532","type":"print"}],"subject":[],"published":{"date-parts":[[2015,8]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Ganciclovir-resistant HHV-6 encephalitis that progressed rapidly after bone marrow transplantation","name":"articletitle","label":"Article Title"},{"value":"Journal of Clinical Virology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.jcv.2015.06.097","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2015 Elsevier B.V. All rights reserved.","name":"copyright","label":"Copyright"}]}}