{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,20]],"date-time":"2026-10-20T03:52:07Z","timestamp":1792468327157,"version":"4.5.0"},"reference-count":29,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2016,4,1]],"date-time":"2016-04-01T00:00:00Z","timestamp":1459468800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":["journalofclinicalvirology.com","clinicalkey.jp","clinicalkey.com","clinicalkey.es","clinicalkey.com.au","clinicalkey.fr","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Journal of Clinical Virology"],"published-print":{"date-parts":[[2016,4]]},"DOI":"10.1016\/j.jcv.2016.01.013","type":"journal-article","created":{"date-parts":[[2016,1,29]],"date-time":"2016-01-29T09:45:23Z","timestamp":1454060723000},"page":"5-8","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":30,"special_numbering":"C","title":["Human pegivirus detected in a patient with severe encephalitis using a metagenomic pan-virus array"],"prefix":"10.1016","volume":"77","author":[{"given":"Helena","family":"Fridholm","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Line","family":"\u00d8stergaard S\u00f8rensen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Maiken W.","family":"Rosenstierne","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Henrik","family":"Nielsen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Finn","family":"Sellebjerg","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"\u00c5se","family":"Beng\u00e5rd Andersen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anders","family":"Fomsgaard","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.jcv.2016.01.013_bib0005","doi-asserted-by":"crossref","first-page":"e31886","DOI":"10.1371\/journal.pone.0031886","article-title":"Deep sequencing for the detection of virus-like sequences in the brains of patients with multiple sclerosis: detection of GBV-C in human brain","volume":"7","author":"Kriesel","year":"2012","journal-title":"PLoS One"},{"key":"10.1016\/j.jcv.2016.01.013_bib0010","doi-asserted-by":"crossref","first-page":"124","DOI":"10.1016\/j.tim.2012.01.004","article-title":"GB virus C: the good boy virus?","volume":"20","author":"Bhattarai","year":"2012","journal-title":"Trends Microbiol."},{"key":"10.1016\/j.jcv.2016.01.013_bib0015","doi-asserted-by":"crossref","first-page":"277","DOI":"10.1111\/j.1747-0285.2011.01143.x","article-title":"Diagnostic value of anti-GBV-C antibodies in HIV-infected patients","volume":"78","author":"G\u00f3mara","year":"2011","journal-title":"Chem. Biol. Drug Design"},{"key":"10.1016\/j.jcv.2016.01.013_bib0020","doi-asserted-by":"crossref","first-page":"2425","DOI":"10.1128\/JVI.02752-14","article-title":"GB virus C coinfections in West African Ebola patients","volume":"89","author":"Lauck","year":"2015","journal-title":"J. Virol."},{"key":"10.1016\/j.jcv.2016.01.013_bib0025","doi-asserted-by":"crossref","first-page":"1012","DOI":"10.1093\/cid\/cis589","article-title":"Acquisition of GB virus type C and lower mortality in patients with advanced HIV disease","volume":"55","author":"Vahidnia","year":"2012","journal-title":"Clin. Infect. Dis."},{"key":"10.1016\/j.jcv.2016.01.013_bib0030","doi-asserted-by":"crossref","first-page":"e100813","DOI":"10.1371\/journal.pone.0100813","article-title":"The microbial detection array for detection of emerging viruses in clinical samples\u2014a useful panmicrobial diagnostic tool","volume":"9","author":"Rosenstierne","year":"2014","journal-title":"PLoS One"},{"key":"10.1016\/j.jcv.2016.01.013_bib0035","doi-asserted-by":"crossref","first-page":"668","DOI":"10.1186\/1471-2164-11-668","article-title":"A microbial detection array (MDA) for viral and bacterial detection","volume":"11","author":"Gardner","year":"2010","journal-title":"BMC Genomics"},{"key":"10.1016\/j.jcv.2016.01.013_bib0040","doi-asserted-by":"crossref","first-page":"47","DOI":"10.1016\/j.jviromet.2008.03.023","article-title":"Multiplex real-time PCR for the detection and quantification of latent and persistent viral genomes in cellular or plasma blood fractions","volume":"151","author":"Compston","year":"2008","journal-title":"J. Virol. Methods"},{"key":"10.1016\/j.jcv.2016.01.013_bib0045","doi-asserted-by":"crossref","first-page":"378","DOI":"10.1046\/j.1537-2995.1998.38498257377.x","article-title":"Hepatitis C virus and GB virus C\/hepatitis G virus viremia in Swedish blood donors with different alanine aminotransferase levels","volume":"38","author":"Bj\u00f6rkman","year":"1998","journal-title":"Transfusion"},{"key":"10.1016\/j.jcv.2016.01.013_bib0050","doi-asserted-by":"crossref","first-page":"685","DOI":"10.1002\/jmv.22029","article-title":"Evidence for extensive genotypic diversity and recombination of GB virus C (GBV-C) in Germany","volume":"83","author":"Neibecker","year":"2011","journal-title":"J. Med. Virol."},{"key":"10.1016\/j.jcv.2016.01.013_bib0055","doi-asserted-by":"crossref","first-page":"233","DOI":"10.1099\/vir.0.027490-0","article-title":"The GB viruses: a review and proposed classification of GBV-A, GBV-C (HGV), and GBV-D in genus Pegivirus within the family Flaviviridae","volume":"92","author":"Stapleton","year":"2011","journal-title":"J. Gen. Virol."},{"key":"10.1016\/j.jcv.2016.01.013_bib0060","doi-asserted-by":"crossref","first-page":"569","DOI":"10.1046\/j.1537-2995.1997.37697335149.x","article-title":"G-pers creepers, where'd you get those papers? A reassessment of the literature on the hepatitis G virus","volume":"37","author":"Alter","year":"1997","journal-title":"Transfusion"},{"issue":"78","key":"10.1016\/j.jcv.2016.01.013_bib0065","article-title":"GB virus-C\u2014a virus without a disease: we cannot give it chronic fatigue syndrome","volume":"5","author":"Jones","year":"2005","journal-title":"BMC Infect. Dis."},{"key":"10.1016\/j.jcv.2016.01.013_bib0070","doi-asserted-by":"crossref","first-page":"539","DOI":"10.1080\/00365549850161647","article-title":"Lack of GB virus C\/hepatitis G virus sequences in cerebrospinal fluid in patients with central nervous system infections","volume":"30","author":"Radkowski","year":"1998","journal-title":"Scand. J. Infect. Dis."},{"key":"10.1016\/j.jcv.2016.01.013_bib0075","doi-asserted-by":"crossref","first-page":"148","DOI":"10.1046\/j.1423-0410.2001.00098.x","article-title":"A case-control study of transmission routes for GB virus C\/hepatitis G virus in Swedish blood donors lacking markers for hepatitis C virus infection","volume":"81","author":"Bj\u00f6rkman","year":"2001","journal-title":"Vox Sang."},{"key":"10.1016\/j.jcv.2016.01.013_bib0080","doi-asserted-by":"crossref","first-page":"611","DOI":"10.1080\/00365540110026755","article-title":"GB virus C\/hepatitis G virus infection in patients investigated for chronic liver disease and in the general population in southern Sweden","volume":"33","author":"Bj\u00f6rkman","year":"2001","journal-title":"Scand. J. Infect. Dis."},{"key":"10.1016\/j.jcv.2016.01.013_bib0085","doi-asserted-by":"crossref","first-page":"2584","DOI":"10.1128\/JCM.38.7.2584-2590.2000","article-title":"Prevalence of GB virus C (also called hepatitis G virus) markers in Norwegian blood donors","volume":"38","author":"Nordb\u00f8","year":"2000","journal-title":"J. Clin. Microbiol."},{"key":"10.1016\/j.jcv.2016.01.013_bib0090","doi-asserted-by":"crossref","first-page":"167","DOI":"10.1002\/(SICI)1096-9071(199710)53:2<167::AID-JMV10>3.0.CO;2-G","article-title":"Seroprevalence of GB virus C and persistence of RNA and antibody","volume":"53","author":"Gutierrez","year":"1997","journal-title":"J. Med. Virol."},{"key":"10.1016\/j.jcv.2016.01.013_bib0095","first-page":"14","article-title":"A novel T cell evasion mechanism in persistent RNA virus infection","volume":"125","author":"Stapleton","year":"2014","journal-title":"Trans. Am. Clin. Climatol. Assoc."},{"key":"10.1016\/j.jcv.2016.01.013_bib0100","doi-asserted-by":"crossref","first-page":"1626","DOI":"10.1002\/hep.510260635","article-title":"Humoral immune response to the E2 protein of hepatitis G virus is associated with long-term recovery from infection and reveals a high frequency of hepatitis G virus exposure among healthy blood donors","volume":"26","author":"Tacke","year":"1997","journal-title":"Hepatology"},{"key":"10.1016\/j.jcv.2016.01.013_bib0105","doi-asserted-by":"crossref","first-page":"156","DOI":"10.1002\/jmv.10359","article-title":"GB Virus C epidemiology in denmark: different routes of transmission in children and low- and high-risk adults","volume":"70","author":"Christensen","year":"2003","journal-title":"J. Med. Virol."},{"key":"10.1016\/j.jcv.2016.01.013_bib0110","doi-asserted-by":"crossref","first-page":"318","DOI":"10.1016\/S0140-6736(96)06461-6","article-title":"Detection of antibodies to a putative hepatitis G virus envelope protein","volume":"349","author":"Tacke","year":"1997","journal-title":"Lancet"},{"key":"10.1016\/j.jcv.2016.01.013_bib0115","doi-asserted-by":"crossref","first-page":"354","DOI":"10.1002\/(SICI)1096-9071(199712)53:4<354::AID-JMV7>3.0.CO;2-6","article-title":"Antibody to GBV-C second envelope glycoprotein (anti-GBV-C E2): is it a marker for immunity?","volume":"53","author":"Hassoba","year":"1997","journal-title":"J. Med. Virol."},{"key":"10.1016\/j.jcv.2016.01.013_bib0120","doi-asserted-by":"crossref","first-page":"373","DOI":"10.1002\/(SICI)1096-9071(199908)58:4<373::AID-JMV9>3.0.CO;2-1","article-title":"Prevalence of GBV-C\/hepatitis G virus RNA and E2 antibody among subjects infected with human immunodeficiency virus type 1 after parenteral or sexual exposure","volume":"58","author":"Bourlet","year":"1999","journal-title":"J. Med. Virol."},{"key":"10.1016\/j.jcv.2016.01.013_bib0125","doi-asserted-by":"crossref","first-page":"52","DOI":"10.1002\/(SICI)1096-9071(200005)61:1<52::AID-JMV8>3.0.CO;2-L","article-title":"Evidence that the GBV-C\/Hepatitis G virus is primarily a lymphotropic virus","volume":"61","author":"Tucker","year":"2000","journal-title":"J. Med. Virol."},{"key":"10.1016\/j.jcv.2016.01.013_bib0130","doi-asserted-by":"crossref","first-page":"835","DOI":"10.1016\/S1473-3099(10)70222-X","article-title":"Causes of encephalitis and differences in their clinical presentations in England: a multicentre, population-based prospective study","volume":"10","author":"Granerod","year":"2010","journal-title":"Lancet Infect. Dis."},{"key":"10.1016\/j.jcv.2016.01.013_bib0135","doi-asserted-by":"crossref","first-page":"1359","DOI":"10.3201\/eid1509.081540","article-title":"Etiology of encephalitis in Australia 1990\u20132007","volume":"15","author":"Huppatz","year":"2009","journal-title":"Emerg. Infect. Dis."},{"key":"10.1016\/j.jcv.2016.01.013_bib0140","doi-asserted-by":"crossref","first-page":"2408","DOI":"10.1056\/NEJMoa1401268","article-title":"Actionable diagnosis of neuroleptospirosis by next-generation sequencing","volume":"370","author":"Wilson","year":"2014","journal-title":"N. Engl. J. Med."},{"key":"10.1016\/j.jcv.2016.01.013_bib0145","doi-asserted-by":"crossref","first-page":"919","DOI":"10.1093\/cid\/ciu912","article-title":"Diagnosis of neuroinvasive astrovirus infection in an immunocompromised adult with encephalitis by unbiased next-generation sequencing","volume":"60","author":"Naccache","year":"2015","journal-title":"Clin. Infect. Dis."}],"container-title":["Journal of Clinical Virology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1386653216000366?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1386653216000366?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2020,9,14]],"date-time":"2020-09-14T15:51:20Z","timestamp":1600098680000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1386653216000366"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2016,4]]},"references-count":29,"alternative-id":["S1386653216000366"],"URL":"https:\/\/doi.org\/10.1016\/j.jcv.2016.01.013","relation":{},"ISSN":["1386-6532"],"issn-type":[{"value":"1386-6532","type":"print"}],"subject":[],"published":{"date-parts":[[2016,4]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Human pegivirus detected in a patient with severe encephalitis using a metagenomic pan-virus array","name":"articletitle","label":"Article Title"},{"value":"Journal of Clinical Virology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.jcv.2016.01.013","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2016 Elsevier B.V. All rights reserved.","name":"copyright","label":"Copyright"}]}}