{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,15]],"date-time":"2026-07-15T13:36:09Z","timestamp":1784122569268,"version":"3.55.0"},"reference-count":24,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2016,5,1]],"date-time":"2016-05-01T00:00:00Z","timestamp":1462060800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":["journalofclinicalvirology.com","clinicalkey.jp","clinicalkey.com","clinicalkey.es","clinicalkey.com.au","clinicalkey.fr","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Journal of Clinical Virology"],"published-print":{"date-parts":[[2016,5]]},"DOI":"10.1016\/j.jcv.2016.02.026","type":"journal-article","created":{"date-parts":[[2016,3,5]],"date-time":"2016-03-05T05:22:12Z","timestamp":1457155332000},"page":"27-30","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":116,"special_numbering":"C","title":["Direct-acting antiviral treatment in adults infected with hepatitis C virus: Reactivation of hepatitis B virus coinfection as a further challenge"],"prefix":"10.1016","volume":"78","author":[{"given":"Anne","family":"De Monte","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Johan","family":"Courjon","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rodolphe","family":"Anty","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Eric","family":"Cua","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alissa","family":"Naqvi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"V\u00e9ronique","family":"Mondain","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jacqueline","family":"Cottalorda","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Laurence","family":"Ollier","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Val\u00e9rie","family":"Giordanengo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.jcv.2016.02.026_bib0005","doi-asserted-by":"crossref","first-page":"1124","DOI":"10.1016\/S0140-6736(14)62401-6","article-title":"Hepatitis C","volume":"385","author":"Webster","year":"2015","journal-title":"Lancet Lond. Engl."},{"key":"10.1016\/j.jcv.2016.02.026_bib0010","doi-asserted-by":"crossref","first-page":"199","DOI":"10.1016\/j.jhep.2015.03.025","article-title":"EASL recommendations on treatment of hepatitis C","volume":"63","author":"European Association for Study of Liver","year":"2015","journal-title":"J. Hepatol."},{"key":"10.1016\/j.jcv.2016.02.026_bib0015","doi-asserted-by":"crossref","first-page":"932","DOI":"10.1002\/hep.27950","article-title":"Hepatitis C guidance: AASLD-IDSA recommendations for testing, managing, and treating adults infected with hepatitis C virus","volume":"62","author":"AASLD\/IDSA HCV Guidance Panel","year":"2015","journal-title":"Hepatology"},{"key":"10.1016\/j.jcv.2016.02.026_bib0020","doi-asserted-by":"crossref","DOI":"10.1093\/cid\/civ474","article-title":"Hepatitis B virus reactivation during successful treatment of hepatitis C virus with sofosbuvir and simeprevir","author":"Collins","year":"2015","journal-title":"Clin. Infect. Dis."},{"key":"10.1016\/j.jcv.2016.02.026_bib0025","doi-asserted-by":"crossref","first-page":"164","DOI":"10.1186\/s13256-015-0630-8","article-title":"Fulminant hepatitis B reactivation leading to liver transplantation in a patient with chronic hepatitis C treated with simeprevir and sofosbuvir: a case report","volume":"9","author":"Ende","year":"2015","journal-title":"J. Med. Case Reports"},{"key":"10.1016\/j.jcv.2016.02.026_bib0030","article-title":"Reactivation of hepatitis B virus during interferon-free therapy with daclatasvir and asunaprevir in patient with HBV\/HCV co-infection","author":"Takayama","year":"2015","journal-title":"Hepatol. Res."},{"key":"10.1016\/j.jcv.2016.02.026_bib0035","doi-asserted-by":"crossref","first-page":"S156","DOI":"10.1002\/hep.22945","article-title":"Reactivation of hepatitis B","volume":"49","author":"Hoofnagle","year":"2009","journal-title":"Hepatology"},{"key":"10.1016\/j.jcv.2016.02.026_bib0040","doi-asserted-by":"crossref","first-page":"164","DOI":"10.1111\/liv.12081","article-title":"Management of acute hepatitis B and reactivation of hepatitis B","volume":"33","author":"Jindal","year":"2013","journal-title":"Liver Int."},{"key":"10.1016\/j.jcv.2016.02.026_bib0045","first-page":"221","article-title":"The spectrum of HBV\/HCV coinfection: epidemiology, clinical characteristics, viralinteractions and management","volume":"28","author":"Konstantinou","year":"2015","journal-title":"Ann. Gastroenterol. Q. Publ. Hell. Soc. Gastroenterol."},{"key":"10.1016\/j.jcv.2016.02.026_bib0050","doi-asserted-by":"crossref","first-page":"636","DOI":"10.1046\/j.1440-1746.2001.02494.x","article-title":"Influence of hepatitis C virus on the profiles of patients with chronic hepatitis B virus infection","volume":"16","author":"Dai","year":"2001","journal-title":"J. Gastroenterol. Hepatol."},{"key":"10.1016\/j.jcv.2016.02.026_bib0055","doi-asserted-by":"crossref","first-page":"64","DOI":"10.1002\/hep.1840140111","article-title":"The significance of antibody to hepatitis C virus in patients with chronic hepatitis B","volume":"14","author":"Fong","year":"1991","journal-title":"Hepatology"},{"key":"10.1016\/j.jcv.2016.02.026_bib0060","doi-asserted-by":"crossref","first-page":"317","DOI":"10.1016\/j.jcv.2005.10.006","article-title":"Hepatitis C virus superinfection in hepatitis B virus chronic carriers: a reciprocal viral interaction and a variable clinical course","volume":"35","author":"Sagnelli","year":"2006","journal-title":"J. Clin. Virol."},{"key":"10.1016\/j.jcv.2016.02.026_bib0065","doi-asserted-by":"crossref","first-page":"722","DOI":"10.1111\/j.1478-3231.2007.01477.x","article-title":"Profound suppression of chronic hepatitis C following superinfection with hepatitis B virus","volume":"27","author":"Coffin","year":"2007","journal-title":"Liver Int."},{"key":"10.1016\/j.jcv.2016.02.026_bib0070","doi-asserted-by":"crossref","first-page":"1487","DOI":"10.3109\/00365520903329585","article-title":"HEP-NET B\/C Coinfection Study Group: late hepatitis B virus relapse in patients co-infected with hepatitis B virus and hepatitis C virus after antiviral treatment with pegylated interferon-a2b and ribavirin","volume":"44","author":"Potthoff","year":"2009","journal-title":"Scand. J. Gastroenterol."},{"key":"10.1016\/j.jcv.2016.02.026_bib0075","doi-asserted-by":"crossref","first-page":"591","DOI":"10.1074\/jbc.M204241200","article-title":"Mechanisms for inhibition of hepatitis B virus gene expression and replication by hepatitis C virus core protein","volume":"278","author":"Chen","year":"2003","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.jcv.2016.02.026_bib0080","doi-asserted-by":"crossref","first-page":"855","DOI":"10.1016\/S0168-8278(02)00296-9","article-title":"Suppression of hepatitis B virus enhancer 1 and 2 by hepatitis C virus core protein","volume":"37","author":"Sch\u00fcttler","year":"2002","journal-title":"J. Hepatol."},{"key":"10.1016\/j.jcv.2016.02.026_bib0085","doi-asserted-by":"crossref","first-page":"719","DOI":"10.1002\/hep.510250338","article-title":"Hepatitis C virus core and E2 protein expression in transgenic mice","volume":"25","author":"Pasquinelli","year":"1997","journal-title":"Hepatology"},{"key":"10.1016\/j.jcv.2016.02.026_bib0090","doi-asserted-by":"crossref","first-page":"70","DOI":"10.1016\/j.bbrc.2007.05.052","article-title":"NS5A protein of HCV enhances HBV replication and resistance to interferon response","volume":"359","author":"Pan","year":"2007","journal-title":"Biochem. Biophys. Res. Commun."},{"key":"10.1016\/j.jcv.2016.02.026_bib0095","doi-asserted-by":"crossref","first-page":"446","DOI":"10.1016\/j.jhep.2009.04.025","article-title":"Hepatitis B virus and hepatitis C virus interaction in Huh-7 cells","volume":"51","author":"Eyre","year":"2009","journal-title":"J. Hepatol."},{"key":"10.1016\/j.jcv.2016.02.026_bib0100","doi-asserted-by":"crossref","first-page":"46","DOI":"10.1002\/hep.22951","article-title":"Hepatitis B and C virus coinfection: a novel model system reveals the absence of direct viral interference","volume":"50","author":"Bellecave","year":"2009","journal-title":"Hepatology"},{"key":"10.1016\/j.jcv.2016.02.026_bib0105","doi-asserted-by":"crossref","first-page":"710.e1","DOI":"10.1016\/j.cmi.2015.03.003","article-title":"Dominance of hepatitis C virus (HCV) is associated with lower quantitative hepatitis B surface antigen and higher serum interferon-\u03b3-induced protein 10 levels in HBV\/HCV-coinfected patients","volume":"21","author":"Wiegand","year":"2015","journal-title":"Clin. Microbiol. Infect."},{"key":"10.1016\/j.jcv.2016.02.026_bib0110","doi-asserted-by":"crossref","first-page":"10072","DOI":"10.1128\/JVI.00541-07","article-title":"Regulation of hepatitis B virus replication by the phosphatidylinositol 3-kinase-akt signal transduction pathway","volume":"81","author":"Guo","year":"2007","journal-title":"J. Virol."},{"key":"10.1016\/j.jcv.2016.02.026_bib0115","doi-asserted-by":"crossref","first-page":"260","DOI":"10.1006\/viro.2002.1701","article-title":"Hepatitis C virus NS2 protein inhibits gene expression from different cellular and viral promoters in hepatic and nonhepatic cell lines","volume":"305","author":"Dumoulin","year":"2003","journal-title":"Virology"},{"key":"10.1016\/j.jcv.2016.02.026_bib0120","doi-asserted-by":"crossref","first-page":"498","DOI":"10.4254\/wjh.v7.i3.498","article-title":"MiR-122 in hepatitis B virus and hepatitis C virus dual infection","volume":"7","author":"Song","year":"2015","journal-title":"World J. Hepatol."}],"container-title":["Journal of Clinical Virology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1386653216300178?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1386653216300178?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2018,9,14]],"date-time":"2018-09-14T15:55:03Z","timestamp":1536940503000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1386653216300178"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2016,5]]},"references-count":24,"alternative-id":["S1386653216300178"],"URL":"https:\/\/doi.org\/10.1016\/j.jcv.2016.02.026","relation":{},"ISSN":["1386-6532"],"issn-type":[{"value":"1386-6532","type":"print"}],"subject":[],"published":{"date-parts":[[2016,5]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Direct-acting antiviral treatment in adults infected with hepatitis C virus: Reactivation of hepatitis B virus coinfection as a further challenge","name":"articletitle","label":"Article Title"},{"value":"Journal of Clinical Virology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.jcv.2016.02.026","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2016 Elsevier B.V. All rights reserved.","name":"copyright","label":"Copyright"}]}}