{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,15]],"date-time":"2026-06-15T04:27:26Z","timestamp":1781497646810,"version":"3.54.1"},"reference-count":21,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2019,12,1]],"date-time":"2019-12-01T00:00:00Z","timestamp":1575158400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2019,12,1]],"date-time":"2019-12-01T00:00:00Z","timestamp":1575158400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2019,11,4]],"date-time":"2019-11-04T00:00:00Z","timestamp":1572825600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"funder":[{"DOI":"10.13039\/100015160","name":"Hologic, Inc.","doi-asserted-by":"crossref","id":[{"id":"10.13039\/100015160","id-type":"DOI","asserted-by":"crossref"}]},{"DOI":"10.13039\/100016545","name":"Roche Diagnostics","doi-asserted-by":"crossref","id":[{"id":"10.13039\/100016545","id-type":"DOI","asserted-by":"crossref"}]},{"DOI":"10.13039\/100015124","name":"Abbott Molecular","doi-asserted-by":"crossref","id":[{"id":"10.13039\/100015124","id-type":"DOI","asserted-by":"crossref"}]},{"DOI":"10.13039\/100005442","name":"BD","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100005442","id-type":"DOI","asserted-by":"publisher"}]},{"name":"BioMerieux"},{"DOI":"10.13039\/100017037","name":"Cepheid","doi-asserted-by":"crossref","id":[{"id":"10.13039\/100017037","id-type":"DOI","asserted-by":"crossref"}]},{"DOI":"10.13039\/100015160","name":"Hologic","doi-asserted-by":"crossref","id":[{"id":"10.13039\/100015160","id-type":"DOI","asserted-by":"crossref"}]},{"DOI":"10.13039\/100016545","name":"Roche Diagnostics","doi-asserted-by":"crossref","id":[{"id":"10.13039\/100016545","id-type":"DOI","asserted-by":"crossref"}]}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Journal of Clinical Virology"],"published-print":{"date-parts":[[2019,12]]},"DOI":"10.1016\/j.jcv.2019.104204","type":"journal-article","created":{"date-parts":[[2019,11,9]],"date-time":"2019-11-09T17:58:55Z","timestamp":1573322335000},"page":"104204","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":21,"special_numbering":"C","title":["Panther Fusion\u00ae Respiratory Virus Assays for the detection of influenza and other respiratory viruses"],"prefix":"10.1016","volume":"121","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-0160-6034","authenticated-orcid":false,"given":"Kathleen A.","family":"Stellrecht","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jesse L.","family":"Cimino","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lisa I.","family":"Wilson","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Vincente P.","family":"Maceira","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shafiq A.","family":"Butt","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.jcv.2019.104204_bib0005","doi-asserted-by":"crossref","DOI":"10.1128\/JCM.00711-18","article-title":"Rapid antigen tests for influenza: rationale and significance of the FDA reclassification","volume":"56","author":"Green","year":"2018","journal-title":"J. Clin. Microbiol."},{"key":"10.1016\/j.jcv.2019.104204_bib0010","doi-asserted-by":"crossref","first-page":"344","DOI":"10.1128\/CMR.05016-11","article-title":"Update on influenza diagnostics: lessons from the novel H1N1 influenza A pandemic","volume":"25","author":"Kumar","year":"2012","journal-title":"Clin. Microbiol. Rev."},{"key":"10.1016\/j.jcv.2019.104204_bib0015","doi-asserted-by":"crossref","DOI":"10.7326\/M17-0848","article-title":"Diagnostic accuracy of novel and traditional rapid tests for influenza infection compared with reverse transcriptase polymerase chain reaction: a systematic review and meta-analysis","author":"Merckx","year":"2017","journal-title":"Ann. Intern. Med."},{"key":"10.1016\/j.jcv.2019.104204_bib0020","article-title":"Clinical practice guidelines by the infectious diseases society of america: 2018 update on diagnosis, treatment, Chemoprophylaxis, and institutional outbreak management of seasonal influenza","author":"Uyeki","year":"2018","journal-title":"Clin. Infect. Dis."},{"key":"10.1016\/j.jcv.2019.104204_bib0025","doi-asserted-by":"crossref","first-page":"2417","DOI":"10.1007\/s00705-016-2930-8","article-title":"Influenza A virus drift variants reduced the detection sensitivity of a commercial multiplex nucleic acid amplification assay in the season 2014\/15","volume":"161","author":"Huzly","year":"2016","journal-title":"Arch. Virol."},{"key":"10.1016\/j.jcv.2019.104204_bib0030","doi-asserted-by":"crossref","first-page":"42","DOI":"10.1016\/j.diagmicrobio.2016.02.004","article-title":"Severe sensitivity loss in an influenza A molecular assay due to antigenic drift variants during the 2014\/15 influenza season","volume":"85","author":"Overmeire","year":"2016","journal-title":"Diagn. Microbiol. Infect. Dis."},{"key":"10.1016\/j.jcv.2019.104204_bib0035","doi-asserted-by":"crossref","first-page":"25","DOI":"10.1016\/j.jcv.2017.05.016","article-title":"Effect of genomic drift of influenza PCR tests","volume":"93","author":"Stellrecht","year":"2017","journal-title":"J. Clin. Virol."},{"key":"10.1016\/j.jcv.2019.104204_bib0040","doi-asserted-by":"crossref","first-page":"239","DOI":"10.1016\/j.diagmicrobio.2018.02.007","article-title":"Incidence of matrix genes mutations affecting PCR tests among influenza H3N2 clades circulating during the 2014\/15 season","volume":"91","author":"Stellrecht","year":"2018","journal-title":"Diagn. Microbiol. Infect. Dis."},{"key":"10.1016\/j.jcv.2019.104204_bib0045","doi-asserted-by":"crossref","first-page":"11","DOI":"10.1016\/j.jcv.2018.08.002","article-title":"History of matrix genes mutations within PCR target regions among circulating influenza H3N2 clades over ten-plus-years","volume":"107","author":"Stellrecht","year":"2018","journal-title":"J. Clin. Virol."},{"key":"10.1016\/j.jcv.2019.104204_bib0050","first-page":"56","article-title":"The drift in molecular testing for influenza: mutations affecting assay performance","author":"Stellrecht","year":"2018","journal-title":"J. Clin. Microbiol."},{"key":"10.1016\/j.jcv.2019.104204_bib0055","doi-asserted-by":"crossref","first-page":"2111","DOI":"10.1007\/s10096-012-1602-1","article-title":"Methods and recommendations for evaluating and reporting a new diagnostic test","volume":"31","author":"Hess","year":"2012","journal-title":"Eur. J. Clin. Microbiol. Infect. Dis."},{"key":"10.1016\/j.jcv.2019.104204_bib0060","series-title":"Diagnostic Molecular Pathology","first-page":"123","article-title":"Molecular testing for respiratory viruses","author":"Stellrecht","year":"2017"},{"issue":"48","key":"10.1016\/j.jcv.2019.104204_bib0065","doi-asserted-by":"crossref","first-page":"3870","DOI":"10.1128\/JCM.02464-09","article-title":"Evaluation of three influenza A and B real-time reverse transcription-PCR assays and a new 2009 H1N1 assay for detection of influenza viruses","author":"Selvaraju","year":"2010","journal-title":"J. Clin. Microbiol."},{"key":"10.1016\/j.jcv.2019.104204_bib0070","doi-asserted-by":"crossref","first-page":"4083","DOI":"10.1128\/JCM.05010-11","article-title":"Comparison of the FilmArray Respiratory Panel and Prodesse real-time PCR assays for detection of respiratory pathogens","volume":"49","author":"Loeffelholz","year":"2011","journal-title":"J. Clin. Microbiol."},{"issue":"50","key":"10.1016\/j.jcv.2019.104204_bib0075","doi-asserted-by":"crossref","first-page":"1704","DOI":"10.1128\/JCM.06520-11","article-title":"Evaluation of the Cepheid Xpert Flu Assay for rapid identification and differentiation of influenza A, influenza A 2009 H1N1, and influenza B viruses","author":"Novak-Weekley","year":"2012","journal-title":"J. Clin. Microbiol."},{"key":"10.1016\/j.jcv.2019.104204_bib0080","doi-asserted-by":"crossref","first-page":"40","DOI":"10.1128\/JCM.01978-12","article-title":"Clinical accuracy of a PLEX-ID flu device for simultaneous detection and identification of influenza viruses A and B","volume":"51","author":"Tang","year":"2013","journal-title":"J. Clin. Microbiol."},{"key":"10.1016\/j.jcv.2019.104204_bib0085","doi-asserted-by":"crossref","first-page":"232","DOI":"10.1016\/j.diagmicrobio.2013.11.016","article-title":"Influenza and respiratory syncytial virus detection in clinical specimens without nucleic acid extraction using FOCUS direct disc assay is substantially equivalent to the traditional methods and the FOCUS nucleic acid extraction-dependent RT-PCR assay","volume":"78","author":"Selvaraju","year":"2014","journal-title":"Diagn. Microbiol. Infect. Dis."},{"key":"10.1016\/j.jcv.2019.104204_bib0090","doi-asserted-by":"crossref","first-page":"406","DOI":"10.1016\/j.jcv.2014.08.010","article-title":"Comparison of three commercial RT-PCR systems for the detection of respiratory viruses","volume":"61","author":"Butt","year":"2014","journal-title":"J. Clin. Virol."},{"key":"10.1016\/j.jcv.2019.104204_bib0095","first-page":"56","article-title":"Comparison of six sample-to-Answer influenza A\/B and respiratory syncytial virus nucleic acid amplification assays using respiratory specimens from children","author":"Banerjee","year":"2018","journal-title":"J. Clin. Microbiol."},{"key":"10.1016\/j.jcv.2019.104204_bib0100","first-page":"56","article-title":"Evaluation of performance characteristics of panther fusion assays for detection of respiratory viruses from nasopharyngeal and lower respiratory tract specimens","author":"Sam","year":"2018","journal-title":"J. Clin. Microbiol."},{"key":"10.1016\/j.jcv.2019.104204_bib0105","series-title":"Statistical Guidance on Reporting Results From Studies Evaluating Diagnostic Tests","author":"FDA","year":"2007"}],"container-title":["Journal of Clinical Virology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1386653219302343?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1386653219302343?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,25]],"date-time":"2025-10-25T03:11:19Z","timestamp":1761361879000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1386653219302343"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019,12]]},"references-count":21,"alternative-id":["S1386653219302343"],"URL":"https:\/\/doi.org\/10.1016\/j.jcv.2019.104204","relation":{},"ISSN":["1386-6532"],"issn-type":[{"value":"1386-6532","type":"print"}],"subject":[],"published":{"date-parts":[[2019,12]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Panther Fusion\u00ae Respiratory Virus Assays for the detection of influenza and other respiratory viruses","name":"articletitle","label":"Article Title"},{"value":"Journal of Clinical Virology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.jcv.2019.104204","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2019 The Author(s). Published by Elsevier B.V.","name":"copyright","label":"Copyright"}],"article-number":"104204"}}