{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,12]],"date-time":"2026-04-12T07:17:06Z","timestamp":1775978226736,"version":"3.50.1"},"reference-count":45,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2021,10,1]],"date-time":"2021-10-01T00:00:00Z","timestamp":1633046400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2021,10,1]],"date-time":"2021-10-01T00:00:00Z","timestamp":1633046400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2021,8,16]],"date-time":"2021-08-16T00:00:00Z","timestamp":1629072000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100012023","name":"Sanquin Blood Supply Foundation","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100012023","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Journal of Clinical Virology"],"published-print":{"date-parts":[[2021,10]]},"DOI":"10.1016\/j.jcv.2021.104944","type":"journal-article","created":{"date-parts":[[2021,8,16]],"date-time":"2021-08-16T11:36:33Z","timestamp":1629113793000},"page":"104944","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":11,"special_numbering":"C","title":["JC and Human polyomavirus 9 after kidney transplantation: An exploratory serological cohort study"],"prefix":"10.1016","volume":"143","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-2758-5603","authenticated-orcid":false,"given":"Sergio","family":"Kamminga","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0438-5350","authenticated-orcid":false,"given":"Aline L.","family":"van Rijn","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9117-6658","authenticated-orcid":false,"given":"Caroline S.","family":"de Brouwer","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9682-6234","authenticated-orcid":false,"given":"Joris I.","family":"Rotmans","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0773-7315","authenticated-orcid":false,"given":"Hans L.","family":"Zaaijer","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5993-9846","authenticated-orcid":false,"given":"Mariet C.W.","family":"Feltkamp","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"issue":"10","key":"10.1016\/j.jcv.2021.104944_bib0001","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0206273","article-title":"Seroprevalence of fourteen human polyomaviruses determined in blood donors","volume":"13","author":"Kamminga","year":"2018","journal-title":"PLoS ONE"},{"issue":"4","key":"10.1016\/j.jcv.2021.104944_bib0002","doi-asserted-by":"crossref","first-page":"856","DOI":"10.1111\/ajt.14208","article-title":"Infection in Organ Transplantation","volume":"17","author":"Fishman","year":"2017","journal-title":"Am. J. Transplant."},{"key":"10.1016\/j.jcv.2021.104944_bib0003","unstructured":"Polyomaviridae - Polyomaviridae - dsDNA Viruses [Internet]. International Committee on Taxonomy of Viruses (ICTV). [cited 2020 Sep 7]. Available from: https:\/\/talk.ictvonline.org\/ictv-reports\/ictv_online_report\/dsdna-viruses\/w\/polyomaviridae."},{"issue":"8","key":"10.1016\/j.jcv.2021.104944_bib0004","doi-asserted-by":"crossref","first-page":"685","DOI":"10.1111\/apm.12128","article-title":"The human JC polyomavirus (JCPyV): virological background and clinical implications","volume":"121","author":"Hirsch","year":"2013","journal-title":"APMIS"},{"key":"10.1016\/j.jcv.2021.104944_bib0005","doi-asserted-by":"crossref","DOI":"10.1155\/2013\/926391","article-title":"A Review on JC Virus Infection in Kidney Transplant Recipients","author":"Delbue","year":"2013","journal-title":"Clin. Dev. Immunol."},{"issue":"3","key":"10.1016\/j.jcv.2021.104944_bib0006","doi-asserted-by":"crossref","first-page":"323","DOI":"10.1097\/01.tp.0000269706.59977.a5","article-title":"Polyomavirus BK versus JC replication and nephropathy in renal transplant recipients: a prospective evaluation","volume":"84","author":"Drachenberg","year":"2007","journal-title":"Transplantation"},{"issue":"5866","key":"10.1016\/j.jcv.2021.104944_bib0007","doi-asserted-by":"crossref","first-page":"1096","DOI":"10.1126\/science.1152586","article-title":"Clonal Integration of a Polyomavirus in Human Merkel Cell Carcinoma","volume":"319","author":"Feng","year":"2008","journal-title":"Science"},{"issue":"6","key":"10.1016\/j.jcv.2021.104944_bib0008","doi-asserted-by":"crossref","first-page":"1314","DOI":"10.1111\/bjd.18218","article-title":"Merkel cell carcinoma in kidney transplant recipients in Ireland 1964\u20132018","volume":"181","author":"Keeling","year":"2019","journal-title":"Br. J. Dermatol."},{"issue":"4","key":"10.1016\/j.jcv.2021.104944_bib0009","first-page":"290","article-title":"Merkel cell carcinoma: a review","volume":"97","author":"Oram","year":"2016","journal-title":"Cutis"},{"issue":"1","key":"10.1016\/j.jcv.2021.104944_bib0010","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1038\/nrdp.2017.77","article-title":"Merkel cell carcinoma","volume":"3","author":"Becker","year":"2017","journal-title":"Nat. Rev. Dis. Primers"},{"key":"10.1016\/j.jcv.2021.104944_bib0011","doi-asserted-by":"crossref","DOI":"10.1111\/trf.15557","article-title":"Prevalence of DNA of fourteen human polyomaviruses determined in blood donors","author":"Kamminga","year":"2019","journal-title":"Transfusion"},{"key":"10.1016\/j.jcv.2021.104944_bib0012","doi-asserted-by":"crossref","DOI":"10.1016\/j.meegid.2020.104563","article-title":"Molecular evolution pattern of Merkel cell polyomavirus identified by viral metagenomics in plasma of high-risk blood donors from the Brazilian Amazon","volume":"85","author":"dos Santos Bezerra","year":"2020","journal-title":"Infection, Genetics and Evol."},{"issue":"8","key":"10.1016\/j.jcv.2021.104944_bib0013","doi-asserted-by":"crossref","first-page":"770","DOI":"10.1111\/apm.12092","article-title":"The trichodysplasia spinulosa-associated polyomavirus: virological background and clinical implications","volume":"121","author":"Kazem","year":"2013","journal-title":"APMIS"},{"key":"10.1016\/j.jcv.2021.104944_bib0014","doi-asserted-by":"crossref","first-page":"jiw403","DOI":"10.1093\/infdis\/jiw403","article-title":"Primary Polyomavirus Infection, Not Reactivation, as the Cause of Trichodysplasia Spinulosa in Immunocompromised Patients","author":"van der Meijden","year":"2016","journal-title":"J. Infect. Dis."},{"issue":"9","key":"10.1016\/j.jcv.2021.104944_bib0015","doi-asserted-by":"crossref","first-page":"4586","DOI":"10.1128\/JVI.02602-10","article-title":"A Novel Human Polyomavirus Closely Related to the African Green Monkey-Derived Lymphotropic Polyomavirus","volume":"85","author":"Scuda","year":"2011","journal-title":"J. Virol."},{"issue":"6","key":"10.1016\/j.jcv.2021.104944_bib0016","doi-asserted-by":"crossref","first-page":"991","DOI":"10.3201\/eid2006.140055","article-title":"Human polyomavirus 9 infection in kidney transplant patients","volume":"20","author":"van der Meijden","year":"2014","journal-title":"Emerging Infect Dis"},{"key":"10.1016\/j.jcv.2021.104944_bib0017","article-title":"Impact of HPyV9 and TSPyV coinfection on the development of BK polyomavirus viremia and associated nephropathy after kidney transplantation","author":"Rijn","year":"2019","journal-title":"J. Med. Virol."},{"issue":"5","key":"10.1016\/j.jcv.2021.104944_bib0018","doi-asserted-by":"crossref","first-page":"932","DOI":"10.1016\/j.jaad.2016.11.035","article-title":"Human polyomavirus 6 and 7 are associated with pruritic and dyskeratotic dermatoses","volume":"76","author":"Nguyen","year":"2017","journal-title":"J. Am. Acad. Dermatol."},{"issue":"10","key":"10.1016\/j.jcv.2021.104944_bib0019","doi-asserted-by":"crossref","first-page":"1560","DOI":"10.1093\/infdis\/jiu524","article-title":"Human Polyomavirus 7\u2013Associated Pruritic Rash and Viremia in Transplant Recipients","volume":"211","author":"Ho","year":"2015","journal-title":"J. Infect. Dis."},{"issue":"5","key":"10.1016\/j.jcv.2021.104944_bib0020","doi-asserted-by":"crossref","first-page":"e64","DOI":"10.1371\/journal.ppat.0030064","article-title":"Identification of a Novel Polyomavirus from Patients with Acute Respiratory Tract Infections","volume":"3","author":"Gaynor","year":"2007","journal-title":"PLoS Pathog."},{"issue":"8","key":"10.1016\/j.jcv.2021.104944_bib0021","doi-asserted-by":"crossref","first-page":"4130","DOI":"10.1128\/JVI.00028-07","article-title":"Identification of a Third Human Polyomavirus","volume":"81","author":"Allander","year":"2007","journal-title":"J. Virol."},{"key":"10.1016\/j.jcv.2021.104944_bib0022","doi-asserted-by":"crossref","first-page":"112","DOI":"10.1016\/j.jcv.2016.07.013","article-title":"WU and KI polyomavirus infections in Filipino children with lower respiratory tract disease","volume":"82","author":"Rao","year":"2016","journal-title":"J. Clin. Virol."},{"issue":"10","key":"10.1016\/j.jcv.2021.104944_bib0023","doi-asserted-by":"crossref","first-page":"1595","DOI":"10.1093\/infdis\/jiu250","article-title":"Identification of a novel polyomavirus in a pancreatic transplant recipient with retinal blindness and vasculitic myopathy","volume":"210","author":"Mishra","year":"2014","journal-title":"J. Infect. Dis."},{"key":"10.1016\/j.jcv.2021.104944_bib0024","doi-asserted-by":"crossref","DOI":"10.1099\/jgv.0.001156","article-title":"Prevalence and risk factors of human polyomavirus infections in non-malignant tonsils and gargles: the SPLIT study","author":"Kourieh","year":"2018","journal-title":"J. General Virol. [Internet]"},{"issue":"11","key":"10.1016\/j.jcv.2021.104944_bib0025","article-title":"Different Serologic Behavior of MCPyV, TSPyV, HPyV6, HPyV7 and HPyV9 Polyomaviruses Found on the Skin","volume":"8","author":"van der Meijden","year":"2013","journal-title":"PLoS One [Internet]"},{"issue":"1","key":"10.1016\/j.jcv.2021.104944_bib0026","doi-asserted-by":"crossref","first-page":"161","DOI":"10.1111\/ajt.13880","article-title":"Pretransplantation Donor-Recipient Pair Seroreactivity Against BK Polyomavirus Predicts Viremia and Nephropathy After Kidney Transplantation","volume":"17","author":"Wunderink","year":"2017","journal-title":"Am. J. Transplant."},{"issue":"2","key":"10.1016\/j.jcv.2021.104944_bib0027","doi-asserted-by":"crossref","first-page":"120","DOI":"10.1016\/j.jcv.2013.11.009","article-title":"Donor origin of BKV replication after kidney transplantation","volume":"59","author":"Schmitt","year":"2014","journal-title":"J. Clin. Virol."},{"issue":"6","key":"10.1016\/j.jcv.2021.104944_bib0028","doi-asserted-by":"crossref","first-page":"987","DOI":"10.1093\/cid\/ciy1018","article-title":"Metagenomic Virome Sequencing in Living Donor and Recipient Kidney Transplant Pairs Revealed JC Polyomavirus Transmission","volume":"69","author":"Schreiber","year":"2019","journal-title":"Clin. Infect. Dis."},{"issue":"8","key":"10.1016\/j.jcv.2021.104944_bib0029","doi-asserted-by":"crossref","first-page":"e13586","DOI":"10.1111\/petr.13586","article-title":"JC polyomavirus-specific antibody responses in pediatric kidney transplant recipients","volume":"23","author":"Ylinen","year":"2019","journal-title":"Pediatr. Transplant"},{"issue":"12","key":"10.1016\/j.jcv.2021.104944_bib0030","doi-asserted-by":"crossref","first-page":"3761","DOI":"10.1002\/art.24966","article-title":"Progressive multifocal leukoencephalopathy: a national estimate of frequency in systemic lupus erythematosus and other rheumatic diseases","volume":"60","author":"Molloy","year":"2009","journal-title":"Arthritis & Rheumatism"},{"issue":"4","key":"10.1016\/j.jcv.2021.104944_bib0031","doi-asserted-by":"crossref","DOI":"10.1128\/JCM.01566-17","article-title":"Development and Evaluation of a Broad Bead-Based Multiplex Immunoassay To Measure IgG Seroreactivity against Human Polyomaviruses","volume":"56","author":"Kamminga","year":"2018","journal-title":"J. Clin. Microbiol."},{"key":"10.1016\/j.jcv.2021.104944_bib0032","series-title":"RStudio: Integrated Development Environment for R [Internet]","year":"2015"},{"key":"10.1016\/j.jcv.2021.104944_bib0033","unstructured":"R. Core Team. R: a Language and Environment for Statistical Computing [Internet]. R Foundation for Statistical Computing; 2019. Available from: https:\/\/www.R-project.org\/."},{"issue":"43","key":"10.1016\/j.jcv.2021.104944_bib0034","doi-asserted-by":"crossref","first-page":"1686","DOI":"10.21105\/joss.01686","article-title":"Welcome to the Tidyverse","volume":"4","author":"Wickham","year":"2019","journal-title":"J. Open Source Software"},{"issue":"1","key":"10.1016\/j.jcv.2021.104944_bib0035","doi-asserted-by":"crossref","first-page":"1","DOI":"10.18637\/jss.v067.i01","article-title":"Fitting Linear Mixed-Effects Models Using lme4","volume":"67","author":"Bates","year":"2015","journal-title":"J. Stat. Softw."},{"key":"10.1016\/j.jcv.2021.104944_bib0036","series-title":"Lattice: Multivariate Data Visualization with R [Internet]","author":"Sarkar","year":"2008"},{"issue":"7","key":"10.1016\/j.jcv.2021.104944_bib0037","doi-asserted-by":"crossref","DOI":"10.1093\/nar\/gkv007","article-title":"limma powers differential expression analyses for RNA-sequencing and microarray studies","volume":"43","author":"Ritchie","year":"2015","journal-title":"Nucleic Acids Res."},{"key":"10.1016\/j.jcv.2021.104944_bib0038","article-title":"ggplot2: elegant Graphics for Data Analysis [Internet]. 2nd ed. Springer International Publishing","author":"Wickham","year":"2016","journal-title":"[cited 2020 Apr 7]. (Use R!)"},{"issue":"2","key":"10.1016\/j.jcv.2021.104944_bib0039","doi-asserted-by":"crossref","first-page":"285","DOI":"10.1016\/j.jid.2018.09.013","article-title":"The Biology and Clinical Features of Cutaneous Polyomaviruses","volume":"139","author":"Nguyen","year":"2019","journal-title":"J. Invest. Dermatol."},{"issue":"3","key":"10.1016\/j.jcv.2021.104944_bib0040","article-title":"The blood DNA virome in 8,000 humans","volume":"13","author":"Moustafa","year":"2017","journal-title":"PLoS Pathog. [Internet]"},{"issue":"3","key":"10.1016\/j.jcv.2021.104944_bib0041","doi-asserted-by":"crossref","first-page":"225","DOI":"10.1016\/j.jcv.2011.11.007","article-title":"Trichodysplasia spinulosa is characterized by active polyomavirus infection","volume":"53","author":"Kazem","year":"2012","journal-title":"J. Clin. Virol."},{"issue":"1","key":"10.1016\/j.jcv.2021.104944_bib0042","doi-asserted-by":"crossref","first-page":"161","DOI":"10.1111\/ajt.13880","article-title":"Pretransplantation Donor-Recipient Pair Seroreactivity Against BK Polyomavirus Predicts Viremia and Nephropathy After Kidney Transplantation","volume":"17","author":"Wunderink","year":"2017","journal-title":"Am. J. Transplant."},{"issue":"1","key":"10.1016\/j.jcv.2021.104944_bib0043","doi-asserted-by":"crossref","first-page":"61","DOI":"10.1093\/aje\/kwv155","article-title":"Seroepidemiology of Human Polyomaviruses in a US Population","volume":"183","author":"Gossai","year":"2016","journal-title":"Am. J. Epidemiol."},{"issue":"5","key":"10.1016\/j.jcv.2021.104944_bib0044","doi-asserted-by":"crossref","first-page":"825","DOI":"10.1681\/ASN.2010080877","article-title":"Inhibitory Interactions between BK and JC Virus among Kidney Transplant Recipients","volume":"22","author":"Cheng","year":"2011","journal-title":"JASN"},{"issue":"9","key":"10.1016\/j.jcv.2021.104944_bib0045","doi-asserted-by":"crossref","first-page":"2213","DOI":"10.1111\/j.1600-6143.2005.01000.x","article-title":"Donor Origin of BK Virus in Renal Transplantation and Role of HLA C7 in Susceptibility to Sustained BK Viremia","volume":"5","author":"Bohl","year":"2005","journal-title":"Am. J. Transplant."}],"container-title":["Journal of Clinical Virology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1386653221002110?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1386653221002110?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,25]],"date-time":"2025-10-25T03:15:37Z","timestamp":1761362137000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1386653221002110"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,10]]},"references-count":45,"alternative-id":["S1386653221002110"],"URL":"https:\/\/doi.org\/10.1016\/j.jcv.2021.104944","relation":{},"ISSN":["1386-6532"],"issn-type":[{"value":"1386-6532","type":"print"}],"subject":[],"published":{"date-parts":[[2021,10]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"JC and Human polyomavirus 9 after kidney transplantation: An exploratory serological cohort study","name":"articletitle","label":"Article Title"},{"value":"Journal of Clinical Virology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.jcv.2021.104944","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2021 The Author(s). Published by Elsevier B.V.","name":"copyright","label":"Copyright"}],"article-number":"104944"}}